y a o g oooooooooooooooooooooooooooooooooooooo 1 3 3 9 ----------------------------|-----|-|- 9 [I] COG1133 ABC-type long-chain fatty acid transport system, fused permease and ATPase components 3 3 3 4 -|------------|---------|------------- 4 [H] COG1424 Pimeloyl-CoA synthetase 1 1 3 8 ----------------------------|-||------ 8 [H] COG1441 O-succinylbenzoate synthase 3 3 3 6 --------------||------|--------------- 6 [S] COG1507 Uncharacterized conserved protein 3 3 3 6 ---------------|-----|--|------------- 9 [R] COG1647 Esterase/lipase 3 3 3 4 ---------------|-----|-|-------------- 4 [S] COG1655 Uncharacterized protein conserved in bacteria 3 3 3 4 --------------||------|--------------- 4 [S] COG1659 Uncharacterized protein, linocin/CFP29 homolog 1 3 3 4 |----||------------------------------- 4 [S] COG1689 Uncharacterized protein conserved in archaea 2 3 3 3 |----|--------|----------------------- 3 [S] COG1700 Uncharacterized conserved protein 1 3 3 4 ||---|-------------------------------- 4 [S] COG1710 Uncharacterized protein conserved in archaea 3 3 3 4 ------------------|-|--|-------------- 4 [R] COG1768 Predicted phosphohydrolase 3 3 3 3 ------|-------||---------------------- 3 [L] COG1769 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) 1 3 3 4 ||---|-------------------------------- 4 [S] COG1771 Uncharacterized protein conserved in archaea 1 3 3 3 -|---||------------------------------- 6 [R] COG1800 Predicted transglutaminase-like proteases 1 3 3 4 ||---|-------------------------------- 8 [S] COG1822 Predicted archaeal membrane protein 2 3 3 4 -|---|--------|----------------------- 4 [S] COG1851 Uncharacterized conserved protein 2 3 3 8 --------------|-------------|-----|--- 9 [C] COG1969 Ni,Fe-hydrogenase I cytochrome b subunit 1 3 3 4 -|---||------------------------------- 4 [S] COG2028 Uncharacterized conserved protein 2 3 3 10 ----------------------|-----|-----|--- 10 [I] COG2134 CDP-diacylglycerol pyrophosphatase 3 3 3 4 --------------||------------------|--- 5 [O] COG2143 Thioredoxin-related protein 2 3 3 3 |-----|--------|---------------------- 3 [S] COG2164 Uncharacterized conserved protein 2 3 3 4 -|---|------------------|------------- 9 [M] COG2247 Putative cell wall-binding domain 2 3 3 5 ---|-|----------------|--------------- 9 [S] COG2253 Uncharacterized conserved protein 3 3 3 3 ------|--------|--|------------------- 3 [R] COG2316 Predicted hydrolase (HD superfamily) 3 3 3 3 --------------||--|------------------- 3 [S] COG2380 Uncharacterized protein conserved in bacteria 1 3 3 4 ||---|-------------------------------- 4 [S] COG2456 Uncharacterized conserved protein 3 3 3 5 ---------------------|-|----------|--- 17 [S] COG2604 Uncharacterized protein conserved in bacteria 3 3 3 4 -----|----|-------|------------------- 4 [V] COG2810 Predicted type IV restriction endonuclease 2 3 3 9 ------------------------|---|----|---- 9 [P] COG2822 Predicted periplasmic lipoprotein involved in iron transport 1 3 3 5 -------------------------------|-||--- 5 [S] COG2830 Uncharacterized protein conserved in bacteria 3 3 3 4 --------------|---------|-----|------- 4 [S] COG3002 Uncharacterized protein conserved in bacteria 1 1 3 8 ----------------------------|-||------ 8 [D] COG3006 Uncharacterized protein involved in chromosome partitioning 2 2 3 6 ---------------------|------|-|------- 6 [MP] COG3015 Uncharacterized lipoprotein NlpE involved in copper resistance 2 2 3 3 --------------|-------------|-|------- 4 [U] COG3031 Type II secretory pathway, component PulC 1 1 3 8 ----------------------------|-||------ 8 [L] COG3050 DNA polymerase III, psi subunit 1 1 3 8 ----------------------------|-||------ 8 [R] COG3054 Predicted transcriptional regulator 1 1 3 8 ----------------------------|-||------ 8 [M] COG3056 Uncharacterized lipoprotein 1 1 3 8 ----------------------------|-||------ 8 [L] COG3057 Negative regulator of replication initiationR 1 1 3 8 ----------------------------|-||------ 8 [KE] COG3060 Transcriptional regulator of met regulon 1 1 3 8 ----------------------------|-||------ 8 [M] COG3061 Cell envelope opacity-associated protein A 1 1 3 8 ----------------------------|-||------ 8 [M] COG3064 Membrane protein involved in colicin uptake 1 1 3 8 ----------------------------|-||------ 8 [L] COG3066 DNA mismatch repair protein 1 1 3 8 ----------------------------|-||------ 8 [S] COG3068 Uncharacterized protein conserved in bacteria 1 1 3 7 ----------------------------|-||------ 13 [C] COG3069 C4-dicarboxylate transporter 1 1 3 8 ----------------------------|-||------ 8 [S] COG3074 Uncharacterized protein conserved in bacteria 1 1 3 8 ----------------------------|-||------ 8 [S] COG3076 Uncharacterized protein conserved in bacteria 1 1 3 8 ----------------------------|-||------ 8 [S] COG3078 Uncharacterized protein conserved in bacteria 1 1 3 8 ----------------------------|-||------ 8 [S] COG3082 Uncharacterized protein conserved in bacteria 1 1 3 8 ----------------------------|-||------ 8 [S] COG3084 Uncharacterized protein conserved in bacteria 1 1 3 8 ----------------------------|-||------ 8 [S] COG3085 Uncharacterized protein conserved in bacteria 1 1 3 8 ----------------------------|-||------ 8 [S] COG3092 Uncharacterized protein conserved in bacteria 1 1 3 8 ----------------------------|-||------ 8 [D] COG3095 Uncharacterized protein involved in chromosome partitioning 1 1 3 8 ----------------------------|-||------ 8 [D] COG3096 Uncharacterized protein involved in chromosome partitioning 1 1 3 8 ----------------------------|-||------ 8 [S] COG3097 Uncharacterized protein conserved in bacteria 1 1 3 8 ----------------------------|-||------ 8 [S] COG3099 Uncharacterized protein conserved in bacteria 1 1 3 8 ----------------------------|-||------ 8 [S] COG3101 Uncharacterized protein conserved in bacteria 1 1 3 8 ----------------------------|-||------ 9 [S] COG3102 Uncharacterized protein conserved in bacteria 1 1 3 8 ----------------------------|-||------ 9 [S] COG3110 Uncharacterized protein conserved in bacteria 1 1 3 8 ----------------------------|-||------ 8 [S] COG3112 Uncharacterized protein conserved in bacteria 1 1 3 8 ----------------------------|-||------ 8 [S] COG3120 Uncharacterized protein conserved in bacteria 1 1 3 7 ---------------------------|||-------- 7 [S] COG3122 Uncharacterized protein conserved in bacteria 1 1 3 7 ---------------------------||-|------- 7 [S] COG3124 Uncharacterized protein conserved in bacteria 1 1 3 7 ---------------------------||-|------- 7 [J] COG3130 Ribosome modulation factor 1 1 3 7 ---------------------------|||-------- 7 [S] COG3134 Predicted outer membrane lipoprotein 1 1 3 7 ----------------------------|||------- 7 [M] COG3137 Putative salt-induced outer membrane protein 1 1 3 7 ---------------------------||-|------- 7 [S] COG3139 Uncharacterized protein conserved in bacteria 1 1 3 8 ----------------------------|-||------ 8 [S] COG3140 Uncharacterized protein conserved in bacteria 1 1 3 7 ---------------------------||-|------- 7 [S] COG3141 Uncharacterized protein conserved in bacteria 1 1 3 7 ---------------------------||-|------- 10 [S] COG3148 Uncharacterized conserved protein 1 1 3 7 ---------------------------||-|------- 7 [Q] COG3155 Uncharacterized protein involved in an early stage of isoprenoid biosynthesis 1 1 3 7 ---------------------------||-|------- 7 [K] COG3160 Regulator of sigma D 2 2 3 4 ----------------------|----||--------- 4 [S] COG3196 Uncharacterized protein conserved in bacteria 1 2 3 4 ---------------------------|--|--|---- 4 [S] COG3198 Uncharacterized protein conserved in bacteria 2 2 3 6 -----------------|---------||--------- 12 [S] COG3204 Uncharacterized protein conserved in bacteria 2 2 3 3 -----------|---------------|--|------- 3 [Q] COG3207 Pyoverdine/dityrosine biosynthesis protein 1 2 3 5 ---------------------------|---|-|---- 6 [S] COG3219 Uncharacterized protein conserved in bacteria 2 2 3 7 ----------------------|----||--------- 9 [S] COG3226 Uncharacterized protein conserved in bacteria 1 2 3 4 ---------------------------|--|--|---- 4 [S] COG3235 Predicted membrane protein 1 2 3 4 ---------------------------|-|---|---- 4 [C] COG3241 Azurin 1 1 3 6 ---------------------------||-|------- 6 [M] COG3248 Nucleoside-binding outer membrane protein 1 1 3 7 ---------------------------||-|------- 8 [S] COG3266 Uncharacterized protein conserved in bacteria 1 2 3 7 ----------------------------|--|--|--- 7 [P] COG3303 Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit 2 2 3 4 ----------------------|------||------- 4 [S] COG3305 Predicted membrane protein 1 2 3 11 ------------------------|||----------- 13 [R] COG3331 Penicillin-binding protein-related factor A, putative recombinase 3 3 3 3 ------|-------|---------|------------- 3 [L] COG3337 Uncharacterized protein predicted to be involved in DNA repair 1 2 3 10 ------------------------|||----------- 10 [K] COG3343 DNA-directed RNA polymerase, delta subunit 3 3 3 4 ---|------------------|-|------------- 4 [S] COG3361 Uncharacterized conserved protein 1 3 3 5 -|--||-------------------------------- 5 [S] COG3373 Uncharacterized protein conserved in archaea 3 3 3 4 ----|-----|-------|------------------- 5 [S] COG3375 Uncharacterized conserved protein 3 3 3 5 -------------------|----|---------|--- 6 [L] COG3392 Adenine-specific DNA methylase 3 3 3 7 ---|------------------|-|------------- 7 [S] COG3402 Uncharacterized conserved protein 3 3 3 3 ---|--------------|-----|------------- 4 [S] COG3403 Uncharacterized conserved protein 1 2 3 10 ----------------------------|-|---|--- 10 [R] COG3417 Collagen-binding surface adhesin SpaP (antigen I/II family) 1 1 3 8 ---------------------------||-|------- 8 [NUO] COG3418 Flagellar biosynthesis/type III secretory pathway chaperone 1 2 3 8 ----------------------------|--|-|---- 11 [K] COG3423 Predicted transcriptional regulator 3 3 3 5 ------------------|---|-|------------- 10 [Q] COG3424 Predicted naringenin-chalcone synthase 3 3 3 8 ---|------------------|-|------------- 8 [S] COG3428 Predicted membrane protein 3 3 3 3 --------------|---------|-----|------- 6 [T] COG3434 Predicted signal transduction protein containing EAL and modified HD-GYP domains 1 1 3 8 ----------------------------|-||------ 8 [R] COG3445 Acid-induced glycyl radical enzyme 3 3 3 4 ----|----------|--------------------|- 4 [S] COG3461 Uncharacterized conserved protein 2 3 3 4 ---||----------|---------------------- 5 [S] COG3462 Predicted membrane protein 2 3 3 5 ----||-----------|-------------------- 7 [S] COG3463 Predicted membrane protein 2 3 3 5 ----|-|-----------------|------------- 5 [S] COG3465 Uncharacterized conserved protein 1 3 3 3 -|--|-|------------------------------- 9 [S] COG3466 Putative transposon-encoded protein 2 2 3 3 ------------------------||----|------- 3 [Q] COG3479 Phenolic acid decarboxylase 2 2 3 10 ----------------------|-||------------ 11 [T] COG3480 Predicted secreted protein containing a PDZ domain 1 2 3 5 ---------------------------|--|-----|- 5 [P] COG3487 Uncharacterized iron-regulated protein 1 2 3 5 ---------------------------|--|-----|- 5 [C] COG3488 Predicted thiol oxidoreductase 1 2 3 5 ---------------------------|--|-----|- 5 [R] COG3489 Predicted periplasmic lipoprotein 1 2 3 5 ---------------------------|--|-----|- 5 [S] COG3490 Uncharacterized protein conserved in bacteria 1 2 3 3 ---------------------------|--|-----|- 4 [S] COG3495 Uncharacterized protein conserved in bacteria 3 3 3 6 -----------------|----|-------------|- 6 [V] COG3510 Cephalosporin hydroxylase 1 2 3 6 ---------------------------|--|-----|- 6 [O] COG3526 Uncharacterized protein conserved in bacteria 1 2 3 6 ----------------------------|-|---|--- 6 [S] COG3528 Uncharacterized protein conserved in bacteria 1 1 3 5 ---------------------------||-|------- 5 [R] COG3529 Predicted nucleic-acid-binding protein containing a Zn-ribbon domain 1 1 3 7 ---------------------------|||-------- 134 [NU] COG3539 P pilus assembly protein, pilin FimA 2 3 3 3 ------------------------|--|--------|- 3 [S] COG3551 Uncharacterized protein conserved in bacteria 2 3 3 5 ----------------------|----|--------|- 6 [S] COG3554 Uncharacterized protein conserved in bacteria 1 2 3 9 ------------------------|||----------- 9 [J] COG3557 Uncharacterized domain/protein associated with RNAses G and E 2 3 3 4 -----------------|---------|--------|- 4 [S] COG3558 Uncharacterized protein conserved in bacteria 2 2 3 5 ----------------------|-||------------ 5 [M] COG3559 Putative exporter of polyketide antibiotics 3 3 3 6 ----------------------|-|-----------|- 6 [S] COG3564 Uncharacterized protein conserved in bacteria 2 3 3 4 -----------------|---------|--------|- 4 [R] COG3565 Predicted dioxygenase of extradiol dioxygenase family 2 3 3 5 ------------------|--------|--------|- 5 [V] COG3570 Streptomycin 6-kinase 2 3 3 5 ----------------------|----|--------|- 5 [R] COG3571 Predicted hydrolase of the