(Eco) Escherichia coli K12 Functional categories Fun All J A K L B D Y V T M N Z W U O C G E F H I P Q R S COGs 2,131 140 2 93 117 -  30 -  25 65 132 56 -  -  60 93 163 151 200 70 124 57 146 38 252 274 proteins 3,762 182 2 329 236 -  36 -  50 210 246 115 -  -  136 140 311 426 446 92 152 108 284 81 517 326 Distribution of COGs by number of proteins proteins 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 18 19 20 25 27 48 61 COGs 1513 327 118 64 34 22 6 10 7 5 4 7 2 1 3 1 1 1 1 1 1 1 1

Co-ocurrences in sister taxa 0 1 2 3 4 5 order Enterobacteriales 28 20 90 298 1142 553

++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
||||||||||||||||||||||||||||||||||||||-||||||||||||||||||||||||||| 61 [GEPR] COG0477 Permeases of the major facilitator superfamily
||------||------|-||||----||||||||||||----|||||-||||||||--||||||-- 48 [K] COG0583 Transcriptional regulator
-----------------||||-----|||-||-|||||----|||||-||||||||--||||||-- 27 [K] COG2207 AraC-type DNA-binding domain-containing proteins
------------------------------------------|||||--|--|------------- 25 [NU] COG3539 P pilus assembly protein, pilin FimA
|-||----|----||-||||||||-|||||||||||||----|||||-|||||||||||||||||| 20 [T] COG0642 Signal transduction histidine kinase
----------------||||-|--|-|||||---||||----|||||-||--|--|---|||||-- 19 [T] COG2199 FOG: GGDEF domain
--|-||--|----||---||||----|||--|||||-|||--|||||-|||--|||---|||||-- 18 [L] COG2801 Transposase and inactivated derivatives
--|||||||-||||||||||||||--||||||||||||----|||||||||||||||||||||||| 17 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
----------------||||||||--||||||||||||----|||||-|||||||||||||||||| 15 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
-----------------|--||----|||-||||||||-|--|||||-|||||--|---|||||-- 15 [K] COG1609 Transcriptional regulators
----------------|-||-|---||||||----|||----|||||-||--|--|---||||||| 15 [T] COG2200 FOG: EAL domain
-----|--------------||----|||--|||||-|----|||||-|||----|---|||||-- 14 [L] COG2963 Transposase and inactivated derivatives
|||||||||||||||||||||||||-||||||||||||----|||||||||||||||||||||||| 13 [QR] COG0500 SAM-dependent methyltransferases
||||||--||||||||--|||-||--|||||||||||||||||||||-|||||--|---||||||| 13 [E] COG0531 Amino acid transporters
|-||||--|-|||||||||||||||-||||||||||||----|||||||||||||||||||||||| 12 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
|||||||||--||---||||||||--||||||||||||||--|||||-|||||||||||||||||| 12 [L] COG0582 Integrase
||||||---||||||-|-||||----|||||||||||||---|||||-||-|-|||||||||||-| 12 [C] COG1012 NAD-dependent aldehyde dehydrogenases
--|||||||--||||--|-|-|-----||-||||||||--|-|||||-|||-||||---||-||-- 12 [ER] COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
|-||---||--|----||||||----|||||||||||||---|||||-||||||||--||||||-- 12 [K] COG1309 Transcriptional regulator
----------------||--||----|---||||||||----|||||-||||-|||---||||--- 12 [KG] COG1349 Transcriptional regulators of sugar metabolism
------------------||-|----|||-||||||||----|||||-||||||||---|||||-- 12 [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
||-||||||||||---|-||-|----|||-------||----|||||-||||---|||||||||-- 11 [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing
--||||---------------------||-------------|-----|----|||---||-|--- 11 [L] COG3039 Transposase and inactivated derivatives, IS5 family
------------------|--|--------------------|||||--|--|--|---||-|--| 11 [NU] COG3121 P pilus assembly protein, chaperone PapD
------------------|-----------------------|||||--|--|--|---|--|--| 11 [NU] COG3188 P pilus assembly protein, porin PapC
|||||||||-||||||||||||||--|||||||||||||---|||||-||||||||||||||||-| 10 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
|-|||||||-|||||||||||||||-|||-||-|||||----|||||||||||||||||||||||| 10 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily
--------------------|-|||||---||||||||-||||||||-||||-|||---|||||-- 10 [GT] COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)
---------------------|----|||||----|||----|||||-||||-|||---|||||-- 10 [K] COG2186 Transcriptional regulators
------------------------------------------|||||---||-||----||||--- 10 [MU] COG3468 Type V secretory pathway, adhesin AidA
--|-||----|--||--|||-|----|||-||||||||-|--|||||-||-----|---||-||--  9 [G] COG0366 Glycosidases
|||||||||||||||--|||-|----||||||||||||----|||||-|||||--|---|||||--  9 [G] COG0524 Sugar kinases, ribokinase family
--|-----|-|-|----||||||||-||||||||||||----|||||-||||-|||||||||||||  9 [ET] COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain
-----------------|--|---|||----|----||-|--|||||-||||---|---|||||--  9 [G] COG1129 ABC-type sugar transport system, ATPase component
---|------------||--||----|||||||-||||----||||||||||||||---|||||||  9 [K] COG1278 Cold shock proteins
---------||-------||-|----||||||--||||----|||||-||-----|---|||||--  9 [K] COG2771 DNA-binding HTH domain-containing proteins
------------------------------------------|||||||-||-|||----------  9 [M] COG3203 Outer membrane protein (porin)
--||---||-|||---|-------------------------|||||-||||---|--|-|-|---  8 [C] COG0437 Fe-S-cluster-containing hydrogenase components 1
-------------||---||------------||--------|||||-||||||||---|||||||  8 [O] COG0625 Glutathione S-transferase
-------------|||------||--|---------------|||||-||||-||-|||-------  8 [E] COG0814 Amino acid permeases
----------------||||||--|||---|-||||||----|||||-||||||||||||||||||  8 [M] COG0845 Membrane-fusion protein
-----------------|--|-----|--|-|----||----|||||-||||---|---|||||--  8 [G] COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components
--------------------|----||---||||||||-|||||||||||-|---|-------|--  8 [G] COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific
--------------------|----||---||||||||||||||||||||-|---|-------|--  8 [G] COG1264 Phosphotransferase system IIB components
---|------------||---|----|||-------||----|||||-||||---|--||||||--  8 [K] COG1414 Transcriptional regulator
--|--------------|--|---|-|--|||----||----|||||-||||---|---|||||--  8 [G] COG1879 ABC-type sugar transport system, periplasmic component
--|---------------------------|----||-----|||||--|-----|------|---  8 [M] COG3209 Rhs family protein
|-||--|||----|||-|||-|--||-||-|----|||----|||||-|||||--|||||||||--  7 [T] COG0784 FOG: CheY-like receiver
--------------------------|||||||-||||----|||||--|---------|-|----  7 [E] COG1113 Gamma-aminobutyrate permease and related permeases
|||---||||-------|||----------------------|||||-------------------  7 [C] COG1142 Fe-S-cluster-containing hydrogenase components 2
----------------|-----------------|-|-----|||||-|||--|||---|||||||  7 [V] COG1566 Multidrug resistance efflux pump
---|||--|-|-|---||||||---|||||||||||||-|--|||||-|-||-------|||||--  7 [KG] COG1940 Transcriptional regulator/sugar kinase
--|-----------------|-----|---|-|-|-||----|||||-||||-|||----------  7 [GE] COG2610 H+/gluconate symporter and related permeases
||||-||||||-|||-||-||------||||-||-|||-||-|||||-|||||--|||--||||||  6 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
--||||--|-|||||-|-||||----|||||-----||----|||||-||||||||||||||||--  6 [C] COG0277 FAD/FMN-containing dehydrogenases
||||||||||||||||||||||---|||||||||||||----|||||-||||||||||||||||||  6 [M] COG0438 Glycosyltransferase
|-||||||||||||||-||||||||||||||||||||||||||||||||-||-|||---||-|---  6 [R] COG0561 Predicted hydrolases of the HAD superfamily
|||||||||||||-|-|-||-|----||||-|||||||----|||||-||||-|||---|||||||  6 [T] COG0589 Universal stress protein UspA and related nucleotide-binding proteins
|-||||||-|||-||-||||-|----|---||||||||----|||||-||-|---|||||||||--  6 [R] COG0673 Predicted dehydrogenases and related proteins
--|-------------||||||---|----|---|-||----|||||-||||||||||||||||||  6 [V] COG0841 Cation/multidrug efflux pump
----------------|-|||---------------------|||||-|||||||||||---||--  6 [M] COG0859 ADP-heptose:LPS heptosyltransferase
---|||--|-|||||-|--|||----|||||-|||-||----|||||-||--|--|---|||||||  6 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase
--------|---|||--|||----|||||-||-|||||----|||||--|||---|---||||---  6 [G] COG1070 Sugar (pentulose and hexulose) kinases
------------------|--|------------|||-----|||||-||||||||--|||||---  6 [S] COG1289 Predicted membrane protein
|-|-------|-----||-|||--|-|||-||||||||----|||||-||||||||---|||||||  6 [K] COG1396 Predicted transcriptional regulators
--------------------||---||---||||||||-||||||||-||||---|----------  6 [G] COG1445 Phosphotransferase system fructose-specific component IIB
--|--------|----|-|-----------------------||||-----|--------------  6 [L] COG1662 Transposase and inactivated derivatives, IS1 family
-------------------|-|----|||-||||||||||--|||||-||-----|---|||||--  6 [K] COG2188 Transcriptional regulators
------------------------------------------|||||-|||||||-||||||--||  6 [R] COG2194 Predicted membrane-associated, metal-dependent hydrolase
|-||----|-----|-||||-|||-||||||----|||----|||||-||--|--|--||||||--  6 [T] COG2202 FOG: PAS/PAC domain
------------------|||---------||----|-----|||||----------------|--  6 [G] COG2211 Na+/melibiose symporter and related transporters
-------|------|--|--||----|---||||||||----|||||-||||-|||---|||----  6 [F] COG2233 Xanthine/uracil permeases
--||--||---|------|-----------|-----------|||||--------|----------  6 [L] COG3677 Transposase and inactivated derivatives
---|||--||-||----|||||----||||||--||||----|||||--|-----|---|||||--  6 [MR] COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily
-------------------|------------|---------|||---------------|-----  6 [L] COG5433 Transposase
|||-||-||||||||-||||-|----||||||-|||||----||||||||||||||--||||||--  5 [EH] COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]
||||---|-||--||--|||-|||--||||||||||||----|||-|-||-|-|||--||||||-|  5 [R] COG0110 Acetyltransferase (isoleucine patch superfamily)
||||||||||||||||--|-||---||||||||-||||----|||||-|||----|||-|||||||  5 [I] COG0183 Acetyl-CoA acetyltransferase
-------------|---|--------|---||-||-||-||-||||||||-|---|---|||||--  5 [G] COG0246 Mannitol-1-phosphate/altronate dehydrogenases
---|--||--|||||-||||||----||||||||||||----||||||||||||||||||||||--  5 [J] COG0251 Putative translation initiation inhibitor, yjgF family
|-||||--|-|||||---||-|||--||||-||-||||----|||||-||||||||--||||||||  5 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II
||||||||||||-||-||||||---|||||||-|||||----|||||-||||||||||||||||--  5 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases
||||||||||||||||||||||---||||||||||||||||||||||-||||||||||||||||||  5 [M] COG0463 Glycosyltransferases involved in cell wall biogenesis
||-|--||-||--||-|-|--|||--|---|||||-||----|||||-||||||||||||||----  5 [P] COG0471 Di- and tricarboxylate transporters
--|-||||--|-|||||||--|--|-||||||--||||----|||||-||--|--|--||||||||  5 [ER] COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
|||-||--|--|-||||-||||--|-||||||||||||||||||||||||||||||||-|||||||  5 [LKJ] COG0513 Superfamily II DNA and RNA helicases
----||-----|------||-|--||||||||--||||----|||||||||||||||||--|||--  5 [S] COG0586 Uncharacterized membrane-associated protein
--||||--|-|||||||-||||---|||||||-||||||||||||||-||||||||||||||||||  5 [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) 
--|||||||-|||---||||||||-||||||||||||||||||||||-||||---||||||||---  5 [EP] COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components
|-||||--|-||-||||-||||---|||||||||||||----|||||||||||||||||||-||||  5 [P] COG0607 Rhodanese-related sulfurtransferase
--|-|||---||-||--|||-|||--|||||||-||||-|--|||||-||||||||---|||||--  5 [R] COG0637 Predicted phosphatase/phosphohexomutase
---|||----|||||-||||||---|||||-|--||||----|||||-||--|--||--||-||--  5 [C] COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)
----------------||||----||----||||-|||----||||||||||||||||||||||||  5 [M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)
--|-----|-|-|----|||||||--|---||||||||----|||||-|||--|||||||||||||  5 [E] COG0765 ABC-type amino acid transport system, permease component
--|-----|-------|-||||----||||||||||||----|||||-||||||||||||||||||  5 [K] COG0789 Predicted transcriptional regulators
--||--|||--------|||-|--||----|----|||----|||||-||--|--||||||-||--  5 [NT] COG0840 Methyl-accepting chemotaxis protein
|-||||||||||||||-|||-|----||||||||||||----|||||-||-||--|||-|||||--  5 [V] COG0842 ABC-type multidrug transport system, permease component
---|---------||-----||----|||-----|-||----||||||||--||||---|||||--  5 [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1
--|||||||-|||---||||||||-||||||||||||||||||||||-||||---||-|||||---  5 [EP] COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components
|-|-||--|||||----||--|----|---------||----|||||-|||||--|--||||||--  5 [E] COG1280 Putative threonine efflux protein
--------------------||---||---||||||||-||||||||-|||----|----------  5 [G] COG1299 Phosphotransferase system, fructose-specific IIC component
----------------|-|||---------------------|||||-||||||||||||||||||  5 [MU] COG1538 Outer membrane protein
--------------------|||||||---||||||||||||||||||||||||||---|||||--  5 [G] COG1925 Phosphotransferase system, HPr-related proteins
-----||---|-------||-|----|||-|-||||||----|||||-||--|--|---|||||--  5 [L] COG1961 Site-specific recombinases, DNA invertase Pin homologs
------------------|||------||||--|||||----|||||-||||---|----|-----  5 [E] COG1982 Arginine/lysine/ornithine decarboxylases
-------------||---||----------------------|||||-||||----------|---  5 [T] COG2198 FOG: HPt domain
-|-|--||------|--|||||--|||---||||||||-|--|||||-||||-||||||-||-|--  5 [R] COG2252 Permeases
-----------------|--|-|||||||-||-||||-||--|||||-||||---|||-||||---  5 [E] COG4166 ABC-type oligopeptide transport system, periplasmic component
------------------||----------------------|||||------------------|  5 [S] COG5464 Uncharacterized conserved protein
|||----||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  4 [EG] COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase
-|--||-------||-||||-|||--|||||-||||||----||||||||||-|||||||||||--  4 [G] COG0176 Transaldolase
-------------||-||||-|--||||||||||||||||||||||||||||-||||||-||||--  4 [G] COG0191 Fructose/tagatose bisphosphate aldolase
||||||--|||||---|-||||----||||-|----||----|||||-||||-||||||||||---  4 [C] COG0247 Fe-S oxidoreductase
--|----------||-|-||-|----||||----|-||----||||||||||||||---|||||||  4 [S] COG0316 Uncharacterized conserved protein
|||||||||||||---|||||-||--||||||||||||----||||||||||||||||||||||||  4 [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase
|||||||||||||||-||||-|----|---|--|---|----|||||--||||--|||||||||--  4 [FR] COG0402 Cytosine deaminase and related metal-dependent hydrolases
|-||||-------|||||||||||||||||||||||||||||||||||||||||||||||||||||  4 [O] COG0443 Molecular chaperone
--|||||||-|||---||--||||-||---|||||||||||||||||-||||---||||||||---  4 [EP] COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
|||||||||--|-|||||||||||||----||||||||----|||||-||-|||||||||||||||  4 [R] COG0457 FOG: TPR repeat
-------------|||--||||||||||||||||||||-|--||||||||||||||||||||||||  4 [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains
|||||||||-||||||||||||||||||||||||||||||||||||||||||||||||||||||||  4 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins
-------------|||||||||||||||||||||||||||||||||||||||||||||||||||||  4 [J] COG0564 Pseudouridylate synthases, 23S RNA-specific
-||||||||-|||----|||||----|---|||||||||---|||||-||||---|||||||||--  4 [P] COG0609 ABC-type Fe3+-siderophore transport system, permease component
-|--|||||||||||-||--||-|--||||||||||||----||||||||||||||||||||||||  4 [E] COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases
||||--|||-------||||||--|||||-||||||||----||||||||||||||||||||||||  4 [R] COG0628 Predicted permease
|||||||||||||||-|||||-----|||||-----------|||-|--|--||||---|||||--  4 [C] COG0644 Dehydrogenases (flavoproteins)
-------------||---||-|----|||-----|-||----|||||-||-|||||---|||||||  4 [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
--|||||||-|||||-|-||-|||-|||||||||-|||----|||||-||||||||||||||||--  4 [E] COG0665 Glycine/D-amino acid oxidases (deaminating)
|||||||||||||-||||||||--|||||-||||||||----||||||||--||||||||||||||  4 [M] COG0668 Small-conductance mechanosensitive channel
||||--||-|-|-||||-||||--|-||||||||||||----|||||-|||||--|||-|||||||  4 [I] COG0671 Membrane-associated phospholipid phosphatase
|||-----||---||---|||---|-----||||-||-----|||||||||||--||||-------  4 [C] COG0716 Flavodoxins
--|||||||-|||---||||||||--|||||||-||||----|||||-||||---||||||||---  4 [E] COG0747 ABC-type dipeptide transport system, periplasmic component
----||----------||||||||||-|||||||||||||||||||||||||||||||||||||||  4 [L] COG0776 Bacterial nucleoid DNA-binding protein
|||||--||||||---||||||----||||||||||||----|||||-||||||||||||||||--  4 [C] COG0778 Nitroreductase
------------------||-|||--||||||---|||----|||||-||||||||||||||||--  4 [M] COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
|||------|-|----|--|||--------||||||||----|||||-||||-|||||||||----  4 [O] COG0826 Collagenase and related proteases
------------------||-|----|||-|---||||----||||||||||||||||||||||||  4 [P] COG0861 Membrane protein TerC, possibly involved in tellurium resistance
||||--||-|||-|||-|-|-|--|||||-||||||||----|||||-||-|-|||---|||||--  4 [R] COG1011 Predicted hydrolase (HAD superfamily)
--||---||---||||-|-|||||--|||-|||--|||----|||||-||-||--|---|||||--  4 [R] COG1073 Hydrolases of the alpha/beta superfamily
--------------------||||-||---||||||||-|||||||||||||||||------||--  4 [G] COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)
--|-----|-|-|----|||||||--|---||||||||----|||||-|||--|||||||||||||  4 [E] COG1126 ABC-type polar amino acid transport system, ATPase component
|||-|||||||||---||--|------||-||||||------|||||-||||---|----------  4 [O] COG1180 Pyruvate-formate lyase-activating enzyme
----------------||||||||||||||||||||||-|--||||||||||||||||||||||||  4 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases
||||||||||-|||--||||-|----|||-||---|||||--|||||-|||-||||||||||||||  4 [P] COG1226 Kef-type K+ transport systems, predicted NAD-binding component
||||||--|||||||-||||||||--||||-|||||||-|||||||||||||||||---|||||||  4 [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
--|||||||||||||-||-|-|--|||||-||||||||----|||||-||--||||--||||||--  4 [Q] COG1335 Amidases related to nicotinamidase
-----------------|||------|||||-----||----|||-|-||---|||---||||---  4 [S] COG1376 Uncharacterized protein conserved in bacteria
-------------------|||----|--||||||||||-|||||||-||||||||--||||||--  4 [P] COG1393 Arsenate reductase and related proteins, glutaredoxin family
|-|||||||--||||-||--|-----|---||-|||||----|||||-||-|---|---||||---  4 [C] COG1454 Alcohol dehydrogenase, class IV
----||--|-|--|||-||||-||--|---||||||||||--||||||||||||||||-|||||||  4 [I] COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes
----------------|-|||---------------------|||||-||||||||||||||||--  4 [P] COG1629 Outer membrane receptor proteins, mostly Fe transport
--------------------|-||||||||||||||||----|||||-||||||||---|||||||  4 [M] COG1686 D-alanyl-D-alanine carboxypeptidase
-----------------|--------|---||||||||-|--|||||-||||-|||---|||||--  4 [K] COG1737 Transcriptional regulators
--------------------||----||||||||||||----|||||-||||-|||||||||||--  4 [E] COG1760 L-serine deaminase
----|------|-----|--||----|||-|||-||||----|||||-||---|||---|||||--  4 [K] COG1802 Transcriptional regulators
|-------|-----------|---------||||||------|||||-|-||---|----------  4 [C] COG1882 Pyruvate-formate lyase
---|||--|-||||-----|||----|||||---|-||----|||||-||---|||---|||||--  4 [I] COG1960 Acyl-CoA dehydrogenases
--|-------------|||||---------||||||||----|||||-||||||||---||||--|  4 [L] COG2003 DNA repair proteins
--|||||||-||--|-|----|----|||--|||||||----|||||-||||---|||||||||--  4 [Q] COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism
--||---------------|-|-----|||||---|||----|||||-||---||---||||||--  4 [P] COG2076 Membrane transporters of cations and cationic drugs
|-|-||----|||---|-||-|-----||-||---|||----|||||-||||-|||-|-|||||--  4 [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
