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 8 15 16 20 ||-|||-||||-|-||-|--|-|-----  34 [P]  COG0003 Oxyanion-translocating ATPase
 8 15 16 22 ||-|||||||--||-|----|||-----  25 [S]  COG0011 Uncharacterized conserved protein
10 15 23 41 ---||---|||-|||||---|-|-||-|  41 [F]  COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)
 7 15 18 26 ||||-|||||----||----|-|-|--|  46 [E]  COG0076 Glutamate decarboxylase and related PLP-dependent proteins
10 15 19 33 ---|||--|||-||||--|-|-|||---  61 [H]  COG0095 Lipoate-protein ligase A
 9 15 21 37 ---||-|-|||-|-|||---|-|-||-|  41 [O]  COG0109 Polyprenyltransferase (cytochrome oxidase assembly factor)
 8 15 18 23 -||-|-|||||-|-||----|-|---||  49 [EQ] COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit
 8 15 20 34 --||||--|||---|-|---|||-||-|  69 [E]  COG0160 4-aminobutyrate aminotransferase and related aminotransferases
10 15 23 45 --|------|||-|--|||-||||||-|  68 [H]  COG0262 Dihydrofolate reductase
 9 15 23 46 --||---------|-|||-|||||||||  70 [C]  COG0280 Phosphotransacetylase
 9 15 20 43 --|----------|||||-|||||||||  55 [C]  COG0282 Acetate kinase
 8 15 23 39 |--|----|||---|||---|||-||||  57 [P]  COG0288 Carbonic anhydrase
 6 15 21 36 |||||||||----|-----|-||||---  39 [H]  COG0301 Thiamine biosynthesis ATP pyrophosphatase
 9 15 23 41 --------|||-|-||||--|||-||||  44 [H]  COG0302 GTP cyclohydrolase I
 6 15 17 24 |||||||||---|-||-----|--|-|-  28 [O]  COG0309 Hydrogenase maturation factor
 9 15 23 44 ------------||||||-|||||||||  67 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases
 9 15 23 45 ------------|-||||||||||||||  45 [L]  COG0353 Recombinational DNA repair protein (RecF pathway)
 9 15 23 47 --|------|--||||-|--||||||||  47 [C]  COG0356 F0F1-type ATP synthase, subunit a
 9 15 23 47 ------------||||||-|||||||||  47 [M]  COG0357 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division
 8 15 21 39 --||----|||---||-|--||||||-|  76 [L]  COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair
 7 15 18 26 |||||||-|----|||----|-|-|--|  29 [S]  COG0393 Uncharacterized conserved protein
10 15 22 34 ----|---||||--||||--|-|-||||  48 [E]  COG0405 Gamma-glutamyltransferase
 9 15 22 41 --|-|----||-|-|||-|-|-|-||||  54 [H]  COG0407 Uroporphyrinogen-III decarboxylase
 7 15 18 22 ||||-||||||||-|---------||--  22 [A]  COG0430 RNA 3'-terminal phosphate cyclase
 7 15 17 21 ||||||||||--||||-----------|  70 [T]  COG0467 RecA-superfamily ATPases implicated in signal transduction
 9 15 20 37 -|-------||---|-|-||||||||||  52 [L]  COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member
 9 15 25 48 ---||---|||---|||-|-|-||||-| 122 [C]  COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes
 9 15 19 28 -----||-|||-|--||---|||-||||  33 [P]  COG0529 Adenylylsulfate kinase and related kinases
10 15 23 42 --|------||||-|||-|-|||-||-|  65 [FJ] COG0590 Cytosine/adenosine deaminases
 9 15 23 49 ------------|||||-||||||||||  73 [L]  COG0593 ATPase involved in DNA replication initiation
 9 15 23 48 -------------|||||||||||||||  48 [J]  COG0594 RNase P protein component
10 15 22 35 |------|----||||||-|||--||||  40 [O]  COG0606 Predicted ATPase with chaperone activity
 8 15 20 26 ||||--|-|---|||||----||-||--  34 [R]  COG0613 Predicted metal-dependent phosphoesterases (PHP family)
 7 15 18 22 |||||||||||||---------|----|  26 [MI] COG0615 Cytidylyltransferase
 9 15 23 48 -------------|||||||||||||||  48 [L]  COG0632 Holliday junction resolvasome, DNA-binding subunit
 7 15 19 31 --||-||------||||--|-||-||||  46 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases
 9 15 20 37 ---|||--||||-|-|----|||-||-|  96 [R]  COG0656 Aldo/keto reductases, related to diketogulonate reductase
 7 15 22 34 |-|||---|||---||----|||-||-|  52 [R]  COG0661 Predicted unusual protein kinase
 9 15 22 43 ------------||||||-|||||||||  43 [H]  COG0669 Phosphopantetheine adenylyltransferase
 8 15 22 39 ---------||---||||||-|||||||  51 [R]  COG0670 Integral membrane protein, interacts with FtsH
 9 15 19 26 -|-|--|-|----|||||--|-|-|||| 112 [E]  COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
 9 15 22 38 ---|--|-|----|||||-|-|||||-| 114 [E]  COG0687 Spermidine/putrescine-binding periplasmic protein
 8 15 23 47 ---------||-||||-|--||||||||  48 [C]  COG0712 F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)
 9 15 23 48 -------------|||||||||||||||  48 [S]  COG0718 Uncharacterized protein conserved in bacteria
10 15 23 46 ------------|||||||||||-||||  84 [OU] COG0740 Protease subunit of ATP-dependent Clp proteases
 9 15 23 46 -------------|||||||||||||||  46 [L]  COG0742 N6-adenine-specific methylase
10 15 21 37 ------------|||||||||||-||||  37 [I]  COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase
 9 15 23 42 ------------||||||-|||||||||  46 [LU] COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake
10 15 23 39 ------------|||||||||||-||||  39 [S]  COG0759 Uncharacterized conserved protein
10 15 21 38 ------------|||||||||||-||||  40 [IM] COG0761 Penicillin tolerance protein
10 15 23 46 ------------|||||||||||-||||  56 [M]  COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase
10 15 23 46 ------------|||||||||||-|||| 107 [M]  COG0768 Cell division protein FtsI/penicillin-binding protein 2
10 15 23 46 ------------|||||||||||-||||  92 [D]  COG0772 Bacterial cell division membrane protein
10 15 23 46 ------------|||||||||||-||||  60 [M]  COG0773 UDP-N-acetylmuramate-alanine ligase
 8 15 24 43 --|||-|-|---|-|||---|-|-||||  49 [U]  COG0805 Sec-independent protein secretion pathway component TatC
10 15 23 46 ------------|||||||||||-||||  48 [M]  COG0812 UDP-N-acetylmuramate dehydrogenase
 9 15 23 47 ------------|||||||-||||||||  47 [L]  COG0816 Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis)
 9 15 22 41 ------------||||||-|||||||||  46 [R]  COG0820 Predicted Fe-S-cluster redox enzyme
10 15 21 38 ------------|||||||||||-||||  38 [I]  COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis
 8 15 20 35 |||----||---|-|-||---||-||||  75 [O]  COG0826 Collagenase and related proteases
 7 15 19 31 --||-||------||||--|-||-|||| 323 [NT] COG0840 Methyl-accepting chemotaxis protein
 7 15 16 21 -||||---|-------|--|||||||||  39 [V]  COG1002 Type II restriction enzyme, methylase subunits
 7 15 22 33 -|||-||-|---|-||----|-|-||||  44 [M]  COG1004 Predicted UDP-glucose 6-dehydrogenase
 6 15 22 32 |||||||||-------||-|----|||-  44 [O]  COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2
 9 15 20 33 ----|||-|----|||-||-|-|-||||  44 [P]  COG1055 Na+/H+ antiporter NhaD and related arsenite permeases
10 15 23 42 ------------|||||||||||-||||  43 [O]  COG1066 Predicted ATP-dependent serine protease
 7 15 18 27 |||||||||--|||---|----||----  34 [R]  COG1078 HD superfamily phosphohydrolases
 7 15 16 26 |||-|--||-----||-|--|-|-||||  72 [R]  COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase
10 15 22 40 ------------|||||||||||-||||  44 [HI] COG1154 Deoxyxylulose-5-phosphate synthase
 9 15 23 48 ------------||||||-|||||||||  48 [R]  COG1159 GTPase
10 15 22 38 ----||--|||--||-||--|||-||-| 107 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
 9 15 22 38 ---|--|-|----||-||-|-|||||||  98 [E]  COG1177 ABC-type spermidine/putrescine transport system, permease component II
