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11 22 30 48 |||||-|||||-|-|-|||||-|||--||||||||||- 61 [H] COG0001 Glutamate-1-semialdehyde aminotransferase
10 21 28 44 |||||-|||||||-|-||||--|||--||||-||-||- 67 [H] COG0007 Uroporphyrinogen-III methylase
10 22 31 49 |||-|||||||||-|||||---||||-||||||||||- 146 [EH] COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]
8 13 18 30 ---|-|---|----|-||-|--|||--||||-||-||- 32 [H] COG0029 Aspartate oxidase
9 19 27 41 |||-||||||||--|-|||-|---|--||-|||||||| 51 [H] COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases
12 23 32 51 ||||--|||||||-|||||||-||||-||||||||||- 55 [H] COG0054 Riboflavin synthase beta-chain
10 20 28 47 |||--|||||-|--|||||---||||-||||||||||- 49 [EH] COG0059 Ketol-acid reductoisomerase
10 15 19 33 ---|||---||||-||||--|-|-|||||-|------- 61 [H] COG0095 Lipoate-protein ligase A
12 23 32 51 ||||--|||||||-|||||||-||||-||||||||||- 57 [H] COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase
10 23 31 49 |||||||||||||-|||||---||||-||||||-|||- 113 [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases
11 23 32 51 |||||-|||||||-|-|||||-|||--||||||||||| 52 [H] COG0113 Delta-aminolevulinic acid dehydratase
11 22 30 50 ||||--|||--||-||||||--||||-||||||||||| 112 [EH] COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase
10 16 23 42 -----------||-|||||||-||||-||||||||||- 42 [H] COG0117 Pyrimidine deaminase
9 14 20 36 -|---------|--|-||-||-|||--||||||||||- 46 [H] COG0132 Dethiobiotin synthetase
14 27 37 62 ||||||||||||||||||||||||||-||||||||||| 120 [H] COG0142 Geranylgeranyl pyrophosphate synthase
11 24 33 54 |||||||||||||-||||||--||||-||||||||||- 102 [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I
11 18 25 44 -|--||-----||||-|||||-|-|--||||||||||| 78 [H] COG0156 7-keto-8-aminopelargonate synthetase and related enzymes
10 21 29 45 ||||-|||||-|--||||-|--||||-||||||||||- 50 [H] COG0157 Nicotinate-nucleotide pyrophosphorylase
9 14 20 37 -|---------||-|---|||-|||--||||||||||- 78 [H] COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
9 19 27 41 |||-||||||||--|-|||-|---|--||-|||||||| 46 [H] COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase
12 26 34 59 |||||||||||||-||||||-||||||||||-|||||- 65 [H] COG0171 NAD synthase
9 19 26 39 -|||||-||||||---||||--|||--||||-||-||- 73 [EH] COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes
11 23 32 52 |||||-|||||||-|-|||||-|||--||||||||||| 52 [H] COG0181 Porphobilinogen deaminase
6 14 22 34 -|||-||-|||-----|||-----|-||||||||-||- 55 [HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)
13 22 31 57 --|||---||-||-|||||||||||||||||||||||| 64 [H] COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase
10 17 24 48 -----------||-||||||-||||||||||||||||- 51 [H] COG0192 S-adenosylmethionine synthetase
11 18 25 49 -----------||-|||||||||||||||||||||||- 51 [H] COG0196 FAD synthase
12 21 31 52 |--|---||||||-|-|||||||||||||||||||||| 55 [H] COG0212 5-formyltetrahydrofolate cyclo-ligase
9 18 21 30 |||||||||||||--|--||--||||-----|------ 32 [H] COG0214 Pyridoxine biosynthesis enzyme
14 28 38 65 |||||||||||||||||||||||||||||||||||||| 67 [H] COG0237 Dephospho-CoA kinase
