y a o g oooooooooooooooooooooooooooooooooooooo 1 5 5 5 |||---||------------------------------ 12 [C] COG1029 Formylmethanofuran dehydrogenase subunit B 1 5 5 5 |||---||------------------------------ 8 [C] COG1036 Archaeal flavoproteins 3 4 5 13 --------------|-----|---|||----------- 13 [L] COG1039 Ribonuclease HIII 3 5 5 7 --|--------------|-------------|-||--- 9 [M] COG1083 CMP-N-acetylneuraminic acid synthetase 3 4 5 10 ---------------|--|----|||------------ 14 [J] COG1098 Predicted RNA binding protein (contains ribosomal protein S1 domain) 2 5 5 5 ||----||--------|--------------------- 7 [R] COG1099 Predicted metal-dependent hydrolases with the TIM-barrel fold 1 5 5 5 |||---||------------------------------ 6 [R] COG1103 Archaea-specific pyridoxal phosphate-dependent enzymes 1 5 5 5 |||---||------------------------------ 10 [C] COG1152 CO dehydrogenase/acetyl-CoA synthase alpha subunit 1 5 5 5 |||---||------------------------------ 9 [C] COG1153 Formylmethanofuran dehydrogenase subunit D 1 5 5 5 |||---||------------------------------ 5 [R] COG1223 Predicted ATPase (AAA+ superfamily) 1 5 5 5 |||---||------------------------------ 7 [C] COG1229 Formylmethanofuran dehydrogenase subunit A 1 5 5 6 ||-|-||------------------------------- 6 [S] COG1255 Uncharacterized protein conserved in archaea 4 5 5 9 ------|---------------|-|--|--------|- 18 [S] COG1273 Uncharacterized conserved protein 4 5 5 6 ---------------|-----|-||-----|------- 6 [L] COG1315 Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain 4 5 5 6 ---------------|-----|-||-----|------- 6 [N] COG1406 Predicted inhibitor of MCP methylation, homolog of CheC 1 5 5 5 |||---||------------------------------ 5 [R] COG1411 Uncharacterized protein related to proFAR isomerase (HisA) 1 5 5 5 |||---||------------------------------ 6 [C] COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein) 1 5 5 6 |-|--|||------------------------------ 7 [S] COG1504 Uncharacterized conserved protein 3 5 5 8 -|---|------------------|-------|---|- 11 [K] COG1510 Predicted transcriptional regulators 1 5 5 5 |||---||------------------------------ 5 [KG] COG1548 Predicted transcriptional regulator/sugar kinase 4 5 5 9 ---------------|--|---|||------------- 9 [S] COG1550 Uncharacterized protein conserved in bacteria 2 5 5 6 |-|--||---------|--------------------- 9 [S] COG1572 Uncharacterized conserved protein 1 5 5 5 |||---||------------------------------ 7 [C] COG1614 CO dehydrogenase/acetyl-CoA synthase beta subunit 4 5 5 8 ------|---------||----||-------------- 11 [S] COG1615 Uncharacterized conserved protein 4 5 5 8 ---------------|---|--|||------------- 8 [R] COG1623 Predicted nucleic-acid-binding protein (contains the HHH domain) 3 4 5 5 ---------------|-----|-----|--|---|--- 10 [T] COG1639 Predicted signal transduction protein 1 5 5 5 |||---||------------------------------ 6 [S] COG1693 Uncharacterized protein conserved in archaea 4 5 5 9 ---------------|-----|-||---------|--- 11 [S] COG1699 Uncharacterized protein conserved in bacteria 2 5 5 5 |||---|--------|---------------------- 5 [S] COG1751 Uncharacterized conserved protein 1 5 5 6 -||--|||------------------------------ 6 [S] COG1772 Uncharacterized protein conserved in archaea 5 5 5 6 ---------------|-||-----|---------|--- 6 [V] COG1787 Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes 3 5 5 5 ||-----|--------------|-|------------- 5 [S] COG1809 Uncharacterized conserved protein 1 5 5 5 |||---||------------------------------ 12 [S] COG1810 Uncharacterized protein conserved in archaea 2 5 5 6 |||--|--|----------------------------- 8 [S] COG1817 Uncharacterized protein conserved in archaea 1 5 5 5 |||---||------------------------------ 5 [R] COG1821 Predicted ATP-utilizing enzyme (ATP-grasp superfamily) 1 5 5 6 |||--|-|------------------------------ 6 [S] COG1844 Uncharacterized protein conserved in archaea 1 5 5 5 |||---||------------------------------ 7 [C] COG1880 CO dehydrogenase/acetyl-CoA synthase epsilon subunit 1 5 5 5 |||---||------------------------------ 5 [S] COG1891 Uncharacterized protein conserved in archaea 2 5 5 5 -||--||--------|---------------------- 6 [S] COG1895 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN 1 5 5 5 |||---||------------------------------ 9 [C] COG1908 Coenzyme F420-reducing hydrogenase, delta subunit 1 5 5 5 |||---||------------------------------ 5 [C] COG1927 Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin dehydrogenase 1 5 5 6 -||--|||------------------------------ 6 [S] COG1935 Uncharacterized conserved protein 4 5 5 10 ---------------|---|---||---|--------- 12 [K] COG1954 Glycerol-3-phosphate responsive antiterminator (mRNA-binding) 1 5 5 5 |||---||------------------------------ 6 [H] COG1962 Tetrahydromethanopterin S-methyltransferase, subunit H 1 5 5 5 |||---||------------------------------ 5 [J] COG2024 Phenylalanyl-tRNA synthetase alpha subunit (archaeal type) 1 5 5 6 |||--|-|------------------------------ 6 [S] COG2029 Uncharacterized conserved protein 1 5 5 5 |||---||------------------------------ 8 [C] COG2037 Formylmethanofuran:tetrahydromethanopterin formyltransferase 1 5 5 5 |||---||------------------------------ 14 [S] COG2043 Uncharacterized protein conserved in archaea 3 5 5 6 ---------------|||-----||------------- 6 [S] COG2052 Uncharacterized protein conserved in bacteria 1 5 5 5 |||---||------------------------------ 5 [R] COG2054 Uncharacterized archaeal kinase related to aspartokinases, uridylate kinases 1 5 5 5 |||---||------------------------------ 5 [E] COG2061 ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase 1 5 5 5 |||---||------------------------------ 6 [C] COG2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein) 1 5 5 6 ||---|||------------------------------ 6 [S] COG2083 Uncharacterized protein conserved in archaea 4 5 5 8 ------|------------|-|-||------------- 9 [M] COG2088 Uncharacterized protein, involved in the regulation of septum location 1 5 5 6 ||||-|-------------------------------- 6 [J] COG2117 Predicted subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain 2 5 5 5 |||----|---------|-------------------- 8 [R] COG2144 Selenophosphate synthetase-related proteins 4 5 5 10 --------------|-||----|-----|--------- 10 [S] COG2149 Predicted membrane protein 3 5 5 10 ---------------|-------||---|-------|- 11 [G] COG2160 L-arabinose isomerase 1 5 5 5 |||---||------------------------------ 10 [C] COG2218 Formylmethanofuran dehydrogenase subunit C 1 5 5 5 |||---||------------------------------ 5 [R] COG2232 Predicted ATP-dependent carboligase related to biotin carboxylase 3 4 5 6 -|---|--|-|----|---------------------- 7 [S] COG2245 Predicted membrane protein 4 5 5 9 -----|---------|||----|--------------- 9 [R] COG2251 Predicted nuclease (RecB family) 4 5 5 7 -----------------||----||---|--------- 33 [T] COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 4 5 5 9 -----------------||-----|--|--------|- 18 [S] COG2318 Uncharacterized protein conserved in bacteria 3 5 5 5 |--|------------|||------------------- 5 [S] COG2324 Predicted membrane protein 3 4 5 10 ---------------|--|----|||------------ 11 [R] COG2344 AT-rich DNA-binding protein 4 4 5 7 --|---------------|--|--||------------ 14 [V] COG2348 Uncharacterized protein involved in methicillin resistance 3 3 5 10 ------------------|-----|--||-|------- 10 [L] COG2356 Endonuclease I 4 5 5 7 ------------------|---|||------|------ 9 [S] COG2364 Predicted membrane protein 4 5 5 5 --|-----------|-|||------------------- 5 [R] COG2389 Uncharacterized metal-binding protein 3 5 5 6 -----|||--|-----------------|--------- 7 [R] COG2401 ABC-type ATPase fused to a predicted acetyltransferase domain 2 4 5 6 -----||||-|--------------------------- 10 [S] COG2411 Uncharacterized conserved protein 2 4 5 6 -----|||-||--------------------------- 7 [R] COG2413 Predicted nucleotidyltransferase 2 4 5 6 --|--||-|-|--------------------------- 7 [S] COG2430 Uncharacterized conserved protein 1 5 5 6 -|||-||------------------------------- 7 [S] COG2469 Uncharacterized conserved protein 5 5 5 7 ----|------------|----||----------|--- 9 [R] COG2605 Predicted kinase related to galactokinase and mevalonate kinase 2 3 5 12 -----------------------|----|-||--|--- 21 [R] COG2704 Anaerobic C4-dicarboxylate transporter 2 4 5 13 -----------------------||---|--|-|---- 13 [S] COG2707 Predicted membrane protein 3 5 5 6 -----------------|-----||--|----|----- 6 [R] COG2715 Uncharacterized membrane protein, required for spore maturation in B.subtilis. 1 2 5 9 ---------------------------||||----|-- 11 [E] COG2716 Glycine cleavage system regulatory protein 4 5 5 6 ------------------|---|||--|---------- 8 [V] COG2720 Uncharacterized vancomycin resistance protein 3 4 5 10 ----------------------||----||------|- 11 [S] COG2733 Predicted membrane protein 2 4 5 12 -------------------|---||||----------- 12 [S] COG2739 Uncharacterized protein conserved in bacteria 3 5 5 5 |-|---|--------|-------|-------------- 6 [R] COG2768 Uncharacterized Fe-S center protein 1 4 5 9 -------------------------------||||-|- 10 [S] COG2833 Uncharacterized protein conserved in bacteria 3 4 5 6 -----------------|---|------|-|---|--- 8 [S] COG2859 Uncharacterized protein conserved in bacteria 1 3 5 10 ---------------------------||---|||--- 12 [S] COG2879 Uncharacterized small protein 1 5 5 5 ||||--|------------------------------- 12 [S] COG2881 Uncharacterized protein conserved in archaea 4 5 5 9 ------------------|---|--|---|------|- 9 [S] COG2899 Uncharacterized protein conserved in bacteria 2 4 5 8 ----------------------|-------|--|-||- 9 [R] COG2907 Predicted NAD/FAD-binding protein 3 3 5 10 ----------------------||---||-|------- 13 [K] COG2909 ATP-dependent transcriptional regulator 1 1 5 11 ---------------------------|||||------ 