(order) Burkholderiales - 1 genome Functional categories Fun All J A K L B D Y V T M N Z W U O C G E F H I P Q R S COGs 2,017 136 2 80 99 1 21 -  18 67 113 68 -  1 95 93 131 103 172 66 122 61 104 49 254 322 proteins 4,099 175 2 392 270 2 29 -  49 279 254 145 -  1 206 165 288 260 475 84 166 197 246 172 594 406 Distribution of COGs by number of proteins proteins 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 27 30 36 38 63 76 COGs 1380 324 119 53 41 18 16 13 3 3 6 2 5 6 3 3 4 2 3 1 2 2 1 1 1 1 1 1 1 1

++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
||------||------|-||||----||||||||||||----|||||-||||||||--||||||-- 76 [K] COG0583 Transcriptional regulator
||||||||||||||||||||||||||||||||||||||-||||||||||||||||||||||||||| 63 [GEPR] COG0477 Permeases of the major facilitator superfamily
--|-||--|----||---||||----|||--|||||-|||--|||||-|||--|||---|||||-- 38 [L] COG2801 Transposase and inactivated derivatives
--|||||||-||||||||||||||--||||||||||||----|||||||||||||||||||||||| 36 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
|-||----|----||-||||||||-|||||||||||||----|||||-|||||||||||||||||| 30 [T] COG0642 Signal transduction histidine kinase
----------------||||||||--||||||||||||----|||||-|||||||||||||||||| 27 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
|-||---||--|----||||||----|||||||||||||---|||||-||||||||--||||||-- 24 [K] COG1309 Transcriptional regulator
--||--|||--------|||-|--||----|----|||----|||||-||--|--||||||-||-- 23 [NT] COG0840 Methyl-accepting chemotaxis protein
|-|||||||-|||||||||||||||-|||-||-|||||----|||||||||||||||||||||||| 22 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily
----------------||||-|--|-|||||---||||----|||||-||--|--|---|||||-- 22 [T] COG2199 FOG: GGDEF domain
----------------|-|||---------------------|||||-|||||||||||||||||| 21 [MU] COG1538 Outer membrane protein
|-||----|-----|-||||-|||-||||||----|||----|||||-||--|--|--||||||-- 21 [T] COG2202 FOG: PAS/PAC domain
--||||--|-|||||||-||||---|||||||-||||||||||||||-|||||||||||||||||| 20 [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) 
-|-|----|-|||----|||||----|------|---|----|||||--|-----|--|||||--- 19 [E] COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
|||||||||||||----|-|||----||||||||||||----|||||-||--||||---|||||-- 19 [K] COG1846 Transcriptional regulators
--|---------------------------|----||-----|||||--|-----|------|--- 19 [M] COG3209 Rhs family protein
----------------||||||--|||---|-||||||----|||||-|||||||||||||||||| 18 [M] COG0845 Membrane-fusion protein
------------------------------------------|||||||-||-|||---------- 18 [M] COG3203 Outer membrane protein (porin)
-------------||---||------------||--------|||||-||||||||---||||||| 17 [O] COG0625 Glutathione S-transferase
|-||--|||----|||-|||-|--||-||-|----|||----|||||-|||||--|||||||||-- 17 [T] COG0784 FOG: CheY-like receiver
-----------------||||-----|||-||-|||||----|||||-||||||||--||||||-- 17 [K] COG2207 AraC-type DNA-binding domain-containing proteins
--|---------------||-|----||-----|---------------------|---|-|||-- 17 [L] COG3293 Transposase and inactivated derivatives
---|||--|-||||-----|||----|||||---|-||----|||||-||---|||---|||||-- 16 [I] COG1960 Acyl-CoA dehydrogenases
-----|--------------||----|||--|||||-|----|||||-|||----|---|||||-- 16 [L] COG2963 Transposase and inactivated derivatives
--||||---------------------||-------------|-----|----|||---||-|--- 16 [L] COG3039 Transposase and inactivated derivatives, IS5 family
||||||---||||||-|-||||----|||||||||||||---|||||-||-|-|||||||||||-| 15 [C] COG1012 NAD-dependent aldehyde dehydrogenases
-------------||----|------||||-||||||-----|||||-||-----|--||-||--- 15 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins
----------------||||||||------||||||||----|||||-|||||--|--|---||-- 15 [NU] COG2165 Type II secretory pathway, pseudopilin PulG
|||||||||--||---||||||||--||||||||||||||--|||||-|||||||||||||||||| 14 [L] COG0582 Integrase
--|-----|-|-|----||||||||-||||||||||||----|||||-||||-||||||||||||| 14 [ET] COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain
---|||--|-|||||-|--|||----|||||-|||-||----|||||-||--|--|---||||||| 14 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase
|-|-------|-----||-|||--|-|||-||||||||----|||||-||||||||---||||||| 14 [K] COG1396 Predicted transcriptional regulators
----------------|-|||---------------------|||||-||||||||||||||||-- 14 [P] COG1629 Outer membrane receptor proteins, mostly Fe transport
---------||-------||-|----||||||--||||----|||||-||-----|---|||||-- 14 [K] COG2771 DNA-binding HTH domain-containing proteins
|||||||||||||||||||||||||-||||||||||||----|||||||||||||||||||||||| 13 [QR] COG0500 SAM-dependent methyltransferases
|||||||||||||--------|----|||-|-----||----|||||-||||-|||---|||||-- 13 [K] COG1522 Transcriptional regulators
------------------||-|----|||-||||||||----|||||-||||||||---|||||-- 13 [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
----------------|-||-|---||||||----|||----|||||-||--|--|---||||||| 13 [T] COG2200 FOG: EAL domain
-------------------|-----------------------||||-||-----|---|--|--- 13 [S] COG3501 Uncharacterized protein conserved in bacteria
|||||||||-||||||||||||||--|||||||||||||---|||||-||||||||||||||||-| 12 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
--|-----|-|-|----|||||||--|---||||||||----|||||-|||--||||||||||||| 12 [E] COG0765 ABC-type amino acid transport system, permease component
||||||||||||||||||||||----||||||||||||----||||||||||||||||||||||-- 11 [R] COG0491 Zn-dependent hydrolases, including glyoxylases
|||||||||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||| 11 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins
--|||||||-|||||-|-||-|||-|||||||||-|||----|||||-||||||||||||||||-- 11 [E] COG0665 Glycine/D-amino acid oxidases (deaminating)
--|-------------||||||---|----|---|-||----|||||-|||||||||||||||||| 11 [V] COG0841 Cation/multidrug efflux pump
------------------|||----------------------|||---|||||||--|----|-- 11 [U] COG3210 Large exoproteins involved in heme utilization or adhesion
--|--|--|--|------||-|----|------|---|-----||-|-------||----|-|--- 11 [L] COG3335 Transposase and inactivated derivatives
---|--||--|||||-||||||----||||||||||||----||||||||||||||||||||||-- 10 [J] COG0251 Putative translation initiation inhibitor, yjgF family
|-||||--|-|||||---||-|||--||||-||-||||----|||||-||||||||--|||||||| 10 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II
---------------------------------------------|---|-----|---------- 10 [S] COG4253 Uncharacterized protein conserved in bacteria
|||||||||||||||-|||||||||-||||||||||||----|||||-||||||||||||||||||  9 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase
|-|-||--|||||----||--|----|---------||----|||||-|||||--|--||||||--  9 [E] COG1280 Putative threonine efflux protein
-----------------|||||--|-||||||--||||----|||||-||||||||---|||||--  9 [K] COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
||||||||||||-||-||||||---|||||||-|||||----|||||-||||||||||||||||--  8 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases
|||||||||--|-|||||||||||||----||||||||----|||||-||-|||||||||||||||  8 [R] COG0457 FOG: TPR repeat
|-||||--|-|||||||||||||||-||||||||||||----||||||||||||||||||||||||  8 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
|||||||||||||-|-|-||-|----||||-|||||||----|||||-||||-|||---|||||||  8 [T] COG0589 Universal stress protein UspA and related nucleotide-binding proteins
-------------||---||-|----|||-----|-||----|||||-||-|||||---|||||||  8 [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
----------------||||----||----||||-|||----||||||||||||||||||||||||  8 [M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)
--|-----|-|-|----|||||||--|---||||||||----|||||-|||--|||||||||||||  8 [E] COG1126 ABC-type polar amino acid transport system, ATPase component
----||||--|||||--|-|||----|||||-||||||----|||||-||-|---|---|||||--  8 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
||-|--|||-|||---|--|-|||||||||||||||||----|||||-||--||||||||||||||  8 [K] COG1475 Predicted transcriptional regulators
||||||--|--||-----||||----|||-||--||||----|||||-||-||--|--|||-||--  8 [K] COG1733 Predicted transcriptional regulators
--||||--|--|-||--|-|||----|||-|||-||||-|--|||||-||--|--|---|||||--  8 [C] COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family
----------------|---|-||||-----------|----|||||-||-|||||||||||||||  8 [T] COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
------------------|||----------------------|||---|||||||--|----|--  8 [U] COG2831 Hemolysin activation/secretion protein
--|----------||-||||||||||||||||||||||||||||||||||||||||||||||||||  7 [IQ] COG0236 Acyl carrier protein
--||||--|-|||||-|-||||----|||||-----||----|||||-||||||||||||||||--  7 [C] COG0277 FAD/FMN-containing dehydrogenases
|-||||--|-|||||||-||-|-----||--|--||||----|||||-||-||--||-||||||--  7 [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases
-|------|-|||----|||||----|------|---|----|||||--|-----|--|||||---  7 [E] COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
||||||||||||||||||||||---||||||||||||||||||||||-||||||||||||||||||  7 [M] COG0463 Glycosyltransferases involved in cell wall biogenesis
-|------|-|||----|||||----|------|---|----|||||--|-----|--|||||---  7 [E] COG0559 Branched-chain amino acid ABC-type transport system, permease components
|-||||--|-||-||||-||||---|||||||||||||----|||||||||||||||||||-||||  7 [P] COG0607 Rhodanese-related sulfurtransferase
-|--|||||||||||-||--||-|--||||||||||||----||||||||||||||||||||||||  7 [E] COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases
--|--|--|--|-||--|||-|--|-|||||||-||-|----|||||-||--|--|---||-||--  7 [I] COG0657 Esterase/lipase
|||||||||||||---||||||----|--|||--||||----|||||-||||||||||||||||--  7 [R] COG0730 Predicted permeases
--|-||----|||||---||------||||-||||-||----|||-|--|--|||||||||||---  7 [R] COG1064 Zn-dependent alcohol dehydrogenases
---|------------||---|----|||-------||----|||||-||||---|--||||||--  7 [K] COG1414 Transcriptional regulator
----|------|-----|--||----|||-|||-||||----|||||-||---|||---|||||--  7 [K] COG1802 Transcriptional regulators
--||-|-----|------||-|---------------|----|------------|----|-----  7 [L] COG3385 FOG: Transposase and inactivated derivatives
-|------|-|||----|||||----|------|---|----|||||--|-----|--|||||---  7 [E] COG4177 ABC-type branched-chain amino acid transport system, permease component
------------------|------------------------------------|------|---  7 [L] COG5659 FOG: Transposase
||||||||||||||||--|-||---||||||||-||||----|||||-|||----|||-|||||||  6 [I] COG0183 Acetyl-CoA acetyltransferase
|-||--|||--||||---||||----||||||||||||----|||||-||||||||--||||||--  6 [E] COG0346 Lactoylglutathione lyase and related lyases
-|------|-|||----|||||-----------|--------|||||--|-----|--|||||---  6 [E] COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
|||||||||||||||-||||||--|||||-||||||-|-||||||||-||-|---|---|||||--  6 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases
|||||||||||||||--|||-|----||||||||||||----|||||-|||||--|---|||||--  6 [G] COG0524 Sugar kinases, ribokinase family
--||||----||-||-|--|-|----||||-|--||||----|||||-||-||--|---|||||--  6 [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases
|||||||||||||---||||||----|||||||-||||----|||||-||-|||||--||||||--  6 [K] COG0640 Predicted transcriptional regulators
|-||||||-|||-||-||||-|----|---||||||||----|||||-||-|---|||||||||--  6 [R] COG0673 Predicted dehydrogenases and related proteins
-||-----||---||--|||||||--|---|--||-||----||||--||||---|---|||||--  6 [P] COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components
|||||--||||||---||||||----||||||||||||----|||||-||||||||||||||||--  6 [C] COG0778 Nitroreductase
--|-----|-------|-||||----||||||||||||----|||||-||||||||||||||||||  6 [K] COG0789 Predicted transcriptional regulators
---|------------||--||----|||||||-||||----||||||||||||||---|||||||  6 [K] COG1278 Cold shock proteins
----||--|-|--|||-||||-||--|---||||||||||--||||||||||||||||-|||||||  6 [I] COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes
-----------------|--||----|||-||||||||-|--|||||-|||||--|---|||||--  6 [K] COG1609 Transcriptional regulators
-----------------|--------|---||||||||-|--|||||-||||-|||---|||||--  6 [K] COG1737 Transcriptional regulators
--|-----|---------||-|----||||------||----------||---|||||||||||--  6 [C] COG2010 Cytochrome c, mono- and diheme variants
---|------|--||-|--|------|||-------||----|||||--|||||||--||||||--  6 [Q] COG2132 Putative multicopper oxidases
----------------|-||-------------------------|--||--||||---||-||--  6 [Q] COG2931 RTX toxins and related Ca2+-binding proteins
||||----|||--||-||||||----||||||||||||----|||||-||||||||||||||||||  5 [EH] COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase
|||||||||||||||---||-|----||||----||||----|||||-||-|-|||--||||||--  5 [Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
-------------||||||||||||||||||||||||||||||||||-||||||||||||||||||  5 [I] COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase
||-||||||||||---|-||-|----|||-------||----|||||-||||---|||||||||--  5 [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing
-------------||-||||||||--||||||||||||----||||||||||||||||||||||||  5 [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase
|||||||||||||||-||||||--||||||||||---|-|--||||||||||||||||||||||||  5 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs
--|-|------|-||-|-||-------|||------|-----|||||--|-----|---||-||--  5 [Q] COG0412 Dienelactone hydrolase and related enzymes
|||||||||||||||-||||||||-|||||||||||||----|||||-||||||||||||||||||  5 [R] COG0517 FOG: CBS domain
|-||--|||----|--|-||-|--|||||-|||||||||---|||||-||||||||||||||||--  5 [R] COG0546 Predicted phosphatases
-------------||||||||||||-|||||||-||||----|||||-||||||||--||||||--  5 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
----||----|--|||--||||--|||---|-----------||||--||-|||||--|||-||||  5 [R] COG0666 FOG: Ankyrin repeat
|||-----||---|-------|----||||-------|----|||||-||||---|---||-|---  5 [H] COG0684 Demethylmenaquinone methyltransferase
--|--|-|-|---|||-|||||||---|||||||||||----|||||-||--|--|||-|||||--  5 [G] COG0726 Predicted xylanase/chitin deacetylase
--|||||||-|||---||||||||--|||||||-||||----|||||-||||---||||||||---  5 [E] COG0747 ABC-type dipeptide transport system, periplasmic component
-------------|||||||||--||----||||||||----||||||||||||||||||||||||  5 [O] COG0760 Parvulin-like peptidyl-prolyl isomerase
----||----------||||||||||-|||||||||||||||||||||||||||||||||||||||  5 [L] COG0776 Bacterial nucleoid DNA-binding protein
|-||||----|||---|-||||--|-|||-|---||||----|||||-||||||||||||||||--  5 [R] COG0824 Predicted thioesterase
-|-||||----------|-|||----------|--|-|----|||||-|-|-||-|||-|||||--  5 [L] COG0863 DNA modification methylase
---|---------||-----||----|||-----|-||----||||||||--||||---|||||--  5 [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1
--|||||||--||||--|-|-|-----||-||||||||--|-|||||-|||-||||---||-||--  5 [ER] COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
-||-||--||||-----|||||||--|---|--||-||----||||---||||--|---|||||--  5 [P] COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component
--||--||----|---|--||||||||||-|---|-||----|||||-||--|--|--|||-||||  5 [C] COG1301 Na+/H+-dicarboxylate symporters
--|||||||||||||-||-|-|--|||||-||||||||----|||||-||--||||--||||||--  5 [Q] COG1335 Amidases related to nicotinamidase
--||----|-|-|||||-||||----|||||-||--||||------|-||--||||--|||-|---  5 [O] COG1404 Subtilisin-like serine proteases
----------------||||||||------||||||||----|||||-||||||||------||--  5 [NU] COG1459 Type II secretory pathway, component PulF
---|----|-||||--|-||-|----||||----||||----||||||-|--|--|---|||||||  5 [C] COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2
-------------||||||-|---|--|||-|----||----|||-|-||--||||---|||||||  5 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily
-----|--|-||---------|-----||-------------|||-|--|-----|---|||||--  5 [C] COG1804 Predicted acyl-CoA transferases/carnitine dehydratase
---|------||||--|-||-|----||||----||||----||||||-|--|--|---|||||||  5 [C] COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3
---|------|-|||-|----|--------------||----------||--||||--||||||||  5 [R] COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems
||||----||-|-------|-|----||||--||||||-|--|||||--|--|--|---|||||--  5 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
-------------------|-|----|||-||||||||||--|||||-||-----|---|||||--  5 [K] COG2188 Transcriptional regulators
||-|-----|---------|-|-----|||----|-------||||---|-----|--||||||--  5 [E] COG2303 Choline dehydrogenase and related flavoproteins
----------------||||||||------||||||||----|||||-||||||||--|---||--  5 [NU] COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB
---------------------|-----------------------|--||-|-||||||-|-----  5 [C] COG2863 Cytochrome c553
------------------------------------------|||||||-|||--|----------  5 [R] COG2916 DNA-binding protein H-NS
--|--------------|--------|||-|---||||-----------|-----|---||-||--  5 [S] COG3832 Uncharacterized conserved protein
-------------------------------------------------|-|---|---||-||--  5 [U] COG3847 Flp pilus assembly protein, pilin Flp
--|----------------|-------------------------|--||-----|---|--|---  5 [S] COG4104 Uncharacterized conserved protein
-------------------------------------------||----|-----|---|||||--  5 [K] COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain
---------------------------------------------|---|-----|---|--|--|  5 [S] COG5430 Uncharacterized secreted protein
|||--|||||||-||-||||-|----|||||--|||||----||||||||||||||--||||||--  4 [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases
|-||||-------||-||||||||||||||||||||||||||||||||||||||||||||||||||  4 [L] COG0210 Superfamily I DNA and RNA helicases
||||||--|||||---|-||||----||||-|----||----|||||-||||-||||||||||---  4 [C] COG0247 Fe-S oxidoreductase
|-||------||-||-||||||||||||||||||||||----||||||||||||||||||||||||  4 [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
|||||||||||||---|||||-||--||||||||||||----||||||||||||||||||||||||  4 [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase
||||||||||||||--||-||-|||-||||||-|||||-|--|||||-||||||||||||||||-|  4 [L] COG0350 Methylated DNA-protein cysteine methyltransferase
|-|||||||-|||||-||||-|--|-|||||--|||||----|||||-||--||||||||||||--  4 [R] COG0388 Predicted amidohydrolase
|||||||||||||||-||||-|----|---|--|---|----|||||--||||--|||||||||--  4 [FR] COG0402 Cytosine deaminase and related metal-dependent hydrolases
||||||||||||||||||||||---|||||||||||||----|||||-||||||||||||||||||  4 [M] COG0438 Glycosyltransferase
|-||||-------|||||||||||||||||||||||||||||||||||||||||||||||||||||  4 [O] COG0443 Molecular chaperone
|||---||||||-||-||||-|----||||||--||||----||||||||||||||--||||||||  4 [CE] COG0473 Isocitrate/isopropylmalate dehydrogenase
-------------|||--||||||||||||||||||||-|--||||||||||||||||||||||||  4 [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains
|||||||||||||||||-||||----|||||-||-|||----||||||||||||||||||||||--  4 [O] COG0501 Zn-dependent protease with chaperone function
|||-||--|--|-||||-||||--|-||||||||||||||||||||||||||||||||-|||||||  4 [LKJ] COG0513 Superfamily II DNA and RNA helicases
||||--|||---|||-|||-||--|||||-|||||||||||||||||-||||||||||||||||--  4 [V] COG0534 Na+-driven multidrug efflux pump
-||-----||-------|||||||--|---|--||-||----||||---|||---|---|||||--  4 [P] COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component
---|---------||-|-||-|----|----|--||||----|||||-|||-|--|---|||||--  4 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epimerases
|-||||||||||||||-|||-|----||||||||||||----|||||-||-||--|||-|||||--  4 [V] COG0842 ABC-type multidrug transport system, permease component
---|------||||--|-||-|----||||----||||----||||||-|--|--|---|||||||  4 [C] COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1
----||||--|||||-|-|||---|-----|-|-||||----|||||-||||-|||||||||||--  4 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases
|||---||||-|-----|||------|||||-|-||||----|||||--|-----|---|||||--  4 [G] COG1082 Sugar phosphate isomerases/epimerases
-----------------|--|---|||----|----||-|--|||||-||||---|---|||||--  4 [G] COG1129 ABC-type sugar transport system, ATPase component
|-||||||||||||||-|||-|---||||||||||||||||-|||||-||-|||||||-|||||--  4 [V] COG1131 ABC-type multidrug transport system, ATPase component
||-|-|||-|||----|-||-||||||||||----|||--|||||||-||--||||||||||||||  4 [D] COG1192 ATPases involved in chromosome partitioning
||||||--|||||||-||||||||--||||-|||||||-|||||||||||||||||---|||||||  4 [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
---|||--|-|||-------||-----||||---|-||----|||||-||-----|---|||||||  4 [I] COG1250 3-hydroxyacyl-CoA dehydrogenase
--|-------------|----------||-|||||||||---||||||-------|---||-|---  4 [L] COG1484 DNA replication protein
----------|||---|----|--|--||-------||----|||----|-----|---||-||--  4 [C] COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs
----------------|-----------------|-|-----|||||-|||--|||---|||||||  4 [V] COG1566 Multidrug resistance efflux pump
--|-||----|-------||------|||-|-----------|||||-||-|---|---|||||--  4 [R] COG1741 Pirin-related protein
--------------------||----||||||||||||----|||||-||||-|||||||||||--  4 [E] COG1760 L-serine deaminase
------|||-------|-|||---------|-----|-----|||||--|--||||---|||||--  4 [M] COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
--|--------------|--|---|-|--|||----||----|||||-||||---|---|||||--  4 [G] COG1879 ABC-type sugar transport system, periplasmic component
|-------|----------|------|----|||||||----||||------|||||||||-||--  4 [R] COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog
---|----|--|-||-----||----||||----|-|-----|--||-||-----|---|||||--  4 [I] COG2030 Acyl dehydratase
--|||||||-||--|-|----|----|||--|||||||----|||||-||||---|||||||||--  4 [Q] COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism
--------|----|--||-|||----|||-||||||||-----------|--||||||||||-|--  4 [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase
----------|||--------|--||-||-------||----|||----|-----|---||-||--  4 [C] COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs
----||---------------|----|||-----||------|||||-||--|||||||||-||--  4 [S] COG2353 Uncharacterized conserved protein
----------------|--||-||||-||-------------||||||||||||||||||||||||  4 [M] COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins
------------------||------|---------------------||-----|---||-||--  4 [ER] COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins
------------------||-------|-|------------|||||-||||-|||---|||||||  4 [C] COG3288 NAD/NADP transhydrogenase alpha subunit
-------------------|------||||------|-----|||||--|-----|-----||---  4 [Q] COG3319 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases
-------------------------------------------------|--|-||----------  4 [NU] COG3419 Tfp pilus assembly protein, tip-associated adhesin PilY1
----------------|-||----------------------|||-|--|-----|||--|--|--  4 [P] COG3696 Putative silver efflux pump
|||||||||||||---||||||--|-||||||||||||-||||||||-||-||--|--|||||---  4 [G] COG3839 ABC-type sugar transport systems, ATPase components
--|------------------------||-----||-|-----|||---------|---||-|---  4 [L] COG4584 Transposase and inactivated derivatives
------------------||-|----|||-||||||||-----------|-----|---||-||--  4 [T] COG4585 Signal transduction histidine kinase
-----------------|||------|||-------------||||---|-----|---|||||--  4 [PR] COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit
----------------||||----------------------|||||-||||||||----------  4 [U] COG4796 Type II secretory pathway, component HofQ
-------------------------------------------------|--||||----------  4 [NU] COG4966 Tfp pilus assembly protein PilW
------------------------------------------------||--||||----------  4 [NU] COG4968 Tfp pilus assembly protein PilE
------------------------------------------------||--||||------|---  4 [NU] COG4970 Tfp pilus assembly protein FimT
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  3 [J] COG0008 Glutamyl- and glutaminyl-tRNA synthetases
|||||||||||||||---||||--------|-|-|-||----|||-|-||-|||||||-||||---  3 [E] COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family
|||-||--||---||-||||-|----||||||-|||||----||||||||||||||||||||||--  3 [E] COG0019 Diaminopimelate decarboxylase
--||||-|--|||||-||||||----||||||||||||----||||||||||||||||||||||--  3 [E] COG0031 Cysteine synthase
-|||||||||-||||-|-||||----|||-||||---|----|||||-|-||-|||---|-|||--  3 [P] COG0038 Chloride channel protein EriC
||||----||---|||||||||||||||||||||||||----|||||-||||||||||||||||||  3 [J] COG0042 tRNA-dihydrouridine synthase
|||||||||||||||-||||||----||||||--||||----||||||||||||||--||||||--  3 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase
|-||--|||---||||--|--|-----||-|-----||-|--|||||-||--|--|---|||||--  3 [L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  3 [J] COG0143 Methionyl-tRNA synthetase
-|-----------||-|---||-|--|||||---|-||----||||||||||||||||||||||--  3 [H] COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
||||-||||||-|||-||-||------||||-||-|||-||-|||||-|||||--|||--||||||  3 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
----------------||||||---||||||||||||||-|||||||-||||||||||||||||-|  3 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases
----------------|-||||||---||-||||||||----|||||-||||||||||||||||||  3 [I] COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III
|||-----||------||||-|----|||-||---||-----|||||-||||||||---|||||--  3 [E] COG0347 Nitrogen regulatory protein PII
|||||||||||||---||||||||||||||||||||||||||||||||||||||||||||||||||  3 [L] COG0358 DNA primase (bacterial type)
---|||||--|||----|||-|--|-||||||||-|||-||||||||-||-||--|---||||---  3 [G] COG0395 ABC-type sugar transport system, permease component
---|||||---||||-||||-|-----|||----||||----|||||--|--||||---|||||--  3 [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase)
----||----||||||--||||----|||-----|-||----|||-|-||--||||||-||-||--  3 [E] COG0405 Gamma-glutamyltransferase
--|-||-----|-||-||||||----||||||||||||----|||||-||-||--|---|||||--  3 [G] COG0406 Fructose-2,6-bisphosphatase
|||-----|--|-||-|-||-||||--||-||||||||----|||||-||||||||||||||||--  3 [I] COG0439 Biotin carboxylase
|||-|||||-|||||||||||||||--|||-||-||||----||||||||-||--|||||||||||  3 [O] COG0450 Peroxiredoxin
---|||----|||||---||-|||--||||-|||||||-|||||||||||||||||---|||||||  3 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes
|||||||||||||||-||||||-|-|||||||||||||----|||||-||||||||||||||||--  3 [F] COG0518 GMP synthase - Glutamine amidotransferase domain
--|----------||-|-||||----|||-----|-||----|||||-||--||||||-|||||--  3 [R] COG0523 Putative GTPases (G3E family)
||||||--||||||||--|||-||--|||||||||||||||||||||-|||||--|---|||||||  3 [E] COG0531 Amino acid transporters
|||||||||||||---||||-|-----||-||--|-||-----------|-----|----|-|---  3 [R] COG0535 Predicted Fe-S oxidoreductases
|------------||||||||||||||||||||||||||-|||||||-||||||||||||||||||  3 [O] COG0542 ATPases with chaperone activity, ATP-binding subunit
||||||-||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  3 [E] COG0547 Anthranilate phosphoribosyltransferase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  3 [K] COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)
|||-||--||-|-||--||--|----|||--|---|||-------|---||-||||---|||||--  3 [S] COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit
--|||||||-|||---||||||||-||||||||||||||||||||||-||||---||||||||---  3 [EP] COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components
|||||||||||||||-|||||-----|||||-----------|||-|--|--||||---|||||--  3 [C] COG0644 Dehydrogenases (flavoproteins)
|||-----||-|-||-|---||-----||||--|||||----||-||-||--|--|---|||-|-|  3 [R] COG0655 Multimeric flavodoxin WrbA
|||||||||||||-||||||||--|||||-||||||||----||||||||--||||||||||||||  3 [M] COG0668 Small-conductance mechanosensitive channel
||||--||-|-|-||||-||||--|-||||||||||||----|||||-|||||--|||-|||||||  3 [I] COG0671 Membrane-associated phospholipid phosphatase
-||||-|||||||||-||||-|--|-||||||||||||----|||||-|||||--|--||||||--  3 [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid)
|||||||||||||---||||-|---||||||---||||----|||||-||--|--|---|||||--  3 [R] COG0714 MoxR-like ATPases
|||-----||---||---|||---|-----||||-||-----|||||||||||--||||-------  3 [C] COG0716 Flavodoxins
--|-||--|-|||---||||||---||||||||-||||--|||||||-||||||||||||||||--  3 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins
----------------||||||||------||||||||----||||||||||||||||||||||||  3 [I] COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases
-----------------|---|||||||||||||||||||||||||||||||||||||||||||||  3 [K] COG0782 Transcription elongation factor
