y a o g gggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggg 4 12 13 13 ||||----||--------||----------|----|----------|---|----------|---- 24 [P] COG0310 ABC-type Co2+ transport system, permease component 5 8 8 13 --|-----||------|--|----------|-----------|||-|---------|||------- 21 [C] COG0374 Ni,Fe-hydrogenase I large subunit 4 10 12 13 -|||--||||||||||-------------------------------------------------- 14 [T] COG0478 RIO-like serine/threonine protein kinase fused to N-terminal HTH domain 5 8 8 13 |--------------------|----|||||---------|||---|-----------||------ 13 [M] COG0562 UDP-galactopyranose mutase 3 11 11 13 |||||||||||--||--------------------------------------------------- 13 [R] COG1019 Predicted nucleotidyltransferase 5 11 11 13 -|||--||||-------|------||-----------|-----------|--------|------- 19 [R] COG1033 Predicted exporters of the RND superfamily 3 4 5 13 ----------------|-----||-------||||||-||||------------------------ 13 [L] COG1039 Ribonuclease HIII 3 4 4 13 -------------|--------------------|-||----|||||------------||||--- 17 [C] COG1069 Ribulose kinase 3 9 11 13 |-|-|||||||||||--------------------------------------------------- 13 [J] COG1096 Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain) 4 6 8 13 --------------------|-----|-----||--------------||-----|---||||-|| 13 [R] COG1101 ABC-type uncharacterized transport system, ATPase component 4 10 11 13 -||||||||-|-|||--|------------------------------------------------ 20 [J] COG1184 Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family 4 11 12 13 ||||--||||-|||||-------------------------------------------------- 31 [O] COG1222 ATP-dependent 26S proteasome regulatory subunit 6 7 7 13 ----||||---|----------|||-||||-------------------------|---------- 13 [C] COG1274 Phosphoenolpyruvate carboxykinase (GTP) 4 6 6 13 ----------------|----|-------------|||----|||||--------|----|-|--- 13 [P] COG1276 Putative copper export protein 4 5 7 13 --------------------|----|------|||-||----|||-|---|------------|-- 19 [S] COG1288 Predicted membrane protein 4 8 11 13 ---|--|------|-------------||--------------------||-||||--|----|-- 14 [S] COG1297 Predicted membrane protein 5 6 7 13 -----------------|--||||------||||||||---------------------------- 29 [S] COG1302 Uncharacterized protein conserved in bacteria 3 11 11 13 ||||||||||---|||-------------------------------------------------- 13 [L] COG1311 Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B 2 9 11 13 |||||||||||||----------------------------------------------------- 13 [KH] COG1339 Transcriptional regulator of a riboflavin/FAD biosynthetic operon 2 9 11 13 |||||||||||||----------------------------------------------------- 13 [O] COG1370 Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit 2 9 11 13 |||||||||||||----------------------------------------------------- 13 [K] COG1395 Predicted transcriptional regulator 6 10 10 13 -||-----|-------|--|-|--------|--|--------|||-|---------------|--- 15 [O] COG1397 ADP-ribosylglycohydrolase 7 8 9 13 ----||--|-|-|---|----|||-------------|------------------|||------- 13 [R] COG1427 Predicted periplasmic solute-binding protein 5 11 11 13 |||-|||||||------|------------|-----------------|----------------- 28 [S] COG1433 Uncharacterized conserved protein 2 4 7 13 ---------------------------------|--|-----|||-|---||----||--|---|| 30 [M] COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases 2 9 11 13 |||||||||||||----------------------------------------------------- 13 [S] COG1460 DNA-directed RNA polymerase, subunit F 2 9 11 13 |||||||||||||----------------------------------------------------- 13 [J] COG1491 Predicted RNA-binding protein 5 6 8 13 ------||-----------|-|----|||------------------------||-------|||| 17 [E] COG1505 Serine proteases of the peptidase family S9A 7 10 12 13 |-|-----|--|-------|||---------------|----|--|--|---|--|---------- 23 [H] COG1541 Coenzyme F390 synthetase 6 8 10 13 ---|||----|||---|-||-|------------|-||---------------------------- 