11 [R] COG2915 Uncharacterized protein involved in purine metabolism 1 2 5 11 ----------------------------|||||----- 23 [R] COG2916 DNA-binding protein H-NS 3 5 5 5 -----------||--|-------------|--|----- 7 [S] COG2930 Uncharacterized conserved protein 3 3 5 10 ----------------|-|---------|-||------ 14 [S] COG2949 Uncharacterized membrane protein 2 5 5 8 ----------------||-----------|---|--|- 10 [S] COG2954 Uncharacterized protein conserved in bacteria 1 2 5 11 ----------------------------|-||||---- 11 [L] COG2965 Primosomal replication protein N 2 2 5 10 --------------------|-------||||------ 10 [K] COG2973 Trp operon repressor 2 3 5 14 ----------------------|----||-|-----|- 14 [Q] COG2977 Phosphopantetheinyl transferase component of siderophore synthetase 2 3 5 9 ----------------||---------||-|------- 9 [E] COG2988 Succinylglutamate desuccinylase 1 2 5 13 ----------------------------|-||---||- 17 [S] COG2989 Uncharacterized protein conserved in bacteria 1 2 5 7 ---------------------------||-||-|---- 8 [S] COG2991 Uncharacterized protein conserved in bacteria 2 4 5 5 -----------------|------------|-||--|- 6 [O] COG2994 ACP:hemolysin acyltransferase (hemolysin-activating protein) 1 2 5 11 ----------------------------|-||||---- 18 [S] COG2995 Uncharacterized paraquat-inducible protein A 3 5 5 5 |-------|---------------------|-|-|--- 5 [H] COG2998 ABC-type tungstate transport system, permease component 2 2 5 5 -----------------------|---||||------- 7 [S] COG3007 Uncharacterized paraquat-inducible protein B 1 2 5 10 ---------------------------||-|-||---- 10 [S] COG3009 Uncharacterized protein conserved in bacteria 1 2 5 10 ---------------------------||-|||----- 10 [T] COG3026 Negative regulator of sigma E activity 1 2 5 8 ---------------------------||-||-|---- 8 [S] COG3036 Uncharacterized protein conserved in bacteria 3 3 5 9 -------------------|----|--||-|------- 9 [E] COG3048 D-serine dehydratase 3 3 5 9 -------------------|-----|--|-||------ 10 [C] COG3051 Citrate lyase, alpha subunit 3 3 5 9 -------------------|-----|--|-||------ 10 [C] COG3052 Citrate lyase, gamma subunit 3 3 5 9 -------------------|-----|--|-||------ 10 [C] COG3053 Citrate lyase synthetase 2 3 5 10 -------------------|--------|-||----|- 13 [S] COG3055 Uncharacterized protein conserved in bacteria 2 3 5 10 --------------|------------||--|----|- 10 [O] COG3058 Uncharacterized protein involved in formate dehydrogenase formation 1 1 5 10 ---------------------------|||||------ 10 [S] COG3079 Uncharacterized protein conserved in bacteria 2 2 5 11 ------------------------|--||-||------ 15 [T] COG3103 SH3 domain protein 1 1 5 10 ---------------------------|||||------ 10 [R] COG3107 Putative lipoprotein 1 2 5 13 ----------------------------|-||---||- 19 [S] COG3108 Uncharacterized protein conserved in bacteria 1 1 5 10 ---------------------------|||||------ 10 [D] COG3115 Cell division protein 1 2 5 7 ---------------------------|||-----||- 7 [S] COG3128 Uncharacterized iron-regulated protein 1 2 5 8 ---------------------------||||-|----- 14 [P] COG3131 Periplasmic glucans biosynthesis protein 1 2 5 9 ---------------------------||||-|----- 9 [S] COG3147 Uncharacterized protein conserved in bacteria 1 2 5 9 ---------------------------||-|||----- 15 [R] COG3150 Predicted esterase 1 3 5 11 ---------------------------||-|-|---|- 11 [I] COG3154 Putative lipid carrier protein 1 3 5 10 ---------------------------||-|-|---|- 28 [S] COG3157 Hemolysin-coregulated protein (uncharacterized) 1 2 5 9 ---------------------------||||-|----- 9 [S] COG3164 Predicted membrane protein 1 2 5 6 ---------------------------|-||-||---- 6 [NU] COG3167 Tfp pilus assembly protein PilO 1 2 5 6 ---------------------------|-||-||---- 6 [NU] COG3168 Tfp pilus assembly protein PilP 2 3 5 6 ------------------|--------|-||-----|- 6 [S] COG3169 Uncharacterized protein conserved in bacteria 1 2 5 6 ---------------------------|-||-||---- 8 [NU] COG3170 Tfp pilus assembly protein FimV 3 3 5 11 ----------------------|--|-||--|------ 11 [H] COG3172 Predicted ATPase/kinase involved in NAD metabolism 2 3 5 5 ------------------|--------||--|----|- 8 [R] COG3179 Predicted chitinase 2 4 5 11 -----------||--------------||-------|- 13 [F] COG3194 Ureidoglycolate hydrolase 2 4 5 13 ----------------------|----|------|||- 15 [E] COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase 1 2 5 12 ----------------------------|-||||---- 67 [M] COG3203 Outer membrane protein (porin) 2 4 5 5 ---|-----------------------|--|--|-|-- 6 [S] COG3205 Predicted membrane protein 1 3 5 8 ---------------------------|--|-||--|- 12 [P] COG3213 Uncharacterized protein involved in response to NO 1 3 5 8 ---------------------------|-|----|||- 8 [R] COG3218 ABC-type uncharacterized transport system, auxiliary component 2 2 5 10 ------------------------||-||--|------ 10 [S] COG3223 Predicted membrane protein 