y a o g aaaaaaaaaaaaaaaaaaaaaaaaaaaa 3 5 7 11 ---------------|-----||-||-- 11 [S] COG0700 Uncharacterized membrane protein 3 5 11 20 ------------|----|------||-| 22 [M] COG0729 Outer membrane protein 2 5 7 12 --------------||--------|-|| 14 [P] COG0748 Putative heme iron utilization protein 4 5 7 12 ---------|||------|-----|--- 13 [O] COG1025 Secreted/periplasmic Zn-dependent peptidases, insulinase-like 1 5 5 5 |||---||-------------------- 12 [C] COG1029 Formylmethanofuran dehydrogenase subunit B 1 5 5 5 |||---||-------------------- 8 [C] COG1036 Archaeal flavoproteins 3 5 5 7 --|------------|--------|||- 9 [M] COG1083 CMP-N-acetylneuraminic acid synthetase 2 5 5 5 ||----||------|------------- 7 [R] COG1099 Predicted metal-dependent hydrolases with the TIM-barrel fold 1 5 5 5 |||---||-------------------- 6 [R] COG1103 Archaea-specific pyridoxal phosphate-dependent enzymes 3 5 7 19 --------------------|||-|--| 77 [E] COG1113 Gamma-aminobutyrate permease and related permeases 1 5 5 5 |||---||-------------------- 10 [C] COG1152 CO dehydrogenase/acetyl-CoA synthase alpha subunit 1 5 5 5 |||---||-------------------- 9 [C] COG1153 Formylmethanofuran dehydrogenase subunit D 1 5 5 5 |||---||-------------------- 5 [R] COG1223 Predicted ATPase (AAA+ superfamily) 1 5 5 5 |||---||-------------------- 7 [C] COG1229 Formylmethanofuran dehydrogenase subunit A 1 5 5 6 ||-|-||--------------------- 6 [S] COG1255 Uncharacterized protein conserved in archaea 4 5 5 9 ------|-------------|-|-|--| 18 [S] COG1273 Uncharacterized conserved protein 4 5 7 13 -----------------|-|--|-|--| 19 [S] COG1288 Predicted membrane protein 4 5 5 6 -------------|-----|-||-|--- 6 [L] COG1315 Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain 5 5 7 16 ----------------|--||-|----| 17 [K] COG1329 Transcriptional regulators, similar to M. xanthus CarD 4 5 9 18 ------------------|||---||-- 18 [L] COG1330 Exonuclease V gamma subunit 3 5 10 22 ------------|-------|---||-| 22 [OT] COG1391 Glutamine synthetase adenylyltransferase 4 5 5 6 -------------|-----|-||-|--- 6 [N] COG1406 Predicted inhibitor of MCP methylation, homolog of CheC 1 5 5 5 |||---||-------------------- 5 [R] COG1411 Uncharacterized protein related to proFAR isomerase (HisA) 4 5 6 12 ----------------|--|--||-|-- 16 [F] COG1428 Deoxynucleoside kinases 1 5 5 5 |||---||-------------------- 6 [C] COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein) 3 5 6 14 -------------|-------||-|--| 37 [G] COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases 1 5 5 6 |-|--|||-------------------- 7 [S] COG1504 Uncharacterized conserved protein 3 5 5 8 -|---|----------------|--|-| 11 [K] COG1510 Predicted transcriptional regulators 4 5 6 14 |---------------|---|||----- 27 [S] COG1511 Predicted membrane protein 3 5 6 8 ------------|-||--------||-- 8 [P] COG1513 Cyanate lyase 3 5 6 6 -|--||--|---|--------------- 12 [L] COG1517 Uncharacterized protein predicted to be involved in DNA repair 1 5 5 5 |||---||-------------------- 5 [KG] COG1548 Predicted transcriptional regulator/sugar kinase 4 5 5 9 -------------|--|---|||----- 9 [S] COG1550 Uncharacterized protein conserved in bacteria 3 5 11 21 ------------|---------|-||-| 66 [V] COG1566 Multidrug resistance efflux pump 2 5 5 6 |-|--||-------|------------- 9 [S] COG1572 Uncharacterized conserved protein 1 5 5 5 |||---||-------------------- 7 [C] COG1614 CO dehydrogenase/acetyl-CoA synthase beta subunit 4 5 5 8 ------|-------||----||------ 11 [S] COG1615 Uncharacterized conserved protein 4 5 5 8 -------------|---|--|||----- 8 [R] COG1623 Predicted nucleic-acid-binding protein (contains the HHH domain) 5 5 6 9 --|-----|---|--|--------|--- 46 [L] COG1662 Transposase and inactivated derivatives, IS1 family 3 5 8 19 -------------------|-||-|--| 19 [S] COG1671 Uncharacterized protein conserved in bacteria 2 5 6 7 ||---||-|------------------- 11 [S] COG1673 Uncharacterized protein conserved in archaea 1 5 5 5 |||---||-------------------- 6 [S] COG1693 Uncharacterized protein conserved in archaea 4 5 5 9 -------------|-----|-||---|- 11 [S] COG1699 Uncharacterized protein conserved in bacteria 3 5 8 15 -------------|--------|-||-| 27 [NU] COG1705 Muramidase (flagellum-specific) 2 5 7 8 -||--||-|------------------- 9 [R] COG1750 Archaeal serine proteases 2 5 5 5 |||---|------|-------------- 5 [S] COG1751 Uncharacterized conserved protein 4 5 6 12 ----------------|---|-|-||-- 12 [S] COG1755 Uncharacterized protein conserved in bacteria 4 5 10 21 --------------|-----|-|-|--| 23 [E] COG1770 Protease II 1 5 5 6 -||--|||-------------------- 6 [S] COG1772 Uncharacterized protein conserved in archaea 5 5 5 6 -------------|-||-----|---|- 6 [V] COG1787 Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes 3 5 11 23 ----------------|-----|-||-| 24 [S] COG1806 Uncharacterized protein conserved in bacteria 3 5 5 5 ||-----|------------|-|----- 5 [S] COG1809 Uncharacterized conserved protein 1 5 5 5 |||---||-------------------- 12 [S] COG1810 Uncharacterized protein conserved in archaea 2 5 5 6 |||--|--|------------------- 8 [S] COG1817 Uncharacterized protein conserved in archaea 1 5 5 5 |||---||-------------------- 5 [R] COG1821 Predicted ATP-utilizing enzyme (ATP-grasp superfamily) 1 5 5 6 |||--|-|-------------------- 6 [S] COG1844 Uncharacterized protein conserved in archaea 4 5 8 15 -------------|------|-|||--- 16 [G] COG1869 ABC-type ribose transport system, auxiliary component 1 5 5 5 |||---||-------------------- 7 [C] COG1880 CO dehydrogenase/acetyl-CoA synthase epsilon subunit 1 5 5 5 |||---||-------------------- 5 [S] COG1891 Uncharacterized protein conserved in archaea 2 5 5 5 -||--||------|-------------- 6 [S] COG1895 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN 1 5 5 5 |||---||-------------------- 9 [C] COG1908 Coenzyme F420-reducing hydrogenase, delta subunit 1 5 5 5 |||---||-------------------- 5 [C] COG1927 Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin dehydrogenase 1 5 5 6 -||--|||-------------------- 6 [S] COG1935 Uncharacterized conserved protein 4 5 10 21 ---------|-|--------|---|--| 25 [I] COG1946 Acyl-CoA thioesterase 3 5 10 20 ---------||---------|---||-- 20 [A] COG1949 Oligoribonuclease (3'->5' exoribonuclease) 4 5 5 10 -------------|---|---||-|--- 12 [K] COG1954 Glycerol-3-phosphate responsive antiterminator (mRNA-binding) 1 5 5 5 |||---||-------------------- 6 [H] COG1962 Tetrahydromethanopterin S-methyltransferase, subunit H 3 5 8 16 --------------|-------|-|-|| 29 [F] COG1972 Nucleoside permease 1 5 5 5 |||---||-------------------- 5 [J] COG2024 Phenylalanyl-tRNA synthetase alpha subunit (archaeal type) 1 5 5 6 |||--|-|-------------------- 6 [S] COG2029 Uncharacterized conserved protein 1 5 5 5 |||---||-------------------- 8 [C] COG2037 Formylmethanofuran:tetrahydromethanopterin formyltransferase 1 5 5 5 |||---||-------------------- 14 [S] COG2043 Uncharacterized protein conserved in archaea 3 5 5 6 -------------|||-----||----- 6 [S] COG2052 Uncharacterized protein conserved in bacteria 1 5 5 5 |||---||-------------------- 5 [R] COG2054 Uncharacterized archaeal kinase related to aspartokinases, uridylate kinases 3 5 7 13 -----------------|----|-|||- 15 [R] COG2056 Predicted permease 1 5 5 5 |||---||-------------------- 5 [E] COG2061 ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase 1 5 5 5 |||---||-------------------- 6 [C] COG2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein) 1 5 5 6 ||---|||-------------------- 6 [S] COG2083 Uncharacterized protein conserved in archaea 4 5 5 8 ------|----------|-|-||----- 9 [M] COG2088 Uncharacterized protein, involved in the regulation of septum location 2 5 6 7 -|---||||------------------- 7 [R] COG2100 Predicted Fe-S oxidoreductase 3 5 7 8 -|---||-|---|--------------- 8 [T] COG2112 Predicted Ser/Thr protein kinase 1 5 5 6 ||||-|---------------------- 6 [J] COG2117 Predicted subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain 2 5 5 5 |||----|-------|------------ 8 [R] COG2144 Selenophosphate synthetase-related proteins 4 5 5 10 ------------|-||----|---|--- 10 [S] COG2149 Predicted membrane protein 4 5 6 9 --|---------------|--||----| 10 [S] COG2155 Uncharacterized conserved protein 3 5 5 10 -------------|-------||-|--| 11 [G] COG2160 L-arabinose isomerase 3 5 10 20 --------------------|-|-||-| 25 [F] COG2169 Adenosine deaminase 3 5 6 10 --------------||----|---|--| 10 [M] COG2173 D-alanyl-D-alanine dipeptidase 3 5 6 14 -------------|---|---|||---- 14 [L] COG2176 DNA polymerase III, alpha subunit (gram-positive type) 4 5 6 11 -------------||||-----|----- 12 [R] COG2179 Predicted hydrolase of the HAD superfamily 1 5 5 5 |||---||-------------------- 10 [C] COG2218 Formylmethanofuran dehydrogenase subunit C 1 5 5 5 |||---||-------------------- 5 [R] COG2232 Predicted ATP-dependent carboligase related to biotin carboxylase 2 5 7 8 -|---||||------------------- 8 [R] COG2248 Predicted hydrolase (metallo-beta-lactamase superfamily) 4 5 5 9 -----|-------|||----|------- 9 [R] COG2251 Predicted nuclease (RecB family) 3 5 9 18 ------------------|---|-|-|| 37 [G] COG2271 Sugar phosphate permease 4 5 6 11 --------------||||----|----- 11 [S] COG2302 Uncharacterized conserved protein, contains S4-like domain 4 5 5 7 ---------------||----||-|--- 33 [T] COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 5 5 6 8 ---|------------|---|-|----| 9 [R] COG2312 Erythromycin esterase homolog 4 5 5 9 ---------------||-----|-|--| 18 [S] COG2318 Uncharacterized protein conserved in bacteria 3 5 5 5 |--|----------|||----------- 5 [S] COG2324 Predicted membrane protein 3 5 8 13 ----------------|---|---||-| 13 [S] COG2354 Uncharacterized protein conserved in bacteria 4 5 6 13 ----------------||--|||----- 21 [S] COG2357 Uncharacterized protein conserved in bacteria 4 5 5 7 ----------------|---|||-|--- 9 [S] COG2364 Predicted membrane protein 5 5 8 10 ------|-|-------|-----|-|--- 15 [Q] COG2368 Aromatic ring hydroxylase 4 5 7 8 -|--------------|-----|-||-- 11 [S] COG2369 Uncharacterized protein, homolog of phage Mu protein gp30 3 5 7 13 ----------------|---|---||-| 21 [P] COG2375 Siderophore-interacting protein 4 5 6 12 ----------------|---|||-|--- 17 [P] COG2382 Enterochelin esterase and related enzymes 3 5 6 13 ----------------|----||||--- 13 [R] COG2384 Predicted SAM-dependent methyltransferase 3 5 10 18 --|---|---------|-------|--| 19 [O] COG2386 ABC-type transport system involved in cytochrome c biogenesis, permease component 4 5 5 5 --|---------|-|||----------- 5 [R] COG2389 Uncharacterized metal-binding protein 3 5 5 6 -----||||---------------|--- 7 [R] COG2401 ABC-type ATPase fused to a predicted acetyltransferase domain 3 5 6 7 |----|-||------|------------ 8 [R] COG2403 Predicted GTPase 3 5 8 12 -||----||---------------|--- 15 [R] COG2425 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain 4 5 9 16 -----|--|--------|------||-- 16 [S] COG2431 Predicted membrane protein 1 5 5 6 -|||-||--------------------- 7 [S] COG2469 Uncharacterized conserved protein 4 5 6 12 -----------------|-|--|||--- 12 [E] COG2502 Asparagine synthetase A 3 5 6 8 --------------|-------|||-|- 8 [R] COG2503 Predicted secreted acid phosphatase 2 5 7 9 --|-|||-|------------------- 18 [S] COG2512 Uncharacterized membrane-associated protein/domain 5 5 7 14 --------|-------|---|-|----| 17 [R] COG2514 Predicted ring-cleavage extradiol dioxygenase 3 5 6 7 -|---|-||---------------|--- 7 [R] COG2521 Predicted archaeal methyltransferase 2 5 7 8 --||-||-|------------------- 13 [R] COG2522 Predicted transcriptional regulator 5 5 5 7 ----|----------|----||----|- 9 [R] COG2605 Predicted kinase related to galactokinase and mevalonate kinase 3 5 11 21 ----------------|---|---||-| 21 [C] COG2609 Pyruvate dehydrogenase complex, dehydrogenase (E1) component 3 5 7 15 ----------|----------||-||-- 16 [G] COG2706 3-carboxymuconate cyclase 3 5 5 6 ---------------|-----||-||-- 6 [R] COG2715 Uncharacterized membrane protein, required for spore maturation in B.subtilis. 