- 309 aompkzyqvdrlbcefghsnuj-i-w WecD [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - 198 aomp-zyqvdrlbcefghsnujxit- MutT [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - 50 -o-p----vdr-bcef--s--j---- HcaA1 [PR] COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - 45 ---pkzyq---lbcefgh-nuj--t- LdhA [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases - 71 -o-p-zyq-drlb-efghs--j---- Qor [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases - 215 aompkzyqvd-lbcefghsnujxit- RhaT [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily - 806 aompkzyqvdrlbcefghsnujxitw ProP [GEPR]COG0477 Permeases of the major facilitator superfamily - 7 a---k-------bc-------j---- - [GR] COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzymes - 6 -------------c-fg----j---- - [ER] COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins - 23 a-mpk-yqvdrlb-e-g--------- HIS2 [ER] COG1387 Histidinol phosphatase and related hydrolases of the PHP family - 45 ---pkzyqvdrlbcefg-s-ujx-t- GltD [ER] COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases - 72 aompkzyq-d--bcefghsnujxit- PutP [EHR] COG0591 Na+/proline, Na+/panthothenate symporters and related permeases - 81 ao-pkzy-vdrlb-efghsn-j---w Tdh [ER] COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - 24 --------v--lbcefgh---jxi-- PhnK [EPGR]COG1101 Various ABC transport systems, ATPase components - 52 aompkzyqvd--bcef-hs-uj---- SsnA [FR] COG0402 Cytosine deaminase and related metal-dependent hydrolases - 70 aompkzyq-drlbcefghsnujxitw Hit [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - 8 --mp----vd--bc------------ - [HR] COG2045 Phosphosulfolactate phosphohydrolase and related enzymes - 42 aomp-z-qvdr-bce-g---u--i-- ThiH [HR] COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes - 448 ao-pkzyqvdrlbcefghsnujxi-- FabG [QR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - 484 aompkzyqvdrlbcefghsnujxitw SmtA [QR] COG0500 SAM-dependent methyltransferases - 6 ----k---v-r--c------------ - [R] COG2251 "Predicted RecB family nuclease (associated with helicases in Pyrococcus and Mtub) - 23 -------qvd---cefghsnujxit- - [R] COG1137 ABC-type (unclassified) transport system, ATPase component - 114 aompkzy-vdrlbcefghs-uj---- - [R] COG0842 ABC-type multidrug transport system, permease component - 32 -------q--r--cefghsnujx--- - [R] COG0767 ABC-type toluene export system, permease component - 33 ao-pkz--vd--bc-f--------tw NosY [R] COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component - 123 aom--z-qvdrlbcefghsnujxitw PhnL [R] COG1136 ABC-type transport systems, involved in lipoprotein release, ATPase components - 104 aom----qvdrlbcefghsnujxit- - [R] COG0577 ABC-type transport systems, involved in lipoprotein release, permease components - 22 ao--kz--vd-lb--f-----j--tw - [R] COG3845 ABC-type uncharacterized transport systems, ATPase components - 33 ---------d-lb-efghsnuj-it- NlpA [R] COG1464 ABC-type uncharacterized transport systems, periplasmic component - 3 a-m----------------------- - [R] COG1707 ACT domain-containing protein - 7 --------vd-lb------------- - [R] COG2344 AT-rich DNA-binding protein - 8 a-m-k--------------------- - [R] COG1759 ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases) - 7 a-m-----v----c------------ - [R] COG1606 ATP-utilizing enzymes of the PP-loop superfamily - 88 ------y--drlbcefghsnujxit- Uup [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains - 38 -omp------r--cefg---uj---- - [R] COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase - 14 aompkz---d-lbc------------ - [R] COG1855 ATPases of the PilT family - 57 aompkzyqvdrlbcefghsnuj---w RimI [R] COG0456 Acetyltransferases - 59 -om-k-y-vdrlbcefgh-nuj-i-- WbbJ [R] COG0110 Acetyltransferases (the isoleucine patch superfamily) - 4 -----------l--e--h-------- AphA [R] COG3700 Acid phosphatase (class B) - 5 --------------e-gh-------- - [R] COG3445 Acid-induced glycyl radical enzyme - 48 -o-pkzy-v-rlbcefg----j---- ARA1 [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase - 14 --------------e-gh--u----- DcuB [R] COG2704 Anaerobic C4-dicarboxylate transporter - 51 ---p--y--d---cefghsnujx-t- Arp [R] COG0666 Ankyrin repeat proteins - 4 a-m----------------------- - [R] COG1103 Archaea-specific pyridoxal phosphate-dependent enzymes - 9 aompkz-------------------- - [R] COG1938 Archaeal enzymes of ATP-grasp superfamily - 6 a-m-kz-------------------- - [R] COG1750 Archaeal serine proteases - 13 --m-----v----ce--h-------- AslB [R] COG0641 Arylsulfatase regulator (Fe-S oxidoreductase) - 14 --------v----cef-h---j--t- - [R] COG1512 Beta-propeller domains of methanol dehydrogenase type - 18 ao-------dr--cefgh-nu----- Pta [R] COG0857 BioD-like N-terminal domain of phosphotransacetylase - 4 ----k--qv----------------- - [R] COG2516 Biotin synthase-related enzyme - 9 a-mpkzy------------------- - [R] COG1779 C4-type Zn finger - 202 aompkzyqvdrlbcefghsnujxit- - [R] COG0517 CBS