Functional categories
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88 COGs Q Secondary metabolites biosynthesis, transport and catabolism
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 9 19 24 31 ||||-||||||||||-|||-----|--|--|-||-||-  55 [BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein
 8 15 18 23 -||-|-|||||||-|-||----|-|---------|||-  49 [EQ] COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit
 7 13 16 20 -||-|--||||||-|-||----|-----------|||-  29 [EQ] COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit
 8 20 27 43 |||||||||||||---|||---|-|--||-|||||||-  78 [Q]  COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
12 19 27 53 --|--------||-|||||||||||||||||||||||| 115 [IQ] COG0236 Acyl carrier protein
10 16 24 46 -----------||-|||||||-||||-||||||||||| 105 [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase
 9 18 28 47 |-|||-|-|||||---|||-|-|-||-||||||||||| 257 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II
 8 13 15 23 --|-|----|-||-|-||----|-|--||---|--||-  50 [Q]  COG0412 Dienelactone hydrolase and related enzymes
14 27 37 61 ||||||||||||||||||||||||||-||||||||||| 786 [QR] COG0500 SAM-dependent methyltransferases
 4  8 15 29 --------------|-||----|----|||||||||||  49 [Q]  COG0767 ABC-type transport system involved in resistance to organic solvents, permease component
 5  9 12 25 -----------||---|-----|-||-||-|-|-|-|- 145 [Q]  COG1020 Non-ribosomal peptide synthetase modules and related proteins
 3  4  6 11 ----------------------|-|--||-|-----|-  11 [Q]  COG1021 Peptide arylation enzymes
13 23 33 57 --|||||-|||||||||||||-||||-||||||||||| 825 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
 4  8 15 29 --------------|-||----|----|||||||||||  35 [Q]  COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component
 5  7 11 21 ---|------------||----|-||-||-||----|-  27 [HQ] COG1169 Isochorismate synthase
 9 16 20 28 |--||||--|-|---|--||--||||-||-|-|--||-  45 [Q]  COG1228 Imidazolonepropionase and related amidohydrolases
 7 12 14 18 ||||-----||-----|||---|-|-------|--||-  53 [Q]  COG1233 Phytoene dehydrogenase and related proteins
11 21 29 47 --|||||||||||-|||-|--|||||-||||-|||||- 126 [Q]  COG1335 Amidases related to nicotinamidase
 4  8 15 29 --------------|-||----|----|||||||||||  87 [Q]  COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component
 3  4  6  9 ---------------|--------|--||-|-----|-  10 [Q]  COG1535 Isochorismate hydrolase
 3  4  6  9 -----------|----------|----||-|----|--   9 [Q]  COG2015 Alkyl sulfatase and related hydrolases
 8 15 21 40 --|||||-||--|-|---|---|-||-||-|||-|||-  88 [Q]  COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism
 7 13 15 22 ---|-------||---|||---|||--|-|--|-|||-  98 [Q]  COG2124 Cytochrome P450
 8 12 17 29 ---|----|--||-|-|-----|-|--|||-||||||-  54 [Q]  COG2132 Putative multicopper oxidases
 3  4  6 12 ----------------------|-|--||------||-  14 [Q]  COG2162 Arylamine N-acetyltransferase
 3  6  8 13 -----------||---------|----||-|-|---|-  24 [Q]  COG2175 Probable taurine catabolism dioxygenase
 5  6  6 11 ------------|--|--|-----|---|-------|-  11 [Q]  COG2313 Uncharacterized enzyme involved in pigment biosynthesis
 5  5  8 10 ------|-||--------|-----|--||--|------  15 [Q]  COG2368 Aromatic ring hydroxylase
 4  6  7 14 ------------------|---||||-|--------|-  36 [TQ] COG2508 Regulator of polyketide synthase expression
 6  9 11 17 ---|-----|--------|---|||----||-|--||-  20 [Q]  COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis
 1  4 10 17 ---------------------------|||||||||-|  17 [Q]  COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component
 3  6 11 14 --------------|-||---------||||-||-||-  70 [Q]  COG2931 RTX toxins and related Ca2+-binding proteins
 2  3  5 14 ----------------------|----||-|-----|-  14 [Q]  COG2977 Phosphopantetheinyl transferase component of siderophore synthetase
 1  3  6 13 ---------------------------||-|-|--||-  13 [Q]  COG3127 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component
 3  4  6 11 ------------------|---|----||-|-----|-  12 [Q]  COG3135 Uncharacterized protein involved in benzoate metabolism
 1  1  3  7 ---------------------------||-|-------   7 [Q]  COG3155 Uncharacterized protein involved in an early stage of isoprenoid biosynthesis
 5  7  8 15 -----|---|--------|---|----|----|--||-  21 [EQ] COG3191 L-aminopeptidase/D-esterase
 2  2  3  3 -----------|---------------|--|-------   3 [Q]  COG3207 Pyoverdine/dityrosine biosynthesis protein
 4  7  8 12 ----------------|-----|||--||---|---|-  19 [Q]  COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis
 3  6  9 13 ----------------|------||--||-|-|--||-  16 [QK] COG3284 Transcriptional activator of acetoin/glycerol metabolism
 6  7  9 12 --|-------------|--|--|-|--|--||----|-  55 [Q]  COG3315 O-Methyltransferase involved in polyketide biosynthesis
 4  6  7 15 ----------------|-----|-|--||---|---|-  24 [Q]  COG3319 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases
 5  7  7  9 -----------||---|-----|-|--|--------|-  15 [Q]  COG3320 Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes
 4  7  7 12 ----------------|-----|||---|---|---|-  90 [Q]  COG3321 Polyketide synthase modules and related proteins
 3  3  3  5 ------------------|---|-|-------------  10 [Q]  COG3424 Predicted naringenin-chalcone synthase
 3  4  6 11 ----------------------|-|--||-|-----|-  11 [Q]  COG3433 Aryl carrier domain
 4  5  6  8 ---------|------------|-|--||---|-----  10 [Q]  COG3435 Gentisate 1,2-dioxygenase
 3  3  4  6 ---------------|--------||----------|-   7 [Q]  COG3458 Acetyl esterase (deacetylase)
 3  5  5  5 ------------------|-----|---|---|---|-   5 [Q]  COG3460 Uncharacterized enzyme of phenylacetate metabolism
 3  4  5  7 -----|---||---------------------|---|-   8 [Q]  COG3473 Maleate cis-trans isomerase
 2  2  3  3 ------------------------||----|-------   3 [Q]  COG3479 Phenolic acid decarboxylase
 2  4  7 11 ----------------------|----||---|--|||  26 [Q]  COG3485 Protocatechuate 3,4-dioxygenase beta subunit
 5  7  8  9 ---|--------|---|-------|--||---|---|-  11 [Q]  COG3486 Lysine/ornithine N-monooxygenase
 2  4  6  7 ---------|-----------------|--|-|--||-   7 [Q]  COG3508 Homogentisate 1,2-dioxygenase
 2  4  5 10 ----------------------|----|----|--||-  12 [Q]  COG3509 Poly(3-hydroxybutyrate) depolymerase
 3  4  5  8 --|--------------------|||----|-------  11 [Q]  COG3527 Alpha-acetolactate decarboxylase
 3  3  3  4 ------------|-----|-----|-------------   4 [Q]  COG3648 Uricase (urate oxidase)
 3  4  4  5 -----|----------------|---------|--|--   5 [Q]  COG3653 N-acyl-D-aspartate/D-glutamate deacylase
 3  5  5  6 ----------------||----|---------|--|--  12 [Q]  COG3670 Lignostilbene-alpha,beta-dioxygenase and related enzymes
 5  6  6  6 ---------|--|---|-|---------|-------|-   6 [Q]  COG3733 Cu2+-containing amine oxidase
 2  3  3  3 ----------------|-------------|-----|-   3 [Q]  COG3805 Aromatic ring-cleaving dioxygenase
 2  4  4  4 -----------------------||---------|-|-   7 [Q]  COG3882 Predicted enzyme involved in methoxymalonyl-ACP biosynthesis
 1  3  4  6 ---------------------------||---|---|-  12 [TQ] COG3916 N-acyl-L-homoserine lactone synthetase
 1  3  4  4 ---------------------------|----|--||-   5 [Q]  COG3917 2-hydroxychromene-2-carboxylate isomerase
 3  5  8 14 ------------------|---|----||--||--||-  16 [Q]  COG3971 2-keto-4-pentenoate hydratase
 1  3  6 12 ---------------------------||-|-|--||-  12 [Q]  COG4181 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component
 2  3  3  3 ----------------||-----------------|--   5 [QP] COG4242 Cyanophycinase and related exopeptidases
 4  6  6  7 ---|------------|-------|---|---|---|-  19 [Q]  COG4264 Siderophore synthetase component
 2  3  3  4 ----------------------|---------|--|--   5 [Q]  COG4308 Limonene-1,2-epoxide hydrolase
 2  4  4  4 -----------------------||---|-------|-   5 [Q]  COG4542 Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase
 2  3  3  6 ----------------------|-----|---|-----   6 [Q]  COG4569 Acetaldehyde dehydrogenase (acetylating)
 4  5  5  8 ----------------||-|----|---|---------  10 [QC] COG4576 Carbon dioxide concentrating mechanism/carboxysome shell protein
 4  5  5  8 ----------------||-|----|---|---------  31 [QC] COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein
 1  3  4  7 ---------------------------||---|-|---   7 [QP] COG4615 ABC-type siderophore export system, fused ATPase and permease components
 1  2  2  4 ----------------------------------|-|-   4 [Q]  COG4647 Acetone carboxylase, gamma subunit
 2  4  4  7 ----------------||------------|-----|-  11 [Q]  COG4663 TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component
 2  4  4  7 ----------------||------------|-----|-   9 [Q]  COG4664 TRAP-type mannitol/chloroaromatic compound transport system, large permease component
 2  4  4  7 ----------------||------------|-----|-   9 [Q]  COG4665 TRAP-type mannitol/chloroaromatic compound transport system, small permease component
 2  3  3  3 -----------------------|--------|---|-   5 [Q]  COG4689 Acetoacetate decarboxylase
 1  2  3  3 ---------------------------||---|-----   4 [Q]  COG4693 Oxidoreductase (NAD-binding), involved in siderophore biosynthesis
 2  2  2  4 ----------------------|----|----------   4 [Q]  COG4829 Muconolactone delta-isomerase
 3  3  3  3 ---------------|--------|---|---------   4 [Q]  COG4869 Propanediol utilization protein
 2  3  3  3 ------------------------|---|-------|-   3 [Q]  COG4909 Propanediol dehydratase, large subunit
 2  3  3  3 ------------------------|---|-------|-   3 [Q]  COG4910 Propanediol dehydratase, small subunit
 4  5  5  7 -----------|----|-----|---------|---|-   9 [Q]  COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin
 2  2  2  5 --|---------------------------------|-   6 [Q]  COG5310 Homospermidine synthase
 2  3  4  6 ----------------------|----||---|-----   8 [Q]  COG5517 Small subunit of phenylpropionate dioxygenase
 2  2  2  3 ----------------|-------------------|-   3 [Q]  COG5554 Nitrogen fixation protein