---------|---|------|---------|||||||-----|||||-||||--------------  4 [P] COG2116 Formate/nitrite family of transporters
----------------||||||||------||||||||----|||||-|||||--|--|---||--  4 [NU] COG2165 Type II secretory pathway, pseudopilin PulG
----------------|---|-||||-----------|----|||||-||-|||||||||||||||  4 [T] COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
||||||||||-|-----|-|||----|---||||||||----|||||-||||||||---|||||--  4 [R] COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
--|-----------|-----|---------|----||||---|||||-||||-||||||-|-||--  4 [R] COG2249 Putative NADPH-quinone reductase (modulator of drug activity B)
--------------------|---------|--|-----|--|||||-|-||----||--------  4 [G] COG2731 Beta-galactosidase, beta subunit
--------------------------|||--|--||||----|||||--||||--||||||-|---  4 [G] COG2814 Arabinose efflux permease
----------------|--||-||||-||-------------||||||||||||||||||||||||  4 [M] COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins
-------------|||----------|---||--|||-----|||||-|---|||--------|--  4 [E] COG3104 Dipeptide/tripeptide permease
--||-|-----|------||-|---------------|----|------------|----|-----  4 [L] COG3385 FOG: Transposase and inactivated derivatives
--||----|-|-|----|||||--|||---||||||-||||||||||-||||-|||--||||||--  4 [E] COG3842 ABC-type spermidine/putrescine transport systems, ATPase components
--|----------|||---|----------|-|--|------|||||--|-----|----------  4 [S] COG4886 Leucine-rich repeat (LRR) protein
|||||||||||||||||||||||||||||||||||||||||||||||-||||||||||||||||||  3 [E] COG0006 Xaa-Pro aminopeptidase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  3 [J] COG0008 Glutamyl- and glutaminyl-tRNA synthetases
-|--||-------||||||||||||-||||||||||||||||||||||||||||||||||||||--  3 [G] COG0036 Pentose-5-phosphate-3-epimerase
-|||||||||-||||-|-||||----|||-||||---|----|||||-|-||-|||---|-|||--  3 [P] COG0038 Chloride channel protein EriC
||||----||---|||||||||||||||||||||||||----|||||-||||||||||||||||||  3 [J] COG0042 tRNA-dihydrouridine synthase
||||||||||||||||||||||||||||||||||||||-|||||||||||||||||||||||||--  3 [G] COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  3 [R] COG0073 EMAP domain
||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||--||||||||  3 [C] COG0074 Succinyl-CoA synthetase, alpha subunit
|||||||||||||||-||||-|---|||||||||||||--|-||||||||||||||--||||||--  3 [E] COG0078 Ornithine carbamoyltransferase
|||---||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||||  3 [L] COG0084 Mg-dependent DNase
|||||||||||||||-||||-|----||||||--||||----|||||-|||||--|||||||||--  3 [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases
-------------||||||||||||||||||||||||||||||||||-||||||||||||||||||  3 [I] COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase
|-||||-------||-||||||||||||||||||||||||||||||||||||||||||||||||||  3 [L] COG0210 Superfamily I DNA and RNA helicases
|-||------||-||-||||||||||||||||||||||----||||||||||||||||||||||||  3 [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
--||-------------||-||--|||||-||||||||||||||||||||||||||-|||||||||  3 [C] COG0280 Phosphotransacetylase
|||||||||||||||-||||||--||||||||||---|-|--||||||||||||||||||||||||  3 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs
-------------|||-||||-||||||||||||||||-|--|||||-||||||||||-|||||--  3 [G] COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase
|-|||||||-|||||-||||-|--|-|||||--|||||----|||||-||--||||||||||||--  3 [R] COG0388 Predicted amidohydrolase
||||||--||||----|||||-------------|-|-----||||||||||-|||--||||||--  3 [O] COG0425 Predicted redox protein, regulator of disulfide bond formation
|||||||||||||||-|||||||||-||||||||||||----|||||-||||||||||||||||||  3 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase
|||||||||||||||-||||||--|||||-||||||-|-||||||||-||-|---|---|||||--  3 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases
||||||||||||||||||||||----|||||--|||||----|||||-||||||||||||||||||  3 [D] COG0489 ATPases involved in chromosome partitioning
|||||||||||||||||-||||----|||||-||-|||----||||||||||||||||||||||--  3 [O] COG0501 Zn-dependent protease with chaperone function
||-|||||-|--|||-||||||-|-|||||||||||||----||||||||||||||||||||||--  3 [F] COG0516 IMP dehydrogenase/GMP reductase
|||||||||||||||-||||||||-|||||||||||||----|||||-||||||||||||||||||  3 [R] COG0517 FOG: CBS domain
|||||-|||||||||-||||-|||--||||||-|||||----||||||||||||||||||||||||  3 [E] COG0527 Aspartokinases
||||--|||---|||-|||-||--|||||-|||||||||||||||||-||||||||||||||||--  3 [V] COG0534 Na+-driven multidrug efflux pump
---|||||--|-|-----|------------||||-----|-|||-|--||---------|-----  3 [E] COG0549 Carbamate kinase
|-|||||||-|||||||||||-|||||||||||||||||||||||||-||||||||||||||||||  3 [I] COG0558 Phosphatidylglycerophosphate synthase
--------|----||-|||||||||||||||||||||||||||||||-||||||||||||||||||  3 [J] COG0566 rRNA methylases
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  3 [K] COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)
---|---------||||-||-|||--|---------------||||||||||-|||---|||||||  3 [C] COG0633 Ferredoxin
-|||||||||||||||-|||||--------||-|-|||----||||||||||||||--|||-||--  3 [T] COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases
|||-----|--|-----|||----------|-----------|||||---||--------|-----  3 [R] COG0641 Arylsulfatase regulator (Fe-S oxidoreductase)
||||-||||-|||----|||-|----|||-----||||----|||-|-||---------|||--||  3 [CP] COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit
---|||||--||||||-||-------||||||||||||----|||||--|-----|---|||||--  3 [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase
|||-||||-|-|----|-||-|----|||-|-----||----|||-|-||--||||--||||||||  3 [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily
-------------||||||||||||-|||||||-||||----|||||-||||||||--||||||--  3 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
----||----|--|||--||||--|||---|-----------||||--||-|||||--|||-||||  3 [R] COG0666 FOG: Ankyrin repeat
-------------||---||||||-|----|||||||--|--|||||-||||-|||||||||||||  3 [R] COG0670 Integral membrane protein, interacts with FtsH
|||---||||-|----|-||----------|-----------|||-|---------|||-------  3 [C] COG0680 Ni,Fe-hydrogenase maturation factor
---|----|-|-|----|||||--||----||||||--|||||||||-||||-|||---|||||--  3 [E] COG0687 Spermidine/putrescine-binding periplasmic protein
-||||||||||||||-|-||||--||-||-|--|||||-||||||||-||-||--|--||||||--  3 [R] COG0693 Putative intracellular protease/amidase
|-||----|----|||-|||-|----|||||||||||-----|||||-||||||||---|||||||  3 [O] COG0695 Glutaredoxin and related proteins
---|---------||-|-||-|----|----|--||||----|||||-|||-|--|---|||||--  3 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epimerases
-------------||----|-|----|----|-|--------||||||||||||||------||--  3 [E] COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase
--|--|-|-|---|||-|||||||---|||||||||||----|||||-||--|--|||-|||||--  3 [G] COG0726 Predicted xylanase/chitin deacetylase
----------------||||||--||||||||--||||----||||||||||||||||||||||||  3 [M] COG0739 Membrane proteins related to metalloendopeptidases
------------------|-----------------------|||||---|-----||||---|--  3 [E] COG0754 Glutathionylspermidine synthase
-------------|||||||||--||----||||||||----||||||||||||||||||||||||  3 [O] COG0760 Parvulin-like peptidyl-prolyl isomerase
-----------------|---|||||||||||||||||||||||||||||||||||||||||||||  3 [K] COG0782 Transcription elongation factor
-------------|||-----|--------------------|||||-||||-|||||||||||--  3 [R] COG0790 FOG: TPR repeat, SEL1 subfamily
----|---|----||||||--||||-|||-||||||||----||||||||||||||||||||||||  3 [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
----------------|-|||||||||||||---||||----||||||||||||||||||||||--  3 [M] COG0860 N-acetylmuramoyl-L-alanine amidase
--|-||----|||||---||------||||-||||-||----|||-|--|--|||||||||||---  3 [R] COG1064 Zn-dependent alcohol dehydrogenases
|||---||||-|-----|||------|||||-|-||||----|||||--|-----|---|||||--  3 [G] COG1082 Sugar phosphate isomerases/epimerases
-||||||||--||----|||||----|---|-|||||||-|||||||-||||---|||||||||--  3 [PH] COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components
|-||||||||||||||-|||-|---||||||||||||||||-|||||-||-|||||||-|||||--  3 [V] COG1131 ABC-type multidrug transport system, ATPase component
--||--||--||-|||||||||||--||||||||||||||||||||||||||||||||||||||||  3 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components
|||||||||-|||---||||-|-----||-------------||||||-|--||||||||||||||  3 [C] COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)
|||-|||||||||----|||||--------|-----|-----|||||-|||||||||||||-|---  3 [C] COG1145 Ferredoxin
---|||----|||||--|||||----||||-|-|||||----|||||-||||||||--||||||||  3 [E] COG1171 Threonine dehydratase
---|||||--|||----|||-|--|-||||||||||||-||||||||-||-||--|---||||---  3 [G] COG1175 ABC-type sugar transport systems, permease components
---|----|-|-|----|-|||--||----||||||--|||||||||-||||-|||---|||||--  3 [E] COG1176 ABC-type spermidine/putrescine transport system, permease component I
---|----|-|-|----|-|||--||----||||||--|||||||||-||||-|||--||||||--  3 [E] COG1177 ABC-type spermidine/putrescine transport system, permease component II
-------------||-|||||||||||||||||-||||----||||||||||||||||||||||||  3 [J] COG1186 Protein chain release factor B
|-|-||||||||-||||-||------|---|||-||||----|||||--|-----|---|||||-|  3 [M] COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
---|||--|-|||-------||-----||||---|-||----|||||-||-----|---|||||||  3 [I] COG1250 3-hydroxyacyl-CoA dehydrogenase
--||---------||-|||||||||||||-|||||||-||||||||||||||||||||||||||||  3 [R] COG1253 Hemolysins and related proteins containing CBS domains
---|--------------------|-|||-----||||----|||||-||||-||-----|-----  3 [M] COG1292 Choline-glycine betaine transporter
----------|||--------|--||-||-------||----|||----|-----|---||-|---  3 [C] COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs
||||--|||||-|----|-|||--------||||||||||--|||-|--|----------|-----  3 [G] COG1363 Cellulase M and related proteins
-----------------|------------|----|||----|||||-|----------||-|---  3 [G] COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
|||||||||||||--------|----|||-|-----||----|||||-||||-|||---|||||--  3 [K] COG1522 Transcriptional regulators
----------|||---|----|--|--||-------||----|||----|-----|---||-||--  3 [C] COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs
--------------------|-||--||||------------|||||-||||||||||||||||||  3 [M] COG1560 Lauroyl/myristoyl acyltransferase
-|||||-|-----||--|-|||----||||||||||||--|-|||||-||-|-|||||||||||||  3 [J] COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
--|---||--|-|-----||-|----||||||||||||----|||||--|--|--|---|||||||  3 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins
-----|--|-||---------|-----||-------------|||-|--|-----|---|||||--  3 [C] COG1804 Predicted acyl-CoA transferases/carnitine dehydratase
--||||--|||||---|-||-|----||||----||||----|||||-||||||||||||||||||  3 [U] COG1826 Sec-independent protein secretion pathway components
|||---|||||-----||------------|------|----|||||-||--||||-----||---  3 [C] COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain
|||||||||||||----|-|||----||||||||||||----|||||-||--||||---|||||--  3 [K] COG1846 Transcriptional regulators
|||---|||||-----||------------|------|----|||||-||--||||-----||---  3 [C] COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain
-----------|-||----|-|----|||-----|--|----|||-|--|-|---|--||||||--  3 [F] COG1957 Inosine-uridine nucleoside N-ribohydrolase
-------------------|------------|-|-||----|||||-|-||----||-----|--  3 [F] COG1972 Nucleoside permease
-----------------|||-|----||||||--||||----|||||-|||||--|---|||||--  3 [KT] COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases)
----||-----|-||--|||||--------||-|||||----|||-|-|-||-|||---|||||--  3 [G] COG2017 Galactose mutarotase and related enzymes
---|||--|-|||||--|--||----|||||-----||----|||-|--|--||||---|||||--  3 [C] COG2025 Electron transfer flavoprotein, alpha subunit
||----||-|----------------|---|-----|-----|||-|--|||-------||||---  3 [C] COG2055 Malate/L-lactate dehydrogenases
----------|||--------|--||-||-------||----|||----|-----|---||-||--  3 [C] COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs
---|||--|-|||||--|--||----|||||-----||----|||-|--|--||||---|||||--  3 [C] COG2086 Electron transfer flavoprotein, beta subunit
-||-|||||||||---|--|-||||-----------|-----||||||||-|||||--||||||--  3 [U] COG2095 Multiple antibiotic transporter
||||----||-|-------|-|----||||--||||||-|--|||||--|--|--|---|||||--  3 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
--------------------|----||---||||||||-|||||||||||||---|-------|--  3 [G] COG2190 Phosphotransferase system IIA components
------||-----||-||||||||--|||-||||||||----|||||-||||||||--||||||--  3 [J] COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase
----------------------||-------||-|-|-----|||||-||||------|-----||  3 [G] COG2271 Sugar phosphate permease
----||----|||----|--|---------------------|||-|-------------|-|---  3 [C] COG2440 Ferredoxin-like protein
----||||--||--------------|---||||||||----|||||-|----------||--|--  3 [G] COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase
--------------------------|||--|-|---|-|--|||--------|||---||--|--  3 [L] COG2826 Transposase and inactivated derivatives, IS30 family
------------------------------------------|||||-||||------|||-----  3 [C] COG3005 Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit
------------------|-----------------------|||||-||-||-||---|||||-|  3 [C] COG3038 Cytochrome B561
--||---|------|------------||-------------|||||--|||-------|||||--  3 [P] COG3119 Arylsulfatase A and related enzymes
-------------------------------|--||------|||||-||----------|-||--  3 [S] COG3152 Predicted membrane protein
-----------|-----|-------------|||---|----||||------|------||-----  3 [G] COG3250 Beta-galactosidase/beta-glucuronidase
---|-------|------------------------------|||||-|-||---|----------  3 [R] COG3381 Uncharacterized component of anaerobic dehydrogenases
--------------------|---------||||-||-----|||||----|--------------  3 [G] COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB
------------------||----------------------|||---|-----|--|--------  3 [R] COG3596 Predicted GTPase
----------------|-------|-----------------|||-|-||-----|----|-|---  3 [KT] COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains
------------------------------------------|||||---||-||----|||||||  3 [M] COG3637 Opacity protein and related surface antigens
------------------||----------------------|||||-||----||----|-----  3 [UNTP] COG3678 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein
---------------------------||--------|----|||||-|-----------|-|---  3 [K] COG3710 DNA-binding winged-HTH domains
--------------------|-----|---||||||||----|||||-------------------  3 [K] COG3711 Transcriptional antiterminator
--------------------|---------||||-||-----|||||----|--------------  3 [G] COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC
------------------------------------------|||||--|||--------------  3 [M] COG3765 Chain length determinant protein
|||||||||||||---||||||--|-||||||||||||-||||||||-||-||--|--|||||---  3 [G] COG3839 ABC-type sugar transport systems, ATPase components
------------------------------------------|||||--|-|---|----------  3 [S] COG4575 Uncharacterized conserved protein
|||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||--  3 [E] COG4992 Ornithine/acetylornithine aminotransferase
---------------------------||--|--||------|||-|-------------------  3 [R] COG5562 Phage envelope protein
||||||||||||||||||||||||||||||||||||||||||||||||||||||||---|||||||  2 [J] COG0009 Putative translation factor (SUA5)
-------------|||||||-||||-||||||||||||||||||||||||||||||||||||||--  2 [G] COG0021 Transketolase
--||||-|--|||||-||||||----||||||||||||----||||||||||||||||||||||--  2 [E] COG0031 Cysteine synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [D] COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control
|||||||||||||||-||||||----||||||||||||----|||-|--|--|--|||||||||--  2 [F] COG0044 Dihydroorotase and related cyclic amidohydrolases
---------|---||-||||||||||||||||||||||||||||||||||||||||||||||||||  2 [J] COG0050 GTPases - translation elongation factors
-||---||--||-|--|-||||||--|||-||||--||----|||||-||||-------||-|---  2 [G] COG0058 Glucan phosphorylase
|||||||||||||||-||||-|-----||||---|-||----||||||||--|--|---|||||||  2 [O] COG0071 Molecular chaperone (small heat shock protein)
||||--||||--||----||-------||--|---|-|----||||--|-|---------|||---  2 [E] COG0076 Glutamate decarboxylase and related PLP-dependent proteins
||||----|||--||-||||||----||||||||||||----|||||-||||||||||||||||||  2 [EH] COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase
|||--|||||||-||-||||-|----|||||--|||||----||||||||||||||--||||||--  2 [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases
-|-----------|--|-|||--|--|||||---|-||----||||||||||||||||||-|||--  2 [H] COG0132 Dethiobiotin synthetase
|||||-|||||||||-||||-|||--||||||-|||||----||||||||||||||||||||||||  2 [E] COG0136 Aspartate-semialdehyde dehydrogenase
||||||||||||||||||||||||||||||||||||||----||||||||||||||||||||||||  2 [H] COG0142 Geranylgeranyl pyrophosphate synthase
-|-|--||||||||||-|||||||--|||-||||||||----|||||-||||||||--||||||--  2 [J] COG0144 tRNA and rRNA cytosine-C5-methylases
||||||-||||||||-||||||----||||||||||||----||||||||||||||||||||||--  2 [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I
-|--||||-----||||-||||||---|||----|-||----|||||-||||||||||||||||||  2 [H] COG0156 7-keto-8-aminopelargonate synthetase and related enzymes
--||||||--|||||----|-|----|||||---|-||----|||||-|||----|---||||---  2 [E] COG0160 4-aminobutyrate aminotransferase and related aminotransferases
|||||||||||||||-||||||----||||||||||||----||||||||||||||||||||||--  2 [F] COG0167 Dihydroorotate dehydrogenase
||||--||||--|||-||||||--||------||||||-||||||||-||||-||---||||----  2 [P] COG0168 Trk-type K+ transport systems, membrane components
||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||--  2 [E] COG0169 Shikimate 5-dehydrogenase
|||||||||||||||-||||-|----||||-|||||||----|||||-||||||||||||||||||  2 [E] COG0174 Glutamine synthetase
-||||-||-||||||---||||----|||-|-----||----||||||||--||||---|||||--  2 [EH] COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes
--||||--|----|||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
--||||--|----|||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
-|||--|||-|||-----||-|---------------|--||||||||||||||||---|||||--  2 [HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)
---|-------|-||||-|-|||||-||||||||||||-|||||||||||||||||||||-|-|||  2 [F] COG0208 Ribonucleotide reductase, beta subunit
|-|||||||-|||||||||-|||||-||||||||||||-|||||||||||||||||||||||||||  2 [F] COG0209 Ribonucleotide reductase, alpha subunit
-------------||-|||||||||||||||||||||||||||||||-||||||||||||||||||  2 [S] COG0217 Uncharacterized conserved protein
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  2 [J] COG0223 Methionyl-tRNA formyltransferase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [J] COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)
-|--||-------|||--|-|------||-|-----------|||||||||||||||||---||--  2 [E] COG0241 Histidinol phosphatase and related phosphatases
--|--------|-|--||||||----|||||------|----|||||-||||||||||||||||||  2 [FP] COG0248 Exopolyphosphatase
|||||||||||||-|-||||||||||||||||||||||||||||||||||||||||||||||||||  2 [K] COG0250 Transcription antiterminator
|||||||||||||||-----||----||||||||||||----|||||-|||-||||||||-|----  2 [EJ] COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  2 [J] COG0254 Ribosomal protein L31
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0258 5'-3' exonuclease (including N-terminal domain of PolI)
------------|-|||-||||||--||||----|-|||||||||||||||||-||||||||||||  2 [E] COG0260 Leucyl aminopeptidase
