y a o g gggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggg 2 2 2 3 --------------------|---||---------------------------------------- 3 [S] COG1306 Uncharacterized conserved protein 2 3 3 3 |-----|---------|------------------------------------------------- 3 [S] COG1700 Uncharacterized conserved protein 3 3 3 3 --------|-------||------------------------------------------------ 3 [L] COG1769 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) 1 3 3 3 -|----|-|--------------------------------------------------------- 6 [R] COG1800 Predicted transglutaminase-like proteases 2 3 3 3 |-------|--------|------------------------------------------------ 3 [S] COG2164 Uncharacterized conserved protein 3 3 3 3 --------|--------|---|-------------------------------------------- 3 [R] COG2316 Predicted hydrolase (HD superfamily) 3 3 3 3 ----------------||---|-------------------------------------------- 3 [S] COG2380 Uncharacterized protein conserved in bacteria 2 2 3 3 ----------------|-------------------------|-----|----------------- 4 [U] COG3031 Type II secretory pathway, component PulC 2 2 3 3 -------------|----------------------------------||---------------- 3 [Q] COG3207 Pyoverdine/dityrosine biosynthesis protein 3 3 3 3 --------|-------|--------------------|---------------------------- 3 [L] COG3337 Uncharacterized protein predicted to be involved in DNA repair 3 3 3 3 ---|-----------------|--------------|----------------------------- 4 [S] COG3403 Uncharacterized conserved protein 3 3 3 3 ----------------|-------------------|-----------|----------------- 6 [T] COG3434 Predicted signal transduction protein containing EAL and modified HD-GYP domains 1 3 3 3 -|---|--|--------------------------------------------------------- 9 [S] COG3466 Putative transposon-encoded protein 2 2 3 3 -------------------------------|----|-----------|----------------- 3 [Q] COG3479 Phenolic acid decarboxylase 1 2 3 3 ------------------------------------------------||------------|--- 4 [S] COG3495 Uncharacterized protein conserved in bacteria 2 3 3 3 -------------------------------------|-----------|------------|--- 3 [S] COG3551 Uncharacterized protein conserved in bacteria 2 2 3 3 -----------------|--------------|----|---------------------------- 3 [L] COG3649 Uncharacterized protein predicted to be involved in DNA repair 2 3 3 3 ---------------------|------------------------------|----------|-- 3 [S] COG3656 Predicted periplasmic protein 3 3 3 3 -----------------|-------------------|-------------------------|-- 3 [G] COG3661 Alpha-glucuronidase 2 3 3 3 -------------|-----------------------------------|-------------|-- 3 [S] COG3673 Uncharacterized conserved protein 3 3 3 3 -------------|----|-----------------------------|----------------- 4 [I] COG3675 Predicted lipase 1 2 3 3 -------------------------------------------------|--|----------|-- 5 [P] COG3746 Phosphate-selective porin 1 2 3 3 ------------------------------------------|---------|---------|--- 6 [S] COG3756 Uncharacterized protein conserved in bacteria 1 2 3 3 ---------------------------------------------------|||------------ 17 [S] COG3792 Uncharacterized protein conserved in bacteria 2 2 3 3 ---------------------|----------------------------------------||-- 4 [S] COG3798 Uncharacterized protein conserved in bacteria 2 3 3 3 -------------------|----------------------------|-------------|--- 3 [Q] COG3805 Aromatic ring-cleaving dioxygenase 1 3 3 3 ||-|-------------------------------------------------------------- 3 [S] COG3815 Predicted membrane protein 1 2 3 3 ----------------------------------------------------|---------||-- 3 [R] COG3818 Predicted acetyltransferase, GNAT superfamily 2 3 3 3 --------|---------------------|-----|----------------------------- 3 [S] COG3863 Uncharacterized distant relative of cell wall-associated hydrolases 3 3 3 3 -----------------|---|--------|----------------------------------- 3 [S] COG3864 Uncharacterized protein conserved in bacteria 3 3 3 3 -----------------|---|--------|----------------------------------- 3 [S] COG3877 Uncharacterized protein conserved in bacteria 2 2 2 3 ------------------|-----------------------------------------|-|--- 4 [S] COG3900 Predicted periplasmic protein 1 2 2 3 -------------------------------------------------|----------|-|--- 4 [S] COG3904 Predicted periplasmic protein 1 1 3 3 ---------------------------------------------|---|--|------------- 3 [R] COG3907 PAP2 (acid phosphatase) superfamily protein 1 2 3 3 ------------------------------------------------||---------|------ 4 [S] COG3915 Uncharacterized protein conserved in bacteria 2 2 2 3 -------------------------------|---------------------------|--|--- 3 [R] COG3919 Predicted ATP-grasp enzyme 1 2 2 3 ------------------------------|---|-|----------------------------- 3 [G] COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation 2 3 3 3 ------------------------------|------|--------|------------------- 3 [R] COG3940 Predicted beta-xylosidase 2 3 3 3 ---------------------|--------|------|---------------------------- 4 [T] COG3947 Response regulator containing CheY-like receiver and SARP domains 1 2 3 3 ----------------------------------------------|-|-----------|----- 4 [R] COG3950 Predicted ATP-binding protein involved in virulence 2 3 3 3 ------------------------------|--|----------------|--------------- 4 [M] COG3955 Exopolysaccharide biosynthesis protein 1 2 2 3 ----------------------------------------------|------------|--|--- 4 [R] COG3964 Predicted amidohydrolase 3 3 3 3 ------------------|--|--------|----------------------------------- 3 [R] COG3968 Uncharacterized protein related to glutamine synthetase 3 3 3 3 ------------------------|-----|-------------------------------|--- 4 [S] COG3976 Uncharacterized protein conserved in bacteria 1 3 3 3 |-------||-------------------------------------------------------- 3 [R] COG4001 Predicted metal-binding protein 1 3 3 3 ||-------|-------------------------------------------------------- 6 [R] COG4007 Predicted dehydrogenase related to H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase 1 3 3 3 ||-------|-------------------------------------------------------- 3 [S] COG4009 Uncharacterized protein conserved in archaea 1 3 3 3 ||-------|-------------------------------------------------------- 3 [S] COG4010 Uncharacterized protein conserved in archaea 1 3 3 3 ||-------|-------------------------------------------------------- 3 [S] COG4013 Uncharacterized protein conserved in archaea 1 3 3 3 ||-------|-------------------------------------------------------- 3 [R] COG4015 Predicted dinucleotide-utilizing enzyme of the ThiF/HesA family 1 3 3 3 ||-------|-------------------------------------------------------- 3 [S] COG4016 Uncharacterized protein conserved in archaea 1 3 3 3 ||-------|-------------------------------------------------------- 3 [S] COG4017 Uncharacterized protein conserved in archaea 1 3 3 3 ||-------|-------------------------------------------------------- 3 [S] COG4018 Uncharacterized protein conserved in archaea 1 3 3 3 ||-------|-------------------------------------------------------- 3 [S] COG4019 Uncharacterized protein conserved in archaea 1 3 3 3 ||-------|-------------------------------------------------------- 3 [S] COG4024 Uncharacterized protein conserved in archaea 1 3 3 3 |------|-|-------------------------------------------------------- 3 [R] COG4026 Uncharacterized protein containing TOPRIM domain, potential nuclease 1 3 3 3 |-------||-------------------------------------------------------- 3 [S] COG4030 Uncharacterized protein conserved in archaea 1 3 3 3 ||-------|-------------------------------------------------------- 3 [S] COG4035 Predicted membrane protein 1 3 3 3 ||-------|-------------------------------------------------------- 3 [S] COG4036 Predicted membrane protein 1 3 3 3 ||-------|-------------------------------------------------------- 3 [S] COG4037 Predicted membrane protein 1 3 3 3 ||-------|-------------------------------------------------------- 3 [S] COG4038 Predicted membrane protein 1 3 3 3 ||-------|-------------------------------------------------------- 3 [S] COG4039 Predicted membrane protein 1 3 3 3 ||-------|-------------------------------------------------------- 3 [S] COG4040 Predicted membrane protein 1 3 3 3 ||-------|-------------------------------------------------------- 3 [S] COG4041 Predicted membrane protein 1 3 3 3 ||-------|-------------------------------------------------------- 3 [S] COG4042 Predicted membrane protein 1 3 3 3 ||-------|-------------------------------------------------------- 3 [S] COG4053 Uncharacterized protein conserved in archaea 1 3 3 3 ||-------|-------------------------------------------------------- 4 [S] COG4066 Uncharacterized protein conserved in archaea 2 2 3 3 ---------|--------------------------------------||---------------- 8 [O] COG4067 Uncharacterized protein conserved in archaea 1 3 3 3 |-------||-------------------------------------------------------- 3 [S] COG4068 Uncharacterized protein containing a Zn-ribbon 1 3 3 3 ||-------|-------------------------------------------------------- 3 [S] COG4071 Uncharacterized protein conserved in archaea 1 3 3 3 ||-------|-------------------------------------------------------- 3 [C] COG4074 H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase 1 3 3 3 ||-------|-------------------------------------------------------- 4 [S] COG4075 Uncharacterized conserved protein, homolog of nitrogen regulatory protein PII 1 3 3 3 ||-------|-------------------------------------------------------- 3 [R] COG4076 Predicted RNA methylase 1 3 3 3 ||-------|-------------------------------------------------------- 3 [S] COG4077 Uncharacterized protein conserved in archaea 1 3 3 3 ||-------|-------------------------------------------------------- 3 [S] COG4078 Predicted membrane protein 1 3 3 3 ||-------|-------------------------------------------------------- 3 [S] COG4084 Uncharacterized