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10 21 30 46 |||--||||||||-|||||---||||-||||||||||- 48 [E] COG0002 Acetylglutamate semialdehyde dehydrogenase
14 28 38 65 |||||||||||||||||||||||||||||||||||||| 131 [E] COG0006 Xaa-Pro aminopeptidase
8 21 29 41 |||||||||||||---||||---|||-||||||||-|- 78 [E] COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family
10 16 23 39 --|--------||-|||||--|||||-||||||||||- 41 [E] COG0014 Gamma-glutamyl phosphate reductase
9 20 27 47 |||-|-||---||-|||||---||||-||||||||||- 76 [E] COG0019 Diaminopimelate decarboxylase
10 22 31 49 |||-|||||||||-|||||---||||-||||||||||- 146 [EH] COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]
11 20 29 50 --||||--|||||-||||||--||||-||||||||||- 103 [E] COG0031 Cysteine synthase
10 21 28 44 ||||--||||-||-|||||---||||-|||||-||||- 45 [E] COG0040 ATP phosphoribosyltransferase
10 20 28 47 |||--|||||-|--|||||---||||-||||||||||- 49 [EH] COG0059 Ketol-acid reductoisomerase
10 22 30 47 ||||-|||||-||-|||||---||||-||||||||||- 56 [E] COG0065 3-isopropylmalate dehydratase large subunit
10 21 29 47 |||--|||||-||-|||||---||||-||||||||||- 57 [E] COG0066 3-isopropylmalate dehydratase small subunit
10 20 26 39 |||---||||-||-|||||---||||-||||-|-|||- 45 [E] COG0067 Glutamate synthase domain 1
10 20 26 39 |||---||||-||-|||||---||||-||||-|-|||- 52 [E] COG0069 Glutamate synthase domain 2
10 20 26 39 |||---||||-||-|||||---||||-||||-|-|||- 46 [E] COG0070 Glutamate synthase domain 3
9 20 26 33 ||||||||||||--|||||----|||-||-|---|||- 43 [E] COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase
7 15 18 26 ||||-|||--||----||----|-||--|-||----|- 46 [E] COG0076 Glutamate decarboxylase and related PLP-dependent proteins
10 22 30 47 |||||-||||-||-|||||---||||-||||||||||- 47 [E] COG0077 Prephenate dehydratase
11 25 34 54 |||||||||||||-|||||--||||||||||||||||- 65 [E] COG0078 Ornithine carbamoyltransferase
11 24 33 51 |||||||||||||-||||||--||||-||||||||||- 96 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase
12 25 34 56 |||||||||||||-|||||||-||||-||||||||||- 56 [E] COG0082 Chorismate synthase
10 18 24 41 -|-|||-||||||-|||||---||||--||||--|--- 41 [E] COG0083 Homoserine kinase
10 21 29 45 ||||--||||-||-|||||---||||-||||||||||- 45 [E] COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase
10 21 29 45 ||||--||||-||-|||||---||||-||||||||||- 47 [E] COG0107 Imidazoleglycerol-phosphate synthase
10 23 31 49 |||||||||||||-|||||---||||-||||||-|||- 113 [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases
13 27 37 64 |||||||||||||||||||-|||||||||||||||||| 79 [E] COG0112 Glycine/serine hydroxymethyltransferase
11 22 30 50 ||||--|||--||-||||||--||||-||||||||||| 112 [EH] COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase
10 21 29 45 ||||--||||-||-|||||---||||-||||||||||- 47 [E] COG0118 Glutamine amidotransferase
10 22 30 47 |||-||||||-||-|||||---||||-||||||||||- 102 [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases
12 25 34 56 |||||||||||||-|||||||-||||-||||||||||- 58 [E] COG0128 5-enolpyruvylshikimate-3-phosphate synthase
10 21 30 49 |||--||||||||-|||||---||||-||||||||||- 85 [EG] COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase
10 21 29 45 ||||--||||-||-|||||---||||-||||||||||- 45 [E] COG0131 Imidazoleglycerol-phosphate dehydratase
11 23 30 49 ||||-|||---||-|||||||-||||-||||||||||- 50 [E] COG0133 Tryptophan synthase beta chain
10 23 32 52 |||||||||||||-|||||---||||-||||||||||- 56 [E] COG0134 Indole-3-glycerol phosphate synthase