13 [S] COG1547 Uncharacterized conserved protein 2 9 11 13 |||||||||||||----------------------------------------------------- 17 [R] COG1571 Predicted DNA-binding protein containing a Zn-ribbon domain 7 7 7 13 ----------------|----|||||||-||-------------------------|||------- 13 [R] COG1579 Zn-ribbon protein, possibly nucleic acid-binding 7 13 13 13 |||----|||-|-----|-||---------|-----|---------------------|------- 28 [C] COG1592 Rubrerythrin 2 9 11 13 |||||||||||||----------------------------------------------------- 13 [R] COG1608 Predicted archaeal kinase 2 9 11 13 |||||||||||||----------------------------------------------------- 13 [R] COG1634 Uncharacterized Rossmann fold enzyme 6 11 12 13 |||---||--||-----||||------------------------|------------|------- 91 [R] COG1672 Predicted ATPase (AAA+ superfamily) 3 9 10 13 |||---|||||-|------------------------------------|---------||-|--- 13 [S] COG1679 Uncharacterized conserved protein 2 9 11 13 |||||||||||||----------------------------------------------------- 13 [J] COG1746 tRNA nucleotidyltransferase (CCA-adding enzyme) 4 9 11 13 -|--||||||||||||-------------------------------------------------- 13 [S] COG1756 Uncharacterized conserved protein 2 9 11 13 |||||||||||||----------------------------------------------------- 14 [R] COG1782 Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain 3 9 10 13 |||---|||||-|------------------------------------|---------||-|--- 13 [S] COG1786 Uncharacterized conserved protein 4 11 11 13 |||||||||-|-------||-----------------|---------------------------- 13 [S] COG1836 Predicted membrane protein 5 8 10 13 |---|||||-|||----|---------||--------------------------|---------- 13 [S] COG1839 Uncharacterized conserved protein 2 9 11 13 |||||||||||||----------------------------------------------------- 13 [S] COG1849 Uncharacterized protein conserved in archaea 2 9 11 13 |||||||||||||----------------------------------------------------- 13 [R] COG1855 ATPase (PilT family) 6 10 11 13 --|----------||----||----|--------------------|--|-----||||----|-- 15 [F] COG1864 DNA/RNA endonuclease G, NUC1 2 10 10 13 ||||||||||--------------------|-----||---------------------------- 25 [S] COG1873 Uncharacterized conserved protein 5 6 8 13 -----------------|----||--||||------||----------||--|--|---------- 14 [T] COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH 4 10 12 13 |||---||||||||||-------------------------------------------------- 14 [J] COG1911 Ribosomal protein L30E 2 9 11 13 |||||||||||||----------------------------------------------------- 17 [R] COG1938 Archaeal enzymes of ATP-grasp superfamily 3 5 7 13 --------------------|-------------|-||----------||||-||-|||------- 15 [R] COG2056 Predicted permease 2 9 11 13 |||||||||||||----------------------------------------------------- 13 [K] COG2093 DNA-directed RNA polymerase, subunit E'' 4 10 12 13 |||---||||||||||-------------------------------------------------- 16 [JA] COG2136 Predicted exosome subunit/U3 small nucleolar ribonucleoprotein (snoRNP) component, contains IMP4 domain 4 10 12 13 |||---||||||||||-------------------------------------------------- 15 [J] COG2157 Ribosomal protein L20A (L18A) 5 10 12 13 ||----||-|||||||--------------|------|---------------------------- 22 [J] COG2163 Ribosomal protein L14E/L6E/L27E 6 8 8 13 -----------------|||-|||---||-|---||||---------------------------- 28 [T] COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase) 3 6 8 13 -------------||------------|||------------||||--||-----|------|--- 24 [Q] COG2175 Probable taurine catabolism dioxygenase 7 10 11 13 ----------------||-|-|--||----|------|----------||-----|---|--|--- 35 [T] COG2206 HD-GYP domain 6 9 9 13 |||-||-----|----||----------------||--------------------|||------- 13 [L] COG2231 Uncharacterized protein related to Endonuclease III 2 9 11 13 |||||||||||||----------------------------------------------------- 13 [H] COG2266 GTP:adenosylcobinamide-phosphate