protein conserved in archaea 1 3 3 3 ------------------------------------------------------|---|-|----- 3 [M] COG4092 Predicted glycosyltransferase involved in capsule biosynthesis 2 2 2 3 -----------------|----------------|-|----------------------------- 3 [R] COG4112 Predicted phosphoesterase (MutT family) 1 1 3 3 ---------------------------------------------|--||---------------- 3 [R] COG4128 Zonula occludens toxin 2 3 3 3 ---|---------------------------------------------|----------|----- 6 [K] COG4190 Predicted transcriptional regulator 1 1 3 3 ----------------------------------------------|-|--|-------------- 3 [T] COG4192 Signal transduction histidine kinase regulating phosphoglycerate transport system 2 3 3 3 ------------------------------|------|-------------------------|-- 6 [S] COG4200 Uncharacterized protein conserved in bacteria 2 3 3 3 ------------------------------|---|----------------------------|-- 7 [KT] COG4219 Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component 1 2 2 3 ----------------------------------------------------|------|--|--- 6 [L] COG4227 Antirestriction protein 2 3 3 3 ------------------||-------------------------------------------|-- 5 [QP] COG4242 Cyanophycinase and related exopeptidases 3 3 3 3 -------------------|----------------|--------------------------|-- 3 [I] COG4247 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) 2 3 3 3 -------------------|--------------------------------|---------|--- 15 [R] COG4249 Uncharacterized protein containing caspase domain 2 3 3 3 ---|--------------||---------------------------------------------- 4 [T] COG4250 Predicted sensor protein/domain 1 2 3 3 ---------------------------------------------|---|-----|---------- 17 [S] COG4253 Uncharacterized protein conserved in bacteria 2 3 3 3 ------------------|------------------------------|-----|---------- 4 [V] COG4257 Streptogramin lyase 3 3 3 3 -----------|-------|------------------------------------------|--- 4 [S] COG4280 Predicted membrane protein 3 3 3 3 -----------------|-|----------------------------------------|----- 4 [S] COG4288 Uncharacterized protein conserved in bacteria 3 3 3 3 -------------------|-|--------|----------------------------------- 3 [S] COG4295 Uncharacterized protein conserved in bacteria 3 3 3 3 -------------------|-|--------|----------------------------------- 3 [S] COG4296 Uncharacterized protein conserved in bacteria 3 3 3 3 -------------------|-|----------------------------------------|--- 3 [S] COG4298 Uncharacterized protein conserved in bacteria 3 3 3 3 -------------------|-|-----------------------------------------|-- 3 [S] COG4299 Uncharacterized conserved protein 2 3 3 3 ------------------------------------|---------------|--|---------- 3 [G] COG4305 Endoglucanase C-terminal domain/subunit and related proteins 2 3 3 3 ------------------------------|---------------------|--|---------- 3 [S] COG4306 Uncharacterized protein conserved in bacteria 1 3 3 3 ----------------------------------------------------|--|------|--- 3 [S] COG4320 Uncharacterized protein conserved in bacteria 1 3 3 3 ----------------------------------------------------|--|-------|-- 3 [S] COG4322 Uncharacterized protein conserved in bacteria 1 3 3 3 -------------------------------------------------|-----|-------|-- 3 [S] COG4323 Predicted membrane protein 1 3 3 3 -------------------------------------------------|-----|------|--- 3 [R] COG4324 Predicted aminopeptidase 3 3 3 3 -------------------|----------------|-----------|----------------- 3 [R] COG4326 Sporulation control protein 3 3 3 3 -------------------|-----------------|----------------------|----- 3 [S] COG4329 Predicted membrane protein 2 3 3 3 -------------------------------|--------------------|-------|----- 3 [S] COG4334 Uncharacterized protein conserved in bacteria 2 3 3 3 ------------------------------------|--------------|-------|------ 4 [L] COG4335 DNA alkylation repair enzyme 2 3 3 3 -------------------|----------------------------|--------------|-- 3 [S] COG4337 Uncharacterized protein conserved in bacteria 2 3 3 3 -------------------|----------------------------|--------------|-- 3 [S] COG4338 Uncharacterized protein conserved in bacteria 2 3 3 3 -------------------|-----------------------------|------------|--- 3 [S] COG4339 Uncharacterized protein conserved in bacteria 2 3 3 3 -------------------|----------------------------|--------------|-- 3 [S] COG4340 Uncharacterized protein conserved in bacteria 2 2 3 3 ------|----||----------------------------------------------------- 5 [S] COG4342 Uncharacterized protein conserved in archaea 2 3 3 3 -----------|------||---------------------------------------------- 6 [G] COG4354 Predicted bile acid beta-glucosidase 2 3 3 3 -------------|----||---------------------------------------------- 4 [F] COG4360 ATP adenylyltransferase (5',5'''-P-1,P-4-tetraphosphate phosphorylase II) 2 3 3 3 ------------------||-|-------------------------------------------- 4 [S] COG4370 Uncharacterized protein conserved in bacteria 2 3 3 3 ------------------||-|-------------------------------------------- 3 [S] COG4371 Predicted membrane protein 2 3 3 3 ------------------||-|-------------------------------------------- 3 [S] COG4372 Uncharacterized protein conserved in bacteria with the myosin-like domain 2 2 3 3 ---------------------|----------------------|-----|--------------- 3 [R] COG4373 Mu-like prophage FluMu protein gp28 2 2 3 3 ---------------------|-----------------------------------------|-| 3 [S] COG4374 Uncharacterized protein conserved in bacteria 2 2 3 3 ---------------------------------|--|------------------|---------- 3 [S] COG4377 Predicted membrane protein 2 3 3 3 ------------------------------|------|--------------------|------- 3 [S] COG4378 Uncharacterized protein conserved in bacteria 1 2 3 3 --------------------------------------------|-----|---|----------- 3 [R] COG4396 Mu-like prophage host-nuclease inhibitor protein Gam 1 2 3 3 --------------------------------------------|-----|---|----------- 3 [R] COG4397 Mu-like prophage major head subunit gpT 2 3 3 3 ------------------------------|-----|-----------|----------------- 3 [S] COG4412 Uncharacterized protein conserved in bacteria 2 2 3 3 ------------------------------|-------------|-----|--------------- 3 [R] COG4416 Mu-like prophage protein Com 2 2 3 3 -------------------------------------|-------------------------|-| 5 [G] COG4421 Capsular polysaccharide biosynthesis protein 2 3 3 3 ------------------||----------------------------|----------------- 4 [S] COG4446 Uncharacterized protein conserved in bacteria 2 3 3 3 ------------------||-------------------------------------------|-- 3 [R] COG4449 Predicted protease of the Abi (CAAX) family 2 3 3 3 ------------------||----------------------------------------|----- 6 [C] COG4451 Ribulose bisphosphate carboxylase small subunit 1 2 3 3 ----------------------------------------------|--|------------|--- 3 [S] COG4460 Uncharacterized protein conserved in bacteria 1 2 2 3 ------------------------------|---|-|----------------------------- 3 [S] COG4502 Uncharacterized protein conserved in bacteria 1 3 3 3 ------------------------------|------|-|-------------------------- 3 [S] COG4508 Uncharacterized protein conserved in bacteria 1 1 3 3 ---------------------------------------------|---|--|------------- 3 [S] COG4517 Uncharacterized protein conserved in bacteria 1 1 3 3 --------------------------------------------|---|-|--------------- 3 [S] COG4518 Mu-like prophage FluMu protein gp41 1 1 3 3 ---------------------------------------------|--||---------------- 3 [S] COG4519 Uncharacterized protein conserved in bacteria 2 2 3 3 ---|-------------------------------------------------------|---|-- 3 [S] COG4538 Uncharacterized conserved protein 1 1 3 3 ---------------------------------------------|--||---------------- 3 [R] COG4590 ABC-type uncharacterized transport system, permease component 2 2 3 3 ---------------------|-----------------------|--|----------------- 4 [S] COG4628 Uncharacterized conserved protein 1 2 3 3 ------------------------------||----|----------------------------- 4 [G] COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase 2 3 3 3 -------------------|----------|--|-------------------------------- 4 [S] COG4633 Uncharacterized protein conserved in bacteria 2 3 3 3 ------------------||--------------------------------|------------- 7 [S] COG4634 Uncharacterized protein conserved in bacteria 2 3 3 3 -------------------|-----------------------------|----------|----- 5 [R] COG4637 Predicted ATPase 1 2 2 3 ------------------------------|---|-|----------------------------- 4 [S] COG4640 Predicted membrane protein 1 2 2 3 ---------------------------------------------------------|-|--|--- 4 [KL] COG4646 DNA methylase 2 3 3 3 ----------------|--------------------------------|-----|---------- 5 [C] COG4654 Cytochrome c551/c552 2 3 3 3 -------------------|-----------------------------------|------|--- 7 [S] COG4675 Microcystin-dependent protein 2 3 3 3 ------------------------------|------------------------|------|--- 5 [Q] COG4689 Acetoacetate decarboxylase 1 2 3 3 ---------------------------------------------|---|-----|---------- 4 [Q] COG4693 Oxidoreductase (NAD-binding), involved in siderophore biosynthesis 2 3 3 3 -------------------|-----------------------------------|-------|-- 4 [S] COG4704 Uncharacterized protein conserved in bacteria 2 3 3 3 -------------------|-----------------------------------|------|--- 4 [S] COG4705 Uncharacterized membrane-anchored protein conserved in bacteria 1 1 2 3 -------------------------------|--|--|---------------------------- 4 [S] COG4707 Uncharacterized protein conserved in bacteria 1 3 3 3 ----------------------------------------------------|-----||------ 3 [R] COG4710 Predicted DNA-binding protein with an HTH domain 2 3 3 3 ---------------------|--------||---------------------------------- 3 [S] COG4712 Uncharacterized protein conserved in