y a o g aaaaaaaaaaaaaaaaaaaaaaaaaaaa 5 14 19 26 |||||||||||---||--------|--- 29 [J] COG0023 Translation initiation factor 1 (eIF-1/SUI1) and related proteins 9 14 23 42 --||----|||----||-|-|-|-|||| 43 [C] COG0114 Fumarase 9 14 20 36 -|-------|--|-||-||-|||-|||| 46 [H] COG0132 Dethiobiotin synthetase 9 14 20 32 ------|-|||-|-|||---|||-||-| 45 [P] COG0155 Sulfite reductase, beta subunit (hemoprotein) 9 14 20 37 -|-------||-|---|||-|||-|||| 78 [H] COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase 6 14 22 34 -|||-||-|-----|||-----||||-| 55 [HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) 9 14 22 43 ----|----||-|-|||-|-|-|-|||| 44 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) 5 14 22 36 ||||-||-------|-----|-|||||| 68 [V] COG0286 Type I restriction-modification system methyltransferase subunit 5 14 21 34 |||||-||-|||-------|----||-| 41 [J] COG0293 23S rRNA methylase 11 14 18 28 --|-----||--|-|||||-|-|-||-| 39 [G] COG0296 1,4-alpha-glucan branching enzyme 9 14 17 27 --|--|--||||--|--|--|||-||-| 40 [R] COG0300 Short-chain dehydrogenases of various substrate specificities 9 14 21 36 --|-|---||||--|||---|-|-||-| 51 [E] COG0308 Aminopeptidase N 10 14 23 40 ---|----|||-|-|||-|-|-|-||-| 43 [H] COG0320 Lipoate synthase 8 14 19 35 ---------|||--||-|-||||-|||| 37 [O] COG0326 Molecular chaperone, HSP90 family 9 14 21 39 ---|----|||---|||--||-|-|||| 44 [L] COG0328 Ribonuclease HI 6 14 19 29 ||-|-|-------||||----||-|||| 36 [M] COG0381 UDP-N-acetylglucosamine 2-epimerase 8 14 18 28 --||-----||---||||--|||-||-| 43 [R] COG0384 Predicted epimerase, PhzC/PhzF homolog 9 14 18 25 -|----|-|----|||||--|-|-|||| 72 [E] COG0410 ABC-type branched-chain amino acid transport systems, ATPase component 8 14 19 36 ---------||-|||||---|||-|||| 37 [H] COG0414 Panthothenate synthetase 8 14 20 39 ------------|||||||--||||||| 39 [I] COG0416 Fatty acid/phospholipid biosynthesis enzyme 6 14 18 24 ||||||||||||--|---------|--- 47 [L] COG0417 DNA polymerase elongation subunit (family B) 9 14 19 32 --|------||-|-||||--|-|-|||| 67 [R] COG0523 Putative GTPases (G3E family) 9 14 18 25 -|----|-|----|||||--|-|-|||| 73 [E] COG0559 Branched-chain amino acid ABC-type transport system, permease components 5 14 22 32 |||||-|||-----|||-------||-| 36 [J] COG0565 rRNA methylase 10 14 19 36 ---||---||||---||--||-|-||-| 53 [C] COG0578 Glycerol-3-phosphate dehydrogenase 9 14 21 35 --|||---|||-|-|-|---|-|-||-| 139 [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases 9 14 19 35 ---|-||-|||-||---|--|-|-|-|| 46 [G] COG0647 Predicted sugar phosphatases of the HAD superfamily 9 14 18 30 --|------||||-||--|-|-|-|||| 60 [P] COG0659 Sulfate permease and related transporters (MFS superfamily) 9 14 17 24 ------|-|||--|||-|-|--|-|||| 26 [P] COG0672 High-affinity Fe2+/Pb2+ permease 9 14 20 42 ---------|||----|||||-|||||| 43 [L] COG0692 Uracil DNA glycosylase 7 14 15 21 |||---||----||||----|||-|-|- 26 [R] COG0701 Predicted permeases 8 14 22 46 --|---------||||-|--|||||||| 62 [C] COG0711 F0F1-type ATP synthase, subunit b 6 14 18 27 -|||-||-|-----|||-----|-|||| 43 [R] COG0727 Predicted Fe-S-cluster oxidoreductase 10 14 21 39 ------------||||||||||--|||| 41 [R] COG0728 Uncharacterized membrane protein, putative virulence factor 5 14 21 35 |||||||-------|-----|-|||-|| 88 [V] COG0732 Restriction endonuclease S subunits 8 14 16 25 -|||-||-----|----||||-|-|||- 43 [R] COG0733 Na+-dependent transporters of the SNF family 9 14 22 42 ------------||||||-||||-|||| 147 [M] COG0739 Membrane proteins related to metalloendopeptidases 9 14 22 43 ------------|||||||-|||-|||| 429 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain 9 14 21 40 ---------||||----||||||-|||| 46 [F] COG0756 dUTPase 9 14 20 42 --|----------|--|||||||||||| 64 [F] COG0775 Nucleoside phosphorylase 9 14 22 42 ------------||||||-||||-|||| 42 [S] COG0779 Uncharacterized protein conserved in bacteria 9 14 22 43 ----------|-|-||||-||||-|||| 58 [M] COG0787 Alanine racemase 8 14 22 42 --|---|-----|-||||--|||-|||| 178 [K] COG0789 Predicted transcriptional regulators 7 14 14 17 |-|--||--|---|||----|||-||-| 22 [P] COG0798 Arsenite efflux pump ACR3 and related permeases 9 14 22 44 ------------||||||-||||-|||| 44 [J] COG0806 RimM protein, required for 16S rRNA processing 6 14 18 30 --||-||------|||---|-||-|||| 76 [NT] COG0835 Chemotaxis signal transduction protein 7 14 21 35 --|||-|-|---|-|||---|---|||| 38 [C] COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A) 7 14 20 34 --|||-|-|---|-|||---|---|||| 40 [C] COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J) 9 14 21 35 --|---------||||||-|-||-|||| 149 [V] COG0841 Cation/multidrug efflux pump 9 14 22 39 ------------||||||-||||-|||| 288 [M] COG0845 Membrane-fusion protein 9 14 20 40 ------------|-|||||||||-|||| 85 [M] COG0860 N-acetylmuramoyl-L-alanine amidase 7 14 21 35 --|||-|-|---|-|||---|---|||| 38 [C] COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H) 7 14 21 35 --|||-|-|---|-|||---|---|||| 37 [C] COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N) 9 14 22 40 ------------||||||-||||-|||| 43 [R] COG1040 Predicted amidophosphoribosyltransferases 8 14 23 38 --|||---|||-|---|---|||-||-| 48 [C] COG1048 Aconitase A 7 14 17 25 |||||||-|------||---|-|-||-- 29 [H] COG1056 Nicotinamide mononucleotide adenylyltransferase 9 14 17 32 ------|-|||--|||---||||-||-| 90 [G] COG1070 Sugar (pentulose and hexulose) kinases 8 14 16 27 ---|-||-|----||-|--|-|||||-| 42 [R] COG1079 Uncharacterized ABC-type transport system, permease component 9 14 20 37 --|---------||||-|-|||||||-| 40 [R] COG1162 Predicted GTPases 9 14 21 37 ---|--|-|----||-||-|-|||||-| 88 [E] COG1176 ABC-type spermidine/putrescine transport system, permease component I 9 14 20 30 ---|-|--|-----||||-||-|-|||| 65 [P] COG1178 ABC-type Fe3+ transport system, permease component 9 14 17 31 --|---|-----||||-|-|||||--|| 31 [J] COG1189 Predicted rRNA methylase 9 14 15 23 |-||-|------||||||-|-||---|- 26 [L] COG1193 Mismatch repair ATPase (MutS family) 9 14 22 43 |--|----|-|-----|-|||||-|||| 44 [L] COG1194 A/G-specific DNA glycosylase 9 14 22 45 -------------||||||||||-|||| 45 [LK] COG1197 Transcription-repair coupling factor (superfamily II helicase) 9 14 22 43 ------------||||||-||||-|||| 43 [LK] COG1200 RecG-like helicase 5 14 18 27 |||||||||-----|-----|---||-| 38 [R] COG1201 Lhr-like helicases 7 14 18 25 |-|-|||-|-----|||---||--||-| 54 [R] COG1216 Predicted glycosyltransferases 7 14 20 36 --|||-|-----|-||--|-|-|-|||| 52 [C] COG1271 Cytochrome bd-type quinol oxidase, subunit 1 9 14 21 33 ---||---||--|-|||---|-|-|||| 45 [C] COG1290 Cytochrome b subunit of the bc complex 6 14 15 19 |||--||||-----||----|||-|--| 23 [S] COG1300 Uncharacterized membrane protein 9 14 16 20 |-|||-|-|---|-|-|-|-|||----| 24 [O] COG1331 Highly conserved protein containing a thioredoxin domain 10 14 16 26 ---|||--|---||||--||||----|| 26 [F] COG1351 Predicted alternative thymidylate synthase 7 14 16 23 |||--||-|----|--|-|--||-||-| 28 [P] COG1392 Phosphate transport regulator (distant homolog of PhoU) 9 14 15 24 |-|-----|---|-|-|-|-|||-|||| 30 [R] COG1408 Predicted phosphohydrolases 7 14 