2 4 5 9 ----------------||---------||---|----- 9 [S] COG3228 Uncharacterized protein conserved in bacteria 4 5 5 7 ------------------|---|--|-|--------|- 8 [J] COG3231 Aminoglycoside phosphotransferase 3 5 5 8 -|---|----------------|----|----|----- 8 [R] COG3233 Predicted deacetylase 4 4 5 5 ----------------|-|---|----||--------- 5 [S] COG3236 Uncharacterized protein conserved in bacteria 1 3 5 6 ---------------------------|--|-||-|-- 10 [C] COG3245 Cytochrome c5 3 5 5 15 ----|-------------------|---|-----|-|- 19 [S] COG3254 Uncharacterized conserved protein 2 5 5 5 -----------------|---------|----|-|-|- 7 [C] COG3258 Cytochrome c 3 4 5 10 -----||------------------|--|-|------- 10 [S] COG3270 Uncharacterized conserved protein 2 3 5 9 |-|------------------------||-|------- 9 [S] COG3272 Uncharacterized conserved protein 2 4 5 9 -------------------------|--|-|-|----| 10 [S] COG3274 Uncharacterized protein conserved in bacteria 3 4 5 10 -------------------|----|---|-|-----|- 13 [T] COG3275 Putative regulator of cell autolysis 2 4 5 6 -|---|-||-|--------------------------- 6 [S] COG3286 Uncharacterized protein conserved in archaea 3 3 5 9 ----------------------|-||--|-|------- 20 [T] COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism 3 4 5 5 -|-|----|-|-------|------------------- 5 [S] COG3294 Uncharacterized conserved protein 2 4 5 5 ------------------|----------||-|--|-- 5 [S] COG3295 Uncharacterized protein conserved in bacteria 4 5 5 5 ----------------|||-----|--|---------- 5 [S] COG3296 Uncharacterized protein conserved in bacteria 2 3 5 8 ------------------------|---||-|-|---- 13 [S] COG3299 Uncharacterized homolog of phage Mu protein gp47 3 3 5 9 ------|-||------------------|--|------ 10 [P] COG3301 Formate-dependent nitrite reductase, membrane component 2 3 5 11 ----------------------|-----|-||---|-- 11 [S] COG3304 Predicted membrane protein 1 3 5 11 ----------------------------|||-|---|- 25 [K] COG3311 Predicted transcriptional regulator 1 2 5 11 ---------------------------||-||-|---- 11 [C] COG3312 F0F1-type ATP synthase, subunit I 4 5 5 10 -------------------|--|||--|---------- 11 [S] COG3323 Uncharacterized protein conserved in bacteria 4 4 5 6 ---|-------|------------|---|-|------- 9 [G] COG3325 Chitinase 4 5 5 6 ---------|------------|-|---|-------|- 7 [K] COG3327 Phenylacetic acid-responsive transcriptional repressor 4 5 5 6 ----------------||----|-|----------|-- 7 [R] COG3329 Predicted permease 3 5 5 5 ---------------|||-----||------------- 6 [S] COG3330 Uncharacterized protein conserved in bacteria 3 4 5 11 --------------|---------|---------|||- 11 [S] COG3334 Uncharacterized conserved protein 3 5 5 5 -----------||--|-------||------------- 6 [R] COG3341 Predicted double-stranded RNA/RNA-DNA hybrid binding protein 3 3 5 5 ---------------|--------||--|-|------- 5 [G] COG3345 Alpha-galactosidase 4 5 5 8 ----|------------|------|---|-------|- 14 [S] COG3347 Uncharacterized conserved protein 2 5 5 6 |-||-------------------||------------- 6 [L] COG3359 Predicted exonuclease 3 5 5 6 ---|------------------|----|----|---|- 6 [S] COG3360 Uncharacterized conserved protein 1 5 5 5 |-||--||------------------------------ 5 [R] COG3364 Zn-ribbon containing protein 1 5 5 5 |-||--||------------------------------ 5 [S] COG3365 Uncharacterized protein conserved in archaea 1 5 5 5 -|||--||------------------------------ 12 [S] COG3366 Uncharacterized protein conserved in archaea 2 3 5 6 ----|-|-|||--------------------------- 8 [S] COG3370 Uncharacterized protein conserved in archaea 2 3 5 7 ----||--|||--------------------------- 12 [S] COG3371 Predicted membrane protein 3 4 5 6 ----|-|-||-----|---------------------- 8 [S] COG3374 Predicted membrane protein 3 5 5 5 ---|------------||---------|----|----- 5 [R] COG3380 Predicted NAD/FAD-dependent oxidoreductase 4 5 5 10 |---|----|--------------|-----------|- 12 [R] COG3383 Uncharacterized anaerobic dehydrogenase 1 5 5 6 --|||-||------------------------------ 6 [S] COG3388 Uncharacterized protein conserved in archaea 1 5 5 7 --|||||------------------------------- 9 [S] COG3390 Uncharacterized protein conserved in archaea 2 2 5 6 ------------------------||-||-|------- 7 [S] COG3397 Uncharacterized protein conserved in bacteria 2 4 5 6 ---||-|-||---------------------------- 35 [R] COG3413 Predicted DNA binding protein 1 3 5 5 ---------------------------|||--|---|- 5 [S] COG3416 Uncharacterized protein conserved in bacteria 2 4 5 7 --------|------------------|----||--|- 7 [P] COG3420 Nitrous oxidase accessory protein 4 5 5 7 ----|-----------|-|---------|----|---- 8 [V] COG3440 Predicted restriction endonuclease 2 4 5 9 ----------------||---------||-------|- 12 [T] COG3447 Predicted integral membrane sensor domain 3 4 5 7 ---------------||----------||-------|- 20 [R] COG3450 Predicted enzyme of the cupin superfamily 1 3 5 9 ---------------------------||-|-|---|- 