------------------||-|----||||-||||||||||||||||-||||||||---|||||-|  2 [L] COG0266 Formamidopyrimidine-DNA glycosylase
|||---|||||||-----------------|-|||-|--||-|||-|-|-||--------------  2 [G] COG0269 3-hexulose-6-phosphate synthase and related proteins
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0272 NAD-dependent DNA ligase (contains BRCT domain type II)
-|--||----------|-|-|------||-|-----------||||||||||-||-|||---|---  2 [G] COG0279 Phosphoheptose isomerase
--|||||||-|||||--|||-|----|||-|||-||||----|||||-||||||||--||||||||  2 [C] COG0281 Malic enzyme
--|--------------|||||--|||||-||||||||||||||||||||||-||-|||-|||-||  2 [C] COG0282 Acetate kinase
|--|------||-||---||-|----|||||-||--||----|||||-||||||||||||||||--  2 [P] COG0288 Carbonic anhydrase
|||---||||--------||----------|-----------|||-|---|-----|||-------  2 [O] COG0298 Hydrogenase maturation factor
-------------||-||||||||--||||||||||||----||||||||||||||||||||||||  2 [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase
||||||||||||-|---|-|-|||--|||||---||||----||||||||||-||||||||-|---  2 [P] COG0306 Phosphate/sulphate permeases
|||-|||||||||---||||-|-----||-|------|----||||||||||||||---|||||--  2 [R] COG0312 Predicted Zn-dependent proteases and their inactivated homologs
----------------||||||---||||||||||||||-|||||||-||||||||||||||||-|  2 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases
|-||------------|||||||||||||||||||||||||||||||-||||||||||||||||||  2 [L] COG0322 Nuclease subunit of the excinuclease complex
-------------||---||-|----|---------------|||||-||||||||---|||||--  2 [E] COG0339 Zn-dependent oligopeptidases
|-||--|||--||||---||||----||||||||||||----|||||-||||||||--||||||--  2 [E] COG0346 Lactoylglutathione lyase and related lyases
|||-----||------||||-|----|||-||---||-----|||||-||||||||---|||||--  2 [E] COG0347 Nitrogen regulatory protein PII
-||-||--||-|------||----------|-----------|||-|-||||-|||||||||||--  2 [C] COG0348 Polyferredoxin
||||||||||||||--||-||-|||-||||||-|||||-|--|||||-||||||||||||||||-|  2 [L] COG0350 Methylated DNA-protein cysteine methyltransferase
|-||||--|-|||||||-||-|-----||--|--||||----|||||-||-||--||-||||||--  2 [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases
|||||||||||||-|--|||----------||||-|||----|||||-------------|-----  2 [C] COG0371 Glycerol dehydrogenase and related enzymes
|-||||--|-|||||-||||-|----||||-|--||||----|||||-||-|||||||||||||||  2 [C] COG0372 Citrate synthase
--|-----||------|--|----------|-----------|||-|---------|||-------  2 [C] COG0374 Ni,Fe-hydrogenase I large subunit
|||---||||------|-||-|--------------------|||-|---------|||-------  2 [R] COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)
--||-------|-||---|||-----|||-|||||||||||||||||-||-|-|||---|||||--  2 [L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair
|-||----|----||-|-||-|----|||-||||||||----|||-|-||-|||||--||||||--  2 [T] COG0394 Protein-tyrosine-phosphatase
---|||||--|||----|||-|--|-||||||||-|||-||||||||-||-||--|---||||---  2 [G] COG0395 ABC-type sugar transport system, permease component
--||---------||---||------|||-||||||||----|||---|-----------|--|--  2 [S] COG0398 Uncharacterized conserved protein
||-----|-||-----||||----|-|||-|--|--|-----|||||-||-|-||||||-||||--  2 [M] COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis
--|-||-----|-||-||||||----||||||||||||----|||||-||-||--|---|||||--  2 [G] COG0406 Fructose-2,6-bisphosphatase
--|-|------|-||-|-||-------|||------|-----|||||--|-----|---||-||--  2 [Q] COG0412 Dienelactone hydrolase and related enzymes
--|---||-----||-||||||||--|||||-----||----|||||-||-|||||||||||||||  2 [D] COG0424 Nucleotide-binding protein implicated in inhibition of septum formation
---|---------||---||-|----|||--|||||||--|||||||-||-|-|||---||-||--  2 [R] COG0431 Predicted flavoprotein
|||---||||--|||-||||-|----||||||-|||||----||||||||||-|||--||||||--  2 [E] COG0440 Acetolactate synthase, small (regulatory) subunit
||||||||||||||||||||||----|||||||||||||---|||||-||||||||--||||||--  2 [R] COG0456 Acetyltransferases
|||||||||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  2 [E] COG0460 Homoserine dehydrogenase
-|||||||--||||||-|||||||-|||||||||||||||||||||||||||||||--||||||--  2 [G] COG0469 Pyruvate kinase
||----||-|||-||-||||||||||||||||||||||----|||||||||||||||||||||-||  2 [M] COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase
|||---||||||-||-||||-|----||||||--||||----||||||||||||||--||||||||  2 [CE] COG0473 Isocitrate/isopropylmalate dehydrogenase
|||-|||||-|||||-|-||-|---|-|||||--||||----|||||-|||-||||||||||||||  2 [P] COG0475 Kef-type K+ transport systems, membrane components
|-|||||||-|||||||-||||----|||||--|||||----|||||-||||||||||||||||--  2 [H] COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||||||||||||  2 [C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit
||||||||||||||||||||||----||||||||||||----||||||||||||||||||||||--  2 [R] COG0491 Zn-dependent hydrolases, including glyoxylases
||||--||-||||||--|||||--|||||-||||||||||||||||||||||-||||||||||---  2 [F] COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins
---|||----|||||---||-|||--||||-|||||||-|||||||||||||||||---|||||||  2 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes
||||||-||||||||-||||||----||||||||||||----||||||||||||||||||||||--  2 [EH] COG0512 Anthranilate/para-aminobenzoate synthases component II
|-||--||-|-||-|--||||||||||||||||||||||||||||||-|||||--|||||||||--  2 [E] COG0520 Selenocysteine lyase
|||||||||||||---|--|-|----|||||---||||----|||||-||||---|||||||||--  2 [H] COG0521 Molybdopterin biosynthesis enzymes
--|----------||-|-||||----|||-----|-||----|||||-||--||||||-|||||--  2 [R] COG0523 Putative GTPases (G3E family)
|------------||||||||||||||||||||||||||-|||||||-||||||||||||||||||  2 [O] COG0542 ATPases with chaperone activity, ATP-binding subunit
-------------||---||-||||-|---------------||||||||||||||-------|--  2 [O] COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1
||||||-||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  2 [E] COG0547 Anthranilate phosphoribosyltransferase
|||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||-|  2 [E] COG0548 Acetylglutamate kinase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0550 Topoisomerase IA
|||||||||--------|--|-|||-----|||||||||-|||||||||||||||||||-------  2 [L] COG0551 Zn-finger domain associated with topoisomerase type I
|||||||||||-|||-----|--|--||||||----------|||||-||||||||||||||||--  2 [E] COG0560 Phosphoserine phosphatase
||||||--||-||-----||-|--------------------|||||-||||||||---|||||-|  2 [J] COG0565 rRNA methylase
---|||-----|-|||--|--|---|||||-|||||||----|||||-|||||--|---||||---  2 [C] COG0578 Glycerol-3-phosphate dehydrogenase
----|--||---|----||||-----|||-|---|--|-||||||-|-||--||||||||||||--  2 [R] COG0579 Predicted dehydrogenase
|-------|--|-|||-||-||---|----||||||||-|||||||||-||||--|---|||||--  2 [G] COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)
---|||-|--|-||||-|-|||--|-||||||||||||-||||||||-||||---|---|||||--  2 [C] COG0584 Glycerophosphoryl diester phosphodiesterase
----------------||||-|||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0593 ATPase involved in DNA replication initiation
-||---|-|-||-||-||||||----|||||||||||-----|||||-|||||--|||||||||-|  2 [P] COG0598 Mg2+ and Co2+ transporters
-||-----||-------|||||||--|---|--||-||----||||---|||---|---|||||--  2 [P] COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component
||||||||||||----|-|||---------||||||||----|||||-||||||||||||||||||  2 [O] COG0602 Organic radical activating enzymes
--||||----||-||-|--|-|----||||-|--||||----|||||-||-||--|---|||||--  2 [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases
|-||||----|||||||-||-|||-|||||||||||||----||||||||||||||||||||||||  2 [P] COG0605 Superoxide dismutase
----------|-|||-||||||---|-|||||||||||----|||||-|||||--|||||||||||  2 [R] COG0612 Predicted Zn-dependent peptidases
-||||||||-|||----|||||----||||||||||||----|||||-||||---|||||||||--  2 [P] COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component
|||||||||-|-|---|||||||||-||||-----|||----||||||||||||||||||||||||  2 [OU] COG0616 Periplasmic serine proteases (ClpP class)
-------------|||||||||||||||||||||||||----||||||||||||||||||||||||  2 [J] COG0617 tRNA nucleotidyltransferase/poly(A) polymerase
|||||||||||||---||||||-||-|||||---|-||----||||||||||||||||||||||||  2 [J] COG0621 2-methylthioadenine synthetase
--||||||--|||||--|--||----||||||||||||----|||||-||||||||||||||||--  2 [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases
-------------|----||------||||-|||||------|||||--|||-|||---|||||--  2 [R] COG0627 Predicted esterase
----------------|||||||||||||-|||||||||---||||||||||||||||||||||||  2 [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases
|||||||||||||---||||||----|||||||-||||----|||||-||-|||||--||||||--  2 [K] COG0640 Predicted transcriptional regulators
|||--|||-|-|-----|---------||-------------|||-|-------------------  2 [C] COG0650 Formate hydrogenlyase subunit 4
|-||---------|||--||||--|-||||||||||||----|||||-||||||||||||||||--  2 [O] COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
-|-|----|-|||----|||||----|------|---|----|||||--|-----|--|||||---  2 [E] COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
--|----------||-||||||||--||||||||||||----||||||||||||||||||||||--  2 [E] COG0703 Shikimate kinase
|||||||||||||---||||-|---||||||---||||----|||||-||--|--|---|||||--  2 [R] COG0714 MoxR-like ATPases
|||||||||||||----|||-||||-||||||||||||----|||||-----|------|||||--  2 [O] COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component
--|-||--|-|||---||||||---||||||||-||||--|||||||-||||||||||||||||--  2 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins
|--|----|----||-|||--|--|-|---|||-||||-|--|||||-|-||---|||-||-|---  2 [F] COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases
-----------------|||||----||||||||||||----||||||||||||||||||||||--  2 [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein)
----------------||||||||------||||||||----||||||||||||||||||||||||  2 [I] COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases
----------------||||||||||||||||||||||----||||||||||||||||||||||||  2 [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2
----------------||||||||||||||||||||||----||||||||||||||||||||||||  2 [D] COG0772 Bacterial cell division membrane protein
----------------||||||||||||||||||||||----||||||||||||||||||||||||  2 [M] COG0773 UDP-N-acetylmuramate-alanine ligase
--|--------------|--|||||||||-||||||||||--||||||||||-|||||||||||--  2 [F] COG0775 Nucleoside phosphorylase
--------------|-|-||||--||||||||||||||----|||||-||||||||||||||||||  2 [M] COG0787 Alanine racemase
|||---|||||||---|---|-||------|---|||-----|||||-||||||||||||||||||  2 [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation
-----------------|||||||||----------------|||||-||||||||||||||||||  2 [R] COG0795 Predicted permeases
-----------------|||----|-----||||--||----|||||-||||||||||-|||||--  2 [G] COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase
|-|------|------|-||||||------------------|||||-||||||||||||||||||  2 [U] COG0811 Biopolymer transport proteins
|-||||----|||---|-||||--|-|||-|---||||----|||||-||||||||||||||||--  2 [R] COG0824 Predicted thioesterase
-------------||---------------||--|||-----|||||--|-----|||--------  2 [E] COG0833 Amino acid transporters
----------------|-||||||------------------|||||-||||||||||||||||||  2 [U] COG0848 Biopolymer transport protein
--||||-||-|||---|-||-|----|||-----||||----||||||||--||||||||||||||  2 [CP] COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit
-----------------|---|--------||||||||-|--|||||||-------||-||-|---  2 [G] COG1015 Phosphopentomutase
--||----------|--|||------||||||||||||----||||||||||-|||||||||||--  2 [E] COG1045 Serine acetyltransferase
|||||||||||||-------||--|-----------------|||||-|||||||||||-------  2 [O] COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2
--||||----|||||-|----|----||||||--|||-----|||||-||--||||---|||||||  2 [C] COG1048 Aconitase A
----||||--|||||-|-|||---|-----|-|-||||----|||||-||||-|||||||||||--  2 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases
||-|||--|||||||-||||||||--||||||--||||----|||||-||||||||||||||||||  2 [C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit
----|||||-|||----||||-||---|||----||||----||||--||---|||--||--|---  2 [P] COG1055 Na+/H+ antiporter NhaD and related arsenite permeases
-----|-------||-----------||||-|||-|||----|||||-|-||-------||||---  2 [H] COG1072 Panthothenate kinase
-------------|||--|-----------------------||||||||||-|||--||||||||  2 [O] COG1076 DnaJ-domain-containing proteins 1
|-|--||||--||-|---||||----|||||||---||----|||||--|||||||---||-||--  2 [M] COG1088 dTDP-D-glucose 4,6-dehydratase
-|----||-|--|---||--||||-------||||||-----||||||||||||||---||||---  2 [R] COG1092 Predicted SAM-dependent methyltransferases
-----------------|--||---||||-||||||||--|||||||-||||---|----------  2 [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)
|||||||||||||||||||||||||||||||||||||||-||||||||||||||||||||||||||  2 [G] COG1109 Phosphomannomutase
--|--|--------------|-||--------|-|--|||--|||||------------||||---  2 [EP] COG1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
||||----|||||---|||||||||||||-||||||||||||||||||||||||||||||||||||  2 [V] COG1136 ABC-type antimicrobial peptide transport system, ATPase component
--|-----|-|-|--------|--------------------|||||-|||||------|||||||  2 [O] COG1138 Cytochrome c biogenesis factor
----------|-|-------------|||-----|-|-----|||-|--|-----|-----|----  2 [C] COG1140 Nitrate reductase beta subunit
----||||--|||||--|-|||----|||||-||||||----|||||-||-|---|---|||||--  2 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
---|--------------||------||||-|--|||-----|||||-||||---------|----  2 [HQ] COG1169 Isochorismate synthase
--------|----------|||-----||-|||||||-----|||||--|-----|||-||||---  2 [E] COG1174 ABC-type proline/glycine betaine transport systems, permease component
---|--||--|-|-----||||--|-|------|---|----|||||-||||-|||--|||||---  2 [P] COG1178 ABC-type Fe3+ transport system, permease component
--|-------------||||||||||||||||||||||----|||||-||||||||||||||||||  2 [M] COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes
--|-------||-|||||||||||--|||||||||||||||||||||||||||||||||||-----  2 [J] COG1190 Lysyl-tRNA synthetase (class II)
||||||||--|||||||-|||-----|||-||||||||----|||||-||||||||-------|--  2 [KL] COG1199 Rad3-related DNA helicases
|-|||||||--||----|||-|----|||||||---||----|||||--|--||||---||-||--  2 [M] COG1209 dTDP-glucose pyrophosphorylase
|||----|---|----|--||----|||||||||||||--|||||||-||||||||||||||||--  2 [M] COG1210 UDP-glucose pyrophosphorylase
-----------------|||----------|----||-----|||||-||-----|----------  2 [KT] COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
--||||--|-------|-||--||--|||--|--||||----|||||-||||---|--||||||||  2 [C] COG1271 Cytochrome bd-type quinol oxidase, subunit 1
--||------------|-||--||--|||--|--||||----|||||-||||---|--||||||||  2 [C] COG1294 Cytochrome bd-type quinol oxidase, subunit 2
--|-------------|-||||||--||||||||||||-|--|||||-||||||||||||||||||  2 [S] COG1295 Predicted membrane protein
----------------||----||||----|----|||----||||||||-----|||||||||--  2 [NU] COG1298 Flagellar biosynthesis pathway, component FlhA
--||--||----|---|--||||||||||-|---|-||----|||||-||--|--|--|||-||||  2 [C] COG1301 Na+/H+-dicarboxylate symporters
----------------||------||----|----|||----|||||-||-----|||||||||--  2 [N] COG1344 Flagellin and related hook-associated proteins
--||--------------||-|--|-|||-||---|||----|||||--|-|-------||-||||  2 [S] COG1357 Uncharacterized low-complexity proteins
--||--------------|-||----|||-||-|-||-----|||||-||-|-|||---||-||--  2 [S] COG1359 Uncharacterized conserved protein
----------------||------||----|----|||----|||||-||-----|||||||||--  2 [N] COG1360 Flagellar motor protein
----------------||||-|----|---||--||------|||||-||||||||---|||||||  2 [S] COG1434 Uncharacterized conserved protein
---------------------------------|--|-----|||-|---||----||--|---||  2 [M] COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases
-------------||-----|-||------------------|||||-||||||||----|-|---  2 [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase
----------------||||||||------||||||||----|||||-||||||||------||--  2 [NU] COG1459 Type II secretory pathway, component PulF
--------------------||-||-|---||||||||----|||||-||||||||||||||||--  2 [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen
-----------|--|--|||-|---|||||||---|||----|||||-||||||||---|||||||  2 [G] COG1472 Beta-glucosidase-related glycosidases
--||||||---|-----|||||----|||-||-|||||----|||----|||---|--||||||--  2 [R] COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase
||-|--|||-|||---|--|-|||||||||||||||||----|||||-||--||||||||||||||  2 [K] COG1475 Predicted transcriptional regulators
--|-------------|----------||-|||||||||---||||||-------|---||-|---  2 [L] COG1484 DNA replication protein
--|---------------||||----|||||-----||----|||-|-|-||---------|||--  2 [G] COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins
----||----||-||--|-|----------||-|-|-|----|||||--------|---|---|--  2 [G] COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases
|-|-----|------|-|--------|||-|---|--||---|||||-|-||----|||-------  2 [P] COG1528 Ferritin-like protein
---|--||-||||---|||||-||--|||||----|-|----||||||||||||||---|||||||  2 [J] COG1530 Ribonucleases G and E
-------------||---||||||--||||||||||||----|||||-||||||||||||||||--  2 [H] COG1539 Dihydroneopterin aldolase
----------------||||||-|-|||||||||||||----|||||-|||||--|---|||||||  2 [J] COG1544 Ribosome-associated protein Y (PSrp-1)
---|------------||||||----|||||-||-||||||||||||-||--||||||||||||--  2 [R] COG1546 Uncharacterized protein (competence- and mitomycin-induced)
|||------|-------|------------------------||||||||||--------------  2 [P] COG1553 Uncharacterized conserved protein involved in intracellular sulfur reduction
-----------------|||||--|-||||||--||||----|||||-||||||||---|||||--  2 [K] COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
----------------||||----------------------|||-|-||-|||||--||||||--  2 [M] COG1596 Periplasmic protein involved in polysaccharide export
||||||--|||||||-||--||----||||||||||||----||||||||||||||||||||||--  2 [E] COG1605 Chorismate mutase
---|----||-|---------|---|--------|-||----|||-|-||||-||||||--|----  2 [C] COG1620 L-lactate permease
-------------|||---|----||----------------|||-|--|-----|----------  2 [G] COG1626 Neutral trehalase
-------------|||-----|--|||---------------|||||-||||||||---|||||--  2 [L] COG1643 HrpA-like helicases
---|----|-|-----|-||-|||--||||----|||-----|||||-||||||||||||||||||  2 [O] COG1651 Protein-disulfide isomerase
---|||||--|||----|||-|--|-||||||||-|||----|||||-||-||--|---||||---  2 [G] COG1653 ABC-type sugar transport system, periplasmic component
|||||||||||||--|||-|-|----|||-|------|----|||-|--|-----|----------  2 [S] COG1690 Uncharacterized conserved protein
---------||-|---||||-|----||||-|||||||----|||||-||-|||||---|||||--  2 [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase
----------------|-----||||----|-----||----||||||||||||||--||||||||  2 [T] COG1734 DnaK suppressor protein
--|-----|-------|--|----------|-----------|||-|---------|||-------  2 [C] COG1740 Ni,Fe-hydrogenase I small subunit
--|-||----|-------||------|||-|-----------|||||-||-|---|---|||||--  2 [R] COG1741 Pirin-related protein
-----------|-----|-|||---||||-||||||||-|--|||||-|||||------|||||--  2 [G] COG1820 N-acetylglucosamine-6-phosphate deacetylase
||||--||||-||---|--|--||------------------|||||----|-------||-|---  2 [G] COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes
--|-------------|-||-|----|||-|----|||----|||||-||------------||--  2 [KT] COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
|-|-|-|||-|||-|-||||||----||||||-|||||----|||||--|-|-|||---|||||||  2 [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family
|-|||||||--|-|--|-----||--|||||---|-|-|---|||-|-|--|||||||-||-|--|  2 [R] COG1881 Phospholipid-binding protein
---|--|||||||||------|------------||------|||||-||-|----||||||||--  2 [R] COG1896 Predicted hydrolases of HD superfamily