---|------------|-||-|----|||-------||----|||-|-|||||--|||||||-|--  3 [F] COG0788 Formyltetrahydrofolate hydrolase
-------------|||-----|--------------------|||||-||||-|||||||||||--  3 [R] COG0790 FOG: TPR repeat, SEL1 subfamily
------------------||-|||--||||||---|||----|||||-||||||||||||||||--  3 [M] COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
|-|------|------|-||||||------------------|||||-||||||||||||||||||  3 [U] COG0811 Biopolymer transport proteins
--||--|||--------|||----||----|----|||----|||||-||--|--||||||-||--  3 [NT] COG0835 Chemotaxis signal transduction protein
----------------|-||||||------------------|||||-||||||||||||||||||  3 [U] COG0848 Biopolymer transport protein
----------------|-|||---------------------|||||-|||||||||||---||--  3 [M] COG0859 ADP-heptose:LPS heptosyltransferase
------------------||-|----|||-|---||||----||||||||||||||||||||||||  3 [P] COG0861 Membrane protein TerC, possibly involved in tellurium resistance
--||||----|||||-|----|----||||||--|||-----|||||-||--||||---|||||||  3 [C] COG1048 Aconitase A
|||---|||||||---|-||-|----||||||-|-|||-------|--||-----|---|||||-|  3 [F] COG1051 ADP-ribose pyrophosphatase
--------------------||||-||---||||||||-|||||||||||||||||------||--  3 [G] COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)
--||--||--||-|||||||||||--||||||||||||||||||||||||||||||||||||||||  3 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components
|||-|||||||||----|||||--------|-----|-----|||||-|||||||||||||-|---  3 [C] COG1145 Ferredoxin
---|||----|||||--|||||----||||-|-|||||----|||||-||||||||--||||||||  3 [E] COG1171 Threonine dehydratase
-----------------|--|-----|--|-|----||----|||||-||||---|---|||||--  3 [G] COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components
--|||||||-|||---||||||||-||||||||||||||||||||||-||||---||-|||||---  3 [EP] COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components
---|||||--|||----|||-|--|-||||||||||||-||||||||-||-||--|---||||---  3 [G] COG1175 ABC-type sugar transport systems, permease components
----------------||||||||||||||||||||||-|--||||||||||||||||||||||||  3 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases
--|-----------|---||--||---||-------||----------||-|||||---|||||--  3 [S] COG1262 Uncharacterized conserved protein
------------------||-------|||------------|||||-||||-|||---|||||||  3 [C] COG1282 NAD/NADP transhydrogenase beta subunit
--|-----|-----------||----|----|-|||||----|||||-||||-|||||-||||---  3 [E] COG1296 Predicted branched-chain amino acid permease (azaleucine resistance)
|-|---||||||----||||-|-----||||----|||-----------||||--|---||-||--  3 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases
|-|---|||||-|||-|-||--||--||||||--|||-----|||||-||||---|---|||||--  3 [R] COG1409 Predicted phosphohydrolases
----------------||||-|----|---||--||------|||||-||||||||---|||||||  3 [S] COG1434 Uncharacterized conserved protein
-------------||---||||||--||||||||||||----|||||-||||||||||||||||--  3 [H] COG1539 Dihydroneopterin aldolase
---|||||--|||----|||-|--|-||||||||-|||----|||||-||-||--|---||||---  3 [G] COG1653 ABC-type sugar transport system, periplasmic component
--|---||--|-|-----||-|----||||||||||||----|||||--|--|--|---|||||||  3 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins
----------------|-----||||----|-----||----||||||||||||||--||||||||  3 [T] COG1734 DnaK suppressor protein
--||------|-|-----|||-----|-----|||--|-----||||-||||||||--|||||---  3 [P] COG1840 ABC-type Fe3+ transport system, periplasmic component
|-|-|-|||-|||-|-||||||----||||||-|||||----|||||--|-|-|||---|||||||  3 [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family
--|-------------|----|--------------------|||||-||-|---|||||--|---  3 [P] COG1858 Cytochrome c peroxidase
---|--|||-|-|||-|--|------|||-|||-||||----|||||-||-----|------||--  3 [H] COG1893 Ketopantoate reductase
--------------------|||||||---||||||||||||||||||||||||||---|||||--  3 [G] COG1925 Phosphotransferase system, HPr-related proteins
----------------||||||-----||-||-|||||----|||||-||||||||--||||||||  3 [K] COG1959 Predicted transcriptional regulator
-----||---|-------||-|----|||-|-||||||----|||||-||--|--|---|||||--  3 [L] COG1961 Site-specific recombinases, DNA invertase Pin homologs
----------|||--------|-----||-------||----|||----|-----|---|||||--  3 [O] COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family
----||-----|-||--|||||--------||-|||||----|||-|-|-||-|||---|||||--  3 [G] COG2017 Galactose mutarotase and related enzymes
--||||--|-|||---|--|-|----|||-------|-----|||||--|-|---|--||||||--  3 [R] COG2041 Sulfite oxidase and related enzymes
-|---------------|||||---||---------||-|--------||-----|---||-||--  3 [P] COG2059 Chromate transport protein ChrA
|-|-||----|||---|-||-|-----||-||---|||----|||||-||||-|||-|-|||||--  3 [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
--|-----|----------|-|----|||||--||-||----|||||--|---|||---|||||--  3 [S] COG2128 Uncharacterized conserved protein
--||||----||--|---||-|----||------|-||----|||||--|--|--|---||-||--  3 [PR] COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases
-|----||-|--------|--|---------------------------|-----|----|-|---  3 [O] COG2192 Predicted carbamoyl transferase, NodU family
|-||||-||-|||||-|||||||||-|||||||||||||---|||||-||||-|||||||||||--  3 [P] COG2217 Cation transport ATPase
||||||||||||||---|||||----|||-|-||||||----|||||-||-||--|--|||||--|  3 [R] COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold
----------------|---------||||----|-||----|||-|--|-----|----||-|--  3 [P] COG2223 Nitrate/nitrite transporter
--|-------------|----|----|||||-----------|||||-||-----|||||||||--  3 [M] COG2230 Cyclopropane fatty acid synthase and related methyltransferases
---|-------|-||----|-|----||||----|-||----|||||-||||-|||---|||||--  3 [S] COG2259 Predicted membrane protein
---|||---|||-----|---|------------|-------|||||-||--|--|--|||||---  3 [R] COG2391 Predicted transporter component
|-||||--|||||||-----------|-------|----------|---|-----|---||||---  3 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog
----||----|||------|------|||------|||----|||-|-||--||||----|-||--  3 [G] COG2513 PEP phosphonomutase and related enzymes
----------|-|------||-----||-|-||||||-----|||||-||||-|||---|||||--  3 [S] COG2606 Uncharacterized conserved protein
-------------------|------|||-||--||-|----|||-|--|-----|----|-||--  3 [S] COG2764 Uncharacterized protein conserved in bacteria
--|-----|-------|-||-|--------------|-----------||-----|---||-|---  3 [T] COG2770 FOG: HAMP domain
--------------------------|||--|--||||----|||||--||||--||||||-|---  3 [G] COG2814 Arabinose efflux permease
---------------------|--------|-----------|||||-||||-|||----|---||  3 [R] COG2823 Predicted periplasmic or secreted lipoprotein
--||---------||--|---|----|||-||---|-|-----------|-|---|--|||||---  3 [E] COG2873 O-acetylhomoserine sulfhydrylase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  3 [J] COG2890 Methylase of polypeptide chain release factors
-------------||---||-------||-------------------||-----|---||-||--  3 [I] COG3000 Sterol desaturase
------------------------------------------|||-|-||--|--|----------  3 [P] COG3131 Periplasmic glucans biosynthesis protein
------------------||-------||-------|------------|-----|----|-||--  3 [I] COG3239 Fatty acid desaturase
-------------------|------|||||-----|--------|---------|---||-|---  3 [Q] COG3321 Polyketide synthase modules and related proteins
----||-----|-|-------|------------|-|---------|--|-||--|---|||||--  3 [G] COG3386 Gluconolactonase
--|-|------|-------|-|--||-||-|-----||----|||-|--|-----|----|-|---  3 [S] COG3391 Uncharacterized conserved protein
--------------------|---------------------|||||-|--|---|---||-||--  3 [M] COG3713 Outer membrane protein V
---------------------|------------|-------|||||--|-|---|---||||---  3 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase
--||----|-|-|----|||||--|||---||||||-||||||||||-||||-|||--||||||--  3 [E] COG3842 ABC-type spermidine/putrescine transport systems, ATPase components
---------------------|-----||-------------|||||--|-|---|---|-|-|--  3 [Q] COG3971 2-keto-4-pentenoate hydratase
------------------------------------------------||-----|---||-|---  3 [T] COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system
---|---------------|--------------|--|-------|---------|----|-----  3 [Q] COG4264 Siderophore synthetase component
-------------------------------------------------|-----|----|-|---  3 [C] COG4313 Protein involved in meta-pathway of phenol degradation
-------------------|-----------------------------------|------|---  3 [S] COG4675 Microcystin-dependent protein
-------------------------------------------------|--||||----------  3 [NU] COG4726 Tfp pilus assembly protein PilX
---|||--||-||----|||||----||||||--||||----|||||--|-----|---|||||--  3 [MR] COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily
||----||-|----------------|||-|--------------|---|-||--|---||-||--  3 [U] COG4962 Flp pilus assembly protein, ATPase CpaF
------------------------------------------|||||-||--||||----------  3 [NU] COG4967 Tfp pilus assembly protein PilV
|||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||--  3 [E] COG4992 Ornithine/acetylornithine aminotransferase
-------------|---|------------|------------------------|---|---|--  3 [M] COG5434 Endopolygalacturonase
||||||--|||||-|-|-||||||--|||||---||||----|||||-||-|||||||||||||--  2 [H] COG0001 Glutamate-1-semialdehyde aminotransferase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||---|||||||  2 [J] COG0009 Putative translation factor (SUA5)
||||||||||||-||-||||||----||||||||||||----||||||||||||||||||||||--  2 [F] COG0015 Adenylosuccinate lyase
|||-||-||||||||-||||-|----||||||-|||||----||||||||||||||--||||||--  2 [EH] COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]
---|--||---|----|-|||------||||----|||----|||||-||--||||---||-||--  2 [H] COG0029 Aspartate oxidase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [D] COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control
---------|---||-||||||||||||||||||||||||||||||||||||||||||||||||||  2 [J] COG0050 GTPases - translation elongation factors
|||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||--  2 [E] COG0069 Glutamate synthase domain 2
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [R] COG0073 EMAP domain
|||---||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0084 Mg-dependent DNase
||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||--  2 [H] COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase
||||---|-||--||--|||-|||--||||||||||||----|||-|-||-|-|||--||||||-|  2 [R] COG0110 Acetyltransferase (isoleucine patch superfamily)
|||||||||||||||-||||-|----||||||--||||----|||||-|||||--|||||||||--  2 [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases
||||||||||||||||||||-|||||||||||||||||-|||||||||||||||||||||||||||  2 [E] COG0112 Glycine/serine hydroxymethyltransferase
||||--|||||||||||-||-|------------|-||----------||---|||---|||||--  2 [BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein
|||----||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  2 [EG] COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase
||||||-||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  2 [E] COG0134 Indole-3-glycerol phosphate synthase
||||||||||||||||||||||||||||||||||||||----||||||||||||||||||||||||  2 [H] COG0142 Geranylgeranyl pyrophosphate synthase
-|-|--||||||||||-|||||||--|||-||||||||----|||||-||||||||--||||||--  2 [J] COG0144 tRNA and rRNA cytosine-C5-methylases
||||||-||||||||-||||||----||||||||||||----||||||||||||||||||||||--  2 [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I
||||----|||||||-||||||||||||||||||||||||||---|---|---|||||||||||||  2 [J] COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases
--------|-||-||-|-||-|----|||-|-----||----||||||||--||||---|||||--  2 [P] COG0155 Sulfite reductase, beta subunit (hemoprotein)
-|--||||-----||||-||||||---|||----|-||----|||||-||||||||||||||||||  2 [H] COG0156 7-keto-8-aminopelargonate synthetase and related enzymes
--||||||--|||||----|-|----|||||---|-||----|||||-|||----|---||||---  2 [E] COG0160 4-aminobutyrate aminotransferase and related aminotransferases
-|-|||----||||||||||||||||||||||||||||-|||||||||||||||||||||||||--  2 [G] COG0166 Glucose-6-phosphate isomerase
||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||--  2 [E] COG0169 Shikimate 5-dehydrogenase
|||||||||||||||-||||-|----||||-|||||||----|||||-||||||||||||||||||  2 [E] COG0174 Glutamine synthetase
-||||-||-||||||---||||----|||-|-----||----||||||||--||||---|||||--  2 [EH] COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes
|-||------------|||||||||||||||||||||||||||||||-||||||||||||||||||  2 [L] COG0178 Excinuclease ATPase subunit
--||||--|----|||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
--||||--|----|||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
|-|||||||-|||||||||-|||||-||||||||||||-|||||||||||||||||||||||||||  2 [F] COG0209 Ribonucleotide reductase, alpha subunit
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  2 [J] COG0223 Methionyl-tRNA formyltransferase
||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||--  2 [P] COG0226 ABC-type phosphate transport system, periplasmic component
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  2 [J] COG0242 N-formylmethionyl-tRNA deformylase
-------------||---||-|-----|||------------|||||-|||-||||---|||||--  2 [H] COG0259 Pyridoxamine-phosphate oxidase
||----||-||||-|---||------|---|-||--||||--|||-|-|-|-||||||--|-||--  2 [L] COG0270 Site-specific DNA methylase
--||-------------||-||--|||||-||||||||||||||||||||||||||-|||||||||  2 [C] COG0280 Phosphotransacetylase
--|||||||-|||||--|||-|----|||-|||-||||----|||||-||||||||--||||||||  2 [C] COG0281 Malic enzyme
|--|------||-||---||-|----|||||-||--||----|||||-||||||||||||||||--  2 [P] COG0288 Carbonic anhydrase
--|--------|-|--|-||||||--|||----|--|-----|||||-||||---|---||-|---  2 [G] COG0296 1,4-alpha-glucan branching enzyme
|||||||||||||---|-||-|----|||||---||||----|||||-||||---|||||||||--  2 [H] COG0303 Molybdopterin biosynthesis enzyme
--|-||----||-|||--||-|----||||-|||--------|||||-||||||||---|||||--  2 [E] COG0308 Aminopeptidase N
|||-|||||||||---||||-|-----||-|------|----||||||||||||||---|||||--  2 [R] COG0312 Predicted Zn-dependent proteases and their inactivated homologs
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  2 [R] COG0313 Predicted methyltransferases
--|----------||-|-||-|----||||----|-||----||||||||||||||---|||||||  2 [S] COG0316 Uncharacterized conserved protein
-------------||-||||||||||||||||||||||----||||||||||||||||||||||||  2 [J] COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase
--|----------||-||||||----||||||||||||----||||||||||||||||||||||--  2 [R] COG0325 Predicted enzyme with a TIM-barrel fold
-||-||--||-|------||----------|-----------|||-|-||||-|||||||||||--  2 [C] COG0348 Polyferredoxin
--|-|||||----||-|-||||----||||||-|||||----|||||-||||||||||||||||--  2 [H] COG0352 Thiamine monophosphate synthase
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  2 [C] COG0355 F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [J] COG0361 Translation initiation factor 1 (IF-1)
--|-||----|--||--|||-|----|||-||||||||-|--|||||-||-----|---||-||--  2 [G] COG0366 Glycosidases
|-||||--|-|||||-||||-|----||||-|--||||----|||||-||-|||||||||||||||  2 [C] COG0372 Citrate synthase
--||----|----|----|--------||--------|----|||||-|---|--|---||-||--  2 [P] COG0376 Catalase (peroxidase I)
|---||----|--|||--|-------||||------------|||-|--------|----|-|---  2 [G] COG0380 Trehalose-6-phosphate synthase
||-|--||---------|||-|--------||-||||-----|||||-||-|-|||--|-----||  2 [M] COG0381 UDP-N-acetylglucosamine 2-epimerase
|||||||||||||||-|-||-|||--|||||------|----|||||-||-|||||||||||||||  2 [H] COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases
-------------|||--|-|-----|---|||||||||---|||||--|--||||-------|--  2 [O] COG0386 Glutathione peroxidase
--||-------|-||---|||-----|||-|||||||||||||||||-||-|-|||---|||||--  2 [L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair
|-||----|----||-|-||-|----|||-||||||||----|||-|-||-|||||--||||||--  2 [T] COG0394 Protein-tyrosine-phosphatase
||-----|-||-----||||----|-|||-|--|--|-----|||||-||-|-||||||-||||--  2 [M] COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis
-|--|||||||||||-||---|----|---|--|--||----||||||-|--||||||----|---  2 [E] COG0421 Spermidine synthase
--|---||-----||-||||||||--|||||-----||----|||||-||-|||||||||||||||  2 [D] COG0424 Nucleotide-binding protein implicated in inhibition of septum formation
---|---------||---||-|----|||--|||||||--|||||||-||-|-|||---||-||--  2 [R] COG0431 Predicted flavoprotein
--|||||||-|||---||--||||-||---|||||||||||||||||-||||---||||||||---  2 [EP] COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
||||||||||||||||||||||----|||||||||||||---|||||-||||||||--||||||--  2 [R] COG0456 Acetyltransferases
|||||||||||||||-||||||--||||||||||||||||||||||||||||||||||||||||-|  2 [FE] COG0462 Phosphoribosylpyrophosphate synthetase
-|||||||--||||||-|||||||-|||||||||||||||||||||||||||||||--||||||--  2 [G] COG0469 Pyruvate kinase
||----||-|||-||-||||||||||||||||||||||----|||||||||||||||||||||-||  2 [M] COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase
|||-|||||-|||||-|-||-|---|-|||||--||||----|||||-|||-||||||||||||||  2 [P] COG0475 Kef-type K+ transport systems, membrane components
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [J] COG0480 Translation elongation factors (GTPases)
||||||||||||||||||||||----|||||--|||||----|||||-||||||||||||||||||  2 [D] COG0489 ATPases involved in chromosome partitioning
||||||||||||||-|||||||||||||||||||||||||||||||||||||||||||||||||||  2 [O] COG0492 Thioredoxin reductase
|||---|||--|-||-|||||||||-||||||||||||----|||||-||||||||||||||||--  2 [I] COG0511 Biotin carboxyl carrier protein
---|||----||-||||-||-|||--||||||||||||||||-|-|--|||||--||--|--|---  2 [RTKL] COG0515 Serine/threonine protein kinase
||-|||||-|--|||-||||||-|-|||||||||||||----||||||||||||||||||||||--  2 [F] COG0516 IMP dehydrogenase/GMP reductase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [J] COG0525 Valyl-tRNA synthetase
-------||---|||-|-|--|-----||-|-----||----||||||||--|--|--|-||||--  2 [P] COG0529 Adenylylsulfate kinase and related kinases
|||||||||-|||||||-||||||-|||||||||||||||||||||||||||||||||||||||||  2 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
|||-||||||-|-||-||--|---|-|||-||-|-|||----|||||-||---|||---|----||  2 [HC] COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases
-------------||---||-||||-|---------------||||||||||||||-------|--  2 [O] COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1
|||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||-|  2 [E] COG0548 Acetylglutamate kinase
||||||||||||------||-|-----||-|------|----|||||-||||||||---|||||--  2 [O] COG0555 ABC-type sulfate transport system, permease component
---|---------||||||||||||-|---||||||||||||||||||||||||||||||||||--  2 [K] COG0557 Exoribonuclease R
|||||||||||-|||-----|--|--||||||----------|||||-||||||||||||||||--  2 [E] COG0560 Phosphoserine phosphatase
-------------|||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [J] COG0564 Pseudouridylate synthases, 23S RNA-specific
--------|----||-|||||||||||||||||||||||||||||||-||||||||||||||||||  2 [J] COG0566 rRNA methylases
-------------||------|||--||||----|-||----||||||||||||||---|||||||  2 [C] COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes
---|||-|--|-||||-|-|||--|-||||||||||||-||||||||-||||---|---|||||--  2 [C] COG0584 Glycerophosphoryl diester phosphodiesterase
----||-----|------||-|--||||||||--||||----|||||||||||||||||--|||--  2 [S] COG0586 Uncharacterized membrane-associated protein
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0587 DNA polymerase III, alpha subunit
----------------||||-|||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0593 ATPase involved in DNA replication initiation
-||---|-|-||-||-||||||----|||||||||||-----|||||-|||||--|||||||||-|  2 [P] COG0598 Mg2+ and Co2+ transporters
----------|-|||-||||||---|-|||||||||||----|||||-|||||--|||||||||||  2 [R] COG0612 Predicted Zn-dependent peptidases
-||||||||-|||----|||||----||||||||||||----|||||-||||---|||||||||--  2 [P] COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component
|||||||||-|-|---|||||||||-||||-----|||----||||||||||||||||||||||||  2 [OU] COG0616 Periplasmic serine proteases (ClpP class)
-------------|||||||||||||||||||||||||----||||||||||||||||||||||||  2 [J] COG0617 tRNA nucleotidyltransferase/poly(A) polymerase
|||||||||||||---||||||-||-|||||---|-||----||||||||||||||||||||||||  2 [J] COG0621 2-methylthioadenine synthetase
--||||||--|||||--|--||----||||||||||||----|||||-||||||||||||||||--  2 [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases
||||--|||-------||||||--|||||-||||||||----||||||||||||||||||||||||  2 [R] COG0628 Predicted permease
----------------|||||||||||||-|||||||||---||||||||||||||||||||||||  2 [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases
--|-|||---||-||--|||-|||--|||||||-||||-|--|||||-||||||||---|||||--  2 [R] COG0637 Predicted phosphatase/phosphohexomutase
--||--|||--------|||-|--||----|----|||----|||||-||--|--||||||-||--  2 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases
|-||---------|||--||||--|-||||||||||||----|||||-||||||||||||||||--  2 [O] COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  2 [U] COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase)
---|||||--||||||-||-------||||||||||||----|||||--|-----|---|||||--  2 [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase
--|----------||||-||--||--||||-|---|||----|||-|-||-|---|||-||-|---  2 [P] COG0659 Sulfate permease and related transporters (MFS superfamily)
---|||----|||||-||||||---|||||-|--||||----|||||-||--|--||--||-||--  2 [C] COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)
||||||||||||||||||||||||||||||||||||||-|--||||||||||||||||||||||||  2 [U] COG0681 Signal peptidase I
-||||||||||||||-|-||||--||-||-|--|||||-||||||||-||-||--|--||||||--  2 [R] COG0693 Putative intracellular protease/amidase
|-|-||--|--|-|||--||||--|||||-||||-||-----|||||-||||||||||||||||||  2 [L] COG0708 Exonuclease III
-------------||----|-|----|----|-|--------||||||||||||||------||--  2 [E] COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase
|--|----|----||-|||--|--|-|---|||-||||-|--|||||-|-||---|||-||-|---  2 [F] COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases
----------------||||||--||||||||--||||----||||||||||||||||||||||||  2 [M] COG0739 Membrane proteins related to metalloendopeptidases
-----------------|||||----||||||||||||----||||||||||||||||||||||--  2 [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein)
-----------------|||||----|||||-----||-------|-||||||--|||||||||--  2 [E] COG0757 3-dehydroquinate dehydratase II
----------------|-||-------|||------------|||||-||||||||||||||||||  2 [Q] COG0767 ABC-type transport system involved in resistance to organic solvents, permease component
----------------||||||||||||||||||||||----||||||||||||||||||||||||  2 [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2
----------------||||||||||||||||||||||----||||||||||||||||||||||||  2 [D] COG0772 Bacterial cell division membrane protein
----------------||||||||||||||||||||||----||||||||||||||||||||||||  2 [M] COG0773 UDP-N-acetylmuramate-alanine ligase
--|--------------|--|||||||||-||||||||||--||||||||||-|||||||||||--  2 [F] COG0775 Nucleoside phosphorylase
-----------------|||||||||----------------|||||-||||||||||||||||||  2 [R] COG0795 Predicted permeases
-----------------|||----|-----||||--||----|||||-||||||||||-|||||--  2 [G] COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase
----------------|--||---------------------|||||-||||||||||||||||--  2 [M] COG0810 Periplasmic protein TonB, links inner and outer membranes
--|-----|---------||--||------------------|||||-|||||--|||||||||||  2 [U] COG0823 Periplasmic component of the Tol biopolymer transport system
|||------|-|----|--|||--------||||||||----|||||-||||-|||||||||----  2 [O] COG0826 Collagenase and related proteases
-------------||---------------||--|||-----|||||--|-----|||--------  2 [E] COG0833 Amino acid transporters
||||--||-|||-|||-|-|-|--|||||-||||||||----|||||-||-|-|||---|||||--  2 [R] COG1011 Predicted hydrolase (HAD superfamily)
|||||||||||||---|||||---|--||-||--||-|----|||||-|------||||---||--  2 [C] COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit
--||----------|--|||------||||||||||||----||||||||||-|||||||||||--  2 [E] COG1045 Serine acetyltransferase
|||||||||||||-------||--|-----------------|||||-|||||||||||-------  2 [O] COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2
-----------|-||---||------||||-------|----|||||--||--|||---|||||--  2 [C] COG1062 Zn-dependent alcohol dehydrogenases, class III
--||---||---||||-|-|||||--|||-|||--|||----|||||-||-||--|---|||||--  2 [R] COG1073 Hydrolases of the alpha/beta superfamily
|-||-||||--||---|-||||----|||||||---||----|---|--|--||||---||-||||  2 [M] COG1091 dTDP-4-dehydrorhamnose reductase
--|-----|----||||||||||||-||||||||||||----||||||||||-|||||||||||||  2 [E] COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes
|||||||||||||||||||||||||||||||||||||||-||||||||||||||||||||||||||  2 [G] COG1109 Phosphomannomutase
------------------||-------||--------|----|||||-||--||||||||||||--  2 [P] COG1118 ABC-type sulfate/molybdate transport systems, ATPase component
----------------|-||-------|||------------|||||-||||||||||||||||||  2 [Q] COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component
||||----|||||---|||||||||||||-||||||||||||||||||||||||||||||||||||  2 [V] COG1136 ABC-type antimicrobial peptide transport system, ATPase component
||||||-|||||-----|||-|----|||||-----------|||-|-||--|--|||||||||||  2 [C] COG1146 Ferredoxin
----------------||----||||----|----|||----||||||||-----|||||||||--  2 [NU] COG1157 Flagellar biosynthesis/type III secretory pathway ATPase
---|----|-|-|----|-|||--||----||||||--|||||||||-||||-|||--||||||--  2 [E] COG1177 ABC-type spermidine/putrescine transport system, permease component II
-------------||-|||||||||||||||||-||||----||||||||||||||||||||||||  2 [J] COG1186 Protein chain release factor B
|||----|---|----|--||----|||||||||||||--|||||||-||||||||||||||||--  2 [M] COG1210 UDP-glucose pyrophosphorylase
|-|--||||---|-----||-|----|||||-----------|---|--||-|--|---||-||--  2 [R] COG1216 Predicted glycosyltransferases
-----------------|||----------|----||-----|||||-||-----|----------  2 [KT] COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
||||||||||-|||--||||-|----|||-||---|||||--|||||-|||-||||||||||||||  2 [P] COG1226 Kef-type K+ transport systems, predicted NAD-binding component
--|---|---||-|||||-|-|----|--||||||||-----|||||--|-|||||--||||||--  2 [P] COG1230 Co/Zn/Cd efflux system component
||||||||||||||||-|||-|||||||||||||||||----|||-|----|---|------||--  2 [R] COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
--||------------|----|-----|||------||----||||||||-|-|||----------  2 [E] COG1246 N-acetylglutamate synthase and related acetyltransferases
--|-------|-|-----||-|----|---||-|||||----|||-|-||-----|---|||||--  2 [M] COG1247 Sortase and related acyltransferases
--|-------------|----------||-|---|-||----|||||--|-----|---||-||--  2 [C] COG1251 NAD(P)H-nitrite reductase
--||---------||-|||||||||||||-|||||||-||||||||||||||||||||||||||||  2 [R] COG1253 Hemolysins and related proteins containing CBS domains
-||-|||||-|||----|-|-|---|--|-||||||||----|||||-||-|---|----|-|---  2 [C] COG1254 Acylphosphatases
|||||||||||||-----||||-----||-|----|-|--------|-||-----|---||||---  2 [H] COG1270 Cobalamin biosynthesis protein CobD/CbiB
--||||--|-------|-||--||--|||--|--||||----|||||-||||---|--||||||||  2 [C] COG1271 Cytochrome bd-type quinol oxidase, subunit 1
--------------------|-----|||-|---|-||----|||||-||-|---|||-|-|---|  2 [R] COG1279 Lysine efflux permease
------------------|--|------------|||-----|||||-||||||||--|||||---  2 [S] COG1289 Predicted membrane protein
--||------------|-||--||--|||--|--||||----|||||-||||---|--||||||||  2 [C] COG1294 Cytochrome bd-type quinol oxidase, subunit 2
--|-------------|-||||||--||||||||||||-|--|||||-||||||||||||||||||  2 [S] COG1295 Predicted membrane protein
-----------------|----||||----|-----||----||||||||-----||||---|---  2 [NU] COG1317 Flagellar biosynthesis/type III secretory pathway protein
----------------||------||----|----|||----|||||-||-----|||||||||--  2 [N] COG1344 Flagellin and related hook-associated proteins
--||--|||--------|-|----||----|----|||----|||||-||-----|--|||-||--  2 [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins
----------------||------||----|----|||----|||||-||-----|||||||||--  2 [N] COG1360 Flagellar motor protein
----------------||----||||----|----|||----||||||||-----|||||||||--  2 [NU] COG1377 Flagellar biosynthesis pathway, component FlhB