guanylyltransferase 5 7 8 13 -------------------|||--------||-|--||----|||-|-------------|----- 30 [S] COG2323 Predicted membrane protein 3 5 8 13 ---------------------|----|||-------------|||-|-||---|-------|-|-- 13 [S] COG2354 Uncharacterized protein conserved in bacteria 4 5 6 13 --------------------||----|||-||||||||---------------------------- 21 [S] COG2357 Uncharacterized protein conserved in bacteria 6 8 11 13 ---|----|---|-----|--|---------------|----------||-|--------||--|| 21 [R] COG2358 TRAP-type uncharacterized transport system, periplasmic component 5 9 12 13 ----||--|-|||-----||-|---------------------------|-----|-----|-|-- 20 [R] COG2366 Protein related to penicillin acylase 4 6 6 13 ---------------------|----|--------|||----|||||--------|----|-|--- 13 [R] COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC 3 5 7 13 ---------------------|----|||-------------|||-|-||-----|---||----- 21 [P] COG2375 Siderophore-interacting protein 3 5 6 13 ---------------------|--------|||||||||-||------|----------------- 13 [R] COG2384 Predicted SAM-dependent methyltransferase 5 6 8 13 ------||--|-|----|------------|--|--------|||||---|--------------- 15 [G] COG2407 L-fucose isomerase and related proteins 4 8 9 13 -||-|||||-|-|-----------------|-----------|||--------------------- 33 [C] COG2414 Aldehyde:ferredoxin oxidoreductase 5 6 8 13 ----||----|||----|--|---------------------|||-|-------------|-|--- 21 [C] COG2440 Ferredoxin-like protein 2 9 11 13 |||||||||||||----------------------------------------------------- 13 [J] COG2511 Archaeal Glu-tRNAGln amidotransferase subunit E (contains GAD domain) 2 4 5 13 ------------------------------|----|||----|||||---||-||----------- 13 [S] COG2707 Predicted membrane protein 3 5 7 13 ---|--------------------------|-----||----|||||-||----------|-|--- 13 [S] COG2718 Uncharacterized conserved protein 3 5 7 13 ---|--------------------------|-----||----|||||-||----------|-|--- 13 [S] COG2719 Uncharacterized conserved protein 4 6 8 13 ----------------||------------|-----||----|||||-||-----|---------- 13 [KNU] COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor) 3 5 7 13 ---|--------------------------|-----||----|||||-||----------|-|--- 14 [T] COG2766 Putative Ser protein kinase 6 10 11 13 --|-----|-------|-||-|--------------|-----------||-----|---||-|--- 23 [T] COG2770 FOG: HAMP domain 2 4 8 13 ------------------------------------|-----|||---||--||||---||-|--- 13 [S] COG2828 Uncharacterized protein conserved in bacteria 5 6 8 13 --|------------------|-----||---||-||----------------||-----|-||-- 15 [M] COG2843 Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) 5 8 11 13 -||------||||-------------|---||-|-|-----------------||----------- 14 [S] COG2848 Uncharacterized conserved protein 2 3 7 13 ------------------------------------|-----|||||--|||||||---------- 14 [S] COG2850 Uncharacterized conserved protein 2 9 11 13 |||||||||||||----------------------------------------------------- 13 [J] COG2888 Predicted Zn-ribbon RNA-binding protein with a function in translation 1 3 7 13 ------------------------------------------|||||-|||||--|--------|| 14 [S] COG2904 Uncharacterized protein conserved in bacteria 3 5 9 13 ------------------|---------|-------------||-||-||--||||-------|-- 13 [P] COG2906 Bacterioferritin-associated ferredoxin 3 4 7 13 |-|--------------|------------------------||||||||||-------------- 13 [P] COG2923 Uncharacterized protein involved in the oxidation of intracellular sulfur 2 2 6 13 ---------------------------|||------------|||||-|||||------------- 15 [I] COG2937 Glycerol-3-phosphate O-acyltransferase 2 5 7 13 ------------------||----------------------|||-|-----|--|---|||||-- 16 [G] COG2942 N-acyl-D-glucosamine 2-epimerase 2 4 8 13 -------------------|----------------------|||-|-|---||||---||----| 20 [K] COG2944 Predicted transcriptional regulator 1 2 7 13 ------------------------------------------|||||-||||||||---------- 13 [R] COG2969 Stringent starvation