5 9 15 25 -----------||---|||---|----|||||||-||- 28 [H] COG0259 Pyridoxamine-phosphate oxidase
10 15 23 45 --|--------|||-|--|||-||||||||||||-||| 68 [H] COG0262 Dihydrofolate reductase
9 14 22 43 ----|------||-|-|||-|-|-||-||||||||||| 44 [H] COG0276 Protoheme ferro-lyase (ferrochelatase)
11 18 26 48 ---||------||-||||||-|||||-||||||||||| 54 [H] COG0285 Folylpolyglutamate synthase
12 25 35 57 |||||||||||||-|||||||-||||-||||||||||| 69 [H] COG0294 Dihydropteroate synthase and related enzymes
6 15 21 36 |||||||||||----|-----|-||||||-||------ 39 [H] COG0301 Thiamine biosynthesis ATP pyrophosphatase
9 15 23 41 --------||-||-|-||||--||||-||||||-|||| 44 [H] COG0302 GTP cyclohydrolase I
8 20 26 44 |||||||||||---|-|||---|||--||-|||-|||- 70 [H] COG0303 Molybdopterin biosynthesis enzyme
11 17 24 43 ---|-------||-|||||||-||||-||||||||||- 43 [H] COG0307 Riboflavin synthase alpha chain
8 17 20 29 |||||||||||||--|--|---||||-----|------ 31 [H] COG0311 Predicted glutamine amidotransferase involved in pyridoxine biosynthesis
8 18 24 41 |||||||-|||---|-|||---|-|--||-|||-|||- 45 [H] COG0314 Molybdopterin converting factor, large subunit
8 20 26 43 |||||||||||---|-|||---|||--||-|||-|||- 47 [H] COG0315 Molybdenum cofactor biosynthesis enzyme
10 14 23 40 ---|----|||||-|-|||-|-|-|--|||||||-||| 43 [H] COG0320 Lipoate synthase
6 10 17 31 --------|--||---|||---|----|||||||-||| 31 [H] COG0321 Lipoate-protein ligase B
13 24 32 54 ||||-||--|-||-||||||||||||-||||||||||| 58 [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase
12 24 33 54 |||||||||||||-|||-||-|||||-||||||||||- 66 [H] COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase
9 18 25 45 --|-|||----||-|-||||--||||-||||||||||- 60 [H] COG0352 Thiamine monophosphate synthase
8 19 23 34 |||||||||||-----||||--|||--||-|-|---|- 35 [H] COG0368 Cobalamin-5-phosphate synthase
10 20 27 42 |||||-|||||---|-|||||-|||--||||||||--- 42 [H] COG0373 Glutamyl-tRNA reductase
9 20 26 40 ||||-|||||----||||-|--|||--||||-|||||- 42 [H] COG0379 Quinolinate synthase
10 23 32 49 |||||||||||||-|-|||-|-|||--||||||||||| 77 [H] COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases
9 15 22 41 --|-|------||-|-|||-|-|-|--||||||||||| 54 [H] COG0407 Uroporphyrinogen-III decarboxylase
3 7 12 20 -----------||---||---------||||-|--||| 21 [H] COG0408 Coproporphyrinogen III oxidase
10 17 24 42 ---|-|--|||||-|||||---|||--||||-|||||- 46 [H] COG0413 Ketopantoate hydroxymethyltransferase
8 14 19 36 -----------||-|||||---|||--||||-|||||- 37 [H] COG0414 Panthothenate synthetase
10 21 27 38 ||||-|||||----||||||--|||--||||-|||||- 42 [H] COG0422 Thiamine biosynthesis protein ThiC
5 7 10 20 ---|--|---------||----|-||--|-||------ 20 [H] COG0447 Dihydroxynaphthoic acid synthase
12 25 34 55 |||||||||||||-||||||-|||||-||||||||||- 66 [H] COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase
11 22 31 50 |-|||||-|||||||-||||--||||-||||||||||- 86 [H] COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
8 19 23 31 |||||||||||||-||||----|----|-|--|--||- 32 [H] COG0499 S-adenosylhomocysteine hydrolase
10 19 25 41 |||----|---||-||||-||-|||--||||||||||- 49 [H] COG0502 Biotin synthase and related enzymes