16 [S] COG3455 Uncharacterized protein conserved in bacteria 3 5 5 5 ------------------|-----|---|---|---|- 5 [Q] COG3460 Uncharacterized enzyme of phenylacetate metabolism 4 5 5 5 -|-|-----------||-----|--------------- 6 [S] COG3472 Uncharacterized conserved protein 3 4 5 7 -----|---||---------------------|---|- 8 [Q] COG3473 Maleate cis-trans isomerase 2 3 5 9 -----------||----------------------||| 21 [C] COG3474 Cytochrome c2 3 4 5 5 -||----------------|----||------------ 5 [R] COG3478 Predicted nucleic-acid-binding protein containing a Zn-ribbon domain 2 4 5 5 ------------------|--------|----|--||- 6 [E] COG3483 Tryptophan 2,3-dioxygenase (vermilion) 3 3 5 7 -------------------|----||--|-|------- 8 [C] COG3493 Na+/citrate symporter 3 3 5 9 --------------|----|---------------||| 9 [S] COG3494 Uncharacterized protein conserved in bacteria 1 3 5 7 ---------------------------|||--|---|- 8 [R] COG3499 Phage protein U 4 4 5 9 ----------------|-|---|------------||- 9 [S] COG3502 Uncharacterized protein conserved in bacteria 2 4 5 10 ----------------------|----|----|--||- 12 [Q] COG3509 Poly(3-hydroxybutyrate) depolymerase 2 4 5 5 ------------------------||-----|-||--- 5 [S] COG3513 Uncharacterized protein conserved in bacteria 1 3 5 9 ---------------------------||-|-|---|- 22 [S] COG3515 Uncharacterized protein conserved in bacteria 1 3 5 9 ---------------------------||-|-|---|- 15 [S] COG3516 Uncharacterized protein conserved in bacteria 1 3 5 9 ---------------------------||-|-|---|- 16 [S] COG3517 Uncharacterized protein conserved in bacteria 1 3 5 9 ---------------------------||-|-|---|- 14 [S] COG3518 Uncharacterized protein conserved in bacteria 1 3 5 9 ---------------------------||-|-|---|- 13 [S] COG3519 Uncharacterized protein conserved in bacteria 1 3 5 9 ---------------------------||-|-|---|- 15 [S] COG3520 Uncharacterized protein conserved in bacteria 1 3 5 8 ---------------------------||-|-|---|- 12 [S] COG3521 Uncharacterized protein conserved in bacteria 1 3 5 9 ---------------------------||-|-|---|- 15 [S] COG3522 Uncharacterized protein conserved in bacteria 1 3 5 9 ---------------------------||-|-|---|- 15 [S] COG3523 Uncharacterized protein conserved in bacteria 2 3 5 7 -------------------------|---||----||- 8 [G] COG3525 N-acetyl-beta-hexosaminidase 3 4 5 8 --|--------------------|||----|------- 11 [Q] COG3527 Alpha-acetolactate decarboxylase 1 3 5 5 ---------------------------||-|-|---|- 8 [O] COG3531 Predicted protein-disulfide isomerase 3 4 5 9 ---------------|--------|---|------||- 10 [S] COG3533 Uncharacterized protein conserved in bacteria 3 4 5 8 ---------------|-------||----------||- 10 [G] COG3534 Alpha-L-arabinofuranosidase 3 5 5 7 |-|---|----------------|------------|- 7 [S] COG3543 Uncharacterized conserved protein 4 5 5 6 ----------------|||---|-------------|- 10 [S] COG3544 Uncharacterized protein conserved in bacteria 4 4 5 5 |-----------------|------|---------||- 11 [S] COG3548 Predicted integral membrane protein 2 3 5 6 ----------------|------------|||----|- 8 [R] COG3549 Plasmid maintenance system killer protein 4 5 5 7 |---------|-----------|---------|---|- 10 [R] COG3552 Protein containing von Willebrand factor type A (vWA) domain 3 5 5 7 -----------||-----|--------|--------|- 8 [L] COG3569 Topoisomerase IB 3 4 5 9 ----------------------|--|---|-----||- 9 [H] COG3572 Gamma-glutamylcysteine synthetase 3 4 5 7 ---------------|--|----|||------------ 15 [S] COG3584 Uncharacterized protein conserved in bacteria 2 4 5 7 --|-------------------------|--|--|-|- 7 [S] COG3586 Uncharacterized conserved protein 2 4 5 7 -------------------|--------|--|-||--- 8 [V] COG3587 Restriction endonuclease 4 5 5 10 --|-------------------|--|---|-----|-- 10 [O] COG3590 Predicted metalloendopeptidase 3 4 5 7 --|---------------------||--|-------|- 7 [S] COG3592 Uncharacterized conserved protein 3 4 5 8 -----|-----------------|||--|--------- 13 [S] COG3595 Uncharacterized conserved protein 4 5 5 5 ----------------|||------|--------|--- 5 [S] COG3597 Uncharacterized protein/domain associated with GTPases 3 4 5 10 -----|---------|-------|||------------ 10 [S] COG3601 Predicted membrane protein 1 2 5 12 ---------------------------||-|----||- 12 [T] COG3605 Signal transduction protein containing GAF and PtsI domains 3 4 5 5 -----------------||--------|--|-----|- 5 [T] COG3614 Predicted periplasmic ligand-binding sensor domain 1 4 5 8 ---------------------------||---|-|-|- 13 [R] COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold 1 5 5 7 --|||||------------------------------- 7 [K] COG3620 Predicted transcriptional regulator with C-terminal CBS domains 2 3 5 12 -------------------------||-|-||------ 14 [G] COG3623 Putative L-xylulose-5-phosphate 3-epimerase 5 5 5 8 ---------------|---|--|--|----------|- 14 [T] COG3629 DNA-binding transcriptional activator of the SARP family 1 5 5 5 |||---||------------------------------ 17 [D] COG3640 CO dehydrogenase maturation factor 4 4 5 6 ------------|-----|-----|----------||- 7 [S] COG3665 Uncharacterized conserved protein 4 5 5 5 ---------|-----|---------|---|-----|-- 7 [G] COG3669 Alpha-L-fucosidase 3 5 5 6 ----------------||----|---------|--|-- 12 [Q] COG3670 Lignostilbene-alpha,beta-dioxygenase and related enzymes 3 4 5 10 -------------------|-|------|--|----|- 10 [R] COG3683 ABC-type uncharacterized transport system, periplasmic component 2 4 5 8 ----------------||-----|||------------ 8 [R] COG3688 Predicted RNA-binding protein containing a PIN domain 2 4 5 8 ----------------||-----|||------------ 8 [S] COG3689 Predicted membrane protein 4 5 5 6 ----------------||||-----|------------ 7 [R] COG3694 ABC-type uncharacterized transport system, permease component 3 3 5 8 -------------------|-----|--|-||------ 9 [HI] COG3697 Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) 3 4 5 11 ----------------------|-|---|-|-----|- 32 [K] COG3710 DNA-binding winged-HTH domains 1 3 5 6 ---------------------------||---|--||- 24 [PT] COG3712 Fe2+-dicitrate sensor, membrane component 1 3 5 8 ----------------------------|---||-||- 8 [L] COG3727 DNA G:T-mismatch repair endonuclease 2 3 5 10 ------------------------||-||-------|- 16 [L] COG3728 Phage terminase, small subunit 3 4 5 8 ----------------|-------|--||------|-- 13 [R] COG3729 General stress protein 1 3 5 9 -----------------------------|--||-||- 9 [S] COG3737 Uncharacterized conserved protein 2 3 5 7 ------------------------||-----|---||- 7 [S] COG3739 Uncharacterized integral membrane protein 2 3 5 8 ------------------|--------||------||- 13 [E] COG3741 N-formylglutamate amidohydrolase 3 5 5 7 ----------------||----|----------|--|- 15 [S] COG3744 Uncharacterized protein conserved in bacteria 2 4 5 12 -----------------------|-|--||------|- 23 [M] COG3757 Lyzozyme M1 (1,4-beta-N-acetylmuramidase) 2 4 5 6 ---------------------|---------||--||- 6 [S] COG3762 Predicted membrane protein 2 4 5 9 ------------------------|---|---|--||- 10 [S] COG3766 Predicted membrane protein 2 4 5 5 -----------||--------------|-------||- 5 [S] COG3777 Uncharacterized conserved protein 2 5 5 8 ----------------||----------|---|---|- 8 [S] COG3781 Predicted membrane protein 3 4 5 10 ----------------------|||----------||- 10 [S] COG3786 Uncharacterized protein conserved in bacteria 3 5 5 8 --||------------||------------------|- 21 [C] COG3794 Plastocyanin 3 3 5 8 ----------------------|-||---------||- 10 [S] COG3797 Uncharacterized protein conserved in bacteria 2 5 5 6 -------------------------|--|---|-||-- 6 [S] COG3817 Predicted membrane protein 2 5 5 6 -------------------------|--|---|-||-- 6 [S] COG3819 Predicted membrane protein 4 5 5 5 ------------------|---|--|--|------|-- 5 [O] COG3823 Glutamine cyclotransferase 2 4 5 5 ----------------|----------|----|--||- 5 [S] COG3825 Uncharacterized protein conserved in bacteria 4 5 5 8 ----------------|-||--------|-------|- 16 [S] COG3831 Uncharacterized conserved protein 1 3 5 8 -----------------------------|--|--||| 13 [U] COG3838 Type IV secretory pathway, VirB2 components (pilins) 2 5 5 7 -------------------------|---|--|-|-|- 12 [U] COG3843 Type IV secretory pathway, VirD2 components (relaxase) 1 3 5 7 ---------------------------|---||--||- 16 [U] COG3847 Flp pilus assembly protein, pilin Flp 3 4 5 9 --|---------------|----|||------------ 11 [P] COG3853 Uncharacterized protein involved in tellurite resistance 4 5 5 5 --------------|---|----|---|----|----- 7 [S] COG3868 Uncharacterized conserved protein 4 5 5 7 ----------------|-|----||-----------|- 8 [R] COG3871 Uncharacterized stress protein (general stress protein 26) 2 4 5 11 -----------------|---------||---|---|- 11 [R] COG3895 Predicted periplasmic protein 2 4 5 8 -----------||--------------|-------||- 11 [R] COG3897 Predicted methyltransferase 3 5 5 5 --|-------------||-----||------------- 7 [S] COG3937 Uncharacterized conserved protein 3 3 5 5 --------|||------------|------|------- 6 [S] COG3945 Uncharacterized conserved protein 2 3 5 10 ---------------------|-----||-|-|----- 11 [MNO] COG3951 Rod binding protein 2 3 5 9 ------------------------||-||---|----- 12 [R] COG3969 Predicted phosphoadenosine phosphosulfate sulfotransferase 3 5 5 6 -|---------------------||---------||-- 6 [M] COG3980 Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase 2 5 5 5 |-|----|---||------------------------- 5 [S] COG4021 Uncharacterized conserved protein 2 4 5 6 ---||--||-|--------------------------- 6 [U] COG4023 Preprotein translocase subunit Sec61beta 2 3 5 5 ------|||||--------------------------- 5 [S] COG4034 Uncharacterized protein conserved in archaea 2 3 5 5 |------||||--------------------------- 5 [S] COG4046 Uncharacterized protein conserved in archaea 2 3 5 5 -|-----||||--------------------------- 6 [L] COG4080 RecB-family