protein B 1 2 7 13 ------------------------------------------|||||-||||||||---------- 13 [L] COG2974 DNA recombination-dependent growth factor C 4 6 8 13 --------------------|-----|-------|--|----||||--|--|-||--------|-- 19 [H] COG2978 Putative p-aminobenzoyl-glutamate transporter 1 3 6 13 ------------------------------------------|||-|-||-|-||----||||--- 13 [S] COG2979 Uncharacterized protein conserved in bacteria 1 2 7 13 ------------------------------------------|||||-||||||||---------- 13 [M] COG2980 Rare lipoprotein B 1 2 5 13 ------------------------------------------|||||-|-||-------|||||-- 17 [S] COG2989 Uncharacterized protein conserved in bacteria 1 4 7 13 ------------------------------------------------||---|||||||||||-- 18 [C] COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit 4 8 10 13 -------------||---||-------||-------------------||-----|---||-||-- 32 [I] COG3000 Sterol desaturase 3 4 8 13 ---------------------|----|---------------|||||-||||-|-|---------- 13 [S] COG3012 Uncharacterized protein conserved in bacteria 1 2 7 13 ------------------------------------------|||||-||||||||---------- 13 [M] COG3017 Outer membrane lipoprotein involved in outer membrane biogenesis 3 4 7 13 -------------------|-|--------------------|||||-|--|-------|-|||-- 14 [S] COG3021 Uncharacterized protein conserved in bacteria 2 4 8 13 --|---------------------------------------|||||-||||---|------||-- 14 [S] COG3025 Uncharacterized conserved protein 1 2 7 13 ------------------------------------------|||||-||||||||---------- 13 [S] COG3028 Uncharacterized protein conserved in bacteria 1 2 7 13 ------------------------------------------|||||-||||||||---------- 13 [H] COG3071 Uncharacterized enzyme of heme biosynthesis 1 2 7 13 ------------------------------------------|||||-||||||||---------- 13 [D] COG3087 Cell division protein 4 5 9 13 --------------------|-----|----------|----|--||-||||-------||--|-- 43 [G] COG3090 TRAP-type C4-dicarboxylate transport system, small permease component 4 5 10 13 -------------------||-----|---------------|||---|||-|-------|-||-- 21 [R] COG3093 Plasmid maintenance system antidote protein 1 2 5 13 ------------------------------------------|||||-|-||-------|||||-- 19 [S] COG3108 Uncharacterized protein conserved in bacteria 1 2 7 13 ------------------------------------------|||||-||||||||---------- 15 [S] COG3117 Uncharacterized protein conserved in bacteria 1 3 6 13 ------------------------------------------|||||-||-----|---|||||-- 13 [Q] COG3127 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component 3 5 7 13 -----------------|------------|-----||----||||||||-----|---------- 14 [N] COG3144 Flagellar hook-length control protein 2 3 7 13 -------------------------------|--||------|||||-||----------|-||-- 30 [S] COG3152 Predicted membrane protein 3 4 6 13 ----------------------||------------||----||||||||-----|---------- 13 [N] COG3190 Flagellar biogenesis protein 2 4 5 13 --------------------------||||-------------------|------||||||||-- 15 [E] COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase 4 6 9 13 --|-----------------|-----------|-||||----------||---||-------||-- 18 [S] COG3212 Predicted membrane protein 3 4 7 13 ---|---------------|----------------------|||||-||---------||-||-- 13 [R] COG3217 Uncharacterized Fe-S protein 4 5 7 13 -----------|-----|-------------|||---|----||||------|------||----- 24 [G] COG3250 Beta-galactosidase/beta-glucuronidase 4 9 9 13 |||--|||-|-|---------------|--------------|||-|------------------- 19 [C] COG3261 Ni,Fe-hydrogenase III large subunit 1 4 7 13 ------------------------------------------------||---|||||||||||-- 20 [O] COG3278 Cbb3-type cytochrome oxidase, subunit 1 3 6 9 13 -------------------|----------|-----||----|-----||-----|---|||||-- 16 [QK] COG3284 Transcriptional activator of acetoin/glycerol metabolism 3 6 8 13 --|----------------------------|||-|||--------|--|---||-|--|------ 13 [S] COG3326 Predicted membrane protein 