11 24 33 54 |||||||||||||-||||||--||||-||||||||||- 79 [EH] COG0512 Anthranilate/para-aminobenzoate synthases component II
8 19 25 43 |||||||||||---|-|-|---|||--||-|||-|||- 54 [H] COG0521 Molybdopterin biosynthesis enzymes
10 20 25 38 |||-||||-|-||-||---|-|||||-||-|-||--|| 67 [HC] COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases
7 18 25 38 |||||||||||---|-||----|-|--|||||||||-- 38 [H] COG0611 Thiamine monophosphate kinase
10 16 24 46 --------------|||||||||||||||||||||||| 85 [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases
6 10 17 30 -----------||---|||---|-|--|||||||-||| 109 [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
9 15 22 43 --------------||||||-||||||||||||||||- 43 [H] COG0669 Phosphopantetheine adenylyltransferase
6 12 15 25 |||---||---|------|---|-|--||-|||---|- 34 [H] COG0684 Demethylmenaquinone methyltransferase
7 19 27 43 ||||||||||----||||-----||--||||||||||| 55 [H] COG0720 6-pyruvoyl-tetrahydropterin synthase
8 19 26 43 |||||||||||---|-|||---|-|--||-|||||||- 45 [H] COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A
10 16 24 44 -----------||-|||||||-||||-||||||||||| 48 [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase
11 18 25 45 ----|-|----||-|||||||-||||-||||||||||- 56 [H] COG0807 GTP cyclohydrolase II
7 12 16 30 --------------|||||---|||--|||--|||||- 31 [H] COG0853 Aspartate 1-decarboxylase
3 7 12 22 --------------|-||---------||||-|||||- 22 [H] COG0854 Pyridoxal phosphate biosynthesis protein
7 17 19 24 |||||-||||------||-|--|||--||---|---|- 25 [H] COG1010 Precorrin-3B methylase
9 16 24 40 ----||--|||||-|-||-|-|-|||-||-|||||||- 92 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases
7 14 17 25 |||||||-|||------||---|--|--|--||----- 29 [H] COG1056 Nicotinamide mononucleotide adenylyltransferase
9 16 22 45 -----------||-||||-|-||||||||||-|||||- 50 [H] COG1057 Nicotinic acid mononucleotide adenylyltransferase
11 20 22 32 |||||-|||-|---|||||||-|||---|-|---|--- 57 [HR] COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes
5 7 10 25 ----|------||---------|-||--|-||----|- 33 [H] COG1072 Panthothenate kinase
9 20 26 44 -||||||--||----|||||--|||||||-|||-|||- 118 [PH] COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components
10 15 22 40 --------------||||||||||||-||||||||||- 44 [HI] COG1154 Deoxyxylulose-5-phosphate synthase
5 6 9 19 ---|------------||----|-||--|-||------ 19 [H] COG1165 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
5 7 11 21 ---|------------||----|-||-||-||----|- 27 [HQ] COG1169 Isochorismate synthase
4 8 13 23 -----------||------|---||--||||||||--- 24 [H] COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
9 15 15 22 --||-||-|--||-|---|-|-|-|---|---|--|-- 22 [H] COG1232 Protoporphyrinogen oxidase
5 13 13 16 |||||-||--------|||---|----|----|----- 22 [H] COG1239 Mg-chelatase subunit ChlI
4 11 11 14 |||||--|--------||----|----|----|----- 15 [H] COG1240 Mg-chelatase subunit ChlD
8 19 23 30 |||||||||||-----||||--|||--||-|-|---|- 31 [H] COG1270 Cobalamin biosynthesis protein CobD/CbiB