alpha/beta-hydrolase fold 3 3 3 6 ------------------|---|-------------|- 6 [R] COG3573 Predicted oxidoreductase 2 3 3 8 ----------------------|||------------- 8 [S] COG3583 Uncharacterized protein conserved in bacteria 1 2 3 10 ------------------------|||----------- 10 [L] COG3611 Replication initiation/membrane attachment protein 2 2 3 8 ------------------------||--|--------- 13 [S] COG3645 Uncharacterized phage-encoded protein 1 1 3 5 ----------------------------|-||------ 5 [S] COG3647 Predicted membrane protein 3 3 3 4 ------------|-----|-----|------------- 4 [Q] COG3648 Uricase (urate oxidase) 2 2 3 3 ---------------|--------||------------ 3 [L] COG3649 Uncharacterized protein predicted to be involved in DNA repair 2 3 3 3 ------------------|----------|-----|-- 3 [S] COG3656 Predicted periplasmic protein 3 3 3 3 ---------------|--------|----------|-- 3 [G] COG3661 Alpha-glucuronidase 2 3 3 3 -----------|---------------|-------|-- 3 [S] COG3673 Uncharacterized conserved protein 3 3 3 3 -----------|-----|------------|------- 4 [I] COG3675 Predicted lipase 2 3 3 4 ---|---------------------------|-|---- 30 [L] COG3676 Transposase and inactivated derivatives 2 3 3 5 ------------------|---------|----|---- 5 [S] COG3680 Uncharacterized protein conserved in bacteria 1 1 3 8 ----------------------------|-||------ 12 [S] COG3691 Uncharacterized protein conserved in bacteria 2 3 3 8 ------------------|---------|-------|- 8 [S] COG3698 Predicted periplasmic protein 2 2 3 6 -------------------------|--|--|------ 6 [R] COG3700 Acid phosphatase (class B) 1 2 3 9 ---------------------------||-------|- 11 [P] COG3709 Uncharacterized component of phosphonate metabolism 1 1 3 7 ----------------------------|-||------ 10 [K] COG3722 Transcriptional regulator 2 2 3 9 ------------------------||--|--------- 10 [L] COG3723 Recombinational DNA repair protein (RecE pathway) 1 2 3 7 ---------------------------||------|-- 8 [E] COG3724 Succinylarginine dihydrolase 1 1 3 7 ---------------------------|||-------- 7 [V] COG3725 Membrane protein required for beta-lactamase induction 2 2 3 5 ----------------------|------------||- 15 [S] COG3742 Uncharacterized protein conserved in bacteria 2 2 3 6 ---|-------------------------------||- 10 [S] COG3743 Uncharacterized conserved protein 1 2 3 3 ---------------------------|-|-----|-- 5 [P] COG3746 Phosphate-selective porin 1 1 3 7 -----------------------------------||| 8 [S] COG3750 Uncharacterized protein conserved in bacteria 2 2 3 5 -------------------------|---------||- 8 [M] COG3754 Lipopolysaccharide biosynthesis protein 1 2 3 3 ----------------------------||------|- 6 [S] COG3756 Uncharacterized protein conserved in bacteria 1 1 3 7 -----------------------------------||| 7 [C] COG3761 NADH:ubiquinone oxidoreductase 17.2 kD subunit 1 2 3 11 ------------------------|||----------- 11 [S] COG3763 Uncharacterized protein conserved in bacteria 1 1 3 8 ---------------------------||--|------ 19 [M] COG3765 Chain length determinant protein 1 2 3 5 ---------------------------|---|-|---- 6 [S] COG3767 Uncharacterized low-complexity protein 1 2 3 11 ----------------------------|--|----|- 11 [S] COG3768 Predicted membrane protein 3 3 3 7 -----|----|-----------------|--------- 7 [R] COG3769 Predicted hydrolase (HAD superfamily) 1 2 3 11 ----------------------------|--|----|- 11 [M] COG3770 Murein endopeptidase 1 1 3 8 ----------------------------|-||------ 8 [S] COG3771 Predicted membrane protein 1 1 3 7 ---------------------------||-|------- 8 [S] COG3776 Predicted membrane protein 1 2 3 6 ----------------------------|--|-|---- 7 [S] COG3778 Uncharacterized protein conserved in bacteria 1 3 3 4 ----------------------------|----|--|- 5 [S] COG3779 Uncharacterized protein conserved in bacteria 1 2 3 4 ---------------------------|--|--|---- 4 [S] COG3782 Uncharacterized protein conserved in bacteria 1 1 3 7 ----------------------------|-||------ 8 [C] COG3783 Soluble cytochrome b562 1 2 3 7 ---------------------------||------|-- 7 [S] COG3784 Uncharacterized protein conserved in bacteria 1 2 3 10 ----------------------------|------||- 10 [S] COG3785 Uncharacterized conserved protein 1 2 3 7 ----------------------------|--|--|--- 7 [S] COG3787 Uncharacterized protein conserved in bacteria 1 2 3 6 ---------------------------||------|-- 6 [S] COG3789 Uncharacterized protein conserved in bacteria 1 1 3 7 ----------------------------|-||------ 7 [S] COG3790 Predicted membrane protein 1 2 3 3 -----------------------------|-|-|---- 17 [S] COG3792 Uncharacterized protein conserved in bacteria 2 2 3 3 ------------------|----------------||- 4 [S] COG3798 Uncharacterized protein conserved in bacteria 2 3 3 4 ---|------------------------|-------|- 5 [E] COG3799 Methylaspartate ammonia-lyase 2 2 3 8 ----------------------|------------||- 14 [R] COG3800 Predicted transcriptional regulator 2 2 3 4 ----------------------|------------||- 5 [S] COG3801 Uncharacterized protein conserved in bacteria 1 2 3 6 ---------------------------|-------||- 7 [S] COG3802 Uncharacterized protein conserved in bacteria 3 3 3 4 ------|---------------|-------------|- 6 [S] COG3804 Uncharacterized conserved protein related to dihydrodipicolinate reductase 2 3 3 3 ----------------|-------------|-----|- 3 [Q] COG3805 Aromatic ring-cleaving dioxygenase 1 1 3 7 -----------------------------------||| 7 [S] COG3807 Uncharacterized protein conserved in bacteria 1 1 3 7 -----------------------------------||| 7 [S] COG3814 Uncharacterized protein conserved in bacteria 1 3 3 3 ||-|---------------------------------- 3 [S] COG3815 Predicted membrane protein 1 2 3 6 ---------------------------|-------||- 6 [S] COG3816 Uncharacterized protein conserved in bacteria 1 2 3 3 -----------------------------|-----||- 3 [R] COG3818 Predicted acetyltransferase, GNAT superfamily 1 1 3 7 -----------------------------------||| 7 [S] COG3820 Uncharacterized protein conserved in bacteria 1 2 3 5 ---------------------------|-------||- 5 [S] COG3821 Predicted membrane protein 2 2 3 7 ----------------------|------------||- 7 [S] COG3824 Uncharacterized protein conserved in bacteria 1 1 3 7 -----------------------------------||| 7 [S] COG3827 Uncharacterized protein conserved in bacteria 2 2 3 5 ------------------------|----------||- 5 [S] COG3828 Uncharacterized protein conserved in bacteria 1 1 3 6 ----------------------------|-||------ 8 [T] COG3851 Signal transduction histidine kinase, glucose-6-phosphate specific 2 3 3 5 ----------------------|||------------- 5 [S] COG3856 Uncharacterized conserved protein (small basic protein) 1 2 3 8 -----------------------|||------------ 8 [L] COG3857 ATP-dependent nuclease, subunit B 2 3 3 4 -----------------------||----|-------- 10 [R] COG3858 Predicted glycosyl hydrolase 1 2 3 6 -----------------------|||------------ 6 [S] COG3859 Predicted membrane protein 2 3 3 3 ------|----------------||------------- 3 [S] COG3863 Uncharacterized distant relative of cell wall-associated hydrolases 3 3 3 3 ---------------|--|----|-------------- 3 [S] COG3864 Uncharacterized protein conserved in bacteria 2 3 3 4 ---------------|-------||------------- 6 [G] COG3866 Pectate lyase 2 3 3 7 --------------------|--||------------- 7 [E] COG3869 Arginine kinase 2 3 3 6 ------------------|----||------------- 7 [S] COG3870 Uncharacterized protein conserved in bacteria 2 3 3 5 --------------------|--||------------- 5 [S] COG3876 Uncharacterized protein conserved in bacteria 3 3 3 3 ---------------|--|----|-------------- 3 [S] COG3877 Uncharacterized protein conserved in bacteria 2 3 3 5 ----------------------|||------------- 12 [S] COG3879 Uncharacterized protein conserved in bacteria 2 3 3 7 --------------------|--||------------- 7 [S] COG3880 Uncharacterized protein with conserved CXXC pairs 2 3 3 4 ------------------|----||------------- 4 [S] COG3881 Uncharacterized protein conserved in bacteria 1 2 3 7 -----------------------|||------------ 11 [S] COG3883 Uncharacterized protein conserved in bacteria 2 3 3 7 ----------------------||-|------------ 9 [I] COG3884 Acyl-ACP thioesterase 2 3 3 4 ----|-|--|---------------------------- 4 [K] COG3888 Predicted transcriptional regulator 2 3 3 4 --|---|-----------------------------|- 8 [R] COG3894 Uncharacterized metal-binding protein 1 1 3 3 ---------------------------|||-------- 3 [R] COG3907 PAP2 (acid phosphatase) superfamily protein 1 3 3 6 ---------------------------|-----|--|- 6 [C] COG3909 Cytochrome c556 1 2 3 4 ------------------------------|----||- 4 [R] COG3911 Predicted ATPase 1 3 3 4 ---------------------------|----|---|- 4 [S] COG3913 Uncharacterized protein conserved in bacteria 1 2 3 3 ---------------------------|--|-----|- 4 [S] COG3915 Uncharacterized protein conserved in bacteria 1 2 3 6 ---------------------------||-------|- 9 [S] COG3921 Uncharacterized protein conserved in bacteria 1 1 3 8 ----------------------------|-||------ 8 [L] COG3923 Primosomal replication protein N'' 1 3 3 6 ----------------------------|----|--|- 10 [R] COG3926 Putative secretion activating protein 1 2 3 4 ---------------------------|--|-----|- 4 [S] COG3930 Uncharacterized protein conserved in bacteria 2 3 3 4 -----------------------||---|--------- 7 [K] COG3933 Transcriptional antiterminator 1 2 3 8 -----------------------|||------------ 15 [L] COG3935 Putative primosome component and related proteins 2 3 3 3 -----------------------||---|--------- 3 [R] COG3940 Predicted beta-xylosidase 2 2 3 5 ------------------------||---------|-- 20 [R] COG3942 Surface antigen 1 2 3 5 ---------------------------||----|---- 5 [R] COG3943 Virulence protein 2 3 3 3 ------------------|----||------------- 4 [T] COG3947 Response regulator containing CheY-like receiver and SARP domains 1 2 3 3 ----------------------------|-|-----|- 4 [R] COG3950 Predicted ATP-binding protein involved in virulence 2 3 3 5 --------------------|--------|------|- 5 [S] COG3952 Predicted membrane protein 1 2 3 7 ----------------------------|-|-----|- 7 [C] COG3954 Phosphoribulokinase 2 3 3 3 -----------------------|-|-----|------ 4 [M] COG3955 Exopolysaccharide biosynthesis protein 2 3 3 6 ------------------------|---|-------|- 7 [I] COG3963 Phospholipid N-methyltransferase 3 3 3 3 -----------------||----|-------------- 3 [R] COG3968 Uncharacterized protein related to glutamine synthetase 3 3 3 3 ---------------------|-|------------|- 4 [S] COG3976 Uncharacterized protein conserved in bacteria 1 3 3 3 |-----||------------------------------ 3 [R] COG4001 Predicted metal-binding protein 1 3 3 4 -----|||------------------------------ 4 [S] COG4003 Uncharacterized protein conserved in archaea 1 3 3 3 ||-----|------------------------------ 6 [R] COG4007 Predicted dehydrogenase related to H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase 1 3 3 3 ||-----|------------------------------ 3 [S] COG4009 Uncharacterized protein conserved in archaea 1 3 3 3 ||-----|------------------------------ 3 [S] COG4010 Uncharacterized protein conserved in archaea 1 3 3 3 ||-----|------------------------------ 3 [S] COG4013 Uncharacterized protein conserved in archaea 1 3 3 3 ||-----|------------------------------ 3 [R] COG4015 Predicted dinucleotide-utilizing enzyme of the ThiF/HesA family 1 3 3 3 ||-----|------------------------------ 3 [S] COG4016 Uncharacterized protein conserved in archaea 1 3 3 3 ||-----|------------------------------ 3 [S] COG4017 Uncharacterized protein conserved in archaea 1 3 3 3 ||-----|------------------------------ 3 [S] COG4018 Uncharacterized protein conserved in archaea 1 3 3 3 ||-----|------------------------------ 3 [S] COG4019 Uncharacterized protein conserved in archaea 1 3 3 3 ||-----|------------------------------ 3 [S] COG4024 Uncharacterized protein conserved in archaea 1 3 3 4 |----|-|------------------------------ 4 [S] COG4025 Predicted membrane protein 1 3 3 3 |----|-|------------------------------ 3 [R] COG4026 Uncharacterized protein containing TOPRIM domain, potential nuclease 2 3 3 4 -----|-|--|--------------------------- 4 [S] COG4027 Uncharacterized protein conserved in archaea 1 3 3 3 |-----||------------------------------ 3 [S] COG4030 Uncharacterized protein conserved in archaea 1 3 3 3 ||-----|------------------------------ 3 [S] COG4035 Predicted membrane protein 1 3 3 3 ||-----|------------------------------ 3 [S] COG4036 Predicted membrane protein 1 3 3 3 ||-----|------------------------------ 3 [S] COG4037 Predicted membrane protein 1 3 3 3 ||-----|------------------------------ 3 [S] COG4038 Predicted membrane protein 1 3 3 3 ||-----|------------------------------ 3 [S] COG4039 Predicted membrane protein 1 3 3 3 ||-----|------------------------------ 3 [S] COG4040 Predicted membrane protein 1 3 3 3 ||-----|------------------------------ 3 [S] COG4041 Predicted membrane protein 1 3 3 3 ||-----|------------------------------ 3 [S] COG4042 Predicted membrane protein 2 3 3 4 -----|-|----------------|------------- 6 [S] COG4043 