4 8 9 13 |-|---------------||----------|-----||-----------------|---|||||-- 15 [S] COG3339 Uncharacterized conserved protein 6 6 7 13 -------------------|||----|--------|||----|||-|---||-------------- 14 [E] COG3340 Peptidase E 4 7 11 13 ---------||||-----------------|||---||--------|--|-----|------|--- 13 [S] COG3382 Uncharacterized conserved protein 4 6 7 13 ------------------|||----------------|----|--||---||-------||||--- 18 [S] COG3395 Uncharacterized protein conserved in bacteria 6 8 9 13 ---|||-----|-|||---------|-----|||||------------------------------ 17 [I] COG3407 Mevalonate pyrophosphate decarboxylase 2 4 7 13 --|---------------------------------------||||---|-|-||----|-|||-- 15 [S] COG3422 Uncharacterized conserved protein 5 7 9 13 ---|||----|||--------|-----||--------------------------|----|||--- 14 [S] COG3427 Uncharacterized conserved protein 4 7 7 13 --||-|---------------|----------||---------|||-------------||||--- 109 [L] COG3436 Transposase and inactivated derivatives 3 4 6 13 --------------------|---------||||-||-----|||||----|-------------- 34 [G] COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB 1 3 4 13 ------------------------------------------|||||---||-||----||||--- 55 [MU] COG3468 Type V secretory pathway, adhesin AidA 3 5 9 13 --------------------|-----|---------------|||---|-|--|-|---||-||-- 17 [R] COG3550 Uncharacterized protein related to capsule biosynthesis enzymes 4 7 8 13 -------------||-----|-----|||--------------------|-----|---|||||-- 21 [E] COG3616 Predicted amino acid aldolase or racemase 2 4 6 13 --------------------------|---------------|||||--|||---|----|||--- 21 [G] COG3622 Hydroxypyruvate isomerase 2 4 7 13 --------------------------------|---------|||||-||||-||---|------- 13 [E] COG3633 Na+/serine symporter 4 7 9 13 --|-----------|------|--------------------|||-|----|-|||--|----|-- 13 [L] COG3663 G:T/U mismatch-specific DNA glycosylase 5 8 8 13 --||--||---|------|-----------|-----------|||||--------|---------- 51 [L] COG3677 Transposase and inactivated derivatives 3 7 9 13 ----------------|-||----------------------|||-|--|-----|||--|--|-- 23 [P] COG3696 Putative silver efflux pump 2 4 7 13 --------------------|---------------------|||||-|--|---|---||-||-- 20 [M] COG3713 Outer membrane protein V 3 4 6 13 --------------------|---------||||-||-----|||||----|-------------- 33 [G] COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC 3 4 6 13 --------------------|---------||||-||-----|||||----|-------------- 34 [G] COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID 3 4 6 13 ------------------------|-----|-----------|||||-|----------|||||-- 13 [S] COG3735 Uncharacterized protein conserved in bacteria 4 6 8 13 --------------------|-----|-----||--------------||-----|---||||-|| 13 [R] COG4120 ABC-type uncharacterized transport system, permease component 2 4 6 13 --------------------|---------------------|||||-||-----|---||||--- 23 [R] COG4172 ABC-type uncharacterized transport system, duplicated ATPase component 4 9 11 13 |-|-|||||-||------------------|------------------------|------||-- 20 [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits 4 6 6 13 --|------------------------||-----||-|-----|||---------|---||-|--- 97 [L] COG4584 Transposase and inactivated derivatives 4 4 7 13 --|--------------|--|---------------------||||||||||-------------- 13 [C] COG4657 Predicted NADH:ubiquinone oxidoreductase, subunit RnfA 4 4 7 13 --|--------------|--|---------------------||||||||||-------------- 13 [C] COG4659 Predicted NADH:ubiquinone oxidoreductase, subunit RnfG 4 4 7 13 --|--------------|--|---------------------||||||||||-------------- 13 [C] COG4660 Predicted NADH:ubiquinone oxidoreductase, subunit RnfE 3 4 8 13 -------------------||---------------------|||-|----||------||-||-| 13 [M] COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC 1 2 7 13 ------------------------------------------|||||-||||||||---------- 13 [L] COG4973 Site-specific recombinase XerC