11 24 33 50 |||||||||||||-|||||-|-||||-||||||||||- 50 [E] COG0135 Phosphoribosylanthranilate isomerase
11 24 34 56 |||||||||||||-|||||-|-||||-||||||||||| 68 [E] COG0136 Aspartate-semialdehyde dehydrogenase
10 22 30 47 |||||-||||-||-|||||---||||-||||||||||- 47 [E] COG0137 Argininosuccinate synthase
10 21 29 45 ||||--||||-||-|||||---||||-||||||||||- 45 [E] COG0139 Phosphoribosyl-AMP cyclohydrolase
10 20 28 44 ||||---|||-||-|||||---||||-||||||||||- 44 [E] COG0140 Phosphoribosyl-ATP pyrophosphohydrolase
10 21 29 45 ||||--||||-||-|||||---||||-||||||||||- 50 [E] COG0141 Histidinol dehydrogenase
8 15 18 23 -||-|-|||||||-|-||----|-|---------|||- 49 [EQ] COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit
7 13 16 20 -||-|--||||||-|-||----|-----------|||- 29 [EQ] COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit
11 24 33 54 |||||||||||||-||||||--||||-||||||||||- 102 [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I
11 24 33 53 |||||||||||||-|||||-|-||||-||||||||||- 54 [E] COG0159 Tryptophan synthase alpha chain
8 15 20 34 --||||--|||||---|-|---|||--||-|||---|- 69 [E] COG0160 4-aminobutyrate aminotransferase and related aminotransferases
10 22 30 47 |||||-||||-||-|||||---||||-||||||||||- 51 [E] COG0165 Argininosuccinate lyase
12 25 34 56 |||||||||||||-|||||||-||||-||||||||||- 78 [E] COG0169 Shikimate 5-dehydrogenase
10 22 32 54 |||||||||||||-|||||---|-||-||||||||||| 101 [E] COG0174 Glutamine synthetase
9 19 26 39 -|||||-||||||---||||--|||--||||-||-||- 73 [EH] COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes
8 13 19 30 -|--|------|||---|-|--||---||||||||||- 39 [E] COG0241 Histidinol phosphatase and related phosphatases
8 20 28 46 |||||||||||||-----||--||||-||||||||-|- 64 [EJ] COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D
9 17 24 44 ||----||------||||-||-|||--||||||||||| 46 [E] COG0253 Diaminopimelate epimerase
11 16 23 44 ----------|-|||-|||||-|-|-|||||||||||| 61 [E] COG0260 Leucyl aminopeptidase
10 16 23 39 --|--------||-|||||--|||||-||||||||||- 43 [E] COG0263 Glutamate 5-kinase
10 22 31 50 |||||-|||||||-|||||---||||-||||||||||- 51 [E] COG0287 Prephenate dehydrogenase
8 17 25 45 |||---||------||||--|-||||-||||||||||| 46 [E] COG0289 Dihydrodipicolinate reductase
9 14 21 36 --|-|---||-|||--|||---|--|-|||||||-||- 51 [E] COG0308 Aminopeptidase N
10 22 32 56 |||||||||||---||||-||-||||-||||||||||| 114 [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase
11 21 28 42 --|||||-|||||--||||||-||||-||--||||||- 66 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase
11 18 27 49 ----||--|||||--||||||-||||-||||||||||- 50 [E] COG0337 3-dehydroquinate synthetase
5 9 15 24 -----------||---|||---|----|||||||-||- 30 [E] COG0339 Zn-dependent oligopeptidases
11 19 28 48 |-|-|---|||||-|||||--|||||-||||||||||- 56 [E] COG0345 Pyrroline-5-carboxylate reductase
9 19 27 45 |-||-||--||||---||||--||||-||||||||||- 252 [E] COG0346 Lactoylglutathione lyase and related lyases
8 16 23 35 |||---||------|||||---||||-|||||||-||- 67 [E] COG0347 Nitrogen regulatory protein PII
7 17 22 34 |||||||||-||||--------||||-||||-----|- 52 [E] COG0367 Asparagine synthase (glutamine-hydrolyzing)
10 16 21 35 ---|||---||||-|||||---|-|--|||--||-||- 36 [E] COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain
10 16 21 36 ---|||---||||-|||||---|-|--|||--||-||- 79 [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase)
10 15 22 34 ----|---||||||--||||--|-|--||||-|||||- 48 [E] COG0405 Gamma-glutamyltransferase
9 14 18 25 -|----|-|||----|||||--|-||-||---|-|-|- 72 [E] COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