3 5 7 13 ---|-----------------||-|--| 13 [S] COG2718 Uncharacterized conserved protein 3 5 7 13 ---|-----------------||-|--| 13 [S] COG2719 Uncharacterized conserved protein 4 5 5 6 ----------------|---|||-|--- 8 [V] COG2720 Uncharacterized vancomycin resistance protein 3 5 7 13 ---|-----------------||-|--| 14 [T] COG2766 Putative Ser protein kinase 3 5 5 5 |-|---|------|-------|------ 6 [R] COG2768 Uncharacterized Fe-S center protein 3 5 11 27 --------------------|-|-||-| 30 [L] COG2818 3-methyladenine DNA glycosylase 2 5 10 20 --------------||--------||-| 21 [M] COG2821 Membrane-bound lytic murein transglycosylase 3 5 10 17 ----------------|----|--||-| 28 [R] COG2823 Predicted periplasmic or secreted lipoprotein 4 5 6 8 --------------|-|-----|-||-- 9 [R] COG2842 Uncharacterized ATPase, putative transposase 2 5 7 12 ---------------------||-||-| 12 [D] COG2846 Regulator of cell morphogenesis and NO signaling 3 5 7 10 --------------------|-|-|||- 12 [C] COG2851 H+/citrate symporter 2 5 11 18 -----------------|------|||| 20 [M] COG2853 Surface lipoprotein 3 5 8 14 -------------------|--|-|-|| 14 [S] COG2861 Uncharacterized protein conserved in bacteria 2 5 9 12 ----------------|-------|||| 21 [C] COG2863 Cytochrome c553 2 5 12 21 ---------||-------------||-| 21 [I] COG2867 Oligoketide cyclase/lipid transport protein 3 5 6 14 -----------------|-|-|||---- 14 [J] COG2868 Predicted ribosomal protein 4 5 10 17 --|----------|---|------||-- 17 [C] COG2878 Predicted NADH:ubiquinone oxidoreductase, subunit RnfB 1 5 5 5 ||||--|--------------------- 12 [S] COG2881 Uncharacterized protein conserved in archaea 4 5 10 19 --------------|----|--|-||-- 19 [M] COG2891 Cell shape-determining protein 3 5 10 21 --------------------||--||-| 24 [P] COG2895 GTPases - Sulfate adenylate transferase subunit 1 4 5 5 9 ----------------|---|-|-|--| 9 [S] COG2899 Uncharacterized protein conserved in bacteria 3 5 9 15 ---------||---------|---|--| 15 [E] COG2902 NAD-specific glutamate dehydrogenase 5 5 6 6 ------|-----|-------|-|-|--- 8 [T] COG2905 Predicted signal-transduction protein containing cAMP-binding and CBS domains 3 5 9 13 ---------------|----|---||-| 13 [P] COG2906 Bacterioferritin-associated ferredoxin 2 5 11 21 -------------|----------|||| 23 [S] COG2908 Uncharacterized protein conserved in bacteria 2 5 7 11 ----------------------|-|||| 11 [R] COG2910 Putative NADH-flavin reductase 3 5 9 16 --------------|---|-----||-| 16 [S] COG2912 Uncharacterized conserved protein 2 5 8 10 --------------||--------||-| 13 [S] COG2929 Uncharacterized protein conserved in bacteria 3 5 5 5 ---------||--|----------||-- 7 [S] COG2930 Uncharacterized conserved protein 3 5 10 17 -----------------|----|-||-| 33 [K] COG2932 Predicted transcriptional regulator 4 5 7 10 ---------------|----|-|-|--| 16 [R] COG2936 Predicted acyl esterases 2 5 12 22 ---------||-------------||-| 22 [S] COG2938 Uncharacterized conserved protein 2 5 7 8 ---------||-------------||-| 8 [H] COG2941 Ubiquinone biosynthesis protein COQ7 2 5 7 13 --------------||--------||-| 16 [G] COG2942 N-acyl-D-glucosamine 2-epimerase 2 5 9 14 ---|--|-----------------||-| 14 [R] COG2945 Predicted hydrolase of the alpha/beta superfamily 2 5 5 8 --------------||--------||-| 10 [S] COG2954 Uncharacterized protein conserved in bacteria 3 5 7 10 ----------------|-----|-|-|| 10 [E] COG2957 Peptidylarginine deiminase and related enzymes 3 5 9 20 --------------------|-|-||-| 24 [R] COG2962 Predicted permeases 3 5 8 12 -----------------|---||-||-- 33 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain 3 5 5 5 |-------|---------------|||- 5 [H] COG2998 ABC-type tungstate transport system, permease component 4 5 7 11 --------------||----|-|-|--- 11 [G] COG3001 Fructosamine-3-kinase 3 5 7 7 --------|---|-----------|-|| 8 [R] COG3019 Predicted metal-binding protein 3 5 8 12 --------------|-------|-|-|| 14 [S] COG3041 Uncharacterized protein conserved in bacteria 3 5 6 6 |--|-----------|--------|--| 6 [R] COG3046 Uncharacterized protein related to deoxyribodipyrimidine photolyase 4 5 7 10 --|------------|------|-|--| 11 [M] COG3049 Penicillin V acylase and related amidases 2 5 12 19 ---------------------||-||-| 20 [K] COG3070 Regulator of competence-specific genes 4 5 9 13 -----------------|--|-|-|--| 43 [G] COG3090 TRAP-type