bacteria 1 2 2 3 ------------------------------|||--------------------------------- 3 [S] COG4713 Predicted membrane protein 1 2 3 3 ----------------------------------------------|----|---|---------- 3 [S] COG4714 Uncharacterized membrane-anchored protein conserved in bacteria 3 3 3 3 -------------------|-|--------------------------------------|----- 3 [S] COG4719 Uncharacterized protein conserved in bacteria 1 1 2 3 -------------------------------|-|---|---------------------------- 3 [G] COG4724 Endo-beta-N-acetylglucosaminidase D 3 3 3 3 -------------|-----|----------------------------------------|----- 3 [TK] COG4725 Transcriptional activator, adenine-specific DNA methyltransferase 1 2 3 3 ----------------------------------------------|-----|--|---------- 3 [S] COG4727 Uncharacterized protein conserved in bacteria 2 3 3 3 ------------------------------|------------------|-----|---------- 3 [S] COG4728 Uncharacterized protein conserved in bacteria 2 3 3 3 -------------------|-------------------------|-------------|------ 3 [R] COG4734 Antirestriction protein 1 3 3 3 --|-----||-------------------------------------------------------- 4 [S] COG4739 Uncharacterized protein containing a ferredoxin domain 1 3 3 3 |-|------|-------------------------------------------------------- 3 [R] COG4740 Predicted metalloprotease 1 3 3 3 |-|-----|--------------------------------------------------------- 31 [K] COG4742 Predicted transcriptional regulator 1 3 3 3 --||----|--------------------------------------------------------- 5 [O] COG4745 Predicted membrane-bound mannosyltransferase 1 3 3 3 |-|-----|--------------------------------------------------------- 4 [R] COG4747 ACT domain-containing protein 1 3 3 3 --||----|--------------------------------------------------------- 3 [S] COG4749 Uncharacterized protein conserved in archaea 3 3 3 3 ----------------||--|--------------------------------------------- 3 [S] COG4752 Uncharacterized protein conserved in bacteria 1 1 3 3 ----------|||----------------------------------------------------- 3 [S] COG4755 Uncharacterized protein conserved in archaea 2 2 3 3 --------|-|-|----------------------------------------------------- 3 [R] COG4756 Predicted cation transporter 2 3 3 3 ------------------||------|--------------------------------------- 9 [O] COG4759 Uncharacterized protein conserved in bacteria containing thioredoxin-like domain 2 2 3 3 -------------------|------------------------------------------||-- 7 [R] COG4798 Predicted methyltransferase 1 3 3 3 -||-----|--------------------------------------------------------- 3 [K] COG4800 Predicted transcriptional regulator with an HTH domain 2 3 3 3 --------------------------|-------------------------|----------|-- 8 [S] COG4805 Uncharacterized protein conserved in bacteria 1 1 2 3 -------------------------------|--||------------------------------ 6 [R] COG4814 Uncharacterized protein with an alpha/beta hydrolase fold 2 2 2 3 --------------------------|-------||------------------------------ 6 [S] COG4815 Uncharacterized protein conserved in bacteria 1 1 2 3 -------------------------------|---|-|---------------------------- 6 [S] COG4817 Uncharacterized protein conserved in bacteria 1 3 3 3 -||-----|--------------------------------------------------------- 6 [S] COG4818 Predicted membrane protein 2 2 2 3 -----------------------------------|-|-----------------------|---- 5 [R] COG4821 Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain 3 3 3 3 --------------------|--------------|---------------|-------------- 5 [V] COG4823 Abortive infection bacteriophage resistance protein 3 3 3 3 --|-------|--------|---------------------------------------------- 5 [O] COG4826 Serine protease inhibitor 1 3 3 3 |-|------|-------------------------------------------------------- 5 [R] COG4827 Predicted transporter 3 3 3 3 --|---------------|--|-------------------------------------------- 5 [S] COG4828 Predicted membrane protein 3 3 3 3 --|--------|----|------------------------------------------------- 4 [S] COG4831 Uncharacterized conserved protein 2 3 3 3 -----------------------------------|----------------|---------|--- 4 [S] COG4834 Uncharacterized protein conserved in bacteria 1 3 3 3 --|----||--------------------------------------------------------- 4 [S] COG4854 Predicted membrane protein 1 3 3 3 |-|-----|--------------------------------------------------------- 4 [S] COG4855 Uncharacterized protein conserved in archaea 3 3 3 3 -----------------|-----------------|----------|------------------- 4 [Q] COG4869 Propanediol utilization protein 1 3 3 3 |-|-----|--------------------------------------------------------- 4 [S] COG4871 Uncharacterized protein conserved in archaea 1 1 1 3 ----------------------------------|||----------------------------- 3 [S] COG4873 Uncharacterized protein conserved in bacteria 2 3 3 3 --------------------|---------------------------|------|---------- 3 [S] COG4874 Uncharacterized protein conserved in bacteria containing a pentein-type domain 1 3 3 3 ----------------------------------------------------|--|-----|---- 3 [S] COG4875 Uncharacterized protein conserved in bacteria with a cystatin-like fold 1 1 1 3 ----------------------------------|||----------------------------- 3 [S] COG4876 Uncharacterized protein conserved in bacteria 3 3 3 3 --------------------------|------|-------------------------|------ 3 [S] COG4877 Uncharacterized protein conserved in bacteria 3 3 3 3 -----------------|--|---------|----------------------------------- 4 [S] COG4878 Uncharacterized protein conserved in bacteria 1 1 3 3 ----------|||----------------------------------------------------- 3 [S] COG4879 Uncharacterized protein conserved in archaea 2 3 3 3 -|------|-|------------------------------------------------------- 3 [R] COG4880 Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats 2 2 3 3 --------|-|-|----------------------------------------------------- 3 [S] COG4881 Predicted membrane protein 1 1 3 3 ----------|||----------------------------------------------------- 3 [R] COG4882 Predicted aminopeptidase, Iap family 1 3 3 3 |-|-----|--------------------------------------------------------- 3 [S] COG4883 Uncharacterized protein conserved in archaea 3 3 3 3 --------------------|--------------|------|----------------------- 3 [S] COG4884 Uncharacterized protein conserved in bacteria 1 3 3 3 --||----|--------------------------------------------------------- 3 [S] COG4885 Uncharacterized protein conserved in archaea 1 3 3 3 -||------|-------------------------------------------------------- 3 [R] COG4887 Uncharacterized metal-binding protein conserved in archaea 1 2 3 3 ----------------------------------------------|-|------------|---- 3 [S] COG4890 Predicted outer membrane lipoprotein 2 3 3 3 |-|---------------------------|----------------------------------- 3 [R] COG4892 Predicted heme/steroid binding protein 1 2 3 3 ----------------------------------------------|--|-----------|---- 3 [S] COG4893 Uncharacterized protein conserved in bacteria 3 3 3 3 --|------------------|--------------|----------------------------- 3 [S] COG4895 Uncharacterized conserved protein 1 1 1 3 ----------------------------------|||----------------------------- 3 [S] COG4896 Uncharacterized protein conserved in bacteria 1 1 1 3 ----------------------------------|||----------------------------- 3 [S] COG4897 Uncharacterized protein conserved in bacteria 2 2 3 3 ---------------------------------|-|------------------------|----- 3 [S] COG4898 Uncharacterized protein conserved in bacteria 2 3 3 3 --------------------------|---------------------------|--------|-- 3 [S] COG4899 Uncharacterized protein conserved in bacteria 1 1 3 3 ----------|||----------------------------------------------------- 3 [R] COG4900 Predicted metallopeptidase 1 3 3 3 -||----|---------------------------------------------------------- 3 [S] COG4902 Uncharacterized protein conserved in archaea 1 1 1 3 ----------------------------------|||----------------------------- 3 [K] COG4903 Genetic competence transcription factor 2 2 3 3 --------|-|-|----------------------------------------------------- 3 [S] COG4904 Uncharacterized protein conserved in archaea 1 2 3 3 ------------------------------||---|------------------------------ 3 [S] COG4905 Predicted membrane protein 1 3 3 3 |-|----|---------------------------------------------------------- 3 [S] COG4906 Predicted membrane protein 2 3 3 3 -||-----------------|--------------------------------------------- 3 [S] COG4907 Predicted membrane protein 2 3 3 3 -----------------------------------|----------|---------------|--- 3 [Q] COG4909 Propanediol dehydratase, large subunit 2 3 3 3 -----------------------------------|----------|---------------|--- 3 [Q] COG4910 Propanediol dehydratase, small subunit 2 2 3 3 ----------||----|------------------------------------------------- 3 [S] COG4911 Uncharacterized conserved protein 2 2 3 3 --------------------------|------------------|------|------------- 3 [S] COG4913 Uncharacterized protein conserved in bacteria 1 1 3 3 ----------|||----------------------------------------------------- 3 [R] COG4914 Predicted nucleotidyltransferase 2 3 3 3 ------------------|------------------------------------|-----|---- 3 [S] COG4916 Uncharacterized protein containing a TIR (Toll-Interleukin 1-resistance) domain 1 1 2 3 -------------------------------|---||----------------------------- 3 [S] COG4918 Uncharacterized protein conserved in bacteria 1 1 3 3 ----------|||----------------------------------------------------- 3 [J] COG4919 Ribosomal protein S30 1 1 3 3 ----------|||----------------------------------------------------- 3 [S] COG4920 Predicted membrane protein 1 3 3 3 -||------|-------------------------------------------------------- 3 [S] COG4921 Uncharacterized protein conserved in archaea 3 3 3 3 --|--------------|--------------------------------------------|--- 3 [S] COG4923 Uncharacterized conserved protein 2 2 3 3 --------------------------|------------------|------|------------- 3 [S] COG4924 Uncharacterized protein conserved in bacteria 2 3 3 3 --|-------------------------------------------------|--|---------- 3 [S] COG4925 Uncharacterized conserved protein 3 3 3 3 --------------------|-------------|-------------------------|----- 3 [R] COG4927 Predicted choloylglycine hydrolase 3 3 3 3 --|-------|-----------------------------------|------------------- 3 [O] COG4930 Predicted ATP-dependent Lon-type protease 1 1 2 3 -------------------------------|---|-|---------------------------- 9 [M] COG4932 Predicted outer membrane protein 2 3 3 3 ------------------------------|----|----------|------------------- 3 [TK] COG4936 Predicted sensor domain 1 3 3 3 |||--------------------------------------------------------------- 3 [J] COG4937 Predicted regulatory domain of prephenate dehydrogenase 3 3 3 3 ----------|------------------------|------------|----------------- 3 [S] COG4938 Uncharacterized conserved protein 3 3 3 3 --------------------|---|----------|------------------------------ 3 [S] COG4939 Major membrane immunogen, membrane-anchored lipoprotein 2 3 3 3 ----|--|--|------------------------------------------------------- 4 [G] COG4945 Membrane-anchored protein predicted to be involved in regulation of amylopullulanase 2 2 2 3 ---------------------------------|-------------------------|--|--- 4 [S] COG4947 Uncharacterized protein conserved in bacteria 1 2 2 3 -------------------------------------------------------|---|--|--- 3 [S] COG4954 Uncharacterized protein conserved in bacteria 2 2 3 3 --------------------|------------------------|-----|-------------- 3 [S] COG4984 Predicted membrane protein 1 1 3 3 ---------------------------------------------|--||---------------- 3 [P] COG4985 ABC-type phosphate transport system, auxiliary component 2 3 3 3 ------------------------------|----|-------------------|---------- 3 [S] COG4994 Uncharacterized protein conserved in bacteria 2 3 3 3 ------------------||-------------------------------------------|-- 17 [S] COG4995 Uncharacterized protein conserved in bacteria 1 1 3 3 ----------|||----------------------------------------------------- 3 [R] COG4996 Predicted phosphatase 2 2 3 3 ---------||-|----------------------------------------------------- 3 [L] COG4998 Predicted endonuclease (RecB family) 1 2 3 3 -------------------------------------------------------|---|---|-- 3 [T] COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain 1 2 3 3 --------------------------------------------|-----|---|----------- 5 [R] COG5005 Mu-like prophage protein gpG 3 3 3 3 ---------||------|------------------------------------------------ 3 [R] COG5014 Predicted Fe-S oxidoreductase 3 3 3 3 --------------|---------------------|------------|---------------- 3 [R] COG5018 Inhibitor of the KinA pathway to sporulation, predicted exonuclease 2 3 3 3 -------------|||-------------------------------------------------- 17 [DZ] COG5019 Septin family protein 2 3 3 3 -------------|||-------------------------------------------------- 16 [G] COG5020 Mannosyltransferase 2 3 3 3 -------------|||-------------------------------------------------- 14 [O] COG5021 Ubiquitin-protein ligase 2 3 3 3 -------------|||-------------------------------------------------- 12 [Z] COG5022 Myosin heavy chain 2 3 3 3 -------------|||-------------------------------------------------- 11 [Z] COG5023 Tubulin 2 3 3 3 -------------|||-------------------------------------------------- 16 [D] COG5024 Cyclin 2 3 3 3 -------------|||-------------------------------------------------- 10 [K] COG5025 Transcription factor of the Forkhead/HNF3 family 2 3 3 3 -------------|||-------------------------------------------------- 7 [B] COG5027 Histone acetyltransferase (MYST family) 2 3 3 3 -------------|||-------------------------------------------------- 7 [U] COG5028 Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 2 3 3 3 -------------|||-------------------------------------------------- 7 [O] COG5029 Prenyltransferase, beta subunit 2 3 3 3 -------------|||-------------------------------------------------- 7 [U] COG5030 Clathrin adaptor complex, small subunit 2 3 3 3 -------------||----|---------------------------------------------- 6 [H] COG5031 Uncharacterized protein involved in ubiquinone biosynthesis 2 3 3 3 -------------|||-------------------------------------------------- 22 [TDBLU] COG5032 Phosphatidylinositol kinase and protein kinases of the PI-3 kinase family 2 3 3 3 -------------|||-------------------------------------------------- 6 [K] COG5033 Transcription initiation factor IIF, auxiliary subunit 2 3 3 3 -------------|||-------------------------------------------------- 6 [B] COG5034 Chromatin remodeling protein, contains PhD zinc finger 2 3 3 3 -------------|||-------------------------------------------------- 6 [DKT] COG5035 Cell cycle control protein 2 3 3 3 -------------|||-------------------------------------------------- 6 [P] COG5036 SPX domain-containing protein involved in vacuolar polyphosphate accumulation 2 3 3 3 -------------|||-------------------------------------------------- 6 [TG] COG5037 Gluconate transport-inducing protein 2 3 3 3 -------------|||-------------------------------------------------- 7 [R] COG5038 Ca2+-dependent lipid-binding protein, contains C2 domain 3 3 3 3 --------------|----|----------------|----------------------------- 6 [GM] COG5039 Exopolysaccharide biosynthesis protein 2 3 3 3 -------------|||-------------------------------------------------- 5 [T] COG5040 14-3-3 family protein 2 3 3 3 -------------|||-------------------------------------------------- 5 [TDK] COG5041 Casein kinase II, beta subunit 2 3 3 3 -------------|||-------------------------------------------------- 5 [U] COG5043 Vacuolar protein sorting-associated protein 2 3 3 3 -------------|||-------------------------------------------------- 6 [O] COG5044 RAB proteins geranylgeranyltransferase component A (RAB escort protein) 2 3 3 3 -------------|||-------------------------------------------------- 5 [J] COG5045 Ribosomal protein S10E 2 3 3 3 -------------|||-------------------------------------------------- 5 [O] COG5046 Protein involved in Mod5 protein sorting 2 3 3 3 -------------|||-------------------------------------------------- 5 [U] COG5047 Vesicle coat complex COPII, subunit SEC23 2 3 3 3 -------------|||-------------------------------------------------- 48 [R] COG5048 FOG: Zn-finger 2 3 3 3 -------------|||-------------------------------------------------- 5 [LDA] COG5049 5'-3' exonuclease 2 3 3 3 -------------|||-------------------------------------------------- 5 [J] COG5051 Ribosomal protein L36E 2 3 3 3 -------------|||-------------------------------------------------- 5 [U] COG5052 Protein involved in membrane traffic 2 3 3 3 -------------|||-------------------------------------------------- 5 [J] COG5053 Translation initiation factor 4E (eIF-4E) 2 3 3 3 -------------|||-------------------------------------------------- 5 [O] COG5054 Mitochondrial sulfhydryl oxidase involved in the biogenesis of cytosolic Fe/S proteins 2 3 3 3 -------------|||-------------------------------------------------- 5 [L] COG5055 Recombination DNA repair protein (RAD52 pathway) 2 3 3 3 -------------|||-------------------------------------------------- 5 [I] COG5056 Acyl-CoA cholesterol acyltransferase 2 3 3 3 -------------|||-------------------------------------------------- 5 [DT] COG5057 Phosphotyrosyl phosphatase activator 2 3 3 3 -------------|||-------------------------------------------------- 5 [U] COG5058 Protein transporter of the TRAM (translocating chain-associating membrane) superfamily, longevity assurance factor 2 3 3 3 -------------|||-------------------------------------------------- 22 [Z] COG5059 Kinesin-like protein 2 3 3 3 -------------|||-------------------------------------------------- 4 [OU] COG5061 Oxidoreductin, endoplasmic reticulum membrane-associated protein involved in disulfide bond formation 2 3 3 3 -------------|||-------------------------------------------------- 4 [S] COG5062 Uncharacterized membrane protein 2 3 3 3 -------------|||-------------------------------------------------- 4 [R] COG5063 CCCH-type Zn-finger protein 2 3 3 3 -------------|||-------------------------------------------------- 4 [U] COG5064 Karyopherin (importin) alpha 2 3 3 3 -------------|||-------------------------------------------------- 4 [P] COG5065 Protein involved in inorganic phosphate transport 2 3 3 3 -------------|||-------------------------------------------------- 4 [U] COG5066 VAMP-associated protein involved in inositol metabolism 2 3 3 3 -------------|||-------------------------------------------------- 4 [LD] COG5067 Protein kinase essential for the initiation of DNA replication 2 3 3 3 -------------|||-------------------------------------------------- 8 [K] COG5068 Regulator of arginine metabolism and related MADS box-containing transcription factors 2 3 3 3 -------------|||-------------------------------------------------- 4 [Z] COG5069 Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) 2 3 3 3 -------------|||-------------------------------------------------- 5 [GOU] COG5070 Nucleotide-sugar transporter 2 3 3 3 -------------|||-------------------------------------------------- 4 [O] COG5071 26S proteasome regulatory complex component 2 3 3 3 -------------|||-------------------------------------------------- 4 [D] COG5072 Serine/threonine kinase of the haspin family 2 3 3 3 -------------|||-------------------------------------------------- 5 [U] COG5073 Vacuolar import and degradation protein 2 3 3 3 -------------|||-------------------------------------------------- 4 [U] COG5074 t-SNARE complex subunit, syntaxin 2 3 3 3 -------------|||-------------------------------------------------- 4 [S] COG5075 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 21 [BK] COG5076 Transcription factor involved in chromatin remodeling, contains bromodomain 