y a o g gggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggg 4 6 9 14 -------------|-|--||----------------------|||||-||---|||---------- 16 [R] COG0429 Predicted hydrolase of the alpha/beta-hydrolase fold 4 10 11 14 -|-|--|||||-|-----||----------------------|---|------------|--|--- 14 [R] COG0434 Predicted TIM-barrel enzyme 4 10 12 14 |-|-||||||||||||-------------------------------------------------- 17 [J] COG1097 RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain) 4 6 8 14 ----------|-|-------------|||-----|-|-----|||-|--|-----|-----|---- 18 [C] COG1140 Nitrate reductase beta subunit 5 10 10 14 |||----|||-------|--|---------|-----------|||||------------------- 19 [C] COG1151 6Fe-6S prismane cluster-containing protein 4 7 9 14 -----------------|||----------|----||-----|||||-||-----|---------- 28 [KT] COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain 4 11 11 14 ||||||---|--------||------|||--------------------|-----|---------- 15 [H] COG1240 Mg-chelatase subunit ChlD 3 10 12 14 |||||||||||||--|-------------------------------------------------- 14 [J] COG1258 Predicted pseudouridylate synthase 4 11 12 14 |||||||||-||-||-------------------------------------------|------- 26 [R] COG1287 Uncharacterized membrane protein, required for N-linked glycosylation 4 8 9 14 ||-------|-------|--|---------||||||||-|-------------------------- 16 [R] COG1323 Predicted nucleotidyltransferase 6 12 13 14 |||--||-||||----||---------||--------|---------------------------- 18 [R] COG1353 Predicted hydrolase of the HD superfamily (permuted catalytic motifs) 5 8 9 14 ----------------||------||----|----|||----------||-----||||------- 14 [N] COG1419 Flagellar GTP-binding protein 3 4 6 14 -------------------------|----||||-|||----|||||-|----------------- 28 [G] COG1440 Phosphotransferase system cellobiose-specific component IIB 4 7 9 14 ----------------|-||-|--------------------|||||--|---|||-------|-- 16 [M] COG1462 Uncharacterized protein involved in formation of curli polymers 4 10 12 14 |-|||||||-||||||-------------------------------------------------- 41 [LO] COG1474 Cdc6-related protein, AAA superfamily ATPase 3 5 6 14 -----------------|------------|----|||----|||||-|----------||-|--- 37 [G] COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases 4 5 6 14 |--------------------|----||||||||||||---------------------------- 27 [S] COG1511 Predicted membrane protein 4 7 9 14 |-|-||-----|-||---------------------------|||||-|--|-------------- 18 [S] COG1584 Predicted membrane protein 4 10 12 14 |||-|||||||||---||------------------------------------------------ 14 [F] COG1618 Predicted nucleotide kinase 3 10 12 14 |||||||||||||--------|-------------------------------------------- 14 [S] COG1628 Uncharacterized conserved protein 6 9 9 14 |-|---||---|----||------------|-----||---------------------||||--- 25 [S] COG1633 Uncharacterized conserved protein 4 11 13 14 ||||--|||||||||--|------------------------------------------------ 14 [H] COG1635 Flavoprotein involved in thiazole biosynthesis 4 8 10 14 ||-|--||-||||------|------||||------------------------------------ 15 [L] COG1637 Predicted nuclease of the RecB family 4 11 13 14 ||||--||||||||||-------------------------------------------------- 15 [K] COG1675 Transcription initiation factor IIE, alpha subunit 4 11 13 14 ||||--||||||||||-------------------------------------------------- 14 [L] COG1697 DNA topoisomerase VI, subunit A 8 10 11 14 -------------|||||--||--|-----||--||||---------------------------- 16 [S] COG1774 Uncharacterized homolog of PSP1 3 10 12 14 |||-|||||||||||--------------------------------------------------- 14 [R] COG1779 C4-type Zn-finger protein 3 9 11 14 -||||||||||||-----------------------||---------------------------- 14 [S] COG1865 Uncharacterized conserved protein 6 11 12 14 |||-----||------||--|---------||---|------|||--------------------- 19 [I] COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) 4 11 13 14 ||||--||||||||||-------------------------------------------------- 18 [L] COG1948 ERCC4-type nuclease 3 9 11 14 |||-|||||||||--------------||------------------------------------- 16 [R] COG1964 Predicted Fe-S oxidoreductases 5 6 8 14 -----------------|-||---------|----|||----|||||-|--|-------------- 17 [C] COG1979 