2 9 11 13 |||||||||||--------------------------- 13 [KH] COG1339 Transcriptional regulator of a riboflavin/FAD biosynthetic operon
3 3 3 4 -|------------|---------|------------- 4 [H] COG1424 Pimeloyl-CoA synthetase
4 11 11 15 ||||---|--------||----|----|----|---|- 48 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases
1 1 3 8 ----------------------------|-||------ 8 [H] COG1441 O-succinylbenzoate synthase
9 12 19 30 --|-----------||--||||-|||-|||||||-||- 35 [H] COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis
12 24 32 54 --|||||||||||-||||||-||||||||||||||-|- 60 [H] COG1488 Nicotinic acid phosphoribosyltransferase
8 18 21 27 |||||-||-|------||||--|||--||-|-|--||- 31 [H] COG1492 Cobyric acid synthase
8 14 21 41 -----------||---|||||-||||-||||||||||- 47 [H] COG1539 Dihydroneopterin aldolase
7 10 12 13 |-|---|--|------|-||----|---|||-|----- 23 [H] COG1541 Coenzyme F390 synthetase
7 10 11 19 -----------||--|--||-|-|||--------|-|- 19 [H] COG1564 Thiamine pyrophosphokinase
7 8 11 21 ---|-----------|||-|--|-||--|-||------ 24 [H] COG1575 1,4-dihydroxy-2-naphthoate octaprenyltransferase
11 23 29 47 |||||-||||-||-|-|||||-|||--||||||||-|- 57 [H] COG1587 Uroporphyrinogen-III synthase
4 11 13 14 ||||-||||||||--|---------------------- 14 [H] COG1635 Flavoprotein involved in thiazole biosynthesis
8 18 23 37 |||||-|||-|||-|----|--|||--||||--|-||- 43 [H] COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)
2 9 11 12 |||||||||||--------------------------- 12 [EH] COG1685 Archaeal shikimate kinase
6 8 9 17 ---------------|-|||-|-||||----------- 20 [H] COG1713 Predicted HD superfamily hydrolase involved in NAD metabolism
2 6 8 8 |||---|||||--------------------------- 8 [H] COG1731 Archaeal riboflavin synthase
5 15 19 31 |||||||||||---|---------|---|-|||-|-|- 33 [H] COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein
5 10 14 18 |||--|||-||--------|-----|-||-||------ 22 [H] COG1767 Triphosphoribosyl-dephospho-CoA synthetase
8 18 20 26 |||||-||||------||||--|||--||---|---|- 28 [H] COG1797 Cobyrinic acid a,c-diamide synthase
8 14 19 30 ---|-||-|-|||-|-|-----||||-||-|-|--||- 44 [H] COG1893 Ketopantoate reductase
6 15 17 19 |||-|-||||------||-|---||--||---|---|- 19 [H] COG1903 Cobalamin biosynthesis protein CbiD
6 10 17 32 --|--------||---|-----|-||-||||||||||- 32 [HE] COG1932 Phosphoserine aminotransferase
4 7 10 16 ---------||||-----------|--||---|--||- 25 [FH] COG1953 Cytosine/uracil/thiamine/allantoin permeases
1 5 5 5 |||---||------------------------------ 6 [H] COG1962 Tetrahydromethanopterin S-methyltransferase, subunit H
8 16 21 36 --|||||-||----|-|||---|-|--||-|||-|||- 56 [H] COG1977 Molybdopterin converting factor, small subunit
12 23 32 51 ||||--|||||||-|||||||-||||-||||||||||- 61 [H] COG1985 Pyrimidine reductase, riboflavin biosynthesis
5 9 15 25 --------------|-||-|----|--||||||||||- 30 [H] COG1995 Pyridoxal phosphate biosynthesis protein
7 12 17 29 --------------|-||||--|||--||||-|||||- 29 [H] COG2022 Uncharacterized enzyme of thiazole biosynthesis
8 19 24 35 |||||||||||-----||||--|||--||-|-|--||- 36 [H] COG2038 NaMN:DMB phosphoribosyltransferase
6 11 11 12 ||--|--|-------||||----||-------|----- 12 [HR] COG2045 Phosphosulfolactate phosphohydrolase and related enzymes