2 3 3 3 -------------|||-------------------------------------------------- 4 [O] COG5077 Ubiquitin carboxyl-terminal hydrolase 2 3 3 3 -------------|||-------------------------------------------------- 36 [O] COG5078 Ubiquitin-protein ligase 2 3 3 3 -------------|||-------------------------------------------------- 4 [UD] COG5079 Nuclear protein export factor 2 3 3 3 -------------|||-------------------------------------------------- 5 [U] COG5080 Rab GTPase interacting factor, Golgi membrane protein 2 3 3 3 -------------|||-------------------------------------------------- 4 [S] COG5081 Predicted membrane protein 2 3 3 3 -------------|||-------------------------------------------------- 9 [OU] COG5082 Arginine methyltransferase-interacting protein, contains RING Zn-finger 2 3 3 3 -------------|||-------------------------------------------------- 10 [R] COG5084 Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin family Zn-finger proteins 2 3 3 3 -------------|||-------------------------------------------------- 4 [S] COG5085 Predicted membrane protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5086 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5087 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [R] COG5088 Rad5p-binding protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5090 Transcription initiation factor IIF, small subunit (RAP30) 2 3 3 3 -------------|||-------------------------------------------------- 3 [R] COG5091 Suppressor of G2 allele of skp1 and related proteins 2 3 3 3 -------------|||-------------------------------------------------- 3 [I] COG5092 N-myristoyl transferase 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5093 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5094 Transcription initiation factor TFIID, subunit TAF9 (also component of histone acetyltransferase SAGA) 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5095 Transcription initiation factor TFIID, subunit TAF6 (also component of histone acetyltransferase SAGA) 2 3 3 3 -------------|||-------------------------------------------------- 10 [U] COG5096 Vesicle coat complex, various subunits 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5097 RNA polymerase II transcriptional regulation mediator 2 3 3 3 -------------|||-------------------------------------------------- 3 [BD] COG5098 Chromosome condensation complex Condensin, subunit D2 2 3 3 3 -------------|||-------------------------------------------------- 13 [J] COG5099 RNA-binding protein of the Puf family, translational repressor 2 3 3 3 -------------|||-------------------------------------------------- 3 [U] COG5100 Nuclear pore protein 2 3 3 3 -------------|||-------------------------------------------------- 6 [U] COG5101 Nuclear transport receptor CRM1/MSN5 (importin beta superfamily) 2 3 3 3 -------------|||-------------------------------------------------- 3 [U] COG5102 Membrane protein involved in ER to Golgi transport 2 3 3 3 -------------|||-------------------------------------------------- 3 [DK] COG5103 Cell division control protein, negative regulator of transcription 2 3 3 3 -------------|||-------------------------------------------------- 3 [A] COG5104 Splicing factor 2 3 3 3 -------------|||-------------------------------------------------- 3 [D] COG5105 Mitotic inducer, protein phosphatase 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5106 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [A] COG5107 Pre-mRNA 3'-end processing (cleavage and polyadenylation) factor 2 3 3 3 -------------||--------------------------------------------|------ 3 [K] COG5108 Mitochondrial DNA-directed RNA polymerase 2 3 3 3 -------------|||-------------------------------------------------- 3 [R] COG5109 Uncharacterized conserved protein, contains RING Zn-finger 2 3 3 3 -------------|||-------------------------------------------------- 3 [O] COG5110 26S proteasome regulatory complex component 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5111 DNA-directed RNA polymerase III, subunit C34 2 3 3 3 -------------|||-------------------------------------------------- 3 [R] COG5112 U1-like Zn-finger-containing protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [O] COG5113 Ubiquitin fusion degradation protein 2 2 3 3 3 -------------|||-------------------------------------------------- 3 [B] COG5114 Histone acetyltransferase complex SAGA/ADA, subunit ADA2 2 3 3 3 -------------|||-------------------------------------------------- 3 [O] COG5116 26S proteasome regulatory complex component 2 3 3 3 -------------|||-------------------------------------------------- 3 [JU] COG5117 Protein involved in the nuclear export of pre-ribosomes 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5118 Transcription initiation factor TFIIIB, Bdp1 subunit 2 3 3 3 -------------||----|---------------------------------------------- 3 [R] COG5119 Uncharacterized protein, contains ParB-like nuclease domain 2 3 3 3 -------------|||-------------------------------------------------- 3 [U] COG5120 Membrane protein involved in Golgi transport 2 3 3 3 -------------|||-------------------------------------------------- 3 [U] COG5122 Transport protein particle (TRAPP) complex subunit 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5123 Transcription initiation factor IIA, gamma subunit 2 3 3 3 -------------|||-------------------------------------------------- 3 [DR] COG5124 Protein predicted to be involved in meiotic recombination 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5125 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [C] COG5127 Vacuolar H+-ATPase V1 sector, subunit C 2 3 3 3 -------------|||-------------------------------------------------- 3 [U] COG5128 Transport protein particle (TRAPP) complex subunit 2 3 3 3 -------------|||-------------------------------------------------- 3 [R] COG5129 Nuclear protein with HMG-like acidic region 2 3 3 3 -------------|||-------------------------------------------------- 3 [UT] COG5130 Prenylated rab acceptor 1 and related proteins 2 3 3 3 -------------|||-------------------------------------------------- 3 [KD] COG5132 Cell cycle control protein, G10 family 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5133 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5134 Uncharacterized conserved protein 2 3 3 3 -------------||----|---------------------------------------------- 3 [S] COG5135 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [A] COG5136 U1 snRNP-specific protein C 2 3 3 3 -------------|||-------------------------------------------------- 3 [KB] COG5137 Histone chaperone involved in gene silencing 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5138 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5139 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [O] COG5140 Ubiquitin fusion-degradation protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [R] COG5141 PHD zinc finger-containing protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [L] COG5142 Oxidation resistance protein 2 3 3 3 -------------|||-------------------------------------------------- 10 [U] COG5143 Synaptobrevin/VAMP-like protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [KL] COG5144 RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB2 2 3 3 3 -------------|||-------------------------------------------------- 3 [L] COG5145 DNA excision repair protein 2 3 3 3 -------------||-------------------|------------------------------- 3 [H] COG5146 Pantothenate kinase, acetyl-CoA regulated 2 3 3 3 -------------|||-------------------------------------------------- 10 [KAD] COG5147 Myb superfamily proteins, including transcription factors and mRNA splicing factors 2 3 3 3 -------------|||-------------------------------------------------- 3 [O] COG5148 26S proteasome regulatory complex, subunit RPN10/PSMD4 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5149 Transcription initiation factor IIA, large chain 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5150 Class 2 transcription repressor NC2, beta subunit (Dr1) 2 3 3 3 -------------|||-------------------------------------------------- 3 [KL] COG5151 RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit SSL1 2 3 3 3 -------------|||-------------------------------------------------- 3 [R] COG5152 Uncharacterized conserved protein, contains RING and CCCH-type Zn-fingers 2 3 3 3 -------------|||-------------------------------------------------- 3 [UI] COG5153 Putative lipase essential for disintegration of autophagic bodies inside the vacuole 2 3 3 3 -------------|||-------------------------------------------------- 3 [J] COG5154 RNA-binding protein required for 60S ribosomal subunit biogenesis 2 3 3 3 -------------|||-------------------------------------------------- 3 [DO] COG5155 Separase, a protease involved in sister chromatid separation 2 3 3 3 -------------|||-------------------------------------------------- 3 [DO] COG5156 Anaphase-promoting complex (APC), subunit 10 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5157 RNA polymerase II assessory factor 2 3 3 3 -------------|||-------------------------------------------------- 11 [U] COG5158 Proteins involved in synaptic transmission and general secretion, Sec1 family 2 3 3 3 -------------|||-------------------------------------------------- 3 [O] COG5159 26S proteasome regulatory complex component 2 3 3 3 -------------|||-------------------------------------------------- 5 [O] COG5160 Protease, Ulp1 family 2 3 3 3 -------------|||-------------------------------------------------- 3 [A] COG5161 Pre-mRNA cleavage and polyadenylation specificity factor 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5162 Transcription initiation factor TFIID, subunit TAF10 (also component of histone acetyltransferase SAGA) 2 3 3 3 -------------|||-------------------------------------------------- 3 [J] COG5163 Protein required for biogenesis of the 60S ribosomal subunit 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5164 