8 13 16 23 -|----|-|||----|||||-----|-||---|-|-|- 60 [E] COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
9 18 24 34 -|--|||||||||-||--|---||||-|||--|||-|- 41 [E] COG0421 Spermidine synthase
13 26 36 59 |||||||||||||-||||||||||||-||||||||||| 193 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase
10 21 27 45 |||--|||--|||-|||||---||||-||-|||||||- 50 [E] COG0440 Acetolactate synthase, small (regulatory) subunit
11 20 26 47 --|||||-|||---||--|||||||||||-|||-|-|- 163 [EP] COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
11 23 31 51 |||||-||||-||-||||||--||||-||||||||||- 66 [EF] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
10 23 32 53 |||||||||||||-|||||---||||-||||||||||- 62 [E] COG0460 Homoserine dehydrogenase
12 26 36 62 |||||||||||||-||||||-||||||||||||||||| 76 [FE] COG0462 Phosphoribosylpyrophosphate synthetase
10 21 30 48 |||--|||||-||-|||||---||||-||||||||||| 75 [CE] COG0473 Isocitrate/isopropylmalate dehydrogenase
14 28 38 65 |||||||||||||||||||||||||||||||||||||| 537 [GEPR] COG0477 Permeases of the major facilitator superfamily
12 19 26 42 --|-||--|-||||||-||--|||||-||||-|-|||| 77 [ER] COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
10 23 32 53 |||||||||||||-|||||---||||-||||||||||- 70 [E] COG0498 Threonine synthase
11 23 31 51 |||||-||||-||-||||||--||||-||||||||||- 55 [EF] COG0505 Carbamoylphosphate synthase small subunit
7 12 16 30 ---|-------||---|||---|-|--||--||||||- 32 [E] COG0506 Proline dehydrogenase
11 18 25 41 ---|||---||||-|||||-|-|-|||||||-||-||- 50 [E] COG0509 Glycine cleavage system H protein (lipoate-binding)
11 24 33 54 |||||||||||||-||||||--||||-||||||||||- 79 [EH] COG0512 Anthranilate/para-aminobenzoate synthases component II
12 22 29 53 |-||-|-|-||-|--||||||||||||||||||-|||- 89 [E] COG0520 Selenocysteine lyase
11 24 34 56 |||||||||||||-|||||-|-||||-||||||||||| 85 [E] COG0527 Aspartokinases
10 22 31 53 |||||-||||||||--||-||-|||||||||||--||| 257 [E] COG0531 Amino acid transporters
10 23 32 52 |||||||||||||-|||||---||||-||||||||||- 66 [E] COG0547 Anthranilate phosphoribosyltransferase
10 21 31 47 |||--||||||||-|||||---||||-||||||||||| 60 [E] COG0548 Acetylglutamate kinase
5 9 13 20 ---|||--|-|------|------|||||--|----|- 30 [E] COG0549 Carbamate kinase
9 14 18 25 -|----|-|||----|||||--|-||-||---|-|-|- 73 [E] COG0559 Branched-chain amino acid ABC-type transport system, permease components
8 20 27 43 |||||||||-|||------||-||-|-||||||||||- 76 [E] COG0560 Phosphoserine phosphatase
9 18 25 41 |-|||||--||||----|-||-|-||-||-|||||-|| 70 [ER] COG0591 Na+/proline symporter
12 22 28 52 --|||||-|||---|||||||||||||||-|||-|-|- 244 [EP] COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components
9 20 29 46 |||||||||||||-||----|-|-||-||||||||||- 60 [E] COG0620 Methionine synthase II (cobalamin-independent)
11 20 30 53 -|--|||||||||-||--|||-||||-||||||||||| 157 [E] COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases
9 17 26 47 --||||--|||||--|--||--||||-||||||||||- 107 [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases
7 11 14 27 ---------------|||||--|||--||-|-|--||- 30 [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain
11 21 30 51 --|||||-|||||-|-|||-||||||-||||||||||- 225 [E] COG0665 Glycine/D-amino acid oxidases (deaminating)
9 15 19 26 -|-|--|-|||----|||||--|-||-||---|-|-|- 112 [E] COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
10 18 27 43 --|-||--|||||-|||||---||||-||||||||||- 51 [E] COG0685 5,10-methylenetetrahydrofolate reductase
5 8 10 17 ----------------|||---|-||----|---|||- 20 [E] COG0686 Alanine dehydrogenase
9 15 22 38 ---|--|-|-|----|||||-|-||||||-||||-||- 114 [E] COG0687 Spermidine/putrescine-binding periplasmic protein
14 25 35 57 |-|||||-||||||||||||||||||-||||||||||| 386 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily
11 17 24 45 --|--------||-|||||||-||||-||||||||||- 52 [E] COG0703 Shikimate kinase
4 7 10 15 -|-----|||----|------------||--|--|-|- 15 [E] COG0709 Selenophosphate synthase
7 16 18 28 ||||||||||-||-|-----|---||--|----|---- 28 [E] COG0710 3-dehydroquinate dehydratase
6 9 15 23 -----------||---|-|---|--|-|||||||-||- 40 [E] COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase
11 20 26 46 --|||||-|||---|||||||-||||-||-|||-|-|- 248 [E] COG0747 ABC-type dipeptide transport system, periplasmic component
2 4 6 12 -----------------|----------|--|--|||- 21 [E] COG0754 Glutathionylspermidine synthase
7 12 17 28 ---------------|||||--|||--||||||-|||- 31 [E] COG0757 3-dehydroquinate dehydratase II
10 16 24 41 --|---|-|-|----||||||-||||-||-|||||||| 191 [E] COG0765 ABC-type amino acid transport system, permease component
5 7 10 16 -----------------|-|--|-|--||-||-||--- 19 [E] COG0786 Na+/glutamate symporter
6 11 13 23 ------------|---|||---|-|-|||--||-|-|- 25 [E] COG0804 Urea amidohydrolase (urease) alpha subunit
5 8 11 20 -----------|||------|-|----||-||-||--- 75 [E] COG0814 Amino acid permeases
6 11 13 23 ------------|---|||---|-|-|||--||-|-|- 25 [E] COG0831 Urea amidohydrolase (urease) gamma subunit
6 11 13 22 ------------|---|||---|-|-|||--||-|-|- 24 [E] COG0832 Urea amidohydrolase (urease) beta subunit
3 7 9 16 -----------||----------|||-||---|-|--- 54 [E] COG0833 Amino acid transporters
11 17 25 46 --|---|-|-|----|||||||||||-||-|||||||| 270 [ET] COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain
10 16 21 35 ---|||---||||-|||||---|-|--|||--||-||- 36 [E] COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain
6 10 13 24 ----|----------||-----|||--||-||-||-|- 25 [E] COG1027 Aspartate ammonia-lyase
7 13 19 39 --||--------|--|||----||||-||-|||||||- 53 [E] COG1045 Serine acetyltransferase
9 18 26 41 --|||||--||||--||-|---||||||||||||-||- 159 [ER] COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
13 20 27 49 --|---|----|||||||||||||||-||-|||||||| 76 [E] COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes
3 5 7 19 ----------------------||||-||-------|- 77 [E] COG1113 Gamma-aminobutyrate permease and related permeases
6 7 11 19 -------------------|||||||-||-||------ 24 [E] COG1114 Branched-chain amino acid permeases
8 12 16 29 --|--|------------|||||-||-||-||-||-|- 57 [E] COG1115 Na+/alanine symporter
5 8 9 19 --|-|--------------||---|||-|-------|- 28 [EP] COG1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
7 10 12 25 ------|---------|-||--||||-||-----|-|- 31 [E] COG1125 ABC-type proline/glycine betaine transport systems, ATPase components
10 16 24 41 --|---|-|-|----||||||-||||-||-|||||||| 130 [E] COG1126 ABC-type polar amino acid transport system, ATPase component
8 12 14 29 --||-----------|--||||--|||---|---|||- 41 [E] COG1164 Oligoendopeptidase F
3 6 10 17 ----------------|||--------|||||-||--- 18 [E] COG1166 Arginine decarboxylase (spermidine biosynthesis)
10 15 22 38 ----||--|||||--||-||--||||-||-|||--||- 107 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
5 7 9 19 ------------------||--||||--|--||----- 21 [E] COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