nuclease 2 4 5 6 |------|---------------|||------------ 6 [S] COG4086 Predicted secreted protein 2 4 5 5 --|---||||---------------------------- 5 [S] COG4089 Predicted membrane protein 4 5 5 6 -|--------------|--------||----------| 7 [S] COG4095 Uncharacterized conserved protein 4 5 5 8 --|-------------|--------|--|---|----- 12 [V] COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases 3 4 5 5 ----------------|------|-|-|--|------- 5 [P] COG4097 Predicted ferric reductase 3 4 5 12 ------------------|---|----||-------|- 12 [R] COG4106 Trans-aconitate methyltransferase 2 4 5 9 ----------------|----------||---|---|- 9 [C] COG4117 Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) 3 4 5 12 ----------------------||||----------|- 21 [S] COG4129 Predicted membrane protein 4 4 5 10 ------|------------|-|------|--|------ 10 [H] COG4145 Na+/panthothenate symporter 3 4 5 9 -||---------------------||---------|-- 9 [R] COG4152 ABC-type uncharacterized transport system, ATPase component 1 2 5 12 ---------------------------||-||----|- 26 [E] COG4160 ABC-type arginine/histidine transport system, permease component 4 5 5 6 ----------------|-----||-------|----|- 6 [S] COG4185 Uncharacterized protein conserved in bacteria 4 5 5 5 ----|----|------------|||------------- 6 [R] COG4194 Predicted membrane protein 3 3 5 10 -------------------|-|------|-||------ 10 [G] COG4211 ABC-type glucose/galactose transport system, permease component 1 2 5 12 ---------------------------||-||----|- 26 [E] COG4215 ABC-type arginine transport system, permease component 3 4 5 5 -----------||-|------------|-|-------- 5 [C] COG4229 Predicted enolase-phosphatase 3 5 5 6 --------------|-||---------|--------|- 10 [S] COG4244 Predicted membrane protein 3 5 5 5 ----------------|||--------|--------|- 7 [T] COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase) 2 5 5 5 -----------||--------------|----|---|- 5 [F] COG4266 Allantoicase 4 5 5 5 ---------------|---|---|---|----|----- 5 [S] COG4267 Predicted membrane protein 4 5 5 6 --|---------------|------|--|-----|--- 6 [V] COG4268 McrBC 5-methylcytosine restriction system component 3 5 5 5 --|-----------------------|--|--|--|-- 5 [K] COG4271 Predicted nucleotide-binding protein containing TIR -like domain 4 4 5 5 |------------------|---|-----------||- 5 [R] COG4277 Predicted DNA-binding protein with the Helix-hairpin-helix motif 4 5 5 7 --|------|------||----|--------------- 8 [S] COG4279 Uncharacterized conserved protein 4 4 5 6 -----------|-------|----||-----|------ 7 [S] COG4283 Uncharacterized conserved protein 4 5 5 6 -----------|||------|---------------|- 7 [S] COG4286 Uncharacterized conserved protein related to MYG1 family 4 4 5 8 ----------------|-----|-||-------|---- 8 [P] COG4300 Predicted permease, cadmium resistance protein 4 5 5 6 ------------|---||----|---------|----- 6 [S] COG4301 Uncharacterized conserved protein 3 5 5 6 ----------------|-------|--|----|---|- 10 [S] COG4319 Ketosteroid isomerase homolog 4 5 5 5 ------------|---------|-|--|--------|- 5 [S] COG4336 Uncharacterized conserved protein 1 3 5 5 ---------------------------|||--|---|- 7 [R] COG4385 Bacteriophage P2-related tail formation protein 3 3 5 5 ----------------------|--|--|-||------ 7 [G] COG4409 Neuraminidase (sialidase) 4 4 5 9 ------------------|---|--|---------||- 10 [S] COG4420 Predicted membrane protein 3 4 5 7 ----------|-----|----------|--|-----|- 10 [P] COG4454 Uncharacterized copper-binding protein 1 2 5 12 ---------------------------||-||----|- 12 [P] COG4531 ABC-type Zn2+ transport system, periplasmic component/surface adhesin 4 4 5 6 ----------------|--|--|-||------------ 6 [R] COG4552 Predicted acetyltransferase involved in intracellular survival and related acetyltransferases 3 3 5 9 ----------------------|-||--|-|------- 19 [KT] COG4565 Response regulator of citrate/malate metabolism 1 3 5 8 ---------------------------|-|--|--||- 10 [TK] COG4567 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain 4 5 5 8 ----------------||-|----|---|--------- 10 [QC] COG4576 Carbon dioxide concentrating mechanism/carboxysome shell protein 4 5 5 8 ----------------||-|----|---|--------- 31 [QC] COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein 3 4 5 11 ----------------------|-|---|--|----|- 11 [K] COG4578 Glucitol operon activator 4 5 5 6 ----------------||||-----|------------ 7 [R] COG4587 ABC-type uncharacterized transport system, permease component 4 5 5 5 -----------|||-|-------|-------------- 8 [R] COG4624 Iron only hydrogenase large subunit, C-terminal domain 2 4 5 6 -------------------|-------|-|--|---|- 11 [S] COG4625 Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain 2 4 5 8 -----------------------|||--|-------|- 19 [R] COG4626 Phage terminase-like protein, large subunit 2 4 5 8 ------------------|--------|----|--||- 9 [F] COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B 4 5 