Transcription elongation factor 2 3 3 3 -------------|||-------------------------------------------------- 3 [KLB] COG5165 Nucleosome-binding factor SPN, POB3 subunit 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5166 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [U] COG5167 Protein involved in vacuole import and degradation 2 3 3 3 -------------|||-------------------------------------------------- 10 [K] COG5169 Heat shock transcription factor 2 3 3 3 -------------|||-------------------------------------------------- 3 [T] COG5170 Serine/threonine protein phosphatase 2A, regulatory subunit 2 3 3 3 -------------|||-------------------------------------------------- 3 [U] COG5171 Ran GTPase-activating protein (Ran-binding protein) 2 3 3 3 -------------|||-------------------------------------------------- 3 [U] COG5173 Exocyst complex subunit SEC6 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5174 Transcription initiation factor IIE, beta subunit 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5175 Transcriptional repressor 2 3 3 3 -------------|||-------------------------------------------------- 3 [A] COG5176 Splicing factor (branch point binding protein) 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5177 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [A] COG5178 U5 snRNP spliceosome subunit 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5179 Transcription initiation factor TFIID, subunit TAF1 2 3 3 3 -------------|||-------------------------------------------------- 3 [A] COG5180 Protein interacting with poly(A)-binding protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [A] COG5181 U2 snRNP spliceosome subunit 2 3 3 3 -------------|||-------------------------------------------------- 3 [A] COG5182 Splicing factor 3b, subunit 2 2 3 3 3 -------------|||-------------------------------------------------- 3 [A] COG5183 Protein involved in mRNA turnover and stability 2 3 3 3 -------------|||-------------------------------------------------- 3 [D] COG5185 Protein involved in chromosome segregation, interacts with SMC proteins 2 3 3 3 -------------|||-------------------------------------------------- 3 [A] COG5186 Poly(A) polymerase 2 3 3 3 -------------|||-------------------------------------------------- 3 [O] COG5187 26S proteasome regulatory complex component, contains PCI domain 2 3 3 3 -------------|||-------------------------------------------------- 3 [A] COG5188 Splicing factor 3a, subunit 3 2 3 3 3 -------------|||-------------------------------------------------- 3 [KD] COG5189 Putative transcriptional repressor regulating G2/M transition 2 3 3 3 -------------|||-------------------------------------------------- 12 [K] COG5190 TFIIF-interacting CTD phosphatases, including NLI-interacting factor 2 3 3 3 -------------|||-------------------------------------------------- 3 [R] COG5191 Uncharacterized conserved protein, contains HAT (Half-A-TPR) repeat 2 3 3 3 -------------|||-------------------------------------------------- 3 [J] COG5192 GTP-binding protein required for 40S ribosome biogenesis 2 3 3 3 -------------|||-------------------------------------------------- 6 [OJ] COG5193 La protein, small RNA-binding pol III transcript stabilizing protein and related La-motif-containing proteins involved in translation 2 3 3 3 -------------|||-------------------------------------------------- 5 [OD] COG5194 Component of SCF ubiquitin ligase and anaphase-promoting complex 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5195 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [U] COG5196 ER lumen protein retaining receptor 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5197 Predicted membrane protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [R] COG5198 Protein tyrosine phosphatase-like protein (contains Pro instead of catalytic Arg) 2 3 3 3 -------------|||-------------------------------------------------- 3 [Z] COG5199 Calponin 2 3 3 3 -------------|||-------------------------------------------------- 3 [A] COG5200 U1 snRNP component, mediates U1 snRNP association with cap-binding complex 2 3 3 3 -------------|||-------------------------------------------------- 3 [O] COG5201 SCF ubiquitin ligase, SKP1 component 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5202 Predicted membrane protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5204 Transcription elongation factor SPT4 2 3 3 3 -------------|||-------------------------------------------------- 3 [O] COG5206 Glycosylphosphatidylinositol transamidase (GPIT), subunit GPI8 2 3 3 3 -------------|||-------------------------------------------------- 3 [O] COG5207 Isopeptidase T 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5208 CCAAT-binding factor, subunit C 2 3 3 3 -------------|||-------------------------------------------------- 3 [R] COG5209 Uncharacterized protein involved in cell differentiation/sexual development 2 3 3 3 -------------|||-------------------------------------------------- 25 [R] COG5210 GTPase-activating protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5211 RNA polymerase II-interacting protein involved in transcription start site selection 2 3 3 3 -------------||------------------------------|-------------------- 3 [T] COG5212 Low-affinity cAMP phosphodiesterase 2 3 3 3 -------------|||-------------------------------------------------- 3 [A] COG5213 Polyadenylation factor I complex, subunit FIP1 2 3 3 3 -------------|||-------------------------------------------------- 3 [L] COG5214 DNA polymerase alpha-primase complex, polymerase-associated subunit B 2 3 3 3 -------------|||-------------------------------------------------- 3 [U] COG5215 Karyopherin (importin) beta 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5216 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [DZ] COG5217 Microtubule-binding protein involved in cell cycle control 2 3 3 3 -------------|||-------------------------------------------------- 3 [BD] COG5218 Chromosome condensation complex Condensin, subunit G 2 3 3 3 -------------|||-------------------------------------------------- 3 [R] COG5219 Uncharacterized conserved protein, contains RING Zn-finger 2 3 3 3 -------------|||-------------------------------------------------- 3 [DKL] COG5220 Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB3 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5221 Dopey and related predicted leucine zipper transcription factors 2 3 3 3 -------------|||-------------------------------------------------- 3 [R] COG5222 Uncharacterized conserved protein, contains RING Zn-finger 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5223 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5224 CCAAT-binding factor, subunit B 2 3 3 3 -------------|||-------------------------------------------------- 3 [J] COG5225 Uncharacterized protein involved in ribosome biogenesis 2 3 3 3 -------------|||-------------------------------------------------- 3 [A] COG5226 mRNA capping enzyme, guanylyltransferase (alpha) subunit 2 3 3 3 -------------|||-------------------------------------------------- 3 [O] COG5227 Ubiquitin-like protein (sentrin) 2 3 3 3 -------------|||-------------------------------------------------- 3 [A] COG5228 mRNA deadenylase subunit 2 3 3 3 -------------|||-------------------------------------------------- 3 [BD] COG5229 Chromosome condensation complex Condensin, subunit H 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5230 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [C] COG5231 Vacuolar H+-ATPase V1 sector, subunit H 2 3 3 3 -------------|||-------------------------------------------------- 3 [U] COG5232 Preprotein translocase subunit Sec62 2 3 3 3 -------------|||-------------------------------------------------- 3 [U] COG5233 Peripheral Golgi membrane protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [OZ] COG5234 Beta-tubulin folding cofactor D 2 3 3 3 -------------|||-------------------------------------------------- 3 [L] COG5235 Single-stranded DNA-binding replication protein A (RPA), medium (30 kD) subunit 2 3 3 3 -------------|||-------------------------------------------------- 3 [R] COG5236 Uncharacterized conserved protein, contains RING Zn-finger 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5237 Predicted membrane protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [TA] COG5238 Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport 2 3 3 3 -------------|||-------------------------------------------------- 7 [A] COG5239 mRNA deadenylase, exonuclease subunit and related nucleases 2 3 3 3 -------------|||-------------------------------------------------- 3 [U] COG5240 Vesicle coat complex COPI, gamma subunit 2 3 3 3 -------------|||-------------------------------------------------- 3 [L] COG5241 Nucleotide excision repair endonuclease NEF1, RAD10 subunit 2 3 3 3 -------------|||-------------------------------------------------- 3 [KL] COG5242 RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB4 2 3 3 3 -------------|||-------------------------------------------------- 3 [O] COG5243 HRD ubiquitin ligase complex, ER membrane component 2 3 3 3 -------------|||-------------------------------------------------- 3 [D] COG5244 Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B 2 3 3 3 -------------|||-------------------------------------------------- 3 [Z] COG5245 Dynein, heavy chain 2 3 3 3 -------------|||-------------------------------------------------- 3 [A] COG5246 Splicing factor 3a, subunit 2 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5247 Class 2 transcription repressor NC2, alpha subunit (DRAP1 homolog) 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5248 Transcription initiation factor TFIID, subunit TAF13 2 3 3 3 -------------|||-------------------------------------------------- 3 [U] COG5249 Golgi protein involved in Golgi-to-ER retrieval 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5250 RNA