6 15 17 21 ||-||-||||------||-|---||--||---|---|- 25 [H] COG2073 Cobalamin biosynthesis protein CbiG
7 17 19 24 |||||-||||------||-|--|||--||---|---|- 28 [H] COG2082 Precorrin isomerase
6 10 12 21 ----------------||||--|||--||-|-|---|- 22 [H] COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase
4 8 10 16 -----------||---||-----||---||-||----- 22 [H] COG2091 Phosphopantetheinyl transferase
6 11 12 16 ||--------------||-|--|||--||---|---|- 16 [H] COG2099 Precorrin-6x reductase
8 18 23 34 |-|||||-------|-||||--|||--||||-|||||- 36 [H] COG2104 Sulfur transfer protein involved in thiamine biosynthesis
8 14 16 26 --||||--|------|||||--|----||-|-|---|- 30 [H] COG2109 ATP:corrinoid adenosyltransferase
5 11 13 23 --|--||----||---------||||--|--|--|-|- 24 [H] COG2145 Hydroxyethylthiazole kinase, sugar kinase family
7 11 15 20 ---|----||-||-|-||----|----|-||-|--||- 22 [H] COG2154 Pterin-4a-carbinolamine dehydratase
12 18 26 45 --|-|---||-||-|||||||-|-|--||||||||||| 52 [H] COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis
4 8 15 24 -----------||---|||--------|||||||-||| 26 [H] COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase
6 9 12 20 -----------||-----|--|||-|-||--|---||- 26 [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase
7 17 19 25 |||||-||||------||-|--|||--||---|---|- 25 [H] COG2241 Precorrin-6B methylase 1
7 16 18 24 |||||-||||------||-|--|||--||-------|- 26 [H] COG2242 Precorrin-6B methylase 2
7 17 19 24 |||||-||||------||-|--|||--||---|---|- 26 [H] COG2243 Precorrin-2 methylase
2 9 11 13 |||||||||||--------------------------- 13 [H] COG2266 GTP:adenosylcobinamide-phosphate guanylyltransferase
7 17 19 24 |||||-||||------||-|--|||--||---|---|- 24 [H] COG2875 Precorrin-4 methylase
8 20 26 43 |||||||||||---|-|||---|||--||-|||-|||- 50 [H] COG2896 Molybdenum cofactor biosynthesis enzyme
2 3 6 11 -----------------------||--||-||------ 11 [H] COG2918 Gamma-glutamylcysteine synthetase
2 5 7 8 -----------||--------------|-|--|--|-| 8 [H] COG2941 Ubiquinone biosynthesis protein COQ7
1 2 6 12 ---------------------------||-||||---- 12 [H] COG2959 Uncharacterized enzyme of heme biosynthesis
4 6 8 13 -------------------|--|-|---|-||-|-|-- 19 [H] COG2978 Putative p-aminobenzoyl-glutamate transporter
3 5 5 5 |-------|---------------------|-|-|--- 5 [H] COG2998 ABC-type tungstate transport system, permease component
1 2 7 13 ---------------------------|||||||---- 13 [H] COG3071 Uncharacterized enzyme of heme biosynthesis
3 8 12 19 |||---||--------------|----||-||||---- 19 [H] COG3161 4-hydroxybenzoate synthetase (chorismate lyase)
3 3 5 11 ----------------------|--|-||--|------ 11 [H] COG3172 Predicted ATPase/kinase involved in NAD metabolism
3 4 6 14 ----------------------|--|-||--|--|--- 15 [H] COG3201 Nicotinamide mononucleotide transporter
1 6 6 6 ||||--||------------------------------ 6 [H] COG3252 Methenyltetrahydromethanopterin cyclohydrolase
3 4 5 9 ----------------------|--|---|-----||- 9 [H] COG3572 Gamma-glutamylcysteine synthetase
3 5 6 7 --|-------------|----------|---||---|- 9 [H] COG3585 Molybdopterin-binding protein