domains - 34 --mpk--q-dr-bcefg-snujx--- PaaY [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily - 43 a-mpkz-qvdrlbcef-h-n-jx--- - [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family - 9 -------q------e--h---j---- DmsC [R] COG3302 DMSO reductase anchor subunit - 10 aompkzy------------------- - [R] COG2118 DNA-binding protein - 10 --------------e-ghs------- Hns [R] COG2916 DNA-binding protein H-NS - 5 -om----------c--g----j---- - [R] COG3046 Deoxyribodipyrimidine photolyase-related proteins - 29 a-----yqvdrlb--f--snuj---- - [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase - 14 a-m-k-y--dr-b-e----------- - [R] COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster - 79 aompkzyqvdrlbcefghsnujxitw ARC1 [R] COG0073 EMAP domain - 22 -----z-qv---bcefghsnujx--- - [R] COG0780 Enzyme related to GTP cyclohydrolase I - 7 -o-------dr-b--------j---- - [R] COG2312 Erythromycin esterase homolog - 4 --------v---b-----------t- - [R] COG1647 Esterase/lipase - 37 aom-kz-qvdrlbc--g-------tw - [R] COG0618 Exopolyphosphatase-related proteins - 8 ------------b-------u----- - [R] COG3401 Fibronectin type 3 domain-containing protein - 9 aom-kzy-v----------------- - [R] COG1635 Flavoproteins, possibly involved in thiazole biosynthesis - 59 aompkzyq-d---c-------j---- - [R] COG1100 GTPases - 31 -------qvdrlbcefghsnujx-tw Era [R] COG1159 GTPases - 28 -om-kz-qvdrlbcefghsn-j-i-- HflX [R] COG2262 GTPases - 7 ------------b-ef-----j---- GsiB [R] COG3729 General stress protein - 23 aompkz-qv--lb------------w - [R] COG1078 HD superfamily phosphohydrolases - 10 ---------dr-bc------uj---- - [R] COG2346 Hemoglobin-like proteins - 12 --------------efg----j--t- Hcp [R] COG3157 Hemolysin-coregulated protein (uncharacterized) - 16 aomp-z-q-dr-b--------j-i-- - [R] COG1331 Highly conserved protein containing a thioredoxin domain - 49 ao--kzy-vdrlb-efg-s--j-i-- - [R] COG1073 Hydrolases of the alpha/beta superfamily - 27 ------y--d-lbcefgh-nujxit- - [R] COG0670 Integral membrane protein, interacts with FtsH - 28 aompkz--vdrlbce---s--j-it- - [R] COG0396 Iron-regulated ABC transporter ATPase subunit SufC - 7 ---------------f----uj---- PcbC [R] COG3491 Isopenicillin N synthase and related dioxygenases - 12 -o-------dr-b--f-----j---- - [R] COG3631 Ketosteroid isomerase-related protein - 13 --------vd----ef-hs--jx--- - [R] COG2373 Large extracellular alpha-helical protein - 23 aompkz----r---ef-----j---- Lhr [R] COG1201 Lhr-like helicases - 11 ----------r-b-efgh--u----- - [R] COG1279 Lysine efflux permease - 59 aompk---vd-lb-efghsn-j---- RfbX [R] COG2244 Membrane protein involved in the export of O-antigen and teichoic acid - 42 -o-pk---vdrlbcef-h--uj---- AbgB [R] COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase - 7 --------------ef--s--j---- ElsH [R] COG3568 Metal-dependent hydrolase - 32 aompk--q---lbcef-----jxit- PhnP [R] COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - 11 a-m-k---v----------------- - [R] COG1237 Metal-dependent hydrolases of the beta-lactamase superfamily II - 38 aompkzy-vdrlbce--h---j-it- ElaC [R] COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III - 70 aompkzyqvdr-bcefg-s--j--t- - [R] COG0714 MoxR-like ATPases - 28 a-m---yq-dr-b-efg-s--j---- WrbA [R] COG0655 Multimeric flavodoxin WrbA - 10 a-m-----------ef-h--uj---- ModE [R] COG2005 N-terminal domain of molybdenum-binding protein - 5 a-m-----v----c------------ - [R] COG1691 NCAIR mutase (PurE)-related proteins - 34 aom-k--q----b---gh-nu--it- - [R] COG0733 Na+-dependent transporters of the SNF family - 6 --------------efgh-------- - [R] COG3081 Nucleoid-associated protein - 11 a-m-kz-----lb---g--------- - [R] COG3291 PKD repeat proteins - 11 --------------efgh-n------ PqiB [R] COG3008 Paraquat-inducible protein B - 3 ------------b---g-----x--- - [R] COG3621 Patatin - 8 -----------lb------------w PrfA [R] COG3331 Penicillin-binding protein-related factor A, putative recombinase - 53 -------q--r--cefghsnujx--- - [R] COG1463 Permease component of an ABC-transporter - 22 ---------d-lb-efghsnuj-it- - [R] COG2011 Permease component of an uncharacterized ABC transporter - 38 -om-k---vd-lb-efgh-nuj--t- - [R] COG2252 Permeases - 8 ------yq--r-b--------j---- - [R] COG2270 Permeases of the major facilitator superfamily - 4 ---------------f--s--j---- - [R] COG3628 Phage baseplate assembly protein W - 7 ----------rl--e------j---- - [R] COG3740 Phage head maturation protease - 4 --------------ef--s------- - [R] COG3500 Phage protein D - 4 --------------ef--s------- - [R] COG3499 Phage protein U - 5 --------------ef--s--j---- - [R] COG3497 Phage tail sheath protein FI - 4 --------------ef--s------- - [R] COG3498 Phage tail tube protein FII - 4 ------------b----h------t- XtmB [R] COG1783 Phage terminase large subunit - 23 --------------e---s--j---- - [R] COG3772 Phage-related lysozyme (muraminidase) - 29 aompk-yq--r-b-e-ghsnuj-i-w - [R] COG1881 Phospholipid-binding protein - 19 ---p------r--cefgh---j---- - [R] COG1741 Pirin-related protein - 4 ----kz--v----------------- - [R] COG2446 Predicted ABC-type transport system, periplasmic component - 3 a-m----------------------- - [R] COG2232 Predicted ATP-dependent carboligases related to biotin carboxylase - 3 a-m----------------------- - [R] COG1821 Predicted ATP-utilizing enzymes of ATP-grasp superfamily - 39 aompkz-qvdrlbcef-h---j---- - [R] COG0433 Predicted ATPase - 15 ------y--dr---efg-sn-jx--- - [R] COG1485 Predicted ATPase - 6 --m-----------ef----u----- - [R] COG2603 Predicted ATPase - 6 --------------e-gh---j---- - [R] COG3106 Predicted ATPase - 7 -o--------rl--e---s------- - [R] COG3378 Predicted ATPase - 31 aompkz-q----bcefghsnujx--- - [R] COG0603 Predicted ATPase (PP-loop superfamily), confers aluminum resistance - 39 --m-k---v----------------- - [R] COG1672 Predicted ATPase of the AAA superfamily - 6 a---kz--v----------------- - [R] COG1483 Predicted ATPase of the AAA+ class - 8 -------q-----c-f---nuj---- - [R] COG2607 Predicted ATPase of the AAA+ class - 3 --m--z----------g--------- - [R] COG3044 Predicted ATPase of the ABC class - 29 -------qvdrlbcefghsnujxit- - [R] COG0802 Predicted ATPase or kinase - 7 --m-k---------------u----- - [R] COG1106 Predicted ATPases - 14 aompkzy------------------- - [R] COG2102 Predicted ATPases of PP-loop superfamily - 10 a-mpkz-qv----------------- - [R] COG1618 Predicted ATPases or kinases - 17 -o-pkz-qvd-lb-e-----uj---- - [R] COG1832 Predicted CoA-binding protein - 23 ao-p---------------------- - [R] COG3413 Predicted DNA binding domain - 4 --m---------b------------- - [R] COG3849 Predicted DNA binding protein - 11 aompkz-------------------- - [R] COG1571 Predicted DNA-binding protein containing a Zn-ribbon domain - 6 a-m-k-----------g--------- - [R] COG1342 Predicted DNA-binding proteins - 11 aompkz--------e-g----j---- - [R] COG1661 Predicted DNA-binding proteins with PD1-like DNA-binding motif - 5 a-m-kz-------------------- - [R] COG2100 Predicted Fe-S oxidoreductase - 53 aompkz-qvdrlbc-f-----j---- - [R] COG0535 Predicted Fe-S oxidoreductases - 8 aompk--------------------- - [R] COG1244 Predicted Fe-S oxidoreductases - 10 a-mpkz----r--------------- - [R] COG1964 Predicted Fe-S oxidoreductases - 8 --------------efg----j---- - [R] COG3313 Predicted Fe-S protein - 3 --m-----v----------------- - [R] COG2000 Predicted Fe-S proteins - 28 aom-k----d-l-cef--s-uj---- - [R] COG0727 Predicted Fe-S-cluster oxidoreductase - 30 -------qvdrlbcefghsnuj--tw - [R] COG0820 Predicted Fe-S-cluster redox enzyme - 46 aompkzyqvdrlbcefghsnujxitw - [R] COG0012 Predicted GTPase - 32 ------yqvd-lbcefghsnujxitw ThdF [R] COG0486 Predicted GTPase - 34 ------yqvdrlbcefghsnujxitw Obg [R] COG0536 Predicted GTPase - 10 aompkzy------------------- - [R] COG1084 Predicted GTPase - 11 aompkzy------------------- - [R] COG1163 Predicted GTPase - 8 --m----q-dr--------n------ - [R] COG2229 Predicted GTPase - 10 -------------ce-g--nu----- - [R] COG3596 Predicted GTPase - 7 a-m-kzy------------------- - [R] COG1341 Predicted GTPase or GTP-binding protein - 31 aom-k-yqv--lb-efghsnujx--w - [R] COG0218 Predicted GTPases - 34 -------qvdrlbcefghsnujxitw - [R] COG1160 Predicted GTPases - 28 --m-kzy-v--lbc--g--n----tw - [R] COG1161 Predicted GTPases - 24 -------qv-rlbcefghsn-j--tw - [R] COG1162 Predicted GTPases - 24 ------y--dr-bcef----u----- - [R] COG0699 Predicted GTPases (dynamin-related) - 31 aompk--qvd-lb-e-----u---tw - [R] COG1418 Predicted HD superfamily hydrolase - 3 a-------vd---------------- - [R] COG2316 Predicted HD superfamily hydrolase - 3 --------------e------j---- - [R] COG3810 Predicted HD superfamily hydrolase - 6 --m--------lb------------- - [R] COG3481 Predicted HD-superfamily hydrolase - 15 aompkz---------------j---- - [R] COG1407 Predicted ICC-like phosphoesterases - 7 ----------r-----g--n-j---- - [R] COG2907 Predicted NAD/FAD-binding protein - 3 -o-----------c-f---------- - [R] COG3380 Predicted NAD/FAD-dependent oxidoreductase - 18 ------yq--r-bcef---n-j---- - [R] COG0385 Predicted Na+-dependent transporter - 8 ------------b-e-gh--u---t- - [R] COG1823 Predicted Na+/dicarboxylate symporter - 14 ao--kzy-------e-gh-------- - [R] COG1444 Predicted P-loop ATPase fused to an acetyltransferase - 16 ---------drlb-efghsn------ - [R] COG1660 Predicted P-loop-containing kinase - 16 -----------lb-efghsn-j--tw - [R] COG2183 Predicted RNA binding protein, contains S1 domain - 11 --------vdrlbc----------t- Jag [R] COG1847 Predicted RNA-binding protein - 19 -------qvdrlbc------u--it- - [R] COG1837 Predicted RNA-binding protein (KH domain) - 11 aompkzy------------------- - [R] COG1094 Predicted RNA-binding protein (contains KH domains) - 4 -----------lbc------------ - [R] COG3688 Predicted RNA-binding protein containing a PIN domain - 10 a-m-kzy------------------- - [R] COG1818 Predicted RNA-binding protein, contains THUMP domain - 3 a-m----------------------- - [R] COG1532 