C4-dicarboxylate transport system, small permease component 4 5 10 13 --------------|--|--|---|--| 21 [R] COG3093 Plasmid maintenance system antidote protein 3 5 8 14 ---------------||-------||-| 86 [NU] COG3121 P pilus assembly protein, chaperone PapD 3 5 7 13 -------------|-------||-||-- 14 [N] COG3144 Flagellar hook-length control protein 2 5 7 10 --------------||--------||-| 10 [S] COG3146 Uncharacterized protein conserved in bacteria 2 5 9 14 --------------||--------||-| 15 [NU] COG3166 Tfp pilus assembly protein PilN 2 5 7 11 ---------||-------------||-| 11 [O] COG3175 Cytochrome oxidase assembly factor 3 5 7 11 --------------|-----|---||-| 14 [R] COG3176 Putative hemolysin 3 5 8 10 --------------------|-|-||-| 19 [S] COG3182 Uncharacterized iron-regulated membrane protein 3 5 7 9 --------------|-------|-|-|| 12 [R] COG3211 Predicted phosphatase 4 5 6 7 --|-----------|------||-|--- 11 [E] COG3227 Zinc metalloprotease (elastase) 4 5 5 7 ----------------|---|-|-|--| 8 [J] COG3231 Aminoglycoside phosphotransferase 3 5 5 8 -|---|--------------|---||-- 8 [R] COG3233 Predicted deacetylase 4 5 8 17 --------------|-----|-|-|--| 26 [S] COG3237 Uncharacterized protein conserved in bacteria 4 5 7 13 --------|----|--------|-|--| 24 [G] COG3250 Beta-galactosidase/beta-glucuronidase 3 5 6 8 --------------------|-|-||-| 9 [S] COG3251 Uncharacterized protein conserved in bacteria 3 5 5 15 ----|-----------------|-|-|| 19 [S] COG3254 Uncharacterized conserved protein 3 5 7 10 --------|------|--------||-| 10 [P] COG3256 Nitric oxide reductase large subunit 2 5 5 5 ---------------|--------|||| 7 [C] COG3258 Cytochrome c 2 5 6 7 |-|---------------------|||- 18 [R] COG3271 Predicted double-glycine peptidase 3 5 6 7 -|-----|------|---------|--| 10 [S] COG3287 Uncharacterized conserved protein 4 5 5 5 --------------|||-----|-|--- 5 [S] COG3296 Uncharacterized protein conserved in bacteria 3 5 7 9 ---------------|------|-||-| 12 [T] COG3300 MHYT domain (predicted integral membrane sensor domain) 3 5 6 11 -----------------|---||-|--| 16 [S] COG3314 Uncharacterized protein conserved in bacteria 4 5 5 10 -----------------|--|||-|--- 11 [S] COG3323 Uncharacterized protein conserved in bacteria 4 5 5 6 --------|-----------|-|-|--| 7 [K] COG3327 Phenylacetic acid-responsive transcriptional repressor 4 5 5 6 --------------||----|-|----| 7 [R] COG3329 Predicted permease 3 5 5 5 -------------|||-----||----- 6 [S] COG3330 Uncharacterized protein conserved in bacteria 3 5 6 9 --------------|-------|-|-|| 9 [P] COG3338 Carbonic anhydrase 3 5 5 5 ---------||--|-------||----- 6 [R] COG3341 Predicted double-stranded RNA/RNA-DNA hybrid binding protein 4 5 5 8 ----|----------|------|-|--| 14 [S] COG3347 Uncharacterized conserved protein 2 5 6 6 ---|-||||------------------- 6 [K] COG3357 Predicted transcriptional regulator containing an HTH domain fused to a Zn-ribbon 2 5 5 6 |-||-----------------||----- 6 [L] COG3359 Predicted exonuclease 3 5 5 6 ---|----------------|---||-| 6 [S] COG3360 Uncharacterized conserved protein 1 5 5 5 |-||--||-------------------- 5 [R] COG3364 Zn-ribbon containing protein 1 5 5 5 |-||--||-------------------- 5 [S] COG3365 Uncharacterized protein conserved in archaea 1 5 5 5 -|||--||-------------------- 12 [S] COG3366 Uncharacterized protein conserved in archaea 3 5 5 5 ---|----------||--------||-- 5 [R] COG3380 Predicted NAD/FAD-dependent oxidoreductase 4 5 5 10 |---|---|-------------|----| 12 [R] COG3383 Uncharacterized anaerobic dehydrogenase 1 5 5 6 --|||-||-------------------- 6 [S] COG3388 Uncharacterized protein conserved in archaea 1 5 5 7 --|||||--------------------- 9 [S] COG3390 Uncharacterized protein conserved in archaea 4 5 6 11 ----------------||----|-|--| 12 [S] COG3412 Uncharacterized protein conserved in bacteria 3 5 8 15 --------------------|||||--- 38 [G] COG3414 Phosphotransferase system, galactitol-specific IIB component 2 5 7 8 -||-|-|-|------------------- 16 [K] COG3432 Predicted transcriptional regulator 4 5 6 8 --------|-----------|-|-||-- 10 [Q] COG3435 Gentisate 1,2-dioxygenase 