3 3 5 8 -------------------|-----|--|-||------ 9 [HI] COG3697 Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase)
1 2 4 12 ----------------------------|-||----|- 12 [H] COG3840 ABC-type thiamine transport system, ATPase component
5 7 8 10 --|--------||---------||||--|--------- 17 [GHR] COG3961 Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes
1 4 4 4 |||----|------------------------------ 6 [H] COG4054 Methyl coenzyme M reductase, beta subunit
1 4 4 4 |||----|------------------------------ 6 [H] COG4055 Methyl coenzyme M reductase, subunit D
1 4 4 4 |||----|------------------------------ 4 [H] COG4056 Methyl coenzyme M reductase, subunit C
1 4 4 4 |||----|------------------------------ 6 [H] COG4057 Methyl coenzyme M reductase, gamma subunit
1 4 4 4 |||----|------------------------------ 7 [H] COG4058 Methyl coenzyme M reductase, alpha subunit
1 4 4 4 |||----|------------------------------ 4 [H] COG4059 Tetrahydromethanopterin S-methyltransferase, subunit E
1 4 4 4 |||----|------------------------------ 4 [H] COG4060 Tetrahydromethanopterin S-methyltransferase, subunit D
1 4 4 4 |||----|------------------------------ 4 [H] COG4061 Tetrahydromethanopterin S-methyltransferase, subunit C
1 4 4 4 |||----|------------------------------ 4 [H] COG4062 Tetrahydromethanopterin S-methyltransferase, subunit B
1 4 4 4 |||----|------------------------------ 6 [H] COG4063 Tetrahydromethanopterin S-methyltransferase, subunit A
1 4 4 4 |||----|------------------------------ 4 [H] COG4064 Tetrahydromethanopterin S-methyltransferase, subunit G
1 1 2 6 ----------------------------|-|------- 6 [H] COG4138 ABC-type cobalamin transport system, ATPase component
1 1 2 6 ----------------------------|-|------- 6 [H] COG4139 ABC-type cobalamin transport system, permease component
5 8 10 20 ---|-|--|---------|--|------|-||-|--|- 21 [H] COG4143 ABC-type thiamine transport system, periplasmic component
4 4 5 10 ------|------------|-|------|--|------ 10 [H] COG4145 Na+/panthothenate symporter
1 3 6 10 ---------------------------||-|-|--||- 11 [H] COG4206 Outer membrane cobalamin receptor protein
1 4 4 4 |||----|------------------------------ 4 [H] COG4218 Tetrahydromethanopterin S-methyltransferase, subunit F
1 2 3 6 ----------------------------|------||- 6 [H] COG4547 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase)
3 4 6 10 --|----------------------|--|-||----|- 10 [CH] COG4635 Flavodoxin
3 5 5 5 |-------|---------------------|-|-|--- 5 [H] COG4662 ABC-type tungstate transport system, periplasmic component
3 4 4 4 -------------------|---||---|--------- 5 [H] COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase
2 3 3 3 -----------||---|--------------------- 6 [H] COG5031 Uncharacterized protein involved in ubiquinone biosynthesis
2 3 3 3 -----------||-----------|------------- 3 [H] COG5146 Pantothenate kinase, acetyl-CoA regulated
4 5 6 7 ----|----|----------|------|--------|| 8 [H] COG5424 Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C
2 2 2 3 --|---------------------------------|- 13 [H] COG5598 Trimethylamine:corrinoid methyltransferase