Uncharacterized conserved protein 1 3 3 4 -|---|-|------------------------------ 4 [R] COG4049 Uncharacterized protein containing archaeal-type C2H2 Zn-finger 1 3 3 3 ||-----|------------------------------ 3 [S] COG4053 Uncharacterized protein conserved in archaea 1 3 3 3 ||-----|------------------------------ 4 [S] COG4066 Uncharacterized protein conserved in archaea 2 2 3 3 -------|-------------------|--|------- 8 [O] COG4067 Uncharacterized protein conserved in archaea 1 3 3 3 |-----||------------------------------ 3 [S] COG4068 Uncharacterized protein containing a Zn-ribbon 1 3 3 3 ||-----|------------------------------ 3 [S] COG4071 Uncharacterized protein conserved in archaea 1 3 3 4 -|---|-|------------------------------ 4 [S] COG4072 Uncharacterized protein conserved in archaea 1 3 3 3 ||-----|------------------------------ 3 [C] COG4074 H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase 1 3 3 3 ||-----|------------------------------ 4 [S] COG4075 Uncharacterized conserved protein, homolog of nitrogen regulatory protein PII 1 3 3 3 ||-----|------------------------------ 3 [R] COG4076 Predicted RNA methylase 1 3 3 3 ||-----|------------------------------ 3 [S] COG4077 Uncharacterized protein conserved in archaea 1 3 3 3 ||-----|------------------------------ 3 [S] COG4078 Predicted membrane protein 1 3 3 3 ||-----|------------------------------ 3 [S] COG4084 Uncharacterized protein conserved in archaea 3 3 3 6 ----------------|-------|-----------|- 7 [E] COG4091 Predicted homoserine dehydrogenase 1 3 3 3 ---------------------------------||-|- 3 [M] COG4092 Predicted glycosyltransferase involved in capsule biosynthesis 1 3 3 4 -----------------------------|--|---|- 4 [G] COG4101 Predicted mannose-6-phosphate isomerase 1 2 3 4 --------------------------------|--||- 5 [S] COG4102 Uncharacterized protein conserved in bacteria 1 2 3 8 -----------------------|||------------ 8 [K] COG4109 Predicted transcriptional regulator containing CBS domains 3 3 3 5 ------------------|----|----|--------- 6 [R] COG4110 Uncharacterized protein involved in stress response 1 2 3 6 ---------------------------------|-||- 7 [R] COG4111 Uncharacterized conserved protein 2 3 3 7 ------------------------|---|-------|- 7 [R] COG4114 Uncharacterized Fe-S protein 2 3 3 6 -----------------------||-----------|- 10 [G] COG4124 Beta-mannanase 1 1 3 3 ---------------------------||-|------- 3 [R] COG4128 Zonula occludens toxin 1 3 3 5 ----------------------------|---|---|- 5 [G] COG4130 Predicted sugar epimerase 1 3 3 6 ---------------------------|------|-|- 6 [R] COG4132 ABC-type uncharacterized transport system, permease component 1 2 3 8 ----------------------------|-|-----|- 8 [R] COG4134 ABC-type uncharacterized transport system, periplasmic component 1 2 3 5 ----------------------------|-|-----|- 5 [R] COG4135 ABC-type uncharacterized transport system, permease component 1 2 3 5 ----------------------------|-|-----|- 5 [R] COG4136 ABC-type uncharacterized transport system, ATPase component 2 2 3 6 ------------------------|---|--|------ 6 [R] COG4146 Predicted symporter 1 2 3 9 ----------------------------|-|-----|- 9 [P] COG4150 ABC-type sulfate transport system, periplasmic component 1 2 3 5 ----------------------------|--|----|- 6 [R] COG4158 Predicted ABC-type sugar transport system, permease component 1 1 3 8 ----------------------------|-||------ 8 [E] COG4161 ABC-type arginine transport system, ATPase component 1 1 3 8 ----------------------------|-||------ 8 [V] COG4167 ABC-type antimicrobial peptide transport system, ATPase component 1 1 3 8 ----------------------------|-||------ 8 [V] COG4168 ABC-type antimicrobial peptide transport system, permease component 1 1 3 8 ----------------------------|-||------ 8 [V] COG4170 ABC-type antimicrobial peptide transport system, ATPase component 1 1 3 8 ----------------------------|-||------ 8 [V] COG4171 ABC-type antimicrobial peptide transport system, permease component 2 3 3 3 ---|-----------------------|--------|- 6 [K] COG4190 Predicted transcriptional regulator 1 1 3 3 ----------------------------|-||------ 3 [T] COG4192 Signal transduction histidine kinase regulating phosphoglycerate transport system 1 2 3 4 -----------------------|||------------ 6 [G] COG4193 Beta- N-acetylglucosaminidase 3 3 3 4 ----------------------|-|-----------|- 7 [R] COG4195 Phage-related replication protein 1 2 3 5 ----------------------------||------|- 8 [S] COG4197 Uncharacterized protein conserved in bacteria, prophage-related 2 3 3 3 -----------------------||----------|-- 6 [S] COG4200 Uncharacterized protein conserved in bacteria 2 2 3 7 ------------------------||----------|- 14 [G] COG4209 ABC-type polysaccharide transport system, permease component 2 3 3 3 -----------------------||----------|-- 7 [KT] COG4219 Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component 1 2 3 6 ----------------------------||------|- 14 [L] COG4220 Phage DNA packaging protein, Nu1 subunit of terminase 1 2 3 5 ----------------------------|--|-|---- 6 [R] COG4228 Mu-like prophage DNA circulation protein 1 2 3 7 ----------------------------|-|-----|- 11 [M] COG4238 Murein lipoprotein 2 3 3 3 ----------------||-----------------|-- 5 [QP] COG4242 Cyanophycinase and related exopeptidases 2 3 3 6 ----------------|-----------|-----|--- 8 [R] COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain 3 3 3 3 ----------------|-------|----------|-- 3 [I] COG4247 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) 3 3 3 5 ----------------|-|---------|--------- 5 [R] COG4248 Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains 2 3 3 3 ----------------|------------|------|- 15 [R] COG4249 Uncharacterized protein containing caspase domain 2 3 3 3 ---|------------||-------------------- 4 [T] COG4250 Predicted sensor protein/domain 1 2 3 3 ---------------------------||---|----- 17 [S] COG4253 Uncharacterized protein conserved in bacteria 1 2 3 4 -----------------------------|--||---- 4 [S] COG4255 Uncharacterized protein conserved in bacteria 1 3 3 7 ----------------------------|---|---|- 7 [P] COG4256 Hemin uptake protein 2 3 3 3 -----------------|---------|----|----- 4 [V] COG4257 Streptogramin lyase 1 2 3 4 ----------------------------||--|----- 5 [R] COG4258 Predicted exporter 2 2 3 4 ------------------------||------|----- 4 [S] COG4260 Putative virion core protein (lumpy skin disease virus) 1 2 3 4 ----------------------------||--|----- 5 [R] COG4261 Predicted acyltransferase 3 3 3 5 --------------|-------|---------|----- 6 [R] COG4262 Predicted spermidine synthase with an N-terminal membrane domain 1 3 3 4 ---------------------------|----|---|- 5 [C] COG4263 Nitrous oxide reductase 2 3 3 4 ----|---------------------------|---|- 5 [S] COG4275 Uncharacterized conserved protein 3 3 3 3 ---------|------|-------------------|- 4 [S] COG4280 Predicted membrane protein 3 3 3 3 ---------------||-------------------|- 4 [S] COG4288 Uncharacterized protein conserved in bacteria 2 3 3 4 ---------------|------------|-------|- 4 [S] COG4289 Uncharacterized protein conserved in bacteria 2 3 3 6 ------------------|-------------|---|- 6 [S] COG4291 Predicted membrane protein 3 3 3 4 ----------------|-|---|--------------- 6 [S] COG4293 Uncharacterized protein conserved in bacteria 3 3 3 3 ----------------|-|----|-------------- 3 [S] COG4295 Uncharacterized protein conserved in bacteria 3 3 3 3 ----------------|-|----|-------------- 3 [S] COG4296 Uncharacterized protein conserved in bacteria 3 3 3 4 ------------------|-----|-----------|- 4 [S] COG4297 Uncharacterized protein containing double-stranded beta helix domain 3 3 3 3 ----------------|-|-----------------|- 3 [S] COG4298 Uncharacterized protein conserved in bacteria 3 3 3 3 ----------------|-|----------------|-- 3 [S] COG4299 Uncharacterized conserved protein 2 3 3 4 -----------------------|----|----|---- 4 [S] COG4304 Uncharacterized protein conserved in bacteria 2 3 3 3 ------------------------|----|--|----- 3 [G] COG4305 Endoglucanase C-terminal domain/subunit and related proteins 2 3 3 3 -----------------------|-----|--|----- 3 [S] COG4306 Uncharacterized protein conserved in bacteria 2 3 3 5 ----------------------|---------|---|- 5 [S] COG4307 Uncharacterized protein conserved in bacteria 2 3 3 4 ----------------------|---------|--|-- 5 [Q] COG4308 Limonene-1,2-epoxide hydrolase 2 3 3 4 -----------------------|----------|-|- 4 [R] COG4310 Uncharacterized protein conserved in bacteria with an aminopeptidase-like domain 1 3 3 6 ---------------------------|----|---|- 14 [E] COG4311 Sarcosine oxidase delta subunit 1 3 3 5 ---------------------------|----|---|- 10 [S] COG4312 Uncharacterized protein conserved in bacteria 1 3 3 4 ---------------------------|----|---|- 8 [C] COG4313 Protein involved in meta-pathway of phenol degradation 1 3 3 4 ---------------------------|----|---|- 5 [S] COG4315 Uncharacterized protein conserved in bacteria 1 3 3 4 -------------------------------|-|--|- 4 [S] COG4316 Uncharacterized protein conserved in bacteria 1 3 3 4 ---------------------------|----|---|- 4 [S] COG4318 Uncharacterized protein conserved in bacteria 1 3 3 3 -----------------------------|--|---|- 3 [S] COG4320 Uncharacterized protein conserved in bacteria 1 3 3 6 ---------------------------|----|---|- 9 [R] COG4321 Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis 1 3 3 3 -----------------------------|--|--|-- 3 [S] COG4322 Uncharacterized protein conserved in bacteria 1 3 3 3 ---------------------------|----|--|-- 3 [S] COG4323 Predicted membrane protein 1 3 3 3 ---------------------------|----|---|- 3 [R] COG4324 Predicted aminopeptidase 3 3 3 5 ----------------|-----|--------|------ 5 [S] COG4325 Predicted membrane protein 3 3 3 3 ----------------|-------|-----|------- 3 [R] COG4326 Sporulation control protein 3 3 3 3 ----------------|-------|-----------|- 3 [S] COG4329 Predicted membrane protein 2 3 3 4 -----------------------|----|-------|- 4 [S] COG4332 Uncharacterized protein conserved in bacteria 2 3 3 4 ------------------------|---|-------|- 4 [S] COG4333 Uncharacterized protein conserved in bacteria 2 3 3 3 -------------------------|---|------|- 3 [S] COG4334 Uncharacterized protein conserved in bacteria 2 3 3 3 ------------------------|------|----|- 4 [L] COG4335 DNA alkylation repair enzyme 2 3 3 3 ----------------|-------------|----|-- 3 [S] COG4337 Uncharacterized protein conserved in bacteria 2 3 3 3 ----------------|-------------|----|-- 3 [S] COG4338 Uncharacterized protein conserved in bacteria 2 3 3 3 ----------------|----------|--------|- 3 [S] COG4339 Uncharacterized protein conserved in bacteria 2 3 3 3 ----------------|-------------|----|-- 3 [S] COG4340 Uncharacterized protein conserved in bacteria 2 2 3 3 -----|---||--------------------------- 5 [S] COG4342 Uncharacterized protein conserved in archaea 2 3 3 4 ----||---|---------------------------- 4 [S] COG4344 Uncharacterized protein conserved in archaea 2 3 3 3 ---------|------||-------------------- 6 [G] COG4354 Predicted bile acid beta-glucosidase 2 3 3 3 -----------|----||-------------------- 4 [F] COG4360 ATP adenylyltransferase (5',5'''-P-1,P-4-tetraphosphate phosphorylase II) 2 2 3 4 ------------------|-----||------------ 4 [S] COG4367 Uncharacterized protein conserved in bacteria 2 3 3 3 ----------------|||------------------- 4 [S] COG4370 Uncharacterized protein conserved in bacteria 2 3 3 3 ----------------|||------------------- 3 [S] COG4371 Predicted membrane protein 2 3 3 3 ----------------|||------------------- 3 [S] COG4372 Uncharacterized protein conserved in bacteria with the myosin-like domain 2 2 3 3 ------------------|---------|--|------ 3 [R] COG4373 Mu-like prophage FluMu protein gp28 2 2 3 3 ------------------|----------------|-| 3 [S] COG4374 Uncharacterized protein conserved in bacteria 2 2 3 3 ------------------------||------|----- 3 [S] COG4377 Predicted membrane protein 2 3 3 3 -----------------------||---------|--- 3 [S] COG4378 Uncharacterized protein conserved in bacteria 1 2 3 5 ----------------------------|--|-|---- 6 [R] COG4379 Mu-like prophage tail protein gpP 1 2 3 5 ----------------------------|--|-|---- 6 [S] COG4381 Mu-like prophage protein gp46 1 2 3 4 ----------------------------|--|-|---- 6 [S] COG4382 Mu-like prophage protein gp16 1 2 3 4 ----------------------------|--|-|---- 6 [S] COG4383 Mu-like prophage protein gp29 1 2 3 5 ----------------------------|--|-|---- 6 [S] COG4384 Mu-like prophage protein gp45 1 2 3 5 ----------------------------|--|-|---- 5 [R] COG4386 Mu-like prophage tail sheath protein gpL 1 2 3 4 ----------------------------|--|-|---- 4 [S] COG4387 Mu-like prophage protein gp36 1 2 3 4 ----------------------------|--|-|---- 4 [R] COG4388 Mu-like prophage I protein 1 2 3 4 -------------------------------|||---- 4 [L] COG4389 Site-specific recombinase 1 2 3 4 -------------------------------|||---- 4 [S] COG4390 Uncharacterized protein conserved in bacteria 1 2 3 3 ----------------------------|--|-|---- 3 [R] COG4396 Mu-like prophage host-nuclease inhibitor protein Gam 1 2 3 3 ----------------------------|--|-|---- 3 [R] COG4397 Mu-like prophage major head subunit gpT 2 3 3 4 ----------------||----|--------------- 6 [S] COG4398 Uncharacterized protein conserved in bacteria 2 3 3 5 ----------------||------|------------- 5 [E] COG4401 Chorismate mutase 2 3 3 4 ----------------||----|--------------- 4 [S] COG4402 Uncharacterized protein conserved in bacteria 2 2 3 4 ------------------------|--||--------- 4 [S] COG4408 Uncharacterized protein conserved in bacteria 2 3 3 3 -----------------------||-----|------- 3 [S] COG4412 Uncharacterized protein conserved in bacteria 2 2 3 3 -----------------------|----|--|------ 3 [R] COG4416 Mu-like prophage protein Com 2 2 3 3 ------------------------|----------|-| 5 [G] COG4421 Capsular polysaccharide biosynthesis protein 2 2 3 5 ----------------------|------------||- 5 [S] COG4427 Uncharacterized protein conserved in bacteria 2 3 3 3 ----------------||------------|------- 4 [S] COG4446 Uncharacterized protein conserved in bacteria 2 3 3 6 ----------------||------------------|- 6 [E] COG4448 L-asparaginase II 2 3 3 3 ----------------||-----------------|-- 3 [R] COG4449 Predicted protease of the Abi (CAAX) family 2 3 3 3 ----------------||------------------|- 6 [C] COG4451 Ribulose bisphosphate carboxylase small subunit 1 2 3 4 ---------------------------||-------|- 4 [R] COG4455 Protein of avirulence locus involved in temperature-dependent protein secretion 1 2 3 4 ----------------------------|--|----|- 4 [S] COG4457 Uncharacterized protein conserved in bacteria, putative virulence factor 1 2 3 4 ----------------------------|--|----|- 4 [S] COG4458 Uncharacterized protein conserved in bacteria, putative virulence factor 1 2 3 4 ---------------------------|--|-----|- 4 [C] COG4459 Periplasmic nitrate reductase system, NapE component 1 2 3 3 ---------------------------||-------|- 3 [S] COG4460 Uncharacterized protein conserved in bacteria 1 2 3 8 -----------------------|||------------ 8 [K] COG4463 Transcriptional repressor of class III stress genes 1 2 3 5 -----------------------|||------------ 7 [GM] COG4464 Capsular polysaccharide biosynthesis protein 1 2 3 8 -----------------------|||------------ 9 [K] COG4465 Pleiotropic transcriptional repressor 1 2 3 8 -----------------------|||------------ 8 [S] COG4466 Uncharacterized protein conserved in bacteria 1 2 3 7 -----------------------|||------------ 7 [S] COG4472 Uncharacterized protein conserved in bacteria 1 3 3 5 -----------------------|-||----------- 5 [S] COG4478 Predicted membrane protein 1 2 3 6 -----------------------|||------------ 6 [S] COG4481 Uncharacterized protein conserved in bacteria 2 3 3 5 -------------------|---||------------- 5 [R] COG4492 ACT domain-containing protein 1 2 3 4 -----------------------|||------------ 7 [S] COG4495 Uncharacterized protein conserved in bacteria 2 3 3 6 -----------------------||----|-------- 6 [S] COG4496 Uncharacterized protein conserved in bacteria 1 3 3 3 -----------------------||-|----------- 3 [S] COG4508 Uncharacterized protein conserved in bacteria 1 1 3 3 ---------------------------|||-------- 3 [S] COG4517 Uncharacterized protein conserved in bacteria 1 1 3 3 ----------------------------|-||------ 3 [S] COG4518 Mu-like prophage FluMu protein gp41 1 1 3 3 ---------------------------||-|------- 3 [S] COG4519 Uncharacterized protein conserved in bacteria 1 2 3 7 --------------------------------|---|| 7 [M] COG4520 Surface antigen 1 2 3 7 ---------------------------||-------|- 7 [P] COG4521 ABC-type taurine transport system, periplasmic component 1 2 3 8 ---------------------------||-------|- 8 [P] COG4525 ABC-type taurine transport system, ATPase component 2 2 3 3 ---|-------------------------------||- 3 [S] COG4538 Uncharacterized conserved protein 3 3 3 4 -------------------|-|---------|------ 4 [O] COG4545 Glutaredoxin-related protein 1 2 3 6 ----------------------------|------||- 6 [H] COG4547 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) 2 3 3 6 ------------------------|--|--------|- 6 [P] COG4548 Nitric oxide reductase activation protein 1 3 3 4 ------------------------------|-|---|- 4 [T] COG4564 Signal transduction histidine kinase 1 1 3 7 ---------------------------||-|------- 7 [K] COG4568 Transcriptional antiterminator 2 3 3 6 ----------------------|-----|---|----- 6 [Q] COG4569 Acetaldehyde dehydrogenase (acetylating) 2 3 3 6 ----------------|-----------|--------| 7 [R] COG4572 Putative cation transport regulator 1 3 3 9 ----------------------------|---|---|- 12 [G] COG4573 Predicted tagatose 6-phosphate kinase 1 2 3 7 ---------------------------||--------| 7 [R] COG4574 Serine protease inhibitor ecotin 1 2 3 7 ---------------------------||---|----- 7 [T] COG4579 Isocitrate dehydrogenase kinase/phosphatase 1 2 3 7 ----------------------------|-|-|----- 9 [G] COG4580 Maltoporin (phage lambda and maltose receptor) 1 2 3 7 ----------------------------|-|-|----- 7 [S] COG4582 Uncharacterized protein conserved in bacteria 1 3 3 6 ---------------------------|----|---|- 13 [E] COG4583 Sarcosine oxidase gamma subunit 1 1 3 3 ---------------------------||-|------- 3 [R] COG4590 ABC-type uncharacterized transport system, permease component 1 1 3 7 ---------------------------||-|------- 7 [P] COG4592 ABC-type Fe2+-enterobactin transport system, periplasmic component 2 2 3 4 ------------------------|---|--|------ 6 [P] COG4594 ABC-type Fe3+-citrate transport system, periplasmic component 2 3 3 6 ------------------------|---|---|----- 6 [R] COG4619 ABC-type uncharacterized transport system, ATPase component 2 2 3 3 ------------------|---------|-|------- 4 [S] COG4628 Uncharacterized conserved protein 1 2 3 3 -----------------------|||------------ 4 [G] COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase 2 3 3 3 ----------------|------|-|------------ 4 [S] COG4633 Uncharacterized protein conserved in bacteria 2 3 3 3 ----------------||-----------|-------- 7 [S] COG4634 Uncharacterized protein conserved in bacteria 2 3 3 3 ----------------|----------|--------|- 5 [R] COG4637 Predicted ATPase 2 3 3 4 -----------------------||-----------|- 8 [S] COG4641 Uncharacterized protein conserved in bacteria 1 2 3 6 ----------------------------||--|----- 9 [S] COG4643 Uncharacterized protein conserved in bacteria 1 2 3 4 ----------------------------|---||---- 5 [S] COG4648 Predicted membrane protein 1 2 3 6 ---------------------------||---|----- 6 [KT] COG4650 Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain 2 3 3 3 --------------|------------|----|----- 5 [C] COG4654 Cytochrome c551/c552 1 3 3 5 ---------------------------|----|---|- 5 [S] COG4655 Predicted membrane protein 2 3 3 5 ----------------||------------------|- 10 [R] COG4671 Predicted glycosyl transferase 1 2 3 6 ---------------------------||---|----- 26 [S] COG4672 Phage-related protein 2 3 3 3 ----------------|---------------|---|- 7 [S] COG4675 Microcystin-dependent protein 1 2 3 5 ---------------------------||---|----- 7 [S] COG4676 Uncharacterized protein conserved in bacteria 2 3 3 7 -----------------------|----|---|----- 7 [G] COG4677 Pectin methylesterase 2 3 3 7 ----------------|-----------|-------|- 7 [S] COG4680 Uncharacterized protein conserved in bacteria 1 2 3 7 ---------------------------||---|----- 7 [S] COG4681 Uncharacterized protein conserved in bacteria 2 3 3 7 ------------------------|---|---|----- 10 [S] COG4682 Predicted membrane protein 3 3 3 4 ----------------|-----|-----|--------- 6 [S] COG4683 Uncharacterized protein conserved in bacteria 1 2 3 5 ---------------------------||---|----- 5 [S] COG4685 Uncharacterized protein conserved in bacteria 1 2 3 5 -----------------------|||------------ 6 [S] COG4687 Uncharacterized protein conserved in bacteria 1 2 3 4 ----------------------------|--||----- 5 [S] COG4688 Uncharacterized protein conserved in bacteria 2 3 3 3 -----------------------|--------|---|- 5 [Q] COG4689 Acetoacetate decarboxylase 2 3 3 4 ----------------------|------|------|- 5 [R] COG4691 Plasmid stability protein 1 3 3 5 ----------------------------|-----|-|- 5 [G] COG4692 Predicted neuraminidase (sialidase) 1 2 3 3 ---------------------------||---|----- 4 [Q] COG4693 Oxidoreductase (NAD-binding), involved in siderophore biosynthesis 1 3 3 4 -----------------------------|--|-|--- 4 [S] COG4694 Uncharacterized protein conserved in bacteria 2 2 3 4 -----|---||--------------------------- 5 [S] COG4697 Uncharacterized protein conserved in archaea 1 3 3 4 ----------------------------|---|--|-- 4 [S] COG4700 Uncharacterized protein conserved in bacteria containing a divergent form of TPR repeats 1 1 3 4 ----------------------------|-||------ 4 [S] COG4701 Uncharacterized protein conserved in bacteria 2 3 3 3 ----------------|---------------|--|-- 4 [S] COG4704 Uncharacterized protein conserved in bacteria 2 3 3 3 ----------------|---------------|---|- 4 [S] COG4705 Uncharacterized membrane-anchored protein conserved in bacteria 1 2 3 4 ----------------------------|---||---- 5 [I] COG4706 Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase 1 2 3 5 -----------------------|||------------ 5 [S] COG4708 Predicted membrane protein 1 3 3 3 -----------------------------|----|-|- 3 [R] COG4710 Predicted DNA-binding protein with an HTH domain 2 3 3 3 ------------------|----|-|------------ 3 [S] COG4712 Uncharacterized protein conserved in bacteria 1 2 3 3 ----------------------------|--||----- 3 [S] COG4714 Uncharacterized membrane-anchored protein conserved in bacteria 3 3 3 5 --|---------------------|-----------|- 5 [S] COG4717 Uncharacterized conserved protein 1 2 3 6 ---------------------------||---|----- 21 [S] COG4718 Phage-related protein 3 3 3 3 ----------------|-|-----------------|- 3 [S] COG4719 Uncharacterized protein conserved in bacteria 2 2 3 4 ----------------------|-||------------ 4 [S] COG4721 Predicted membrane protein 1 2 3 6 -----------------------|||------------ 10 [S] COG4722 Phage-related protein 1 2 3 6 ---------------------------||---|----- 25 [S] COG4723 Phage-related protein, tail component 3 3 3 3 -----------|----|-------------------|- 3 [TK] COG4725 Transcriptional activator, adenine-specific DNA methyltransferase 1 2 3 3 ----------------------------||--|----- 3 [S] COG4727 Uncharacterized protein conserved in bacteria 2 3 3 3 -----------------------|---|----|----- 3 [S] COG4728 Uncharacterized protein conserved in bacteria 1 2 3 6 ---------------------------||---|----- 33 [S] COG4733 Phage-related protein, tail component 2 3 3 3 ----------------|-----------|-------|- 3 [R] COG4734 Antirestriction protein 1 3 3 4 --|-|-|------------------------------- 7 [K] COG4738 Predicted transcriptional regulator 1 3 3 3 --|---||------------------------------ 4 [S] COG4739 Uncharacterized protein containing a ferredoxin domain 1 3 3 3 |-|----|------------------------------ 3 [R] COG4740 Predicted metalloprotease 1 3 3 3 |-|---|------------------------------- 31 [K] COG4742 Predicted transcriptional regulator 1 3 3 4 |-|--|-------------------------------- 4 [S] COG4743 Predicted membrane protein 1 3 3 3 --||--|------------------------------- 5 [O] COG4745 Predicted membrane-bound mannosyltransferase 1 3 3 3 |-|---|------------------------------- 4 [R] COG4747 ACT domain-containing protein 1 3 3 3 --||--|------------------------------- 3 [S] COG4749 Uncharacterized protein conserved in archaea 3 3 3 3 --------------||---|------------------ 3 [S] COG4752 Uncharacterized protein conserved in bacteria 2 2 3 7 -------------------|----||------------ 16 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain 1 1 3 3 --------|||--------------------------- 3 [S] COG4755 Uncharacterized protein conserved in archaea 2 2 3 3 ------|-|-|--------------------------- 3 [R] COG4756 Predicted cation transporter 2 3 3 3 ----------------||----|--------------- 9 [O] COG4759 Uncharacterized protein conserved in bacteria containing thioredoxin-like domain 2 3 3 5 ----------------------|-----|-------|- 5 [S] COG4763 Predicted membrane protein 1 1 3 7 -----------------------------------||| 7 [S] COG4765 Uncharacterized protein conserved in bacteria 1 2 3 8 ---------------------------||----|---- 13 [P] COG4773 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid 1 1 3 9 ----------------------------|-||------ 9 [K] COG4776 Exoribonuclease II 2 3 3 6 ----------------|---------------|---|- 12 [S] COG4782 Uncharacterized protein conserved in bacteria 1 1 3 8 ----------------------------|-||------ 8 [R] COG4785 Lipoprotein NlpI, contains TPR repeats 1 2 3 6 ---------------------------||-------|- 7 [U] COG4792 Type III secretory pathway, component EscU 2 2 3 3 ----------------|------------------||- 7 [R] COG4798 Predicted methyltransferase 1 3 3 3 -||---|------------------------------- 3 [K] COG4800 Predicted transcriptional regulator with an HTH domain 3 3 3 6 --|--------------|------------------|- 9 [S] COG4803 Predicted membrane protein 2 3 3 3 ----------------------|------|-----|-- 8 [S] COG4805 Uncharacterized protein conserved in bacteria 2 2 3 7 -------------------|-------||--------- 7 [S] COG4807 Uncharacterized protein conserved in bacteria 1 3 3 4 -||--|-------------------------------- 7 [G] COG4809 Archaeal ADP-dependent phosphofructokinase/glucokinase 3 3 3 6 -------------------|----|---|--------- 7 [E] COG4810 Ethanolamine utilization protein 2 2 3 7 ------------------------|---|--|------ 7 [S] COG4811 Predicted membrane protein 3 3 3 6 -------------------|----|---|--------- 6 [E] COG4812 Ethanolamine utilization cobalamin adenosyltransferase 3 3 3 6 -------------------|----|---|--------- 8 [E] COG4816 Ethanolamine utilization protein 1 3 3 3 -||---|------------------------------- 6 [S] COG4818 Predicted membrane protein 3 3 3 6 -------------------|----|---|--------- 6 [E] COG4819 Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition 3 3 3 6 -------------------|----|---|--------- 6 [E] COG4820 Ethanolamine utilization protein, possible chaperonin 3 3 3 3 -------------------|----|------|------ 5 [V] COG4823 Abortive infection bacteriophage resistance protein 3 3 3 3 --|-----|-------|--------------------- 5 [O] COG4826 Serine protease inhibitor 1 3 3 3 |-|----|------------------------------ 5 [R] COG4827 Predicted transporter 3 3 3 3 --|--------------||------------------- 5 [S] COG4828 Predicted membrane protein 3 3 3 3 --|------|----|----------------------- 4 [S] COG4831 Uncharacterized conserved protein 2 3 3 3 ------------------------|----|------|- 4 [S] COG4834 Uncharacterized protein conserved in bacteria 2 3 3 9 ----------------------|||------------- 32 [S] COG4842 Uncharacterized protein conserved in bacteria 2 2 3 4 ----|---|-|--------------------------- 4 [S] COG4847 Uncharacterized protein conserved in archaea 2 2 3 4 ------------------------||----------|- 4 [S] COG4852 Predicted membrane protein 1 3 3 3 --|--||------------------------------- 4 [S] COG4854 Predicted membrane protein 1 3 3 3 |-|---|------------------------------- 4 [S] COG4855 Uncharacterized protein conserved in archaea 1 2 3 7 -----------------------|||------------ 7 [S] COG4856 Uncharacterized protein conserved in bacteria 3 3 3 4 -------------------|----|-----------|- 4 [R] COG4857 Predicted kinase 2 3 3 4 -------------------|-------|-----|---- 4 [S] COG4859 Uncharacterized protein conserved in bacteria 1 3 3 4 --|-|-|------------------------------- 4 [S] COG4860 Uncharacterized protein conserved in archaea 3 3 3 4 ---|---------------|--------|--------- 4 [E] COG4865 Glutamate mutase epsilon subunit 3 3 3 4 -------------------|--|--|------------ 4 [S] COG4868 Uncharacterized protein conserved in bacteria 3 3 3 3 ---------------|--------|---|--------- 4 [Q] COG4869 Propanediol utilization protein 1 3 3 3 |-|---|------------------------------- 4 [S] COG4871 Uncharacterized protein conserved in archaea 3 3 3 4 --|-------------|-------------------|- 4 [S] COG4872 Predicted membrane protein 2 3 3 3 -------------------|----------|-|----- 3 [S] COG4874 Uncharacterized protein conserved in bacteria containing a pentein-type domain 1 3 3 3 -----------------------------|--|---|- 3 [S] COG4875 Uncharacterized protein conserved in bacteria with a cystatin-like fold 3 3 3 3 ----------------------|--|----------|- 3 [S] COG4877 Uncharacterized protein conserved in bacteria 3 3 3 3 ---------------|---|---|-------------- 4 [S] COG4878 Uncharacterized protein conserved in bacteria 1 1 3 3 --------|||--------------------------- 3 [S] COG4879 Uncharacterized protein conserved in archaea 2 3 3 3 -|----|-|----------------------------- 3 [R] COG4880 Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats 2 2 3 3 ------|-|-|--------------------------- 3 [S] COG4881 Predicted membrane protein 1 1 3 3 --------|||--------------------------- 3 [R] COG4882 Predicted aminopeptidase, Iap family 1 3 3 3 |-|---|------------------------------- 3 [S] COG4883 Uncharacterized protein conserved in archaea 3 3 3 3 -------------------|----|---|--------- 3 [S] COG4884 Uncharacterized protein conserved in bacteria 1 3 3 3 --||--|------------------------------- 3 [S] COG4885 Uncharacterized protein conserved in archaea 1 3 3 3 -||----|------------------------------ 3 [R] COG4887 Uncharacterized metal-binding protein conserved in archaea 3 3 3 6 ----------------------|-|---------|--- 8 [R] COG4889 Predicted helicase 1 2 3 3 ----------------------------|-|-----|- 3 [S] COG4890 Predicted outer membrane lipoprotein 2 3 3 3 |-|--------------------|-------------- 3 [R] COG4892 Predicted heme/steroid binding protein 1 2 3 3 ---------------------------||-------|- 3 [S] COG4893 Uncharacterized protein conserved in bacteria 3 3 3 3 --|---------------|-----|------------- 3 [S] COG4895 Uncharacterized conserved protein 2 2 3 3 ------------------------||----------|- 3 [S] COG4898 Uncharacterized protein conserved in bacteria 2 3 3 3 ----------------------|----------|-|-- 3 [S] COG4899 Uncharacterized protein conserved in bacteria 1 1 3 3 --------|||--------------------------- 3 [R] COG4900 Predicted metallopeptidase 1 3 3 3 -||--|-------------------------------- 3 [S] COG4902 Uncharacterized protein conserved in archaea 2 2 3 3 ------|-|-|--------------------------- 3 [S] COG4904 Uncharacterized protein conserved in archaea 1 2 3 3 -----------------------|||------------ 3 [S] COG4905 Predicted membrane protein 1 3 3 3 |-|--|-------------------------------- 3 [S] COG4906 Predicted membrane protein 2 3 3 3 -||----------------|------------------ 3 [S] COG4907 Predicted membrane protein 2 3 3 3 ------------------------|---|-------|- 3 [Q] COG4909 Propanediol dehydratase, large subunit 2 3 3 3 ------------------------|---|-------|- 3 [Q] COG4910 Propanediol dehydratase, small subunit 2 2 3 3 --------||----|----------------------- 3 [S] COG4911 Uncharacterized conserved protein 2 2 3 3 ----------------------|-----||-------- 3 [S] COG4913 Uncharacterized protein conserved in bacteria 1 1 3 3 --------|||--------------------------- 3 [R] COG4914 Predicted nucleotidyltransferase 2 3 3 3 -----------------|--------------|---|- 3 [S] COG4916 Uncharacterized protein containing a TIR (Toll-Interleukin 1-resistance) domain 3 3 3 6 -------------------|----|---|--------- 9 [E] COG4917 Ethanolamine utilization protein 1 1 3 3 --------|||--------------------------- 3 [J] COG4919 Ribosomal protein S30 1 1 3 3 --------|||--------------------------- 3 [S] COG4920 Predicted membrane protein 1 3 3 3 -||----|------------------------------ 3 [S] COG4921 Uncharacterized protein conserved in archaea 3 3 3 3 --|------------|--------------------|- 3 [S] COG4923 Uncharacterized conserved protein 2 2 3 3 ----------------------|-----||-------- 3 [S] COG4924 Uncharacterized protein conserved in bacteria 2 3 3 3 --|--------------------------|--|----- 3 [S] COG4925 Uncharacterized conserved protein 1 2 3 4 -----------------------|||------------ 5 [S] COG4926 Phage-related protein 3 3 3 3 -------------------|----|-----------|- 3 [R] COG4927 Predicted choloylglycine hydrolase 3 3 3 3 --|-----|-------------------|--------- 3 [O] COG4930 Predicted ATP-dependent Lon-type protease 3 3 3 4 ----|----|-------------|-------------- 12 [O] COG4934 Predicted protease 2 3 3 3 -----------------------||---|--------- 3 [TK] COG4936 Predicted sensor domain 1 3 3 3 |||----------------------------------- 3 [J] COG4937 Predicted regulatory domain of prephenate dehydrogenase 3 3 3 3 --------|---------------|-----|------- 3 [S] COG4938 Uncharacterized conserved protein 3 3 3 3 -------------------|-|--|------------- 3 [S] COG4939 Major membrane immunogen, membrane-anchored lipoprotein 2 2 3 10 ------------------------||--------|--- 10 [U] COG4940 Competence protein ComGF 2 3 3 3 ----||--|----------------------------- 4 [G] COG4945 Membrane-anchored protein predicted to be involved in regulation of amylopullulanase 2 2 3 4 ----|---||---------------------------- 4 [S] COG4946 Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system 3 3 3 4 ----------------------|--|--|--------- 5 [S] COG4951 Uncharacterized protein conserved in bacteria 1 3 3 4 -----------------------------|--|---|- 5 [OU] COG4959 Type IV secretory pathway, protease TraF 2 3 3 6 -----------||---------|--------------- 7 [I] COG4981 Enoyl reductase domain of yeast-type FAS1 2 3 3 6 -----------||---------|--------------- 7 [I] COG4982 3-oxoacyl-[acyl-carrier protein] reductase 2 2 3 3 -------------------|--------|--|------ 3 [S] COG4984 Predicted membrane protein 1 1 3 3 ---------------------------||-|------- 3 [P] COG4985 ABC-type phosphate transport system, auxiliary component 2 3 3 6 -----------------------||-----------|- 12 [S] COG4991 Uncharacterized protein with a bacterial SH3 domain homologue 1 2 3 8 ---------------------------||-------|- 11 [G] COG4993 Glucose dehydrogenase 2 3 3 3 -----------------------||-------|----- 3 [S] COG4994 Uncharacterized protein conserved in bacteria 2 3 3 3 ----------------||-----------------|-- 17 [S] COG4995 Uncharacterized protein conserved in bacteria 1 1 3 3 --------|||--------------------------- 3 [R] COG4996 Predicted phosphatase 2 2 3 3 -------||-|--------------------------- 3 [L] COG4998 Predicted endonuclease (RecB family) 1 2 3 3 --------------------------------|--||- 3 [T] COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain 2 2 3 8 ------------------|-----||------------ 8 [T] COG5002 Signal transduction histidine kinase 1 2 3 4 ----------------------------|--|-|---- 4 [R] COG5003 Mu-like prophage protein gp37 1 2 3 3 ----------------------------|--|-|---- 5 [R] COG5005 Mu-like prophage protein gpG 3 3 3 3 -------||------|---------------------- 3 [R] COG5014 Predicted Fe-S oxidoreductase 3 3 3 3 ------------|-----------|--|---------- 3 [R] COG5018 Inhibitor of the KinA pathway to sporulation, predicted exonuclease 2 3 3 3 -----------|||------------------------ 17 [DZ] COG5019 Septin family protein 2 3 3 3 -----------|||------------------------ 16 [G] COG5020 Mannosyltransferase 2 3 3 3 -----------|||------------------------ 14 [O] COG5021 Ubiquitin-protein ligase 2 3 3 3 -----------|||------------------------ 12 [Z] COG5022 Myosin heavy chain 2 3 3 3 -----------|||------------------------ 11 [Z] COG5023 Tubulin 2 3 3 3 -----------|||------------------------ 16 [D] COG5024 Cyclin 2 3 3 3 -----------|||------------------------ 10 [K] COG5025 Transcription factor of the Forkhead/HNF3 family 2 3 3 3 -----------|||------------------------ 7 [B] COG5027 Histone acetyltransferase (MYST family) 2 3 3 3 -----------|||------------------------ 7 [U] COG5028 Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 2 3 3 3 -----------|||------------------------ 7 [O] COG5029 Prenyltransferase, beta subunit 2 3 3 3 -----------|||------------------------ 7 [U] COG5030 Clathrin adaptor complex, small subunit 2 3 3 3 -----------||---|--------------------- 6 [H] COG5031 Uncharacterized protein involved in ubiquinone biosynthesis 2 3 3 3 -----------|||------------------------ 22 [TDBLU] COG5032 Phosphatidylinositol kinase and protein kinases of the PI-3 kinase family 2 3 3 3 -----------|||------------------------ 6 [K] COG5033 Transcription initiation factor IIF, auxiliary subunit 2 3 3 3 -----------|||------------------------ 6 [B] COG5034 Chromatin remodeling protein, contains PhD zinc finger 2 3 3 3 -----------|||------------------------ 6 [DKT] COG5035 Cell cycle control protein 2 3 3 3 -----------|||------------------------ 6 [P] COG5036 SPX domain-containing protein involved in vacuolar polyphosphate accumulation 2 3 3 3 -----------|||------------------------ 6 [TG] COG5037 Gluconate transport-inducing protein 2 3 3 3 -----------|||------------------------ 7 [R] COG5038 Ca2+-dependent lipid-binding protein, contains C2 domain 3 3 3 3 ------------|---|-------|------------- 6 [GM] COG5039 Exopolysaccharide biosynthesis protein 2 3 3 3 -----------|||------------------------ 5 [T] COG5040 14-3-3 family protein 2 3 3 3 -----------|||------------------------ 5 [TDK] COG5041 Casein kinase II, beta subunit 2 3 3 3 -----------|||------------------------ 5 [U] COG5043 Vacuolar protein sorting-associated protein 2 3 3 3 -----------|||------------------------ 6 [O] COG5044 RAB proteins geranylgeranyltransferase component A (RAB escort protein) 2 3 3 3 -----------|||------------------------ 5 [J] COG5045 Ribosomal protein S10E 2 3 3 3 -----------|||------------------------ 5 [O] COG5046 Protein involved in Mod5 protein sorting 2 3 3 3 -----------|||------------------------ 5 [U] COG5047 Vesicle coat complex COPII, subunit SEC23 2 3 3 3 -----------|||------------------------ 48 [R] COG5048 FOG: Zn-finger 2 3 3 3 -----------|||------------------------ 5 [LDA] COG5049 5'-3' exonuclease 2 3 3 3 -----------|||------------------------ 5 [J] COG5051 Ribosomal protein L36E 2 3 3 3 -----------|||------------------------ 5 [U] COG5052 Protein involved in membrane traffic 2 3 3 3 -----------|||------------------------ 5 [J] COG5053 Translation initiation factor 4E (eIF-4E) 2 3 3 3 -----------|||------------------------ 5 [O] COG5054 Mitochondrial sulfhydryl oxidase involved in the biogenesis of cytosolic Fe/S proteins 2 3 3 3 -----------|||------------------------ 5 [L] COG5055 Recombination DNA repair protein (RAD52 pathway) 2 3 3 3 -----------|||------------------------ 5 [I] COG5056 Acyl-CoA cholesterol acyltransferase 2 3 3 3 -----------|||------------------------ 5 [DT] COG5057 Phosphotyrosyl phosphatase activator 2 3 3 3 -----------|||------------------------ 5 [U] COG5058 Protein transporter of the TRAM (translocating chain-associating membrane) superfamily, longevity assurance factor 2 3 3 3 -----------|||------------------------ 22 [Z] COG5059 Kinesin-like protein 2 3 3 3 -----------|||------------------------ 4 [OU] COG5061 Oxidoreductin, endoplasmic reticulum membrane-associated protein involved in disulfide bond formation 2 3 3 3 -----------|||------------------------ 4 [S] COG5062 Uncharacterized membrane protein 2 3 3 3 -----------|||------------------------ 4 [R] COG5063 CCCH-type Zn-finger protein 2 3 3 3 -----------|||------------------------ 4 [U] COG5064 Karyopherin (importin) alpha 2 3 3 3 -----------|||------------------------ 4 [P] COG5065 Protein involved in inorganic phosphate transport 2 3 3 3 -----------|||------------------------ 4 [U] COG5066 VAMP-associated protein involved in inositol metabolism 2 3 3 3 -----------|||------------------------ 4 [LD] COG5067 Protein kinase essential for the initiation of DNA replication 2 3 3 3 -----------|||------------------------ 8 [K] COG5068 Regulator of arginine metabolism and related MADS box-containing transcription factors 2 3 3 3 -----------|||------------------------ 4 [Z] COG5069 Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) 2 3 3 3 -----------|||------------------------ 5 [GOU] COG5070 Nucleotide-sugar transporter 2 3 3 3 -----------|||------------------------ 4 [O] COG5071 26S proteasome regulatory complex component 2 3 3 3 -----------|||------------------------ 4 [D] COG5072 Serine/threonine kinase of the haspin family 2 3 3 3 -----------|||------------------------ 5 [U] COG5073 Vacuolar import and degradation protein 2 3 3 3 -----------|||------------------------ 4 [U] COG5074 t-SNARE complex subunit, syntaxin 2 3 3 3 -----------|||------------------------ 4 [S] COG5075 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 21 [BK] COG5076 Transcription factor involved in chromatin remodeling, contains bromodomain 2 3 3 3 -----------|||------------------------ 4 [O] COG5077 Ubiquitin carboxyl-terminal hydrolase 2 3 3 3 -----------|||------------------------ 36 [O] COG5078 Ubiquitin-protein ligase 2 3 3 3 -----------|||------------------------ 4 [UD] COG5079 Nuclear protein export factor 2 3 3 3 -----------|||------------------------ 5 [U] COG5080 Rab GTPase interacting factor, Golgi membrane protein 2 3 3 3 -----------|||------------------------ 4 [S] COG5081 Predicted membrane protein 2 3 3 3 -----------|||------------------------ 9 [OU] COG5082 Arginine methyltransferase-interacting protein, contains RING Zn-finger 2 3 3 3 -----------|||------------------------ 10 [R] COG5084 Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin family Zn-finger proteins 2 3 3 3 -----------|||------------------------ 4 [S] COG5085 Predicted membrane protein 2 3 3 3 -----------|||------------------------ 3 [S] COG5086 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 3 [S] COG5087 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 3 [R] COG5088 Rad5p-binding protein 2 3 3 3 -----------|||------------------------ 3 [K] COG5090 Transcription initiation factor IIF, small subunit (RAP30) 2 3 3 3 -----------|||------------------------ 3 [R] COG5091 Suppressor of G2 allele of skp1 and related proteins 2 3 3 3 -----------|||------------------------ 3 [I] COG5092 N-myristoyl transferase 2 3 3 3 -----------|||------------------------ 3 [S] COG5093 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 3 [K] COG5094 Transcription initiation factor TFIID, subunit TAF9 (also component of histone acetyltransferase SAGA) 2 3 3 3 -----------|||------------------------ 3 [K] COG5095 Transcription initiation factor TFIID, subunit TAF6 (also component of histone acetyltransferase SAGA) 2 3 3 3 -----------|||------------------------ 10 [U] COG5096 Vesicle coat complex, various subunits 2 3 3 3 -----------|||------------------------ 3 [K] COG5097 RNA polymerase II transcriptional regulation mediator 2 3 3 3 -----------|||------------------------ 3 [BD] COG5098 Chromosome condensation complex Condensin, subunit D2 2 3 3 3 -----------|||------------------------ 13 [J] COG5099 RNA-binding protein of the Puf family, translational repressor 2 3 3 3 -----------|||------------------------ 3 [U] COG5100 Nuclear pore protein 2 3 3 3 -----------|||------------------------ 6 [U] COG5101 Nuclear transport receptor CRM1/MSN5 (importin beta superfamily) 2 3 3 3 -----------|||------------------------ 3 [U] COG5102 Membrane protein involved in ER to Golgi transport 2 3 3 3 -----------|||------------------------ 3 [DK] COG5103 Cell division control protein, negative regulator of transcription 2 3 3 3 -----------|||------------------------ 3 [A] COG5104 Splicing factor 2 3 3 3 -----------|||------------------------ 3 [D] COG5105 Mitotic inducer, protein phosphatase 2 3 3 3 -----------|||------------------------ 3 [S] COG5106 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 3 [A] COG5107 Pre-mRNA 3'-end processing (cleavage and polyadenylation) factor 2 3 3 3 -----------||-----------------------|- 3 [K] COG5108 Mitochondrial DNA-directed RNA polymerase 2 3 3 3 -----------|||------------------------ 3 [R] COG5109 Uncharacterized conserved protein, contains RING Zn-finger 2 3 3 3 -----------|||------------------------ 3 [O] COG5110 26S proteasome regulatory complex component 2 3 3 3 -----------|||------------------------ 3 [K] COG5111 DNA-directed RNA polymerase III, subunit C34 2 3 3 3 -----------|||------------------------ 3 [R] COG5112 U1-like Zn-finger-containing protein 2 3 3 3 -----------|||------------------------ 3 [O] COG5113 Ubiquitin fusion degradation protein 2 2 3 3 3 -----------|||------------------------ 3 [B] COG5114 Histone acetyltransferase complex SAGA/ADA, subunit ADA2 2 3 3 3 -----------|||------------------------ 3 [O] COG5116 26S proteasome regulatory complex component 2 3 3 3 -----------|||------------------------ 3 [JU] COG5117 Protein involved in the nuclear export of pre-ribosomes 2 3 3 3 -----------|||------------------------ 3 [K] COG5118 Transcription initiation factor TFIIIB, Bdp1 subunit 2 3 3 3 -----------||---|--------------------- 3 [R] COG5119 Uncharacterized protein, contains ParB-like nuclease domain 2 3 3 3 -----------|||------------------------ 3 [U] COG5120 Membrane protein involved in Golgi transport 2 3 3 3 -----------|||------------------------ 3 [U] COG5122 Transport protein particle (TRAPP) complex subunit 2 3 3 3 -----------|||------------------------ 3 [K] COG5123 Transcription initiation factor IIA, gamma subunit 2 3 3 3 -----------|||------------------------ 3 [DR] COG5124 Protein predicted to be involved in meiotic recombination 2 3 3 3 -----------|||------------------------ 3 [S] COG5125 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 3 [C] COG5127 Vacuolar H+-ATPase V1 sector, subunit C 2 3 3 3 -----------|||------------------------ 3 [U] COG5128 Transport protein particle (TRAPP) complex subunit 2 3 3 3 -----------|||------------------------ 3 [R] COG5129 Nuclear protein with HMG-like acidic region 2 3 3 3 -----------|||------------------------ 3 [UT] COG5130 Prenylated rab acceptor 1 and related proteins 2 3 3 3 -----------|||------------------------ 3 [KD] COG5132 Cell cycle control protein, G10 family 2 3 3 3 -----------|||------------------------ 3 [S] COG5133 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 3 [S] COG5134 Uncharacterized conserved protein 2 3 3 3 -----------||---|--------------------- 3 [S] COG5135 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 3 [A] COG5136 U1 snRNP-specific protein C 2 3 3 3 -----------|||------------------------ 3 [KB] COG5137 Histone chaperone involved in gene silencing 2 3 3 3 -----------|||------------------------ 3 [S] COG5138 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 3 [S] COG5139 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 3 [O] COG5140 Ubiquitin fusion-degradation protein 2 3 3 3 -----------|||------------------------ 3 [R] COG5141 PHD zinc finger-containing protein 2 3 3 3 -----------|||------------------------ 3 [L] COG5142 Oxidation resistance protein 2 3 3 3 -----------|||------------------------ 10 [U] COG5143 Synaptobrevin/VAMP-like protein 2 3 3 3 -----------|||------------------------ 3 [KL] COG5144 RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB2 2 3 3 3 -----------|||------------------------ 3 [L] COG5145 DNA excision repair protein 2 3 3 3 -----------||-----------|------------- 3 [H] COG5146 Pantothenate kinase, acetyl-CoA regulated 2 3 3 3 -----------|||------------------------ 10 [KAD] COG5147 Myb superfamily proteins, including transcription factors and mRNA splicing factors 2 3 3 3 -----------|||------------------------ 3 [O] COG5148 26S proteasome regulatory complex, subunit RPN10/PSMD4 2 3 3 3 -----------|||------------------------ 3 [K] COG5149 Transcription initiation factor IIA, large chain 2 3 3 3 -----------|||------------------------ 3 [K] COG5150 Class 2 transcription repressor NC2, beta subunit (Dr1) 2 3 3 3 -----------|||------------------------ 3 [KL] COG5151 RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit SSL1 2 3 3 3 -----------|||------------------------ 3 [R] COG5152 Uncharacterized conserved protein, contains RING and CCCH-type Zn-fingers 2 3 3 3 -----------|||------------------------ 3 [UI] COG5153 Putative lipase essential for disintegration of autophagic bodies inside the vacuole 2 3 3 3 -----------|||------------------------ 3 [J] COG5154 RNA-binding protein required for 60S ribosomal subunit biogenesis 2 3 3 3 -----------|||------------------------ 3 [DO] COG5155 Separase, a protease involved in sister chromatid separation 2 3 3 3 -----------|||------------------------ 3 [DO] COG5156 Anaphase-promoting complex (APC), subunit 10 2 3 3 3 -----------|||------------------------ 3 [K] COG5157 RNA polymerase II assessory factor 2 3 3 3 -----------|||------------------------ 11 [U] COG5158 Proteins involved in synaptic transmission and general secretion, Sec1 family 2 3 3 3 -----------|||------------------------ 3 [O] COG5159 26S proteasome regulatory complex component 2 3 3 3 -----------|||------------------------ 5 [O] COG5160 Protease, Ulp1 family 2 3 3 3 -----------|||------------------------ 3 [A] COG5161 Pre-mRNA cleavage and polyadenylation specificity factor 2 3 3 3 -----------|||------------------------ 3 [K] COG5162 Transcription initiation factor TFIID, subunit TAF10 (also component of histone acetyltransferase SAGA) 2 3 3 3 -----------|||------------------------ 3 [J] COG5163 Protein required for biogenesis of the 60S ribosomal subunit 2 3 3 3 -----------|||------------------------ 3 [K] COG5164 Transcription elongation factor 2 3 3 3 -----------|||------------------------ 3 [KLB] COG5165 Nucleosome-binding factor SPN, POB3 subunit 2 3 3 3 -----------|||------------------------ 3 [S] COG5166 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 3 [U] COG5167 Protein involved in vacuole import and degradation 2 3 3 3 -----------|||------------------------ 10 [K] COG5169 Heat shock transcription factor 2 3 3 3 -----------|||------------------------ 3 [T] COG5170 Serine/threonine protein phosphatase 2A, regulatory subunit 2 3 3 3 -----------|||------------------------ 3 [U] COG5171 Ran GTPase-activating protein (Ran-binding protein) 2 3 3 3 -----------|||------------------------ 3 [U] COG5173 Exocyst complex subunit SEC6 2 3 3 3 -----------|||------------------------ 3 [K] COG5174 Transcription initiation factor IIE, beta subunit 2 3 3 3 -----------|||------------------------ 3 [K] COG5175 Transcriptional repressor 2 3 3 3 -----------|||------------------------ 3 [A] COG5176 Splicing factor (branch point binding protein) 2 3 3 3 -----------|||------------------------ 3 [S] COG5177 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 3 [A] COG5178 U5 snRNP spliceosome subunit 2 3 3 3 -----------|||------------------------ 3 [K] COG5179 Transcription initiation factor TFIID, subunit TAF1 2 3 3 3 -----------|||------------------------ 3 [A] COG5180 Protein interacting with poly(A)-binding protein 2 3 3 3 -----------|||------------------------ 3 [A] COG5181 U2 snRNP spliceosome subunit 2 3 3 3 -----------|||------------------------ 3 [A] COG5182 Splicing factor 3b, subunit 2 2 3 3 3 -----------|||------------------------ 3 [A] COG5183 Protein involved in mRNA turnover and stability 2 3 3 3 -----------|||------------------------ 3 [D] COG5185 Protein involved in chromosome segregation, interacts with SMC proteins 2 3 3 3 -----------|||------------------------ 3 [A] COG5186 Poly(A) polymerase 2 3 3 3 -----------|||------------------------ 3 [O] COG5187 26S proteasome regulatory complex component, contains PCI domain 2 3 3 3 -----------|||------------------------ 3 [A] COG5188 Splicing factor 3a, subunit 3 2 3 3 3 -----------|||------------------------ 3 [KD] COG5189 Putative transcriptional repressor regulating G2/M transition 2 3 3 3 -----------|||------------------------ 12 [K] COG5190 TFIIF-interacting CTD phosphatases, including NLI-interacting factor 2 3 3 3 -----------|||------------------------ 3 [R] COG5191 Uncharacterized conserved protein, contains HAT (Half-A-TPR) repeat 2 3 3 3 -----------|||------------------------ 3 [J] COG5192 GTP-binding protein required for 40S ribosome biogenesis 2 3 3 3 -----------|||------------------------ 6 [OJ] COG5193 La protein, small RNA-binding pol III transcript stabilizing protein and related La-motif-containing proteins involved in translation 2 3 3 3 -----------|||------------------------ 5 [OD] COG5194 Component of SCF ubiquitin ligase and anaphase-promoting complex 2 3 3 3 -----------|||------------------------ 3 [S] COG5195 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 3 [U] COG5196 ER lumen protein retaining receptor 2 3 3 3 -----------|||------------------------ 3 [S] COG5197 Predicted membrane protein 2 3 3 3 -----------|||------------------------ 3 [R] COG5198 Protein tyrosine phosphatase-like protein (contains Pro instead of catalytic Arg) 2 3 3 3 -----------|||------------------------ 3 [Z] COG5199 Calponin 2 3 3 3 -----------|||------------------------ 3 [A] COG5200 U1 snRNP component, mediates U1 snRNP association with cap-binding complex 2 3 3 3 -----------|||------------------------ 3 [O] COG5201 SCF ubiquitin ligase, SKP1 component 2 3 3 3 -----------|||------------------------ 3 [S] COG5202 Predicted membrane protein 2 3 3 3 -----------|||------------------------ 3 [K] COG5204 Transcription elongation factor SPT4 2 3 3 3 -----------|||------------------------ 3 [O] COG5206 Glycosylphosphatidylinositol transamidase (GPIT), subunit GPI8 2 3 3 3 -----------|||------------------------ 3 [O] COG5207 Isopeptidase T 2 3 3 3 -----------|||------------------------ 3 [K] COG5208 CCAAT-binding factor, subunit C 2 3 3 3 -----------|||------------------------ 3 [R] COG5209 Uncharacterized protein involved in cell differentiation/sexual development 2 3 3 3 -----------|||------------------------ 25 [R] COG5210 GTPase-activating protein 2 3 3 3 -----------|||------------------------ 3 [K] COG5211 RNA polymerase II-interacting protein involved in transcription start site selection 2 3 3 3 -----------||---------------|--------- 3 [T] COG5212 Low-affinity cAMP phosphodiesterase 2 3 3 3 -----------|||------------------------ 3 [A] COG5213 Polyadenylation factor I complex, subunit FIP1 2 3 3 3 -----------|||------------------------ 3 [L] COG5214 DNA polymerase alpha-primase complex, polymerase-associated subunit B 2 3 3 3 -----------|||------------------------ 3 [U] COG5215 Karyopherin (importin) beta 2 3 3 3 -----------|||------------------------ 3 [S] COG5216 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 3 [DZ] COG5217 Microtubule-binding protein involved in cell cycle control 2 3 3 3 -----------|||------------------------ 3 [BD] COG5218 Chromosome condensation complex Condensin, subunit G 2 3 3 3 -----------|||------------------------ 3 [R] COG5219 Uncharacterized conserved protein, contains RING Zn-finger 2 3 3 3 -----------|||------------------------ 3 [DKL] COG5220 Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB3 2 3 3 3 -----------|||------------------------ 3 [K] COG5221 Dopey and related predicted leucine zipper transcription factors 2 3 3 3 -----------|||------------------------ 3 [R] COG5222 Uncharacterized conserved protein, contains RING Zn-finger 2 3 3 3 -----------|||------------------------ 3 [S] COG5223 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 3 [K] COG5224 CCAAT-binding factor, subunit B 2 3 3 3 -----------|||------------------------ 3 [J] COG5225 Uncharacterized protein involved in ribosome biogenesis 2 3 3 3 -----------|||------------------------ 3 [A] COG5226 mRNA capping enzyme, guanylyltransferase (alpha) subunit 2 3 3 3 -----------|||------------------------ 3 [O] COG5227 Ubiquitin-like protein (sentrin) 2 3 3 3 -----------|||------------------------ 3 [A] COG5228 mRNA deadenylase subunit 2 3 3 3 -----------|||------------------------ 3 [BD] COG5229 Chromosome condensation complex Condensin, subunit H 2 3 3 3 -----------|||------------------------ 3 [S] COG5230 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 3 [C] COG5231 Vacuolar H+-ATPase V1 sector, subunit H 2 3 3 3 -----------|||------------------------ 3 [U] COG5232 Preprotein translocase subunit Sec62 2 3 3 3 -----------|||------------------------ 3 [U] COG5233 Peripheral Golgi membrane protein 2 3 3 3 -----------|||------------------------ 3 [OZ] COG5234 Beta-tubulin folding cofactor D 2 3 3 3 -----------|||------------------------ 3 [L] COG5235 Single-stranded DNA-binding replication protein A (RPA), medium (30 kD) subunit 2 3 3 3 -----------|||------------------------ 3 [R] COG5236 Uncharacterized conserved protein, contains RING Zn-finger 2 3 3 3 -----------|||------------------------ 3 [S] COG5237 Predicted membrane protein 2 3 3 3 -----------|||------------------------ 3 [TA] COG5238 Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport 2 3 3 3 -----------|||------------------------ 7 [A] COG5239 mRNA deadenylase, exonuclease subunit and related nucleases 2 3 3 3 -----------|||------------------------ 3 [U] COG5240 Vesicle coat complex COPI, gamma subunit 2 3 3 3 -----------|||------------------------ 3 [L] COG5241 Nucleotide excision repair endonuclease NEF1, RAD10 subunit 2 3 3 3 -----------|||------------------------ 3 [KL] COG5242 RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB4 2 3 3 3 -----------|||------------------------ 3 [O] COG5243 HRD ubiquitin ligase complex, ER membrane component 2 3 3 3 -----------|||------------------------ 3 [D] COG5244 Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B 2 3 3 3 -----------|||------------------------ 3 [Z] COG5245 Dynein, heavy chain 2 3 3 3 -----------|||------------------------ 3 [A] COG5246 Splicing factor 3a, subunit 2 2 3 3 3 -----------|||------------------------ 3 [K] COG5247 Class 2 transcription repressor NC2, alpha subunit (DRAP1 homolog) 2 3 3 3 -----------|||------------------------ 3 [K] COG5248 Transcription initiation factor TFIID, subunit TAF13 2 3 3 3 -----------|||------------------------ 3 [U] COG5249 Golgi protein involved in Golgi-to-ER retrieval 2 3 3 3 -----------|||------------------------ 3 [K] COG5250 RNA polymerase II, fourth largest subunit 2 3 3 3 -----------|||------------------------ 3 [K] COG5251 Transcription initiation factor TFIID, subunit TAF11 2 3 3 3 -----------|||------------------------ 3 [R] COG5252 Uncharacterized conserved protein, contains CCCH-type Zn-finger protein 2 3 3 3 -----------|||------------------------ 5 [T] COG5253 Phosphatidylinositol-4-phosphate 5-kinase 2 3 3 3 -----------|||------------------------ 3 [S] COG5254 Predicted membrane protein 2 2 3 4 -------------------------|---------||- 4 [S] COG5255 Uncharacterized protein conserved in bacteria 2 3 3 3 -----------|||------------------------ 5 [BK] COG5259 RSC chromatin remodeling complex subunit RSC8 2 3 3 3 -----------|||------------------------ 9 [L] COG5260 DNA polymerase sigma 2 3 3 3 -----------|||------------------------ 4 [DT] COG5261 Protein involved in regulation of cellular morphogenesis/cytokinesis 2 3 3 3 -----------|||------------------------ 7 [B] COG5262 Histone H2A 2 3 3 3 -----------|||------------------------ 8 [O] COG5264 Vacuolar transporter chaperone 1 2 3 4 --------------------------------|--||- 5 [S] COG5267 Uncharacterized protein conserved in bacteria 1 3 3 4 -----------------------------|--|---|- 4 [NU] COG5268 Type IV secretory pathway, TrbD component 2 3 3 3 -----------|||------------------------ 3 [JO] COG5269 Ribosome-associated chaperone zuotin 2 3 3 3 -----------|||------------------------ 3 [R] COG5271 AAA ATPase containing von Willebrand factor type A (vWA) domain 2 3 3 3 -----------|||------------------------ 22 [O] COG5272 Ubiquitin 2 3 3 3 -----------|||------------------------ 17 [R] COG5273 Uncharacterized protein containing DHHC-type Zn finger 2 3 3 3 -----------|||------------------------ 12 [CI] COG5274 Cytochrome b involved in lipid metabolism 2 3 3 3 -----------|||------------------------ 3 [R] COG5275 BRCT domain type II 3 3 3 3 --|------------|------------|--------- 4 [S] COG5276 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 23 [Z] COG5277 Actin and related proteins 2 3 3 3 -----------|||------------------------ 3 [K] COG5290 IkappaB kinase complex, IKAP component 2 3 3 3 -----------|||------------------------ 3 [S] COG5291 Predicted membrane protein 3 3 3 3 ----------------|-------|----|-------- 3 [S] COG5293 Uncharacterized protein conserved in bacteria 2 3 3 3 -----------|||------------------------ 3 [K] COG5296 Transcription factor involved in TATA site selection and in elongation by RNA polymerase II 2 3 3 4 ----------------------|------|--|----- 4 [G] COG5297 Cellobiohydrolase A (1,4-beta-cellobiosidase A) 1 2 3 3 ---------------------------||---|----- 4 [R] COG5301 Phage-related tail fibre protein 2 3 3 7 ----------------------|-----|-------|- 7 [R] COG5302 Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid 2 2 3 3 -----------------|-----------------|-| 4 [S] COG5304 Uncharacterized protein conserved in bacteria 2 3 3 3 -----------|||------------------------ 4 [U] COG5308 Nuclear pore complex subunit 2 3 3 3 -----------||--------------|---------- 6 [G] COG5309 Exo-beta-1,3-glucanase 1 3 3 4 -----------------------------|--|---|- 6 [U] COG5314 Conjugal transfer/entry exclusion protein 3 3 3 3 --|---------------|----------------|-- 6 [S] COG5316 Uncharacterized conserved protein 1 2 3 6 --------------------------------|--||- 6 [S] COG5319 Uncharacterized protein conserved in bacteria 2 2 3 4 --|--------------------------------||- 4 [S] COG5323 Uncharacterized conserved protein 2 3 3 3 -----------||------|------------------ 3 [S] COG5324 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 6 [U] COG5325 t-SNARE complex subunit, syntaxin 2 3 3 3 -----------|||------------------------ 11 [T] COG5329 Phosphoinositide polyphosphatase (Sac family) 2 3 3 3 -----------|||------------------------ 9 [DKL] COG5333 Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, cyclin H subunit 1 1 3 7 -----------------------------------||| 7 [S] COG5336 Uncharacterized protein conserved in bacteria 3 3 3 3 --|-------------------|-|------------- 4 [M] COG5337 Spore coat assembly protein 2 3 3 5 ---|-|----------------|--------------- 7 [K] COG5340 Predicted transcriptional regulator 2 3 3 5 ----------------|----------------|---| 5 [S] COG5346 Predicted membrane protein 2 3 3 3 -----------|||------------------------ 14 [U] COG5347 GTPase-activating protein that regulates ARFs (ADP-ribosylation factors), involved in ARF-mediated vesicular transport 2 3 3 3 -----------|||------------------------ 5 [R] COG5354 Uncharacterized protein, contains Trp-Asp (WD) repeat 2 3 3 3 -----------|||------------------------ 4 [R] COG5366 Protein involved in propagation of M2 dsRNA satellite of L-A virus 2 3 3 3 -----------|||------------------------ 3 [S] COG5369 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 5 [GO] COG5371 Golgi nucleoside diphosphatase 2 3 3 3 -----------|||------------------------ 5 [S] COG5374 Uncharacterized conserved protein 1 1 3 7 -----------------------------------||| 8 [S] COG5375 Uncharacterized protein conserved in bacteria 2 3 3 3 -|---|----|--------------------------- 3 [R] COG5378 Predicted nucleotide-binding protein 1 1 3 3 ---------------------------|-||------- 3 [O] COG5380 Lipase chaperone 2 3 3 9 ----------------------|-----|-------|- 11 [S] COG5383 Uncharacterized protein conserved in bacteria 2 3 3 3 -----------|||------------------------ 3 [J] COG5384 U3 small nucleolar ribonucleoprotein component 2 3 3 3 -----------|||------------------------ 13 [UR] COG5391 Phox homology (PX) domain protein 1 2 3 7 ---------------------------||---|----- 7 [S] COG5393 Predicted membrane protein 1 2 3 5 --------------------------------|--||- 5 [S] COG5394 Uncharacterized protein conserved in bacteria 1 1 3 3 --------|||--------------------------- 3 [S] COG5399 Uncharacterized protein conserved in archaea 2 3 3 3 -----------|||------------------------ 3 [KLB] COG5406 Nucleosome binding factor SPN, SPT16 subunit 2 3 3 3 -----------|||------------------------ 3 [U] COG5407 Preprotein translocase subunit Sec63 2 3 3 3 -----------|||------------------------ 8 [T] COG5408 SPX domain-containing protein 2 3 3 3 -----------|||------------------------ 6 [T] COG5409 EXS domain-containing protein 2 3 3 4 ------------------------|----|-------| 6 [S] COG5410 Uncharacterized protein conserved in bacteria 2 3 3 3 -----------|||------------------------ 8 [T] COG5411 Phosphatidylinositol 5-phosphate phosphatase 2 3 3 4 ----------------||-------------|------ 4 [S] COG5413 Uncharacterized integral membrane protein 2 3 3 3 -----------|||------------------------ 3 [K] COG5414 TATA-binding protein-associated factor 2 3 3 3 -----------|||------------------------ 3 [R] COG5415 Predicted integral membrane metal-binding protein 1 3 3 4 -||--|-------------------------------- 4 [S] COG5418 Predicted secreted protein 2 3 3 3 --|-|-----------|--------------------- 24 [L] COG5421 Transposase 2 3 3 3 -----------|||------------------------ 5 [T] COG5422 RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases 1 3 3 4 --|--||------------------------------- 6 [S] COG5423 Predicted metal-binding protein 1 3 3 3 --||--|------------------------------- 4 [S] COG5427 Uncharacterized membrane protein 1 2 3 6 --------------------------------|--||- 7 [S] COG5429 Uncharacterized secreted protein 2 2 3 3 ------|--||--------------------------- 3 [S] COG5431 Uncharacterized metal-binding protein 2 3 3 3 -----------|||------------------------ 3 [T] COG5432 RING-finger-containing E3 ubiquitin ligase 1 2 3 6 ---------------------------||---|----- 9 [S] COG5435 Uncharacterized conserved protein 2 2 3 5 ------------------------|----------||- 5 [S] COG5437 Predicted secreted protein 1 2 3 5 ---------------------------||---|----- 8 [S] COG5445 Predicted secreted protein 1 1 3 4 -----------------------------------||| 4 [S] COG5448 Uncharacterized conserved protein 1 1 3 4 -----------------------------------||| 4 [S] COG5449 Uncharacterized conserved protein 2 2 3 5 ----------------------|------------||- 16 [K] COG5450 Transcription regulator of the Arc/MetJ class 1 2 3 9 ---------------------------||-------|- 20 [S] COG5457 Uncharacterized conserved small protein 2 3 3 4 -----------||-----------------------|- 4 [J] COG5459 Predicted rRNA methylase 1 2 3 7 ----------------------------|------||- 11 [S] COG5463 Predicted integral membrane protein 2 2 3 7 --------------------|--------------||- 7 [S] COG5465 Uncharacterized conserved protein 2 3 3 4 ----------------||------------------|- 8 [S] COG5469 Predicted metal-binding protein 2 3 3 6 --|-----------------------------|---|- 11 [S] COG5470 Uncharacterized conserved protein 1 2 3 5 ----------------------------||------|- 7 [S] COG5471 Uncharacterized conserved protein 1 3 3 3 ----------------------------|---|-|--- 4 [S] COG5472 Predicted small integral membrane protein 2 3 3 3 ----------------||------------|------- 3 [S] COG5474 Uncharacterized conserved protein 3 3 3 6 --|---------------|---|--------------- 15 [M] COG5479 Uncharacterized protein potentially involved in peptidoglycan biosynthesis 2 2 3 3 --|-----|-|--------------------------- 3 [S] COG5483 Uncharacterized conserved protein 1 2 3 6 --------------------------------|--||- 6 [S] COG5488 Integral membrane protein 1 2 3 5 --------------------------------|--||- 9 [S] COG5489 Uncharacterized conserved protein 2 3 3 7 -----------------------||---|--------- 38 [N] COG5492 Bacterial surface proteins containing Ig-like domains 1 1 3 3 --------|||--------------------------- 5 [S] COG5493 Uncharacterized conserved protein containing a coiled-coil domain 1 1 3 3 --------|||--------------------------- 3 [O] COG5494 Predicted thioredoxin/glutaredoxin 3 3 3 5 ---------------|------|---------|----- 5 [S] COG5495 Uncharacterized conserved protein 3 3 3 5 ------------------|--|--------------|- 7 [S] COG5497 Predicted secreted protein 2 3 3 3 -----------||-----------|------------- 5 [M] COG5498 Predicted glycosyl hydrolase 2 3 3 7 ----------------|-----------|-------|- 7 [K] COG5499 Predicted transcription regulator containing HTH domain 2 3 3 3 --------------|-----------------|---|- 3 [S] COG5501 Predicted secreted protein 3 3 3 4 --------------|-|-------------------|- 7 [S] COG5502 Uncharacterized conserved protein 3 3 3 4 -----|-------------|----|------------- 4 [S] COG5505 Predicted integral membrane protein 1 2 3 5 ----------------------------||--|----- 22 [R] COG5511 Bacteriophage capsid protein 3 3 3 3 --|--------------------|---|---------- 7 [S] COG5513 Predicted secreted protein 2 3 3 4 ------------------------|---|---|----- 5 [R] COG5518 Bacteriophage capsid portal protein 1 2 3 5 -----------------------|||------------ 6 [S] COG5523 Predicted integral membrane protein 2 2 3 3 ----------------|------------------||- 3 [S] COG5526 Uncharacterized conserved protein 2 3 3 4 -----------------------||--------|---- 4 [L] COG5527 Protein involved in initiation of plasmid replication 1 2 3 3 ---------------------------|-------||- 3 [S] COG5528 Predicted integral membrane protein 2 3 3 3 --|-------------------------|------|-- 3 [R] COG5529 Pyocin large subunit 1 2 3 3 ----------------------------||---|---- 3 [S] COG5532 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 4 [O] COG5533 Ubiquitin C-terminal hydrolase 2 3 3 3 ------------------|-------------|---|- 4 [L] COG5534 Plasmid replication initiator protein 2 3 3 3 -----------|||------------------------ 5 [L] COG5535 DNA repair protein RAD4 2 3 3 3 -----------|||------------------------ 5 [O] COG5536 Protein prenyltransferase, alpha subunit 2 3 3 3 -----------|||------------------------ 4 [D] COG5537 Cohesin 2 3 3 3 -----------|||------------------------ 3 [U] COG5538 Preprotein translocase subunit Sec66 2 3 3 3 -----------|||------------------------ 5 [O] COG5539 Predicted cysteine protease (OTU family) 2 3 3 3 -----------|||------------------------ 4 [O] COG5540 RING-finger-containing ubiquitin ligase 2 3 3 3 -----------|||------------------------ 3 [O] COG5541 Vesicle coat complex COPI, zeta subunit 2 3 3 3 -----------|||------------------------ 3 [S] COG5543 Uncharacterized conserved protein 1 2 3 7 ---------------------------||---|----- 7 [R] COG5544 Predicted periplasmic lipoprotein 3 3 3 3 ----------------|--------|---|-------- 4 [R] COG5545 Predicted P-loop ATPase and inactivated derivatives 2 3 3 3 -----------||---|--------------------- 3 [S] COG5548 Small integral membrane protein 2 2 3 3 --------||------|--------------------- 10 [O] COG5550 Predicted aspartyl protease 2 3 3 3 ----------------|----------|--------|- 3 [R] COG5553 Predicted metal-dependent enzyme of the double-stranded beta helix superfamily 2 3 3 6 ---|--|---------------------|--------- 7 [C] COG5557 Polysulphide reductase 2 3 3 3 ----|-|--|---------------------------- 9 [L] COG5558 Transposase 2 3 3 3 -----||----------|-------------------- 4 [S] COG5559 Uncharacterized conserved small protein 2 3 3 3 -----------|||------------------------ 4 [O] COG5560 Ubiquitin C-terminal hydrolase 1 3 3 3 -||---|------------------------------- 4 [S] COG5561 Predicted metal-binding protein 1 1 3 4 ----------------------------|-||------ 5 [S] COG5566 Uncharacterized conserved protein 1 2 3 6 ---------------------------||-------|- 6 [N] COG5567 Predicted small periplasmic lipoprotein 1 3 3 6 ----------------------------|---|---|- 7 [S] COG5569 Uncharacterized conserved protein 1 2 3 3 --------------------------------|--||- 3 [S] COG5572 Predicted integral membrane protein 2 3 3 3 -----------|||------------------------ 6 [O] COG5574 RING-finger-containing E3 ubiquitin ligase 2 3 3 3 -----------|||------------------------ 3 [L] COG5575 Origin recognition complex, subunit 2 2 3 3 3 -----------|||------------------------ 14 [K] COG5576 Homeodomain-containing transcription factor 2 3 3 3 -----------|||------------------------ 4 [O] COG5580 Activator of HSP90 ATPase 2 3 3 4 -----------------------||--|---------- 5 [S] COG5583 Uncharacterized small protein 1 2 3 3 ------------------------------|----||- 3 [S] COG5589 Uncharacterized conserved protein 1 3 3 3 ------------------------------|-|---|- 4 [S] COG5591 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 3 [J] COG5593 Nucleic-acid-binding protein possibly involved in ribosomal biogenesis 2 3 3 3 -----------|||------------------------ 8 [S] COG5594 Uncharacterized integral membrane protein 1 2 3 4 ------------------------------||-----| 5 [R] COG5595 Zn-ribbon-containing, possibly nucleic-acid-binding protein 2 3 3 3 -----------|||------------------------ 7 [O] COG5596 Mitochondrial import inner membrane translocase, subunit TIM22 2 3 3 3 -----------||-----------------------|- 5 [M] COG5597 Alpha-N-acetylglucosamine transferase 2 3 3 3 -----------|||------------------------ 6 [T] COG5599 Protein tyrosine phosphatase 2 3 3 3 -----------|||------------------------ 5 [L] COG5600 Transcription-associated recombination protein 2 3 3 3 -----------|||------------------------ 3 [K] COG5601 General negative regulator of transcription subunit 2 3 3 3 -----------|||------------------------ 5 [B] COG5602 Histone deacetylase complex, SIN3 component 2 3 3 3 -----------|||------------------------ 3 [N] COG5603 Subunit of TRAPP, an ER-Golgi tethering complex 2 3 3 3 -----------|||------------------------ 4 [S] COG5604 Uncharacterized conserved protein 2 2 3 5 ----------------|-----------||-------- 7 [S] COG5606 Uncharacterized conserved small protein 2 3 3 4 -----||--------------------|---------- 6 [S] COG5608 Conserved secreted protein 2 2 3 3 --------------|---------------------|| 3 [R] COG5611 Predicted nucleic-acid-binding protein, contains PIN domain 3 3 3 4 ----|-----|----------------|---------- 4 [S] COG5615 Predicted integral membrane protein 2 3 3 3 -----|-|---------------|-------------- 7 [S] COG5617 Predicted integral membrane protein 1 2 3 3 ---------------------------|-|------|- 3 [S] COG5619 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 3 [A] COG5623 Pre-mRNA cleavage and polyadenylation factor IA/II complex, subunit CLP1 2 3 3 3 -----------|||------------------------ 3 [K] COG5624 Transcription initiation factor TFIID, subunit TAF12 (also component of histone acetyltransferase SAGA) 2 3 3 3 ----------------||---------|---------- 3 [S] COG5626 Uncharacterized conserved small protein 2 3 3 3 -----------|||------------------------ 3 [L] COG5627 DNA repair protein MMS21 2 2 3 3 ------------------------|----------|-| 3 [R] COG5628 Predicted acetyltransferase 2 3 3 3 -----------|||------------------------ 3 [S] COG5629 Predicted metal-binding protein 2 3 3 3 -----------||----------------|-------- 3 [E] COG5630 Acetylglutamate synthase 1 1 3 8 ----------------------------|-||------ 8 [R] COG5633 Predicted periplasmic lipoprotein 3 3 3 3 ----------------|-------|-------|----- 3 [S] COG5634 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 3 [S] COG5636 Uncharacterized conserved protein, contains Zn-ribbon-like motif 2 3 3 3 ----------------|||------------------- 5 [S] COG5637 Predicted integral membrane protein 2 3 3 3 -----------|||------------------------ 3 [S] COG5638 Uncharacterized conserved protein 1 2 3 3 --------------------------------|--||- 5 [S] COG5639 Uncharacterized conserved small protein 2 3 3 3 -----------|||------------------------ 13 [K] COG5641 GATA Zn-finger-containing transcription factor 1 3 3 3 |-|----|------------------------------ 7 [R] COG5643 Protein containing a metal-binding domain shared with formylmethanofuran dehydrogenase subunit E 2 3 3 3 -----------|||------------------------ 3 [S] COG5644 Uncharacterized conserved protein 1 1 3 8 ---------------------------||--|------ 12 [R] COG5645 Predicted periplasmic lipoprotein 2 3 3 3 -----------|||------------------------ 6 [O] COG5647 Cullin, a subunit of E3 ubiquitin ligase 2 3 3 3 -----------|||------------------------ 10 [B] COG5648 Chromatin-associated proteins containing the HMG domain 2 3 3 7 ----|--|--------------|--------------- 10 [S] COG5650 Predicted integral membrane protein 3 3 3 6 -------------------|--|-----------|--- 145 [N] COG5651 PPE-repeat proteins 2 3 3 5 ----------------------|-----|-------|- 9 [S] COG5654 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 4 [O] COG5656 Importin, protein involved in nuclear import 2 3 3 3 -----------|||------------------------ 7 [D] COG5657 CAS/CSE protein involved in chromosome segregation 2 3 3 3 -----------------|--------------|---|- 18 [L] COG5659 FOG: Transposase 3 3 3 6 ---------------------||-|------------- 6 [S] COG5660 Predicted integral membrane protein 2 3 3 4 -----------------------||-----------|- 4 [S] COG5663 Uncharacterized conserved protein 2 3 3 3 -----------|||------------------------ 4 [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit 2 3 3 4 ----|-|--|---------------------------- 4 [S] COG5666 Uncharacterized conserved protein