polymerase II, fourth largest subunit 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5251 Transcription initiation factor TFIID, subunit TAF11 2 3 3 3 -------------|||-------------------------------------------------- 3 [R] COG5252 Uncharacterized conserved protein, contains CCCH-type Zn-finger protein 2 3 3 3 -------------|||-------------------------------------------------- 5 [T] COG5253 Phosphatidylinositol-4-phosphate 5-kinase 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5254 Predicted membrane protein 2 3 3 3 -------------|||-------------------------------------------------- 5 [BK] COG5259 RSC chromatin remodeling complex subunit RSC8 2 3 3 3 -------------|||-------------------------------------------------- 9 [L] COG5260 DNA polymerase sigma 2 3 3 3 -------------|||-------------------------------------------------- 4 [DT] COG5261 Protein involved in regulation of cellular morphogenesis/cytokinesis 2 3 3 3 -------------|||-------------------------------------------------- 7 [B] COG5262 Histone H2A 1 2 2 3 ------------------------------||-|-------------------------------- 17 [R] COG5263 FOG: Glucan-binding domain (YG repeat) 2 3 3 3 -------------|||-------------------------------------------------- 8 [O] COG5264 Vacuolar transporter chaperone 2 3 3 3 -------------|||-------------------------------------------------- 3 [JO] COG5269 Ribosome-associated chaperone zuotin 2 3 3 3 -------------|||-------------------------------------------------- 3 [R] COG5271 AAA ATPase containing von Willebrand factor type A (vWA) domain 2 3 3 3 -------------|||-------------------------------------------------- 22 [O] COG5272 Ubiquitin 2 3 3 3 -------------|||-------------------------------------------------- 17 [R] COG5273 Uncharacterized protein containing DHHC-type Zn finger 2 3 3 3 -------------|||-------------------------------------------------- 12 [CI] COG5274 Cytochrome b involved in lipid metabolism 2 3 3 3 -------------|||-------------------------------------------------- 3 [R] COG5275 BRCT domain type II 3 3 3 3 --|--------------|---------------------------|-------------------- 4 [S] COG5276 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 23 [Z] COG5277 Actin and related proteins 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5290 IkappaB kinase complex, IKAP component 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5291 Predicted membrane protein 3 3 3 3 -------------------|----------------|---------------|------------- 3 [S] COG5293 Uncharacterized protein conserved in bacteria 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5296 Transcription factor involved in TATA site selection and in elongation by RNA polymerase II 2 2 2 3 -----------------------------------||------------------|---------- 3 [S] COG5298 Uncharacterized protein conserved in bacteria 1 2 3 3 ----------------------------------------------|--|-----|---------- 4 [R] COG5301 Phage-related tail fibre protein 2 2 3 3 ------------------|--------------------------------------------|-| 4 [S] COG5304 Uncharacterized protein conserved in bacteria 2 3 3 3 -------------|||-------------------------------------------------- 4 [U] COG5308 Nuclear pore complex subunit 2 3 3 3 -------------||----------------------------------|---------------- 6 [G] COG5309 Exo-beta-1,3-glucanase 3 3 3 3 --|------------------|-----------------------------------------|-- 6 [S] COG5316 Uncharacterized conserved protein 2 3 3 3 -------------||-----|--------------------------------------------- 3 [S] COG5324 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 6 [U] COG5325 t-SNARE complex subunit, syntaxin 2 3 3 3 -------------|||-------------------------------------------------- 11 [T] COG5329 Phosphoinositide polyphosphatase (Sac family) 2 3 3 3 -------------|||-------------------------------------------------- 9 [DKL] COG5333 Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, cyclin H subunit 3 3 3 3 --|-----------------------|---------|----------------------------- 4 [M] COG5337 Spore coat assembly protein 2 3 3 3 -------------|||-------------------------------------------------- 14 [U] COG5347 GTPase-activating protein that regulates ARFs (ADP-ribosylation factors), involved in ARF-mediated vesicular transport 1 2 2 3 -------------------------------------------------|---------|--|--- 3 [S] COG5351 Uncharacterized protein conserved in bacteria 2 3 3 3 -------------|||-------------------------------------------------- 5 [R] COG5354 Uncharacterized protein, contains Trp-Asp (WD) repeat 2 3 3 3 -------------|||-------------------------------------------------- 4 [R] COG5366 Protein involved in propagation of M2 dsRNA satellite of L-A virus 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5369 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 5 [GO] COG5371 Golgi nucleoside diphosphatase 2 3 3 3 -------------|||-------------------------------------------------- 5 [S] COG5374 Uncharacterized conserved protein 2 3 3 3 -|-----|----|----------------------------------------------------- 3 [R] COG5378 Predicted nucleotide-binding protein 1 1 3 3 ------------------------------------------------||--|------------- 3 [O] COG5380 Lipase chaperone 2 2 2 3 ------------------|-----------------------------------------|-|--- 3 [S] COG5381 Uncharacterized protein conserved in bacteria 2 3 3 3 -------------|||-------------------------------------------------- 3 [J] COG5384 U3 small nucleolar ribonucleoprotein component 1 1 1 3 ----------------------------------||-|---------------------------- 6 [M] COG5386 Cell surface protein 2 3 3 3 -------------|||-------------------------------------------------- 13 [UR] COG5391 Phox homology (PX) domain protein 1 1 3 3 ----------|||----------------------------------------------------- 3 [S] COG5399 Uncharacterized protein conserved in archaea 2 2 2 3 ---------------------|--------------------------------------|-|--- 3 [S] COG5403 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [KLB] COG5406 Nucleosome binding factor SPN, SPT16 subunit 2 3 3 3 -------------|||-------------------------------------------------- 3 [U] COG5407 Preprotein translocase subunit Sec63 2 3 3 3 -------------|||-------------------------------------------------- 8 [T] COG5408 SPX domain-containing protein 2 3 3 3 -------------|||-------------------------------------------------- 6 [T] COG5409 EXS domain-containing protein 2 3 3 3 -------------|||-------------------------------------------------- 8 [T] COG5411 Phosphatidylinositol 5-phosphate phosphatase 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5414 TATA-binding protein-associated factor 2 3 3 3 -------------|||-------------------------------------------------- 3 [R] COG5415 Predicted integral membrane metal-binding protein 2 2 2 3 -------------------|----------------------------------------|-|--- 4 [S] COG5420 Uncharacterized conserved small protein containing a coiled-coil domain 2 3 3 3 --|--|-------------|---------------------------------------------- 24 [L] COG5421 Transposase 2 3 3 3 -------------|||-------------------------------------------------- 5 [T] COG5422 RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases 1 2 2 3 ----------------------------------------------|------------|--|--- 4 [S] COG5426 Uncharacterized membrane protein 1 3 3 3 --||----|--------------------------------------------------------- 4 [S] COG5427 Uncharacterized membrane protein 2 2 3 3 --------|--||----------------------------------------------------- 3 [S] COG5431 Uncharacterized metal-binding protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [T] COG5432 RING-finger-containing E3 ubiquitin ligase 2 2 2 3 ------------------|-----------------------------------------|-|--- 3 [S] COG5439 Uncharacterized conserved protein 1 3 3 3 ---------------------------------------------|---------|--|------- 4 [S] COG5472 Predicted small integral membrane protein 1 1 1 3 -----------------------------------------------------------||-|--- 5 [S] COG5473 Predicted integral membrane protein 2 3 3 3 ------------------||----------------------------|----------------- 3 [S] COG5474 Uncharacterized conserved protein 2 2 3 3 --|-------|-|----------------------------------------------------- 3 [S] COG5483 Uncharacterized conserved protein 1 2 2 3 -------------------------------------------------------|----|-|--- 5 [S] COG5486 Predicted metal-binding integral membrane protein 1 1 2 3 ------------------------------------------------------------|-||-- 6 [S] COG5490 Uncharacterized conserved protein 1 1 3 3 ----------|||----------------------------------------------------- 5 [S] COG5493 Uncharacterized conserved protein containing a coiled-coil domain 1 1 3 3 ----------|||----------------------------------------------------- 3 [O] COG5494 Predicted thioredoxin/glutaredoxin 2 3 3 3 -------------||----------------------|---------------------------- 5 [M] COG5498 Predicted glycosyl hydrolase 2 2 2 3 -------------------|----------------------------------------|-|--- 3 [S] COG5500 Predicted integral membrane protein 2 3 3 3 ----------------|--------------------------------------|----|----- 3 [S] COG5501 Predicted secreted protein 3 3 3 3 --|---------------------------|------------------|---------------- 7 [S] COG5513 Predicted secreted protein 1 2 2 3 -------------------------------------------------------|-----||--- 3 [S] COG5514 Uncharacterized conserved protein 1 2 2 3 -------------------------------------------------------|----|-|--- 4 [R] COG5516 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding 2 2 3 3 -------------------|------------------------------------------||-- 3 [S] COG5526 Uncharacterized conserved protein 1 2 3 3 -------------------------------------------------|----------|--|-- 3 [S] COG5528 Predicted integral membrane protein 2 3 3 3 --|------------------------------------------|-----------------|-- 3 [R] COG5529 Pyocin large subunit 2 2 2 3 ---------------------|--------------------------------------|-|--- 3 [S] COG5530 