--||||--|--|-||--|-|||----|||-|||-||||-|--|||||-||--|--|---|||||--  2 [C] COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family
------------------|-------|||-||||||||----|||||-||||-||-----------  2 [G] COG1929 Glycerate kinase
------------------||-|----||||||--||||----|||-|--|-----|--|||-----  2 [S] COG1937 Uncharacterized protein conserved in bacteria
----------------||||||-----||-||-|||||----|||||-||||||||--||||||||  2 [K] COG1959 Predicted transcriptional regulator
--|----|--|-|---|---|-----|||-||----||----|||||-||||-||||||-------  2 [T] COG1966 Carbon starvation protein, predicted membrane protein
----------|||--------|-----||-------||----|||----|-----|---|||||--  2 [O] COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family
|||---||||--|-----------------|---||||----|||||--|-|--------------  2 [R] COG1988 Predicted membrane-bound metal-dependent hydrolases
||||--||||------||||-|----|||-||||||||----|||||-||||||||--|---||--  2 [NOU] COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
------------------|||-----|---------||----|||||-||-----|---|||||--  2 [E] COG2066 Glutaminase
-------------||---||----------|---|-||----|||-|---|||--|----------  2 [H] COG2091 Phosphopantetheinyl transferase
--|-----|----------|-|----|||||--||-||----|||||--|---|||---|||||--  2 [S] COG2128 Uncharacterized conserved protein
---|------|--||-|--|------|||-------||----|||||--|||||||--||||||--  2 [Q] COG2132 Putative multicopper oxidases
--||||----||--|---||-|----||------|-||----|||||--|--|--|---||-||--  2 [PR] COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases
---|-------------|||-------||----||-------|||-|-|----------|-----|  2 [D] COG2161 Antitoxin of toxin-antitoxin stability system
------------------||-|||---||-------------|||||-|||||------|||||--  2 [R] COG2166 SufE protein probably involved in Fe-S center assembly
--------|-|-|-------------|||-----|-|-----|||-|--|-----|-----|----  2 [C] COG2180 Nitrate reductase delta subunit
--------|-|---------------|||-----|-|-----|||-|--|-----|-----|----  2 [C] COG2181 Nitrate reductase gamma subunit
--|-----------------||---|----||||||||----|||||-|-||------|-|--|--  2 [E] COG2195 Di- and tripeptidases
------------------------------|--|||||-||-|||||||--|--------------  2 [G] COG2213 Phosphotransferase system, mannitol-specific IIBC component
|-||||-||-|||||-|||||||||-|||||||||||||---|||||-||||-|||||||||||--  2 [P] COG2217 Cation transport ATPase
|-----||-|-------|--||--------|-||-||-----|||||--|--|------|||||--  2 [M] COG2222 Predicted phosphosugar isomerases
----------------|---------||||----|-||----|||-|--|-----|----||-|--  2 [P] COG2223 Nitrate/nitrite transporter
----------||-|-------|----||||-------|----|||||-||-----|---|||||--  2 [C] COG2225 Malate synthase
|-||--||||---||-|--|-------||-|-----||----|||-|-||--|----------|--  2 [R] COG2234 Predicted aminopeptidases
-------------||------|---||---|-|---------|||||--|||-------|||||--  2 [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase
---|-------|-||----|-|----||||----|-||----|||||-||||-|||---|||||--  2 [S] COG2259 Predicted membrane protein
-------------------|-|----||||-||||-|-----|||||--|-----|---|||||--  2 [S] COG2261 Predicted membrane protein
-------||----||--|-|||----||||||--||||----|||||-||||---|---|||||--  2 [I] COG2267 Lysophospholipase
--------------------||----|----|||-||-----|||||--|-----|---|--||--  2 [S] COG2315 Uncharacterized protein conserved in bacteria
-------------------|-|---------------|----|||--------|||---|------  2 [T] COG2336 Growth regulator
-------------------|-|-----||-|---||||----|||-------|||----|||---|  2 [T] COG2337 Growth inhibitor
-----------------|-|||--------------------|||||--|-||--|---||-||||  2 [R] COG2373 Large extracellular alpha-helical protein
-------------||-----||---------|--||-|----||||-----|-------||||---  2 [G] COG2376 Dihydroxyacetone kinase
--------------------||----|||||---||||----|---|-||--|-||--||||||--  2 [K] COG2378 Predicted transcriptional regulator
---------------------|----|---|---||||----|||-|--|----------------  2 [P] COG2382 Enterochelin esterase and related enzymes
---------------------|--------||||||||----|||||-|--|---|---||||---  2 [K] COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
---|||---|||-----|---|------------|-------|||||-||--|--|--|||||---  2 [R] COG2391 Predicted transporter component
----------|-|------||-----||-|-||||||-----|||||-||||-|||---|||||--  2 [S] COG2606 Uncharacterized conserved protein
------------------------------|-----------|||||-|-||----|||-------  2 [R] COG2704 Anaerobic C4-dicarboxylate transporter
----|------|------------------|-----||----|||||--------|--||||||--  2 [G] COG2721 Altronate dehydratase
----------------||||||||------||||||||----|||||-||||||||--|---||--  2 [NU] COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB
---------------------|----|---|--|-||-----|||-|--|-----|--|--|----  2 [P] COG2807 Cyanate permease
-|----||-|-|-----|---|---------|||||||----||||||||||-------|||||--  2 [J] COG2813 16S RNA G1207 methylase RsmC
---------------------|--------|-----------|||||-||||-|||----|---||  2 [R] COG2823 Predicted periplasmic or secreted lipoprotein
-------------------|-|----|||-----|||-----|||||-||-|-|||------|---  2 [P] COG2837 Predicted iron-dependent peroxidase
------------------------|-----------------||||||||||||||---|||||--  2 [S] COG2840 Uncharacterized protein conserved in bacteria
---|------||---------|----|----||---||----|||||-||||---|--||||||--  2 [S] COG2860 Predicted membrane protein
--|-----|-------|-------------------------|||||-||||---|--|-|-----  2 [C] COG2864 Cytochrome b subunit of formate dehydrogenase
------------------------------------------|||||--|---|||--|-------  2 [S] COG2879 Uncharacterized small protein
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [J] COG2890 Methylase of polypeptide chain release factors
--------------------|---------||||-||-----|||||----|||||---|||||--  2 [G] COG2893 Phosphotransferase system, mannose/fructose-specific component IIA
|--|------|||||-|--|-|----||||-------|----|||||-||-----|---|||||--  2 [P] COG2897 Rhodanese-related sulfurtransferase
------------------------------------------|||||||-|||--|----------  2 [R] COG2916 DNA-binding protein H-NS
-------------------|-|--------------------|||||-|-||--------------  2 [S] COG2949 Uncharacterized membrane protein
------------------------------------------|||||-||---|||----|||-||  2 [M] COG2982 Uncharacterized protein involved in outer membrane biogenesis
---|----------------|-----|---------------|||||-|-||--------------  2 [R] COG2985 Predicted permease
------------------------------------------|||||-|-||-|||----------  2 [S] COG2995 Uncharacterized paraquat-inducible protein A
------------------------------------------|||||-||||-|||----------  2 [R] COG3008 Paraquat-inducible protein B
--------------------|---------------------|||||-||||||||---|||||-|  2 [V] COG3023 Negative regulator of beta-lactamase expression
--||----------------------||-------|||----|||||-||-|-||----||||---  2 [R] COG3030 Protein affecting phage T7 exclusion by the F plasmid
----------------|-------------------------|-----|-----------------  2 [U] COG3031 Type II secretory pathway, component PulC
------------------------------------------|||||-|-|||-------------  2 [M] COG3065 Starvation-inducible outer membrane lipoprotein
------------------------------------------|||-|-|-||--------------  2 [C] COG3069 C4-dicarboxylate transporter
--------------------|-----------||--------|||||-|-|-|------||----|  2 [L] COG3077 DNA-damage-inducible protein J
---------------------|--------------------|||||--||||------|||||--  2 [O] COG3088 Uncharacterized protein involved in biosynthesis of c-type cytochromes
-------------------||-----|---------------|||---|||-|-------|-||--  2 [R] COG3093 Plasmid maintenance system antidote protein
------------------------------------------|||||-||||--------------  2 [S] COG3111 Uncharacterized conserved protein
------------------------------------------|||-|-||--|--|----------  2 [P] COG3131 Periplasmic glucans biosynthesis protein
------------------------------------------|||||-||-|---|----------  2 [R] COG3150 Predicted esterase
--|----------------|------|----|--||------|||||-||---------|||||--  2 [R] COG3153 Predicted acetyltransferase
----------------||||----------------------|||-|-||-||--|---|||||--  2 [M] COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis
|||--|||-|-|---------------||-------------|||-|-------------------  2 [C] COG3260 Ni,Fe-hydrogenase III small subunit
|||--|||-|-|---------------|--------------|||-|-------------------  2 [C] COG3261 Ni,Fe-hydrogenase III large subunit
--|---||-------------------|--------------|||-|-------------------  2 [C] COG3262 Ni,Fe-hydrogenase III component G
------------------|-----------------------|||||--|||---|---|||||--  2 [M] COG3264 Small-conductance mechanosensitive channel
-------------||----|-|----|---------------|||||-||-|-|||---||-|---  2 [G] COG3265 Gluconate kinase
--------------------|-------------|-|-----|||||-|-----------|-----  2 [T] COG3275 Putative regulator of cell autolysis
--------------------|---------||||||||----|||||-||--|--|---|||||--  2 [KT] COG3279 Response regulator of the LytR/AlgR family
--------------------------|-----|---||----|||-|-|-----------------  2 [T] COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism
------------------------------------------|--|--||-------------|--  2 [U] COG3297 Type II secretory pathway, component PulL
----------------|-------------------------|||||---||----------|---  2 [R] COG3302 DMSO reductase anchor subunit
-----------|---------|---------------|----|------------|----|-----  2 [S] COG3396 Uncharacterized conserved protein
--------------------------|---|-||||-|-||-|||-|-|--|--------------  2 [G] COG3414 Phosphotransferase system, galactitol-specific IIB component
------------------------------|----|||----|||-|--------|------||--  2 [L] COG3449 DNA gyrase inhibitor
--------------------------|---------------|||||--|||---|----|||---  2 [G] COG3622 Hydroxypyruvate isomerase
--------------------------------||-----||-|||||-|-||--------------  2 [G] COG3623 Putative L-xylulose-5-phosphate 3-epimerase
---|------|--------||-----|----|--|--|-|||||||---|---------||-||--  2 [P] COG3639 ABC-type phosphate/phosphonate transport system, permease component
-------------------|----------------------|||-|--|---------||-|---  2 [S] COG3685 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  2 [S] COG3691 Uncharacterized protein conserved in bacteria
--------------------|---------------------|||||-|--|---|---||-||--  2 [M] COG3713 Outer membrane protein V
--------------------|---------||||-||-----|||||----|--------------  2 [G] COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID
------------------------------------------|||||-|--|--------------  2 [K] COG3722 Transcriptional regulator
-------------------|----------|-----------|||||-----|--|------||-|  2 [R] COG3772 Phage-related lysozyme (muraminidase)
------------------------------|-||||-|----|||-|-------------------  2 [G] COG3775 Phosphotransferase system, galactitol-specific IIC component
-------------------|||--------------------|||--------------|--|---  2 [S] COG3831 Uncharacterized conserved protein
---------------------|------------|-------|||||--|-|---|---||||---  2 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase
------------------------------------------|||||-||||-|||----------  2 [T] COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific
------------------------------------------|||||-||||-------||-|---  2 [E] COG4160 ABC-type arginine/histidine transport system, permease component
------------------------------------------|||||-||||-------||-|---  2 [E] COG4215 ABC-type arginine transport system, permease component
------------------------------------------|||-|-----|------|------  2 [L] COG4220 Phage DNA packaging protein, Nu1 subunit of terminase
------------------------------------------|||||--||||------|||||--  2 [O] COG4235 Cytochrome c biogenesis factor
------------------------------------------|||||-|-------------|---  2 [M] COG4238 Murein lipoprotein
---------------------|-------------|||----|||||-|-----------------  2 [R] COG4533 ABC-type uncharacterized transport system, periplasmic component
--------------------------|-----|---||----|||-|-|-----------------  2 [KT] COG4565 Response regulator of citrate/malate metabolism
------------------------------------------|||||--------|---||-|---  2 [G] COG4573 Predicted tagatose 6-phosphate kinase
------------------|||--------------|------|||-|-------------------  2 [QC] COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein
------------------------------------------|||||-|------|----------  2 [G] COG4580 Maltoporin (phage lambda and maltose receptor)
--|-------------|---||--||----|-----------||||||||||||||||||||||||  2 [M] COG4591 ABC-type transport system, involved in lipoprotein release, permease component
--|||||||-|||---||--||||-||---||||||||-||||||||-||||---||||||||---  2 [E] COG4608 ABC-type oligopeptide transport system, ATPase component
-----------------|||------|||-------------||||---|-----|---|||||--  2 [PR] COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit
---------------------|--------||-|||||--|-||||||||||---|----------  2 [G] COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain
------------------------------------|-----|||||--------|----------  2 [S] COG4682 Predicted membrane protein
------------------------------------------|||||-||--------||------  2 [P] COG4771 Outer membrane receptor for ferrienterochelin and colicins
------------------------------------------|||||-|||||--|-------|--  2 [U] COG4795 Type II secretory pathway, component PulJ
------------------------------------------|||-|--|--|--------|----  2 [T] COG4943 Predicted signal transduction protein containing sensor and EAL domains
----------|-|-------------|||-----|-|-----|||-|--|-----|-----|----  2 [C] COG5013 Nitrate reductase alpha subunit
---------------------|--------------------|||||-|-||-||-----------  2 [S] COG5339 Uncharacterized protein conserved in bacteria
------------------------------------------|||||------------|---|--  2 [S] COG5463 Predicted integral membrane protein
------------------------------------------|||||--|||--------------  2 [R] COG5645 Predicted periplasmic lipoprotein
||||||--|||||-|-|-||||||--|||||---||||----|||||-||-|||||||||||||--  1 [H] COG0001 Glutamate-1-semialdehyde aminotransferase
|||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||--  1 [E] COG0002 Acetylglutamate semialdehyde dehydrogenase
|||-||--||-|-||-||||-|----|||-||--|||||---|||||--|--||||---|||||--  1 [P] COG0004 Ammonia permease
|||||||||||||||-||||-------||||-||-|||----|--||--|--|------||-|---  1 [F] COG0005 Purine nucleoside phosphorylase
||||||--|||||||-|-||||----|||||---||||----||||||||--||||---|||||--  1 [H] COG0007 Uroporphyrinogen-III methylase
|||||||||||||||---||||--------|-|-|-||----|||-|-||-|||||||-||||---  1 [E] COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0012 Predicted GTPase, probable translation factor
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0013 Alanyl-tRNA synthetase
--|----------||-||||-|--|-||||||||-|||----|||||-||||||||--||||||--  1 [E] COG0014 Gamma-glutamyl phosphate reductase
||||||||||||-||-||||||----||||||||||||----||||||||||||||||||||||--  1 [F] COG0015 Adenylosuccinate lyase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0016 Phenylalanyl-tRNA synthetase alpha subunit
||||||||||||||||--||||--||----|||||||||||||||||||-|||-------------  1 [J] COG0017 Aspartyl/asparaginyl-tRNA synthetases
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0018 Arginyl-tRNA synthetase
|||-||--||---||-||||-|----||||||-|||||----||||||||||||||||||||||--  1 [E] COG0019 Diaminopimelate decarboxylase
||||||||||||||||||||||||||||||||||||||----||||||||||||||||||||||||  1 [I] COG0020 Undecaprenyl pyrophosphate synthase
|||||||||||||||---||----------------------|||||-||||--------------  1 [J] COG0023 Translation initiation factor 1 (eIF-1/SUI1) and related proteins
||||||||||||||||||||||||||||||-|||||||||||||||||||||||||||||||||||  1 [J] COG0024 Methionine aminopeptidase
||||||-|||---|||--||-|----|||--|-||||-----|||||-||-||------|--|---  1 [P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters
---|||----||-||-||||-|----||||-|||||||----|||||-||||||||---|||||--  1 [F] COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)
-|----||---|------||------|||-------|-----|||||-||-|--------------  1 [F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)
---|--||---|----|-|||------||||----|||----|||||-||--||||---||-||--  1 [H] COG0029 Aspartate oxidase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0030 Dimethyladenosine transferase (rRNA methylation)
-------------||---|--|----|||-------------|||||-|----------|||||--  1 [G] COG0033 Phosphoglucomutase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase
|--|---|--|||||-||||||--|-|||-|||||||||||||||||-||||-|||--||||||--  1 [F] COG0035 Uracil phosphoribosyltransferase
||||||--|||||||-||||||||-|||||||||||||-||||||||-|-|||--|--||||||||  1 [C] COG0039 Malate/lactate dehydrogenases
||||----||||-||-||||-|----||||||--||||----|||||||||||||---||||||--  1 [E] COG0040 ATP phosphoribosyltransferase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase
|||-||||||||||--|-||-|||------------||----|||||-||-|-|||||||||-|||  1 [H] COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases
||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||--||||||||  1 [C] COG0045 Succinyl-CoA synthetase, beta subunit
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0048 Ribosomal protein S12
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0049 Ribosomal protein S7
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0051 Ribosomal protein S10
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0052 Ribosomal protein S2
||||---||||||||-||||||---||||-||||||||----|||||-||-|---|--||||||||  1 [P] COG0053 Predicted Co/Zn/Cd cation transporters
||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG0054 Riboflavin synthase beta-chain
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0055 F0F1-type ATP synthase, beta subunit
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0056 F0F1-type ATP synthase, alpha subunit
|||----|||||-|--||||-|----||||||-|||||----||||||||||||||||||||||--  1 [EH] COG0059 Ketol-acid reductoisomerase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0060 Isoleucyl-tRNA synthetase
|||||||||||||||||||||---|||||||||||||||-||||||||||||||||||||||||||  1 [G] COG0061 Predicted sugar kinase
|||||||||||||||-||||-|----|||||-----------|||||-||--|--|||||||||--  1 [S] COG0062 Uncharacterized conserved protein
||||||||||||||||||||-|----||||||--|||-----|||||-||--||||||||||||--  1 [G] COG0063 Predicted sugar kinase
||||--||||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0065 3-isopropylmalate dehydratase large subunit
|||---||||||-||-||||-|----||||||-|||||----||||||||||||||--||||||--  1 [E] COG0066 3-isopropylmalate dehydratase small subunit
|||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||--  1 [E] COG0067 Glutamate synthase domain 1
|||---||||------|-||----------|-----------|||-|---------|||-------  1 [O] COG0068 Hydrogenase maturation factor
|||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||--  1 [E] COG0069 Glutamate synthase domain 2
|||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||--  1 [E] COG0070 Glutamate synthase domain 3
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0072 Phenylalanyl-tRNA synthetase beta subunit
||||||--||||-||-||||-|----||||||-|||||----|||-||||||||||--||||||--  1 [E] COG0077 Prephenate dehydratase
|||||||||||||||-||||||----||||||--||||----||||||||||||||--||||||--  1 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0080 Ribosomal protein L11
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0081 Ribosomal protein L1
||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||--  1 [E] COG0082 Chorismate synthase