10 15 23 46 ------------|||||||||||-||||  47 [L]  COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase
 6 15 17 20 |||||||||||||-----------|--|  26 [R]  COG1204 Superfamily II helicase
 8 15 16 21 |||--||||||---|-|---|-|-|--|  27 [R]  COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
 9 15 15 22 --||-||-|||-|---|-|-|-|-||-|  22 [H]  COG1232 Protoporphyrinogen oxidase
 7 15 16 18 ||||||||||||-|---|---|------  18 [KB] COG1243 Histone acetyltransferase
 7 15 18 23 ||||||||||||-------|--|-|---  24 [I]  COG1257 Hydroxymethylglutaryl-CoA reductase
 8 15 22 32 |-|-|-|||----|-||---|-|-|||| 127 [E]  COG1280 Putative threonine efflux protein
 9 15 23 44 --|---------|-|||||-||||||||  63 [S]  COG1295 Predicted membrane protein
 9 15 23 47 ------------|-||||||||||||||  47 [U]  COG1314 Preprotein translocase subunit SecG
 9 15 23 46 ------------||||||-|||||||||  49 [S]  COG1385 Uncharacterized protein conserved in bacteria
11 15 23 40 |-|-----|---|||-||-||||-||-| 387 [K]  COG1396 Predicted transcriptional regulators
 9 15 23 49 ------------|||||-||||||||||  50 [L]  COG1466 DNA polymerase III, delta subunit
 9 15 17 25 ------------||||||-|||||||||  25 [K]  COG1521 Putative transcriptional regulator, homolog of Bvg accessory factor
 9 15 17 21 ----|||-||||-||-----|||-|-||  34 [R]  COG1524 Uncharacterized proteins of the AP superfamily
 7 15 15 18 ||||||||||||----||----|-----  18 [C]  COG1527 Archaeal/vacuolar-type H+-ATPase subunit C
 9 15 21 40 ---|--------||||||--||||||||  46 [R]  COG1546 Uncharacterized protein (competence- and mitomycin-induced)
 9 15 22 33 ||-|-|-||----|||||--||--|--|  35 [OU] COG1585 Membrane protein implicated in regulation of membrane protease activity
 7 15 16 26 -|||-|||----|-|||-||-|||----  27 [S]  COG1624 Uncharacterized conserved protein
 9 15 22 38 ---|||--|----||||--||||-||-| 209 [G]  COG1653 ABC-type sugar transport system, periplasmic component
 5 15 19 31 |||||||||---|---------|-||||  33 [H]  COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein
 6 15 17 19 |||-|-|||-----||-|---||-||-|  19 [H]  COG1903 Cobalamin biosynthesis protein CbiD
 6 15 19 25 |||--|||-----|-||----||-||||  29 [P]  COG1918 Fe2+ transport system protein A
 9 15 21 28 --|||---|----||-||--|||-|||| 153 [L]  COG1943 Transposase and inactivated derivatives
 7 15 17 19 |-|||||||----|-||----||-|--|  29 [S]  COG2013 Uncharacterized conserved protein
 9 15 21 33 ---||-|-|||--|--||--|||-||-|  57 [C]  COG2025 Electron transfer flavoprotein, alpha subunit
 8 15 21 40 --|||||-|-|-|---|---|-|-||||  88 [Q]  COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism
 6 15 17 21 ||-||-|||-----||-|---||-||-|  25 [H]  COG2073 Cobalamin biosynthesis protein CbiG
 8 15 23 36 |-|-|---|---|-|||---|||-||||  79 [I]  COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
 9 15 21 33 ---||-|-|||--|--||--|||-||-|  54 [C]  COG2086 Electron transfer flavoprotein, beta subunit
 8 15 16 23 --|-||||-||--|--||-|-||||---  25 [F]  COG2131 Deoxycytidylate deaminase
 7 15 19 33 ||||--|||-----|-|---|-||||-| 165 [C]  COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
 9 15 19 30 ---|-----|||-||||--|-|-||||| 100 [O]  COG2214 DnaJ-class molecular chaperone
 7 15 18 24 |-||-|||-||-|-|-----|||-|--|  41 [R]  COG2234 Predicted aminopeptidases
 9 15 23 48 -------------|||||||||||||||  49 [L]  COG2255 Holliday junction resolvasome, helicase subunit
 8 15 21 37 --|-|-|--||---||||--|-||||-| 415 [L]  COG2801 Transposase and inactivated derivatives
10 15 16 25 --||----|-|-|-||||--|||-||-|  33 [R]  COG4122 Predicted O-methyltransferase