16 21 -|||-|-------||--|--|||||||- 58 [S] COG1479 Uncharacterized conserved protein 9 14 21 37 ------------|-|||||||||-|||| 39 [S] COG1496 Uncharacterized conserved protein 9 14 17 23 ---||||||-|-|||-|----||-|--- 23 [L] COG1515 Deoxyinosine 3'endonuclease (endonuclease V) 7 14 18 26 ||||-||------|--|--||-|-||-| 66 [S] COG1520 FOG: WD40-like repeat 10 14 18 30 --|-----|----|-||||-||||||-| 36 [G] COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases 8 14 21 41 ---------||---|||||-|||-|||| 47 [H] COG1539 Dihydroneopterin aldolase 10 14 21 38 ------------|||||||||||-||-| 43 [J] COG1544 Ribosome-associated protein Y (PSrp-1) 9 14 16 24 --||||--|---||--||--|-|-||-| 33 [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold 9 14 21 39 ---|--|-|---|-|||-|-|-|-|||| 65 [O] COG1651 Protein-disulfide isomerase 6 14 17 19 ||||||||||||----|-------|--- 20 [TD] COG1718 Serine/threonine protein kinase involved in cell cycle control 10 14 18 29 --||--|-|----|--|||||-|-||-| 32 [S] COG1738 Uncharacterized conserved protein 8 14 16 28 ---|-||-|----||-|--|-|||||-| 54 [R] COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein 8 14 17 22 ||---||------|||-|-|||--||-| 33 [C] COG1773 Rubredoxin 6 14 18 25 |||--||||---||-------||-||-| 38 [C] COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain 8 14 19 30 ---|-||-|||-|-|-----|||-||-| 44 [H] COG1893 Ketopantoate reductase 6 14 16 18 ||||||||||||--|------------| 20 [O] COG1899 Deoxyhypusine synthase 6 14 18 25 |||--||||---||-------||-||-| 37 [C] COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain 9 14 20 34 ---||-|-||----|-||--|||-||-| 309 [I] COG1960 Acyl-CoA dehydrogenases 8 14 21 38 ---||-|-|||-----|-|-|-|-|||| 40 [C] COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit 9 14 19 32 ----|---|||--|||||---||-||-| 58 [G] COG2017 Galactose mutarotase and related enzymes 8 14 15 20 --|--||-||||--||----||--||-| 39 [O] COG2020 Putative protein-S-isoprenylcysteine methyltransferase 8 14 19 29 --|||-|-|---|-|-|---|-|-|||| 43 [R] COG2041 Sulfite oxidase and related enzymes 5 14 19 24 |||||||||-----------||--||-| 44 [NU] COG2064 Flp pilus assembly protein TadC 10 14 18 30 ------|--|--|||-||--|||-|||| 53 [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase 6 14 16 18 |||||||||||-||-------|------ 19 [S] COG2078 Uncharacterized conserved protein 8 14 16 26 --||||--|----|||||--|---||-| 30 [H] COG2109 ATP:corrinoid adenosyltransferase 7 14 19 32 |||-||-||----|--|---|-|-||-| 43 [R] COG2151 Predicted metal-sulfur cluster biosynthetic enzyme 9 14 19 31 |------------|||-|||||||||-| 43 [P] COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain) 6 14 19 28 ---||||||-----||----|||-||-| 37 [S] COG2246 Predicted membrane protein 9 14 19 33 -----||--||--||-||--|||-||-| 54 [I] COG2267 Lysophospholipase 6 14 17 21 |-|||-|||||---------|-|-||-| 37 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog 5 14 21 32 ||||-||||-|--|----------|||| 46 [O] COG2518 Protein-L-isoaspartate carboxylmethyltransferase 8 14 16 27 ---|-||-|----||-|--|-|||||-| 41 [R] COG3845 ABC-type uncharacterized transport systems, ATPase components 9 14 18 25 -|----|-|----|||||--|-|-|||| 72 [E] COG4177 ABC-type branched-chain amino acid transport system, permease component 8 14 16 27 ---|-||-|----||-|--|-|||||-| 43 [R] COG4603 ABC-type uncharacterized transport system, permease component 9 14 21 36 ---------||-||||||||----|||| 38 [M] COG4775 Outer membrane protein/protective antigen OMA87 9 14 16 25 ---|-||-|||--|--||--|-|-||-| 52 [I] COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)