y a o g aaaaaaaaaaaaaaaaaaaaaaaaaaaa 9 19 27 41 |||-||||||--|-|||-|---|-|||| 51 [H] COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases 12 19 27 53 -------|-||-|||||||||||||||| 73 [J] COG0050 GTPases - translation elongation factors 9 19 24 31 ||||-||||||||-|||-----|-||-| 55 [BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein 10 19 26 44 --|||-|--||-||||||--|||-|||| 46 [F] COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) 9 19 27 41 |||-||||||--|-|||-|---|-|||| 46 [H] COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase 9 19 26 39 -|||||-||||---||||--|||-||-| 73 [EH] COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes 11 19 27 52 |-||--------|||||||||||||||| 59 [L] COG0178 Excinuclease ATPase subunit 12 19 27 52 ---------||||||||||||||||||| 137 [I] COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase 13 19 27 49 ---|----|||||--||||||||||||| 62 [F] COG0208 Ribonucleotide reductase, beta subunit 12 19 27 52 ---------||||||||||||||||||| 52 [R] COG0220 Predicted S-adenosylmethionine-dependent methyltransferase 10 19 26 48 |-||----|||---||||-||||||||| 62 [O] COG0225 Peptide methionine sulfoxide reductase 12 19 27 51 --|------||-|||||||||||||||| 58 [O] COG0234 Co-chaperonin GroES (HSP10) 12 19 27 53 --|------||-|||||||||||||||| 115 [IQ] COG0236 Acyl carrier protein 9 19 26 43 -|||-|-|-||-|||||---|||-|||| 60 [D] COG0239 Integral membrane protein possibly involved in chromosome condensation 9 19 26 42 |||||-|||---|-||||--|-|-|||| 115 [C] COG0247 Fe-S oxidoreductase 12 19 27 44 --|||----|||||||||||-||-||-| 59 [L] COG0249 Mismatch repair ATPase (MutS family) 10 19 27 43 --|||-|-|||-|-||||--|||-|||| 171 [C] COG0277 FAD/FMN-containing dehydrogenases 9 19 29 47 --|||||-|||--||||---|||-|||| 69 [C] COG0281 Malic enzyme 11 19 26 44 --|||---|||-||||||--|||-|||| 45 [F] COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN 9 19 27 40 |||-|||||---|||||---|||-||-| 102 [R] COG0312 Predicted Zn-dependent proteases and their inactivated homologs 11 19 27 52 |-||--------|||||||||||||||| 63 [L] COG0322 Nuclease subunit of the excinuclease complex 11 19 28 48 |-|-|---|||-|||||--||||-|||| 56 [E] COG0345 Pyrroline-5-carboxylate reductase 9 19 27 45 |-||-||-|||---||||--|||-|||| 252 [E] COG0346 Lactoylglutathione lyase and related lyases 10 19 27 40 |-|||-|-|||||-|||---|-|-|||| 119 [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases 8 19 23 34 |||||||||-----||||--|||-||-| 35 [H] COG0368 Cobalamin-5-phosphate synthase 10 19 29 47 |-|||-|-|||-|||||---|-|-|||| 80 [C] COG0372 Citrate synthase 9 19 25 34 |||||||||---|||||---|-|-||-| 71 [R] COG0433 Predicted ATPase 10 19 25 41 ||-|-|-||||-|--||-|-|||-|||| 77 [P] COG0471 Di- and tricarboxylate transporters 12 19 26 42 --|-||--||||||-||--||||-|||| 77 [ER] COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases 10 19 26 38 ||||--||||--|||||-||----|||| 41 [R] COG0496 Predicted acid phosphatase 8 19 23 31 |||||||||||-||||----|---||-| 32 [H] COG0499 S-adenosylhomocysteine hydrolase 10 19 25 41 |||----|-||-||||-||-|||-|||| 49 [H] COG0502 Biotin synthase and related enzymes 11 19 25 41 ---||---|||||-|||-|-|||||||| 407 [RTKL] COG0515 Serine/threonine protein kinase 8 19 25 43 |||||||||---|-|-|---|||-|||| 54 [H] COG0521 Molybdopterin biosynthesis enzymes 9 19 26 46 |-||-||--|--|-|||--||||||||| 91 [R] COG0546 