4 5 5 7 ----|---------|-|-------||-- 8 [V] COG3440 Predicted restriction endonuclease 3 5 6 11 --------------||----|||----- 11 [R] COG3442 Predicted glutamine amidotransferase 2 5 6 11 ---------------------||-||-| 17 [L] COG3449 DNA gyrase inhibitor 3 5 6 9 -------------|-------||-|--| 9 [G] COG3459 Cellobiose phosphorylase 3 5 5 5 ----------------|-----|-||-| 5 [Q] COG3460 Uncharacterized enzyme of phenylacetate metabolism 3 5 6 6 -----------------|-|----|-|| 6 [P] COG3470 Uncharacterized protein probably involved in high-affinity Fe2+ transport 4 5 5 5 -|-|---------||-----|------- 6 [S] COG3472 Uncharacterized conserved protein 2 5 7 7 ----------|-------------|||| 11 [R] COG3491 Isopenicillin N synthase and related dioxygenases 3 5 6 7 --------|-----------|---||-| 15 [M] COG3511 Phospholipase C 4 5 6 7 --------------|-----|-|-|--| 10 [P] COG3540 Phosphodiesterase/alkaline phosphatase D 4 5 7 9 ---------|-----|------|--|-| 9 [S] COG3542 Uncharacterized conserved protein 3 5 5 7 |-|---|--------------|-----| 7 [S] COG3543 Uncharacterized conserved protein 4 5 5 6 --------------|||---|------| 10 [S] COG3544 Uncharacterized protein conserved in bacteria 3 5 6 11 ----------------|-----|-||-| 16 [R] COG3545 Predicted esterase of the alpha/beta hydrolase fold 4 5 6 9 --------|-----|------||-|--- 15 [P] COG3546 Mn-containing catalase 3 5 9 13 -----------------|--|---||-| 17 [R] COG3550 Uncharacterized protein related to capsule biosynthesis enzymes 4 5 5 7 |-------|-----------|----|-| 10 [R] COG3552 Protein containing von Willebrand factor type A (vWA) domain 3 5 5 7 ---------||-----|-------|--| 8 [L] COG3569 Topoisomerase IB 4 5 7 9 --------------|-|-----|-|--| 9 [S] COG3575 Uncharacterized protein conserved in bacteria 4 5 6 6 ------------||---|---||----- 7 [S] COG3580 Uncharacterized protein conserved in bacteria 4 5 6 6 ------------||---|---||----- 7 [S] COG3581 Uncharacterized protein conserved in bacteria 3 5 6 7 --|-----------|---------||-| 9 [H] COG3585 Molybdopterin-binding protein 4 5 5 10 --|-----------------|-|-|--| 10 [O] COG3590 Predicted metalloendopeptidase 3 5 6 8 --|------------------||-|--| 11 [G] COG3594 Fucose 4-O-acetylase and related acetyltransferases 2 5 6 8 --------------||--------|||- 12 [R] COG3596 Predicted GTPase 4 5 5 5 --------------|||-----|---|- 5 [S] COG3597 Uncharacterized protein/domain associated with GTPases 3 5 6 6 --------------------|-|||--| 8 [S] COG3600 Uncharacterized phage-associated protein 3 5 7 11 ------------|------|----||-| 21 [KT] COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains 2 5 6 9 |--|---|----------------|--| 15 [R] COG3608 Predicted deacylase 1 5 5 7 --|||||--------------------- 7 [K] COG3620 Predicted transcriptional regulator with C-terminal CBS domains 5 5 5 8 -------------|---|--|-|----| 14 [T] COG3629 DNA-binding transcriptional activator of the SARP family 1 5 5 5 |||---||-------------------- 17 [D] COG3640 CO dehydrogenase maturation factor 4 5 5 5 --------|----|--------|-|--| 7 [G] COG3669 Alpha-L-fucosidase 3 5 5 6 --------------||----|----|-| 12 [Q] COG3670 Lignostilbene-alpha,beta-dioxygenase and related enzymes 2 5 8 12 --------------||--------||-| 21 [UNTP] COG3678 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein 4 5 6 6 -------------||------||----| 9 [G] COG3693 Beta-1,4-xylanase 4 5 5 6 --------------||||----|----- 7 [R] COG3694 ABC-type uncharacterized transport system, permease component 5 5 8 14 ----------|-----|---|-|-|--- 14 [L] COG3695 Predicted methylated DNA-protein cysteine methyltransferase 3 5 6 11 -----------------|---||-|--| 22 [S] COG3708 Uncharacterized protein conserved in bacteria 4 5 6 15 -----------------|--|||-|--- 59 [K] COG3711 Transcriptional antiterminator 3 5 6 12 --------------------|-|-||-| 12 [G] COG3718 Uncharacterized enzyme involved in inositol metabolism 3 5 7 10 --------------------|-|-||-| 14 [R] COG3740 Phage head maturation protease 3 5 5 7 --------------||----|----|-| 15 [S] COG3744 Uncharacterized protein conserved in bacteria 3 5 6 12 -----------------|----|-||-| 12 [S] COG3758 Uncharacterized protein conserved in bacteria 3 5 7 11 --------------------|-|-||-| 12 [S] COG3759 Predicted membrane protein 3 5 6 11 |------|------------|||----- 22 [M] COG3764 Sortase (surface protein transpeptidase) 3 5 8 12 --------------|------|--||-| 43 [R] COG3772 Phage-related lysozyme (muraminidase) 2 5 5 8 --------------||--------||-| 8 [S] COG3781 Predicted membrane protein 3 5 6 8 --------------|||-------|--| 21 [P] COG3793 Tellurite resistance protein 3 5 5 8 --||----------||-----------| 21 [C] COG3794 Plastocyanin 5 5 6 9 --|-----|----|---|---------| 10 [C] COG3808 Inorganic pyrophosphatase 2 5 5 6 ----------------------|-|||| 6 [S] COG3817 Predicted membrane protein 2 5 5 6 ----------------------|-|||| 6 [S] COG3819 Predicted membrane protein 4 5 5 5 ----------------|---|-|-|--| 5 [O] COG3823 Glutamine cyclotransferase 3 5 6 11 ------------|--------||-||-- 20 [KT] COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains 4 5 5 8 --------------|-||------|--| 16 [S] COG3831 Uncharacterized conserved protein 3 5 7 14 ----------------|-----|-||-| 23 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 3 5 6 7 --------------|------|--||-| 8 [S] COG3837 Uncharacterized conserved protein, contains double-stranded beta-helix domain 2 5 5 7 ----------------------|-|||| 12 [U] COG3843 Type IV secretory pathway, VirD2 components (relaxase) 4 5 5 5 ------------|---|----|--||-- 7 [S] COG3868 Uncharacterized conserved protein 4 5 5 7 --------------|-|----||----| 8 [R] COG3871 Uncharacterized stress protein (general stress protein 26) 3 5 5 5 --|-----------||-----||----- 7 [S] COG3937 Uncharacterized conserved protein 3 5 6 12 --------------------|-|-||-| 13 [E] COG3962 Acetolactate synthase 3 5 6 7 --------------|------||--|-| 8 [M] COG3967 Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) 3 5 8 14 ----------------|---|---||-| 16 [Q] COG3971 2-keto-4-pentenoate hydratase 3 5 7 8 --------|-----||---------|-| 10 [R] COG3975 Predicted protease with the C-terminal PDZ domain 3 5 5 6 -|-------------------||---|| 6 [M] COG3980 Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase 2 5 5 5 |-|----|-||----------------- 5 [S] COG4021 Uncharacterized conserved protein 4 5 5 6 -|------------|-------||---| 7 [S] COG4095 Uncharacterized conserved protein 4 5 5 8 --|-----------|-------|-||-- 12 [V] COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases 3 5 7 8 --|-----------|---------||-| 15 [S] COG4104 Uncharacterized conserved protein 2 5 12 25 ------------|-----------|||| 25 [R] COG4105 DNA uptake lipoprotein 3 5 6 7 --------------||----|----|-| 23 [D] COG4118 Antitoxin of toxin-antitoxin stability system 4 5 5 6 --------------|-----||--|--| 6 [S] COG4185 Uncharacterized protein conserved in bacteria 4 5 5 5 ----|---|-----------|||----- 6 [R] COG4194 Predicted membrane protein 2 5 6 12 ----------------------||||-| 18 [G] COG4213 ABC-type xylose transport system, periplasmic component 2 5 6 12 ----------------------||||-| 17 [G] COG4214 ABC-type xylose transport system, permease component 3 5 7 8 --------------|-|-------||-| 9 [S] COG4226 Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters 2 5 10 17 ------------------|-----|||| 19 [OC] COG4232 Thiol:disulfide interchange protein 2 5 7 15 -------------------|----|||| 16 [R] COG4239 ABC-type uncharacterized transport system, permease component 3 5 5 6 ------------|-||--------|--| 10 [S] COG4244 Predicted membrane protein 3 5 5 5 --------------|||-------|--| 7 [T] COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase) 2 5 5 5 ---------||-------------||-| 5 [F] COG4266 Allantoicase 4 5 5 5 -------------|---|---|--||-- 5 [S] COG4267 Predicted membrane protein 4 5 5 6 --|-------------|-----|-|-|- 6 [V] COG4268 McrBC 5-methylcytosine restriction system component 3 5 5 5 --|--------------------|||-| 5 [K] COG4271 Predicted nucleotide-binding protein containing TIR -like domain 4 5 5 7 --|-----|-----||----|------- 8 [S] COG4279 Uncharacterized conserved protein 4 5 5 6 ---------|||------|--------| 7 [S] COG4286 Uncharacterized conserved protein related to MYG1 family 4 5 5 6 ----------|---||----|----|-- 6 [S] COG4301 Uncharacterized conserved protein 3 5 6 9 -----------------|---||-||-- 9 [E] COG4302 Ethanolamine ammonia-lyase, small subunit 3 5 6 9 -----------------|---||-||-- 9 [E] COG4303 Ethanolamine ammonia-lyase, large subunit 3 5 5 6 --------------|-------|-||-| 10 [S] COG4319 Ketosteroid isomerase homolog 4 5 5 5 ----------|---------|-|-|--| 5 [S] COG4336 Uncharacterized conserved protein 4 5 5 8 --------------||-|----|-|--- 10 [QC] COG4576 Carbon dioxide concentrating mechanism/carboxysome shell protein 4 5 5 8 --------------||-|----|-|--- 31 [QC] COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein 4 5 5 6 --------------||||----|----- 7 [R] COG4587 ABC-type uncharacterized transport system, permease component 4 5 5 5 ---------|||-|-------|------ 8 [R] COG4624 Iron only hydrogenase large subunit, C-terminal domain 4 5 5 5 ------------|-|||----------| 105 [S] COG4636 Uncharacterized protein conserved in cyanobacteria 5 5 5 5 --------------|-||---|----|- 7 [R] COG4639 Predicted kinase 3 5 5 7 ---------------|------|-||-| 7 [S] COG4642 Uncharacterized protein conserved in bacteria 5 5 8 14 --|----------|---|-|----|--- 14 [C] COG4658 Predicted NADH:ubiquinone oxidoreductase, subunit RnfD 3 5 5 5 |-------|---------------|||- 5 [H] COG4662 ABC-type tungstate transport system, periplasmic component 2 5 6 11 ---------------------||-||-| 21 [S] COG4695 Phage-related protein 4 5 5 6 ---|--|-----|-|------------| 6 [S] COG4711 Predicted membrane protein 5 5 5 5 --|-----------|----||-|----- 5 [S] COG4748 Uncharacterized conserved protein 3 5 7 14 ---|----------------|---||-| 24 [I] COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit 2 5 5 5 |-|---|-------||------------ 6 [C] COG4802 Ferredoxin-thioredoxin reductase, catalytic subunit 3 5 5 8 --|--------------|------||-| 13 [S] COG4804 Uncharacterized conserved protein 4 5 5 5 --|---|----------|---|--|--- 9 [O] COG4870 Cysteine protease 5 5 7 8 --|--------------|--|-|----| 9 [L] COG4912 Predicted DNA alkylation repair enzyme 4 5 6 6 --|-----------|--|------|--| 6 [S] COG4929 Uncharacterized membrane-anchored protein 4 5 5 5 --|------||---|---------|--- 8 [O] COG4935 Regulatory P domain of the subtilisin-like proprotein convertases and other proteases 3 5 6 9 --------------|||----||----- 9 [R] COG4956 Integral membrane protein (PIN domain superfamily) 3 5 8 9 --------------|||-------||-- 9 [NU] COG4972 Tfp pilus assembly protein, ATPase PilM 4 5 9 21 -----------------|--|-|-|--| 24 [CO] COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components 3 5 8 12 ----------------|---|---||-| 14 [R] COG5006 Predicted permease, DMT superfamily 3 5 12 23 ------------|------|----||-| 24 [M] COG5009 Membrane carboxypeptidase/penicillin-binding protein 3 5 5 6 |-|---|----------|---------| 21 [R] COG5012 Predicted cobalamin binding protein 2 5 7 11 ---------||-------------||-| 16 [O] COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components 3 5 5 6 --|--------------|------||-| 8 [P] COG5266 ABC-type Co2+ transport system, periplasmic component 2 5 5 6 -||--|-||------------------- 6 [J] COG5270 PUA domain (predicted RNA-binding domain) 4 5 6 7 --------------|-|-----|--|-| 12 [T] COG5278 Predicted periplasmic ligand-binding sensor domain 3 5 5 5 ---------||----|-----||----- 6 [D] COG5279 Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain 4 5 5 7 ---------|----|-----|----|-| 9 [Q] COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin 4 5 5 8 -----|--------||----|---|--- 13 [S] COG5305 Predicted membrane protein 4 5 6 7 ----|---|---------|-----|--| 8 [H] COG5424 Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C 4 5 6 6 ---------|---|-------|---|-| 11 [M] COG5434 Endopolygalacturonase 4 5 5 8 -------------||||---|------- 8 [R] COG5512 Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives 4 5 5 5 ---------|||--|------|------ 7 [S] COG5542 Predicted integral membrane protein 4 5 5 6 --|---|-------------|-|----| 9 [S] COG5658 Predicted integral membrane protein