-------------------|||----|--||||||||||-|||||||-||||||||--||||||--  2 [P] COG1393 Arsenate reductase and related proteins, glutaredoxin family
-------------||---||-----------------------------|-----|--------||  2 [I] COG1398 Fatty-acid desaturase
---|--------------||-|-----||||||-|||-----|||---|---|--|---|||||--  2 [V] COG1403 Restriction endonuclease
----------------|---|-||------------------|||||-||--|--|--|---||--  2 [NU] COG1450 Type II secretory pathway, component PulD
|-|||||||--||||-||--|-----|---||-|||||----|||||-||-|---|---||||---  2 [C] COG1454 Alcohol dehydrogenase, class IV
----------------|-||-------|||------------|||||-||||||||||||||||||  2 [Q] COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component
--------------------||-||-|---||||||||----|||||-||||||||||||||||--  2 [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen
-----------|--|--|||-|---|||||||---|||----|||||-||||||||---|||||||  2 [G] COG1472 Beta-glucosidase-related glycosidases
--||||||---|-----|||||----|||-||-|||||----|||----|||---|--||||||--  2 [R] COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase
--|-------------||--|||||-----||||-|------|||||-||||||||----||||--  2 [H] COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis
--|||||||||||||-||||||--|||||-||||||||||||||||||||-|||||--|||||---  2 [H] COG1488 Nicotinic acid phosphoribosyltransferase
---------------------|||------------||----|||||-||||||||||||||||||  2 [O] COG1495 Disulfide bond formation protein DsbB
----------------|-----||||----|----|||----|||||-||--||||||||||||--  2 [K] COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
|||-|||||||||---||-|-|----|---|---|-||----|||||--|-----|---|||||--  2 [J] COG1514 2'-5' RNA ligase
|||-||--|-||--------------|||-----||||----|||||-||||---|--||||||--  2 [C] COG1526 Uncharacterized protein required for formate dehydrogenase activity
---|--||-||||---|||||-||--|||||----|-|----||||||||||||||---|||||||  2 [J] COG1530 Ribonucleases G and E
------||------------||----|--|----|-||----|||||-|||--|||--||------  2 [R] COG1540 Uncharacterized proteins, homologs of lactam utilization protein B
--------------------|-||--||||------------|||||-||||||||||||||||||  2 [M] COG1560 Lauroyl/myristoyl acyltransferase
--|||||||-|||---||||||--|--|||||||--------------|-|--|||||||||||||  2 [L] COG1573 Uracil-DNA glycosylase
--||||||----|---||--||-----||------|||--------|--|-----|---|||||--  2 [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold
||||||--|||||||-||--||----||||||||||||----||||||||||||||||||||||--  2 [E] COG1605 Chorismate mutase
---|||----|||--------|||--|-------||||----||||||||||-|||||||||||--  2 [I] COG1607 Acyl-CoA hydrolase
--|-||||||||-|--||-|||||--||||-|--|-||----|||||-||-|||||--||||||--  2 [R] COG1611 Predicted Rossmann fold nucleotide-binding protein
-----------------||-|---|-|---------||----|--||-||||---|---||-||--  2 [G] COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
-------------------|-|--||---------||-----|||-|-||-|||||---|||||--  2 [S] COG1652 Uncharacterized protein containing LysM domain
-------------------|-||||||||||||||||||---|||||-||||||||||||||||||  2 [D] COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins
--------------------|-||||||||||||||||----|||||-||||||||---|||||||  2 [M] COG1686 D-alanyl-D-alanine carboxypeptidase
|||||||||||||--|||-|-|----|||-|------|----|||-|--|-----|----------  2 [S] COG1690 Uncharacterized conserved protein
|-|||||||-|||----|-|||----||||||||||||----|||||-|------|------||--  2 [K] COG1695 Predicted transcriptional regulators
|||||-|||||||---|-----------------||||----|||||-|-||---|--|||||---  2 [H] COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein
----||---------------|----|----|--|||---|||||-|-||--|--|---|||||--  2 [O] COG1764 Predicted redox protein, regulator of disulfide bond formation
-||-||||-|-||---||---|----|||-|----|-|--|||||||-||---|||---||-||--  2 [O] COG1765 Predicted redox protein, regulator of disulfide bond formation
--||---|-----||--|-|-|----|-------|-||----||||---|--|--|-----|----  2 [P] COG1785 Alkaline phosphatase
--------|--|--------||----|||-|-|---||----|------||----|||-|||||-|  2 [I] COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit
--||||--|||||---|-||-|----||||----||||----|||||-||||||||||||||||||  2 [U] COG1826 Sec-independent protein secretion pathway components
--|----------------|||----||||-||||||------||-|--||-||||---|||||-|  2 [I] COG1835 Predicted acyltransferases
||||||-||-||-----|||------|||-----|--|-----------|||---|---||-|---  2 [R] COG1878 Predicted metal-dependent hydrolase
----------------||----||||----|----|||----||||||||-----|||||||||--  2 [NU] COG1886 Flagellar motor switch/type III secretory pathway protein
----||-----|-||----|||----||||||-|||||----|||||--|||||||---||||---  2 [P] COG1914 Mn2+ and Fe2+ transporters of the NRAMP family
------||-----|------||----||||----|-||----|||||-|||--|||--||---|--  2 [E] COG1984 Allophanate hydrolase subunit 2
||||||-||||||---||||-|-----||-|----|||----------|----|||||--|-||--  2 [R] COG1994 Zn-dependent proteases
--|-------------|||||---------||||||||----|||||-||||||||---||||--|  2 [L] COG2003 DNA repair proteins
|-|-----||||------------------------------|||||--|||---|--|||-||--  2 [R] COG2005 N-terminal domain of molybdenum-binding protein
---|---------||--|-|||--------|---||-|----|||||-||-----|---|||||--  2 [E] COG2008 Threonine aldolase
---|||--|-|||||--|--||----|||||-----||----|||-|--|--||||---|||||--  2 [C] COG2025 Electron transfer flavoprotein, alpha subunit
------||---|--------||-----||---|||-||-------|---------|----------  2 [O] COG2039 Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)
------||-----|------||----||||----|-||----|||-|-|||--|||--||---|--  2 [E] COG2049 Allophanate hydrolase subunit 1
-----------|--------||----|||-|-|---||----|------||----|||-|||||-|  2 [I] COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit
|||||||||||||-------------||--|--------------|---|-|---|---||-||--  2 [NU] COG2064 Flp pilus assembly protein TadC
------------------||----------||||||||----|||||-||||---|---|||-|--  2 [R] COG2081 Predicted flavoproteins
---|||--|-|||||--|--||----|||||-----||----|||-|--|--||||---|||||--  2 [C] COG2086 Electron transfer flavoprotein, beta subunit
-------------||---||----------|---|-||----|||-|---|||--|----------  2 [H] COG2091 Phosphopantetheinyl transferase
-||-|||||||||---|--|-||||-----------|-----||||||||-|||||--||||||--  2 [U] COG2095 Multiple antibiotic transporter
||||----||||------||-|----|||-----|-||-----------------|----------  2 [S] COG2138 Uncharacterized conserved protein
---------------------------||--|---|||----|||||-||-----|---|||||-|  2 [F] COG2169 Adenosine deaminase
---------------------|----|||||----|||----|||||-||||-|||---|||||--  2 [K] COG2186 Transcriptional regulators
|-||----|-----|-||||-|-----||||---|-||----|||---||-----|---|||||--  2 [T] COG2203 FOG: GAF domain
----------------||-|-|--||----|------|----------||-----|---|--|---  2 [T] COG2206 HD-GYP domain
--|-----------|-----|---------|----||||---|||||-||||-||||||-|-||--  2 [R] COG2249 Putative NADPH-quinone reductase (modulator of drug activity B)
-|-|--||------|--|||||--|||---||||||||-|--|||||-||||-||||||-||-|--  2 [R] COG2252 Permeases
-------||----||--|-|||----||||||--||||----|||||-||||---|---|||||--  2 [I] COG2267 Lysophospholipase
------------------||----------||-|--||||||-||||-||--||||----|-||--  2 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
-||---------------||-|---|-||--|--|-||-----------|-----|----------  2 [S] COG2314 Predicted membrane protein
--|---------------|-||--------------||----|||||-||---|||---|||||--  2 [R] COG2334 Putative homoserine kinase type II (protein kinase fold)
----||||--|||----|---|---------------------------|-----|---||||---  2 [G] COG2379 Putative glycerate kinase
||||--|||||||-|--|------------------------|||||-||--||||||||||||--  2 [O] COG2518 Protein-L-isoaspartate carboxylmethyltransferase
--|-----------------|-----|---|-|-|-||----|||||-||||-|||----------  2 [GE] COG2610 H+/gluconate symporter and related permeases
--------------|---------------||-||||-----||||||-|-----|----------  2 [G] COG2706 3-carboxymuconate cyclase
----|------|------------------|-----||----|||||--------|--||||||--  2 [G] COG2721 Altronate dehydratase
-----------|-||---||-------|||||||-|||----|||||-||-|-|||--||||||--  2 [E] COG2755 Lysophospholipase L1 and related esterases
--------------------|---------------------|||||-||||||||--|----|||  2 [M] COG2853 Surface lipoprotein
-------------||-|-------------------||----------||--||||||||||||||  2 [C] COG2857 Cytochrome c1
-|--------------|---|---------------------||||||-|||-||||||---||--  2 [M] COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase
-----------------|------------------------|||||-|||||||||||||-||--  2 [S] COG2908 Uncharacterized protein conserved in bacteria
----------------------------------------------------|--|||-|||||||  2 [U] COG2948 Type IV secretory pathway, VirB10 components
--------------------------|||-------------|||||-||-|||||---|||||--  2 [M] COG2951 Membrane-bound lytic murein transglycosylase B
---|||--------------||----------|-|-||-------||-||-----|---|||||--  2 [E] COG2986 Histidine ammonia-lyase
------------------------------------------------||---|||||||||||--  2 [C] COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit
------------------------------------------|||||-|-||-|||----------  2 [S] COG2995 Uncharacterized paraquat-inducible protein A
------------------------------------------|||||-||||-|||----------  2 [R] COG3008 Paraquat-inducible protein B
--------------------|---------------------|||||-||||||||---|||||-|  2 [V] COG3023 Negative regulator of beta-lactamase expression
------------------|-----------------------|||||-||-||-||---|||||-|  2 [C] COG3038 Cytochrome B561
------------------------------------------|||||-||-||--|---|-|||||  2 [M] COG3047 Outer membrane protein W
------------------|--|--------------------|||||--|--|--|---||-|--|  2 [NU] COG3121 P pilus assembly protein, chaperone PapD
----------------------------------||||----||||||-|--|--|---|-|||--  2 [C] COG3125 Heme/copper-type cytochrome/quinol oxidase, subunit 4
------------------------------------------|||||-||-----|----------  2 [NT] COG3143 Chemotaxis protein
--|-----------------------|----||---------|||||-||--|--|---|||||--  2 [P] COG3158 K+ transporter
------------------------------------------------||--||||----------  2 [NU] COG3170 Tfp pilus assembly protein FimV
--------------------|-----|---------||--------|-||-|---|---||-----  2 [S] COG3181 Uncharacterized protein conserved in bacteria
------------------|-----------------------|||||--|--|--|---|--|--|  2 [NU] COG3188 P pilus assembly protein, porin PapC
------------------------------------------------||---|||-------|--  2 [C] COG3245 Cytochrome c5
---------------------------||-------|------|--|--|-----|---|------  2 [S] COG3251 Uncharacterized protein conserved in bacteria
-------------||----|-|----|---------------|||||-||-|-|||---||-|---  2 [G] COG3265 Gluconate kinase
------------------------------------------------||---|||||||||||--  2 [O] COG3278 Cbb3-type cytochrome oxidase, subunit 1
-----------------||||---------|--||-------|||||-||||||||||-|||||||  2 [M] COG3307 Lipid A core - O-antigen ligase and related enzymes
------------------------------------------|||||-|---|--|----|||---  2 [K] COG3311 Predicted transcriptional regulator
------------------------------------------|||||-||-----|----||||--  2 [R] COG3313 Predicted Fe-S protein
--|-||-----|------|--------||-||-----||----||||--------|----|-|---  2 [L] COG3328 Transposase and inactivated derivatives
---|-------|-------|------|||--||--|-------|||------|--|----------  2 [R] COG3378 Predicted ATPase
-----------|---------|---------------|----|------------|----|-----  2 [S] COG3396 Uncharacterized conserved protein
---|------------||||-|---------------|-----------------|----------  2 [C] COG3411 Ferredoxin
-----------|--------------|----------|-----||-|--|-----|----------  2 [Q] COG3435 Gentisate 1,2-dioxygenase
------------------------------|----|||----|||-|--------|------||--  2 [L] COG3449 DNA gyrase inhibitor
--|--|-------------||-----|||----||--|-----------------|---||-|---  2 [L] COG3464 Transposase and inactivated derivatives
---------------------|---------------------------|-----|------||--  2 [E] COG3483 Tryptophan 2,3-dioxygenase (vermilion)
--------------------------|------------------|---|-----|---|||||||  2 [Q] COG3485 Protocatechuate 3,4-dioxygenase beta subunit
---|----------|----|-----------------|-------|---|-----|----|-|---  2 [Q] COG3486 Lysine/ornithine N-monooxygenase
-----------|---------------||--------------------|-----|------||--  2 [M] COG3511 Phospholipase C
---------------------------------------------|--||-----|------|---  2 [O] COG3531 Predicted protein-disulfide isomerase
---------------------|------------|-||-----------|-----|---|||||--  2 [R] COG3545 Predicted esterase of the alpha/beta hydrolase fold
--------------------------------||-|------|||-|--|--|--|---|||||--  2 [R] COG3568 Metal-dependent hydrolase
-------------||-----|-----|||--------------------|-----|---|||||--  2 [E] COG3616 Predicted amino acid aldolase or racemase
--------------------------|---------------|||||--|||---|----|||---  2 [G] COG3622 Hydroxypyruvate isomerase
--||--||---|------|-----------|-----------|||||--------|----------  2 [L] COG3677 Transposase and inactivated derivatives
------------------------------------------|------|-----|---||--|--  2 [PT] COG3712 Fe2+-dicitrate sensor, membrane component
-------------------------------------------------|-----|---||-||--  2 [U] COG3745 Flp pilus assembly protein CpaB
-------------------------------------------------|-----|---|||||--  2 [S] COG3749 Uncharacterized protein conserved in bacteria
--------------------------|----|-|||--------------|--|||---|--|---  2 [S] COG3759 Predicted membrane protein
-------------------|----------|-----------|||||-----|--|------||-|  2 [R] COG3772 Phage-related lysozyme (muraminidase)
----------------|----|--------|------------------|-----|----------  2 [S] COG3868 Uncharacterized conserved protein
---------------------------------------------|---|-----|---||-|---  2 [TQ] COG3916 N-acyl-L-homoserine lactone synthetase
-------------------|----------||----|------------------|---||-----  2 [M] COG3967 Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
---|---------||---||||----|||--|-|||------|||-|-||||||||||||||----  2 [R] COG4221 Short-chain alcohol dehydrogenase of unknown specificity
|-|-|||||-||------------------|------------------------|------||--  2 [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits
------------------|------------------------------|-----|----------  2 [V] COG4257 Streptogramin lyase
-------------------------------------------||-------|--|----------  2 [R] COG4258 Predicted exporter
-------------------------------------------||-------|--|----------  2 [R] COG4261 Predicted acyltransferase
----------------|---------|||--------------------------|----------  2 [R] COG4262 Predicted spermidine synthase with an N-terminal membrane domain
-----|-------------------------------------------------|----|-|---  2 [S] COG4275 Uncharacterized conserved protein
---------------------------|-|-------------------------|-------|--  2 [Q] COG4308 Limonene-1,2-epoxide hydrolase
-------------------------------------------------|-----|---||||---  2 [E] COG4311 Sarcosine oxidase delta subunit
-------------------|----------------|------------|-----|----|-|---  2 [S] COG4319 Ketosteroid isomerase homolog
---------------------|---------|-|||-|----------||-----|----------  2 [S] COG4392 Predicted membrane protein
-------------------------------------------------|-----|---||||---  2 [E] COG4583 Sarcosine oxidase gamma subunit
--|||||||-|||---||--||||-||---||||||||-||||||||-||||---||||||||---  2 [E] COG4608 ABC-type oligopeptide transport system, ATPase component
-------------------------------------------||||-----|--|----------  2 [S] COG4643 Uncharacterized protein conserved in bacteria
-------------------------------------------||---------||----------  2 [S] COG4648 Predicted membrane protein
----------------|--------------------------------|-----|----------  2 [C] COG4654 Cytochrome c551/c552
------------------------------------------|||----|-----|----------  2 [S] COG4676 Uncharacterized protein conserved in bacteria
-------------------------------------------||------|---|----------  2 [S] COG4688 Uncharacterized protein conserved in bacteria
-------------------|-----------------------------------|------|---  2 [S] COG4705 Uncharacterized membrane-anchored protein conserved in bacteria
-------------------------------------------||--------|-|----------  2 [I] COG4706 Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase
------------------------||-----------------------------|||-|||||--  2 [S] COG4731 Uncharacterized protein conserved in bacteria
--|----------|||---|----------|-|--|------|||||--|-----|----------  2 [S] COG4886 Leucine-rich repeat (LRR) protein
---------------------------------------------|---|-|---|---||-||--  2 [OU] COG4960 Flp pilus assembly protein, protease CpaA
---------------------------------------------|---|-|---|---||-||--  2 [U] COG4961 Flp pilus assembly protein TadG
---------------------------------------------|---|-|---|---||-||--  2 [U] COG4963 Flp pilus assembly protein, ATPase CpaE
---------------------|---------------------------|-|---|---||-||--  2 [U] COG4964 Flp pilus assembly protein, secretin CpaC
--------------------------|||----------------|---|-|---|---||-||--  2 [U] COG4965 Flp pilus assembly protein TadB
----------------|-------------------------|||||-||||||||----------  2 [NU] COG4969 Tfp pilus assembly protein, major pilin PilA
--------------------|---|-|||||---||||----|||||-||||||||---|||||||  2 [L] COG4974 Site-specific recombinase XerD
--------------|----------------------------------------|-----|-|--  2 [F] COG5042 Purine nucleoside permease
-------------------------------------------||||--|-----|---|-|----  2 [S] COG5281 Phage-related minor tail protein
----------------||-------|--------||||----|||||||||||--|||||||||||  2 [O] COG5405 ATP-dependent protease HslVU (ClpYQ), peptidase subunit
-------------------------------------------||||--|-----|----------  2 [S] COG5435 Uncharacterized conserved protein
------------------------------------------|||----|-----|----------  2 [S] COG5445 Predicted secreted protein
-------------------------------------------|--|--------|-----|-|-|  2 [S] COG5510 Predicted small secreted protein
------------------||----|--||-------||-----------------|---||-|---  2 [K] COG5662 Predicted transmembrane transcriptional regulator (anti-sigma factor)
|||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||--  1 [E] COG0002 Acetylglutamate semialdehyde dehydrogenase
|||-||--||-|-||-||||-|----|||-||--|||||---|||||--|--||||---|||||--  1 [P] COG0004 Ammonia permease
|||||||||||||||||||||||||||||||||||||||||||||||-||||||||||||||||||  1 [E] COG0006 Xaa-Pro aminopeptidase
||||||--|||||||-|-||||----|||||---||||----||||||||--||||---|||||--  1 [H] COG0007 Uroporphyrinogen-III methylase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0012 Predicted GTPase, probable translation factor
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0013 Alanyl-tRNA synthetase
--|----------||-||||-|--|-||||||||-|||----|||||-||||||||--||||||--  1 [E] COG0014 Gamma-glutamyl phosphate reductase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0016 Phenylalanyl-tRNA synthetase alpha subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0018 Arginyl-tRNA synthetase
||||||||||||||||||||||||||||||||||||||----||||||||||||||||||||||||  1 [I] COG0020 Undecaprenyl pyrophosphate synthase
-------------|||||||-||||-||||||||||||||||||||||||||||||||||||||--  1 [G] COG0021 Transketolase
---|||----||||||--||-|||---||--|||||||-|||-------|-----|---|||||||  1 [C] COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
||||||||||||||||||||||||||||||-|||||||||||||||||||||||||||||||||||  1 [J] COG0024 Methionine aminopeptidase
---|||----||-||-||||-|----||||-|||||||----|||||-||||||||---|||||--  1 [F] COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0030 Dimethyladenosine transferase (rRNA methylation)
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase
|--|---|--|||||-||||||--|-|||-|||||||||||||||||-||||-|||--||||||--  1 [F] COG0035 Uracil phosphoribosyltransferase
-|--||-------||||||||||||-||||||||||||||||||||||||||||||||||||||--  1 [G] COG0036 Pentose-5-phosphate-3-epimerase
||||||--|||||||-||||||||-|||||||||||||-||||||||-|-|||--|--||||||||  1 [C] COG0039 Malate/lactate dehydrogenases
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase
|||-||||||||||--|-||-|||------------||----|||||-||-|-|||||||||-|||  1 [H] COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases
|||||||||||||||-||||||----||||||||||||----|||-|--|--|--|||||||||--  1 [F] COG0044 Dihydroorotase and related cyclic amidohydrolases
||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||--||||||||  1 [C] COG0045 Succinyl-CoA synthetase, beta subunit
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0048 Ribosomal protein S12
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0049 Ribosomal protein S7
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0051 Ribosomal protein S10
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0052 Ribosomal protein S2
||||---||||||||-||||||---||||-||||||||----|||||-||-|---|--||||||||  1 [P] COG0053 Predicted Co/Zn/Cd cation transporters
||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG0054 Riboflavin synthase beta-chain
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0055 F0F1-type ATP synthase, beta subunit
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0056 F0F1-type ATP synthase, alpha subunit
||||||||||||||||||||||||||||||||||||||-|||||||||||||||||||||||||--  1 [G] COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase
|||----|||||-|--||||-|----||||||-|||||----||||||||||||||||||||||--  1 [EH] COG0059 Ketol-acid reductoisomerase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0060 Isoleucyl-tRNA synthetase
|||||||||||||||||||||---|||||||||||||||-||||||||||||||||||||||||||  1 [G] COG0061 Predicted sugar kinase
|||||||||||||||-||||-|----|||||-----------|||||-||--|--|||||||||--  1 [S] COG0062 Uncharacterized conserved protein
||||||||||||||||||||-|----||||||--|||-----|||||-||--||||||||||||--  1 [G] COG0063 Predicted sugar kinase
||||----||-||||-||||||||||||||||||||||||||-------|---|||||||||||||  1 [J] COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog)
||||--||||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0065 3-isopropylmalate dehydratase large subunit
|||---||||||-||-||||-|----||||||-|||||----||||||||||||||--||||||--  1 [E] COG0066 3-isopropylmalate dehydratase small subunit
|||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||--  1 [E] COG0067 Glutamate synthase domain 1
|||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||--  1 [E] COG0070 Glutamate synthase domain 3
|||||||||||||||-||||-|-----||||---|-||----||||||||--|--|---|||||||  1 [O] COG0071 Molecular chaperone (small heat shock protein)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0072 Phenylalanyl-tRNA synthetase beta subunit
||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||--||||||||  1 [C] COG0074 Succinyl-CoA synthetase, alpha subunit
||||||--||||-||-||||-|----||||||-|||||----|||-||||||||||--||||||--  1 [E] COG0077 Prephenate dehydratase
|||||||||||||||-||||-|---|||||||||||||--|-||||||||||||||--||||||--  1 [E] COG0078 Ornithine carbamoyltransferase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0080 Ribosomal protein L11
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0081 Ribosomal protein L1
||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||--  1 [E] COG0082 Chorismate synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0087 Ribosomal protein L3
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0088 Ribosomal protein L4
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0089 Ribosomal protein L23
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0090 Ribosomal protein L2
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0091 Ribosomal protein L22
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0092 Ribosomal protein S3
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0093 Ribosomal protein L14
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0094 Ribosomal protein L5
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0096 Ribosomal protein S8
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0097 Ribosomal protein L6P/L9E
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0098 Ribosomal protein S5
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0099 Ribosomal protein S13
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0100 Ribosomal protein S11
|||||||||||--||||||||||||||||||||||||||-||||||||||||||||||||||||||  1 [J] COG0101 Pseudouridylate synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0102 Ribosomal protein L13
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0103 Ribosomal protein S9
||||||||||||-||-||||||----||||||||||||----||||||||||||||||||||||--  1 [F] COG0104 Adenylosuccinate synthase
|||||||||||||||||-||-||||||||||--|||||----|||||-||||||||||||||||||  1 [F] COG0105 Nucleoside diphosphate kinase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0107 Imidazoleglycerol-phosphate synthase
---|||--|-|||||-|-||-|----||||----||||----||||||-|--|--|---|||||||  1 [O] COG0109 Polyprenyltransferase (cytochrome oxidase assembly factor)
||||||--|||||||-|-||||||--|||||---||||----|||||-||-|||||||||||||||  1 [H] COG0113 Delta-aminolevulinic acid dehydratase
--||------|||||---|--|||--||||----||||----|||||-||||||||||||||||||  1 [C] COG0114 Fumarase
-|----|||||-|-----|-||--------||||||||----||||||||||||||----------  1 [L] COG0116 Predicted N6-adenine-specific DNA methylase
-------------||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG0117 Pyrimidine deaminase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0118 Glutamine amidotransferase
||||||||||||||||--||-|||||----||||||------||||||||||||||---|||||--  1 [G] COG0120 Ribose 5-phosphate isomerase
||--|-||--||-|----||-------||-------------|||||-||||-|||---||||---  1 [R] COG0121 Predicted glutamine amidotransferase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0124 Histidyl-tRNA synthetase
||||||||||||||||||||||||||||||-|||||||||||||||||||||||||||||||||||  1 [F] COG0125 Thymidylate kinase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||--  1 [G] COG0126 3-phosphoglycerate kinase
||||||||||||||||||||||||||||||||||||||----|||||-||||||||--||||||--  1 [F] COG0127 Xanthosine triphosphate pyrophosphatase
||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||--  1 [E] COG0128 5-enolpyruvylshikimate-3-phosphate synthase
||||||||||||||||||||||||||||||||||||||||--||||||||||||||--||||||||  1 [J] COG0130 Pseudouridine synthase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0131 Imidazoleglycerol-phosphate dehydratase
-|-----------|--|-|||--|--|||||---|-||----||||||||||||||||||-|||--  1 [H] COG0132 Dethiobiotin synthetase
||||---|||---||-|||||||---||||||-|||||----||||||||||||||||||||||--  1 [E] COG0133 Tryptophan synthase beta chain
||||||-||||||||-||||-||---|---||-|||||----||||||||||||||||||||||--  1 [E] COG0135 Phosphoribosylanthranilate isomerase
|||||-|||||||||-||||-|||--||||||-|||||----||||||||||||||||||||||||  1 [E] COG0136 Aspartate-semialdehyde dehydrogenase
||||||--||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0137 Argininosuccinate synthase
--||||--|----||-||||||----||||||-|||||----||||||||||||||--||||||--  1 [F] COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0139 Phosphoribosyl-AMP cyclohydrolase
||||-----|||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0140 Phosphoribosyl-ATP pyrophosphohydrolase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0141 Histidinol dehydrogenase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||--  1 [G] COG0148 Enolase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||--  1 [G] COG0149 Triosephosphate isomerase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0150 Phosphoribosylaminoimidazole (AIR) synthetase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||||||||||--  1 [F] COG0151 Phosphoribosylamine-glycine ligase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||||  1 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase
||||--||||||-|--|||||-----|||||-||-|||----|||||-||||||||||-||-||--  1 [H] COG0157 Nicotinate-nucleotide pyrophosphorylase
---|---------||---||----------------------|||||-||||-||||||-||-|--  1 [G] COG0158 Fructose-1,6-bisphosphatase
||||||-||||||||-||||-||---||||||-|||||----||||||||||||||||||||||--  1 [E] COG0159 Tryptophan synthase alpha chain
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0162 Tyrosyl-tRNA synthetase
|||-||||||||||--|-||-|||------------||----|||||-||-|-|||||||||-|||  1 [H] COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase
||||||||||||||||||||||||-|||||||||||||----|||||-||||||||||||||||||  1 [L] COG0164 Ribonuclease HII
||||||--||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0165 Argininosuccinate lyase
|||||||||||||||-||||||----||||||||||||----||||||||||||||||||||||--  1 [F] COG0167 Dihydroorotate dehydrogenase
|||||||||||||||-||||||--||||||||||||||||||||||||||--||||||||||||--  1 [H] COG0171 NAD synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0172 Seryl-tRNA synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0173 Aspartyl-tRNA synthetase
-|--||-------||-||||-|||--|||||-||||||----||||||||||-|||||||||||--  1 [G] COG0176 Transaldolase
||||||||||||||||||||||||||||||||||||||----||||||||||||||||||||||||  1 [L] COG0177 Predicted EndoIII-related endonuclease
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0180 Tryptophanyl-tRNA synthetase
||||||--|||||||-|-||||||--|||||---||||----||||||||-|||||||||||||||  1 [H] COG0181 Porphobilinogen deaminase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0184 Ribosomal protein S15P/S13E
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0185 Ribosomal protein S19
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0186 Ribosomal protein S17
-|||--|||-|||-----||-|---------------|--||||||||||||||||---|||||--  1 [HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)
--||||----||-||-|||||||||||||||||||||||||||||||||||||-||||||||||||  1 [H] COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase
-------------||-||||-|--||||||||||||||||||||||||||||-||||||-||||--  1 [G] COG0191 Fructose/tagatose bisphosphate aldolase
-------------||-||||||--||||||||||||||||||||||||||||||||||||||||--  1 [H] COG0192 S-adenosylmethionine synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0193 Peptidyl-tRNA hydrolase
-------------|||||||||||--||||||||||||||||||||||||||||||||||||||||  1 [F] COG0194 Guanylate kinase
|||||||||||||---||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0195 Transcription elongation factor
-------------||-|||||||||-||||||||||||||||||||||||||||||||||||||--  1 [H] COG0196 FAD synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0197 Ribosomal protein L16/L10E
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0198 Ribosomal protein L24
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0199 Ribosomal protein S14
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0200 Ribosomal protein L15
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0201 Preprotein translocase subunit SecY
||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0203 Ribosomal protein L17
||||||||||------||||||--||||||||||||||-|||||||||||||||||||||||||||  1 [D] COG0206 Cell division GTPase
|||-----||---|||----||----||||||||||||-|||||||||||||||||---|||||--  1 [F] COG0207 Thymidylate synthase
---|-------|-||||-|-|||||-||||||||||||-|||||||||||||||||||||-|-|||  1 [F] COG0208 Ribonucleotide reductase, beta subunit
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0211 Ribosomal protein L27
|--|-----||||||-|-|||||||-||||||-|||||--|||||||-||||||||||||||||||  1 [H] COG0212 5-formyltetrahydrofolate cyclo-ligase
-||---|||--------|---|-----||-||-||||||||||||-|-|------|---||-|---  1 [F] COG0213 Thymidine phosphorylase
--|||||||-||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0215 Cysteinyl-tRNA synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0216 Protein chain release factor A
-------------||-|||||||||||||||||||||||||||||||-||||||||||||||||||  1 [S] COG0217 Uncharacterized conserved protein
-|||--||||---|--||--|---------||||||||||||||||||||||||||||||||||||  1 [R] COG0218 Predicted GTPase
------------------||||||--|||||||||-|||||||||||-||||||||--||||||--  1 [J] COG0219 Predicted rRNA methylase (SpoU class)
-------------||||||||||||-||||||||||||||||||||||||||||||||||||||||  1 [R] COG0220 Predicted S-adenosylmethionine-dependent methyltransferase
|-||||||-|-||||||-||||||--|||||----|-|||||||||||||||||||||||||||||  1 [C] COG0221 Inorganic pyrophosphatase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0222 Ribosomal protein L7/L12
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0224 F0F1-type ATP synthase, gamma subunit
|-||-------|-||---||||--|-|||||||||||||||||||||-||||||||||||||||--  1 [O] COG0225 Peptide methionine sulfoxide reductase
-------------||-|||||||||||||-|||||||||||||||||||||||||||||-||||||  1 [J] COG0227 Ribosomal protein L28
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0228 Ribosomal protein S16
|-||---------||---||||--|-|||-||||||||-||||||||-||||||||||||||||--  1 [O] COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase
-------------||-||||-||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0230 Ribosomal protein L34
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)
------------------|--|----||||-----|------|||||-||||---|---|||||||  1 [F] COG0232 dGTP triphosphohydrolase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0233 Ribosome recycling factor
--|----------||-||||||||||||||||||||||--||||||||||||||||||||||||||  1 [O] COG0234 Co-chaperonin GroES (HSP10)
||||||||||||||||||||||||||||||||||||||-|||||||||||||||||||||||||||  1 [H] COG0237 Dephospho-CoA kinase
-------------||-|||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0238 Ribosomal protein S18
-|||--||-|---||-||||-|----|||-|--|||||----|||||-||||||||||||||||--  1 [D] COG0239 Integral membrane protein possibly involved in chromosome condensation
|-------|----|||||||||||||||||||||||||||--|||||-||||||||||||||||||  1 [C] COG0240 Glycerol-3-phosphate dehydrogenase
-|--||-------|||--|-|------||-|-----------|||||||||||||||||---||--  1 [E] COG0241 Histidinol phosphatase and related phosphatases
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0244 Ribosomal protein L10
----------------|||||||||-|||||----|||--||||||||||||||||||||||||--  1 [I] COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
-------------|---|--------|---||-||-||-||-||||||||-|---|---|||||--  1 [G] COG0246 Mannitol-1-phosphate/altronate dehydrogenases
--|--------|-|--||||||----|||||------|----|||||-||||||||||||||||||  1 [FP] COG0248 Exopolyphosphatase
--||-|-------|||||||||||||----|||-||||----||||||||||||||---|||||||  1 [L] COG0249 Mismatch repair ATPase (MutS family)
|||||||||||||-|-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0250 Transcription antiterminator
|||||||||||||||-----||----||||||||||||----|||||-|||-||||||||-|----  1 [EJ] COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D
||------||------|||||-||--|||||---||||----||||||||||||||||||||||||  1 [E] COG0253 Diaminopimelate epimerase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0254 Ribosomal protein L31
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0255 Ribosomal protein L29
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0256 Ribosomal protein L18
-------------||-||||-||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0257 Ribosomal protein L36
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0258 5'-3' exonuclease (including N-terminal domain of PolI)
------------|-|||-||||||--||||----|-|||||||||||||||||-||||||||||||  1 [E] COG0260 Leucyl aminopeptidase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0261 Ribosomal protein L21
--|----------|||-|--||||--||||||||||||||||||||||||||||||---|||||-|  1 [H] COG0262 Dihydrofolate reductase
--|----------||-||||-|--|-||||||||-|||----|||||-||||||||--||||||--  1 [E] COG0263 Glutamate 5-kinase
--------------|-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0264 Translation elongation factor Ts
------------------||-|----||||-||||||||||||||||-||||||||---|||||-|  1 [L] COG0266 Formamidopyrimidine-DNA glycosylase
-------------||-|||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0267 Ribosomal protein L33
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0268 Ribosomal protein S20
---|---------||---||----------------------||||||||||||||---|||||||  1 [T] COG0271 Stress-induced morphogen (activity unknown)
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0272 NAD-dependent DNA ligase (contains BRCT domain type II)
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [M] COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis
----||-------||-|-||-|||--||||-|-|||||----|||||-||||||||||||||||||  1 [H] COG0276 Protoheme ferro-lyase (ferrochelatase)
---|---------|||--||----------------------||||||||||||||---|||||||  1 [O] COG0278 Glutaredoxin-related protein
---------------||||||||||||||||||||||||||||||||-||||||||---|||||||  1 [F] COG0283 Cytidylate kinase
|||||||||||||||-||||||----||||||||||||----||||||||||||||||||||||--  1 [F] COG0284 Orotidine-5'-phosphate decarboxylase
---|||-------||-||||||--|-||||||||||||----||||||||||||||||||||||||  1 [H] COG0285 Folylpolyglutamate synthase
||||---||----------|-------||--|||||--|||-|||-|-|||||||||||-||-|-|  1 [V] COG0286 Type I restriction-modification system methyltransferase subunit
||||||--|||||||-||||-|----||||||-|||||----|||||-||||||||||||||||--  1 [E] COG0287 Prephenate dehydrogenase
|||-----||------||||--||--|||-||-|||||----||||||||||||||||||||||||  1 [E] COG0289 Dihydrodipicolinate reductase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0290 Translation initiation factor 3 (IF-3)
-------------|--||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0291 Ribosomal protein L35
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0292 Ribosomal protein L20
||||||--||---|||--------||----------------||||||||||||||---|||||||  1 [J] COG0293 23S rRNA methylase
|||||||||||||||-||||||||--||||||||||||----|||||-||||||||||||||||-|  1 [H] COG0294 Dihydropteroate synthase and related enzymes
-|----||--||--|-||||||||------||-|--||----|||||-||||---|---||-|---  1 [G] COG0297 Glycogen synthase
--||||----|--||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN
--|----|---|-|||---||-----||||||||||||-----------|-|---|---||-||--  1 [R] COG0300 Short-chain dehydrogenases of various substrate specificities
----------||-||-|-||||----||||||||-|||----|||||-|||||--|||||||||||  1 [H] COG0302 GTP cyclohydrolase I
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0305 Replicative DNA helicase
||||||||||||-|---|-|-|||--|||||---||||----||||||||||-||||||||-|---  1 [P] COG0306 Phosphate/sulphate permeases
---|---------||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG0307 Riboflavin synthase alpha chain
|||||||||-|||---|-||-|----|||-----||||----|||||-||||---|||||||||--  1 [H] COG0314 Molybdopterin converting factor, large subunit
|||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||--  1 [H] COG0315 Molybdenum cofactor biosynthesis enzyme
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [R] COG0319 Predicted metal-dependent hydrolase
---|------|||||-|-||-|||--||||----|-||----||||||||||||||---|||||||  1 [H] COG0320 Lipoate synthase
----------|--||---||-|----||||------------||||||||||||||---|||||||  1 [H] COG0321 Lipoate-protein ligase B
|-||------------|||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG0322 Nuclease subunit of the excinuclease complex
--||---------|||||||||||||----||||||||----||||||||||||||---|||||||  1 [L] COG0323 DNA mismatch repair enzyme (predicted ATPase)
-------------|||--|||---|||||||----|||----|||||||||||--||||-|-|-||  1 [O] COG0326 Molecular chaperone, HSP90 family
||||--||||---|||---|||||||||-|||||||||||--||||||||||-||||||-------  1 [S] COG0327 Uncharacterized conserved protein
---|------|--||---||-|--|-||||----||||----|||||-||||||||||||||||||  1 [L] COG0328 Ribonuclease HI
-------------||-||||||||--||||||||||||----|||||-||||||||||||||||||  1 [I] COG0331 (acyl-carrier-protein) S-malonyltransferase
-------------||-||||||||||----||||||||||||||||||||||||||||||||||||  1 [J] COG0333 Ribosomal protein L32
--|||||||-|||||--|||||||--|---|--|||||----|||||--|||-|||||--||-|--  1 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0335 Ribosomal protein L19
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0336 tRNA-(guanine-N1)-methyltransferase
----||-|--|||||--|||||||--||||||||||||----||||||||||||||||||||||--  1 [E] COG0337 3-dehydroquinate synthetase
-------------||---||-|----|---------------|||||-||||||||---|||||--  1 [E] COG0339 Zn-dependent oligopeptidases
||||--|||--|-||-|||||||||-||||||||||||----|||||-||||||||||||||||||  1 [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase
||||--||-|------|||||||||||||||---||||-|--|||||-||||||||||||||||||  1 [U] COG0341 Preprotein translocase subunit SecF
||||--||-|------|||||||||||||||---||||-|--|||||-||||||||||||||||||  1 [U] COG0342 Preprotein translocase subunit SecD
|||||||||||||-||||||||||-||---||||||||----||||||||||||||||||||||||  1 [J] COG0343 Queuine/archaeosine tRNA-ribosyltransferase
----------------||||||--------|||||||||||||||||-||||-|||||||||||--  1 [S] COG0344 Predicted membrane protein
|-|-||----|||||-||||-|--|-||||||||||||----|||||-||||||||||||||||--  1 [E] COG0345 Pyrroline-5-carboxylate reductase
|||||||||||||||-||-|||--|-||||||||||||----|||||-||||||||||||||||--  1 [H] COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase
----------------|-|||||||-||||||||||||||--|||||-||||||||||||||||||  1 [L] COG0353 Recombinational DNA repair protein (RecF pathway)
-------------||-|-||-|----||||------------||||||||||||||---|||||||  1 [R] COG0354 Predicted aminomethyltransferase related to GcvT
--|----------|--|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0356 F0F1-type ATP synthase, subunit a
----------------||||||--|||||||||||||||||||||||-||||||||||||||||||  1 [M] COG0357 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division
--------------|-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0359 Ribosomal protein L9
-------------||-|||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0360 Ribosomal protein S6
-------------|||-||||-||||||||||||||||-|--|||||-||||||||||-|||||--  1 [G] COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase
-------------|||||||-||||||||--|-||||-----||||||||||||||||-|||||--  1 [G] COG0364 Glucose-6-phosphate 1-dehydrogenase
|||||||||||||-----||||----|||-|----|-|----|||-|-||-----|---||||---  1 [H] COG0368 Cobalamin-5-phosphate synthase
|||---|||||-----||||-|--------||--||------|||||-||--|--||||----|--  1 [P] COG0370 Fe2+ transport system protein B
||||||--|||||---|-||||||--|||||---||||----|||||-||-||||||||-------  1 [H] COG0373 Glutamyl-tRNA reductase
--|||||||-|||---||||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases
|||-----||----|-|-||||----|||-----|--||---|||||--||----||||||||---  1 [OK] COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase
||||--||||||----|||||-----|||||----|||----|||||-||--||||||-||-||--  1 [H] COG0379 Quinolinate synthase
--||---------||---||||----|||-|----|||----|||-|-||-|---|---|||||--  1 [R] COG0384 Predicted epimerase, PhzC/PhzF homolog
--|----------|--|-||------|--|----|-||----|||||--|---|||---|||||--  1 [R] COG0385 Predicted Na+-dependent transporter
-||-------------||||-------||-----|-|-----|||-|--------|----------  1 [R] COG0390 ABC-type uncharacterized transport system, permease component
||||--||||------||||------|||||---|||-|||||||-|--|--|--|---||||---  1 [S] COG0392 Predicted integral membrane protein
-------------||---||------|----------|----|||-|-||--|--|---||--|--  1 [S] COG0397 Uncharacterized conserved protein
---|||||---||||-||||-|-----|||----||||----|||||--|--|-||---|||||--  1 [E] COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain
--|-||-------||-|-||-|||--||||----||||----|||||-||-|||||||||||||||  1 [H] COG0407 Uroporphyrinogen-III decarboxylase
-------------||---||----------------------|||||-||--|--|---|||||||  1 [H] COG0408 Coproporphyrinogen III oxidase
---|--||--|||||-||||-|----|||||---||||----||||||||--||||||||||||--  1 [H] COG0413 Ketopantoate hydroxymethyltransferase
-------------||-||||-|----|||||---||||----||||||||--||||||||||||--  1 [H] COG0414 Panthothenate synthetase
----------------||||||||------|||||||||||||||||-||-|-|||||||||||--  1 [I] COG0416 Fatty acid/phospholipid biosynthesis enzyme
-------------||---|-----------------------||||||||---||||||||-----  1 [F] COG0418 Dihydroorotase
||||---|||||----||||||----|||||-----||----|||||-||--||||--|||-||--  1 [H] COG0422 Thiamine biosynthesis protein ThiC
||||||--||||----|||||-------------|-|-----||||||||||-|||--||||||--  1 [O] COG0425 Predicted redox protein, regulator of disulfide bond formation
|||---|||-------|||||---------|-----------|||-|--|-----|----------  1 [C] COG0426 Uncharacterized flavoproteins
||||--||--||||||||-|-|---||||------|------|||-|--|---|||--|-|-----  1 [P] COG0428 Predicted divalent heavy-metal cations transporter
-------------|-|--||----------------------|||||-||---|||----------  1 [R] COG0429 Predicted hydrolase of the alpha/beta-hydrolase fold
||||--|||||||||||--|----------------------|||-|--|-----|----------  1 [A] COG0430 RNA 3'-terminal phosphate cyclase
|||||||||||||---||||-|-----||---|----|----||||---|-|---|---|||||--  1 [R] COG0433 Predicted ATPase
--||---||-|||---|-------------------------|||||-||||---|--|-|-|---  1 [C] COG0437 Fe-S-cluster-containing hydrogenase components 1
|||---||||--|||-||||-|----||||||-|||||----||||||||||-|||--||||||--  1 [E] COG0440 Acetolactate synthase, small (regulatory) subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0441 Threonyl-tRNA synthetase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0442 Prolyl-tRNA synthetase
-------------||-||||||||||----||||||||||||||||||||||||||||||||||||  1 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division
||||||||-||||||||||||||||-||||||||||||----||||||||||||||||||||||--  1 [M] COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains
|||||||||||||||-||||||---|||||||||||||----|||||-||||||||||||||||--  1 [H] COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase
||-|--||||------||-|----||-||||-----||----------||-----||||-------  1 [D] COG0455 ATPases involved in chromosome partitioning
||||||--||||-||-||||||----||||||||||||----||||||||-|||||||||||||--  1 [EF] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
||||||||||||||||||||||||||||||||||||||--||||||||||||||||||||||||||  1 [O] COG0459 Chaperonin GroEL (HSP60 family)
|||||||||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1 [E] COG0460 Homoserine dehydrogenase
|||||||||||||||-||||||-|--||||||||||||----||||||||||||||||||||||--  1 [F] COG0461 Orotate phosphoribosyltransferase
||||||||||||||||--||-|----||||------||-----------|-----|--|||-|---  1 [O] COG0464 ATPases of the AAA+ class
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0465 ATP-dependent Zn proteases
--|----------||-||--||||||----|-----||||||||||||||||||||||||||||||  1 [O] COG0466 ATP-dependent Lon protease, bacterial type
|||||||||||||||||||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG0468 RecA/RadA recombinase
|||||||||||||||||||||||||-||||-|||||||||||||||||||||||||||||||||||  1 [L] COG0470 ATPase involved in DNA replication
||-|--||-||--||-|-|--|||--|---|||||-||----|||||-||||||||||||||----  1 [P] COG0471 Di- and tricarboxylate transporters
|-|||||||-|||||||-||||----|||||--|||||----|||||-||||||||||||||||--  1 [H] COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||||||||||||  1 [C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [M] COG0481 Membrane GTPase LepA
-------------||-||||||||-|||||||||||||||||||||||||||||||||||||||||  1 [J] COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain
||||--||||||||--||||-|---|||||-|||||||----|-||||||||||||--||||||||  1 [G] COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family
|-||||-------|||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain
-------------||-||||||||||----||||||||||||||||||||||||||||||||||||  1 [R] COG0486 Predicted GTPase
--|-||||--|-|||||||--|--|-||||||--||||----|||||-||--|--|--||||||||  1 [ER] COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0495 Leucyl-tRNA synthetase
||||----|||-||--||||-||||-----------------|||||-||||||||||||||||--  1 [R] COG0496 Predicted acid phosphatase
----------------|-||||--|-||||||||||||----|||||-||||||||||||||||||  1 [L] COG0497 ATPase involved in DNA repair
|||||||||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1 [E] COG0498 Threonine synthase
|||||||||||||||-||||------||||-------------------|--|--|---|||||--  1 [H] COG0499 S-adenosylhomocysteine hydrolase
|||------|---||-|||||--|--|||||---|-||----||||||||||||||||||-|||--  1 [H] COG0502 Biotin synthase and related enzymes
||||--||-||||||--|||||--|||||-||||||||||||||||||||||-||||||||||---  1 [F] COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins
||||||||||||||||||||-|||||||||||||||||||--||||||||||||||||||||||||  1 [F] COG0504 CTP synthase (UTP-ammonia lyase)
||||||--||||-||-||||||----||||||||||||----||||||||-|||||||||||||--  1 [EF] COG0505 Carbamoylphosphate synthase small subunit
---|---------||---||-|----|||-----|-||----|||||--|-|-|||||||||||--  1 [E] COG0506 Proline dehydrogenase
---|||||---||||-||||-|||---|||--|-||||-|--|||||-||--||||---|||||--  1 [E] COG0509 Glycine cleavage system H protein (lipoate-binding)
||||||-||||||||-||||||----||||||||||||----||||||||||||||||||||||--  1 [EH] COG0512 Anthranilate/para-aminobenzoate synthases component II
--|---------||||--||||--|-|---||--||||----|||||-||||||||---||-||--  1 [L] COG0514 Superfamily II DNA helicase
|||||||||||||||-||||||-|-|||||||||||||----|||||-||||||||||||||||--  1 [F] COG0519 GMP synthase, PP-ATPase domain/subunit
|-||--||-|-||-|--||||||||||||||||||||||||||||||-|||||--|||||||||--  1 [E] COG0520 Selenocysteine lyase
|||||||||||||---|--|-|----|||||---||||----|||||-||||---|||||||||--  1 [H] COG0521 Molybdopterin biosynthesis enzymes
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0522 Ribosomal protein S4 and related proteins
|||||-|||||||||-||||-|||--||||||-|||||----||||||||||||||||||||||||  1 [E] COG0527 Aspartokinases
|||||||||||||---||||||||||||||||||||||||||||||||||||||||||||||||||  1 [F] COG0528 Uridylate kinase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0532 Translation initiation factor 2 (IF-2; GTPase)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0533 Metal-dependent proteases with possible chaperone activity
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [R] COG0536 Predicted GTPase
---|||--|-|||||-||||-|-----||--|--||||----|||||--|-|---|||-|||||--  1 [C] COG0538 Isocitrate dehydrogenases
-------------||-||||||||||||||||||||||-|--||||||||||||||||||||||||  1 [J] COG0539 Ribosomal protein S1
|||||||||||||||-||||||----||||||||||||----||||||||--||||||||||||--  1 [F] COG0540 Aspartate carbamoyltransferase, catalytic chain
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0541 Signal recognition particle GTPase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0550 Topoisomerase IA
|||||||||--------|--|-|||-----|||||||||-|||||||||||||||||||-------  1 [L] COG0551 Zn-finger domain associated with topoisomerase type I
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0552 Signal recognition particle GTPase
---|||-||--|||--||||||---|||||||||||||-||||||||-|||||--|---|||||--  1 [C] COG0554 Glycerol kinase
|-||------------|||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG0556 Helicase subunit of the DNA excision repair complex
|-|||||||-|||||||||||-|||||||||||||||||||||||||-||||||||||||||||||  1 [I] COG0558 Phosphatidylglycerophosphate synthase
|-||||||||||||||-||||||||||||||||||||||||||||||||-||-|||---||-|---  1 [R] COG0561 Predicted hydrolases of the HAD superfamily
--||--|||----|||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [F] COG0563 Adenylate kinase and related kinases
||||||--||-||-----||-|--------------------|||||-||||||||---|||||-|  1 [J] COG0565 rRNA methylase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0571 dsRNA-specific ribonuclease
||||---||||||---||||-|---||||||||||||||-|||||||-|-|||--|--||||||--  1 [P] COG0573 ABC-type phosphate transport system, permease component
|||||||||||||---||||||--|-|||||--|-||-----|||||-||--||||||||||||||  1 [G] COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase
|||||||||||||||||||||||||||||||||||||||||||||||-||||||||||||||||||  1 [I] COG0575 CDP-diglyceride synthetase
|-||||-------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0576 Molecular chaperone GrpE (heat shock protein)
||||----||||-----||||||||-|||-||||||||----|||||-||-|-|||--||||||--  1 [V] COG0577 ABC-type antimicrobial peptide transport system, permease component
---|||-----|-|||--|--|---|||||-|||||||----|||||-|||||--|---||||---  1 [C] COG0578 Glycerol-3-phosphate dehydrogenase
----|--||---|----||||-----|||-|---|--|-||||||-|-||--||||||||||||--  1 [R] COG0579 Predicted dehydrogenase
|-------|--|-|||-||-||---|----||||||||-|||||||||-||||--|---|||||--  1 [G] COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)
||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||--  1 [P] COG0581 ABC-type phosphate transport system, permease component
--|----------||-----|-||||||||||||||------||||||--||||||----||||--  1 [G] COG0588 Phosphoglycerate mutase 1
--|----------||||-||-|||--||||||-|||||----||||||||||||||---|||||||  1 [FJ] COG0590 Cytosine/adenosine deaminases
|-|||||||--||||---|-|--|--|------||-||----|||||-||||-||||||||||-||  1 [ER] COG0591 Na+/proline symporter
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)
-----------------||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0594 RNase P protein component
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [MU] COG0597 Lipoprotein signal peptidase
||||||||||||----|-|||---------||||||||----|||||-||||||||||||||||||  1 [O] COG0602 Organic radical activating enzymes
|||||||||||||---|-||----------|---|-||----|||||-||||||||||||||||||  1 [R] COG0603 Predicted PP-loop superfamily ATPase
|-||||----|||||||-||-|||-|||||||||||||----||||||||||||||||||||||||  1 [P] COG0605 Superoxide dismutase
|--------|------||||||---||||-|-----------|||||-||||||||||||||||-|  1 [O] COG0606 Predicted ATPase with chaperone activity
||||||||||||----|||||||||||---||||||||----|||||-||||||||||||||||||  1 [L] COG0608 Single-stranded DNA-specific exonuclease
-||||||||-|||----|||||----|---|||||||||---|||||-||||---|||||||||--  1 [P] COG0609 ABC-type Fe3+-siderophore transport system, permease component
|||||||||||||---|-||------||||------||----||||||||||||||--|----|--  1 [H] COG0611 Thiamine monophosphate kinase
||||----|--||---||||-|--------|------|----|||||-||||-|||----------  1 [R] COG0613 Predicted metal-dependent phosphoesterases (PHP family)
|||||||||||||||-||-----|--||||-|-|||||----||||||||||||||--||--||--  1 [E] COG0620 Methionine synthase II (cobalamin-independent)
----------------|-||-|||---|||-|--||||----|||-||-|||-|||||||||||||  1 [I] COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH)
-------------|----||------||||-|||||------|||||--|||-|||---|||||--  1 [R] COG0627 Predicted esterase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0629 Single-stranded DNA-binding protein
-----|-------||-|-||-|||--||||||||||||||||-------|--|--||--|--|---  1 [T] COG0631 Serine/threonine protein phosphatase
-----------------||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG0632 Holliday junction resolvasome, DNA-binding subunit
---|---------||||-||-|||--|---------------||||||||||-|||---|||||||  1 [C] COG0633 Ferredoxin
----------------||--||----||||||-|||||||||||||||||||||||---|||||--  1 [F] COG0634 Hypoxanthine-guanine phosphoribosyltransferase
||||||||||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [C] COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K
-|||||||||||||||-|||||--------||-|-|||----||||||||||||||--|||-||--  1 [T] COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases
-----------------|||||----|||||---||||----|||||-||-----|---|||||--  1 [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain
--|||||||-|||---||||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7
----------------|||||||||||||-|||||||||||||||||-||||||||||||||||-|  1 [R] COG0658 Predicted membrane metal-binding protein
|-||||-----|-||---||-------||||------|----|||||-||-|||||---|||||||  1 [R] COG0661 Predicted unusual protein kinase
|||---||||------|||||------||-------||----|||||-||--||||||-|||||--  1 [G] COG0662 Mannose-6-phosphate isomerase
|||-||||-|-|----|-||-|----|||-|-----||----|||-|-||--||||--||||||||  1 [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily
----------------||||||--||||||||||||||-|--||||||||||||||||||||||--  1 [H] COG0669 Phosphopantetheine adenylyltransferase
-------------||---||||||-|----|||||||--|--|||||-||||-|||||||||||||  1 [R] COG0670 Integral membrane protein, interacts with FtsH
||----||--|------|------------|---|-------|||||-||-||--|---||-|---  1 [M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase
-------------||---||-------------------------|--|-||-|||---|||||--  1 [O] COG0678 Peroxiredoxin
||-------|---||-|||||-----|---||--||||----||||--||-||--|--||||||||  1 [R] COG0679 Predicted permeases
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [M] COG0682 Prolipoprotein diacylglyceryltransferase
--|-||||--|||||-||||-|----|---||-|||||----||||||||||||||--||||||--  1 [E] COG0685 5,10-methylenetetrahydrofolate reductase
---|----|-|-|----|||||--||----||||||--|||||||||-||||-|||---|||||--  1 [E] COG0687 Spermidine/putrescine-binding periplasmic protein
||||----||---||-----||||---||||-----||----|||||-|||||||||||||||-||  1 [I] COG0688 Phosphatidylserine decarboxylase
|---|||||||||||||--|||----||||-----|||----|||||-||||||||---|||||||  1 [J] COG0689 RNase PH
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0690 Preprotein translocase subunit SecE
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0691 tmRNA-binding protein
-------------|||----||||-|||||-||||||||||||||||||||||||||||||-----  1 [L] COG0692 Uracil DNA glycosylase
|-||----|----|||-|||-|----|||||||||||-----|||||-||||||||---|||||||  1 [O] COG0695 Glutaredoxin and related proteins
-------------|||--||-|-----||-----|-||----|||----|-----||||-------  1 [R] COG0699 Predicted GTPases (dynamin-related)
------------------|-----------|-----||----|||-|-||-----|----------  1 [S] COG0700 Uncharacterized membrane protein
--|----------||-||||||||--||||||||||||----||||||||||||||||||||||--  1 [E] COG0703 Shikimate kinase
|||||||||||||---||||-|---|||||||||||-||-|||||||-||--|--|---|||||--  1 [P] COG0704 Phosphate uptake regulator
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0706 Preprotein translocase subunit YidC
--|------|-|----||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase
--|-------------|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0711 F0F1-type ATP synthase, subunit b
-------------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0712 F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)
--||||------|---|-||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)
|||||||||||||---|-||--||--|||||------|----||||||-|||||||||||||||||  1 [F] COG0717 Deoxycytidine deaminase
-----------------|||||||-|||||||||||||||||||||||||||||||||||||||||  1 [S] COG0718 Uncharacterized protein conserved in bacteria
||||||||||||----||||----------|---|-||----|||||-||||||||||||||||||  1 [H] COG0720 6-pyruvoyl-tetrahydropterin synthase
||||----||-||---||||||||||||||||||||||--||-------|---|||||||||||||  1 [J] COG0721 Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit
--||||----|||||-|-||-|----|||||-----||----------||--||||||||||||||  1 [C] COG0723 Rieske Fe-S protein
|||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||--  1 [P] COG0725 ABC-type molybdate transport system, periplasmic component
-|||--|||-||------||-|---------||---------|||||-||--|--||||-|-|---  1 [R] COG0727 Predicted Fe-S-cluster oxidoreductase
----------------|||||||||||||||-----------||||||||||||||||||||||||  1 [R] COG0728 Uncharacterized membrane protein, putative virulence factor
----------------|---|---------------------|||||-||||||||---|||||--  1 [M] COG0729 Outer membrane protein
-------------||-||--|||||||||||||||||||||||||||||----|||||||||||||  1 [I] COG0736 Phosphopantetheinyl transferase (holo-ACP synthase)
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1 [OU] COG0740 Protease subunit of ATP-dependent Clp proteases
-----------------|||||||||||||||||||||-|--||||||||||||||||||||||||  1 [L] COG0742 N6-adenine-specific methylase
----------------|||||||||-|||||----|||----|||||||||||||||||||--|--  1 [I] COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase
|||||||||||||---|-||-|----|||-----||||----|||||-||||--||||||||||--  1 [H] COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A
-------------|--||||||||||||||||||||||----|||||-||||||||||||||||||  1 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains
|||||||||||||---||||||||||||||||||||||----|||||-||||||||||||||||||  1 [M] COG0750 Predicted membrane-associated Zn-dependent proteases 1
----------------|||||-||-------|||-|||----||||||||||||||||||||||||  1 [J] COG0751 Glycyl-tRNA synthetase, beta subunit
----------------|||||-||-------|||-|||----||||||||||||||||||||||||  1 [J] COG0752 Glycyl-tRNA synthetase, alpha subunit
-------------||------|----|-------||||----|||||-||||-||||||||||---  1 [P] COG0753 Catalase
--|-----|-|-|---|-||-|----||||----|-||----|||||-||||||||||||||||||  1 [O] COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component
-------------||||---|-|||-||||||||-||-----||||||-|||||||||-|||||||  1 [F] COG0756 dUTPase
----------------||||||--|||||-|-||||||||--|||||-||||||||||||||||-|  1 [LU] COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake
----------------||||||||||-||-||||||||----|---|-|||||||||||||||||-  1 [S] COG0759 Uncharacterized conserved protein
----------------|||||||||-|||||-----||----||||||||||||||||||||||--  1 [IM] COG0761 Penicillin tolerance protein
-----------------||||-||||||||||||||||----|||||-||||---||||||-||--  1 [S] COG0762 Predicted integral membrane protein
----------------|-|||-||------------------|||||-||||||||||||||||||  1 [M] COG0763 Lipid A disaccharide synthetase
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase
|--------|------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0769 UDP-N-acetylmuramyl tripeptide synthase
|||------|------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase
|--------|------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase
----------------|-|||-||------------------|||||-||||||||||||||||||  1 [M] COG0774 UDP-3-O-acyl-N-acetylglucosamine deacetylase
----------------|-||||||--|||-||||||||----|||||-||||||||||||||||--  1 [I] COG0777 Acetyl-CoA carboxylase beta subunit
----------------||||||--|||||-||||||||----|||||-||||||||||||||||||  1 [S] COG0779 Uncharacterized protein conserved in bacteria
----------|-|---||||-------------||-||----|||||-||||||||||||||||||  1 [R] COG0780 Enzyme related to GTP cyclohydrolase I
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0781 Transcription termination factor
---|--------------||||--|||----|||||||-|--|||||-|||||--|||||-|-|||  1 [P] COG0783 DNA-binding ferritin-like protein (oxidative damage protectant)
--------------|-|-||||--||||||||||||||----|||||-||||||||||||||||||  1 [M] COG0787 Alanine racemase
----------------||||||--|-|||||-----------|||||-||||||||||||||||--  1 [L] COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase
----||----||----||||||||||----|---||||----|||||-||||||||||||||||||  1 [M] COG0793 Periplasmic protease
|||---|||||||---|---|-||------|---|||-----|||||-||||||||||||||||||  1 [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation
----------------|-||||--||||||||||||||----||||||||||-|||||||||||--  1 [M] COG0796 Glutamate racemase
----------------|-||----||----|-----------|||||-||||||||||||||||||  1 [M] COG0797 Lipoproteins
----------------||||-|||||||||-|||||||----|||||-||||||||||||||||||  1 [S] COG0799 Uncharacterized homolog of plant Iojap protein
-------------||-||||||||--||||||||||||----|||||-||||||||||||||||-|  1 [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase
----------------||||||||||||||||||||||-|--|||||-||||||||||||||||||  1 [R] COG0802 Predicted ATPase or kinase
--------------|---||-|----|||-----|-|||----|||---||----|||-||||---  1 [E] COG0804 Urea amidohydrolase (urease) alpha subunit
--||||--|-|||---|-||-|----||||----||||----|||||-||||||||||||||||||  1 [U] COG0805 Sec-independent protein secretion pathway component TatC
----------------||||||--||||||||||||||----||||||||||||||||||||||||  1 [J] COG0806 RimM protein, required for 16S rRNA processing
----||--|----||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG0807 GTP cyclohydrolase II
----------------||||||---|----||||||||----||||||||||||||||||||||||  1 [J] COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0812 UDP-N-acetylmuramate dehydrogenase
----------------||||-|||||||||------------|||||-||||-|||||||||||||  1 [M] COG0815 Apolipoprotein N-acyltransferase
----------------||||||||--|||||||-||||||||||||||||||||||||||||||||  1 [L] COG0816 Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis)
-----------------||||||||-||||------------|||||-||||||||||||||||||  1 [L] COG0817 Holliday junction resolvasome, endonuclease subunit
-----------------|||-|--------||||||||----|||||-|||||||||||||||---  1 [M] COG0818 Diacylglycerol kinase
----------------||||||--|-|||-|||||||||---||||||||||||||||||||||--  1 [R] COG0820 Predicted Fe-S-cluster redox enzyme
----------------|||||||||-|||||-----||----||||||||||||||||||||||--  1 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis
--||----|----|||||-||-||||||||||||||||||||||||||||||-|||||||||||||  1 [C] COG0822 NifU homolog involved in Fe-S cluster formation
----------------|-||||||--|||-||||||||----|||||-||||||||||||||||--  1 [I] COG0825 Acetyl-CoA carboxylase alpha subunit
----------------|-||--||||----|||||||||-||||||||||||||||||||||||||  1 [J] COG0828 Ribosomal protein S21
--------------|---||-|----|-------|--||----||----||----|||-||||---  1 [O] COG0829 Urease accessory protein UreH
--------------|---||-|----|||-----|--||----|||---||----|||-||||---  1 [O] COG0830 Urease accessory protein UreF
--------------|---||-|----|||-----|-|||----|||---||----|||-||||---  1 [E] COG0831 Urea amidohydrolase (urease) gamma subunit
--------------|---||-|----|||-----|-|||----|||---||----|||--|||---  1 [E] COG0832 Urea amidohydrolase (urease) beta subunit
------------------||----------------------|||||--|--||||||-|||||--  1 [G] COG0837 Glucokinase
--||||--|-|||---|-||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A)
--||||--|--||---|-||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J)
------||||||||||||--||----|||||-|-||||-|--|||||-||-|---||||----|--  1 [K] COG0846 NAD-dependent protein deacetylases, SIR2 family
----|---|----||||||--||||-|||-||||||||----||||||||||||||||||||||||  1 [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
---------|------||--||--||----||||||||----||||||||||||||||||||||||  1 [D] COG0849 Actin-like ATPase involved in cell division
----------------||||||--------|----|||----||||||||-|||||||-||||---  1 [D] COG0850 Septum formation inhibitor
------------------||||--------------------||||||||--||||||-||||---  1 [D] COG0851 Septum formation topological specificity factor
--|||||||-|||---||||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit
----------------||||-|----|||||---||||----|||||--|--||||||||--||--  1 [H] COG0853 Aspartate 1-decarboxylase
----------------|-||----------------------|||||-||--||||||||||||--  1 [H] COG0854 Pyridoxal phosphate biosynthesis protein
--|---------------||-|-----||||------|----|||||-||--||||||||||||--  1 [P] COG0855 Polyphosphate kinase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0858 Ribosome-binding factor A
----------------|-|||||||||||||---||||----||||||||||||||||||||||--  1 [M] COG0860 N-acetylmuramoyl-L-alanine amidase
---|||||---||||-||||-|-----|||----||||----|||||--|--|-||---|||||--  1 [E] COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain
-|||---||--|----|-||------|||---|---||----|||||-||-||--|--||||||||  1 [M] COG1004 Predicted UDP-glucose 6-dehydrogenase
--||||--|-|||---|-||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H)
--||||--|-|||---|-||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N)
--||||----------|-||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M)
--||||-||-|||---|-||-|----|||-----||||----||||||||--||||||||||||||  1 [CP] COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit
||||||--||||------|||------||-|----|----------|--|-----|---||||---  1 [H] COG1010 Precorrin-3B methylase
-------------||-|----|----|-------|-||----|||||-||--|--|--|-|-----  1 [C] COG1017 Hemoglobin-like flavoprotein
--|-|||||-|-|---|-----------------|-||-----------|-----|----|-|---  1 [O] COG1030 Membrane-bound serine protease (ClpP class)
----------------||||-|-----||-|-----------||||||-|--||||||||||||||  1 [C] COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)
----------------||||||--||-||-||||||||----|||||-||||||||||||||||-|  1 [R] COG1040 Predicted amidophosphoribosyltransferases
----------------|-|||-||------------------|||||-||||||||||||||||||  1 [M] COG1043 Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase
----------------|-|||-||------------------|||||-||||||||||||||||||  1 [M] COG1044 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase
------------------||----------------------|||||-||-|||||||||------  1 [C] COG1049 Aconitase B
||-|||--|||||||-||||||||--||||||--||||----|||||-||||||||||||||||||  1 [C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit
------------------||-|||--|----||||||-----||||||||--|--|---|||||||  1 [R] COG1054 Predicted sulfurtransferase
----|||||-|||----||||-||---|||----||||----||||--||---|||--||--|---  1 [P] COG1055 Na+/H+ antiporter NhaD and related arsenite permeases
|||||||||-|||-----|--|-----||--|----------|||||---||---|----------  1 [H] COG1056 Nicotinamide mononucleotide adenylyltransferase
-------------||-|||||---||||||||||||||||||||||||||--||||||||||||--  1 [H] COG1057 Nicotinic acid mononucleotide adenylyltransferase
---||||||-||||---|||||-----||||-||||||----|||||-|----|||---|||||--  1 [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA
----------------|||||||||-|||-|||-||||----|||||-||||||||||||||||||  1 [O] COG1066 Predicted ATP-dependent serine protease
--------|---|||--|||----|||||-||-|||||----|||||--|||---|---||||---  1 [G] COG1070 Sugar (pentulose and hexulose) kinases
---|||----||||||--||-|||---||--|||||||-|||-------|-----|---|||||||  1 [C] COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
--------------------|-||||-||-||||||||----||||||||||||||||||||||||  1 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)
--------|----||---||-|----|---|---|-||-|--------||--|--|----------  1 [R] COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold
-------------|||--|-----------------------||||||||||-|||--||||||||  1 [O] COG1076 DnaJ-domain-containing proteins 1
|---||--||------||-||-||||----|----|||----|||||-|||||--||||----|||  1 [D] COG1077 Actin-like ATPase involved in cell morphogenesis
---|--|||-|-|----|-|-|--||----||||-||-||||-------|-----|---||||---  1 [R] COG1079 Uncharacterized ABC-type transport system, permease component
-|---------------|--|---|-|---|--||-||----------||-||||||||-||||||  1 [MG] COG1086 Predicted nucleoside-diphosphate sugar epimerases
|------------||-|-||||----|---||-|-|||--|||||||-||||-|||||||||||--  1 [M] COG1087 UDP-glucose 4-epimerase
|-|--||||--||-|---||||----|||||||---||----|||||--|||||||---||-||--  1 [M] COG1088 dTDP-D-glucose 4,6-dehydratase
-|----||-|--|---||--||||-------||||||-----||||||||||||||---||||---  1 [R] COG1092 Predicted SAM-dependent methyltransferases
--------------------|-----|-----||--------------||-----|---||||-||  1 [R] COG1101 ABC-type uncharacterized transport system, ATPase component
-----------------|--||---||||-||||||||--|||||||-||||---|----------  1 [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)
||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||--  1 [P] COG1117 ABC-type phosphate transport system, ATPase component
-||||||||--||----|||||----|---|-|||||||-|||||||-||||---|||||||||--  1 [PH] COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components
||||--|||||||----|||||--|-||||||||||||||||-||-|-|-|----|---|||----  1 [P] COG1122 ABC-type cobalt transport system, ATPase component
|||-|----|-|------|||-----||||----|-------|||||-|------|||-||-|---  1 [R] COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase
------------------||||-||-|---||||||||----|||||-||||||||||||||||--  1 [P] COG1135 ABC-type metal ion transport system, ATPase component
----------------||||||||||----------------|||||-||||||||||||||||||  1 [R] COG1137 ABC-type (unclassified) transport system, ATPase component
|--|||--|-|||-------||---------|----||----|||------|-||||||-------  1 [C] COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain
----------|-|-------------|||-----|-|-----|||-|--|-----|-----|----  1 [C] COG1140 Nitrate reductase beta subunit
|||||||||-|||---||||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)
----------------|||||||||-||||||---|||----||||||||||||||||||||||--  1 [HI] COG1154 Deoxyxylulose-5-phosphate synthase
----------------||--|||||||||||---||||----||||||||||||||||||||||||  1 [K] COG1158 Transcription termination factor
----------------||||||--||||||||||||||||||||||||||||||||||||||||||  1 [R] COG1159 GTPase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [R] COG1160 Predicted GTPases
--|-------------|||||----||||||||||||||||||||||-||||||||------|---  1 [R] COG1162 Predicted GTPases
--------------------||----||||||-|-|||----|||||---|----|----------  1 [E] COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
--------|----------|||-----||-|||||||-----|||||--|-----|||-||||---  1 [E] COG1174 ABC-type proline/glycine betaine transport systems, permease component
---|----|-|-|----|-|||--||----||||||--|||||||||-||||-|||---|||||--  1 [E] COG1176 ABC-type spermidine/putrescine transport system, permease component I
---|--||--|-|-----||||--|-|------|---|----|||||-||||-|||--|||||---  1 [P] COG1178 ABC-type Fe3+ transport system, permease component
-------------||-----|---------|---|-||----|||||-|||||||||||-------  1 [H] COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
|||-|||||||||---||--|------||-||||||------|||||-||||---|----------  1 [O] COG1180 Pyruvate-formate lyase-activating enzyme
--|-------------||||||||||||||||||||||----|||||-||||||||||||||||||  1 [M] COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes
-------------------|----------||--||||-||||||||--||----|---||-|---  1 [I] COG1182 Acyl carrier protein phosphodiesterase
||||----||---||-----|-||-|-||||-----||-----------|--|||||||||||-||  1 [I] COG1183 Phosphatidylserine synthase
-------------||-||||||||||||||||||||||----||||||||||||||||||||||||  1 [J] COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)
-----------------|--|-----|---||||||||----|||||-||||-|||||||||||--  1 [J] COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
--|-------||-|||||||||||--|||||||||||||||||||||||||||||||||||-----  1 [J] COG1190 Lysyl-tRNA synthetase (class II)
----------------||||--|||--||-|---||||----|||||-||-----||||-------  1 [K] COG1191 DNA-directed RNA polymerase specialized sigma subunit
|--|------|-|-|------||||-||||||||||||----||||||||||||||||||||||--  1 [L] COG1194 A/G-specific DNA glycosylase
-----------------|||||||||||||||||||||----||||||||||||||||||||||||  1 [LK] COG1197 Transcription-repair coupling factor (superfamily II helicase)
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1 [L] COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase
||||||||--|||||||-|||-----|||-||||||||----|||||-||||||||-------|--  1 [KL] COG1199 Rad3-related DNA helicases
----------------||||||--||||||||||||||----|||||-||||||||||||||||||  1 [LK] COG1200 RecG-like helicase
|||||||||||||------|------|||-------------|||----|-----|---|||||--  1 [R] COG1201 Lhr-like helicases
----------------||||||----||||||||||||----||||||||||||||||||||||||  1 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)
|||||||||||||||||-||-|----|||||-----||-------||--|--||||--||||||--  1 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)
|-|||||||--||----|||-|----|||||||---||----|||||--|--||||---||-||--  1 [M] COG1209 dTDP-glucose pyrophosphorylase
------|---------|||||||||-|||||--|||||--||||||||||||||||||||||||--  1 [I] COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase
----------------|---|-||------------------|||||-||||||||||||||||||  1 [M] COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone
|-|-||||||||-||||-||------|---|||-||||----|||||--|-----|---|||||-|  1 [M] COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
------------------||||----||||||||||||----||||||||||||||||||||||||  1 [T] COG1217 Predicted membrane GTPase involved in stress response
-------------|--||||||||||||||||||||||----||||||||||||||||||||||||  1 [O] COG1219 ATP-dependent protease Clp, ATPase subunit
----------------||-------|--------||||----|||||||||||--|||||||||||  1 [O] COG1220 ATP-dependent protease HslVU (ClpYQ), ATPase subunit
--||||----|||||-||||-|----|||||---|-||----|||||-||||||||||||||||-|  1 [O] COG1225 Peroxiredoxin
|--||||-|--|-|---|--||-----||-|-|-|-||-------||-||-----|---|||||--  1 [Q] COG1228 Imidazolonepropionase and related amidohydrolases
------------------||-|----|||-------|------------|-----|------||--  1 [E] COG1231 Monoamine oxidase
--||--|-|-|--||-|----|||--||||----||||-------|---------|-------|--  1 [H] COG1232 Protoporphyrinogen oxidase
||||-------||-----||-|----|||-----||-|-----------------|------||--  1 [Q] COG1233 Phytoene dehydrogenase and related proteins
||||||||||----|-|-|||-||||----||||||||----||||---|-----|---|||||||  1 [R] COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
-||||||-|-||||||--||-|--------------------------||-----|---||-||--  1 [J] COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing
-||------|------|-------------------------|||||-||||||||--||||||||  1 [S] COG1238 Predicted membrane protein
||||||--||--------||-|----|||--------------------|-----|----------  1 [H] COG1239 Mg-chelatase subunit ChlI
||||||---|--------||------|||--------------------|-----|----------  1 [H] COG1240 Mg-chelatase subunit ChlD
---|-------|-||---||-|----||||-|--||||----|||||-|||----|---||||---  1 [C] COG1252 NADH dehydrogenase, FAD-containing subunit
----------------||------||----|----|||----||||||||-----|||||||||--  1 [N] COG1256 Flagellar hook-associated protein
----------------||------------------------||||||||-----|||||||||--  1 [NO] COG1261 Flagellar basal body P-ring biosynthesis protein
--------------------|----||---||||||||-|||||||||||-|---|-------|--  1 [G] COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific
--------------------|----||---||||||||||||||||||||-|---|-------|--  1 [G] COG1264 Phosphotransferase system IIB components
|-||--||--|-|---|||||||||||||-||||||||-----||||-||-----|------||--  1 [R] COG1266 Predicted metal-dependent membrane protease
|||---||-||-|---|---|-----------|--|||----|||||-||||-||||||-----||  1 [I] COG1267 Phosphatidylglycerophosphatase A and related proteins
----||||---|----------|||-||||-------------------------|----------  1 [C] COG1274 Phosphoenolpyruvate carboxykinase (GTP)
----------------|----|-------------|||----|||||--------|----|-|---  1 [P] COG1276 Putative copper export protein
--|||||||--||----|||-|--||----|---|||||||--------|-----|----||----  1 [R] COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
----------------||||||--------||||||||-|--|||||-||||||||---|||||--  1 [O] COG1281 Disulfide bond chaperones of the HSP33 family
----------------|-||||--|--||-||-|-|||----|||||--|||---|---|||----  1 [S] COG1285 Uncharacterized membrane protein
------------------------||-----|||||||----|||||-||||||||||||||||||  1 [R] COG1286 Uncharacterized membrane protein, required for colicin V production
---|||----||||--|-||-|----||||------||----------||--||||||||||||||  1 [C] COG1290 Cytochrome b subunit of the bc complex
----------------||------||----|----|||----|||||-||-----|||||||||--  1 [N] COG1291 Flagellar motor component
---|--|------|-------------||--------------------||-||||--|----|--  1 [S] COG1297 Predicted membrane protein
----------------||----||||----|----|||----||||||||-----|||||||||--  1 [NU] COG1298 Flagellar biosynthesis pathway, component FlhA
--------------------||---||---||||||||-||||||||-|||----|----------  1 [G] COG1299 Phosphotransferase system, fructose-specific IIC component
|-|||||||||||||||-||-|-----||--------------||||--|-----|----------  1 [R] COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily
----------------|-|||||||||||||||||||||-|-||||||||||||||||||||||||  1 [U] COG1314 Preprotein translocase subunit SecG
----------|||--------|--||-||-------||----|||----|-----|---||-|---  1 [C] COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs
----------------------||-------|||-----|--|||||-||||||||---|||||||  1 [S] COG1322 Uncharacterized protein conserved in bacteria
|-|-|||||||-|--|||-|-|-|------------------|||||-----|--|--------||  1 [P] COG1324 Uncharacterized protein involved in tolerance to divalent cations
-----------------||-||||--||||||||||||----|||||-||||||||---|||||--  1 [K] COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains
|||---||-|-------|--|---------||||||------|||||-||||---|----------  1 [F] COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase
----------------|-||------||||------||---------------|||----------  1 [O] COG1333 ResB protein required for cytochrome c biosynthesis
----------------||----||||----|----|||----||||||||-----|||||||||--  1 [NU] COG1338 Flagellar biosynthesis pathway, component FliP
----------------||------||----|----|||----|||||-||-----||||-------  1 [N] COG1345 Flagellar capping protein
--|---||------------||--------||--|-||----|||||-||||-|||-----|----  1 [M] COG1346 Putative effector of murein hydrolase
----------------||--||----|---||||||||----|||||-||||-|||---||||---  1 [KG] COG1349 Transcriptional regulators of sugar metabolism
-||||||||-------||||||--|-||||||||||||||||-------|--||||---|||||--  1 [S] COG1354 Uncharacterized conserved protein
--||--------------|-||----|||-||-|-||-----|||||-||-|-|||---||-||--  1 [S] COG1359 Uncharacterized conserved protein
|||-----||---||-||||-|----||||||--||||-----------|---|||---|||||--  1 [E] COG1364 N-acetylglutamate synthase (N-acetylornithine aminotransferase)
-----------------|||------|||||-----||----|||-|-||---|||---||||---  1 [S] COG1376 Uncharacterized protein conserved in bacteria
--|---||------------||--------||--|-||----|||||-||||-|||-----|----  1 [R] COG1380 Putative effector of murein hydrolase LrgA
------------------|||||||-||||||||||||||--|||||-||||||||---|||||||  1 [L] COG1381 Recombinational DNA repair protein (RecF pathway)
----------------||||||--||||||||||||||||--||||||||||||||||||||||||  1 [S] COG1385 Uncharacterized protein conserved in bacteria
--|-|||||--------|||||--|-||||||||||||||||-------|--||||---|||||--  1 [K] COG1386 Predicted transcriptional regulator containing the HTH domain
----------------|---------||||------------|||||-||||-|||---|||||--  1 [OT] COG1391 Glutamine synthetase adenylyltransferase
|||---|||--|-----|---|||------|---|||-----------||||---|---||-|---  1 [P] COG1392 Phosphate transport regulator (distant homolog of PhoU)
----------------||||-|----||||||||||||----|||||-||||||||----------  1 [R] COG1399 Predicted metal-binding, possibly nucleic acid-binding protein
|-|-------|-----|--|-|||--||||||---|||----|------------||||-|-|---  1 [R] COG1408 Predicted phosphohydrolases
-----------------|||-|----|||||------|----|||||-|||-|--|---|||||--  1 [E] COG1410 Methionine synthase I, cobalamin-binding domain
|--|||--|-------|----|---------------------------------|------|---  1 [S] COG1416 Uncharacterized conserved protein
----------------||------||----|----|||----------||-----||||-------  1 [N] COG1419 Flagellar GTP-binding protein
-----------------||||-||--||||||||||||||||----------|--|||||||||--  1 [K] COG1420 Transcriptional regulator of heat shock gene
-----------------|-|--||||-----|||||||----|||||-|||||--|--------||  1 [S] COG1426 Uncharacterized protein conserved in bacteria
---------------------|---|-----||-|||-||||-------------|----------  1 [F] COG1428 Deoxynucleoside kinases
||||-----|--------||-------||--------------------|-----|---||||---  1 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases
||-|--||-||------|||----||--------------------------|--|---|||||--  1 [S] COG1430 Uncharacterized conserved protein
||||--|||||||------------|----|--------------|---------|----------  1 [F] COG1437 Adenylate cyclase, class 2 (thermophilic)
--------------------||---||---||||||||-||||||||-||||---|----------  1 [G] COG1445 Phosphotransferase system fructose-specific component IIB
---|||||--||--|---||----------------------|||-|-|------|---|---|--  1 [E] COG1446 Asparaginase
-------------||-----|-||------------------|||||-||||||||----|-|---  1 [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase
||||--|||-------|---||----|---|-------||--|||||-||--||||||||||||-|  1 [R] COG1451 Predicted metal-dependent hydrolase
----------------|-------||----------------|||||-||||||||||||||||||  1 [M] COG1452 Organic solvent tolerance protein OstA
----------------|-||-|--------------------|||||--|---|||-------|--  1 [M] COG1462 Uncharacterized protein involved in formation of curli polymers
----------------||||-|||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG1466 DNA polymerase III, delta subunit
||||||||||--|----|----------------|-||-----------|--||||----------  1 [S] COG1469 Uncharacterized conserved protein
-------------||------|-----||-------------|||||-||--||||---|||||||  1 [R] COG1485 Predicted ATPase
-||---|||-||------||-|-----||-----------------|---|-|--|---||-||-|  1 [R] COG1487 Predicted nucleic acid-binding protein, contains PIN domain
-------------||-||--||----|||-||||||||----|||||-||||-|||----------  1 [J] COG1490 D-Tyr-tRNAtyr deacylase
||||||--||-|------||||-----||-|----|-|--------|-||-----|---|||||--  1 [H] COG1492 Cobyric acid synthase
---------|----------|---|-----||||||||||||----------||||---|||||--  1 [T] COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism
----------------|-||||||-||||||---|-||----|||||-||||||||--||||||||  1 [S] COG1496 Uncharacterized conserved protein
----||----||-||--|-|----------||-|-|-|----|||||--------|---|---|--  1 [G] COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases
-|----||--------------------------|-|------------------|---|-|----  1 [K] COG1510 Predicted transcriptional regulators
-----------------|||----|------|----||----|||----|-|---|-----|||--  1 [R] COG1512 Beta-propeller domains of methanol dehydrogenase type
----------------|-||----------------------|||----|-----|----------  1 [P] COG1513 Cyanate lyase
----------------||------||----|----|||----|||||-||-----||||-------  1 [NUO] COG1516 Flagellin-specific chaperone FliS
----------------|---|-||------------------|||||-||||||||||||||||||  1 [M] COG1519 3-deoxy-D-manno-octulosonic-acid transferase
||||--|||--------|---|---|-|||------|-----|||||-||--|--|-------|||  1 [S] COG1520 FOG: WD40-like repeat
----------------||||||--||-||||----|||-|---------|--|||||||----|--  1 [K] COG1521 Putative transcriptional regulator, homolog of Bvg accessory factor
--|--------|-----||-||||--|||-|-||--||-|--|||||-||||---|---||-|---  1 [G] COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases
-||-|-|||||||----||-|------||-|-----||-----------|-----|---|||||-|  1 [L] COG1533 DNA repair photolyase
||||--||||-||-------|---------||||||||----|||||-||||||||----------  1 [J] COG1534 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein
----------------||----||||----|----|||----||||||||-----|||||||||--  1 [N] COG1536 Flagellar motor switch protein
|-|-----|--|-------|||---------------|----|--|--|---|--|----------  1 [H] COG1541 Coenzyme F390 synthetase
----------------||||||-|-|||||||||||||----|||||-|||||--|---|||||||  1 [J] COG1544 Ribosome-associated protein Y (PSrp-1)
---|------------||||||----|||||-||-||||||||||||-||--||||||||||||--  1 [R] COG1546 Uncharacterized protein (competence- and mitomycin-induced)
--|--------------|||||----|||-||||||||----|||||-||||||||--|-------  1 [L] COG1555 DNA uptake protein and related DNA-binding proteins
---|----|-----------||---------|----||----|||------|-||||||-------  1 [S] COG1556 Uncharacterized conserved protein
----------------||------||----|----|||----||||||||-----|||||||||--  1 [N] COG1558 Flagellar basal body rod protein
----------------|---||--||||||||||-|||----|||||-||||||||||||||||||  1 [R] COG1559 Predicted periplasmic solute-binding protein
----------------||--|----|----|----|||----|||||-||||||||---|||||--  1 [S] COG1561 Uncharacterized stress-induced protein
|--|-------|-||---||-|----|||-----|-|---------------||||---|||||--  1 [I] COG1562 Phytoene/squalene synthetase
----------------|-||--------------------------------||||||||||||||  1 [S] COG1565 Uncharacterized conserved protein
-----------------|-|||||--||||||||||||----|||||-||||||||||||||||||  1 [L] COG1570 Exonuclease VII, large subunit
-----------------|--||--------||||||||||--|||||-||||||||||||||||--  1 [S] COG1576 Uncharacterized conserved protein
----------------||------||----|-----||----|||||-||-----||||-------  1 [N] COG1580 Flagellar basal body-associated protein
-|--|||||-|||---||------------|-----||----||||||-|--|--|----------  1 [E] COG1586 S-adenosylmethionine decarboxylase
||||||--||||-||-|-||||||--|||||---||||----|||||-||-||||||||||||---  1 [H] COG1587 Uroporphyrinogen-III synthase
------------------||-|--||||||||||||||----|||||-||||||||---|||||||  1 [M] COG1589 Cell division septal protein
----------------||||----------------------|||-|-||-|||||--||||||--  1 [M] COG1596 Periplasmic protein involved in polysaccharide export
|-|-----|---------||-|--------|-|-||||----|||||-||-----|---|||||--  1 [C] COG1600 Uncharacterized Fe-S protein
-------------|---|--------|||-|----|||----------||--||||--|||||---  1 [S] COG1610 Uncharacterized conserved protein
---|--------|||-|-||-|----||||----||||-----------|--|--|---|||||||  1 [O] COG1612 Uncharacterized protein required for cytochrome oxidase assembly
------------------||-------|||-------|----|||||--|--||||---|||||--  1 [P] COG1613 ABC-type sulfate transport system, periplasmic component
----||------------||||--|-----||-|-|||-|--|||-|-||---|||--------||  1 [V] COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF
---|----||-|---------|---|--------|-||----|||-|-||||-||||||--|----  1 [C] COG1620 L-lactate permease
-------------||--|--------|---|-|||-||-----||---|--|---|---|------  1 [G] COG1621 Beta-fructosidases (levanase/invertase)
-------------|||---|----||----------------|||-|--|-----|----------  1 [G] COG1626 Neutral trehalase
----------|-----|-||||||-||||--|||--------|||||-||||---|----------  1 [G] COG1640 4-alpha-glucanotransferase
-------------|||-----|--|||---------------|||||-||||||||---|||||--  1 [L] COG1643 HrpA-like helicases
------------------||-|--------------|-----||||---------|-----|----  1 [S] COG1649 Uncharacterized protein conserved in bacteria
---|----|-|-----|-||-|||--||||----|||-----|||||-||||||||||||||||||  1 [O] COG1651 Protein-disulfide isomerase
----|||||||||---||------|--||--------------------------|----------  1 [S] COG1656 Uncharacterized conserved protein
--------------------||----||||||||||||----|||||-||||||||----------  1 [R] COG1660 Predicted P-loop-containing kinase
----------------|---|-||------------------|||||-||||||||||||||||||  1 [M] COG1663 Tetraacyldisaccharide-1-P 4'-kinase
----------------------||||----|-----|--------|--||--|--||||----|--  1 [M] COG1664 Integral membrane protein CcmA involved in cell shape determination
-------------------|-------||-------||----|||||-||||---|--|-------  1 [S] COG1666 Uncharacterized protein conserved in bacteria
-|||||-|-----||--|-|||----||||||||||||--|-|||||-||-|-|||||||||||||  1 [J] COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
----------------||------||----|----|||----||||||||-----|||||||||--  1 [NU] COG1677 Flagellar hook-basal body protein
---------------------|||--||||------------|||||-||||||||---|||||||  1 [K] COG1678 Putative transcriptional regulator
|-|-------------||--|---------|----|||--------|-||-----|---||-|---  1 [S] COG1683 Uncharacterized conserved protein
----------------||------||----|----|||----||||||||-----|||||||||--  1 [NU] COG1684 Flagellar biosynthesis pathway, component FliR
---------||-|---||||-|----||||-|||||||----|||||-||-|||||---|||||--  1 [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase
---||||||--||--------|----||||-------|----|||----------|-------|--  1 [E] COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family
-||--------------|--|---|-------||-|--||---|||---|-|---|---|||||--  1 [S] COG1704 Uncharacterized conserved protein
-----------------|-------------||-|||-----|||||-||-----|-----|----  1 [NU] COG1705 Muramidase (flagellum-specific)
----------------||-------|----------------||||||||-----|||||||||--  1 [N] COG1706 Flagellar basal-body P-ring protein
|||-----|||------|-------------------------------|-----|----------  1 [R] COG1712 Predicted dinucleotide-utilizing enzyme
|--------|--------||-------||||----|||----------|||--|||||||||||||  1 [S] COG1714 Predicted membrane protein/domain
--|||||||-|-|---||||-|---|-|||-----|||----------||-----|---|||||--  1 [R] COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
-----------------|-|||----||||||||||||----|||||-||||||||||||||||||  1 [L] COG1722 Exonuclease VII small subunit
----------------|-------------------------|||||-||--||||---|||||||  1 [S] COG1729 Uncharacterized protein conserved in bacteria
---|----|----------|||-----||-|||||||-----|||-|--|-----|||-||||---  1 [M] COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
--||---------||--|--||---||---||||||||||--|||-|-||||-|||||||||----  1 [S] COG1739 Uncharacterized conserved protein
--|---------------|--------||-----|-||----|||-|--|-----|---||-||--  1 [S] COG1742 Uncharacterized conserved protein
---|--|||-|-|----|-|-|--||----||||-|||||||-------|-----|---||||---  1 [R] COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein
----------------|-------||----|----|------||||||||-----|||||||||--  1 [N] COG1749 Flagellar hook protein FlgE
||||||||||||||||||||-|--||||||||||||||----|||||-||||||||||||||||||  1 [K] COG1758 DNA-directed RNA polymerase, subunit K/omega
--------------------|-|||||---||||||||-||||||||-||||-|||---|||||--  1 [GT] COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)
----------------||------||----|----|||----||||||||-----|||||||||--  1 [NU] COG1766 Flagellar biosynthesis/type III secretory pathway lipoprotein
||-----||--------||||---|--||-|-----------|||-|--|--||||-------|--  1 [C] COG1773 Rubredoxin
--|-------------|---|---------------------|||||-|||||||||||-------  1 [R] COG1778 Low specificity phosphatase (HAD superfamily)
----------------|--||-||||----||-|||||----|||||-|||||--||||----|||  1 [M] COG1792 Cell shape-determining protein
------|||----------------------|----|-----|||||----|---|--|||-||--  1 [M] COG1794 Aspartate racemase
||||||--||||------||||-----||-|----|-|--------|--|-----|---||||---  1 [H] COG1797 Cobyrinic acid a,c-diamide synthase
--|-|||||-|||---||-|-|------------||||----|||||-||-|---|---||-||--  1 [S] COG1801 Uncharacterized conserved protein
-----------------||------|----|----|||----|||||-|-||---|---|||----  1 [G] COG1803 Methylglyoxal synthase
---------------------|------------||||----|||||-||--||||---|||||||  1 [S] COG1806 Uncharacterized protein conserved in bacteria
----------------||------||----|----|||----||||||||-----|||||||||--  1 [N] COG1815 Flagellar basal body protein
-------------||----|----|--|-|||----------|||-|-||-----|---||-||--  1 [F] COG1816 Adenosine deaminase
----------------||||-|||||||||----||||----||||||||||||||||||||||||  1 [J] COG1825 Ribosomal protein L25 (general stress protein Ctc)
---|||||--|||---||---|---------|||-|||----|||||--------|--|||-|---  1 [R] COG1832 Predicted CoA-binding protein
|||---|||||-----||------------|------|----|||||-||--||||-----||---  1 [C] COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain
|---|||||-|||----|---------||--------------------------|----------  1 [S] COG1839 Uncharacterized conserved protein
||||||||||||||||||--||--||||||||||||||----||||||||||||||----||||||  1 [J] COG1841 Ribosomal protein L30/L7E
----------------||------||----|----|||----||||||||-----|||||||||--  1 [N] COG1843 Flagellar hook capping protein
----------------||--|-||-|||||||||||||----||||||||||||||||||||||||  1 [U] COG1862 Preprotein translocase subunit YajC
--|----------||----||----|--------------------|--|-----||||----|--  1 [F] COG1864 DNA/RNA endonuclease G, NUC1
----------------||------||----|----|||----||||||||-----||||||||---  1 [N] COG1868 Flagellar motor switch protein
--||--|||--------|-------|----|-----||----------||-----|---||--|--  1 [NT] COG1871 Chemotaxis protein; stimulates methylation of MCP proteins
-----------------|----||--||||------||----------||--|--|----------  1 [T] COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH
|---||----|--|||----------||||------------|||-|--------|------|---  1 [G] COG1877 Trehalose-6-phosphatase
|-|||||||--|-|--|-----||--|||||---|-|-|---|||-|-|--|||||||-||-|--|  1 [R] COG1881 Phospholipid-binding protein
|-------|-----------|---------||||||------|||||-|-||---|----------  1 [C] COG1882 Pyruvate-formate lyase
---||||||--||--------|----||||-------|----|||----------|---|||||--  1 [I] COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit
|-------------|-||||-|-----||-------------||||||-|--||||---|||||||  1 [C] COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit
|-|--||||--||-----||||----|||||||||-||----|---|--|-|||||--||||||--  1 [M] COG1898 dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes
|||-||--||||------|||---------|----|----------|--|-----|---|-|----  1 [H] COG1903 Cobalamin biosynthesis protein CbiD
|-------------|-||||-|-----||-------------||||||-|--||||---|||||||  1 [C] COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit
-|||||--|-|-------------------|-----|------------------|----------  1 [P] COG1910 Periplasmic molybdate-binding protein/domain
||||||||--||----|||||-----||--|||--|||-------||--|-----||||||||---  1 [S] COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain
|||----|||-------||--|--------||--||------|||||-||--|--|-||----|--  1 [P] COG1918 Fe2+ transport system protein A
-|--------------||------------|---||||----|||||-||||||||----||||--  1 [R] COG1923 Uncharacterized host factor I protein
--|-||----------|--|-------||--------------------------|||--|-|---  1 [R] COG1926 Predicted phosphoribosyltransferases
--|----------||----|------||||-|---|||----||||||||||||||--||||||--  1 [HE] COG1932 Phosphoserine aminotransferase
----------------|-||----------------------|||||-||||||||||||||||--  1 [S] COG1934 Uncharacterized protein conserved in bacteria
------------------||-|----||||||--||||----|||-|--|-----|--|||-----  1 [S] COG1937 Uncharacterized protein conserved in bacteria
--||||-----|-----|-|||------|-|--|---|----|||||-|||--|||||----||--  1 [L] COG1943 Transposase and inactivated derivatives
----------------|||||||-|-|||||---|||||---||||||||||||||||||||||--  1 [I] COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase
-------------||-----------||||------------||||||||||||||----------  1 [A] COG1949 Oligoribonuclease (3'->5' exoribonuclease)
------------------||-|----||||-----|||-----------------|----------  1 [S] COG1950 Predicted membrane protein
|||---|||||-----||------------|------|----|||||-||--||||-----||---  1 [C] COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain
-|----------------------------------------||||||||||||||---|||||||  1 [U] COG1952 Preprotein translocase subunit SecB
-----------||||---------------------|-----|||||--|-----|----||||--  1 [FH] COG1953 Cytosine/uracil/thiamine/allantoin permeases
-----------|-||----|-|----|||-----|--|----|||-|--|-|---|--||||||--  1 [F] COG1957 Inosine-uridine nucleoside N-ribohydrolase
-------------|||--------------------------||||||||||-|||--------||  1 [P] COG1965 Protein implicated in iron transport, frataxin homolog
--|----|--|-|---|---|-----|||-||----||----|||||-||||-||||||-------  1 [T] COG1966 Carbon starvation protein, predicted membrane protein
|--------|||----||||||---||||||||||-||----||||||||--||||--||||||--  1 [V] COG1968 Uncharacterized bacitracin resistance protein
--|---------------|-||----||||-||||||-----|||||-|||||--|---|||||--  1 [M] COG1970 Large-conductance mechanosensitive channel
-----------------|||-|----||||||--||||----|||||-|||||--|---|||||--  1 [KT] COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases)
--||||-||-||----|-||-|-----||-----||||----|||||-||||---|||||||||--  1 [H] COG1977 Molybdopterin converting factor, small subunit
------------------||-----------------------------|--||||||||||||||  1 [S] COG1981 Predicted membrane protein
------------------|||------||||--|||||----|||||-||||---|----|-----  1 [E] COG1982 Arginine/lysine/ornithine decarboxylases
||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG1985 Pyrimidine reductase, riboflavin biosynthesis
----------------||------||----|----|||----||||||||-----|||||||||--  1 [NU] COG1987 Flagellar biosynthesis pathway, component FliQ
||||--||||------||||-|----|||-||||||||----|||||-||||||||--|---||--  1 [NOU] COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
----------------|-|||----------------|----|||||-||-|||||||||||||--  1 [H] COG1995 Pyridoxal phosphate biosynthesis protein
---------------------|--|-|||||---|||||||||||||--|||||||----|--|||  1 [S] COG2001 Uncharacterized protein conserved in bacteria
---|||--|-|-|||------|||---|||----|-||----|||||-||--||||||||||||||  1 [C] COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit
--------------------||-||-|---||||||||----|||||-||||||||||||||||--  1 [P] COG2011 ABC-type metal ion transport system, permease component
--|---|||---||||--||-------||-|-----------------|-||---|----|||---  1 [O] COG2020 Putative protein-S-isoprenylcysteine methyltransferase
|-||---------||------|----||||----||-------------|||||||------||--  1 [E] COG2021 Homoserine acetyltransferase
----------------|-||||----|||||-----||----|||||-||--||||--||||||--  1 [H] COG2022 Uncharacterized enzyme of thiazole biosynthesis
-||---|-|---|-----|||------||----|--------|--||-|------|---||-----  1 [JD] COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system
--|---------------||-|----||||------|-----|||||-||||||||----------  1 [M] COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)
--|----------||-|----|-----||||-----|-----|||||-|--|-|||----||-|--  1 [P] COG2032 Cu/Zn superoxide dismutase
|||||||||||||-----||||----|||||------|----|||-|-||-----|---|||||--  1 [H] COG2038 NaMN:DMB phosphoribosyltransferase
||--||---|-------|||-|--------|-----|------------------|----------  1 [HR] COG2045 Phosphosulfolactate phosphohydrolase and related enzymes
---|||------------||-|-----||-|---||------|||||--|-----|---||-||--  1 [P] COG2060 K+-transporting ATPase, A chain
--------|-|||---|-||------||||------------|||||-|||||--|--||||||--  1 [T] COG2062 Phosphohistidine phosphatase SixA
----------------||------------------------||||||||-----|||||||||--  1 [N] COG2063 Flagellar basal body L-ring protein
------------------||||----|||-||||||||-----------|||---|----------  1 [F] COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase
------------------|||-----|---------||----|||||-||-----|---|||||--  1 [E] COG2066 Glutaminase
|--------||||--------|-----||-------||----|||----------|---||-||--  1 [R] COG2068 Uncharacterized MobA-related protein
-------------||---|--|----||||------||-----------|-----|---||-||--  1 [P] COG2072 Predicted flavoprotein involved in K+ transport
||-|||--||||------|||---------|----|----------|--|-----|---||||---  1 [H] COG2073 Cobalamin biosynthesis protein CbiG
----------------|---------|||-||-|||||-|--|||||-||||---||||-------  1 [O] COG2077 Peroxiredoxin
|---||----||||------------|||-------||----|||-|--|-----|---||-|---  1 [R] COG2079 Uncharacterized protein involved in propionate catabolism
||||||--||||------|||------||-|----|----------|--|-----|---||||---  1 [H] COG2082 Precorrin isomerase
||||----||---------|------|----|--------------------|--|---||-|---  1 [R] COG2085 Predicted dinucleotide-binding enzymes
------------------||||----|||-|----|-|----|||-|-||-----|---||||---  1 [H] COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase
---||||||-|||-------||----||||-----|||--------|--|-----|---|||||--  1 [S] COG2096 Uncharacterized conserved protein
||----------------|||------||-|----|----------|--|-----|---||||---  1 [H] COG2099 Precorrin-6x reductase
|-|||||||-------|-||||----|||||-----||----||--|-||--||||--||-|||--  1 [H] COG2104 Sulfur transfer protein involved in thiamine biosynthesis
-||---|---||------||-|--------------||----|||||-||-----|----------  1 [S] COG2105 Uncharacterized conserved protein
--||||||--|------|||||-----||-------------|||||-||-----|---||||---  1 [H] COG2109 ATP:corrinoid adenosyltransferase
--|-||||||||||--||--||-----||---|-||------|||-|--|-----|------|---  1 [R] COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1
--|----------------------|-----||--||-----|||||--|-----|---||||---  1 [E] COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components
---|---------||---||-------||-------------------||-----|-------|--  1 [S] COG2119 Predicted membrane protein
---|---------||---||-|----|||||-----||-----------|--|--|--||||||--  1 [Q] COG2124 Cytochrome P450
------------------||-|----|||||-----------|||||-||--||||||||||||--  1 [S] COG2127 Uncharacterized conserved protein
---|---------||----|--------------|-|-----|||-|--|-----|------||--  1 [R] COG2130 Putative NADP-dependent oxidoreductases
----------|-------||-|---|-|||-------|----|||-|--|--|--|---||-||--  1 [G] COG2133 Glucose/sorbosone dehydrogenases
-----------------|--||--|-||||||||||||----|||||-||||-|||---|------  1 [R] COG2137 Uncharacterized protein conserved in bacteria
--|---|||---------|-----------------|---------|--------|---||-|---  1 [GR] COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzymes
----||--|---|--------|-----|||------------|||||-||--||||---|||||||  1 [C] COG2142 Succinate dehydrogenase, hydrophobic anchor subunit
---|-------------|||||----|---|--||-||----|||-|-||||||||--||||||--  1 [M] COG2148 Sugar transferases involved in lipopolysaccharide synthesis
|||-||||-||||----|---|----||||-|||||||----|---------|--|---|||||--  1 [R] COG2151 Predicted metal-sulfur cluster biosynthetic enzyme
---|------||-||-|-||------||||------------------||--|--|----||||--  1 [H] COG2154 Pterin-4a-carbinolamine dehydratase
---|||------------||-|-----||-|---||------|||||--|-----|---||-||--  1 [P] COG2156 K+-transporting ATPase, c chain
---|--------------||------|||-------------|||-|--|-----|----------  1 [S] COG2170 Uncharacterized conserved protein
---------|-------|--------||||||-|||||----||||||||||||||||||||||||  1 [E] COG2171 Tetrahydrodipicolinate N-succinyltransferase
-------------||------------|||------------||||--||-----|------|---  1 [Q] COG2175 Probable taurine catabolism dioxygenase
--------|-|-|-------------|||-----|-|-----|||-|--|-----|-----|----  1 [C] COG2180 Nitrate reductase delta subunit
--------|-|---------------|||-----|-|-----|||-|--|-----|-----|----  1 [C] COG2181 Nitrate reductase gamma subunit
-------------|||---||---|-|---|||||||||---|||||-||||||||---||||---  1 [K] COG2183 Transcriptional accessory protein
---||||||--||-------||----||||-------|----|||----------|---|||||--  1 [I] COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)
--------------------|----||---||||||||-|||||||||||||---|-------|--  1 [G] COG2190 Phosphotransferase system IIA components
------------------||-------|||------------|||||-||--||||---|||||--  1 [P] COG2193 Bacterioferritin (cytochrome b1)
--||--|||--------|-|----||----|-----||----|||||-||--|--|--|||-||--  1 [NT] COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain
------------------||-|-----||-|---||------|||||-||-----|--|||-||--  1 [T] COG2205 Osmosensitive K+ channel histidine kinase
-|------------------|---|-----------------|||||---||---|---||||---  1 [R] COG2215 ABC-type uncharacterized transport system, permease component
---|||------------||-|-----||-|---||------|||||--|-----|--|||-||--  1 [P] COG2216 High-affinity K+ transport system, ATPase chain B
-----------|-||------|----||||-------|----|||||-||-----|---|||||--  1 [C] COG2224 Isocitrate lyase
----------||-|-------|----||||-------|----|||||-||-----|---|||||--  1 [C] COG2225 Malate synthase
--|-||----||-||-||||||||--||||----||||----|||||-||-|||||||||||||||  1 [H] COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis
-------------||---||-|--------------------|||||-||-|||||---|||||||  1 [H] COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase
-------|------|--|--||----|---||||||||----|||||-||||-|||---|||----  1 [F] COG2233 Xanthine/uracil permeases
--|||||||-|||||----|----|||--------------------------||||||-------  1 [R] COG2236 Predicted phosphoribosyltransferases
||||||--||||------|||-----|||-|----|----------|--|-----|---||||---  1 [H] COG2241 Precorrin-6B methylase 1
||||||--||||------|||------||-|----|----------|--|-----|---||||---  1 [H] COG2243 Precorrin-2 methylase
||||||||||-|-----|-|||----|---||||||||----|||||-||||||||---|||||--  1 [R] COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
---||||||||||-----||------||||||-||||-----|---|--|-----|------||--  1 [S] COG2246 Predicted membrane protein
-----------------||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG2255 Holliday junction resolvasome, helicase subunit
-------------||--|--||----|||||||||||||---|||||-||||||||||||||||--  1 [L] COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
---------------------|----|||-|---||||----|||-|--||----|--||-|----  1 [S] COG2258 Uncharacterized protein conserved in bacteria
-------------------|-|----||||-||||-|-----|||||--|-----|---|||||--  1 [S] COG2261 Predicted membrane protein
-|||--||-||||---||||||||--||||||||||||----|||||-||-|||||---|||||--  1 [R] COG2262 GTPases
----------------||||||--------||||||||----|||||-||||||||||||||||--  1 [J] COG2264 Ribosomal protein L11 methylase
------||-----||-||||||||--|||-||||||||----|||||-||||||||--||||||--  1 [J] COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase
--------------|------|----|||-|---|-|---------|--------|-------|--  1 [I] COG2272 Carboxylesterase type B
---|-------||-------||----|||--||---------|||||-|||----|---|||||--  1 [G] COG2301 Citrate lyase beta subunit
------------------|--|-----|||-------------------|-----|---||-||--  1 [S] COG2307 Uncharacterized protein conserved in bacteria
-----------|------|--|-----|||-------------------|-----|---||-||--  1 [S] COG2308 Uncharacterized conserved protein
--------------------||----|----|||-||-----|||||--|-----|---|--||--  1 [S] COG2315 Uncharacterized protein conserved in bacteria
---------------------|----|||---|---------|||||--|-|---|---||||---  1 [R] COG2321 Predicted metalloprotease
--|---------------||-|----|||-------------------||-----|--||||||--  1 [S] COG2326 Uncharacterized conserved protein
---|||-----||--------|----||||----||||-----------|-----|---||||---  1 [R] COG2329 Conserved protein involved in polyketide biosynthesis related to monooxygenase
-----------------|---|-----|||-------------------------|----------  1 [S] COG2331 Uncharacterized protein conserved in bacteria
---|---------------|-|--------||||||||----|||||-||||||||----------  1 [R] COG2333 Predicted hydrolase (metallo-beta-lactamase superfamily)
-------------------|-|---------------|----|||--------|||---|------  1 [T] COG2336 Growth regulator
-|-------|-------|--||---------------------------------|----------  1 [G] COG2342 Predicted extracellular endo alpha-1,4 polygalactosaminidase or related polysaccharide hydrolase
------------------||-|-----||--------------------------|----|-|---  1 [S] COG2343 Uncharacterized protein conserved in bacteria
------------------|--|----||||----|-||-----------------|--||||||--  1 [R] COG2346 Truncated hemoglobins
------------------||||----|---|-----|-----|||||-||||-|||---|||||--  1 [S] COG2350 Uncharacterized protein conserved in bacteria
--------------|------|--------------||----|||-|--|-----|--||||||--  1 [R] COG2351 Transthyretin-like protein
------------------||-|----|--|--||--------|||||-||||-|||-------|--  1 [C] COG2352 Phosphoenolpyruvate carboxylase
------||--|||-|------|||-----------|-|-----------|-----|---|||||--  1 [E] COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog
------------------||-|--------------------|||||-||--||||--||||||--  1 [O] COG2360 Leu/Phe-tRNA-protein transferase
------||----|--------|-------------||------------------|------|---  1 [E] COG2362 D-aminopeptidase
-------------||------|-----||--|---|---------|---|-----|---|---|--  1 [T] COG2365 Protein tyrosine/serine phosphatase
----||--|-|||-----||-|---------------------------|-----|-----|-|--  1 [R] COG2366 Protein related to penicillin acylase
----------------|-||-|---------------------------|-----|---|--|---  1 [O] COG2370 Hydrogenase/urease accessory protein
------------------||-|----|-------|--||----|||---||----|||-||||---  1 [O] COG2371 Urease accessory protein UreE
---------------------|----|--------|||----|||||--------|----|-|---  1 [R] COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC
-----------------|-|||--------------------|||||--|-||--|---||-||||  1 [R] COG2373 Large extracellular alpha-helical protein
---------------------|----|||-------------|||-|-||-----|---||-----  1 [P] COG2375 Siderophore-interacting protein
---------|--------||-|--------------------|||||-||||||||---|||||--  1 [O] COG2377 Predicted molecular chaperone distantly related to HSP70-fold metalloproteases
--------------------||----|||||---||||----|---|-||--|-||--||||||--  1 [K] COG2378 Predicted transcriptional regulator
---------------------|--------||||||||----|||||-|--|---|---||||---  1 [K] COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
-------------------|||----|---||||||||||--|||||-|----|||----------  1 [S] COG2501 Uncharacterized conserved protein
------||------|--|-|----------------------|||||-|------|--|---||--  1 [E] COG2515 1-aminocyclopropane-1-carboxylate deaminase
------------------||--------------|-|------------|-----|--||--|--|  1 [V] COG2602 Beta-lactamase class D
----------------|-||----------|------------------|---|||--||||||--  1 [R] COG2607 Predicted ATPase (AAA+ superfamily)
--||||--|--||||-||||||----|---|||-|||||-------|--|||-|||||-|||----  1 [P] COG2608 Copper chaperone
---------------------|----||||------------||||||||||||||------||--  1 [C] COG2609 Pyruvate dehydrogenase complex, dehydrogenase (E1) component
-|--------------|-------------|-----------------||-----|--|-------  1 [P] COG2703 Hemerythrin
------------------|-----------|-----||-----------|-----|----------  1 [R] COG2715 Uncharacterized membrane protein, required for spore maturation in B.subtilis.
-------------------|-|--|-----|-----------|||||--|-|---|--||||-|--  1 [S] COG2717 Predicted membrane protein
------||-----||--|-|----------|-----||--------------|--|----------  1 [G] COG2730 Endoglucanase
----------------||------------|-----||----|||||-||-----|----------  1 [KNU] COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor)
---|-------|---------|----|---|---||||----------|---|--|---|||||--  1 [Q] COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis
--------------|---||-|-----||-------------------||-----|---|||||--  1 [R] COG2802 Uncharacterized protein, similar to the N-terminal domain of Lon protease
----------------||||||--------|-----------|||||-||--||||----------  1 [NU] COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT
---------------------|----|---|--|-||-----|||-|--|-----|--|--|----  1 [P] COG2807 Cyanate permease
-------------|-------|--------------||-----------|--|--|------||--  1 [K] COG2808 Transcriptional regulator
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG2812 DNA polymerase III, gamma/tau subunits
--------------------------||||-|||||-|----|||||-||||-|||---|||||--  1 [L] COG2818 3-methyladenine DNA glycosylase
------------------||----------------------||||||||||-|||---|||||--  1 [M] COG2821 Membrane-bound lytic murein transglycosylase
--------------------------|----|||-|------|||||-||||-|||||||||||--  1 [P] COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism
----------------||---|||||----------------|||||-||||-|||-------|||  1 [M] COG2825 Outer membrane protein
--------------------------|||--|-|---|-|--|||--------|||---||--|--  1 [L] COG2826 Transposase and inactivated derivatives, IS30 family
------------------------------------|-----|||---||--||||---||-|---  1 [S] COG2828 Uncharacterized protein conserved in bacteria
--------------------------------------------------||-|||--||||----  1 [S] COG2833 Uncharacterized protein conserved in bacteria
-|||----|-------|----|--||----|-----||----|||||-||||||||||||||||||  1 [M] COG2834 Outer membrane lipoprotein-sorting protein
--||------|||-------------||||------------|||||-||-|||||----||||--  1 [S] COG2835 Uncharacterized conserved protein
---|---------------|----------|-----------------||---||||||-------  1 [S] COG2836 Uncharacterized conserved protein
-------------------|-|----|||-----|||-----|||||-||-|-|||------|---  1 [P] COG2837 Predicted iron-dependent peroxidase
------------------------|-----------------||||||||||||||---|||||--  1 [S] COG2840 Uncharacterized protein conserved in bacteria
--------------------------|||-------------|||||-||||-|||---|||||--  1 [O] COG2844 UTP:GlnB (protein PII) uridylyltransferase
------------------------------|---|-------|||||---|--|||----|-----  1 [D] COG2846 Regulator of cell morphogenesis and NO signaling
----------|-----|----|----|---------------------||-|-|||--||||||||  1 [S] COG2847 Uncharacterized protein conserved in bacteria
------------------------------------|-----|||||--|||||||----------  1 [S] COG2850 Uncharacterized conserved protein
------------------------------------------|||||-||||||||--|----|||  1 [Q] COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component
--------|-----------|-----|----|||||------|||||--|||-|||--||||||--  1 [S] COG2855 Predicted membrane protein
-------------------|||---|-||-|--|||||--------------||-|-----|----  1 [E] COG2856 Predicted Zn peptidase
---|------||---------|----|----||---||----|||||-||||---|--||||||--  1 [S] COG2860 Predicted membrane protein
--|-------------|----|--------------------|||-||||||---|||||---|--  1 [S] COG2862 Predicted membrane protein
--|-----|-------|-------------------------|||||-||||---|--|-|-----  1 [C] COG2864 Cytochrome b subunit of formate dehydrogenase
--|----------||---|-----------------||----|||||--|---|||-------|--  1 [E] COG2866 Predicted carboxypeptidase
-------------||---------------------------|||||-||-|||||---|||||||  1 [I] COG2867 Oligoketide cyclase/lipid transport protein
--|-||||--||||---|--||--------|------|----------||-----|---||||---  1 [R] COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain
||||||--||||------|||------||-|----|----------|--|-----|---||||---  1 [H] COG2875 Precorrin-4 methylase
----------------|---|-||------------------|||||-||||||||||||||||||  1 [M] COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase
--|--------------|--|---------------------||||||||||||||----------  1 [C] COG2878 Predicted NADH:ubiquinone oxidoreductase, subunit RnfB
------------------------------------------|||||--|---|||--|-------  1 [S] COG2879 Uncharacterized small protein
-----------------|------|-----|-----||----||||||||-----|----------  1 [NUO] COG2882 Flagellar biosynthesis chaperone
--|---------|-----------|-||||-------------------------|||||||||||  1 [L] COG2887 RecB family exonuclease
-------------------|----|------|-|||||----|||||-|||||--|----------  1 [M] COG2891 Cell shape-determining protein
--------------------|---------||||-||-----|||||----|||||---|||||--  1 [G] COG2893 Phosphotransferase system, mannose/fructose-specific component IIA
----------------||||||--------|----|||----||||||||--||||||-||||---  1 [D] COG2894 Septum formation inhibitor-activating ATPase
--------------------------|||-|-----------||||||||--||||---|||||--  1 [P] COG2895 GTPases - Sulfate adenylate transferase subunit 1
|||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||--  1 [H] COG2896 Molybdenum cofactor biosynthesis enzyme
|--|------|||||-|--|-|----||||-------|----|||||-||-----|---|||||--  1 [P] COG2897 Rhodanese-related sulfurtransferase
--|-----------------------||||-|--|||------------|--|--|---|||||--  1 [S] COG2898 Uncharacterized conserved protein
------------------------------------------||||||||||||||----------  1 [KL] COG2901 Factor for inversion stimulation Fis, transcriptional activator
------------------------------------------|||||-|||||--|--------||  1 [S] COG2904 Uncharacterized protein conserved in bacteria
------------------|---------|-------------||-||-||--||||-------|--  1 [P] COG2906 Bacterioferritin-associated ferredoxin
-------------------------------|-|-||-----------||-----|--|||-|---  1 [R] COG2910 Putative NADH-flavin reductase
------------------------------------------||||||||||||||---|||||--  1 [S] COG2911 Uncharacterized protein conserved in bacteria
-------------------|--||------------------|||||||||||--|-------|--  1 [S] COG2912 Uncharacterized conserved protein
------------------------------------------||||||||||||||---|||||||  1 [J] COG2913 Small protein A (tmRNA-binding)
------------------------------------------||||||||||||||----------  1 [S] COG2914 Uncharacterized protein conserved in bacteria
------------------------------------------||||||||||-|||----||||||  1 [D] COG2917 Intracellular septation protein A
------------------------||||||-|||||||----||||||||||||||---|||||||  1 [D] COG2919 Septum formation initiator
------------------------------------------||||||||||||||----------  1 [S] COG2921 Uncharacterized conserved protein
------------------------------------------||||||||||||||----------  1 [CO] COG2924 Fe-S cluster protector protein
------------------------------------------|||||||||||--|----------  1 [L] COG2925 Exonuclease I
------------------------------------------|||||-||||||||---|||||||  1 [L] COG2927 DNA polymerase III, chi subunit
---|---------------||-||-------------|-----------|--||||---||-|---  1 [S] COG2928 Uncharacterized conserved protein
-------------||--|----------------------------------|--|----------  1 [S] COG2930 Uncharacterized conserved protein
-------------||---------------------------------||--|--|--||||||--  1 [O] COG2935 Putative arginyl-tRNA:protein arginylyltransferase
-------------||---------------------------|||||-||||||||---|||||||  1 [S] COG2938 Uncharacterized conserved protein
-------------||------|------------------------------|--|-------|--  1 [E] COG2939 Carboxypeptidase C (cathepsin A)
--|----------|||------||----------------------------|--|------|---  1 [R] COG2940 Proteins containing SET domain
-------------||----------------------------------|--|--|-------|||  1 [H] COG2941 Ubiquinone biosynthesis protein COQ7
------------------||----------------------|||-|-----|--|---|||||--  1 [G] COG2942 N-acyl-D-glucosamine 2-epimerase
------------------------------------------|||-|-||--|--|-------|--  1 [M] COG2943 Membrane glycosyltransferase
-------------------|----------------------|||-|-|---||||---||----|  1 [K] COG2944 Predicted transcriptional regulator
---|----|----------------------------------------|--||||---|||||||  1 [R] COG2945 Predicted hydrolase of the alpha/beta superfamily
--------------|---||-|---------------------------|--|--|---||||---  1 [S] COG2947 Uncharacterized conserved protein
------------------------------------------|||||-|-||||||----------  1 [G] COG2956 Predicted N-acetylglucosaminyl transferase
-------------------------------------------------|--|--||||-------  1 [S] COG2958 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||-|||----------  1 [H] COG2959 Uncharacterized enzyme of heme biosynthesis
------------------------------------------|||||-||--||||---||||---  1 [S] COG2960 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||||||---|||||-|  1 [R] COG2961 Protein involved in catabolism of external DNA
--------------------------|-------||||----|||||-||||---|---|||||--  1 [R] COG2962 Predicted permeases
--------------------|-----------|---------|||||-||||---|--|-|-----  1 [S] COG2964 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||-|||----------  1 [L] COG2965 Primosomal replication protein N
---------------------|--------------------|||||-||--|--|---|||||--  1 [P] COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport
------------------------------------------|||||-||||||||----------  1 [R] COG2969 Stringent starvation protein B
--------------------|---------|-||||||----------||--|--|----------  1 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain
------------------------------------------|||||-||||||||----------  1 [L] COG2974 DNA recombination-dependent growth factor C
------------------------------------------|||||-|||--|||----------  1 [S] COG2975 Uncharacterized protein conserved in bacteria
------------------------------------------||||||||||||||----------  1 [S] COG2976 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||||||----------  1 [M] COG2980 Rare lipoprotein B
------------------------------------------|||||-||---|||----|||-||  1 [M] COG2982 Uncharacterized protein involved in outer membrane biogenesis
----------------|---|-||--|-----||--------------||-----|---||||-||  1 [R] COG2984 ABC-type uncharacterized transport system, periplasmic component
---|||--------------||----------|-|-||-------|--||-----|---|||||--  1 [E] COG2987 Urocanate hydratase
------------------|-----------------------------|----|-|----|-----  1 [O] COG2994 ACP:hemolysin acyltransferase (hemolysin-activating protein)
|---------|-------------------------------------|------|--|-------  1 [H] COG2998 ABC-type tungstate transport system, permease component
------------------------------------------|||||-||---|||----------  1 [S] COG3009 Uncharacterized protein conserved in bacteria
------------------||--------------|-||-------|--||--|--|------||--  1 [S] COG3011 Uncharacterized protein conserved in bacteria
---------------------|----|---------------|||||-||||-|-|----------  1 [S] COG3012 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||||||----------  1 [M] COG3017 Outer membrane lipoprotein involved in outer membrane biogenesis
----------------|---|-----|-----||--------|||||-||||-|||--|----|-|  1 [S] COG3022 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||-|||----||||--  1 [S] COG3024 Uncharacterized protein conserved in bacteria
--|---------------------------------------|||||-||||---|------||--  1 [S] COG3025 Uncharacterized conserved protein
------------------------------------------|||||-||||---|----------  1 [T] COG3026 Negative regulator of sigma E activity
------------------------------------------|||||-||||||||----------  1 [S] COG3028 Uncharacterized protein conserved in bacteria
--------|---------------------------------|||||-|----|||------|---  1 [R] COG3042 Putative hemolysin
------------------------------------------|||||-||---|||---||||---  1 [S] COG3045 Uncharacterized protein conserved in bacteria
---------------------------------------------|--||||||||----------  1 [NU] COG3063 Tfp pilus assembly protein PilF
------------------------------|--|||------|||||-||||-|-|----|-||-|  1 [K] COG3070 Regulator of competence-specific genes
------------------------------------------|||||-||||||||----------  1 [H] COG3071 Uncharacterized enzyme of heme biosynthesis
------------------------------------------|||||-|||||--|----------  1 [T] COG3073 Negative regulator of sigma E activity
------------------------------------------|||||-||||||||----------  1 [D] COG3087 Cell division protein
------------------------------------------|||||-|-||||||----------  1 [R] COG3113 Predicted NTP binding protein (contains STAS domain)
------------------------------------------|||||||||||--|----------  1 [D] COG3116 Cell division protein
------------------------------------------|||||-||||||||----------  1 [S] COG3117 Uncharacterized protein conserved in bacteria
--------------------------||||------------|||||-|||||--|---|||||--  1 [O] COG3118 Thioredoxin domain-containing protein
------------------------------------------|||||-||-----|----------  1 [S] COG3123 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||-----|---|||||--  1 [Q] COG3127 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component
------------------------------------------|||||--|||---|----------  1 [M] COG3133 Outer membrane lipoprotein
-----------------|------------|-----||----||||||||-----|----------  1 [N] COG3144 Flagellar hook-length control protein
--------------|----|------||||------------|||-|-||--|--|---|||||--  1 [L] COG3145 Alkylated DNA repair protein
------------------||-----------------------------|--|--|---|||||--  1 [S] COG3146 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||--|--|----------  1 [S] COG3147 Uncharacterized protein conserved in bacteria
------------------------------------------|-----||-----|----------  1 [U] COG3149 Type II secretory pathway, component PulM
------------------------------------------|||||-||-|---|----------  1 [R] COG3150 Predicted esterase
------------------------------------------|||||-||-----|---|||----  1 [I] COG3154 Putative lipid carrier protein
------------------------------------------|--|--||--|--|------||--  1 [U] COG3156 Type II secretory pathway, component PulK
------------------------------------------|||||-||-----|---|--|---  1 [S] COG3157 Hemolysin-coregulated protein (uncharacterized)
------------------------------------------|||||-||-||--|-------|--  1 [S] COG3159 Uncharacterized protein conserved in bacteria
|||-----||-----------------|||------------|||||-||-|-|||----------  1 [H] COG3161 4-hydroxybenzoate synthetase (chorismate lyase)
------------------------------------------|||||-||--|--|----------  1 [S] COG3164 Predicted membrane protein
------------------------------------------|||||-||-|||||----------  1 [S] COG3165 Uncharacterized protein conserved in bacteria
------------------||----------------------|||||-||--||||------|---  1 [NU] COG3166 Tfp pilus assembly protein PilN
------------------------------------------------||--||||----------  1 [NU] COG3167 Tfp pilus assembly protein PilO
------------------------------------------------||--||||----------  1 [NU] COG3168 Tfp pilus assembly protein PilP
--||-----------------|-----||--|---|||-----------|-----|---||-||-|  1 [R] COG3173 Predicted aminoglycoside phosphotransferase
|-||-----|--|---|--------------------------------|-----|----|-|---  1 [S] COG3174 Predicted membrane protein
-------------||----------------------------------|-----|---|||||||  1 [O] COG3175 Cytochrome oxidase assembly factor
-------------------|-------||-------------------||-----|---|||||--  1 [R] COG3176 Putative hemolysin
--||------------|--||-----|-----|-||-------|||---|-|-|||||-||-|--|  1 [S] COG3177 Uncharacterized conserved protein
-------------------------------------------------|--||||---|||||--  1 [R] COG3178 Predicted phosphotransferase related to Ser/Thr protein kinases
--------------------------|-------|--|----------||---|||---|---|--  1 [S] COG3182 Uncharacterized iron-regulated membrane protein
-----------------------|------------------------||-----|------||--  1 [E] COG3186 Phenylalanine-4-hydroxylase
--|---------------|-||----|---------------|||||-||-----||||||||---  1 [O] COG3187 Heat shock protein
----||-----|--------------|||-----|-------|||-|--|-----|---||||---  1 [S] COG3189 Uncharacterized conserved protein
----------------------||------------||----||||||||-----|----------  1 [N] COG3190 Flagellar biogenesis protein
------||---|---------|----||||-------------------|-----|---|||||--  1 [EQ] COG3191 L-aminopeptidase/D-esterase
----------||------|----------------|------|---|--|-----|---|-|||--  1 [R] COG3193 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol
---------------------|----|---------||-----------|-----|---|||||--  1 [S] COG3195 Uncharacterized protein conserved in bacteria
------------------------------------------------||---||||||-|-||--  1 [P] COG3197 Uncharacterized protein, possibly involved in nitrogen fixation
----------------||||----------------------|||-|-||-||--|---|||||--  1 [M] COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis
-------------------|-------||||-----||-------|---|-----|---|--|---  1 [Q] COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis
------------------------------------------------||---|||---|||----  1 [P] COG3213 Uncharacterized protein involved in response to NO
-------------------------------------------------|--||||----------  1 [NU] COG3215 Tfp pilus assembly protein PilZ
------------------------------|------------------|||-|||----|--|--  1 [S] COG3220 Uncharacterized protein conserved in bacteria
------------------||----------------------|||||--|-----|----------  1 [S] COG3228 Uncharacterized protein conserved in bacteria
---------------------|-----------------------||-||-|---|-----|----  1 [E] COG3232 5-carboxymethyl-2-hydroxymuconate isomerase
-|----||------------------|||--------------------|-----|----------  1 [R] COG3233 Predicted deacetylase
-----------------|------------------------|||----|-----|----------  1 [S] COG3234 Uncharacterized protein conserved in bacteria
-------------------|--------------------------|-||-||--|----------  1 [IR] COG3240 Phospholipase/lecithinase/hemolysin
------------------------------------------|||||-||--|--|-----||---  1 [S] COG3242 Uncharacterized protein conserved in bacteria
--------|---------|--------|||------------------||-----|---||-||||  1 [I] COG3243 Poly(3-hydroxyalkanoate) synthetase
--------|-----------||-----|---------------------|-----|---||-|---  1 [S] COG3246 Uncharacterized conserved protein
--|----------------|-------||--|--||------||||---|-----|----|||---  1 [S] COG3247 Uncharacterized conserved protein
----------||------|------------------------------|---|||---|||----  1 [P] COG3256 Nitric oxide reductase large subunit
------------------|------------------------------|-----|--|--|----  1 [C] COG3258 Cytochrome c
------------------|-----------------------|||||--|||---|---|||||--  1 [M] COG3264 Small-conductance mechanosensitive channel
|-|----------------------------------------------|---|||--|-------  1 [R] COG3271 Predicted double-glycine peptidase
-------------------------------|----------|||||-|------|--------|-  1 [S] COG3274 Uncharacterized protein conserved in bacteria
--------------------|---------||||||||----|||||-||--|--|---|||||--  1 [KT] COG3279 Response regulator of the LytR/AlgR family
-----------|-------|-|----|||-----------------|--|-----|----|-----  1 [G] COG3280 Maltooligosyl trehalose synthase
------------|-------------|||--------------------|-----|----------  1 [G] COG3281 Uncharacterized protein, probably involved in trehalose biosynthesis
-------------------|----------|-----||----|-----||-----|---|||||--  1 [QK] COG3284 Transcriptional activator of acetoin/glycerol metabolism
---------------------|--------------------------|---|--|-------|--  1 [S] COG3295 Uncharacterized protein conserved in bacteria
------------------|-----------------|---------|--|-----|---||-||--  1 [T] COG3300 MHYT domain (predicted integral membrane sensor domain)
------------------------------------------------||---|||----------  1 [S] COG3308 Predicted membrane protein
------------------------------------------------|---||||----------  1 [S] COG3310 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||-|||----------  1 [M] COG3317 Uncharacterized lipoprotein
--|-----------------------|||--------|--------|-||-|---|---|||||--  1 [R] COG3324 Predicted enzyme related to lactoylglutathione lyase
-------------|-----------------------|-----------|-----|----------  1 [S] COG3332 Uncharacterized conserved protein
--------------------|-----|----------|--------|-||-|---|---||-----  1 [S] COG3333 Uncharacterized protein conserved in bacteria
|-|---------------||----------|-----||-----------------|---|||||--  1 [S] COG3339 Uncharacterized conserved protein
-------------||-----------||||-------------------|-----|---|||||||  1 [S] COG3346 Uncharacterized conserved protein
---|-----------------------||--------------------|-----|----|-----  1 [S] COG3360 Uncharacterized conserved protein
|-|-||------|------------------------------------------|------|---  1 [S] COG3369 Uncharacterized conserved protein
----|------|--|------------||-----|----------||--------|||--------  1 [P] COG3376 High-affinity nickel permease
---|--------------||-----------------------------|-----|----------  1 [R] COG3380 Predicted NAD/FAD-dependent oxidoreductase
---|-------|------------------------------|||||-|-||---|----------  1 [R] COG3381 Uncharacterized component of anaerobic dehydrogenases
---------||||-----------------|||---||--------|--|-----|------|---  1 [S] COG3382 Uncharacterized conserved protein
--|-|------|--|---------------|-----------|||||--|-|---|-------|--  1 [S] COG3384 Uncharacterized conserved protein
-||-||-----|-||----|------|||-|------------------------|---|--||--  1 [G] COG3387 Glucoamylase and related glycosyl hydrolases
--|---------------||-|----|||||-----||----------|------|---||||---  1 [M] COG3409 Putative peptidoglycan-binding domain-containing protein
-----------------------------------------------|-|--|--|---|------  1 [S] COG3416 Uncharacterized protein conserved in bacteria
----------|--------------------------------------|---|||----||----  1 [P] COG3420 Nitrous oxidase accessory protein
---|||----|||--------|-----||--------------------------|----|||---  1 [S] COG3427 Uncharacterized conserved protein
------------------|------------------------------|-----|---||-|---  1 [T] COG3448 CBS-domain-containing membrane protein
---|--------------------------|--------|------|-----|--|||-|||||||  1 [U] COG3451 Type IV secretory pathway, VirB4 components
-------------------------------------------||||-||-----|---|--|---  1 [S] COG3455 Uncharacterized protein conserved in bacteria
---------------------|---------------|----|------------|----|-----  1 [Q] COG3460 Uncharacterized enzyme of phenylacetate metabolism
|-|||--------------|||--------||-----|--------|------|||----|||---  1 [R] COG3467 Predicted flavin-nucleotide-binding protein
-------------------------------------------------|-|-|||----------  1 [S] COG3471 Predicted periplasmic/secreted protein
------||---||------------------------------------------|----|-|---  1 [Q] COG3473 Maleate cis-trans isomerase
------------------|------------------------------|-----|------|---  1 [O] COG3484 Predicted proteasome-type protease
--------------|------------------------------|---|-----|--|---||--  1 [R] COG3491 Isopenicillin N synthase and related dioxygenases
-------------------|-----------------------||||--|--|--|---|--|---  1 [R] COG3497 Phage tail sheath protein FI
-------------------------------------------||-|--|--|--|----------  1 [R] COG3498 Phage tail tube protein FII
-------------------------------------------||-|--|--|--|---|------  1 [R] COG3499 Phage protein U
-------------------|----------------------|||-|--|--|--|---|--|---  1 [R] COG3500 Phage protein D
|-|-----|----------------------------------------|-----|---|||||--  1 [S] COG3503 Predicted membrane protein
----------------------------------------------------|--|||-|||||||  1 [U] COG3504 Type IV secretory pathway, VirB9 components
-------------------|----------|---------------|-----|--|||-||-|-||  1 [U] COG3505 Type IV secretory pathway, VirD4 components
-----------|------------------------------------||-----|----|-||--  1 [Q] COG3508 Homogentisate 1,2-dioxygenase
--------------------------||||-------------------|-----|---||-||--  1 [Q] COG3509 Poly(3-hydroxybutyrate) depolymerase
-------------------------------------------||||-||-----|---|--|---  1 [S] COG3515 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  1 [S] COG3516 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  1 [S] COG3517 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  1 [S] COG3518 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  1 [S] COG3519 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  1 [S] COG3520 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|------|---  1 [S] COG3521 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  1 [S] COG3522 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  1 [S] COG3523 Uncharacterized protein conserved in bacteria
-------------------------------------------|-||-||-----|----------  1 [S] COG3530 Uncharacterized protein conserved in bacteria
-------------------------------------------------|---|||---||||---  1 [S] COG3536 Uncharacterized protein conserved in bacteria
-|-----------------|----------|-----|------------|-----|------|---  1 [R] COG3541 Predicted nucleotidyltransferase
-------------|----|--------------||--------------------|---||-||--  1 [S] COG3542 Uncharacterized conserved protein
--------------------|-----|---------------|||---|-|--|-|---||-||--  1 [R] COG3550 Uncharacterized protein related to capsule biosynthesis enzymes
|-----------|--------------||--------------------------|----|-|---  1 [R] COG3552 Protein containing von Willebrand factor type A (vWA) domain
-------------------|--------------------------|--|--|--|-----||---  1 [O] COG3555 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases
------------------|------------------------------|-----|------|---  1 [S] COG3556 Predicted membrane protein
--|----------------|-----------------------------|||---|------|---  1 [H] COG3585 Molybdopterin-binding protein
----------------|-------|-----------------|||-|-||-----|----|-|---  1 [KT] COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains
-||||||||-|||------|-------||--------------||||-----|--|---||-||--  1 [K] COG3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain
--|-----------|----------|-----|------|----------|-----|---|--||--  1 [F] COG3613 Nucleoside 2-deoxyribosyltransferase
---------------------------------------------|---|-----|--|||||---  1 [R] COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold
--|---------------|-|------||-||||-||------------|-----|---||||---  1 [S] COG3619 Predicted membrane protein
-------------------|-------------------------||--|--|--|------|---  1 [R] COG3628 Phage baseplate assembly protein W
-------------------------------||-|-|-----|||-|--|--|--|-------|--  1 [O] COG3634 Alkyl hydroperoxide reductase, large subunit
---------------------------------------------|----|-|--|----|--|--  1 [K] COG3636 Predicted transcriptional regulator
---------------------|---------------------------|-----|-------|--  1 [S] COG3644 Uncharacterized protein conserved in bacteria
-------|-------------------||--------------------------|-------|--  1 [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase
-------------------|-------------------------|----|-|--|----|--|--  1 [S] COG3657 Uncharacterized protein conserved in bacteria
------------------------------------------------|----|||-------|--  1 [C] COG3658 Cytochrome b
------------------|------------------------------|-----|-------|--  1 [M] COG3659 Carbohydrate-selective porin
---------------------------||--------------------|-----|-------|--  1 [S] COG3662 Uncharacterized protein conserved in bacteria
--|-----------|------|--------------------|||-|----|-|||--|----|--  1 [L] COG3663 G:T/U mismatch-specific DNA glycosylase
-------------------------------------------------|--|--|-------|--  1 [P] COG3667 Uncharacterized protein involved in copper resistance
-------------------|-|-----||--------------|||--||--|--|---|||||--  1 [R] COG3668 Plasmid stabilization system protein
------------------||-------||--------------------------|-------|--  1 [Q] COG3670 Lignostilbene-alpha,beta-dioxygenase and related enzymes
-----------------------------------------------------|||-------|||  1 [S] COG3671 Predicted membrane protein
------------------||----------------------|||||-||----||----|-----  1 [UNTP] COG3678 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein
-------------------|-----------------------------|---|||---|-|-|--  1 [S] COG3686 Predicted membrane protein
---------------------------||--------------------|-----|-------|--  1 [R] COG3687 Predicted metal-dependent hydrolase
----------------------------------------------------|--|---|--||--  1 [U] COG3701 Type IV secretory pathway, TrbF components
-------------||---------------------|-----|||----------|---|||||--  1 [P] COG3703 Uncharacterized protein involved in cation transport
----------------|-||-|--------||---|||-----------|---|||---|||||--  1 [E] COG3705 ATP phosphoribosyltransferase involved in histidine biosynthesis
--------------------|------||||----|-------------|-----|---||-||--  1 [T] COG3707 Response regulator with putative antiterminator output domain
---------------------------||-------------|||||-|------|-----|||--  1 [S] COG3714 Predicted membrane protein
--------------------------|--------|||-------||--------|---|||||--  1 [G] COG3718 Uncharacterized enzyme involved in inositol metabolism
-------------------------------------------|||---|-----|----|-|---  1 [P] COG3720 Putative heme degradation protein
------------------------------------------|||-|-------||----|--|--  1 [L] COG3727 DNA G:T-mismatch repair endonuclease
------------------------------------------|---|--------|---|||||--  1 [G] COG3734 2-keto-3-deoxy-galactonokinase
----------------------------------------------------||||---|||||--  1 [S] COG3737 Uncharacterized conserved protein
---------------------------||--|---|-------||-|--------|---|---|--  1 [R] COG3740 Phage head maturation protease
-------------------------------------------------|-----|---|||||--  1 [S] COG3748 Predicted membrane protein
------------------------------------------|||----|-----|----|||---  1 [S] COG3753 Uncharacterized protein conserved in bacteria
--------------------|-----------|---------||||---|-----|---||||---  1 [S] COG3758 Uncharacterized protein conserved in bacteria
------------------------|--------------------------|---|-----|||--  1 [S] COG3762 Predicted membrane protein
------------------------------------||----|||-|--------|---|---|--  1 [S] COG3766 Predicted membrane protein
-------------||-----|---------------------------|--|---|---|------  1 [M] COG3774 Mannosyltransferase OCH1 and related enzymes
------------------||----------------------|||-|--------|------|---  1 [S] COG3781 Predicted membrane protein
--------------|-------------------------------|--|-----|---|||||--  1 [S] COG3791 Uncharacterized conserved protein
-------------------------------------------------|-----|---||-||--  1 [S] COG3795 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|---|||||--  1 [S] COG3803 Uncharacterized protein conserved in bacteria
------------------------------------------------|------|------||--  1 [T] COG3806 Anti-sigma factor
-------------------------------------------------|-----|------||--  1 [S] COG3812 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|---||-||--  1 [S] COG3813 Uncharacterized protein conserved in bacteria
--------------------------------||-----------|---------|--|----|--  1 [S] COG3817 Predicted membrane protein
--------------------------------||-----------|---------|--|----|--  1 [S] COG3819 Predicted membrane protein
-------------------|-----------------------------|-----|------||--  1 [S] COG3825 Uncharacterized protein conserved in bacteria
---------------------------||--------------------------|------||--  1 [S] COG3826 Uncharacterized protein conserved in bacteria
----------------|-------------|----|||----|||-|--|-----|----------  1 [KT] COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
-------------------|----------|-----------------|------|----|-||--  1 [S] COG3837 Uncharacterized conserved protein, contains double-stranded beta-helix domain
----------------------------------------------------|--|---||-||||  1 [U] COG3838 Type IV secretory pathway, VirB2 components (pilins)
---------------------------------|------------------|--|||-|--|---  1 [U] COG3843 Type IV secretory pathway, VirD2 components (relaxase)
---|---------|-------|---------------------------|-----|------|---  1 [E] COG3844 Kynureninase
---|--|||-|-|----|-|-|--||----||||-||-||||-------|-----|---||||---  1 [R] COG3845 ABC-type uncharacterized transport systems, ATPase components
----------------------------------------------------|--|||-|--|---  1 [U] COG3846 Type IV secretory pathway, TrbL components
------------------------------------------|||||-||||-|||----------  1 [T] COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific
------------------------------------------|||||-||--|--|---|||||--  1 [T] COG3852 Signal transduction histidine kinase, nitrogen specific
--------------------------|---||--||-------------|-----|---||-|---  1 [S] COG3865 Uncharacterized protein conserved in bacteria
---------------------------------------------||--------|---|||||--  1 [S] COG3892 Uncharacterized protein conserved in bacteria
-------------------------------------------------------|||||||||--  1 [L] COG3893 Inactivated superfamily I helicase
------------------|-----------------------|||||--|-----|---|||----  1 [R] COG3895 Predicted periplasmic protein
-------------------------------------------------|---|||----||----  1 [K] COG3901 Regulator of nitric oxide reductase transcription
-------------------------------------------------|-----|---|--|---  1 [S] COG3913 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|---|---|--  1 [Q] COG3917 2-hydroxychromene-2-carboxylate isomerase
-------------------------------------------------|--|--|---|||----  1 [U] COG3946 Type IV secretory pathway, VirJ component
----------------------------------------------|--|--|--|----------  1 [R] COG3948 Phage-related baseplate assembly protein
------------------------|-----------------||||||||-----|----------  1 [MNO] COG3951 Rod binding protein
------------------------------------------|||-|--|-----|----|-|---  1 [R] COG3960 Glyoxylate carboligase
--------------------------|--------|||-------||--------|---|||||--  1 [E] COG3962 Acetolactate synthase
-------------------------------||--|------|||-|--|-----|----------  1 [R] COG3969 Predicted phosphoadenosine phosphosulfate sulfotransferase
-----------|------||---------------------------------|||-------|-|  1 [R] COG3975 Predicted protease with the C-terminal PDZ domain
--|----------------|-------------|--------|||-|--------|----------  1 [V] COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
----------------------------------------------------|--|----|-|---  1 [G] COG4101 Predicted mannose-6-phosphate isomerase
-------------------------------------------------------|---|--||--  1 [S] COG4102 Uncharacterized protein conserved in bacteria
----------------|-------------------------||||||||||||||||||||||||  1 [R] COG4105 DNA uptake lipoprotein
------------------||-|----|---||||||------||||||||||||||---|||||--  1 [J] COG4108 Peptide chain release factor RF-3
-------------------|----------------------|||-|--|-----|-----||---  1 [C] COG4117 Thiosulfate reductase cytochrome B subunit (membrane anchoring protein)
--------------------|-----|-----||--------------||-----|---||||-||  1 [R] COG4120 ABC-type uncharacterized transport system, permease component
||--------------|-||-|---|----------------|||||-||||---|--|||--|--  1 [S] COG4121 Uncharacterized conserved protein
---------------------------------------------||--|-----|---||-----  1 [S] COG4125 Predicted membrane protein
----------------------------------------------|--------|---||-|---  1 [G] COG4130 Predicted sugar epimerase
------------------------------------------|||||-||-|||||----------  1 [R] COG4137 ABC-type uncharacterized transport system, permease component
--------|-------|--|-|----|---------||----|||||-||--|--|----------  1 [R] COG4147 Predicted symporter
--|---------|---|-||------|||-----||||----|||||-||||---|||||||||--  1 [P] COG4149 ABC-type molybdate transport system, permease component
-----------------|--|-|||||||-||-||||-||--|||||-||||---|||-||||---  1 [E] COG4166 ABC-type oligopeptide transport system, periplasmic component
--------------------|---------------------|||||-||-----|---||||---  1 [R] COG4172 ABC-type uncharacterized transport system, duplicated ATPase component
------------------------------------------|||||-||-----|||-||||---  1 [R] COG4174 ABC-type uncharacterized transport system, permease component
--|----------------------|-----||--||-----|||||--|-----|---||||---  1 [E] COG4175 ABC-type proline/glycine betaine transport system, ATPase component
--|----------------------|-----||--||-----|||||--|-----|---||||---  1 [E] COG4176 ABC-type proline/glycine betaine transport system, permease component
-------------|----||-------|||------------|||-----||-|-|---||||---  1 [R] COG4178 ABC-type uncharacterized transport system, permease and ATPase components
------------------------------------------|||||-||-----|---||-||--  1 [Q] COG4181 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component
------------------||-----------------|-----------|-----|---|---|--  1 [R] COG4188 Predicted dienelactone hydrolase
------------------------------------------|||||-||-----|-----|-|--  1 [H] COG4206 Outer membrane cobalamin receptor protein
------------------||-------||--------|----|||||-||--||||---|||||--  1 [P] COG4208 ABC-type sulfate transport system, permease component
-------------------------------------|-|--||||----|----|---||||---  1 [G] COG4213 ABC-type xylose transport system, periplasmic component
-------------------------------------|-|--||||----|----|---||||---  1 [G] COG4214 ABC-type xylose transport system, permease component
-------------------|-|---------------------||-------|--|----|----|  1 [S] COG4226 Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters
------------------------------------------|||||--|-|-|||---|||||--  1 [C] COG4230 Delta 1-pyrroline-5-carboxylate dehydrogenase
----------------------||------------------|||||-||||||||--|----|--  1 [OC] COG4232 Thiol:disulfide interchange protein
-------------------------|----------------|||||-||-----|||-||||---  1 [R] COG4239 ABC-type uncharacterized transport system, permease component
------------------||-|---------------------------|-----|----|--|--  1 [T] COG4252 Predicted transmembrane sensor domain
-------------------------------------------------|-----|----|--|--  1 [S] COG4254 Uncharacterized protein conserved in bacteria
----------------------------------------------------||||----------  1 [S] COG4255 Uncharacterized protein conserved in bacteria
------------------------------------------|||-|--------|----|-|---  1 [P] COG4256 Hemin uptake protein
---------------------------------------------|---|---|||----------  1 [S] COG4259 Uncharacterized protein conserved in bacteria
-------------------------------|----||-----------------|----------  1 [S] COG4260 Putative virion core protein (lumpy skin disease virus)
-------------------------------------------------|-----|----||----  1 [C] COG4263 Nitrous oxide reductase
-------------||----------------------------------|-----|----|-----  1 [F] COG4266 Allantoicase
-----------------|--|---------|------------------|-----|----------  1 [S] COG4267 Predicted membrane protein
---------------------|--------------------|||||--------|---||-----  1 [S] COG4269 Predicted membrane protein
--|------------------------------------|------------|--|-------|--  1 [K] COG4271 Predicted nucleotide-binding protein containing TIR -like domain
--|---|------------------------------------------|-----|----------  1 [S] COG4273 Uncharacterized conserved protein
--------|-|--------------------------------------------|----|-|---  1 [S] COG4274 Uncharacterized conserved protein
-----------|-------|-----------------------------|-----|----------  1 [S] COG4278 Uncharacterized conserved protein
-------------||------|---------------------------------|----------  1 [I] COG4281 Acyl-CoA-binding protein
-----------------|----------------------------|-----|--|----------  1 [R] COG4287 PhoPQ-activated pathogenicity-related protein
---------------------|----|-------------------------|--|----------  1 [F] COG4290 Guanyl-specific ribonuclease Sa
---------------------|---------------------------------|---||||---  1 [S] COG4291 Predicted membrane protein
---------------------|------------||-------------------|---||-----  1 [S] COG4292 Predicted membrane protein
--------------|---||-------||--------------------------|----------  1 [S] COG4301 Uncharacterized conserved protein
--------------------|---------|----|------|||-|--|-----|----------  1 [E] COG4302 Ethanolamine ammonia-lyase, small subunit
--------------------|---------|----|------|||-|--|-----|----------  1 [E] COG4303 Ethanolamine ammonia-lyase, large subunit
------------------------------------|---------------|--|----------  1 [G] COG4305 Endoglucanase C-terminal domain/subunit and related proteins
------------------------------|---------------------|--|----------  1 [S] COG4306 Uncharacterized protein conserved in bacteria
---------------------------||--------------------------|---|--|---  1 [S] COG4307 Uncharacterized protein conserved in bacteria
-----------|------------------|------------------------|---|||----  1 [S] COG4309 Uncharacterized conserved protein
-------------------------------------------------|-----|---||-|---  1 [S] COG4312 Uncharacterized protein conserved in bacteria
-------------------------------------------------|---|||----||----  1 [C] COG4314 Predicted lipoprotein involved in nitrous oxide reduction
-------------------------------------------------|-----|---||-----  1 [S] COG4315 Uncharacterized protein conserved in bacteria
-------------------------------------|-----------|-----|---||-----  1 [S] COG4317 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|---|--|---  1 [S] COG4318 Uncharacterized protein conserved in bacteria
----------------------------------------------------|--|------|---  1 [S] COG4320 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|---||||---  1 [R] COG4321 Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis
----------------------------------------------------|--|-------|--  1 [S] COG4322 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|-------|--  1 [S] COG4323 Predicted membrane protein
-------------------------------------------------|-----|------|---  1 [R] COG4324 Predicted aminopeptidase
-------------------|-----------------|----------|------|----------  1 [S] COG4327 Predicted membrane protein
-------------------|-----------------------------|-----|------|---  1 [R] COG4341 Predicted HD phosphohydrolase
---------------------------------|--|------------------|----------  1 [S] COG4377 Predicted membrane protein
---------------------------------------------|---|---|||----------  1 [S] COG4380 Uncharacterized protein conserved in bacteria
----------------------------------------------|--|--|--|---|------  1 [R] COG4385 Bacteriophage P2-related tail formation protein
---------------------------------------------------|-|||----------  1 [L] COG4389 Site-specific recombinase
---------------------------------------------------|-|||----------  1 [S] COG4390 Uncharacterized protein conserved in bacteria
----------------------------------------------------||||---|||-|-|  1 [S] COG4391 Uncharacterized protein conserved in bacteria
--------------------|----------------------------|----||----------  1 [S] COG4394 Uncharacterized protein conserved in bacteria
------------------------------------------------||-----|---|||||||  1 [S] COG4395 Uncharacterized protein conserved in bacteria
---------------------------||--------------||-|-|-|-|--|----|-----  1 [S] COG4453 Uncharacterized protein conserved in bacteria
-------------------------------------------------------|---||||-||  1 [M] COG4520 Surface antigen
------------------------------------------||||||||||||||----------  1 [P] COG4535 Putative Mg2+ and Co2+ transporter CorC
----------------------------------|-------|||||-||||---|----||||||  1 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB
-------------||----------------------------------|-----|----------  1 [S] COG4539 Predicted membrane protein
---------------------------------------------||--|--|--|----------  1 [R] COG4540 Phage P2 baseplate assembly protein gpV
-------------------------------------------------------|---||||---  1 [S] COG4541 Predicted membrane protein
-------------------|-----------------------------|-----|------|---  1 [R] COG4551 Predicted protein tyrosine phosphatase
-------------------------------------------------------|---||-||||  1 [I] COG4553 Poly-beta-hydroxyalkanoate depolymerase
------------------------------------------------|------|---|-|----  1 [T] COG4564 Signal transduction histidine kinase
----------------------------------------------|--|-|---|---|||||--  1 [T] COG4566 Response regulator
-------------------------------------------------|--|--|---|||||--  1 [TK] COG4567 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
---------------------------||-------------|||----------|----------  1 [Q] COG4569 Acetaldehyde dehydrogenase (acetylating)
------------------------------------------|||||--------|---||-|---  1 [G] COG4573 Predicted tagatose 6-phosphate kinase
------------------------------------------|||||--|-|---|----------  1 [S] COG4575 Uncharacterized conserved protein
------------------------------------------|||||--|-----|----------  1 [T] COG4579 Isocitrate dehydrogenase kinase/phosphatase
------------------------------------------|||||-|------|----------  1 [G] COG4580 Maltoporin (phage lambda and maltose receptor)
------------------------------------------|||||-|------|----------  1 [S] COG4582 Uncharacterized protein conserved in bacteria
--|-------------|---||--||----|-----------||||||||||||||||||||||||  1 [M] COG4591 ABC-type transport system, involved in lipoprotein release, permease component
---|--|||-|-|----|-|-|--||----||||-||-||||-------|-----|---||||---  1 [R] COG4603 ABC-type uncharacterized transport system, permease component
------------------------------------------|||-|--|-----|--|-------  1 [QP] COG4615 ABC-type siderophore export system, fused ATPase and permease components
----------------------------------|-------|||-|--------|----------  1 [R] COG4619 ABC-type uncharacterized transport system, ATPase component
--------------------|----------------------------|--|--|---|--|---  1 [S] COG4625 Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain
---------------------|---------------------------|-----|---||||---  1 [F] COG4630 Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A
---------------------|---------------------------|-----|---|||||--  1 [F] COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B
------------------------------------------|||-|--|-----|----------  1 [KT] COG4650 Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain
------------------------------------------|||||-||--|--|----|||---  1 [P] COG4651 Kef-type K+ transport system, predicted NAD-binding component
---------------------------||--------------||----------|---|--||--  1 [R] COG4653 Predicted phage phi-C31 gp36 major capsid-like protein
-------------------------------------------------|-----|---||-|---  1 [S] COG4655 Predicted membrane protein
|---------|-------------------------------------|------|--|-------  1 [H] COG4662 ABC-type tungstate transport system, periplasmic component
---------------------|--------||-|||||--|-||||||||||---|----------  1 [G] COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain
----------------------||-------------------||||--|-----|------|---  1 [U] COG4669 Type III secretory pathway, lipoprotein EscJ
---||-----|-|-------|-------------||-|----|||-|--------|----|||---  1 [I] COG4670 Acyl CoA:acetate/3-ketoacid CoA transferase
-------------------------------------------||||--|-----|----------  1 [S] COG4672 Phage-related protein
------------------||-|----|----------|-------|---|-----|---||-|---  1 [R] COG4674 Uncharacterized ABC-type transport system, ATPase component
------------------------------|-----------|||||--------|----------  1 [G] COG4677 Pectin methylesterase
------------------||-----------------------||----------|----------  1 [G] COG4678 Muramidase (phage lambda lysozyme)
------------------------------------------|||||--|-----|----------  1 [S] COG4681 Uncharacterized protein conserved in bacteria
------------------------------------|-----|||||--------|----------  1 [S] COG4682 Predicted membrane protein
------------------------------------------|||----|-----|----------  1 [S] COG4685 Uncharacterized protein conserved in bacteria
------------------------------|------------------------|------|---  1 [Q] COG4689 Acetoacetate decarboxylase
---------------------------------------------|---|-----|----------  1 [Q] COG4693 Oxidoreductase (NAD-binding), involved in siderophore biosynthesis
----------------------------------------------------|--|||--------  1 [S] COG4694 Uncharacterized protein conserved in bacteria
------------------------------|||---------|||----------|---|-|||--  1 [S] COG4695 Phage-related protein
-------------------------------------------||----------|-------|--  1 [S] COG4700 Uncharacterized protein conserved in bacteria containing a divergent form of TPR repeats
-------------------|-----------------------------------|-------|--  1 [S] COG4704 Uncharacterized protein conserved in bacteria
----------------------------------------------|----|---|----------  1 [S] COG4714 Uncharacterized membrane-anchored protein conserved in bacteria
-------------------------------------------||||--|-----|----------  1 [S] COG4718 Phage-related protein
-------------------------------------------||||--|-----|----------  1 [S] COG4723 Phage-related protein, tail component
----------------------------------------------|-----|--|----------  1 [S] COG4727 Uncharacterized protein conserved in bacteria
------------------------------|------------------|-----|----------  1 [S] COG4728 Uncharacterized protein conserved in bacteria
-------------------------------------------||||--|-----|----------  1 [S] COG4733 Phage-related protein, tail component
------------------------------------------------|-----|||||-|-||--  1 [O] COG4736 Cbb3-type cytochrome oxidase, subunit 3
-------------------|-----------------------||-|------|||----|-----  1 [S] COG4737 Uncharacterized protein conserved in bacteria
----||----||----------------------------------------|--|----------  1 [S] COG4754 Uncharacterized conserved protein
--------------------------|----------------------|-----|-----|----  1 [R] COG4757 Predicted alpha/beta hydrolase
---|----------------------||||-------------------|-----|---|||||||  1 [I] COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit
-------------||-||||||||||----------------||||||||||||||||||||||||  1 [M] COG4775 Outer membrane protein/protective antigen OMA87
-------------------|-----------------------------------|---||||---  1 [S] COG4782 Uncharacterized protein conserved in bacteria
----------------|-||----------------------|||||-||--|--|-----|||--  1 [R] COG4783 Putative Zn-dependent protease, contains TPR repeats
----------------||------||----|----|||----||||||||-----|||||||||--  1 [N] COG4786 Flagellar basal body rod protein
------------------------------------------||||||||-----|----------  1 [N] COG4787 Flagellar basal body rod protein
----------------------||-------------------||||--|-----|------|---  1 [U] COG4789 Type III secretory pathway, component EscV
-------------------------------------------||||--|-----|------|---  1 [U] COG4790 Type III secretory pathway, component EscR
----------------------||-------------------||||--|-----|------|---  1 [U] COG4791 Type III secretory pathway, component EscT
----------------------||-------------------||||--|-----|------|---  1 [U] COG4794 Type III secretory pathway, component EscS
------------------------------------------|||||-|||||--|-------|--  1 [U] COG4795 Type II secretory pathway, component PulJ
---|--|||--|-||--|--||----||||------||-----------|-----|---|||||||  1 [I] COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
--|-----------------|---------------------|||-|--------|---------|  1 [S] COG4804 Uncharacterized conserved protein
--------------------------|||--------------------------|----------  1 [S] COG4849 Uncharacterized protein conserved in bacteria
--------------------------|||--------------------------|----------  1 [S] COG4861 Uncharacterized protein conserved in bacteria
--------------------|---------------------------|------|----------  1 [S] COG4874 Uncharacterized protein conserved in bacteria containing a pentein-type domain
----------------------------------------------------|--|-----|----  1 [S] COG4875 Uncharacterized protein conserved in bacteria with a cystatin-like fold
------------------|------------------------------------|-----|----  1 [S] COG4916 Uncharacterized protein containing a TIR (Toll-Interleukin 1-resistance) domain
--------------------|------------|---------------------|---|------  1 [S] COG4922 Uncharacterized protein conserved in bacteria
--|-------------------------------------------------|--|----------  1 [S] COG4925 Uncharacterized conserved protein
-------------------------------------------------|-----|----|-||--  1 [K] COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain
--------------------------|---------------|||||--------|---||-----  1 [S] COG4950 Uncharacterized protein conserved in bacteria
-------------------------------------------------------|---|--|---  1 [S] COG4954 Uncharacterized protein conserved in bacteria
----------------------------------------------------|--|---|--|---  1 [OU] COG4959 Type IV secretory pathway, protease TraF
------------------||-|--------------------------||--||||----------  1 [NU] COG4972 Tfp pilus assembly protein, ATPase PilM
------------------------------------------|||||-||||||||----------  1 [L] COG4973 Site-specific recombinase XerC
----||----||----------------------------------------|--|----------  1 [P] COG4986 ABC-type anion transport system, duplicated permease component
------------------------------|----|-------------------|----------  1 [S] COG4994 Uncharacterized protein conserved in bacteria
----------------|------------------------------------|||---|||||||  1 [T] COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation
-------------------------------------------------------|---|---|--  1 [T] COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain
----------------------------------------------|--|--|--|----------  1 [R] COG5004 P2-like prophage tail protein X
---------------------|----|---------------|||||-||-----|------||--  1 [R] COG5006 Predicted permease, DMT superfamily
------------------------------------------||||||||||||||----------  1 [K] COG5007 Predicted transcriptional regulator, BolA superfamily
------------------------------------------------||--||||----------  1 [NU] COG5008 Tfp pilus assembly protein, ATPase PilU
----------------|-------||----------------|||||-||||||||---|||||||  1 [M] COG5009 Membrane carboxypeptidase/penicillin-binding protein
---------------------------------------------|---|-|---|---||-||--  1 [U] COG5010 Flp pilus assembly protein TadD, contains TPR repeats
----------|-|-------------|||-----|-|-----|||-|--|-----|-----|----  1 [C] COG5013 Nitrate reductase alpha subunit
-------------||------------------------------|---------|---|||||||  1 [O] COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components
-------------------------------------------------------|---|--||--  1 [S] COG5267 Uncharacterized protein conserved in bacteria
----------------------------------------------------|--|---|--|---  1 [NU] COG5268 Type IV secretory pathway, TrbD component
-------------------|-|---------------|-----------------|---|--||--  1 [T] COG5278 Predicted periplasmic ligand-binding sensor domain
-------------|-----|-------||--------------------------|----|-|---  1 [Q] COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin
--|-----------------|----------------|-----||||---||||||----|||---  1 [UW] COG5295 Autotransporter adhesin
---------------------------||-----------------------|--|----------  1 [G] COG5297 Cellobiohydrolase A (1,4-beta-cellobiosidase A)
-----------------------------------||------------------|----------  1 [S] COG5298 Uncharacterized protein conserved in bacteria
----------------------------------------------|--|-----|----------  1 [R] COG5301 Phage-related tail fibre protein
----------------------------------------------------|--|---|--|---  1 [U] COG5314 Conjugal transfer/entry exclusion protein
-------------------------------------------------------|---|||||--  1 [S] COG5319 Uncharacterized protein conserved in bacteria
------------------||-|---------------------------------|----------  1 [R] COG5322 Predicted dehydrogenase
-------------------------------------------------------|---||-|---  1 [S] COG5343 Uncharacterized protein conserved in bacteria
--|--------------------------------|-------------------|----|-||--  1 [S] COG5361 Uncharacterized conserved protein
---------------------------------------------|---|-----|---||-|---  1 [S] COG5373 Predicted membrane protein
------------------------------------------|||||--|-----|----------  1 [S] COG5393 Predicted membrane protein
-------------------------------------------------------|---||-||--  1 [S] COG5394 Uncharacterized protein conserved in bacteria
--------------------------||||-----|||---------------|||----------  1 [S] COG5416 Uncharacterized integral membrane protein
---------------------------------------------|---------|------||--  1 [S] COG5419 Uncharacterized conserved protein
-------------------------------------------------------|---|||||--  1 [S] COG5429 Uncharacterized secreted protein
------------------------------------------|||-|--------|---|||||--  1 [S] COG5455 Predicted integral membrane protein
--|----------------------------------------------------|---||||---  1 [S] COG5470 Uncharacterized conserved protein
---------------------------------------------|---------|--|-------  1 [S] COG5472 Predicted small integral membrane protein
-------------------------------------------------------|---||||---  1 [S] COG5476 Uncharacterized conserved protein
-------------------------------------------------------|---||-|---  1 [S] COG5477 Predicted small integral membrane protein
-------------------|-----------------------------|-----|---||-|---  1 [R] COG5485 Predicted ester cyclase
-------------------------------------------------------|----|-|---  1 [S] COG5486 Predicted metal-binding integral membrane protein
-------------------------------------------|-||--|-----|---||||---  1 [S] COG5487 Small integral membrane protein
-------------------------------------------------------|---|||||--  1 [S] COG5488 Integral membrane protein
-------------------------------------------------------|---||-||--  1 [S] COG5489 Uncharacterized conserved protein
-----------------|---------|||-------------------------|----------  1 [S] COG5495 Uncharacterized conserved protein
----------------|--------------------------------------|----|-----  1 [S] COG5501 Predicted secreted protein
-------------------------------------------||-|-----|--|----------  1 [R] COG5511 Bacteriophage capsid protein
-------------------------------------------------------|-----||---  1 [S] COG5514 Uncharacterized conserved protein
-------------------------------------------------------|----|-|---  1 [R] COG5516 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding
--------------------------|---------------|||----|-----|----------  1 [Q] COG5517 Small subunit of phenylpropionate dioxygenase
-----------------------------------||---------|--------|----------  1 [R] COG5518 Bacteriophage capsid portal protein
-------------------|---------------|------|||-|-----|--|----------  1 [R] COG5525 Bacteriophage tail assembly protein
---------------------|---------------------------------|------|---  1 [L] COG5534 Plasmid replication initiator protein
------------------------------------------|||||--|-----|----------  1 [R] COG5544 Predicted periplasmic lipoprotein
------------------------------------------|||----------|---||-----  1 [S] COG5569 Uncharacterized conserved protein
-------------------------------------------------------|----|--|--  1 [S] COG5572 Predicted integral membrane protein
------------|------|-----------------------------------|----|-----  1 [R] COG5573 Predicted nucleic-acid-binding protein, contains PIN domain
-------------------------------------------------------|----|-|---  1 [S] COG5588 Uncharacterized conserved protein
------------------------------------------------|------|-----|----  1 [S] COG5591 Uncharacterized conserved protein
-------------------------------------------------------|----|-|---  1 [S] COG5605 Predicted small integral membrane protein
--|--------|------||-----------------------------|-----|----|-----  1 [S] COG5607 Uncharacterized conserved protein
------------------------------|------------||----------|---|------  1 [R] COG5614 Bacteriophage head-tail adaptor
-------------------------------------------------------|-----||---  1 [K] COG5631 Predicted transcription regulator, contains HTH domain (MarR family)
-------------------|----------------|------------------|----------  1 [S] COG5634 Uncharacterized conserved protein
-------------------------------------------------------|------||--  1 [S] COG5639 Uncharacterized conserved small protein
-------------------------------------------------------|----|-|---  1 [S] COG5649 Uncharacterized conserved protein
--||-------------|---|--------|----|-|-----------------|----------  1 [S] COG5652 Predicted integral membrane protein