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family 7 8 9 14 ------||---|--------||-----||---|||-||-------|---------|---------- 17 [O] COG2039 Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) 8 11 13 14 -------||-|||||-|-||-|--------------||--------------------|------- 16 [P] COG2046 ATP sulfurylase (sulfate adenylyltransferase) 5 12 12 14 ||||----||---------|------|----|--------------------|--|---||-|--- 18 [R] COG2085 Predicted dinucleotide-binding enzymes 7 8 10 14 ----||--|-|||---|----|||-------------|------------------|||------- 14 [R] COG2107 Predicted periplasmic solute-binding protein 3 4 6 14 -----------------|-------------|----||----|||||---|--------||||--- 14 [G] COG2115 Xylose isomerase 4 10 12 14 |-|-||||||||||||-------------------------------------------------- 17 [J] COG2123 RNase PH-related exoribonuclease 5 8 10 14 ---|---------||----|--------------|-|-----|||-|--|-----|------||-- 16 [R] COG2130 Putative NADP-dependent oxidoreductases 5 6 9 14 --------------|---|-------|||--|-----|----|||-|-||-----------|---- 14 [R] COG2153 Predicted acyltransferase 3 5 6 14 -----------------|--|---------||||||||||||------------------------ 14 [L] COG2176 DNA polymerase III, alpha subunit (gram-positive type) 5 7 8 14 --------|-|---------------|||-----|-|-----|||-|--|-----|-----|---- 22 [C] COG2181 Nitrate reductase gamma subunit 3 6 9 14 -------------||---||----------------------|||||-||||----------|--- 52 [T] COG2198 FOG: HPt domain 3 10 12 14 |||||||||||||--|-------------------------------------------------- 15 [J] COG2263 Predicted RNA methylase 7 10 11 14 -||---------------||-|---|-||--|--|-||-----------|-----|---------- 24 [S] COG2314 Predicted membrane protein 5 6 8 14 ----||----|||--------|----|||||---|||----------------------------- 49 [R] COG2409 Predicted drug exporters of the RND superfamily 4 12 12 14 ||||||||||--||||-------------------------------------------------- 14 [U] COG2443 Preprotein translocase subunit Sss1 4 6 7 14 ---------------------|----||||||||-|||-----------|---------|------ 36 [TQ] COG2508 Regulator of polyketide synthase expression 5 5 7 14 ----------|-|--------|----|-----||||||---------------------||||--- 17 [R] COG2514 Predicted ring-cleavage extradiol dioxygenase 4 8 10 14 ----------------|-||----------|------------------|---|||--||||||-- 14 [R] COG2607 Predicted ATPase (AAA+ superfamily) 3 6 8 14 --------------------|---------|--|-----|--|||||-|-||----||-------- 29 [G] COG2731 Beta-galactosidase, beta subunit 5 8 10 14 --------------|---||-|-----||-------------------||-----|---|||||-- 14 [R] COG2802 Uncharacterized protein, similar to the N-terminal domain of Lon protease 4 8 10 14 ---------------------|----|---|--|-||-----|||-|--|-----|--|--|---- 20 [P] COG2807 Cyanate permease 3 5 8 14 -------------------------|-----------|----|||-|--|||------|||-||-- 14 [S] COG2861 Uncharacterized protein conserved in bacteria 3 5 6 14 --------------------|---||----|||||||||-||------------------------ 14 [J] COG2868 Predicted ribosomal protein 4 6 8 14 -----------------|------|-----|-----||----||||||||-----|---------- 14 [NUO] COG2882 Flagellar biosynthesis chaperone 1 2 7 14 ------------------------------------------||||||||||||||---------- 14 [KL] COG2901 Factor for inversion stimulation Fis, transcriptional activator 1 2 7 14 ------------------------------------------||||||||||||||---------- 14 [S] COG2914 Uncharacterized protein conserved in bacteria 1 2 7 14 ------------------------------------------||||||||||||||---------- 14 [S] COG2921 Uncharacterized conserved protein 1 2 7 14 ------------------------------------------||||||||||||||---------- 14 [CO] COG2924 Fe-S cluster protector protein 6 8 10 14 ---|---------------||-||-------------|-----------|--||||---||-|--- 14 [S] COG2928 Uncharacterized conserved protein 3 6 11 14 ----------------|-||-------------------------|--||--||||---||-||-- 70 [Q] COG2931 RTX toxins and related Ca2+-binding proteins 2 5 9 14 ---|----|----------------------------------------|--||||---||||||| 14 [R] COG2945 Predicted hydrolase of the alpha/beta superfamily 3 6 9 14 --------------------|-----------|---------|||||-||||---|--|-|----- 17 [S] COG2964 Uncharacterized protein conserved in bacteria 1 2 7 14 ------------------------------------------||||||||||||||---------- 14 [S] COG2976 Uncharacterized protein conserved in bacteria 2 3 5 14 --------------------------||||------------|||||-||---------|-||--- 14 [Q] COG2977 Phosphopantetheinyl transferase component of siderophore synthetase 2 3 6 14 ------------------|-----------------------|||||-||||-------||||--- 14 [E] COG2981 Uncharacterized protein involved in cysteine biosynthesis 3 7 9 14 --||||---------------------||-------------|-----|----|||---||-|--- 86 [L] COG3039 Transposase and inactivated derivatives, IS5 family 1 3 6 14 ------------------------------------------|||||-||---|||---||||--- 14 [S] COG3045 Uncharacterized protein conserved in bacteria 3 4 8 14 --------------------|-----------||--------|||||-|-|-|------||----| 16 [L] COG3077 DNA-damage-inducible protein J 3 5 8 14 ------------------|--|--------------------|||||--|--|--|---||-|--| 86 [NU] COG3121 P pilus assembly protein, chaperone PapD 2 5 9 14 ------------------||----------------------|||||-||--||||------|--- 15 [NU] COG3166 Tfp pilus assembly protein PilN 3 4 6 14 --------------------------|----|||--------|||||--|||----||-------- 15 [H] COG3201 Nicotinamide mononucleotide transporter 4 6 9 14 --------|---------|--------|||------------------||-----|---||-|||| 17 [I] COG3243 Poly(3-hydroxyalkanoate) synthetase 5 6 7 14 ---|||-----||--------|----||||----||||---------------------------- 14 [S] COG3253 Uncharacterized conserved protein 4 9 9 14 |||--|||-|-|---------------||-------------|||-|------------------- 20 [C] COG3260 Ni,Fe-hydrogenase III small subunit 6 7 9 14 ---|-------|-------|------|||--||--|-------|||------|--|---------- 16 [R] COG3378 Predicted ATPase 5 8 10 14 --|-|------|--|---------------|-----------|||||--|-|---|-------|-- 18 [S] COG3384 Uncharacterized conserved protein 6 8 9 14 --|--|-------------||-----|||----||--|-----------------|---||-|--- 98 [L] COG3464 Transposase and inactivated derivatives 4 6 9 14 -||---------------|-|---------------------|||||-||-|-------|--|--- 15 [L] COG3593 Predicted ATP-dependent endonuclease of the OLD family 5 7 8 14 ------||----------||------|||||||||----------------------------|-- 17 [K] COG3682 Predicted transcriptional regulator 5 5 8 14 --------------|------|----|||--|---|------|||||-||---------------- 14 [L] COG3695 Predicted methylated DNA-protein cysteine methyltransferase 5 8 10 14 -----------------|||-----|-----------|-----------|--------|||||||| 22 [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain 3 5 7 14 ---------------------|------------|-------|||||--|-|---|---||||--- 23 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 1 3 7 14 ------------------------------------------|||||-||--|--|---|||||-- 14 [T] COG3852 Signal transduction histidine kinase, nitrogen specific 3 5 8 14 ---------------------|-----||-------------|||||--|-|---|---|-|-|-- 16 [Q] COG3971 2-keto-4-pentenoate hydratase 2 3 6 14 ----------------------------------|-------|||||-||||-------||||--- 14 [P] COG4148 ABC-type molybdate transport system, ATPase component 1 4 6 14 ------------------------------------------|||||-||-----|||-||||--- 15 [R] COG4174 ABC-type uncharacterized transport system, permease component 1 2 6 14 ------------------------------------------|||||--||||------|||||-- 21 [O] COG4235 Cytochrome c biogenesis factor 1 2 7 14 ------------------------------------------||||||||||||||---------- 14 [P] COG4535 Putative Mg2+ and Co2+ transporter CorC 5 5 8 14 --|--------------|--|---|-----------------||||||||||-------------- 14 [C] COG4658 Predicted NADH:ubiquinone oxidoreductase, subunit RnfD 3 5 7 14 ---|----------------------||||-------------------|-----|---||||||| 24 [I] COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit 2 3 8 14 ----------------|-------------------------|||||-||||||||---------- 41 [NU] COG4969 Tfp pilus assembly protein, major pilin PilA 2 4 6 14 ------------------------------|--|||||----|||||-|----------|--|--- 14 [R] COG4989 Predicted oxidoreductase 1 2 7 14 ------------------------------------------||||||||||||||---------- 14 [K] COG5007 Predicted transcriptional regulator, BolA superfamily 4 6 8 14 ----------|-|-------------|||-----|-|-----|||-|--|-----|-----|---- 21 [C] COG5013 Nitrate reductase alpha subunit