Predicted integral membrane protein 1 2 3 3 ------------------------------------------|---------||------------ 3 [S] COG5532 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 4 [O] COG5533 Ubiquitin C-terminal hydrolase 2 3 3 3 ---------------------|---------------------------------|------|--- 4 [L] COG5534 Plasmid replication initiator protein 2 3 3 3 -------------|||-------------------------------------------------- 5 [L] COG5535 DNA repair protein RAD4 2 3 3 3 -------------|||-------------------------------------------------- 5 [O] COG5536 Protein prenyltransferase, alpha subunit 2 3 3 3 -------------|||-------------------------------------------------- 4 [D] COG5537 Cohesin 2 3 3 3 -------------|||-------------------------------------------------- 3 [U] COG5538 Preprotein translocase subunit Sec66 2 3 3 3 -------------|||-------------------------------------------------- 5 [O] COG5539 Predicted cysteine protease (OTU family) 2 3 3 3 -------------|||-------------------------------------------------- 4 [O] COG5540 RING-finger-containing ubiquitin ligase 2 3 3 3 -------------|||-------------------------------------------------- 3 [O] COG5541 Vesicle coat complex COPI, zeta subunit 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5543 Uncharacterized conserved protein 3 3 3 3 -------------------|-----------|--------------------|------------- 4 [R] COG5545 Predicted P-loop ATPase and inactivated derivatives 1 1 2 3 --------------------------------|-||------------------------------ 5 [S] COG5546 Small integral membrane protein 2 3 3 3 -------------||----|---------------------------------------------- 3 [S] COG5548 Small integral membrane protein 2 2 3 3 ----------||-------|---------------------------------------------- 10 [O] COG5550 Predicted aspartyl protease 2 2 2 3 ----------------------------|-------------------------------|-|--- 3 [S] COG5552 Uncharacterized conserved protein 2 3 3 3 -------------------|-----------------------------|------------|--- 3 [R] COG5553 Predicted metal-dependent enzyme of the double-stranded beta helix superfamily 2 2 2 3 -------------------|----------------------------------------|-|--- 3 [Q] COG5554 Nitrogen fixation protein 2 2 2 3 -------------------|----------------------------------------|-|--- 3 [N] COG5555 Cytolysin, a secreted calcineurin-like phosphatase 1 2 2 3 ---------------------------------------------|--------------|-|--- 4 [S] COG5556 Uncharacterized conserved protein 2 3 3 3 -----|--|--|------------------------------------------------------ 9 [L] COG5558 Transposase 2 3 3 3 -------||---------|----------------------------------------------- 4 [S] COG5559 Uncharacterized conserved small protein 2 3 3 3 -------------|||-------------------------------------------------- 4 [O] COG5560 Ubiquitin C-terminal hydrolase 1 3 3 3 -||-----|--------------------------------------------------------- 4 [S] COG5561 Predicted metal-binding protein 1 2 2 3 ---------------------------------------------|--------------|-|--- 6 [R] COG5564 Predicted TIM-barrel enzyme, possibly a dioxygenase 1 2 2 3 ----------------------------------------------------|-------|-|--- 5 [R] COG5565 Bacteriophage terminase large (ATPase) subunit and inactivated derivatives 1 2 3 3 -------------------------------------------------------|----|--|-- 3 [S] COG5572 Predicted integral membrane protein 2 3 3 3 -------------|||-------------------------------------------------- 6 [O] COG5574 RING-finger-containing E3 ubiquitin ligase 2 3 3 3 -------------|||-------------------------------------------------- 3 [L] COG5575 Origin recognition complex, subunit 2 2 3 3 3 -------------|||-------------------------------------------------- 14 [K] COG5576 Homeodomain-containing transcription factor 2 3 3 3 -------------|||-------------------------------------------------- 4 [O] COG5580 Activator of HSP90 ATPase 1 2 2 3 ----------------------------------------------------|--------||--- 3 [S] COG5587 Uncharacterized conserved protein 1 2 2 3 -------------------------------------------------------|----|-|--- 7 [S] COG5588 Uncharacterized conserved protein 1 2 3 3 ------------------------------------------------|-----------|--|-- 3 [S] COG5589 Uncharacterized conserved protein 1 3 3 3 ------------------------------------------------|------|-----|---- 4 [S] COG5591 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [J] COG5593 Nucleic-acid-binding protein possibly involved in ribosomal biogenesis 2 3 3 3 -------------|||-------------------------------------------------- 8 [S] COG5594 Uncharacterized integral membrane protein 2 3 3 3 -------------|||-------------------------------------------------- 7 [O] COG5596 Mitochondrial import inner membrane translocase, subunit TIM22 2 3 3 3 -------------||---------------------------------------------|----- 5 [M] COG5597 Alpha-N-acetylglucosamine transferase 2 2 2 3 --|---------------------------------------------------------|-|--- 13 [H] COG5598 Trimethylamine:corrinoid methyltransferase 2 3 3 3 -------------|||-------------------------------------------------- 6 [T] COG5599 Protein tyrosine phosphatase 2 3 3 3 -------------|||-------------------------------------------------- 5 [L] COG5600 Transcription-associated recombination protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5601 General negative regulator of transcription subunit 2 3 3 3 -------------|||-------------------------------------------------- 5 [B] COG5602 Histone deacetylase complex, SIN3 component 2 3 3 3 -------------|||-------------------------------------------------- 3 [N] COG5603 Subunit of TRAPP, an ER-Golgi tethering complex 2 3 3 3 -------------|||-------------------------------------------------- 4 [S] COG5604 Uncharacterized conserved protein 1 2 2 3 -------------------------------------------------------|----|-|--- 3 [S] COG5605 Predicted small integral membrane protein 1 2 2 3 ----------------------------------------------|----------||------- 3 [R] COG5610 Predicted hydrolase (HAD superfamily) 2 2 3 3 ----------------|-------------------------------------------|----| 3 [R] COG5611 Predicted nucleic-acid-binding protein, contains PIN domain 1 1 2 3 -----------------------------------------------------------|--||-- 3 [S] COG5612 Predicted integral membrane protein 1 2 2 3 ------------------------------------------------|-----------|-|--- 20 [S] COG5616 Predicted integral membrane protein 2 3 3 3 -------|-|--------------------|----------------------------------- 7 [S] COG5617 Predicted integral membrane protein 1 2 3 3 -------------------------------------------------|--|------|------ 3 [S] COG5619 Uncharacterized conserved protein 2 2 2 3 ------------------------------|----------------------------|--|--- 5 [S] COG5620 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [A] COG5623 Pre-mRNA cleavage and polyadenylation factor IA/II complex, subunit CLP1 2 3 3 3 -------------|||-------------------------------------------------- 3 [K] COG5624 Transcription initiation factor TFIID, subunit TAF12 (also component of histone acetyltransferase SAGA) 2 3 3 3 ------------------||-----------------------------|---------------- 3 [S] COG5626 Uncharacterized conserved small protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [L] COG5627 DNA repair protein MMS21 2 2 3 3 -------------------------------------|-------------------------|-| 3 [R] COG5628 Predicted acetyltransferase 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5629 Predicted metal-binding protein 2 3 3 3 -------------||-------------------------------------|------------- 3 [E] COG5630 Acetylglutamate synthase 1 2 2 3 -------------------------------------------------------|-----||--- 3 [K] COG5631 Predicted transcription regulator, contains HTH domain (MarR family) 1 1 1 3 ----------------------------------|||----------------------------- 12 [M] COG5632 N-acetylmuramoyl-L-alanine amidase 3 3 3 3 -------------------|----------------|------------------|---------- 3 [S] COG5634 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5636 Uncharacterized conserved protein, contains Zn-ribbon-like motif 2 3 3 3 ------------------||-|-------------------------------------------- 5 [S] COG5637 Predicted integral membrane protein 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5638 Uncharacterized conserved protein 1 2 3 3 -------------------------------------------------------|------||-- 5 [S] COG5639 Uncharacterized conserved small protein 1 2 2 3 ------------------------------------------------|-----------|-|--- 5 [O] COG5640 Secreted trypsin-like serine protease 2 3 3 3 -------------|||-------------------------------------------------- 13 [K] COG5641 GATA Zn-finger-containing transcription factor 1 2 2 3 ---------------------------------------------|--------------|-|--- 4 [S] COG5642 Uncharacterized conserved protein 1 3 3 3 |-|------|-------------------------------------------------------- 7 [R] COG5643 Protein containing a metal-binding domain shared with formylmethanofuran dehydrogenase subunit E 2 3 3 3 -------------|||-------------------------------------------------- 3 [S] COG5644 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 6 [O] COG5647 Cullin, a subunit of E3 ubiquitin ligase 2 3 3 3 -------------|||-------------------------------------------------- 10 [B] COG5648 Chromatin-associated proteins containing the HMG domain 1 2 2 3 -------------------------------------------------------|----|-|--- 5 [S] COG5649 Uncharacterized conserved protein 2 3 3 3 -------------|||-------------------------------------------------- 4 [O] COG5656 Importin, protein involved in nuclear import 2 3 3 3 -------------|||-------------------------------------------------- 7 [D] COG5657 CAS/CSE protein involved in chromosome segregation 2 3 3 3 ------------------|------------------------------------|------|--- 18 [L] COG5659 FOG: Transposase 2 3 3 3 -------------|||-------------------------------------------------- 4 [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit