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258 COGs C Energy production and conversion
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10 16 21 35 ---||---||||||--|||-|-|-||||----|--|||  56 [C]  COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
13 26 34 55 |||||-|||||||-|||||||||||||-|||||-||||  71 [C]  COG0039 Malate/lactate dehydrogenases
10 20 29 46 ||-||-|||||||-|-|||-|-|-|--|||||||||||  50 [C]  COG0045 Succinyl-CoA synthetase, beta subunit
 9 16 24 48 --|--------||-||||-|--||||||||||||||||  53 [C]  COG0055 F0F1-type ATP synthase, beta subunit
 9 16 24 48 --|--------||-||||-|--||||||||||||||||  53 [C]  COG0056 F0F1-type ATP synthase, alpha subunit
10 20 29 46 ||-||-|||||||-|-|||-|-|-|--|||||||||||  57 [C]  COG0074 Succinyl-CoA synthetase, alpha subunit
 9 14 23 42 --||----|||||----||-|-|-|--|||||||||||  43 [C]  COG0114 Fumarase
12 24 32 55 |-||||-|-||||||-|||||-|||-||||||||||||  59 [C]  COG0221 Inorganic pyrophosphatase
 9 16 24 48 --|--------||-||||-|--||||||||||||||||  50 [C]  COG0224 F0F1-type ATP synthase, gamma subunit
13 21 29 52 |-----|----|||||||||||||||||||||||||||  56 [C]  COG0240 Glycerol-3-phosphate dehydrogenase
 8 18 24 39 ||-||||||||---|-|||---|-|--||-|||-|||- 149 [C]  COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing
 9 19 26 42 |||||-|||||---|-||||--|-||-||-|||||-|- 115 [C]  COG0247 Fe-S oxidoreductase
10 19 27 43 --|||-|-|||||-|-||||--|||--||||||||||- 171 [C]  COG0277 FAD/FMN-containing dehydrogenases
 9 15 23 46 --||-----------|-|||-|||||||||||||||||  70 [C]  COG0280 Phosphotransacetylase
 9 19 29 47 --|||||-|||||--||||---||||-|||||||||||  69 [C]  COG0281 Malic enzyme
 9 15 20 43 --|------------|||||-||||||||-||-||-||  55 [C]  COG0282 Acetate kinase
 5 13 18 29 -||-|-||-|------||-----|---||-|||||||-  43 [C]  COG0348 Polyferredoxin
 9 16 24 48 --|--------||-||||-|--||||||||||||||||  50 [C]  COG0355 F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit)
 9 15 23 47 --|--------|--||||-|--||||||||||||||||  47 [C]  COG0356 F0F1-type ATP synthase, subunit a
 7 17 20 30 |||||||||||-|--|||-----|||--|-------|-  37 [C]  COG0371 Glycerol dehydrogenase and related enzymes
10 19 29 47 |-|||-|-|||||-|||||---|-||-|||||||||||  80 [C]  COG0372 Citrate synthase
 5  8  8 13 --|---||------|-|------|----|-----|---  21 [C]  COG0374 Ni,Fe-hydrogenase I large subunit
 8 16 23 38 --|||||-|||---|||||---|----|||--||||||  39 [C]  COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases
 7 13 14 18 |||--||-------||||-|---|---||---|-----  39 [C]  COG0426 Uncharacterized flavoproteins
 6  9 11 16 ---|--|----||----|-|--|----||------||-  19 [C]  COG0427 Acetyl-CoA hydrolase
 4 10 15 21 --||-||-|||---|------------||-|||-|-|-  73 [C]  COG0437 Fe-S-cluster-containing hydrogenase components 1
10 21 30 48 |||--|||||-||-|||||---||||-|||||||||||  75 [CE] COG0473 Isocitrate/isopropylmalate dehydrogenase
10 20 29 48 ||-||-|||||||-|-|||-|-|-|--|||||||||||  62 [C]  COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit
 9 15 25 48 ---||---|||||---|||-|-|-||||||||||-||| 122 [C]  COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes
14 27 37 65 |||||||-|||||||||||||||||||||||||||||| 357 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins
10 17 23 36 ---||-|-|||||-|||||---|-||-||--||-|||-  38 [C]  COG0538 Isocitrate dehydrogenases
10 20 25 38 |||-||||-|-||-||---|-|||||-||-|-||--||  67 [HC] COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases
12 20 27 46 ---||||--|||--||||||-||||||||||||--||-  52 [C]  COG0554 Glycerol kinase
 6  9 16 33 -----------||-----|-|-|-|--|||||||-|||  38 [C]  COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes
10 14 19 36 ---||----|-|||---||--||-||-||||||---|-  53 [C]  COG0578 Glycerol-3-phosphate dehydrogenase
12 19 25 44 ---|||--|-||||-||-||-||||||||-|||--||-  93 [C]  COG0584 Glycerophosphoryl diester phosphodiesterase
 9 14 21 35 --|||---||-||-|-|-|---|-||-||||||--||- 139 [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases
 9 13 19 31 ---|-------||||-|||-|-|----||-||||-|||  69 [C]  COG0633 Ferredoxin
14 28 37 65 ||||||||-|||||||||||||||||||||||||||||  77 [C]  COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K
10 21 27 39 |||||||||||||-||||-|--||---|||--||-||-  98 [C]  COG0644 Dehydrogenases (flavoproteins)
 8 16 23 38 --|||||-|||---|||||---|----|||--||||||  41 [C]  COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7
 5 10 10 15 |||-||-|-|-----|------|-----|---------  23 [C]  COG0650 Formate hydrogenlyase subunit 4
 8 16 21 33 |||||||-|||----||||---|-|--||-|-----||  69 [CP] COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit
 6 10 17 30 -----------||---|||---|-|--|||||||-||| 109 [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
12 18 25 38 ---||---|||||-||||||-||-||-||||-|-|||- 153 [C]  COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)
11 22 26 37 |||||||||||||-||||-|-|||||--|-|---|---  81 [C]  COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit
 6 13 13 19 |||--|||-|----|-||-----|----|-----|---  37 [C]  COG0680 Ni,Fe-hydrogenase maturation factor
 8 14 22 46 --|-----------||||-|--||||||||||||||||  62 [C]  COG0711 F0F1-type ATP synthase, subunit b
 8 15 23 47 -----------||-||||-|--||||||||||||||||  48 [C]  COG0712 F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)
 7 13 18 32 --|||-----|---|-|||---|----|||--||||||  34 [C]  COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)
 7 16 21 32 |||---||---||---||-|-|-|||-||||||-|---  71 [C]  COG0716 Flavodoxins
 9 17 24 36 --|||---|||||-|-|||---|||--|-||-||||||  55 [C]  COG0723 Rieske Fe-S protein
 8 17 19 23 |||||||||||||--|||-|---|----------|---  30 [C]  COG0731 Fe-S oxidoreductases
10 22 31 50 |||||||||||---||||||--||||-||||||||||- 161 [C]  COG0778 Nitroreductase
12 20 27 53 --||--|----||||||--||||||||||-||||||||  60 [C]  COG0822 NifU homolog involved in Fe-S cluster formation
 7 14 21 35 --|||-|-|||---|-|||---|----|||--||||||  38 [C]  COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A)
 7 14 20 34 --|||-|--||---|-|||---|----|||--||||||  40 [C]  COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J)
 9 12 18 33 ---|----||||--|-|||---|-|--|||--|--|||  60 [C]  COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1
 8 16 23 38 --|||||-|||---|||||---|----|||--||||||  40 [C]  COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit
 7 14 21 35 --|||-|-|||---|-|||---|----|||--||||||  38 [C]  COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H)
 7 14 21 35 --|||-|-|||---|-|||---|----|||--||||||  37 [C]  COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N)
 6 12 17 31 --|||---------|-|||---|----|||--||||||  40 [C]  COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M)
 8 16 24 42 --|||||-|||---|-|||---|-|--||||-||||||  65 [CP] COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit
10 22 31 50 |||||--||||||-|-||||--|||||||-|||||||| 358 [C]  COG1012 NAD-dependent aldehyde dehydrogenases
11 22 26 37 |||||||||||||-||||-|-|||||--|-|---|---  79 [C]  COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit
10 22 27 38 |||||||||||---||||-|-|||||--|-|-|-|||-  89 [C]  COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit
 6 10 13 19 -----------||-|---|---|-|--||||-|-|-|-  19 [C]  COG1017 Hemoglobin-like flavoprotein
 7 10 15 28 ---|-------||-----||--|-|--||||-||-||-  78 [C]  COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1
 1  5  5  5 |||---||------------------------------  12 [C]  COG1029 Formylmethanofuran dehydrogenase subunit B
 3  8  9 10 -|||-||||-|----|----------------------  10 [C]  COG1031 Uncharacterized Fe-S oxidoreductase
 9 18 23 29 |||-|||||||----|||||--||||-||-|-----|-  87 [C]  COG1032 Fe-S oxidoreductase
 7 11 16 29 --------------|||||---||---|||--||||||  30 [C]  COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)
 3  8  8  8 |||---||--------||------------------|-  22 [C]  COG1035 Coenzyme F420-reducing hydrogenase, beta subunit
 1  5  5  5 |||---||------------------------------   8 [C]  COG1036 Archaeal flavoproteins
 4  6  7 15 -----------||---------||||----------|-  16 [C]  COG1038 Pyruvate carboxylase
 4 12 15 23 -|||||||||------|----------||-|--|--|-  47 [C]  COG1042 Acyl-CoA synthetase (NDP forming)
 8 14 23 38 --|||---|||||-|---|---||||-||||-||-|||  48 [C]  COG1048 Aconitase A
 2  6 11 18 ----------------||---------||||||||-|-  18 [C]  COG1049 Aconitase B
 9 16 24 40 ----||--|||||-|-||-|-|-|||-||-|||||||-  92 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases
12 23 33 53 ||-||-|||||||-|||||||-||||-|||||||||||  83 [C]  COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit
 6 10 14 25 ---------|-||---||----|-|--||--|||-||-  42 [C]  COG1062 Zn-dependent alcohol dehydrogenases, class III
 3  4  4 13 -----------|------------|---|-------|-  17 [C]  COG1069 Ribulose kinase
10 16 21 35 ---||---||||||--|||-|-|-||||----|--|||  58 [C]  COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
 7 11 13 19 --|--||-|--||--|------||-|--|-||------  21 [C]  COG1085 Galactose-1-phosphate uridylyltransferase
 6 11 16 23 |--||-|-|||-------||----||--|--||||---  24 [C]  COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain
 4  6  8 14 --------|-|-----------|-|--||---|---|-  18 [C]  COG1140 Nitrate reductase beta subunit
 6 11 13 19 |--|-||-|-|----|||----||||------------  27 [C]  COG1141 Ferredoxin
 4 10 10 15 |||--|||-------|||----------|---------  45 [C]  COG1142 Fe-S-cluster-containing hydrogenase components 2
 8 18 25 40 |||||||-|||---|||||---|----|||--||||||  52 [C]  COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)
 5 11 12 15 |||-||||||----||------------------|---  22 [C]  COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit
 8 19 26 38 |||-|||||||----|||||---||--||||||||-|- 184 [C]  COG1145 Ferredoxin
 8 19 25 38 ||||||||||-----||||---||---||||-|-||||  84 [C]  COG1146 Ferredoxin
 4  8  8  8 |||---||-|----||----------------------  13 [C]  COG1148 Heterodisulfide reductase, subunit A and related polyferredoxins
 2  7  7  8 |||--|||-------|----------------------  16 [C]  COG1149 MinD superfamily P-loop ATPase containing an inserted ferredoxin domain
 3  7  7  7 |||---||-|----|-----------------------  11 [C]  COG1150 Heterodisulfide reductase, subunit C
 5 10 10 14 |||--|||-------|---|---|----|---------  19 [C]  COG1151 6Fe-6S prismane cluster-containing protein
 1  5  5  5 |||---||------------------------------  10 [C]  COG1152 CO dehydrogenase/acetyl-CoA synthase alpha subunit
 1  5  5  5 |||---||------------------------------   9 [C]  COG1153 Formylmethanofuran dehydrogenase subunit D
 9 17 19 24 ||||||||||||||----||||---|------------  31 [C]  COG1155 Archaeal/vacuolar-type H+-ATPase subunit A
 9 17 19 24 ||||||||||||||----||||---|------------  26 [C]  COG1156 Archaeal/vacuolar-type H+-ATPase subunit B
 8 11 12 16 -|----|----|||-|--||---|||----|-------  17 [C]  COG1227 Inorganic pyrophosphatase/exopolyphosphatase
 1  5  5  5 |||---||------------------------------   7 [C]  COG1229 Formylmethanofuran dehydrogenase subunit A
12 23 33 56 |||||-|||||||-|||||||-|-||||||||||-||| 162 [C]  COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
 5  8 10 19 --|-----------|-------|||--||---|--||-  24 [C]  COG1251 NAD(P)H-nitrite reductase
 8 12 16 29 ---|-----|-||---|||---|-||-||-|||---|-  55 [C]  COG1252 NADH dehydrogenase, FAD-containing subunit
 9 16 22 34 -||-|||-|||----||-|--|||||-||-|||---|-  42 [C]  COG1254 Acylphosphatases
 9 17 19 24 ||||||||||||||----||||---|------------  26 [C]  COG1269 Archaeal/vacuolar-type H+-ATPase subunit I
 7 14 20 36 --|||-|-------|-||--|-|-||-||-|||-||||  52 [C]  COG1271 Cytochrome bd-type quinol oxidase, subunit 1
 6  7  7 13 ----||---|----------|||---------|-----  13 [C]  COG1274 Phosphoenolpyruvate carboxykinase (GTP)
 3  6 12 24 ----------------||----|----||-||||-|||  26 [C]  COG1282 NAD/NADP transhydrogenase beta subunit
 9 14 21 33 ---||---||||--|-|||---|-|--|-||-||||||  45 [C]  COG1290 Cytochrome b subunit of the bc complex
 7 12 18 33 --||----------|-||--|-|-||-||-|||-||||  46 [C]  COG1294 Cytochrome bd-type quinol oxidase, subunit 2
11 17 22 36 --||-|----|---|-|-|||||||--||||-|-||||  69 [C]  COG1301 Na+/H+-dicarboxylate symporters
 9 20 28 48 |||||||||||||---|||--||-||-||-||-|-|||  71 [C]  COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
 6  8 11 18 --------|||-------|--||-|--||---|---|-  38 [C]  COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs
 2  3  6  9 --------------------|------||-||-|----   9 [C]  COG1347 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD
 8 16 17 21 |||||||||-||||----||||----------------  21 [C]  COG1390 Archaeal/vacuolar-type H+-ATPase subunit E
 9 17 19 24 ||||||||||||||----||||---|------------  25 [C]  COG1394 Archaeal/vacuolar-type H+-ATPase subunit D
 8 13 14 19 |-||-------|||--||--||--|--||-------|-  54 [C]  COG1413 FOG: HEAT repeat
 8 16 18 20 ||||||||||||||----||-|---|------------  20 [C]  COG1436 Archaeal/vacuolar-type H+-ATPase subunit F
 9 18 23 36 |-|||||--||||-||---|--||||-||-|||---|-  73 [C]  COG1454 Alcohol dehydrogenase, class IV
 1  5  5  5 |||---||------------------------------   6 [C]  COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein)
 5 12 17 31 |||-|-|-||------------|-|--||-|||-|||-  32 [C]  COG1526 Uncharacterized protein required for formate dehydrogenase activity
 7 15 15 18 |||||||||--|||----||-----|------------  18 [C]  COG1527 Archaeal/vacuolar-type H+-ATPase subunit C
 7  9 13 19 --------|||---|---|--||-|--||---|--||-  60 [C]  COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs
 7 13 13 13 |||--|||-|-----||--|---||---------|---  28 [C]  COG1592 Rubrerythrin
 5 11 15 25 |-|---|---------|||----|||-||-|-|--||-  31 [C]  COG1600 Uncharacterized Fe-S protein
 1  5  5  5 |||---||------------------------------   7 [C]  COG1614 CO dehydrogenase/acetyl-CoA synthase beta subunit
 6 11 15 24 ---|--||-|--------|--|--|--||-|||||-|-  34 [C]  COG1620 L-lactate permease
 9 13 19 34 ---|--|-||||--|-|||---|-|--|||--|--|||  60 [C]  COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2
 4  9  9 10 |||--|-|--------|||----|--------------  12 [C]  COG1625 Fe-S oxidoreductase, related to NifB/MoaA family
 6 13 16 21 ||||-||-|||----|--|----|||---|-----|--  26 [CP] COG1668 ABC-type Na+ efflux pump, permease component
 2  3  6  9 --------------------|------||-||-|----   9 [C]  COG1726 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA
 5  7  7 12 --|---|-------|-|------|----|-----|---  21 [C]  COG1740 Ni,Fe-hydrogenase I small subunit
 6 10 12 20 ---|-|----|--------|-|-||---|-||-||---  43 [C]  COG1757 Na+/H+ antiporter
 8 14 17 22 ||---||--------|||-|-|||---|||--||-|--  33 [C]  COG1773 Rubredoxin
 5  8 11 18 ----|-|-||--------|---|----||---|--||-  56 [C]  COG1804 Predicted acyl-CoA transferases/carnitine dehydratase
 3  6  9 12 ----------------||--|------||-||-|--|-  12 [C]  COG1805 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB
 7 12 14 19 |||----|---|-----||---|||--||-|-----|-  38 [GC] COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
 6 14 18 25 |||--||||-----||-------||--||||-||--|-  38 [C]  COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain
 9 12 18 33 ---|----||||--|-|||---|-|--|||--|--|||  56 [C]  COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3
 6  8 11 21 ----------||------||----|--||-||--|-|-  21 [C]  COG1866 Phosphoenolpyruvate carboxykinase (ATP)
 1  5  5  5 |||---||------------------------------   7 [C]  COG1880 CO dehydrogenase/acetyl-CoA synthase epsilon subunit
 4  7 10 18 |-----|------------|---|||--|-|||-----  34 [C]  COG1882 Pyruvate-formate lyase
 6  7  9 10 -----||--------|---|-|---|--|-||------  14 [C]  COG1883 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit
 8 11 16 27 |-----------|-|||||---|----|||--||-|||  33 [C]  COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit
10 18 23 37 --|||-|--|-||--||-||--|||||||||-|--||-  95 [C]  COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family
 8 11 16 27 |-----------|-|||||---|----|||--||-|||  34 [C]  COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit
 1  5  5  5 |||---||------------------------------   9 [C]  COG1908 Coenzyme F420-reducing hydrogenase, delta subunit
 1  5  5  5 |||---||------------------------------   5 [C]  COG1927 Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin dehydrogenase
 2  8  8  9 |||--|||--------||--------------------  16 [C]  COG1941 Coenzyme F420-reducing hydrogenase, gamma subunit
 6 14 18 25 |||--||||-----||-------||--||||-||--|-  37 [C]  COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain
 2  3  3  8 --------------|-------------|-----|---   9 [C]  COG1969 Ni,Fe-hydrogenase I cytochrome b subunit
 5  6  8 14 ---------------||--|---||---|-||------  17 [C]  COG1979 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family
 8 14 21 38 ---||-|-|-|||-----|-|-|-|--||||-||||||  40 [C]  COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit
 6 11 14 24 --|---|---------|||---|-|--|--|-|||||-  78 [C]  COG2010 Cytochrome c, mono- and diheme variants
 9 15 21 33 ---||-|-|||||--|--||--|||--|||--||-||-  57 [C]  COG2025 Electron transfer flavoprotein, alpha subunit
 4  8  8  9 |||--||--------|-----|-|--------------  10 [C]  COG2033 Desulfoferrodoxin
 1  5  5  5 |||---||------------------------------   8 [C]  COG2037 Formylmethanofuran:tetrahydromethanopterin formyltransferase
 5 10 10 10 |||---||-|----|-||----------------|---  17 [C]  COG2048 Heterodisulfide reductase, subunit B
 4  9 11 19 ||---|-|--------------|||--||--|----|-  32 [C]  COG2055 Malate/L-lactate dehydrogenases
 1  5  5  5 |||---||------------------------------   6 [C]  COG2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein)
 6  8 12 19 --------|||-------|--||-|--||---|--||-  49 [C]  COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs
 9 15 21 33 ---||-|-|||||--|--||--|||--|||--||-||-  54 [C]  COG2086 Electron transfer flavoprotein, beta subunit
 7 15 19 33 ||||--||-|------|-|---|-||||||--|--||- 165 [C]  COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
 5  8 14 26 ----|-|---|-------|---|----||||-||-|||  26 [C]  COG2142 Succinate dehydrogenase, hydrophobic anchor subunit
 5  7  9 15 ------|-|-|-----------|-|--||---|---|-  21 [C]  COG2180 Nitrate reductase delta subunit
 5  7  8 14 ------|-|-------------|-|--||---|---|-  22 [C]  COG2181 Nitrate reductase gamma subunit
 2  6  6  8 |-|-|||-----------|-------------------  12 [C]  COG2191 Formylmethanofuran dehydrogenase subunit E
 2  3  6  9 --------------------|------||-||-|----  10 [C]  COG2209 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE
 1  5  5  5 |||---||------------------------------  10 [C]  COG2218 Formylmethanofuran dehydrogenase subunit C
 4  8  8  8 |||---|||--------------|----|---------  14 [C]  COG2221 Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits
 6  9 12 22 ---------|-||-----|---|-|--||-|-|--||-  26 [C]  COG2224 Isocitrate lyase
 6  8 12 22 --------||-|------|---|-|--||-|-|--||-  26 [C]  COG2225 Malate synthase
 5  8 12 20 ----------------|||---|--|-||-||||-|--  20 [C]  COG2352 Phosphoenolpyruvate carboxylase
 4  8  9 13 -||-|||-|-|------------|----|---------  33 [C]  COG2414 Aldehyde:ferredoxin oxidoreductase
 7  7  9 11 -----|---||-|--||-------|----------||-  11 [C]  COG2421 Predicted acetamidase/formamidase
 5  6  8 13 ----|---|||----|---|--------|-------|-  21 [C]  COG2440 Ferredoxin-like protein
 2  3  4  5 -----||--||---------------------------   5 [C]  COG2441 Predicted butyrate kinase
 3  5 11 21 ------------------|---|----|||||||-||-  21 [C]  COG2609 Pyruvate dehydrogenase complex, dehydrogenase (E1) component
 5  9  9 10 |||----|--------||-|---|------------|-  44 [C]  COG2710 Nitrogenase molybdenum-iron protein, alpha and beta chains
 2  8  8 10 |||||||-----------|-------------------  10 [C]  COG2811 Archaeal/vacuolar-type H+-ATPase subunit H
 2  4  6 10 ----------------------|----|-||--||---  10 [C]  COG2838 Monomeric isocitrate dehydrogenase
 3  5  7 10 ----------------------|-||-|-|---||---  12 [C]  COG2851 H+/citrate symporter
 4  8 13 21 -----------||-|---------|--|-||-||||||  24 [C]  COG2857 Cytochrome c1
 2  5  9 12 ------------------|--------||-|||||-|-  21 [C]  COG2863 Cytochrome c553
 3  7 10 15 --|---|-------|------------||-|||-|-|-  20 [C]  COG2864 Cytochrome b subunit of formate dehydrogenase
 2  3  6  9 --------------------|------||-||-|----   9 [C]  COG2869 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC
 2  3  6  9 --------------------|------||-||-|----   9 [C]  COG2871 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF
 4  5 10 17 --|------------|---|-------|||||||----  17 [C]  COG2878 Predicted NADH:ubiquinone oxidoreductase, subunit RnfB
 1  2  7 14 ---------------------------|||||||----  14 [CO] COG2924 Fe-S cluster protector protein
 1  4  7 13 ---------------------------|--|-|||||-  18 [C]  COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit
 1  3  6 12 ---------------------------||-||--|-|-  26 [C]  COG3005 Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit
 2  2  4 10 ----------------------|-----|-||------  10 [C]  COG3029 Fumarate reductase subunit C
 2  4 11 18 -----------------|---------|||||||-|||  37 [C]  COG3038 Cytochrome B561
 1  3  6 12 ---------------------------||-||--|-|-  12 [C]  COG3043 Nitrate reductase cytochrome c-type subunit
 3  3  5  9 -------------------|-----|--|-||------  10 [C]  COG3051 Citrate lyase, alpha subunit
 3  3  5  9 -------------------|-----|--|-||------  10 [C]  COG3052 Citrate lyase, gamma subunit
 3  3  5  9 -------------------|-----|--|-||------  10 [C]  COG3053 Citrate lyase synthetase
 1  1  3  7 ----------------------------|-||------  13 [C]  COG3069 C4-dicarboxylate transporter
 2  2  4 10 ----------------------|-----|-||------  10 [C]  COG3080 Fumarate reductase subunit D
 2  4  7 17 ------------------------|--|||--|--||-  20 [C]  COG3125 Heme/copper-type cytochrome/quinol oxidase, subunit 4
 3  4  4  6 -------------|------|--------|-------|  19 [C]  COG3202 ATP/ADP translocase
 1  2  3  4 ---------------------------|-|---|----   4 [C]  COG3241 Azurin
 1  3  5  6 ---------------------------|--|-||-|--  10 [C]  COG3245 Cytochrome c5
 2  5  5  5 -----------------|---------|----|-|-|-   7 [C]  COG3258 Cytochrome c
 2  8  8  9 |||--|||--------||--------------------  16 [C]  COG3259 Coenzyme F420-reducing hydrogenase, alpha subunit
 4  9  9 14 |||-||-|-|------------|-----|---------  20 [C]  COG3260 Ni,Fe-hydrogenase III small subunit
 4  9  9 13 |||-||-|-|------------|-----|---------  19 [C]  COG3261 Ni,Fe-hydrogenase III large subunit
 3  4  4  8 --|--|----------------|-----|---------  12 [C]  COG3262 Ni,Fe-hydrogenase III component G
 3  6 12 23 ----------------||----|----||-||||-|||  36 [C]  COG3288 NAD/NADP transhydrogenase alpha subunit
 1  2  5 11 ---------------------------||-||-|----  11 [C]  COG3312 F0F1-type ATP synthase, subunit I
 7  8  8  8 ---|----------|||||-----|-------|-----   9 [C]  COG3411 Ferredoxin
 3  4  4  5 ---------------|--|----||-------------   7 [C]  COG3426 Butyrate kinase
 2  3  5  9 -----------||----------------------|||  21 [C]  COG3474 Cytochrome c2
 1  2  3  5 ---------------------------|--|-----|-   5 [C]  COG3488 Predicted thiol oxidoreductase
 3  3  5  7 -------------------|----||--|-|-------   8 [C]  COG3493 Na+/citrate symporter
 3  4  6  7 -----||--------------|------|-||------  10 [C]  COG3630 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit
 1  3  4  5 ------------------------------|-||-|--   6 [C]  COG3658 Cytochrome b
 1  1  3  7 -----------------------------------|||   7 [C]  COG3761 NADH:ubiquinone oxidoreductase 17.2 kD subunit
 1  1  3  7 ----------------------------|-||------   8 [C]  COG3783 Soluble cytochrome b562
 3  5  5  8 --||------------||------------------|-  21 [C]  COG3794 Plastocyanin
 5  5  6  9 --|-----|------|---|---------------||-  10 [C]  COG3808 Inorganic pyrophosphatase
 1  3  3  6 ---------------------------|-----|--|-   6 [C]  COG3909 Cytochrome c556
 1  2  3  7 ----------------------------|-|-----|-   7 [C]  COG3954 Phosphoribulokinase
 1  3  3  3 ||-----|------------------------------   3 [C]  COG4074 H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase
 2  4  5  9 ----------------|----------||---|---|-   9 [C]  COG4117 Thiosulfate reductase cytochrome B subunit (membrane anchoring protein)
 3  4  5  5 -----------||-|------------|-|--------   5 [C]  COG4229 Predicted enolase-phosphatase
 1  3  7 15 ---------------------------||--|||-||-  15 [C]  COG4230 Delta 1-pyrroline-5-carboxylate dehydrogenase
 4  9 11 13 |-|-|||-||-------------|--------|--||-  20 [C]  COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits
 2  5 10 17 --------------------|------|||||||||--  19 [OC] COG4232 Thiol:disulfide interchange protein
 2  3  4  8 --------------------|-------|------||-   8 [OC] COG4233 Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis
 4  4  4  7 ----|----|------------|-----|---------   7 [C]  COG4237 Hydrogenase 4 membrane component (E)
 1  3  3  4 ---------------------------|----|---|-   5 [C]  COG4263 Nitrous oxide reductase
 1  3  3  4 ---------------------------|----|---|-   8 [C]  COG4313 Protein involved in meta-pathway of phenol degradation
 1  3  4  6 ---------------------------|----||--|-   6 [C]  COG4314 Predicted lipoprotein involved in nitrous oxide reduction
 2  3  3  3 ----------------||------------------|-   6 [C]  COG4451 Ribulose bisphosphate carboxylase small subunit
 1  2  3  4 ---------------------------|--|-----|-   4 [C]  COG4459 Periplasmic nitrate reductase system, NapE component
 5  6  6  6 ---------------|--|--|-||----|--------   6 [CP] COG4555 ABC-type Na+ transport system, ATPase component
 4  5  5  8 ----------------||-|----|---|---------  10 [QC] COG4576 Carbon dioxide concentrating mechanism/carboxysome shell protein
 4  5  5  8 ----------------||-|----|---|---------  31 [QC] COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein
 3  4  6 10 --|----------------------|--|-||----|-  10 [CH] COG4635 Flavodoxin
 2  3  3  3 --------------|------------|----|-----   5 [C]  COG4654 Cytochrome c551/c552
 6  6  9 16 --|------------|---|-|--|--||-||------  17 [C]  COG4656 Predicted NADH:ubiquinone oxidoreductase, subunit RnfC
 4  4  7 13 --|------------|---|-------||-||------  13 [C]  COG4657 Predicted NADH:ubiquinone oxidoreductase, subunit RnfA
 5  5  8 14 --|------------|---|-|-----||-||------  14 [C]  COG4658 Predicted NADH:ubiquinone oxidoreductase, subunit RnfD
 4  4  7 13 --|------------|---|-------||-||------  13 [C]  COG4659 Predicted NADH:ubiquinone oxidoreductase, subunit RnfG
 4  4  7 13 --|------------|---|-------||-||------  13 [C]  COG4660 Predicted NADH:ubiquinone oxidoreductase, subunit RnfE
 1  1  2  5 ------------------------||------------   5 [C]  COG4781 Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase
 2  5  5  5 |-|---|---------||--------------------   6 [C]  COG4802 Ferredoxin-thioredoxin reductase, catalytic subunit
 2  3  7 16 ------------------------||--|-||---||-  16 [CO] COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components
 4  5  9 21 -------------------|--|-||--|-||---||-  24 [CO] COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components
 4  6  8 14 --------|-|-----------|-|--||---|---|-  21 [C]  COG5013 Nitrate reductase alpha subunit
 7 12 15 15 |||--||-------||---|-|---|-||-||--|---  19 [C]  COG5016 Pyruvate/oxaloacetate carboxyltransferase
 2  3  3  3 -----------|||------------------------   3 [C]  COG5127 Vacuolar H+-ATPase V1 sector, subunit C
 2  3  3  3 -----------|||------------------------   3 [C]  COG5231 Vacuolar H+-ATPase V1 sector, subunit H
 2  3  3  3 -----------|||------------------------  12 [CI] COG5274 Cytochrome b involved in lipid metabolism
 2  3  3  6 ---|--|---------------------|---------   7 [C]  COG5557 Polysulphide reductase