10 16 26 44 ---||---|||||--|||||--|-||-||||||||||| 75 [E] COG1171 Threonine dehydratase
12 22 28 51 --|||||-|||---|||||||||||||||-|||-|-|- 241 [EP] COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components
7 11 13 26 ------|---------|-||--||||-||---|-|-|- 54 [E] COG1174 ABC-type proline/glycine betaine transport systems, permease component
9 14 21 37 ---|--|-|-|----||-||-|-||||||-||||-||- 88 [E] COG1176 ABC-type spermidine/putrescine transport system, permease component I
9 15 22 38 ---|--|-|-|----||-||-|-||||||-|||||||- 98 [E] COG1177 ABC-type spermidine/putrescine transport system, permease component II
5 8 9 11 ----------------|||---|-|--|----|--||- 12 [E] COG1231 Monoamine oxidase
6 8 12 21 --||----------|---|---|-|--||-||||---- 23 [E] COG1246 N-acetylglutamate synthase and related acetyltransferases
8 15 22 32 |-|-|-|||||----|-||---|-|--||||||-|||- 127 [E] COG1280 Putative threonine efflux protein
6 10 15 29 --|---|-----------||--|-||-||-|||||-|- 35 [E] COG1296 Predicted branched-chain amino acid permease (azaleucine resistance)
9 17 21 29 |-|--|||||----|||||---|||--|-|-||--||- 74 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases
7 8 8 11 -----------||--|---|-|||---|---------- 14 [E] COG1362 Aspartyl aminopeptidase
9 18 21 31 |||---||---||-|||||---||||-|----||-||- 33 [E] COG1364 N-acetylglutamate synthase (N-acetylornithine aminotransferase)
9 18 20 30 |||-||||---||-||--||--||||--|-|-----|- 40 [ER] COG1387 Histidinol phosphatase and related hydrolases of the PHP family
6 10 15 25 ---------------||||---|||--||||||--||- 28 [E] COG1410 Methionine synthase I, cobalamin-binding domain
5 10 13 18 ---|||--||--|---||----------|-|-|--||- 21 [E] COG1446 Asparaginase
4 7 12 20 -----------||------||------|||||||--|- 31 [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase
2 7 7 7 ||||--||------|----------------------- 7 [E] COG1465 Predicted alternative 3-dehydroquinate synthase
5 6 8 13 -----|----------|-|---|----------|-||| 17 [E] COG1505 Serine proteases of the peptidase family S9A
8 12 17 21 ---|||--|||||----|||----|--|-|-----||| 48 [E] COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases
8 10 14 22 -||-----------||--||-|--|---||||---||- 25 [E] COG1509 Lysine 2,3-aminomutase
6 11 15 23 -|--|||-|||---||-------||--|||--|----- 28 [E] COG1586 S-adenosylmethionine decarboxylase
10 21 30 51 |||||-|||||||-||--||--||||-||||||||||- 68 [E] COG1605 Chorismate mutase
2 9 11 12 |||||||||||--------------------------- 12 [EH] COG1685 Archaeal shikimate kinase
5 6 6 8 --|----------------|--|-|------|--|--- 9 [E] COG1687 Predicted branched-chain amino acid permeases (azaleucine resistance)
6 11 12 19 ---||||--||-------|---|-|---|---|--|-- 21 [E] COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family
7 13 16 22 ----|||-|-|||---|||-----||----||--|-|- 26 [E] COG1748 Saccharopine dehydrogenase and related proteins
5 9 15 34 ------------------||--||||-||-|||||||- 58 [E] COG1760 L-serine deaminase
4 5 10 21 ----------------|-----|--|-||||----||| 23 [E] COG1770 Protease II
4 6 6 8 -|----||-----------|---|----|--------- 10 [E] COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB
4 11 13 15 |||||||||||---|----------|------------ 16 [E] COG1812 Archaeal S-adenosylmethionine synthetase
6 9 9 12 --|-------|-----||----|||--|--------|- 14 [E] COG1834 N-Dimethylarginine dimethylaminohydrolase
3 6 8 16 ---------------|-------|||--|-|---|-|- 16 [E] COG1897 Homoserine trans-succinylase
3 8 10 19 ||--|--|------|------------||--|--|-|- 21 [E] COG1921 Selenocysteine synthase [seryl-tRNASer selenium transferase]
6 10 17 32 --|--------||---|-----|-||-||||||||||- 32 [HE] COG1932 Phosphoserine aminotransferase
5 9 13 23 ----------------||-|--||||-||-|||---|- 46 [E] COG1982 Arginine/lysine/ornithine decarboxylases
7 10 15 26 -----|-----|------||--|-|--||-|||||||- 31 [E] COG1984 Allophanate hydrolase subunit 2
8 12 15 24 ---|-------||--||-||---||--||-|-|--||- 27 [E] COG2008 Threonine aldolase
6 11 15 21 |-||-------||-----|---|-|--|-|-|||-||- 25 [E] COG2021 Homoserine acetyltransferase
5 8 8 11 -----------||----|----|||---|-------|- 13 [E] COG2040 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)
7 10 15 25 -----|-----|------||--|-|--||-|||||||- 30 [E] COG2049 Allophanate hydrolase subunit 1
1 5 5 5 |||---||------------------------------ 5 [E] COG2061 ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase
5 8 11 19 ----------------||-|--|-|--||-|-|--||- 27 [E] COG2066 Glutaminase
4 6 8 17 --|------------------|--||-||---|---|- 40 [E] COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components
5 9 17 37 -------|-------|------||||-||||||||||| 38 [E] COG2171 Tetrahydrodipicolinate N-succinyltransferase
6 9 13 23 --|---------------||-|-|||--|-||--|||- 39 [E] COG2195 Di- and tripeptidases
6 9 12 18 ---||----|-----------||-|||||-|-----|- 21 [E] COG2235 Arginine deiminase
6 12 14 22 ||-|---|--------|-|---|-|--||---|-|||- 74 [E] COG2303 Choline dehydrogenase and related flavoproteins
7 9 10 16 ---|-|-|--|---|---|--|--||----------|- 24 [E] COG2309 Leucyl aminopeptidase (aminopeptidase T)
6 8 12 15 ---|-|--|||-------||----|---|-|-----|| 15 [E] COG2317 Zn-dependent carboxypeptidase
7 9 12 18 -----|--|||-|-----|-|---|--|----|--||- 26 [E] COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog
5 6 6 8 -----|----|-------|-----|-------|---|- 8 [E] COG2362 D-aminopeptidase
6 14 17 21 |-|||-|||||||---------|-|--||---|---|- 37 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog
4 5 6 12 -------------------|-|---||-|--|------ 12 [E] COG2502 Asparagine synthetase A
5 8 10 15 -----|------|--||-----------|-|-|-|||- 16 [E] COG2515 1-aminocyclopropane-1-carboxylate deaminase
5 7 12 20 --|----------------|--||||-||-||||---- 51 [GE] COG2610 H+/gluconate symporter and related permeases
1 2 5 9 ---------------------------||||----|-- 11 [E] COG2716 Glycine cleavage system regulatory protein
6 12 18 32 ---------|-||---||----||||-||-|||||||- 63 [E] COG2755 Lysophospholipase L1 and related esterases
7 10 12 16 ----------------|-||-|||||---|--||--|- 19 [E] COG2856 Predicted Zn peptidase
5 8 10 16 --|--------||----|------|--||---||-|-- 19 [E] COG2866 Predicted carboxypeptidase
7 13 15 21 --||-------||--|--|---||||-|---||-|-|- 25 [E] COG2873 O-acetylhomoserine sulfhydrylase
9 12 15 20 ----||--|||----||||||--|||-------|---- 22 [E] COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase
3 5 9 15 -----------||---------|----|-||----||| 15 [E] COG2902 NAD-specific glutamate dehydrogenase
3 6 6 6 -----------||-----|----------|--|--|-- 10 [E] COG2939 Carboxypeptidase C (cathepsin A)
3 5 7 10 ------------------|------|-|||----||-- 10 [E] COG2957 Peptidylarginine deiminase and related enzymes
2 3 6 14 -----------------|---------||-||----|- 14 [E] COG2981 Uncharacterized protein involved in cysteine biosynthesis
5 8 12 19 ---||-------------||----||-||-|-|--||- 29 [E] COG2986 Histidine ammonia-lyase
5 8 12 18 ---||-------------||----||-||-|-|--||- 19 [E] COG2987 Urocanate hydratase
2 3 5 9 ----------------||---------||-|------- 9 [E] COG2988 Succinylglutamate desuccinylase
4 4 6 8 ---|------|--------|--------|-||------ 10 [E] COG3033 Tryptophanase
3 3 5 9 -------------------|----|--||-|------- 9 [E] COG3048 D-serine dehydratase
1 1 3 8 ----------------------------|-||------ 8 [KE] COG3060 Transcriptional regulator of met regulon
2 2 4 9 ---|------------------------|-||------ 9 [E] COG3075 Anaerobic glycerol-3-phosphate dehydrogenase
5 9 12 19 -----------|||--------||||--|||--|-|-- 32 [E] COG3104 Dipeptide/tripeptide permease
1 2 4 8 ---------------------------||-|----|-- 10 [E] COG3138 Arginine/ornithine N-succinyltransferase beta subunit
3 6 8 10 ----------------||----|----|--|-|--||- 15 [ER] COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins
2 4 6 6 --------------------|------|--|-|--||- 6 [E] COG3186 Phenylalanine-4-hydroxylase
5 7 8 15 -----|---|--------|---|----|----|--||- 21 [EQ] COG3191 L-aminopeptidase/D-esterase
3 3 4 8 -------------------|----|--||--------- 8 [E] COG3192 Ethanolamine utilization protein
2 4 5 13 ----------------------|----|------|||- 15 [E] COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase
4 5 6 7 --|-------------|------||--|--|------- 11 [E] COG3227 Zinc metalloprotease (elastase)
2 4 7 8 ------------------|--------||-|||---|- 9 [E] COG3232 5-carboxymethyl-2-hydroxymuconate isomerase
1 1 4 9 ---------------------------||-||------ 10 [KE] COG3283 Transcriptional regulator of aromatic amino acids metabolism
6 6 7 13 ----------------|-||--|-|---|--|------ 14 [E] COG3340 Peptidase E
5 6 6 7 ----|----------|--||---|-|------------ 8 [E] COG3404 Methenyl tetrahydrofolate cyclohydrolase
3 4 4 6 ---------------|--------|---|-------|- 6 [E] COG3457 Predicted amino acid racemase
2 4 5 5 ------------------|--------|----|--||- 6 [E] COG3483 Tryptophan 2,3-dioxygenase (vermilion)
3 3 4 6 -----------|---------|--||------------ 6 [E] COG3579 Aminopeptidase C
2 3 4 10 ------------------------||--|-------|- 18 [E] COG3591 V8-like Glu-specific endopeptidase
4 7 8 13 -----------||------|--|----|----|--||- 21 [E] COG3616 Predicted amino acid aldolase or racemase
2 4 7 13 -------------------------|-||-||-||--- 13 [E] COG3633 Na+/serine symporter
4 4 4 5 ----|----------|---|-----|------------ 6 [E] COG3643 Glutamate formiminotransferase
5 9 12 18 --------------|-|||----|||-|----||-||- 18 [E] COG3705 ATP phosphoribosyltransferase involved in histidine biosynthesis
1 2 3 7 ---------------------------||------|-- 8 [E] COG3724 Succinylarginine dihydrolase
2 3 5 8 ------------------|--------||------||- 13 [E] COG3741 N-formylglutamate amidohydrolase
2 3 3 4 ---|------------------------|-------|- 5 [E] COG3799 Methylaspartate ammonia-lyase
10 18 25 42 --||--|-|-|----|||||-||||||||-|||||||- 144 [E] COG3842 ABC-type spermidine/putrescine transport systems, ATPase components
4 6 6 6 ---|-------|------|--------|----|---|- 6 [E] COG3844 Kynureninase
2 3 3 7 --------------------|--||------------- 7 [E] COG3869 Arginine kinase
1 2 2 5 ---------------------------|--------|- 10 [E] COG3931 Predicted N-formylglutamate amidohydrolase
1 2 2 5 ---------------------------|--------|- 11 [E] COG3938 Proline racemase
3 5 6 12 ----------------------|-|---|---|--||- 13 [E] COG3962 Acetolactate synthase
2 3 4 9 ----------------|-----------|-|--|---- 9 [E] COG3977 Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase
3 3 3 6 ----------------|-------|-----------|- 7 [E] COG4091 Predicted homoserine dehydrogenase