-|-|||||-||||||-||||-|----||||||-|||||----|||||||-|||---|||-------  1 [E] COG0083 Homoserine kinase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0087 Ribosomal protein L3
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0088 Ribosomal protein L4
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0089 Ribosomal protein L23
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0090 Ribosomal protein L2
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0091 Ribosomal protein L22
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0092 Ribosomal protein S3
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0093 Ribosomal protein L14
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0094 Ribosomal protein L5
---|||||---||||-||||--||--|----|||||||-||||||||-||----------------  1 [H] COG0095 Lipoate-protein ligase A
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0096 Ribosomal protein S8
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0097 Ribosomal protein L6P/L9E
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0098 Ribosomal protein S5
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0099 Ribosomal protein S13
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0100 Ribosomal protein S11
|||||||||||--||||||||||||||||||||||||||-||||||||||||||||||||||||||  1 [J] COG0101 Pseudouridylate synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0102 Ribosomal protein L13
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0103 Ribosomal protein S9
||||||||||||-||-||||||----||||||||||||----||||||||||||||||||||||--  1 [F] COG0104 Adenylosuccinate synthase
|||||||||||||||||-||-||||||||||--|||||----|||||-||||||||||||||||||  1 [F] COG0105 Nucleoside diphosphate kinase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0107 Imidazoleglycerol-phosphate synthase
||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase
---|||--|-|||||-|-||-|----||||----||||----||||||-|--|--|---|||||||  1 [O] COG0109 Polyprenyltransferase (cytochrome oxidase assembly factor)
||||||||||||||||||||-|||||||||||||||||-|||||||||||||||||||||||||||  1 [E] COG0112 Glycine/serine hydroxymethyltransferase
||||||--|||||||-|-||||||--|||||---||||----|||||-||-|||||||||||||||  1 [H] COG0113 Delta-aminolevulinic acid dehydratase
--||------|||||---|--|||--||||----||||----|||||-||||||||||||||||||  1 [C] COG0114 Fumarase
-|----|||||-|-----|-||--------||||||||----||||||||||||||----------  1 [L] COG0116 Predicted N6-adenine-specific DNA methylase
-------------||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG0117 Pyrimidine deaminase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0118 Glutamine amidotransferase
||||||||||||||||--||-|||||----||||||------||||||||||||||---|||||--  1 [G] COG0120 Ribose 5-phosphate isomerase
||--|-||--||-|----||-------||-------------|||||-||||-|||---||||---  1 [R] COG0121 Predicted glutamine amidotransferase
|-||--|||---||||--|--|-----||-|-----||-|--|||||-||--|--|---|||||--  1 [L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0124 Histidyl-tRNA synthetase
||||||||||||||||||||||||||||||-|||||||||||||||||||||||||||||||||||  1 [F] COG0125 Thymidylate kinase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||--  1 [G] COG0126 3-phosphoglycerate kinase
||||||||||||||||||||||||||||||||||||||----|||||-||||||||--||||||--  1 [F] COG0127 Xanthosine triphosphate pyrophosphatase
||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||--  1 [E] COG0128 5-enolpyruvylshikimate-3-phosphate synthase
||||||||||||||||||||||||||||||||||||||||--||||||||||||||--||||||||  1 [J] COG0130 Pseudouridine synthase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0131 Imidazoleglycerol-phosphate dehydratase
||||---|||---||-|||||||---||||||-|||||----||||||||||||||||||||||--  1 [E] COG0133 Tryptophan synthase beta chain
||||||-||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1 [E] COG0134 Indole-3-glycerol phosphate synthase
||||||-||||||||-||||-||---|---||-|||||----||||||||||||||||||||||--  1 [E] COG0135 Phosphoribosylanthranilate isomerase
||||||--||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0137 Argininosuccinate synthase
--||||--|----||-||||||----||||||-|||||----||||||||||||||--||||||--  1 [F] COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0139 Phosphoribosyl-AMP cyclohydrolase
||||-----|||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0140 Phosphoribosyl-ATP pyrophosphohydrolase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0141 Histidinol dehydrogenase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0143 Methionyl-tRNA synthetase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||--  1 [G] COG0148 Enolase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||--  1 [G] COG0149 Triosephosphate isomerase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0150 Phosphoribosylaminoimidazole (AIR) synthetase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||||||||||--  1 [F] COG0151 Phosphoribosylamine-glycine ligase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||||  1 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase
------|---|--||--|--|---|-|||-||-|--||----|||||-|-||--------------  1 [G] COG0153 Galactokinase
--------|-||-||-|-||-|----|||-|-----||----||||||||--||||---|||||--  1 [P] COG0155 Sulfite reductase, beta subunit (hemoprotein)
||||--||||||-|--|||||-----|||||-||-|||----|||||-||||||||||-||-||--  1 [H] COG0157 Nicotinate-nucleotide pyrophosphorylase
---|---------||---||----------------------|||||-||||-||||||-||-|--  1 [G] COG0158 Fructose-1,6-bisphosphatase
||||||-||||||||-||||-||---||||||-|||||----||||||||||||||||||||||--  1 [E] COG0159 Tryptophan synthase alpha chain
-|-----------||-|---||-|--|||||---|-||----||||||||||||||||||||||--  1 [H] COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0162 Tyrosyl-tRNA synthetase
|||-||||||||||--|-||-|||------------||----|||||-||-|-|||||||||-|||  1 [H] COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase
||||||||||||||||||||||||-|||||||||||||----|||||-||||||||||||||||||  1 [L] COG0164 Ribonuclease HII
||||||--||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0165 Argininosuccinate lyase
-|-|||----||||||||||||||||||||||||||||-|||||||||||||||||||||||||--  1 [G] COG0166 Glucose-6-phosphate isomerase
|||||||||||||||-||||||--||||||||||||||||||||||||||--||||||||||||--  1 [H] COG0171 NAD synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0172 Seryl-tRNA synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0173 Aspartyl-tRNA synthetase
||||||||||||||||||||||||||||||||||||||----||||||||||||||||||||||||  1 [L] COG0177 Predicted EndoIII-related endonuclease
|-||------------|||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG0178 Excinuclease ATPase subunit
|||||||||||||||---||-|----||||----||||----|||||-||-|-|||--||||||--  1 [Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0180 Tryptophanyl-tRNA synthetase
||||||--|||||||-|-||||||--|||||---||||----||||||||-|||||||||||||||  1 [H] COG0181 Porphobilinogen deaminase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0184 Ribosomal protein S15P/S13E
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0185 Ribosomal protein S19
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0186 Ribosomal protein S17
--||||----||-||-|||||||||||||||||||||||||||||||||||||-||||||||||||  1 [H] COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase
-------------||-||||||--||||||||||||||||||||||||||||||||||||||||--  1 [H] COG0192 S-adenosylmethionine synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0193 Peptidyl-tRNA hydrolase
-------------|||||||||||--||||||||||||||||||||||||||||||||||||||||  1 [F] COG0194 Guanylate kinase
|||||||||||||---||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0195 Transcription elongation factor
-------------||-|||||||||-||||||||||||||||||||||||||||||||||||||--  1 [H] COG0196 FAD synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0197 Ribosomal protein L16/L10E
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0198 Ribosomal protein L24
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0199 Ribosomal protein S14
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0200 Ribosomal protein L15
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0201 Preprotein translocase subunit SecY
||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0203 Ribosomal protein L17
-------------||||||||||||||||||||||||||||||||||||-|||------||-|---  1 [G] COG0205 6-phosphofructokinase
||||||||||------||||||--||||||||||||||-|||||||||||||||||||||||||||  1 [D] COG0206 Cell division GTPase
|||-----||---|||----||----||||||||||||-|||||||||||||||||---|||||--  1 [F] COG0207 Thymidylate synthase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0211 Ribosomal protein L27
|--|-----||||||-|-|||||||-||||||-|||||--|||||||-||||||||||||||||||  1 [H] COG0212 5-formyltetrahydrofolate cyclo-ligase
-||---|||--------|---|-----||-||-||||||||||||-|-|------|---||-|---  1 [F] COG0213 Thymidine phosphorylase
--|||||||-||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0215 Cysteinyl-tRNA synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0216 Protein chain release factor A
-|||--||||---|--||--|---------||||||||||||||||||||||||||||||||||||  1 [R] COG0218 Predicted GTPase
------------------||||||--|||||||||-|||||||||||-||||||||--||||||--  1 [J] COG0219 Predicted rRNA methylase (SpoU class)
-------------||||||||||||-||||||||||||||||||||||||||||||||||||||||  1 [R] COG0220 Predicted S-adenosylmethionine-dependent methyltransferase
|-||||||-|-||||||-||||||--|||||----|-|||||||||||||||||||||||||||||  1 [C] COG0221 Inorganic pyrophosphatase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0222 Ribosomal protein L7/L12
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0224 F0F1-type ATP synthase, gamma subunit
|-||-------|-||---||||--|-|||||||||||||||||||||-||||||||||||||||--  1 [O] COG0225 Peptide methionine sulfoxide reductase
||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||--  1 [P] COG0226 ABC-type phosphate transport system, periplasmic component
-------------||-|||||||||||||-|||||||||||||||||||||||||||||-||||||  1 [J] COG0227 Ribosomal protein L28
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0228 Ribosomal protein S16
|-||---------||---||||--|-|||-||||||||-||||||||-||||||||||||||||--  1 [O] COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase
-------------||-||||-||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0230 Ribosomal protein L34
------------------|--|----||||-----|------|||||-||||---|---|||||||  1 [F] COG0232 dGTP triphosphohydrolase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0233 Ribosome recycling factor
--|----------||-||||||||||||||||||||||--||||||||||||||||||||||||||  1 [O] COG0234 Co-chaperonin GroES (HSP10)
--|----------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [IQ] COG0236 Acyl carrier protein
||||||||||||||||||||||||||||||||||||||-|||||||||||||||||||||||||||  1 [H] COG0237 Dephospho-CoA kinase
-------------||-|||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0238 Ribosomal protein S18
-|||--||-|---||-||||-|----|||-|--|||||----|||||-||||||||||||||||--  1 [D] COG0239 Integral membrane protein possibly involved in chromosome condensation
|-------|----|||||||||||||||||||||||||||--|||||-||||||||||||||||||  1 [C] COG0240 Glycerol-3-phosphate dehydrogenase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0242 N-formylmethionyl-tRNA deformylase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0244 Ribosomal protein L10
----------------|||||||||-|||||----|||--||||||||||||||||||||||||--  1 [I] COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
--||-|-------|||||||||||||----|||-||||----||||||||||||||---|||||||  1 [L] COG0249 Mismatch repair ATPase (MutS family)
||------||------|||||-||--|||||---||||----||||||||||||||||||||||||  1 [E] COG0253 Diaminopimelate epimerase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0255 Ribosomal protein L29
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0256 Ribosomal protein L18
-------------||-||||-||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0257 Ribosomal protein L36
-------------||---||-|-----|||------------|||||-|||-||||---|||||--  1 [H] COG0259 Pyridoxamine-phosphate oxidase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0261 Ribosomal protein L21
--|----------|||-|--||||--||||||||||||||||||||||||||||||---|||||-|  1 [H] COG0262 Dihydrofolate reductase
--|----------||-||||-|--|-||||||||-|||----|||||-||||||||--||||||--  1 [E] COG0263 Glutamate 5-kinase
--------------|-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0264 Translation elongation factor Ts
-------------||-|||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0267 Ribosomal protein L33
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0268 Ribosomal protein S20
||----||-||||-|---||------|---|-||--||||--|||-|-|-|-||||||--|-||--  1 [L] COG0270 Site-specific DNA methylase
---|---------||---||----------------------||||||||||||||---|||||||  1 [T] COG0271 Stress-induced morphogen (activity unknown)
|--|||----|-|---||||-|--|-|||||||||||||||||||||-|-||-------||-|---  1 [F] COG0274 Deoxyribose-phosphate aldolase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [M] COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis
----||-------||-|-||-|||--||||-|-|||||----|||||-||||||||||||||||||  1 [H] COG0276 Protoheme ferro-lyase (ferrochelatase)
---|---------|||--||----------------------||||||||||||||---|||||||  1 [O] COG0278 Glutaredoxin-related protein
---------------||||||||||||||||||||||||||||||||-||||||||---|||||||  1 [F] COG0283 Cytidylate kinase
|||||||||||||||-||||||----||||||||||||----||||||||||||||||||||||--  1 [F] COG0284 Orotidine-5'-phosphate decarboxylase
---|||-------||-||||||--|-||||||||||||----||||||||||||||||||||||||  1 [H] COG0285 Folylpolyglutamate synthase
||||---||----------|-------||--|||||--|||-|||-|-|||||||||||-||-|-|  1 [V] COG0286 Type I restriction-modification system methyltransferase subunit
||||||--|||||||-||||-|----||||||-|||||----|||||-||||||||||||||||--  1 [E] COG0287 Prephenate dehydrogenase
|||-----||------||||--||--|||-||-|||||----||||||||||||||||||||||||  1 [E] COG0289 Dihydrodipicolinate reductase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0290 Translation initiation factor 3 (IF-3)
-------------|--||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0291 Ribosomal protein L35
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0292 Ribosomal protein L20
||||||--||---|||--------||----------------||||||||||||||---|||||||  1 [J] COG0293 23S rRNA methylase
|||||||||||||||-||||||||--||||||||||||----|||||-||||||||||||||||-|  1 [H] COG0294 Dihydropteroate synthase and related enzymes
---|------|-|||--|---|---|-||||||||||||||||||||-|-||-------||-||--  1 [F] COG0295 Cytidine deaminase
--|--------|-|--|-||||||--|||----|--|-----|||||-||||---|---||-|---  1 [G] COG0296 1,4-alpha-glucan branching enzyme
-|----||--||--|-||||||||------||-|--||----|||||-||||---|---||-|---  1 [G] COG0297 Glycogen synthase
--||||----|--||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN
|||||||||||||----|------|-----|||||||||||||||||-||||--------------  1 [H] COG0301 Thiamine biosynthesis ATP pyrophosphatase
----------||-||-|-||||----||||||||-|||----|||||-|||||--|||||||||||  1 [H] COG0302 GTP cyclohydrolase I
|||||||||||||---|-||-|----|||||---||||----|||||-||||---|||||||||--  1 [H] COG0303 Molybdopterin biosynthesis enzyme
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0305 Replicative DNA helicase
---|---------||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG0307 Riboflavin synthase alpha chain
--|-||----||-|||--||-|----||||-|||--------|||||-||||||||---|||||--  1 [E] COG0308 Aminopeptidase N
|||||||||||||---|-||----------|-----------|||-|---------|||-------  1 [O] COG0309 Hydrogenase maturation factor
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [R] COG0313 Predicted methyltransferases
|||||||||-|||---|-||-|----|||-----||||----|||||-||||---|||||||||--  1 [H] COG0314 Molybdopterin converting factor, large subunit
|||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||--  1 [H] COG0315 Molybdenum cofactor biosynthesis enzyme
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [R] COG0319 Predicted metal-dependent hydrolase
---|------|||||-|-||-|||--||||----|-||----||||||||||||||---|||||||  1 [H] COG0320 Lipoate synthase
----------|--||---||-|----||||------------||||||||||||||---|||||||  1 [H] COG0321 Lipoate-protein ligase B
--||---------|||||||||||||----||||||||----||||||||||||||---|||||||  1 [L] COG0323 DNA mismatch repair enzyme (predicted ATPase)
-------------||-||||||||||||||||||||||----||||||||||||||||||||||||  1 [J] COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase
--|----------||-||||||----||||||||||||----||||||||||||||||||||||--  1 [R] COG0325 Predicted enzyme with a TIM-barrel fold
-------------|||--|||---|||||||----|||----|||||||||||--||||-|-|-||  1 [O] COG0326 Molecular chaperone, HSP90 family
||||--||||---|||---|||||||||-|||||||||||--||||||||||-||||||-------  1 [S] COG0327 Uncharacterized conserved protein
---|------|--||---||-|--|-||||----||||----|||||-||||||||||||||||||  1 [L] COG0328 Ribonuclease HI
-------------||-||||||||--||||||||||||----|||||-||||||||||||||||||  1 [I] COG0331 (acyl-carrier-protein) S-malonyltransferase
----------------|-||||||---||-||||||||----|||||-||||||||||||||||||  1 [I] COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III
-------------||-||||||||||----||||||||||||||||||||||||||||||||||||  1 [J] COG0333 Ribosomal protein L32
--|||||||-|||||--|||||||--|---|--|||||----|||||--|||-|||||--||-|--  1 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0335 Ribosomal protein L19
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0336 tRNA-(guanine-N1)-methyltransferase
----||-|--|||||--|||||||--||||||||||||----||||||||||||||||||||||--  1 [E] COG0337 3-dehydroquinate synthetase
-|--|||-----------|||---|-----|----|-|----|||||-|-||||--||-------|  1 [L] COG0338 Site-specific DNA methylase
||||--|||--|-||-|||||||||-||||||||||||----|||||-||||||||||||||||||  1 [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase
||||--||-|------|||||||||||||||---||||-|--|||||-||||||||||||||||||  1 [U] COG0341 Preprotein translocase subunit SecF
||||--||-|------|||||||||||||||---||||-|--|||||-||||||||||||||||||  1 [U] COG0342 Preprotein translocase subunit SecD
|||||||||||||-||||||||||-||---||||||||----||||||||||||||||||||||||  1 [J] COG0343 Queuine/archaeosine tRNA-ribosyltransferase
----------------||||||--------|||||||||||||||||-||||-|||||||||||--  1 [S] COG0344 Predicted membrane protein
|-|-||----|||||-||||-|--|-||||||||||||----|||||-||||||||||||||||--  1 [E] COG0345 Pyrroline-5-carboxylate reductase
-------------|----||------|||||-----------|||||-|||||------|||||||  1 [J] COG0349 Ribonuclease D
|||||||||||||||-||-|||--|-||||||||||||----|||||-||||||||||||||||--  1 [H] COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase
--|-|||||----||-|-||||----||||||-|||||----|||||-||||||||||||||||--  1 [H] COG0352 Thiamine monophosphate synthase
----------------|-|||||||-||||||||||||||--|||||-||||||||||||||||||  1 [L] COG0353 Recombinational DNA repair protein (RecF pathway)
-------------||-|-||-|----||||------------||||||||||||||---|||||||  1 [R] COG0354 Predicted aminomethyltransferase related to GcvT
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0355 F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit)
--|----------|--|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0356 F0F1-type ATP synthase, subunit a
----------------||||||--|||||||||||||||||||||||-||||||||||||||||||  1 [M] COG0357 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division
|||||||||||||---||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0358 DNA primase (bacterial type)
--------------|-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0359 Ribosomal protein L9
-------------||-|||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0360 Ribosomal protein S6
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0361 Translation initiation factor 1 (IF-1)
-------------|||-|||--||||||||-|-||||-----|||||||-||-||----||||---  1 [G] COG0362 6-phosphogluconate dehydrogenase
-------------|||||||-||||||||--|-||||-----||||||||||||||||-|||||--  1 [G] COG0364 Glucose-6-phosphate 1-dehydrogenase
|||||||||||-||||----------||||||---|||----|||||-||--|-------|-|---  1 [E] COG0367 Asparagine synthase (glutamine-hydrolyzing)
|||||||||||||-----||||----|||-|----|-|----|||-|-||-----|---||||---  1 [H] COG0368 Cobalamin-5-phosphate synthase
-------------|||--||--||----------|-||----||||||||--|||----|-|-|--  1 [P] COG0369 Sulfite reductase, alpha subunit (flavoprotein)
|||---|||||-----||||-|--------||--||------|||||-||--|--||||----|--  1 [P] COG0370 Fe2+ transport system protein B
||||||--|||||---|-||||||--|||||---||||----|||||-||-||||||||-------  1 [H] COG0373 Glutamyl-tRNA reductase
--||----|----|----|--------||--------|----|||||-|---|--|---||-||--  1 [P] COG0376 Catalase (peroxidase I)
--|||||||-|||---||||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases
|||-----||----|-|-||||----|||-----|--||---|||||--||----||||||||---  1 [OK] COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase
||||--||||||----|||||-----|||||----|||----|||||-||--||||||-||-||--  1 [H] COG0379 Quinolinate synthase
|---||----|--|||--|-------||||------------|||-|--------|----|-|---  1 [G] COG0380 Trehalose-6-phosphate synthase
||-|--||---------|||-|--------||-||||-----|||||-||-|-|||--|-----||  1 [M] COG0381 UDP-N-acetylglucosamine 2-epimerase
|||||||||||||||-|-||-|||--|||||------|----|||||-||-|||||||||||||||  1 [H] COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases
-----||----|-||--|||-------||--|||-|-|----|-----------------------  1 [G] COG0383 Alpha-mannosidase
--||---------||---||||----|||-|----|||----|||-|-||-|---|---|||||--  1 [R] COG0384 Predicted epimerase, PhzC/PhzF homolog
--|----------|--|-||------|--|----|-||----|||||--|---|||---|||||--  1 [R] COG0385 Predicted Na+-dependent transporter
-------------|||--|-|-----|---|||||||||---|||||--|--||||-------|--  1 [O] COG0386 Glutathione peroxidase
-------------||---||-|----||||------|-----|||||------------||-|---  1 [P] COG0387 Ca2+/H+ antiporter
-||-------------||||-------||-----|-|-----|||-|--------|----------  1 [R] COG0390 ABC-type uncharacterized transport system, permease component
||||----||---|--||||-|----||||||||||||----|||||-|--|--------------  1 [S] COG0391 Uncharacterized conserved protein
||||--||||------||||------|||||---|||-|||||||-|--|--|--|---||||---  1 [S] COG0392 Predicted integral membrane protein
|||||||||--|-----|||-------|||-|---|-|----|||-|-|--|-----------|--  1 [S] COG0393 Uncharacterized conserved protein
|||||||||||||----|||-||||-||||||||||||----|||||-----|------|||||--  1 [O] COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
-------------||---||------|----------|----|||-|-||--|--|---||--|--  1 [S] COG0397 Uncharacterized conserved protein
-------------||---||-|||-------|--||||----|||----|--|------||||-||  1 [R] COG0400 Predicted esterase
-------------||---||----------------------|||-|--|---------|------  1 [S] COG0401 Uncharacterized homolog of Blt101
---|||||---||||-||||-|-----|||----||||----|||||--|--|-||---|||||--  1 [E] COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain
---|||||---||||-||||-|-----|||----||||----|||||--|--||||---|||||--  1 [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase)
----||----||||||--||||----|||-----|-||----|||-|-||--||||||-||-||--  1 [E] COG0405 Gamma-glutamyltransferase
--|-||-------||-|-||-|||--||||----||||----|||||-||-|||||||||||||||  1 [H] COG0407 Uroporphyrinogen-III decarboxylase
-------------||---||----------------------|||||-||--|--|---|||||||  1 [H] COG0408 Coproporphyrinogen III oxidase
|||---||||------|-||----------|-----------|||-|---------|||-------  1 [O] COG0409 Hydrogenase maturation factor
-|------|-|||----|||||----|------|---|----|||||--|-----|--|||||---  1 [E] COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
-|------|-|||----|||||-----------|--------|||||--|-----|--|||||---  1 [E] COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
---|--||--|||||-||||-|----|||||---||||----||||||||--||||||||||||--  1 [H] COG0413 Ketopantoate hydroxymethyltransferase
-------------||-||||-|----|||||---||||----||||||||--||||||||||||--  1 [H] COG0414 Panthothenate synthetase
|-||-------|-|----||------|-----|-||------||||||||----|----|--||--  1 [L] COG0415 Deoxyribodipyrimidine photolyase
----------------||||||||------|||||||||||||||||-||-|-|||||||||||--  1 [I] COG0416 Fatty acid/phospholipid biosynthesis enzyme
||||||||||||||||---|----------------------|||||-||----------------  1 [L] COG0417 DNA polymerase elongation subunit (family B)
-------------||---|-----------------------||||||||---||||||||-----  1 [F] COG0418 Dihydroorotase
||||||||||||||||||||||--||----||--|||-----|||||-||----------------  1 [L] COG0419 ATPase involved in DNA repair
||||||||||||||||||||||--||||||||--||||----|||||-||----------|-----  1 [L] COG0420 DNA repair exonuclease
-|--|||||||||||-||---|----|---|--|--||----||||||-|--||||||----|---  1 [E] COG0421 Spermidine synthase
||||---|||||----||||||----|||||-----||----|||||-||--||||--|||-||--  1 [H] COG0422 Thiamine biosynthesis protein ThiC
|||---|||-------|||||---------|-----------|||-|--|-----|----------  1 [C] COG0426 Uncharacterized flavoproteins
---|----|----||---|-|-----|---------------|||||--|---------|-|-|--  1 [C] COG0427 Acetyl-CoA hydrolase
||||--||--||||||||-|-|---||||------|------|||-|--|---|||--|-|-----  1 [P] COG0428 Predicted divalent heavy-metal cations transporter
-------------|-|--||----------------------|||||-||---|||----------  1 [R] COG0429 Predicted hydrolase of the alpha/beta-hydrolase fold
||||--|||||||||||--|----------------------|||-|--|-----|----------  1 [A] COG0430 RNA 3'-terminal phosphate cyclase
|||---|||||||-|-||||-|-----||-|-----||----|||-|-||---------||-----  1 [S] COG0432 Uncharacterized conserved protein
|||||||||||||---||||-|-----||---|----|----||||---|-|---|---|||||--  1 [R] COG0433 Predicted ATPase
-|-|--|||||-|-----||----------------------|---|------------|--|---  1 [R] COG0434 Predicted TIM-barrel enzyme
---|---------||---||------|---------------|||-|-||---------||||---  1 [O] COG0435 Predicted glutathione S-transferase
|||-----|--|-||-|-||-||||--||-||||||||----|||||-||||||||||||||||--  1 [I] COG0439 Biotin carboxylase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0441 Threonyl-tRNA synthetase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0442 Prolyl-tRNA synthetase
-------------||-||||||||||----||||||||||||||||||||||||||||||||||||  1 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division
---|----|---------||------||||-|--|||-----|||||-|-||--------------  1 [H] COG0447 Dihydroxynaphthoic acid synthase
-----------------|||||||--||||||-|--||----|||||-|-||-------||-|---  1 [G] COG0448 ADP-glucose pyrophosphorylase
||||||||-||||||||||||||||-||||||||||||----||||||||||||||||||||||--  1 [M] COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains
|||-|||||-|||||||||||||||--|||-||-||||----||||||||-||--|||||||||||  1 [O] COG0450 Peroxiredoxin
|||||||||||||||-||||||---|||||||||||||----|||||-||||||||||||||||--  1 [H] COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase
||||||--||||-||-||||||----||||||||||||----||||||||-|||||||||||||--  1 [EF] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
||||||||||||||||||||||||||||||||||||||--||||||||||||||||||||||||||  1 [O] COG0459 Chaperonin GroEL (HSP60 family)
|||||||||||||||-||||||-|--||||||||||||----||||||||||||||||||||||--  1 [F] COG0461 Orotate phosphoribosyltransferase
|||||||||||||||-||||||--||||||||||||||||||||||||||||||||||||||||-|  1 [FE] COG0462 Phosphoribosylpyrophosphate synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0465 ATP-dependent Zn proteases
--|----------||-||--||||||----|-----||||||||||||||||||||||||||||||  1 [O] COG0466 ATP-dependent Lon protease, bacterial type
|||||||||||||||||||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG0468 RecA/RadA recombinase
|||||||||||||||||||||||||-||||-|||||||||||||||||||||||||||||||||||  1 [L] COG0470 ATPase involved in DNA replication
|||-|--------||||-|||-----||||||||-||||||||||||--|----------|||---  1 [P] COG0474 Cation transport ATPase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0480 Translation elongation factors (GTPases)
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [M] COG0481 Membrane GTPase LepA
-------------||-||||||||-|||||||||||||||||||||||||||||||||||||||||  1 [J] COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain
||||--||||||||--||||-|---|||||-|||||||----|-||||||||||||--||||||||  1 [G] COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family
|-||||-------|||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain
-------------||-||||||||||----||||||||||||||||||||||||||||||||||||  1 [R] COG0486 Predicted GTPase
||||||||||||||-|||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0492 Thioredoxin reductase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0495 Leucyl-tRNA synthetase
||||----|||-||--||||-||||-----------------|||||-||||||||||||||||--  1 [R] COG0496 Predicted acid phosphatase
----------------|-||||--|-||||||||||||----|||||-||||||||||||||||||  1 [L] COG0497 ATPase involved in DNA repair
|||||||||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1 [E] COG0498 Threonine synthase
|||------|---||-|||||--|--|||||---|-||----||||||||||||||||||-|||--  1 [H] COG0502 Biotin synthase and related enzymes
||||||||||||||||||||-|||||||||||||||||||--||||||||||||||||||||||||  1 [F] COG0504 CTP synthase (UTP-ammonia lyase)
||||||--||||-||-||||||----||||||||||||----||||||||-|||||||||||||--  1 [EF] COG0505 Carbamoylphosphate synthase small subunit
---|---------||---||-|----|||-----|-||----|||||--|-|-|||||||||||--  1 [E] COG0506 Proline dehydrogenase
-|-----------||----|-|||-|-||-||||||||-|--|||||||||||||---|||||---  1 [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member
---|||||---||||-||||-|||---|||--|-||||-|--|||||-||--||||---|||||--  1 [E] COG0509 Glycine cleavage system H protein (lipoate-binding)
-------------||-----|---|------|||||||-||||||||-|-|-----------|---  1 [M] COG0510 Predicted choline kinase involved in LPS biosynthesis
|||---|||--|-||-|||||||||-||||||||||||----|||||-||||||||||||||||--  1 [I] COG0511 Biotin carboxyl carrier protein
--|---------||||--||||--|-|---||--||||----|||||-||||||||---||-||--  1 [L] COG0514 Superfamily II DNA helicase
|||||||||||||||-||||||-|-|||||||||||||----|||||-||||||||||||||||--  1 [F] COG0518 GMP synthase - Glutamine amidotransferase domain
|||||||||||||||-||||||-|-|||||||||||||----|||||-||||||||||||||||--  1 [F] COG0519 GMP synthase, PP-ATPase domain/subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0522 Ribosomal protein S4 and related proteins
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0525 Valyl-tRNA synthetase
|||||||||||||---||||||||||||||||||||||||||||||||||||||||||||||||||  1 [F] COG0528 Uridylate kinase
-------||---|||-|-|--|-----||-|-----||----||||||||--|--|--|-||||--  1 [P] COG0529 Adenylylsulfate kinase and related kinases
||||||||||||-||-|||-----||-----------|----|||||-|--|--------|-----  1 [P] COG0530 Ca2+/Na+ antiporter
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0532 Translation initiation factor 2 (IF-2; GTPase)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0533 Metal-dependent proteases with possible chaperone activity
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [R] COG0536 Predicted GTPase
|||||||||-|||||||-||||||-|||||||||||||||||||||||||||||||||||||||||  1 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
---|||--|-|||||-||||-|-----||--|--||||----|||||--|-|---|||-|||||--  1 [C] COG0538 Isocitrate dehydrogenases
-------------||-||||||||||||||||||||||-|--||||||||||||||||||||||||  1 [J] COG0539 Ribosomal protein S1
|||||||||||||||-||||||----||||||||||||----||||||||--||||||||||||--  1 [F] COG0540 Aspartate carbamoyltransferase, catalytic chain
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0541 Signal recognition particle GTPase
|||-||||||-|-||-||--|---|-|||-||-|-|||----|||||-||---|||---|----||  1 [HC] COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)
|-||--|||----|--|-||-|--|||||-|||||||||---|||||-||||||||||||||||--  1 [R] COG0546 Predicted phosphatases
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0552 Signal recognition particle GTPase
--||-||||--|||||-|||||||--|||-||||-|||--|||||||-|||||-------|-----  1 [KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family
---|||-||--|||--||||||---|||||||||||||-||||||||-|||||--|---|||||--  1 [C] COG0554 Glycerol kinase
||||||||||||------||-|-----||-|------|----|||||-||||||||---|||||--  1 [O] COG0555 ABC-type sulfate transport system, permease component
|-||------------|||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG0556 Helicase subunit of the DNA excision repair complex
---|---------||||||||||||-|---||||||||||||||||||||||||||||||||||--  1 [K] COG0557 Exoribonuclease R
-|------|-|||----|||||----|------|---|----|||||--|-----|--|||||---  1 [E] COG0559 Branched-chain amino acid ABC-type transport system, permease components
|--------------------|----|||||---------|||---|-----------||------  1 [M] COG0562 UDP-galactopyranose mutase
--||--|||----|||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [F] COG0563 Adenylate kinase and related kinases
-------------||------|||--||||----|-||----||||||||||||||---|||||||  1 [C] COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes
||||--|||||-|---||||||--||-||---||||||-||||||||-||||-||---||||----  1 [P] COG0569 K+ transport systems, NAD-binding component
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0571 dsRNA-specific ribonuclease
---|---------||--|||-|-|||----|||||||||-|||||||-|-||--------------  1 [F] COG0572 Uridine kinase
||||---||||||---||||-|---||||||||||||||-|||||||-|-|||--|--||||||--  1 [P] COG0573 ABC-type phosphate transport system, permease component
|||||||||||||---||||||--|-|||||--|-||-----|||||-||--||||||||||||||  1 [G] COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase
|||||||||||||||||||||||||||||||||||||||||||||||-||||||||||||||||||  1 [I] COG0575 CDP-diglyceride synthetase
|-||||-------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0576 Molecular chaperone GrpE (heat shock protein)
||||----||||-----||||||||-|||-||||||||----|||||-||-|-|||--||||||--  1 [V] COG0577 ABC-type antimicrobial peptide transport system, permease component
||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||--  1 [P] COG0581 ABC-type phosphate transport system, permease component
|||||||||||||||||----|--------------------|||||-||||----|||-------  1 [S] COG0585 Uncharacterized conserved protein
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0587 DNA polymerase III, alpha subunit
--|----------||-----|-||||||||||||||------||||||--||||||----||||--  1 [G] COG0588 Phosphoglycerate mutase 1
--|----------||||-||-|||--||||||-|||||----||||||||||||||---|||||||  1 [FJ] COG0590 Cytosine/adenosine deaminases
|-|||||||--||||---|-|--|--|------||-||----|||||-||||-||||||||||-||  1 [ER] COG0591 Na+/proline symporter
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)
-----------------||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0594 RNase P protein component
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [MU] COG0597 Lipoprotein signal peptidase
|||||||||||||---|-||----------|---|-||----|||||-||||||||||||||||||  1 [R] COG0603 Predicted PP-loop superfamily ATPase
|--------|------||||||---||||-|-----------|||||-||||||||||||||||-|  1 [O] COG0606 Predicted ATPase with chaperone activity
||||||||||||----|||||||||||---||||||||----|||||-||||||||||||||||||  1 [L] COG0608 Single-stranded DNA-specific exonuclease
|||||||||||||---|-||------||||------||----||||||||||||||--|----|--  1 [H] COG0611 Thiamine monophosphate kinase
||||----|--||---||||-|--------|------|----|||||-||||-|||----------  1 [R] COG0613 Predicted metal-dependent phosphoesterases (PHP family)
|||||||||||||||-||-----|--||||-|-|||||----||||||||||||||--||--||--  1 [E] COG0620 Methionine synthase II (cobalamin-independent)
||||--|||||||||--|--|---|----|||||||||-||||||||-||----------------  1 [R] COG0622 Predicted phosphoesterase
----------------|-||-|||---|||-|--||||----|||-||-|||-|||||||||||||  1 [I] COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH)
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0629 Single-stranded DNA-binding protein
-----------------||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG0632 Holliday junction resolvasome, DNA-binding subunit
----------------||--||----||||||-|||||||||||||||||||||||---|||||--  1 [F] COG0634 Hypoxanthine-guanine phosphoribosyltransferase
||||||||||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [C] COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K
--||--|||--------|||-|--||----|----|||----|||||-||--|--||||||-||--  1 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases
-----------------|||||----|||||---||||----|||||-||-----|---|||||--  1 [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain
---|--|||--||||-||--|-----|||--|||||||----|||||--|--------||||||||  1 [G] COG0647 Predicted sugar phosphatases of the HAD superfamily
||||||||--||||||||----||---||||---|||||||||||||||-----------------  1 [L] COG0648 Endonuclease IV
--|||||||-|||---||||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase)
|||-----||-|-||-|---||-----||||--|||||----||-||-||--|--|---|||-|-|  1 [R] COG0655 Multimeric flavodoxin WrbA
--|--|--|--|-||--|||-|--|-|||||||-||-|----|||||-||--|--|---||-||--  1 [I] COG0657 Esterase/lipase
----------------|||||||||||||-|||||||||||||||||-||||||||||||||||-|  1 [R] COG0658 Predicted membrane metal-binding protein
--|----------||||-||--||--||||-|---|||----|||-|-||-|---|||-||-|---  1 [P] COG0659 Sulfate permease and related transporters (MFS superfamily)
|-||||-----|-||---||-------||||------|----|||||-||-|||||---|||||||  1 [R] COG0661 Predicted unusual protein kinase
|||---||||------|||||------||-------||----|||||-||--||||||-|||||--  1 [G] COG0662 Mannose-6-phosphate isomerase
----------------||||||--||||||||||||||-|--||||||||||||||||||||||--  1 [H] COG0669 Phosphopantetheine adenylyltransferase
--------|---|||--||||---|---------|||-----||||---|-|-||---|--|--||  1 [P] COG0672 High-affinity Fe2+/Pb2+ permease
|||||||||||||||-|||||---|--||-||--||-|----|||||-|-------|||-------  1 [C] COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit
-|||||||-|||----||||-|---|-||-------------|||-|-----|---||--------  1 [L] COG0675 Transposase and inactivated derivatives
-------------|------------|---------------|||||-|||||-------------  1 [G] COG0676 Uncharacterized enzymes related to aldose 1-epimerase
||----||--|------|------------|---|-------|||||-||-||--|---||-|---  1 [M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase
||-------|---||-|||||-----|---||--||||----||||--||-||--|--||||||||  1 [R] COG0679 Predicted permeases
||||||||||||||||||||||||||||||||||||||-|--||||||||||||||||||||||||  1 [U] COG0681 Signal peptidase I
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [M] COG0682 Prolipoprotein diacylglyceryltransferase
|||-----||---|-------|----||||-------|----|||||-||||---|---||-|---  1 [H] COG0684 Demethylmenaquinone methyltransferase
--|-||||--|||||-||||-|----|---||-|||||----||||||||||||||--||||||--  1 [E] COG0685 5,10-methylenetetrahydrofolate reductase
||||----||---||-----||||---||||-----||----|||||-|||||||||||||||-||  1 [I] COG0688 Phosphatidylserine decarboxylase
|---|||||||||||||--|||----||||-----|||----|||||-||||||||---|||||||  1 [J] COG0689 RNase PH
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0690 Preprotein translocase subunit SecE
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0691 tmRNA-binding protein
-------------|||----||||-|||||-||||||||||||||||||||||||||||||-----  1 [L] COG0692 Uracil DNA glycosylase
---|----|----||---||--||----------||||----|||||||||||---||||||||||  1 [O] COG0694 Thioredoxin-like proteins and domains
--||-----------|--||----------|---|||||||||||||-||------||||------  1 [G] COG0696 Phosphoglyceromutase
----------------|||-|-----|||||-|||||||||||--||----|----|||-|||-||  1 [G] COG0698 Ribose 5-phosphate isomerase RpiB
-------------|||--||-|-----||-----|-||----|||----|-----||||-------  1 [R] COG0699 Predicted GTPases (dynamin-related)
