y a o g aaaaaaaaaaaaaaaaaaaaaaaaaaaa 6 10 17 31 --------|||---|||---|---||-| 31 [H] COG0321 Lipoate-protein ligase B 6 10 17 31 ---------||-|-|||---|---||-| 31 [R] COG0354 Predicted aminomethyltransferase related to GcvT 6 10 14 24 ---------|||--||--|---|-||-| 34 [P] COG0369 Sulfite reductase, alpha subunit (flavoprotein) 6 10 13 20 --||--|--|-----|----|-|-||-| 21 [P] COG0376 Catalase (peroxidase I) 7 10 13 24 --|------|--|-||----|-|-||-| 36 [R] COG0385 Predicted Na+-dependent transporter 7 10 10 15 -||---------||||----|-|-||-- 15 [R] COG0390 ABC-type uncharacterized transport system, permease component 4 10 11 14 -|-|-||||-----||--------|--| 14 [R] COG0434 Predicted TIM-barrel enzyme 4 10 15 21 --||-||-|---|-----------|||| 73 [C] COG0437 Fe-S-cluster-containing hydrogenase components 1 4 10 12 13 -|||-|||||||---------------- 14 [T] COG0478 RIO-like serine/threonine protein kinase fused to N-terminal HTH domain 3 10 14 21 -||||||-|---------------|-|| 52 [NU] COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis 5 10 10 15 |||-||-||----|------|---|--- 23 [C] COG0650 Formate hydrogenlyase subunit 4 6 10 17 30 ---------||---|||---|-|-||-| 109 [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases 5 10 14 21 ||---|--|----|-------||-||-| 24 [M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase 6 10 19 33 --------|---||||------|-|||| 34 [R] COG0780 Enzyme related to GTP cyclohydrolase I 5 10 17 30 -------------|||---|-||-|||| 40 [G] COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase 5 10 16 32 -------------||||----||-|||| 35 [M] COG0818 Diacylglycerol kinase 6 10 17 30 ------------|-|||||-----|||| 65 [U] COG0848 Biopolymer transport protein 5 10 17 35 --------------|||---|||-|||| 74 [P] COG0861 Membrane protein TerC, possibly involved in tellurium resistance 6 10 13 19 ---------||-|---|---|-|-|||| 19 [C] COG1017 Hemoglobin-like flavoprotein 7 10 15 28 ---|-----||-----||--|-|-||-| 78 [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 6 10 13 24 ----|--------||-----|||-|||| 25 [E] COG1027 Aspartate ammonia-lyase 5 10 11 16 --|-|||-|---|---------|-||-| 18 [O] COG1030 Membrane-bound serine protease (ClpP class) 6 10 14 25 --------|||---||----|-|-||-| 42 [C] COG1062 Zn-dependent alcohol dehydrogenases, class III 6 10 18 39 -----------------||||||-|||| 39 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) 4 10 12 14 |-|-||||||||---------------- 17 [J] COG1097 RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain) 3 10 12 15 |||||||||----------|-------- 15 [F] COG1102 Cytidylate kinase 7 10 14 27 -------------|--||-|||||||-- 38 [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) 2 10 10 12 ||||||||-||----------------- 13 [L] COG1111 ERCC4-like helicases 7 10 12 25 ------|-------|-||--|||-|-|| 31 [E] COG1125 ABC-type proline/glycine betaine transport systems, ATPase components 4 10 10 15 |||--|||-----|||--------|--- 45 [C] COG1142 Fe-S-cluster-containing hydrogenase components 2 5 10 10 14 |||--|||-----|---|---|--|--- 19 [C] COG1151 6Fe-6S prismane cluster-containing protein 6 10 13 27 ------------||----||-||-|||| 41 [NU] COG1157 Flagellar biosynthesis/type III secretory pathway ATPase 4 10 11 13 -||||||-|||--|-------------- 20 [J] COG1184 Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family 6 10 16 30 ---------||-|-||--|-|---|-|| 31 [P] COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase 3 10 12 14 |||||||||--|---------------- 14 [J] COG1258 Predicted pseudouridylate synthase 7 10 12 16 --||--|-|---||||--|-|------- 16 [S] COG1259 Uncharacterized conserved protein 7 10 12 16 |-|--||-||--||------|------| 19 [I] COG1260 Myo-inositol-1-phosphate synthase 7 10 15 22 --|-------|---||--|-|-|-||-| 39 [S] COG1262 Uncharacterized conserved protein 5 10 13 22 -|--|||--||---------|-|-||-- 29 [P] COG1275 Tellurite resistance protein and related permeases 7 10 11 22 -------|-----|---|||-||||--| 50 [S] COG1284 Uncharacterized conserved protein 6 10 15 29 --|---|---------||--|-|-|||| 35 [E] COG1296 Predicted branched-chain amino acid permease (azaleucine resistance) 6 10 13 27 ------------||----||-||-|||| 31 [NU] COG1298 Flagellar biosynthesis pathway, component FlhA 5 10 11 12 |||--||||---||-------|------ 13 [R] COG1313 Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins 5 10 11 12 |||-||-||----||-----|------- 17 [L] COG1337 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) 6 10 13 27 ------------||----||-||-|||| 29 [NU] COG1338 Flagellar biosynthesis pathway, component FliP 7 10 15 29 ------------||--||--|||-||-| 145 [KG] COG1349 Transcriptional regulators of sugar metabolism 3 10 11 12 ||||-||||||----------------- 12 [J] COG1369 RNase P/RNase MRP subunit POP5 6 10 13 27 ------------||----||-||-|||| 32 [NU] COG1377 Flagellar biosynthesis pathway, component FlhB 6 10 10 13 -||---|-----|-|-|----||-|--| 15 [O] COG1397 ADP-ribosylglycohydrolase 7 10 16 30 ------------|||||---|||-||-- 30 [R] COG1399 Predicted metal-binding, possibly nucleic acid-binding protein 7 10 12 15 |-|--|--|---|--||-----|-|-|- 16 [V] COG1401 GTPase subunit of restriction endonuclease 6 10 14 24 ---|----------|||---|||-||-| 58 [V] COG1403 Restriction endonuclease 3 10 13 18 |||||||||------------------| 22 [R] COG1407 Predicted ICC-like phosphoesterases 6 10 15 25 -------------||||---|||-||-| 28 [E] COG1410 Methionine synthase I, cobalamin-binding domain 7 10 14 25 ---|--------||--|---|-|-|||| 99 [K] COG1414 Transcriptional regulator 5 10 13 18 ---|||--|-|---||--------||-| 21 [E] COG1446 Asparaginase 4 10 12 14 |-|||||-||||---------------- 41 [LO] COG1474 Cdc6-related protein, AAA superfamily ATPase 7 10 13 22 --|-----------||||--|||-|--| 26 [G] COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins 8 10 14 22 -||---------||--||-|--|-|--| 25 [E] COG1509 Lysine 2,3-aminomutase 6 10 13 27 ------------||----||-||-|||| 30 [N] COG1536 Flagellar motor switch protein 7 10 12 13 |-|---|-|-----|-||----|-||-- 23 [H] COG1541 Coenzyme F390 synthetase 7 10 11 19 ---------||--|--||-|-||---|| 19 [H] COG1564 Thiamine pyrophosphokinase 5 10 17 34 -------------|--||---||||||| 34 [S] COG1576 Uncharacterized conserved protein 6 10 18 37 --------------|||--||||-||-| 37 [M] COG1589 Cell division septal protein 3 10 11 12 ||||-||||||----------------- 12 [J] COG1603 RNase P/RNase MRP subunit p30 6 10 16 31 -------------|--||--||||||-| 277 [K] COG1609 Transcriptional regulators 4 10 12 14 |||-|||||---||-------------- 14 [F] COG1618 Predicted nucleotide kinase 3 10 12 14 |||||||||-------|----------- 14 [S] COG1628 Uncharacterized conserved protein 5 10 10 10 |||---||-----|||----||------ 12 [S] COG1641 Uncharacterized conserved protein 3 10 12 17 |||||||||-------------|----- 18 [R] COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold 7 10 12 15 ----|||||---||-----||----|-- 16 [S] COG1656 Uncharacterized conserved protein 6 10 12 16 |-|---------||---|---||-||-| 17 [S] COG1683 Uncharacterized conserved protein 5 10 10 10 |||---||-----|||----||------ 10 [R] COG1691 NCAIR mutase (PurE)-related proteins 6 10 14 21 -||----------|---|-|--||||-| 22 [S] COG1704 Uncharacterized conserved protein 6 10 14 24 --|-|---|-----||----||--||-| 45 [R] COG1741 Pirin-related protein 6 10 12 20 ---|-|--|--------|-|-||-|||- 43 [C] COG1757 Na+/H+ antiporter 6 10 16 34 -----------------|||||||||-| 127 [GT] COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) 5 10 14 18 |||--||||--------|----|-|--- 22 [H] COG1767 Triphosphoribosyl-dephospho-CoA synthetase 8 10 11 14 ---------|||||--||-|-||----- 16 [S] COG1774 Uncharacterized homolog of PSP1 5 10 10 15 --||-||------|-----|-||-|-|- 25 [NT] COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation 3 10 12 14 |||-|||||||----------------- 14 [R] COG1779 C4-type Zn-finger protein 6 10 13 19 ---------||---|----||||-||-| 24 [F] COG1816 Adenosine deaminase 3 10 11 12 |||||||||----|-------------- 12 [S] COG1833 Uncharacterized conserved protein 7 10 13 21 --|---------|-|||---|||-|--| 30 [KT] COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription 6 10 11 13 --|------||---|--|-|----|||| 15 [F] COG1864 DNA/RNA endonuclease G, NUC1 2 10 10 13 ||||||||-------------||----- 25 [S] COG1873 Uncharacterized conserved protein 6 10 10 17 |---|---||||--------|---||-| 24 [G] COG1877 Trehalose-6-phosphatase 7 10 15 25 --|----------|---|-||||-||-| 183 [G] COG1879 ABC-type sugar transport system, periplasmic component 6 