Predicted phosphatases 11 19 27 52 |-||--------|||||||||||||||| 53 [L] COG0556 Helicase subunit of the DNA excision repair complex 12 19 27 53 ---------||||||||||||||||||| 146 [J] COG0564 Pseudouridylate synthases, 23S RNA-specific 12 19 27 52 ------|--||-|||||||||||||||| 109 [J] COG0566 rRNA methylases 12 19 25 44 ---|||--||||-||-||-|||||||-| 93 [C] COG0584 Glycerophosphoryl diester phosphodiesterase 9 19 28 48 |||||||||-|-|-|||---|-|-||-| 207 [T] COG0589 Universal stress protein UspA and related nucleotide-binding proteins 7 19 28 47 |||||||||---|-||-|---||-|||| 61 [O] COG0602 Organic radical activating enzymes 9 19 26 46 -||||||-|----|||||--|||-|||| 181 [P] COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component 11 19 21 33 -|||-||||---||||||-||||||--- 48 [R] COG0618 Exopolyphosphatase-related proteins 9 19 22 38 ||||-||||----|||||--|||||--| 70 [P] COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters 7 19 27 43 |||||||||---||||-----||-|||| 55 [H] COG0720 6-pyruvoyl-tetrahydropterin synthase 11 19 28 48 --|-|-|-|---||||||-||||||||| 91 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins 8 19 26 43 |||||||||---|-|||---|-|-|||| 45 [H] COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A 11 19 27 50 |||----|----|||||||||||-|||| 50 [M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase 11 19 25 38 -----|||||||||--||--|||||||| 49 [K] COG0846 NAD-dependent protein deacetylases, SIR2 family 12 19 25 38 --||-||-||||-||-|||-|||-||-| 89 [R] COG1073 Hydrolases of the alpha/beta superfamily 8 19 26 38 |||-|||||----|||||---||-|||| 184 [C] COG1145 Ferredoxin 8 19 25 38 |||||||||----||||---||--|||| 84 [C] COG1146 Ferredoxin 9 19 24 37 |-|-|||||||||-||----|||-||-| 82 [M] COG1215 Glycosyltransferases, probably involved in cell wall biogenesis 12 19 24 37 |-||-|--|---|||||||||||-||-| 104 [R] COG1266 Predicted metal-dependent membrane protease 8 19 23 30 |||||||||-----||||--|||-||-| 31 [H] COG1270 Cobalamin biosynthesis protein CobD/CbiB 8 19 20 36 ||||||||----||--||-|-||||-|| 51 [R] COG1418 Predicted HD superfamily hydrolase 11 19 27 47 ----|-|-||||-|||-||-|||||||| 104 [I] COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes 12 19 27 43 --|-||||||--|||-|||-|-|-|||| 56 [R] COG1611 Predicted Rossmann fold nucleotide-binding protein 9 19 26 46 -|||||---||--||-||--|||||||| 183 [J] COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins 10 19 22 29 |||||||||--||||-|---|||-||-- 38 [S] COG1690 Uncharacterized conserved protein 8 19 24 31 |||||||||||||-------|-|-|||| 66 [L] COG1793 ATP-dependent DNA ligase 9 19 27 45 |||||||||----||-||--|||-||-| 336 [K] COG1846 Transcriptional regulators 11 19 27 44 |-|-|||-|-|-||||||--|||-||-| 100 [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family 9 19 22 34 ||||||--|---||||-|--|||-|||| 58 [S] COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain 8 19 26 40 ||||-|||----|||||---|||-|||| 50 [NOU] COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases 8 19 24 35 |||||||||-----||||--|||-||-| 36 [H] COG2038 NaMN:DMB phosphoribosyltransferase 11 19 23 36 |-||--|---|-|||||-|||||-|||| 446 [T] COG2202 FOG: PAS/PAC domain 9 19 26 42 |||||||||----||-||--|||-||-| 113 [R] COG2244 Membrane protein involved in the export of O-antigen and teichoic acid 11 19 28 46 -|||-|-||---|||||||-|||-||-| 49 [R] COG2262 GTPases