------------------|-----------|-----||----|||-|-||-----|----------  1 [S] COG0700 Uncharacterized membrane protein
|||-----||------||||-------||-|-||-|||----|||-------------|-------  1 [R] COG0701 Predicted permeases
|||||||||||||---||||-|---|||||||||||-||-|||||||-||--|--|---|||||--  1 [P] COG0704 Phosphate uptake regulator
-||||-|||||||||-||||-|--|-||||||||||||----|||||-|||||--|--||||||--  1 [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid)
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0706 Preprotein translocase subunit YidC
--|------|-|----||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase
|-|-||--|--|-|||--||||--|||||-||||-||-----|||||-||||||||||||||||||  1 [L] COG0708 Exonuclease III
-|-------|||----|-------------------------|||||--|||------|-|-----  1 [E] COG0709 Selenophosphate synthase
||||||-|||||-||-|-----||-------||||||-----|||-|------||-----------  1 [E] COG0710 3-dehydroquinate dehydratase
--|-------------|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0711 F0F1-type ATP synthase, subunit b
-------------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0712 F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)
--||||------|---|-||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)
-||-----||---||--|||||||--|---|--||-||----||||--||||---|---|||||--  1 [P] COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components
|||||||||||||---|-||--||--|||||------|----||||||-|||||||||||||||||  1 [F] COG0717 Deoxycytidine deaminase
-----------------|||||||-|||||||||||||||||||||||||||||||||||||||||  1 [S] COG0718 Uncharacterized protein conserved in bacteria
||||||||||||----||||----------|---|-||----|||||-||||||||||||||||||  1 [H] COG0720 6-pyruvoyl-tetrahydropterin synthase
|||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||--  1 [P] COG0725 ABC-type molybdate transport system, periplasmic component
-|||--|||-||------||-|---------||---------|||||-||--|--||||-|-|---  1 [R] COG0727 Predicted Fe-S-cluster oxidoreductase
----------------|||||||||||||||-----------||||||||||||||||||||||||  1 [R] COG0728 Uncharacterized membrane protein, putative virulence factor
----------------|---|---------------------|||||-||||||||---|||||--  1 [M] COG0729 Outer membrane protein
|||||||||||||---||||||----|--|||--||||----|||||-||||||||||||||||--  1 [R] COG0730 Predicted permeases
||||-|-||----------|-------||--|||||--|||||||-|-|||||---|||-||-|-|  1 [V] COG0732 Restriction endonuclease S subunits
-------------||-||--|||||||||||||||||||||||||||||----|||||||||||||  1 [I] COG0736 Phosphopantetheinyl transferase (holo-ACP synthase)
-------------|----------------------|-----|||-|---|-|||-|||--|-|--  1 [G] COG0738 Fucose permease
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1 [OU] COG0740 Protease subunit of ATP-dependent Clp proteases
-----------------|||||||||||||||||||||-|--||||||||||||||||||||||||  1 [L] COG0742 N6-adenine-specific methylase
----------------|||||||||-|||||----|||----|||||||||||||||||||--|--  1 [I] COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase
|||||||||||||---|-||-|----|||-----||||----|||||-||||--||||||||||--  1 [H] COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A
-------------|--||||||||||||||||||||||----|||||-||||||||||||||||||  1 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains
|||||||||||||---||||||||||||||||||||||----|||||-||||||||||||||||||  1 [M] COG0750 Predicted membrane-associated Zn-dependent proteases 1
----------------|||||-||-------|||-|||----||||||||||||||||||||||||  1 [J] COG0751 Glycyl-tRNA synthetase, beta subunit
----------------|||||-||-------|||-|||----||||||||||||||||||||||||  1 [J] COG0752 Glycyl-tRNA synthetase, alpha subunit
-------------||------|----|-------||||----|||||-||||-||||||||||---  1 [P] COG0753 Catalase
--|-----|-|-|---|-||-|----||||----|-||----|||||-||||||||||||||||||  1 [O] COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component
-------------||||---|-|||-||||||||-||-----||||||-|||||||||-|||||||  1 [F] COG0756 dUTPase
----------------||||||--|||||-|-||||||||--|||||-||||||||||||||||-|  1 [LU] COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake
----------------||||||||||-||-||||||||----|---|-|||||||||||||||||-  1 [S] COG0759 Uncharacterized conserved protein
----------------|||||||||-|||||-----||----||||||||||||||||||||||--  1 [IM] COG0761 Penicillin tolerance protein
-----------------||||-||||||||||||||||----|||||-||||---||||||-||--  1 [S] COG0762 Predicted integral membrane protein
----------------|-|||-||------------------|||||-||||||||||||||||||  1 [M] COG0763 Lipid A disaccharide synthetase
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase
----------------|-||-------|||------------|||||-||||||||||||||||||  1 [Q] COG0767 ABC-type transport system involved in resistance to organic solvents, permease component
|--------|------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0769 UDP-N-acetylmuramyl tripeptide synthase
|||------|------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase
|--------|------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase
----------------|-|||-||------------------|||||-||||||||||||||||||  1 [M] COG0774 UDP-3-O-acyl-N-acetylglucosamine deacetylase
----------------|-||||||--|||-||||||||----|||||-||||||||||||||||--  1 [I] COG0777 Acetyl-CoA carboxylase beta subunit
----------------||||||--|||||-||||||||----|||||-||||||||||||||||||  1 [S] COG0779 Uncharacterized protein conserved in bacteria
----------|-|---||||-------------||-||----|||||-||||||||||||||||||  1 [R] COG0780 Enzyme related to GTP cyclohydrolase I
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0781 Transcription termination factor
---|--------------||||--|||----|||||||-|--|||||-|||||--|||||-|-|||  1 [P] COG0783 DNA-binding ferritin-like protein (oxidative damage protectant)
------------------|-|-----|-------|-------|||||-|||--||-||--------  1 [E] COG0786 Na+/glutamate symporter
---|------------|-||-|----|||-------||----|||-|-|||||--|||||||-|--  1 [F] COG0788 Formyltetrahydrofolate hydrolase
----------------||||||--|-|||||-----------|||||-||||||||||||||||--  1 [L] COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase
----||----||----||||||||||----|---||||----|||||-||||||||||||||||||  1 [M] COG0793 Periplasmic protease
----------------|-||||--||||||||||||||----||||||||||-|||||||||||--  1 [M] COG0796 Glutamate racemase
----------------|-||----||----|-----------|||||-||||||||||||||||||  1 [M] COG0797 Lipoproteins
----------------||||-|||||||||-|||||||----|||||-||||||||||||||||||  1 [S] COG0799 Uncharacterized homolog of plant Iojap protein
-------------||-||||||||--||||||||||||----|||||-||||||||||||||||-|  1 [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase
----------------||||||||||||||||||||||-|--|||||-||||||||||||||||||  1 [R] COG0802 Predicted ATPase or kinase
--||||--|-|||---|-||-|----||||----||||----|||||-||||||||||||||||||  1 [U] COG0805 Sec-independent protein secretion pathway component TatC
----------------||||||--||||||||||||||----||||||||||||||||||||||||  1 [J] COG0806 RimM protein, required for 16S rRNA processing
----||--|----||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG0807 GTP cyclohydrolase II
----------------||||||---|----||||||||----||||||||||||||||||||||||  1 [J] COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)
----------------|--||---------------------|||||-||||||||||||||||--  1 [M] COG0810 Periplasmic protein TonB, links inner and outer membranes
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0812 UDP-N-acetylmuramate dehydrogenase
-----------|--------||--|------||||||-|||||||||||-||----||----|---  1 [F] COG0813 Purine-nucleoside phosphorylase
----------------||||-|||||||||------------|||||-||||-|||||||||||||  1 [M] COG0815 Apolipoprotein N-acyltransferase
----------------||||||||--|||||||-||||||||||||||||||||||||||||||||  1 [L] COG0816 Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis)
-----------------||||||||-||||------------|||||-||||||||||||||||||  1 [L] COG0817 Holliday junction resolvasome, endonuclease subunit
-----------------|||-|--------||||||||----|||||-|||||||||||||||---  1 [M] COG0818 Diacylglycerol kinase
----------------||||||--|-|||-|||||||||---||||||||||||||||||||||--  1 [R] COG0820 Predicted Fe-S-cluster redox enzyme
----------------|||||||||-|||||-----||----||||||||||||||||||||||--  1 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis
--||----|----|||||-||-||||||||||||||||||||||||||||||-|||||||||||||  1 [C] COG0822 NifU homolog involved in Fe-S cluster formation
--|-----|---------||--||------------------|||||-|||||--|||||||||||  1 [U] COG0823 Periplasmic component of the Tol biopolymer transport system
----------------|-||||||--|||-||||||||----|||||-||||||||||||||||--  1 [I] COG0825 Acetyl-CoA carboxylase alpha subunit
----------------|-||--||||----|||||||||-||||||||||||||||||||||||||  1 [J] COG0828 Ribosomal protein S21
--||--|||--------|||----||----|----|||----|||||-||--|--||||||-||--  1 [NT] COG0835 Chemotaxis signal transduction protein
--||--|||-------||||-|--------|-----------|||||-||--|---||-|||||-|  1 [M] COG0836 Mannose-1-phosphate guanylyltransferase
------------------||----------------------|||||--|--||||||-|||||--  1 [G] COG0837 Glucokinase
--||||--|-|||---|-||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A)
--||||--|--||---|-||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J)
---|------||||--|-||-|----||||----||||----||||||-|--|--|---|||||||  1 [C] COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1
------||||||||||||--||----|||||-|-||||-|--|||||-||-|---||||----|--  1 [K] COG0846 NAD-dependent protein deacetylases, SIR2 family
---------|------||--||--||----||||||||----||||||||||||||||||||||||  1 [D] COG0849 Actin-like ATPase involved in cell division
----------------||||||--------|----|||----||||||||-|||||||-||||---  1 [D] COG0850 Septum formation inhibitor
------------------||||--------------------||||||||--||||||-||||---  1 [D] COG0851 Septum formation topological specificity factor
--|||||||-|||---||||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit
----------------||||-|----|||||---||||----|||||--|--||||||||--||--  1 [H] COG0853 Aspartate 1-decarboxylase
----------------|-||----------------------|||||-||--||||||||||||--  1 [H] COG0854 Pyridoxal phosphate biosynthesis protein
--|---------------||-|-----||||------|----|||||-||--||||||||||||--  1 [P] COG0855 Polyphosphate kinase
---|----|---------||-|-----||-------------||||||||||-||-|||-------  1 [R] COG0857 BioD-like N-terminal domain of phosphotransacetylase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0858 Ribosome-binding factor A
-|-||||----------|-|||----------|--|-|----|||||-|-|-||-|||-|||||--  1 [L] COG0863 DNA modification methylase
||||--|||||||-----------------|----|||----|||-|---------||---|-|--  1 [K] COG0864 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain
|||-----||-----------|---|----|----|||----|||--------------||||---  1 [F] COG1001 Adenine deaminase
---|||||---||||-||||-|-----|||----||||----|||||--|--|-||---|||||--  1 [E] COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain
-|||---||--|----|-||------|||---|---||----|||||-||-||--|--||||||||  1 [M] COG1004 Predicted UDP-glucose 6-dehydrogenase
--||||--|-|||---|-||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H)
--||||--|-|||---|-||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N)
--||||----------|-||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M)
|||||||||||||||-|||||---|--||-||--||-|----|||||-|-------|||-------  1 [C] COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit
|||||||||||||---|||||---|--||-||--||-|----|||||-|------||||---||--  1 [C] COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit
-------------||-|----|----|-------|-||----|||||-||--|--|--|-|-----  1 [C] COG1017 Hemoglobin-like flavoprotein
-------------||----|------||||-||||||-----|||||-||-----|--||-||---  1 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins
---------------------------||-------|-----|||||-||-----------|----  1 [Q] COG1021 Peptide arylation enzymes
-------------|||------||------------------|||||-||----------------  1 [O] COG1025 Secreted/periplasmic Zn-dependent peptidases, insulinase-like
----||-----------|-|------|---|-----||----|||||-||||-||-||||-|----  1 [E] COG1027 Aspartate ammonia-lyase
|||-|||||||||----|||||-----||-||-----|----|||-|-||------------|---  1 [C] COG1032 Fe-S oxidoreductase
----------------||||-|-----||-|-----------||||||-|--||||||||||||||  1 [C] COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)
----------------||||||--||-||-||||||||----|||||-||||||||||||||||-|  1 [R] COG1040 Predicted amidophosphoribosyltransferases
-|||||||||||-------|----------------------|||||-||---||-----|-|---  1 [C] COG1042 Acyl-CoA synthetase (NDP forming)
----------------|-|||-||------------------|||||-||||||||||||||||||  1 [M] COG1043 Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase
----------------|-|||-||------------------|||||-||||||||||||||||||  1 [M] COG1044 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase
------------------||----------------------|||||-||-|||||||||------  1 [C] COG1049 Aconitase B
------------------||-|||--|----||||||-----||||||||--|--|---|||||||  1 [R] COG1054 Predicted sulfurtransferase
|||||||||-|||-----|--|-----||--|----------|||||---||---|----------  1 [H] COG1056 Nicotinamide mononucleotide adenylyltransferase
-------------||-|||||---||||||||||||||||||||||||||--||||||||||||--  1 [H] COG1057 Nicotinic acid mononucleotide adenylyltransferase
---||||||-||||---|||||-----||||-||||||----|||||-|----|||---|||||--  1 [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA
||||||--|||-|---||||||||---||||------|----|||||-|-------|||-------  1 [HR] COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes
--|||||||-||||||---|||--|-|||||-||||------|||||-|-----------------  1 [KL] COG1061 DNA or RNA helicases of superfamily II
-----------|-||---||------||||-------|----|||||--||--|||---|||||--  1 [C] COG1062 Zn-dependent alcohol dehydrogenases, class III
----------------|||||||||-|||-|||-||||----|||||-||||||||||||||||||  1 [O] COG1066 Predicted ATP-dependent serine protease
||||||||||-------|------|-----|-----||----|||||-||||--------------  1 [O] COG1067 Predicted ATP-dependent protease
-------------|--------------------|-||----|||||------------||||---  1 [C] COG1069 Ribulose kinase
--------------------|-||||-||-||||||||----||||||||||||||||||||||||  1 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)
|---||--||------||-||-||||----|----|||----|||||-|||||--||||----|||  1 [D] COG1077 Actin-like ATPase involved in cell morphogenesis
--|---|-|-|--||--|--------||--||----------|||||-|-||--------------  1 [C] COG1085 Galactose-1-phosphate uridylyltransferase
|------------||-|-||||----|---||-|-|||--|||||||-||||-|||||||||||--  1 [M] COG1087 UDP-glucose 4-epimerase
|-|-----|-------|-||-------||-|-----------|||-|-||--|---||-|-|||--  1 [M] COG1089 GDP-D-mannose dehydratase
----||------------||------||||----||||----|||||--||||-------------  1 [R] COG1090 Predicted nucleoside-diphosphate sugar epimerase
|-||-||||--||---|-||||----|||||||---||----|---|--|--||||---||-||||  1 [M] COG1091 dTDP-4-dehydrorhamnose reductase
--|-----|----||||||||||||-||||||||||||----||||||||||-|||||||||||||  1 [E] COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes
|-||--|||-|-|---|||||||||-||-|||||||||----||||||||||-||---|||||-||  1 [P] COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components
|||||-||||-|-||||||-|------||||---|---|||||||-|--|--|---|--------|  1 [L] COG1112 Superfamily I DNA and RNA helicases and helicase subunits
--------------------|-|||-|---|-|||-|-----|||||-||||--------------  1 [E] COG1114 Branched-chain amino acid permeases
--|---||------------|||||-|-----|||-||----|||-|-||||-||-|||-||----  1 [E] COG1115 Na+/alanine symporter
-||-||--||||-----|||||||--|---|--||-||----||||---||||--|---|||||--  1 [P] COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component
||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||--  1 [P] COG1117 ABC-type phosphate transport system, ATPase component
------------------||-------||--------|----|||||-||--||||||||||||--  1 [P] COG1118 ABC-type sulfate/molybdate transport systems, ATPase component
--|----------||------|----||||-|--||||----|||||----|--------------  1 [P] COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA
|-||--|||-|||---|||||||||-|--|||||||||----||||||||||-||---|||||-||  1 [P] COG1121 ABC-type Mn/Zn transport systems, ATPase component
|||-|----|-|------|||-----||||----|-------|||||-|------|||-||-|---  1 [R] COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase
--------|----------|||-----||-|||||||-----|||||--|------||-||||---  1 [E] COG1125 ABC-type proline/glycine betaine transport systems, ATPase components
----------------|-||-------|||------------|||||-||||||||||||||||||  1 [Q] COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component
------------------------------------------|||-|-----------|||||---  1 [I] COG1133 ABC-type long-chain fatty acid transport system, fused permease and ATPase components
------------------||||-||-|---||||||||----|||||-||||||||||||||||--  1 [P] COG1135 ABC-type metal ion transport system, ATPase component
----------------||||||||||----------------|||||-||||||||||||||||||  1 [R] COG1137 ABC-type (unclassified) transport system, ATPase component
|--|||--|-|||-------||---------|----||----|||------|-||||||-------  1 [C] COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain
||||||-|||||-----|||-|----|||||-----------|||-|-||--|--|||||||||||  1 [C] COG1146 Ferredoxin
|||----|||-------|--|---------|-----------|||||-------------------  1 [C] COG1151 6Fe-6S prismane cluster-containing protein
----------------|||||||||-||||||---|||----||||||||||||||||||||||--  1 [HI] COG1154 Deoxyxylulose-5-phosphate synthase
----------------||----||||----|----|||----||||||||-----|||||||||--  1 [NU] COG1157 Flagellar biosynthesis/type III secretory pathway ATPase
----------------||--|||||||||||---||||----||||||||||||||||||||||||  1 [K] COG1158 Transcription termination factor
----------------||||||--||||||||||||||||||||||||||||||||||||||||||  1 [R] COG1159 GTPase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [R] COG1160 Predicted GTPases
--|-------------|||||----||||||||||||||||||||||-||||||||------|---  1 [R] COG1162 Predicted GTPases
---|--------------||------||||-|--|||-----|||||-|-||--------------  1 [H] COG1165 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
------------------||-|--------------------|||||-||-||||-|||-------  1 [E] COG1166 Arginine decarboxylase (spermidine biosynthesis)
--------------------||----||||||-|-|||----|||||---|----|----------  1 [E] COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
-------------||-----|---------|---|-||----|||||-|||||||||||-------  1 [H] COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
-------------------|----------||--||||-||||||||--||----|---||-|---  1 [I] COG1182 Acyl carrier protein phosphodiesterase
-------------||-||||||||||||||||||||||----||||||||||||||||||||||||  1 [J] COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)
-----------------|--|-----|---||||||||----|||||-||||-|||||||||||--  1 [J] COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
----------------||||--|||--||-|---||||----|||||-||-----||||-------  1 [K] COG1191 DNA-directed RNA polymerase specialized sigma subunit
||-|-|||-|||----|-||-||||||||||----|||--|||||||-||--||||||||||||||  1 [D] COG1192 ATPases involved in chromosome partitioning
|--|------|-|-|------||||-||||||||||||----||||||||||||||||||||||--  1 [L] COG1194 A/G-specific DNA glycosylase
----------|-------|||||-|-||||||||||||----|||||-|||||------|||||||  1 [L] COG1195 Recombinational DNA repair ATPase (RecF pathway)
-----------------|||||||||||||||||||||----||||||||||||||||||||||||  1 [LK] COG1197 Transcription-repair coupling factor (superfamily II helicase)
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1 [L] COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase
----------------||||||--||||||||||||||----|||||-||||||||||||||||||  1 [LK] COG1200 RecG-like helicase