5 5 --------------|-|||----------------|-- 105 [S] COG4636 Uncharacterized protein conserved in cyanobacteria 5 5 5 5 ----------------|-||---|----------|--- 7 [R] COG4639 Predicted kinase 3 5 5 7 -----------------|-------|-|-----|--|- 7 [S] COG4642 Uncharacterized protein conserved in bacteria 2 4 5 8 ----------------------|-----|---|--||- 12 [R] COG4653 Predicted phage phi-C31 gp36 major capsid-like protein 3 5 5 5 |-------|---------------------|-|-|--- 5 [H] COG4662 ABC-type tungstate transport system, periplasmic component 2 4 5 9 --------------------|------||---|---|- 13 [U] COG4669 Type III secretory pathway, lipoprotein EscJ 3 3 5 8 ----------------|--------|--||-|------ 11 [S] COG4679 Phage-related protein 4 5 5 6 ---|--|-------|-|-------------------|- 6 [S] COG4711 Predicted membrane protein 3 4 5 5 ---|--|-----------------|--|---|------ 5 [S] COG4729 Uncharacterized conserved protein 2 4 5 10 ---------------------|----------|-|||- 14 [S] COG4731 Uncharacterized protein conserved in bacteria 2 4 5 8 ----------------|-----------|---||--|- 9 [S] COG4737 Uncharacterized protein conserved in bacteria 5 5 5 5 --|-------------|----||-|------------- 5 [S] COG4748 Uncharacterized conserved protein 3 4 5 6 ----|---||-------------------|--|----- 6 [S] COG4754 Uncharacterized conserved protein 4 4 5 5 ---------------|---|-|--||------------ 5 [S] COG4769 Predicted membrane protein 1 3 5 9 ---------------------------||-|---|-|- 19 [P] COG4771 Outer membrane receptor for ferrienterochelin and colicins 1 3 5 6 ---------------------------||-----|||- 11 [P] COG4772 Outer membrane receptor for Fe3+-dicitrate 2 3 5 9 ----------------------|----||-|-----|- 10 [P] COG4779 ABC-type enterobactin transport system, permease component 2 4 5 9 --------------------|------||---|---|- 13 [U] COG4789 Type III secretory pathway, component EscV 2 4 5 9 --------------------|------||---|---|- 15 [U] COG4791 Type III secretory pathway, component EscT 2 4 5 9 --------------------|------||---|---|- 13 [U] COG4794 Type III secretory pathway, component EscS 2 5 5 5 |-|---|---------||-------------------- 6 [C] COG4802 Ferredoxin-thioredoxin reductase, catalytic subunit 3 5 5 8 --|----------------|--------|---|----| 13 [S] COG4804 Uncharacterized conserved protein 3 4 5 5 --------||-|||------------------------ 7 [J] COG4830 Ribosomal protein S26 4 5 5 5 --|---|------------|---|-----|-------- 9 [O] COG4870 Cysteine protease 4 4 5 5 -------||-|---------------|---------|- 6 [S] COG4933 Uncharacterized conserved protein 4 5 5 5 --|--------||---|-------------|------- 8 [O] COG4935 Regulatory P domain of the subtilisin-like proprotein convertases and other proteases 1 2 5 6 ---------------------------|-||-||---- 12 [NU] COG4968 Tfp pilus assembly protein PilE 1 3 5 9 ---------------------------||---|--||- 45 [K] COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain 3 4 5 6 ----|---||-------------------|--|----- 6 [P] COG4986 ABC-type anion transport system, duplicated permease component 1 2 5 6 ---------------------------|-||-||---- 8 [NU] COG5008 Tfp pilus assembly protein, ATPase PilU 3 5 5 6 |-|---|------------|----------------|- 21 [R] COG5012 Predicted cobalamin binding protein 2 4 5 5 |--|--|-||---------------------------- 5 [R] COG5258 GTPase 3 5 5 6 --|----------------|-----------|-|--|- 8 [P] COG5266 ABC-type Co2+ transport system, periplasmic component 2 5 5 6 -||--|-||----------------------------- 6 [J] COG5270 PUA domain (predicted RNA-binding domain) 3 5 5 5 -----------||----|-----|-|------------ 6 [D] COG5279 Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain 2 3 5 7 -----------------------|||--||-------- 9 [S] COG5283 Phage-related tail protein 4 5 5 7 -----------|----|-----|---------|---|- 9 [Q] COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin 4 5 5 8 -----|----------||----|-----|--------- 13 [S] COG5305 Predicted membrane protein 2 3 5 11 ------------------|---------|-||-|---- 14 [S] COG5339 Uncharacterized protein conserved in bacteria 3 4 5 6 --|---------------------|-------|--||- 17 [S] COG5361 Uncharacterized conserved protein 1 3 5 6 ---------------------------||---|---|| 19 [S] COG5430 Uncharacterized secreted protein 3 4 5 5 -------------------|--||||------------ 10 [S] COG5438 Predicted multitransmembrane protein 1 3 5 6 ----------------------------|---|--||| 9 [S] COG5510 Predicted small secreted protein 4 5 5 8 ---------------||||---|--------------- 8 [R] COG5512 Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives 3 4 5 8 ----------------|-------|---||--|----- 24 [R] COG5525 Bacteriophage tail assembly protein 4 5 5 5 -----------|||--|------|-------------- 7 [S] COG5542 Predicted integral membrane protein 3 4 5 10 ---------------|-------||--||--------- 10 [M] COG5581 Predicted glycosyltransferase 4 5 5 6 --|---|---------------|-|----------|-- 9 [S] COG5658 Predicted integral membrane protein