3 4 4 6 -----|-----||-----------------------|- 10 [E] COG4126 Hydantoin racemase
1 2 5 12 ---------------------------||-||----|- 26 [E] COG4160 ABC-type arginine/histidine transport system, permease component
1 1 3 8 ----------------------------|-||------ 8 [E] COG4161 ABC-type arginine transport system, ATPase component
7 12 16 33 ---------------|---||||||||||-|||-|-|- 88 [E] COG4166 ABC-type oligopeptide transport system, periplasmic component
4 6 8 17 --|------------------|--||-||---|---|- 27 [E] COG4175 ABC-type proline/glycine betaine transport system, ATPase component
4 6 8 17 --|------------------|--||-||---|---|- 28 [E] COG4176 ABC-type proline/glycine betaine transport system, permease component
9 14 18 25 -|----|-|||----|||||--|-||-||---|-|-|- 72 [E] COG4177 ABC-type branched-chain amino acid transport system, permease component
3 4 4 4 ------------------|----||-----------|- 5 [E] COG4187 Arginine degradation protein (predicted deacylase)
1 2 5 12 ---------------------------||-||----|- 26 [E] COG4215 ABC-type arginine transport system, permease component
3 5 6 9 -------------------|---||--||---|----- 9 [E] COG4302 Ethanolamine ammonia-lyase, small subunit
3 5 6 9 -------------------|---||--||---|----- 9 [E] COG4303 Ethanolamine ammonia-lyase, large subunit
1 3 3 6 ---------------------------|----|---|- 14 [E] COG4311 Sarcosine oxidase delta subunit
2 4 4 4 -----------||----------||------------- 4 [E] COG4359 Uncharacterized conserved protein, possibly involved in methylthioadenosine recycling
2 2 2 4 ------------------|-----|------------- 4 [PE] COG4362 Nitric oxide synthase, oxygenase domain
2 3 3 5 ----------------||------|------------- 5 [E] COG4401 Chorismate mutase
2 3 4 4 ------------------------|--||-------|- 4 [E] COG4413 Urea transporter
2 3 3 6 ----------------||------------------|- 6 [E] COG4448 L-asparaginase II
1 3 3 6 ---------------------------|----|---|- 13 [E] COG4583 Sarcosine oxidase gamma subunit
2 3 4 9 ----------------|-----------|-|-----|- 9 [E] COG4597 ABC-type amino acid transport system, permease component
1 2 4 10 ---------------------------||-|-----|- 13 [E] COG4598 ABC-type histidine transport system, ATPase component
11 20 26 46 --|||||-|||---||--|||||||||||-|||-|-|- 143 [E] COG4608 ABC-type oligopeptide transport system, ATPase component
3 3 4 5 --|----------------------|-||--------- 7 [E] COG4690 Dipeptidase
3 4 4 7 -------------------|----|---|-------|- 7 [E] COG4766 Ethanolamine utilization protein
3 3 3 6 -------------------|----|---|--------- 7 [E] COG4810 Ethanolamine utilization protein
3 3 3 6 -------------------|----|---|--------- 6 [E] COG4812 Ethanolamine utilization cobalamin adenosyltransferase
3 3 3 6 -------------------|----|---|--------- 8 [E] COG4816 Ethanolamine utilization protein
3 3 3 6 -------------------|----|---|--------- 6 [E] COG4819 Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition
3 3 3 6 -------------------|----|---|--------- 6 [E] COG4820 Ethanolamine utilization protein, possible chaperonin
3 3 3 4 ---|---------------|--------|--------- 4 [E] COG4865 Glutamate mutase epsilon subunit
3 3 3 6 -------------------|----|---|--------- 9 [E] COG4917 Ethanolamine utilization protein
10 21 30 46 |||--||||||||-|||||---||||-||||||||||- 71 [E] COG4992 Ornithine/acetylornithine aminotransferase
1 1 2 5 -----------------------------------||- 7 [E] COG5425 Usg protein, probable subunit of phosphoribosylanthranilate isomerase
2 3 3 3 -----------||----------------|-------- 3 [E] COG5630 Acetylglutamate synthase