10 13 27 ------------||----||-||-|||| 45 [NU] COG1886 Flagellar motor switch/type III secretory pathway protein 4 10 12 13 |||--|||||||---------------- 14 [J] COG1911 Ribosomal protein L30E 6 10 17 32 --|------||---|-----|-|-|||| 32 [HE] COG1932 Phosphoserine aminotransferase 5 10 12 22 --------------|||---|||-|||| 38 [S] COG1937 Uncharacterized protein conserved in bacteria 6 10 16 30 -------------||||---|||-||-| 50 [KT] COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases) 7 10 15 26 -----|---|------||--|-|-|||| 31 [E] COG1984 Allophanate hydrolase subunit 2 4 10 12 20 |||--||||------------||-|--- 35 [R] COG1988 Predicted membrane-bound metal-dependent hydrolases 3 10 10 11 ||||-|||-|||---------------- 40 [B] COG2036 Histones H3 and H4 4 10 10 11 |||||--|||||---------------- 11 [S] COG2042 Uncharacterized conserved protein 5 10 10 10 |||---|||---|-||----------|- 17 [C] COG2048 Heterodisulfide reductase, subunit B 7 10 15 25 -----|---|------||--|-|-|||| 30 [E] COG2049 Allophanate hydrolase subunit 1 6 10 15 22 --------|-------||--|||-|||| 32 [I] COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit 6 10 17 28 ------|-|---|-||----|---|||| 31 [T] COG2062 Phosphohistidine phosphatase SixA 6 10 12 21 --------------||||--|||-||-| 22 [H] COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase 8 10 11 18 --------|--|----|-|||||-|--| 19 [L] COG2094 3-methyladenine DNA glycosylase 6 10 13 18 -||--|--|-----|||-----|-||-- 18 [S] COG2105 Uncharacterized conserved protein 7 10 11 16 --|------|||--||---||---|--| 102 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) 4 10 12 14 |-|-||||||||---------------- 17 [J] COG2123 RNase PH-related exoribonuclease 6 10 14 27 --|---|-------|-|---|||-||-| 59 [S] COG2128 Uncharacterized conserved protein 7 10 13 20 --------|-----|||--||-|-||-| 30 [G] COG2133 Glucose/sorbosone dehydrogenases 4 10 12 13 |||--|||||||---------------- 16 [JA] COG2136 Predicted exosome subunit/U3 small nucleolar ribonucleoprotein (snoRNP) component, contains IMP4 domain 7 10 15 29 -------------|--||-||||-||-| 29 [R] COG2137 Uncharacterized protein conserved in bacteria 4 10 12 13 |||--|||||||---------------- 15 [J] COG2157 Ribosomal protein L20A (L18A) 5 10 12 13 ||---|-|||||---------||----- 22 [J] COG2163 Ribosomal protein L14E/L6E/L27E 5 10 13 17 ----|-|----------|--|-|||||| 33 [L] COG2189 Adenine specific DNA methylase Mod 5 10 13 21 --------------|||---|||-|||| 23 [T] COG2205 Osmosensitive K+ channel histidine kinase 7 10 11 13 ------------|||-|--|-||-||-| 35 [T] COG2206 HD-GYP domain 6 10 12 18 |-||-|-------|--|---|-|-|--| 23 [P] COG2212 Multisubunit Na+/H+ antiporter, MnhF subunit 6 10 14 24 |----|-|-----|--||---||-|--| 33 [M] COG2222 Predicted phosphosugar isomerases 5 10 15 26 --|-------|------|---||||||| 56 [R] COG2249 Putative NADPH-quinone reductase (modulator of drug activity B) 3 10 12 14 |||||||||--|---------------- 15 [J] COG2263 Predicted RNA methylase 7 10 11 14 -||-----------|||--||-|-||-- 24 [S] COG2314 Predicted membrane protein 6 10 15 24 --------------||||--|||-||-| 28 [S] COG2350 Uncharacterized protein conserved in bacteria 5 10 12 19 --------------|||---|-|||||| 21 [O] COG2371 Urease accessory protein UreE 7 10 13 17 -||--|--|||---|-|---|---|--- 27 [T] COG2453 Predicted protein-tyrosine phosphatase 6 10 11 13 --|---|-----|-|||-----|-||-| 23 [T] COG2770 FOG: HAMP domain 7 10 12 16 --------------|-||-||||-||-| 19 [E] COG2856 Predicted Zn peptidase 7 10 17 33 ------------|-|--||||---|||| 99 [M] COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins 5 10 18 29 -------------|||-|---||-|||| 46 [M] COG3307 Lipid A core - O-antigen ligase and related enzymes 7 10 12 16 --|------|----||-|--|||-|--| 47 [L] COG3344 Retron-type reverse transcriptase 6 10 10 17 --|-----------|||---|||-||-| 70 [M] COG3409 Putative peptidoglycan-binding domain-containing protein 7 10 11 15 |||-----------|-||--|-|-|--| 23 [R] COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase 5 10 11 16 -||---|||-----------|||-||-- 17 [T] COG3830 ACT domain-containing protein 7 10 17 31 --|---------|---||-|-|--|||| 53 [M] COG4591 ABC-type transport system, involved in lipoprotein release, permease component