Predicted RNA-binding proteins - 11 aompkzy------------------- - [R] COG1537 Predicted RNA-binding proteins - 34 a--pk-yqvdrlb-efghsnuj-i-- - [R] COG1611 Predicted Rossmann fold nucleotide-binding protein - 33 ------yqvdrlbcefghsnujxitw - [R] COG0220 Predicted S-adenosylmethionine-dependent methyltransferase - 9 ---------d-lb---g--------w - [R] COG2384 Predicted SAM-dependent methyltransferase - 6 --------------ef-hs------- - [R] COG2933 Predicted SAM-dependent methyltransferase - 33 --m-kz-qvd-lb-efghsn-j-i-- - [R] COG1092 Predicted SAM-dependent methyltransferases - 4 --------------efg--------- - [R] COG3129 Predicted SAM-dependent methyltransferases - 9 aom-kz-------ce------j---- SgcQ [R] COG0434 Predicted TIM-barrel enzyme - 59 aom---yqvdrlbcefghsnujxit- - [R] COG0042 Predicted TIM-barrel enzymes, possibly dehydrogenases, nifR3 family - 40 aompkzy-vdrlbcefghs-uj---- - [R] COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold - 58 -----zyqvdrlbcefghs-ujx-t- PqqL [R] COG0612 Predicted Zn-dependent peptidases - 7 ------y--d-------------it- - [R] COG1026 Predicted Zn-dependent peptidases, insulinase-like - 5 --------vd--b------------- - [R] COG2738 Predicted Zn-dependent protease - 9 aom-kz-q------------------ - [R] COG1913 Predicted Zn-dependent proteases - 65 a-mpkz-qvdr-bcefghsn-j---- TldD [R] COG0312 Predicted Zn-dependent proteases and their inactivated homologs - 11 a----z---d-l--efgh---j---- - [R] COG2388 Predicted acetyltransferase - 11 -----------l--efg----j---- - [R] COG3153 Predicted acetyltransferase - 3 ----------r-b-----------t- - [R] COG3393 Predicted acetyltransferase - 3 ------------------s--j---- - [R] COG3818 Predicted acetyltransferase, GNAT superfamily - 21 a-----y--d--bc-fg-s------w LipA [R] COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold - 10 ----------rl-c----s--j---- - [R] COG2936 Predicted acyl esterases - 8 ----------rlbcefg--------- ElaA [R] COG2153 Predicted acyltransferases - 10 a-mpkz-qv----------------- - [R] COG1350 Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) - 77 aompkzyqvdr-bcefg-snuj--t- - [R] COG0388 Predicted amidohydrolase - 26 -------qvdrlbcefghsnuj--t- ComFC [R] COG1040 Predicted amidophosphoribosyltransferases - 11 -o-------dr-b--f-----j---- - [R] COG3173 Predicted aminoglycoside phosphotransferase - 19 ------yq-dr--cefghsn-jx--- - [R] COG0354 Predicted aminomethyltransferase related to GcvT - 29 aom-k-yq--r-b-efg-s--j---- Iap [R] COG2234 Predicted aminopeptidases - 9 aompkz-------------------- - [R] COG1608 Predicted archaeal kinases - 7 aom-kz-------------------- - [R] COG1829 Predicted archaeal kinases of the sugar kinase superfamily - 5 --m-kz------------s------- - [R] COG2521 Predicted archaeal methyltransferase - 9 a-m-kz-------------------- - [R] COG1907 Predicted archaeal sugar kinases - 6 ---------------f-----jx--- - [R] COG3577 Predicted aspartyl protease - 3 ---------d-----f-h-------- - [R] COG3179 Predicted chitinase - 5 --m-k-----r----f---------- - [R] COG3233 Predicted deacetylase - 5 -o--------------g----j---- - [R] COG3608 Predicted deacylase - 27 a--pkz--v-r-bcefg-snuj---w - [R] COG0579 Predicted dehydrogenase - 99 --mpk-yqvd-lbcefgh--uj---- MviM [R] COG0673 Predicted dehydrogenases and related proteins - 10 aom--------l------s--j---- - [R] COG2085 Predicted dinucleotide-binding enzymes - 5 a-m-----v------f---------- - [R] COG1712 Predicted dinucleotide-utilizing enzyme - 13 a-mpkzyqv------------j---- - [R] COG1355 Predicted dioxygenase - 3 -------------c-f-----j---- - [R] COG3565 Predicted dioxygenase of extradiol dioxygenase family - 16 --m------------f---nu----- - [R] COG3271 Predicted double-glycine peptidase - 3 ------y-v---b------------- - [R] COG3341 Predicted double-stranded RNA/RNA-DNA hybrid binding protein - 25 ---p-z---dr-b------------- - [R] COG2409 Predicted drug exporters of the RND superfamily - 13 --------v------f-----j---- - [R] COG3450 Predicted enzyme of the cupin superfamily - 12 ----------r-b--fgh---j---- - [R] COG3324 Predicted enzyme related to lactoylglutathione lyase - 26 ------yqvdrlbcefghsnuj---- - [R] COG0325 Predicted enzyme with a TIM-barrel fold - 24 -o----y--dr-bcefgh---j---- - [R] COG0384 Predicted epimerase, PhzC/PhzF homolog - 15 ------y--d-lbcef--s--jxi-- - [R] COG0400 Predicted esterase - 24 ------y---rl-cef-h-n-j---- - [R] COG0627 Predicted esterase - 8 --------------efgh-------- - [R] COG3150 Predicted esterase - 40 ------yqv-rlbcefghsn-jx-t- RssA [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily - 7 ---------d--b--f-----j---- - [R] COG3545 Predicted esterase of the alpha/beta hydrolase fold - 13 aom-k---v---b--f----u---t- - [R] COG1033 Predicted exporters of the RND superfamily - 6 ---------d-l-c-fg-------t- - [R] COG2374 Predicted extracellular nuclease - 15 -omp------rlb------n-j---- - [R] COG3467 Predicted flavin-nucleotide-binding protein - 11 --m------drl---f-----j---- - [R] COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - 34 -o----y--drlbcefgh-n-j---w - [R] COG0431 Predicted flavoprotein - 14 -----------lbcefgh---j---- - [R] COG2081 Predicted flavoproteins - 21 --mpk-y---r--cefgh-n-j---- - [R] COG0121 Predicted glutamine amidotransferase - 5 ----------rl-c------------ - [R] COG3442 Predicted glutamine amidotransferase - 13 ----------rl--ef----ujx--- - [R] COG2071 Predicted glutamine amidotransferases - 23 a-m-kz---dr--cef--s--j---- - [R] COG1216 Predicted glycosyltransferases - 17 a-m-kz-qv--lb-e--h-------- - [R] COG1203 Predicted helicases - 15 aompkzyq------------------ - [R] COG1204 Predicted helicases - 12 --m----q-----c------------ - [R] COG1719 Predicted hydrocarbon binding protein (contains V4R domain) - 7 --------------efgh-------- - [R] COG3083 Predicted hydrolase of alkaline phosphatase superfamily - 8 ------y-vd-lbc------------ - [R] COG2179 Predicted hydrolase of the HAD superfamily - 10 a-mpk--qv-r-b------------- - [R] COG1353 Predicted hydrolase of the HD superfamily (permuted catalytic motifs) - 8 ---------d--b-ef---nuj---- - [R] COG2819 Predicted hydrolase of the alpha/beta superfamily - 9 ao-------------f--sn-jx--- - [R] COG2945 Predicted hydrolase of the alpha/beta superfamily - 10 ------y------cefg--n------ - [R] COG0429 Predicted hydrolase of the alpha/beta-hydrolase fold - 3 ----------r----f-----j---- - [R] COG3571 Predicted hydrolase of the alpha/beta-hydrolase fold - 33 -om-k---vdrlbc------ujx--w - [R] COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily - 5 a-m-kz-------------------- - [R] COG2248 Predicted hydrolase of the metallo-beta-lactamase superfamily - 16 ao--kzy--d----efgh--u----- - [R] COG1896 Predicted hydrolases of HD superfamily - 17 -o-------d-lb-efghsn------ ComEC [R] COG2333 Predicted hydrolases of metallo-beta-lactamase fold - 89 aompkzy-vdrlbce-gh-n-j-itw Cof [R] COG0561 Predicted hydrolases of the HAD superfamily - 82 -ompk-yqvdrlb-efghsn-j--t- - [R] COG1011 Predicted hydrolases of the HAD superfamily - 5 ----kz--------e----------- - [R] COG3769 Predicted hydrolases of the HAD superfamily - 257 ao-p-zyq-drlbcefghsnujx-tw MhpC [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) - 33 aom-k--qv-r-bcef--s--j---w - [R] COG0392 Predicted integral membrane protein - 46 aompkzyqv-rlbcefghsnujx-tw - [R] COG0061 Predicted kinase - 11 -o-----q-dr--c-f-----j---- - [R] COG0645 Predicted kinase - 29 ---p--y-vdrlbcef-----j---- BmrU [R] COG1597 Predicted kinase related to diacylglycerol kinase - 12 --------vdrlb------------w - [R] COG1461 Predicted kinase related to dihydroxyacetone kinase - 7 ---p------r--c------u----- - [R] COG2605 Predicted kinase related to galactokinase and mevalonate kinase - 18 a-m---yqvdrlbc-f---n-j---- ArgJ [R] COG1364 Predicted kinase related to thiamine pyrophosphokinase - 3 -----------lb--------j---- - [R] COG3607 Predicted lactoylglutathione lyase - 51 aompkz--vdrlbce---s--j-it- - [R] COG0719 Predicted membrane components of an uncharacterized iron-regulated ABC-type transporter SufB - 10 --mp--y-------e-gh-------- - [R] COG1584 Predicted membrane protein - 4 -----------lb-----------t- PfoR [R] COG3641 Predicted membrane protein, putative toxin regulator - 21 ------y--drlb-efg-sn-j--t- - [R] COG1272 Predicted membrane proteins, hemolysin III homologs - 6 --------v---bc---------it- - [R] COG1480 Predicted membrane-associated HD superfamily hydrolase - 33 ----k---------efghsnu-x--- - [R] COG2194 Predicted membrane-associated, metal-dependent hydrolase - 13 a-m-k-------b-ef---------- - [R] COG1988 Predicted membrane-bound metal-dependent hydrolases - 10 ------------b-efg--n---i-- - [R] COG3318 Predicted metal-binding protein related to the C-terminal domain of SecA - 17 -------qvdr-bcefghsn------ - [R] COG1399 Predicted metal-binding, possibly nucleic acid-binding protein - 9 aompkz-------------------- - [R] COG1782 Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain - 33 -------qvdrlbcefghsnujxitw - [R] COG0319 Predicted metal-dependent hydrolase - 28 aom-k--q-d----efg-snuj---w - [R] COG1451 Predicted metal-dependent hydrolase - 5 ----------r----f-----j---- - [R] COG3687 Predicted metal-dependent hydrolase - 11 -o--kz----r--c-------j---- - [R] COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold - 5 ---------------f----uj---- - [R] COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold - 17 -o-pkz-qvdr-b--f-----j---- - [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold - 7 ---------dr-b-e------j---w Php [R] COG1735 Predicted metal-dependent hydrolase with the TIM-barrel fold - 9 aompkz-------------------- - [R] COG1831 Predicted metal-dependent hydrolases of the urease superfamily - 18 ---pkzy-vd--b--fg----j---- - [R] COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain - 4 a-m----------------------- - [R] COG1099 Predicted metal-dependent hydrolases with the TIM-barrel fold - 48 -om-kz-qvdrlbcefg----j-it- - [R] COG1266 Predicted metal-dependent membrane protease - 24 aom--z-qvd--bcefgh-n------ - [R] COG0613 Predicted metal-dependent phosphoesterases (PHP family) - 22 --mpkz--vdrlb-e---s--j---- PaaD [R] COG2151 Predicted metal-sulfur cluster biosynthetic enzyme - 9 ---------drl--ef-h---j---- - [R] COG2321 Predicted metalloprotease - 22 aompkzy------------------- - [R] COG2520 Predicted methyltransferase - 35 -------qvdrlbcefghsnujxitw - [R] COG0313 Predicted methyltransferases - 6 a-m-k--q------------------ - [R] COG1568 Predicted methyltransferases - 35 -------q-drlbcefghsnujxi-- Rbn [R] COG1295 Predicted multitransmembrane protein - 30 -------qvdrlbcefghsnuj-itw ComEC [R] COG0658 Predicted multitransmembrane, metal-binding protein - 6 ao----y------------------- - [R] COG3582 Predicted nucleic acid binding protein containing the AN1-type Zn-finger - 10 aompkzy------------------- - [R] COG1439 Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module - 4 a------qv---b------------- - [R] COG1367 Predicted nucleic acid-binding protein, contains PIN domain - 34 a-m-k----dr--c---hs--j---- VapC [R] COG1487 Predicted nucleic acid-binding protein, contains PIN domain - 8 a-m-k--------c----s------- - [R] COG1569 Predicted nucleic acid-binding protein, contains PIN domain - 38 a-m-kz----r--------------- - [R] COG1848 Predicted nucleic acid-binding protein, contains PIN domain - 11 ao--k--q--r--c------------ - [R] COG2402 Predicted nucleic acid-binding protein, contains PIN domain - 5 a----z-------c------------ - [R] COG2405 Predicted nucleic acid-binding protein, contains PIN domain - 4 --------v-r-b------------- - [R] COG1623 Predicted nucleic-acid-binding protein (contains the HHH domain) - 30 aompkz----r----------j---- - [R] COG1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon - 3 --m--------lb------------- - [R] COG3478 Predicted nucleic-acid-binding protein containing a Zn-ribbon domain - 3 --------------efg--------- - [R] COG3529 Predicted nucleic-acid-binding protein containing a Zn-ribbon domain - 13 ---p------r-bcef-hs------- - [R] COG1090 Predicted nucleoside-diphosphate sugar epimerases (SulA family) - 3 a-m----------------------- - [R] COG1548 Predicted nucleotide-binding enzyme - 23 ao-pkzy-vdrlbce-g--n-j---- CinA [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - 9 aompk-y------------------- - [R] COG1019 Predicted nucleotidyltransferase - 4 a---kz-------------------- - [R] COG2413 Predicted nucleotidyltransferase - 4 --m---------b--f-----j---- - [R] COG3541 Predicted nucleotidyltransferase - 16 a-m-----vd---c-----n-j---- - [R] COG1669 Predicted nucleotidyltransferases - 34 a-m-kz-qv--------h-------- - [R] COG1708 Predicted nucleotidyltransferases - 3 ---------dr----------j---- - [R] COG3573 Predicted oxidoreductase - 6 ------y----l---f---n------ FMR2 [R] COG3560 Predicted oxidoreductase related to nitroreductase - 4 --m-----v----c------------ - [R] COG1453 Predicted oxidoreductases of the aldo/keto reductase family - 18 ao---z---d--bc-fgh----x--- - [R] COG2358 Predicted periplasmic binding protein - 3 --m-------------g---u----- - [R] COG2998 Predicted periplasmic ligand-binding protein - 12 --------------efgh-n--x--- OsmY [R] COG2823 Predicted periplasmic or secreted lipoprotein - 5 -----------lb-e----------- - [R] COG3443 Predicted periplasmic or secreted protein - 12 a--p-z-q-d--b-------u--i-- - [R] COG1427 Predicted periplasmic solute-binding protein - 25 -------q-drlb-efghsnujx-t- - [R] COG1559 Predicted periplasmic solute-binding protein - 12 a--p-z-q-d--b-------u--i-- - [R] COG2107 Predicted periplasmic solute-binding protein - 8 --m----qv-r-bce----------- - [R] COG0390 Predicted permease - 71 aom-k--qvdrlbcefghsnujx-t- PerM [R] COG0628 Predicted permease - 12 ------------b--fgh-nu----- - [R] COG2056 Predicted permease - 8 -o------------e-gh-------- - [R] COG2985 Predicted permease - 4 ----------r-bc-------j---- - [R] COG3329 Predicted permease - 6 a--pk--------------------- - [R] COG3368 Predicted permease - 26 --m---yqv---bcefghs-ujx--- - [R] COG0679 Predicted permeases - 14 a-m----qv-rlbce-----u----- - [R] COG0701 Predicted permeases - 93 aompkz-qvdrlbcefghsnuj---- - [R] COG0730 Predicted permeases - 46 --------vd---cefghsnujxit- - [R] COG0795 Predicted permeases - 12 ------------b-efgh---j---- RarD [R] COG2962 Predicted permeases - 7 a-m----q-------f---------- - [R] COG2044 Predicted peroxiredoxins - 7 ------------b--fg---uj---- PhoX [R] COG3211 Predicted phosphatase - 54 ----k-y-vdrlbcefghsn-j-i-- - [R] COG0637 Predicted phosphatase/phosphohexomutase - 52 aom-k-yq-drlbcefghsnuj--tw Gph [R] COG0546 Predicted phosphatases - 12 aompkz------b------------- - [R] COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold - 29 aom-kzy-v-rlb-efg-------tw - [R] COG0622 Predicted phosphoesterase - 8 aom-kz-q------------------ - [R] COG2129 Predicted phosphoesterases, related to the Icc protein - 6 -o---z------b-------u----- - [R] COG2404 Predicted phosphohydrolase of the DHH superfamily - 18 --m----q-drlb-e-----uj-i-- - [R] COG1408 Predicted phosphohydrolases - 30 a-m-kzyq--r--cefgh---j-i-- Icc [R] COG1409 Predicted phosphohydrolases - 5 --m----q-d-------------i-- - [R] COG1768 Predicted phosphohydrolases - 9 ---p---q--r---------uj---- - [R] COG1926 Predicted phosphoribosyltransferases - 20 ao-pkzy------------nu---t- - [R] COG2236 Predicted phosphoribosyltransferases - 6 ---------------f--sn-j---- - [R] COG3178 Predicted phosphotransferases related to Ser/Thr protein kinases - 38 a---kz-qvdrlbcefghs--j-it- MazG [R] COG1694 Predicted pyrophosphatase - 11 aompk--------------------- - [R] COG2150 Predicted regulator of amino acid metabolism, contains ACT domain - 6 -----z---d-lb--------j---- - [R] COG2514 Predicted ring-cleavage extradiol dioxygenase - 6 --m-----v--lb------------- - [R] COG1827 Predicted small molecule binding protein (contains 3H domain) - 13 ---------d-lbce-gh---j---- - [R] COG2103 Predicted sugar phosphate isomerase - 45 -omp-z-q-dr-bcefghsnuj--t- FcbC [R] COG0824 Predicted thioesterase - 7 ao--kz-------------------- - [R] COG2522 Predicted transcriptional regulator - 5 --------------e-gh-------- - [R] COG3054 Predicted transcriptional regulator - 4 ----------r----------j---- - [R] COG3800 Predicted transcriptional regulator - 6 a-m-k--------------------- - [R] COG1800 Predicted transglutaminase-like proteases - 29 -o-p----vd----efg-s-uj---- - [R] COG2391 Predicted transporter components - 30 -omp--y---r-bcefghsn-jx--- AarF [R] COG0661 Predicted unusual protein kinase - 13 -o--------r-b-efgh-n-j---- FxsA [R] COG3030 Protein affecting phage T7 exclusion by the F plasmid - 11 a------q-d--bce------j---- - [R] COG2304 Protein containing von Willebrand factor (vWF) type A domain - 11 --------------efghsn-j---- ComJ [R] COG2961 Protein involved in catabolism of external DNA - 13 a--p-z---d---c-f-----j---- - [R] COG2366 Protein related to penicillin acylase - 9 ------y-----------s--j-i-- - [R] COG2940 Proteins containing SET domain - 28 ------yq-dr-bcefg-snuj---- - [R] COG0523 Putative GTPases (G3E family) - 9 -----------lb-efg-s-uj---- - [R] COG2910 Putative NADH-flavin reductase - 9 -o----y-----b-ef-----j---- - [R] COG2130 Putative NADP-dependent oxidoreductases - 35 ------------b-efgh-nuj---w MdaB [R] COG2249 Putative NADPH-quinone reductase (modulator of drug activity B) - 7 ------------b-efg----j---- AbrB [R] COG3180 Putative ammonia monooxygenase - 17 ----k----d-lb-efgh-n------ - [R] COG1380 Putative effector of murein hydrolase LrgA - 14 ---------d--bcefg--n-j---- - [R] COG2334 Putative homoserine kinase type II (protein kinase fold) - 76 aompkzyq-dr-bcefghs-uj--tw ThiJ [R] COG0693 Putative intracellular protease/amidase - 7 --------------efghs------- LppC [R] COG3107 Putative lipoprotein - 10 aompkzy------------------- - [R] COG1245 RNase L inhibitor homolog, predicted ATPase - 8 --------------e-ghsn------ - [R] COG3113 STAS domain protein - 4 --m----------c------------ - [R] COG2144 Selenophosphate synthetase-related proteins - 31 -o----y---rlb-ef-hsnuj---- DltE [R] COG0300 Short-chain dehydrogenases of various substrate specificities - 5 -om-k--------------------- - [R] COG1202 Specific archaeal helicases - 9 --------------efghsn------ SspB [R] COG2969 Stringent starvation protein B - 16 ---------dr--cefghs--j-i-- - [R] COG2166 SufE protein probably involved in Fe-S center assembly - 28 aom--zyqvd---cefghsnuj-it- SurE [R] COG0496 Survival protein, predicted acid phosphatase - 57 ------y--d----efgh-nuj---- - [R] COG0790 TPR repeat proteins - 294 aompk-yqvd-lbcefghsnujxit- NrfG [R] COG0457 TPR-repeat-containing proteins - 9 ---------d--b-ef----uj---- - [R] COG2351 Transthyretin-like protein - 24 ---------d-lbcefghsnuj-it- Abc [R] COG1135 Uncharacterized ABC-type transport system ATPase component - 48 ao--kz--vd-lb--f-----j--tw - [R] COG1079 Uncharacterized ABC-type transport system, permease component - 4 a---kz-------------------- - [R] COG2401 Uncharacterized ABC-type transporter - 19 aom-k---vd-lbc-------jxit- BioY [R] COG1268 Uncharacterized ACR - 6 aom-kz-------------------- - [R] COG2108 Uncharacterized ACR related to pyruvate formate-lyase activating enzyme - 16 --m----qv---b-efghsn-j---- Hfq [R] COG1923 Uncharacterized ACR, host factor I protein - 18 aompk---v-r-bc-f-h---j---- - [R] COG1878 Uncharacterized ACR, predicted metal-dependent hydrolases - 17 a-m----q-dr--------n------ - [R] COG2018 Uncharacterized ACR; distantly related to eukaryotic homeotic protein bithoraxoid - 5 ---------d-------h-n------ - [R] COG2842 Uncharacterized ATPase, putative transposase - 23 --mpk---v-r------h--uj---- - [R] COG1373 Uncharacterized ATPases of the AAA superfamily - 4 --m-k--------------------- - [R] COG1365 Uncharacterized ATPases of the PP-loop superfamily - 4 a-m-k--------------------- - [R] COG2517 Uncharacterized ArCR (contains C-terminal EMAP domain) - 17 --------vdrlb-efgh-n----t- OraA [R] COG2137 Uncharacterized BCR - 4 --------------e-g----j---- - [R] COG3788 Uncharacterized BCR related to glutathione S-transferase, MAPEG superfamily - 9 ---------dr--c----s--jx-t- - [R] COG1754 Uncharacterized C-terminal domain of topoisomerase IA - 9 a---k---v--lbc--g----j---- - [R] COG2509 Uncharacterized FAD-dependent dehydrogenases - 3 a-m-----v----------------- - [R] COG2768 Uncharacterized Fe-S center protein - 10 --m----qv--lb-e-g--------- - [R] COG1242 Uncharacterized Fe-S oxidoreductases - 7 -o------------efg----j---- - [R] COG3217 Uncharacterized Fe-S protein - 9 a-m-kz-qv----------------- PflX [R] COG1313 Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins - 4 --------------e-g---u----- Bax [R] COG2992 Uncharacterized FlgJ-related protein - 11 --m--z---dr-b-e------j---- - [R] COG2068 Uncharacterized MobA-related protein - 98 aompkzyqvdrlbcefgh---j--tw HcaD [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases - 9 aompkz-------------------- - [R] COG1634 Uncharacterized Rossmann fold enzyme - 6 aom-kz-------------------- - [R] COG1645 Uncharacterized Zn-finger containing protein - 6 --mp--------b--------j---- - [R] COG3383 Uncharacterized anaerobic dehydrogenase - 3 a-m----------------------- - [R] COG2054 Uncharacterized archaeal kinases related to aspartokinases, uridylate kinases - 14 -o------------e-gh-------- TorD [R] COG3381 Uncharacterized component of anaerobic dehydrogenases - 18 -o-p-z---dr-b--f-----j---- - [R] COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides - 16 ---------d-lbcefg-s--jxi-- - [R] COG1054 Uncharacterized enzyme related to sulfurtransferases - 21 ao-p-z-q-dr-b-ef-h--uj---- - [R] COG2041 Uncharacterized enzymes, related to nitrate reductase - 14 -o-------d--b-e---s--j---- - [R] COG2311 Uncharacterized membrane protein - 7 ---------d--b----h-------- - [R] COG2364 Uncharacterized membrane protein - 39 aompkzyqvdrlbcefghs-uj--t- GlpG [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid) - 5 --------------efg----j---- GlpM [R] COG3136 Uncharacterized membrane protein required for alginate biosynthesis - 7 a-------vd--b-e----------- - [R] COG1811 Uncharacterized membrane protein, possible Na+ channel or pump - 28 -------qvdr--cefghsnujxit- MviN [R] COG0728 Uncharacterized membrane protein, putative virulence factor - 18 aompk-y-------------u----- - [R] COG1287 Uncharacterized membrane protein, required for N-linked glycosylation - 17 ------------b-efghsnuj--t- CvpA [R] COG1286 Uncharacterized membrane protein, required for colicin V production - 4 ------------bc-f---------- SpmA [R] COG2715 Uncharacterized membrane protein, required for spore maturation in B.subtilis. - 29 -o-----qvdrlbcefg-snuj---w CinA [R] COG1546 Uncharacterized protein (competence- and mitomycin-induced) - 24 -o---zyq-d--b--fg-snujx--- - [R] COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems - 17 --mp-zy---r-b-ef-----j---- PrpD [R] COG2079 Uncharacterized protein involved in propionate catabolism - 8 --------------efghs------- - [R] COG2915 Uncharacterized protein involved in purine metabolism - 9 --------------e--h-n-j---- HipA [R] COG3550 Uncharacterized protein related to capsule biosynthesis enzymes - 18 a-m--------lb-e---snuj---- - [R] COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog - 6 ---------d--b-e------j---- CopC [R] COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC - 14 -om--z--v-r-bc-------j---- - [R] COG1402 Uncharacterized protein, putative amidase - 7 ---------dr--c-fg----j---- - [R] COG2802 Uncharacterized protein, similar to the N-terminal domain of Lon protease - 13 -------q------efghsnu----- - [R] COG1778 Uncharacterized proteins of HAD superfamily, CMP-Neu5Ac homologs - 11 aompkzy------------------- - [R] COG1412 Uncharacterized proteins of PilT N-term./Vapc superfamily - 21 a--pk-y-v---b--f--s-uj---- - [R] COG1524 Uncharacterized proteins of the AP superfamily - 8 aompk--------------------- - [R] COG2047 Uncharacterized proteins of the ATP-grasp superfamily - 16 ----k----dr-b-efgh-nu----- - [R] COG1540 Uncharacterized proteins, homologs of lactam utilization protein B - 6 --m--z----r----------j---- CoxE [R] COG3552 Von Willebrand A-domain-containing protein - 86 ------y-vd---c--g----j---- - [R] COG2319 WD40 repeat protein - 16 a-m-k--q-d---ce-----u----- HybF [R] COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) - 37 ---p-zy---rlbcef--snuj---- AdhP [R] COG1064 Zn-dependent alcohol dehydrogenases - 156 aompkzyqvdrlbcefghsnuj---- GloB [R] COG0491 Zn-dependent hydrolases, including glyoxylases - 27 aompkz-qvdr-bc--g--nuj---- SpoIVFB [R] COG1994 Zn-dependent proteases - 3 a-m----------------------- - [R] COG2158 Zn-finger-like domain - 3 aom----------------------- - [R] COG3364 Zn-ribbon containing protein - 11 -------q-dr---------u--it- - [R] COG1579 Zn-ribbon protein, possibly nucleic acid-binding