|||||||||||||------|------|||-------------|||----|-----|---|||||--  1 [R] COG1201 Lhr-like helicases
|||---|||-|||---||--|-----------|----|----|||||----|--------------  1 [R] COG1203 Predicted helicases
|||||||||||||||||-------------------------|----------------||-----  1 [R] COG1204 Superfamily II helicase
----------------||||||----||||||||||||----||||||||||||||||||||||||  1 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)
------|---------|||||||||-|||||--|||||--||||||||||||||||||||||||--  1 [I] COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase
----------------|---|-||------------------|||||-||||||||||||||||||  1 [M] COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone
|-|--||||---|-----||-|----|||||-----------|---|--||-|--|---||-||--  1 [R] COG1216 Predicted glycosyltransferases
------------------||||----||||||||||||----||||||||||||||||||||||||  1 [T] COG1217 Predicted membrane GTPase involved in stress response
-------------||-|-||--||--||||------------|||||||||||-----||||||||  1 [P] COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase
-------------|--||||||||||||||||||||||----||||||||||||||||||||||||  1 [O] COG1219 ATP-dependent protease Clp, ATPase subunit
----------------||-------|--------||||----|||||||||||--|||||||||||  1 [O] COG1220 ATP-dependent protease HslVU (ClpYQ), ATPase subunit
--||||----|||||-||||-|----|||||---|-||----|||||-||||||||||||||||-|  1 [O] COG1225 Peroxiredoxin
--|---|---||-|||||-|-|----|--||||||||-----|||||--|-|||||--||||||--  1 [P] COG1230 Co/Zn/Cd efflux system component
||||||||||||||||-|||-|||||||||||||||||----|||-|----|---|------||--  1 [R] COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
||||||||||----|-|-|||-||||----||||||||----||||---|-----|---|||||||  1 [R] COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
-||------|------|-------------------------|||||-||||||||--||||||||  1 [S] COG1238 Predicted membrane protein
-|-------|------||--|---------|||-||||----|||||-|-----------------  1 [R] COG1242 Predicted Fe-S oxidoreductase
--||------------|----|-----|||------||----||||||||-|-|||----------  1 [E] COG1246 N-acetylglutamate synthase and related acetyltransferases
--|-------|-|-----||-|----|---||-|||||----|||-|-||-----|---|||||--  1 [M] COG1247 Sortase and related acyltransferases
--|-------------|----------||-|---|-||----|||||--|-----|---||-||--  1 [C] COG1251 NAD(P)H-nitrite reductase
---|-------|-||---||-|----||||-|--||||----|||||-|||----|---||||---  1 [C] COG1252 NADH dehydrogenase, FAD-containing subunit
-||-|||||-|||----|-|-|---|--|-||||||||----|||||-||-|---|----|-|---  1 [C] COG1254 Acylphosphatases
----------------||------||----|----|||----||||||||-----|||||||||--  1 [N] COG1256 Flagellar hook-associated protein
----------------||------------------------||||||||-----|||||||||--  1 [NO] COG1261 Flagellar basal body P-ring biosynthesis protein
|||---||-||-|---|---|-----------|--|||----|||||-||||-||||||-----||  1 [I] COG1267 Phosphatidylglycerophosphatase A and related proteins
-------------|||----||--|||||-||||||||----|||||-||--|||----|||||--  1 [R] COG1272 Predicted membrane protein, hemolysin III homolog
-|--|-|||----||-----------|||--||||-------|||-|-|-||-|------------  1 [P] COG1275 Tellurite resistance protein and related permeases
----------------|----|-------------|||----|||||--------|----|-|---  1 [P] COG1276 Putative copper export protein
--------------------|-----|||-|---|-||----|||||-||-|---|||-|-|---|  1 [R] COG1279 Lysine efflux permease
----------------||||||--------||||||||-|--|||||-||||||||---|||||--  1 [O] COG1281 Disulfide bond chaperones of the HSP33 family
------------------||-------|||------------|||||-||||-|||---|||||||  1 [C] COG1282 NAD/NADP transhydrogenase beta subunit
--------------------|---|-|-----||||||-|--|||-|-||--------|||||---  1 [P] COG1283 Na+/phosphate symporter
----------------|-||||--|--||-||-|-|||----|||||--|||---|---|||----  1 [S] COG1285 Uncharacterized membrane protein
------------------------||-----|||||||----|||||-||||||||||||||||||  1 [R] COG1286 Uncharacterized membrane protein, required for colicin V production
--------------------|----|------|||-||----|||-|---|------------|--  1 [S] COG1288 Predicted membrane protein
----------------||------||----|----|||----|||||-||-----|||||||||--  1 [N] COG1291 Flagellar motor component
--|-----|-----------||----|----|-|||||----|||||-||||-|||||-||||---  1 [E] COG1296 Predicted branched-chain amino acid permease (azaleucine resistance)
|||||||||||||||---||-|--||||||-||||||-----|||||-||||-||----|||||||  1 [C] COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
----||-----------|------------||----||----|||||---|--------||||---  1 [G] COG1312 D-mannonate dehydratase
----------------|-|||||||||||||||||||||-|-||||||||||||||||||||||||  1 [U] COG1314 Preprotein translocase subunit SecG
-----------------|----||||----|-----||----||||||||-----||||---|---  1 [NU] COG1317 Flagellar biosynthesis/type III secretory pathway protein
|||||||||||||----|---||||-||||||||||||----|||-|-----|---------|---  1 [K] COG1321 Mn-dependent transcriptional regulator
----------------------||-------|||-----|--|||||-||||||||---|||||||  1 [S] COG1322 Uncharacterized protein conserved in bacteria
|-|-|||||||-|--|||-|-|-|------------------|||||-----|--|--------||  1 [P] COG1324 Uncharacterized protein involved in tolerance to divalent cations
-----------------||-||||--||||||||||||----|||||-||||||||---|||||--  1 [K] COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains
|||---||-|-------|--|---------||||||------|||||-||||---|----------  1 [F] COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase
----------------------||-|-||-------------|||||||||||||-----------  1 [L] COG1330 Exonuclease V gamma subunit
----------------||----||||----|----|||----||||||||-----|||||||||--  1 [NU] COG1338 Flagellar biosynthesis pathway, component FliP
----------------||------||----|----|||----|||||-||-----||||-------  1 [N] COG1345 Flagellar capping protein
--|---||------------||--------||--|-||----|||||-||||-|||-----|----  1 [M] COG1346 Putative effector of murein hydrolase
--||--|||--------|-|----||----|----|||----|||||-||-----|--|||-||--  1 [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins
-----------------|------------|||-|||-----|||-|-||||-||-|||||-|---  1 [M] COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
----------------||----||||----|----|||----||||||||-----|||||||||--  1 [NU] COG1377 Flagellar biosynthesis pathway, component FlhB
--|---||------------||--------||--|-||----|||||-||||-|||-----|----  1 [R] COG1380 Putative effector of murein hydrolase LrgA
------------------|||||||-||||||||||||||--|||||-||||||||---|||||||  1 [L] COG1381 Recombinational DNA repair protein (RecF pathway)
----------------||||||--||||||||||||||||--||||||||||||||||||||||||  1 [S] COG1385 Uncharacterized protein conserved in bacteria
|||-||||||---||-||--||-----||-||--||||----|||||-|-----------|-----  1 [ER] COG1387 Histidinol phosphatase and related hydrolases of the PHP family
----------------|---------||||------------|||||-||||-|||---|||||--  1 [OT] COG1391 Glutamine synthetase adenylyltransferase
-||-----|-------|--|-|--------|--|--------|||-|---------------|---  1 [O] COG1397 ADP-ribosylglycohydrolase
----------------||||-|----||||||||||||----|||||-||||||||----------  1 [R] COG1399 Predicted metal-binding, possibly nucleic acid-binding protein
|-|---|---||----|-|--|-----------|--|-----|--|----------|||-------  1 [V] COG1401 GTPase subunit of restriction endonuclease
---|--------------||-|-----||||||-|||-----|||---|---|--|---|||||--  1 [V] COG1403 Restriction endonuclease
|-|-------|-----|--|-|||--||||||---|||----|------------||||-|-|---  1 [R] COG1408 Predicted phosphohydrolases
|-|---|||||-|||-|-||--||--||||||--|||-----|||||-||||---|---|||||--  1 [R] COG1409 Predicted phosphohydrolases
-----------------|||-|----|||||------|----|||||-|||-|--|---|||||--  1 [E] COG1410 Methionine synthase I, cobalamin-binding domain
|-||---------|||--||--||||--------|-||----||-----|------------|---  1 [C] COG1413 FOG: HEAT repeat
||||||||||------||--||--||----|||||||||-|||||-|---------|||||-----  1 [R] COG1418 Predicted HD superfamily hydrolase
-----------------|-|--||||-----|||||||----|||||-|||||--|--------||  1 [S] COG1426 Uncharacterized protein conserved in bacteria
---||-----|----|-|---|---|----|||||||||||||||||-|-||-------||-|---  1 [F] COG1435 Thymidine kinase
-----------------|---|-|--||||||||||||----|||||-|-||--------------  1 [K] COG1438 Arginine repressor
-------------------------|----||||-|||----|||||-|-----------------  1 [G] COG1440 Phosphotransferase system cellobiose-specific component IIB
------------------------------------------|||||-|-||--------------  1 [H] COG1441 O-succinylbenzoate synthase
---|---------|||----------|||-------------|||-|-------------------  1 [I] COG1443 Isopentenyldiphosphate isomerase
---|--||||||||||--------------------------|||||-|-||--------------  1 [R] COG1444 Predicted P-loop ATPase fused to an acetyltransferase
---|||||--||--|---||----------------------|||-|-|------|---|---|--  1 [E] COG1446 Asparaginase
-------------------------|----||||||||----|||||-|-----------------  1 [G] COG1447 Phosphotransferase system cellobiose-specific component IIA
----------------|---|-||------------------|||||-||--|--|--|---||--  1 [NU] COG1450 Type II secretory pathway, component PulD
||||--|||-------|---||----|---|-------||--|||||-||--||||||||||||-|  1 [R] COG1451 Predicted metal-dependent hydrolase
----------------|-------||----------------|||||-||||||||||||||||||  1 [M] COG1452 Organic solvent tolerance protein OstA
-------------------------|----||||||||----|||||-|-----------------  1 [G] COG1455 Phosphotransferase system cellobiose-specific component IIC
----||||---|-|---------------------|||----|||-|--|-|-||-----------  1 [F] COG1457 Purine-cytosine permease and related proteins
----------------|-||-|--------------------|||||--|---|||-------|--  1 [M] COG1462 Uncharacterized protein involved in formation of curli polymers
----------------|-||-------|||------------|||||-||||||||||||||||||  1 [Q] COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component
----------------||||-|||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG1466 DNA polymerase III, delta subunit
--|-------------||--|||||-----||||-|------|||||-||||||||----||||--  1 [H] COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis
--------|----||--|---|---|||||||||||||-|--|||||-|--|--------------  1 [G] COG1482 Phosphomannose isomerase
-------------||------|-----||-------------|||||-||--||||---|||||||  1 [R] COG1485 Predicted ATPase
--|||||||||||||-||||||--|||||-||||||||||||||||||||-|||||--|||||---  1 [H] COG1488 Nicotinic acid phosphoribosyltransferase
|---||--|-|||---||||----------|------|----|||||-||||-------|||-|--  1 [R] COG1489 DNA-binding protein, stimulates sugar fermentation
-------------||-||--||----|||-||||||||----|||||-||||-|||----------  1 [J] COG1490 D-Tyr-tRNAtyr deacylase
---------------------|||------------||----|||||-||||||||||||||||||  1 [O] COG1495 Disulfide bond formation protein DsbB
----------------|-||||||-||||||---|-||----|||||-||||||||--||||||||  1 [S] COG1496 Uncharacterized conserved protein
----------------|-----||||----|----|||----|||||-||--||||||||||||--  1 [K] COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
-||-------------||--||--|-----------||----|||||-|-|||------||-||--  1 [E] COG1509 Lysine 2,3-aminomutase
-----------------|||----|------|----||----|||----|-|---|-----|||--  1 [R] COG1512 Beta-propeller domains of methanol dehydrogenase type
----------------|-||----------------------|||----|-----|----------  1 [P] COG1513 Cyanate lyase
|||-|||||||||---||-|-|----|---|---|-||----|||||--|-----|---|||||--  1 [J] COG1514 2'-5' RNA ligase
---||||||||||-|-||-|-|--------|-----|-----|||||-----|-------------  1 [L] COG1515 Deoxyinosine 3'endonuclease (endonuclease V)
----------------||------||----|----|||----|||||-||-----||||-------  1 [NUO] COG1516 Flagellin-specific chaperone FliS
|||-|||-|||||---||-||------||---|--|-|----|||||----|--|---|-------  1 [L] COG1518 Uncharacterized protein predicted to be involved in DNA repair
----------------|---|-||------------------|||||-||||||||||||||||||  1 [M] COG1519 3-deoxy-D-manno-octulosonic-acid transferase
||||--|||--------|---|---|-|||------|-----|||||-||--|--|-------|||  1 [S] COG1520 FOG: WD40-like repeat
--|--------|-----||-||||--|||-|-||--||-|--|||||-||||---|---||-|---  1 [G] COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases
|||-||--|-||--------------|||-----||||----|||||-||||---|--||||||--  1 [C] COG1526 Uncharacterized protein required for formate dehydrogenase activity
||||--||||-||-------|---------||||||||----|||||-||||||||----------  1 [J] COG1534 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein
-----------------|------------------|-----|||-|-||-----------|----  1 [Q] COG1535 Isochorismate hydrolase
----------------||----||||----|----|||----||||||||-----|||||||||--  1 [N] COG1536 Flagellar motor switch protein
------||------------||----|--|----|-||----|||||-|||--|||--||------  1 [R] COG1540 Uncharacterized proteins, homologs of lactam utilization protein B
|-|-----|--|-------|||---------------|----|--|--|---|--|----------  1 [H] COG1541 Coenzyme F390 synthetase
-----------------|------||----|-----||----|||||||||||---|||-------  1 [T] COG1551 Carbon storage regulator (could also regulate swarming and quorum sensing)
------|------|-----|-------|||||---||--|--|||--------||-----------  1 [G] COG1554 Trehalose and maltose hydrolases (possible phosphorylases)
--|--------------|||||----|||-||||||||----|||||-||||||||--|-------  1 [L] COG1555 DNA uptake protein and related DNA-binding proteins
---|----|-----------||---------|----||----|||------|-||||||-------  1 [S] COG1556 Uncharacterized conserved protein
----------------||------||----|----|||----||||||||-----|||||||||--  1 [N] COG1558 Flagellar basal body rod protein
----------------|---||--||||||||||-|||----|||||-||||||||||||||||||  1 [R] COG1559 Predicted periplasmic solute-binding protein
----------------||--|----|----|----|||----|||||-||||||||---|||||--  1 [S] COG1561 Uncharacterized stress-induced protein
-----------------|-|||||--||||||||||||----|||||-||||||||||||||||||  1 [L] COG1570 Exonuclease VII, large subunit
---|-------------||||-----||||-|--|||-----|||||-|-||--------------  1 [H] COG1575 1,4-dihydroxy-2-naphthoate octaprenyltransferase
-----------------|--||--------||||||||||--|||||-||||||||||||||||--  1 [S] COG1576 Uncharacterized conserved protein
----------------||------||----|-----||----|||||-||-----||||-------  1 [N] COG1580 Flagellar basal body-associated protein
|-|-||-----|-||---------------------------|||||-|--|--------------  1 [S] COG1584 Predicted membrane protein
||-|--||-||||----|||||----|||||-----------|||||-||-||------|||||--  1 [OU] COG1585 Membrane protein implicated in regulation of membrane protease activity
-|--|||||-|||---||------------|-----||----||||||-|--|--|----------  1 [E] COG1586 S-adenosylmethionine decarboxylase
||||||--||||-||-|-||||||--|||||---||||----|||||-||-||||||||||||---  1 [H] COG1587 Uroporphyrinogen-III synthase
------------------||-|--||||||||||||||----|||||-||||||||---|||||||  1 [M] COG1589 Cell division septal protein
-----------------|--|---|-|----------|----|--||-||||-------||--|--  1 [G] COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
----|--------||--|||-|----|||-||||||||----|||||--|---------||-||--  1 [IR] COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
|-|||---|--------|||-------------|--------||||--------|--|--|-||-|  1 [S] COG1598 Uncharacterized conserved protein
|-|-----|---------||-|--------|-|-||||----|||||-||-----|---|||||--  1 [C] COG1600 Uncharacterized Fe-S protein
---|||----|||--------|||--|-------||||----||||||||||-|||||||||||--  1 [I] COG1607 Acyl-CoA hydrolase
--|-||||||||-|--||-|||||--||||-|--|-||----|||||-||-|||||--||||||--  1 [R] COG1611 Predicted Rossmann fold nucleotide-binding protein
------------------||-------|||-------|----|||||--|--||||---|||||--  1 [P] COG1613 ABC-type sulfate transport system, periplasmic component
----||------------||||--|-----||-|-|||-|--|||-|-||---|||--------||  1 [V] COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF
---|----|-||||--|-||-|----||||----||||----||||||-|--|--|---|||||||  1 [C] COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2
-----------------||-|---|-|---------||----|--||-||||---|---||-||--  1 [G] COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
----------|-----|-||||||-||||--|||--------|||||-||||---|----------  1 [G] COG1640 4-alpha-glucanotransferase
||||||--|||-|||-|---|------||-|---||||----||||||||--|||----|||||--  1 [H] COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)
------------------||-|--------------|-----||||---------|-----|----  1 [S] COG1649 Uncharacterized protein conserved in bacteria
-------------------|-|--||---------||-----|||-|-||-|||||---|||||--  1 [S] COG1652 Uncharacterized protein containing LysM domain
--||---||------------|--------||||||||----|||||-|||||-------------  1 [K] COG1654 Biotin operon repressor
--------------------||----||||||||||||----|||||-||||||||----------  1 [R] COG1660 Predicted P-loop-containing kinase
----------------|---|-||------------------|||||-||||||||||||||||||  1 [M] COG1663 Tetraacyldisaccharide-1-P 4'-kinase
-------------------|-------||-------||----|||||-||||---|--|-------  1 [S] COG1666 Uncharacterized protein conserved in bacteria
------------------------||----|---||||----|||||-||---------|||||--  1 [S] COG1671 Uncharacterized protein conserved in bacteria
-------------------|-||||||||||||||||||---|||||-||||||||||||||||||  1 [D] COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins
----------------||------||----|----|||----||||||||-----|||||||||--  1 [NU] COG1677 Flagellar hook-basal body protein
---------------------|||--||||------------|||||-||||||||---|||||||  1 [K] COG1678 Putative transcriptional regulator
----------------||------||----|----|||----||||||||-----|||||||||--  1 [NU] COG1684 Flagellar biosynthesis pathway, component FliR
--|---|||||||---|||||||||||||-||--||||----|||||-|||||------|||||-|  1 [R] COG1694 Predicted pyrophosphatase
|-|||||||-|||----|-|||----||||||||||||----|||||-|------|------||--  1 [K] COG1695 Predicted transcriptional regulators
---||||||--||--------|----||||-------|----|||----------|-------|--  1 [E] COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family
-----------------|-------------||-|||-----|||||-||-----|-----|----  1 [NU] COG1705 Muramidase (flagellum-specific)
----------------||-------|----------------||||||||-----|||||||||--  1 [N] COG1706 Flagellar basal-body P-ring protein
|-||---------------|-|-----||-------------|---|-------------------  1 [V] COG1715 Restriction endonuclease
||||--|||||||----|------------------------|||||-||||-||-------||--  1 [S] COG1720 Uncharacterized conserved protein
-----------------|-|||----||||||||||||----|||||-||||||||||||||||||  1 [L] COG1722 Exonuclease VII small subunit
----------------|-------------------------|||||-||--||||---|||||||  1 [S] COG1729 Uncharacterized protein conserved in bacteria
---|----|----------|||-----||-|||||||-----|||-|--|-----|||-||||---  1 [M] COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
||||||--|--||-----||||----|||-||--||||----|||||-||-||--|--|||-||--  1 [K] COG1733 Predicted transcriptional regulators
-----------|---------|-----||------|-|-||-|---|------------|--|---  1 [R] COG1735 Predicted metal-dependent hydrolase with the TIM-barrel fold
--||----|-|-|----|--||||-||-------|-|-----|||||-||||-||----||||---  1 [S] COG1738 Uncharacterized conserved protein
--||---------||--|--||---||---||||||||||--|||-|-||||-|||||||||----  1 [S] COG1739 Uncharacterized conserved protein
--|---------------|--------||-----|-||----|||-|--|-----|---||-||--  1 [S] COG1742 Uncharacterized conserved protein
----------------|-------||----|----|------||||||||-----|||||||||--  1 [N] COG1749 Flagellar hook protein FlgE
-------------||||||-|---|--|||-|----||----|||-|-||--||||---|||||||  1 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily
||||||||||||||||||||-|--||||||||||||||----|||||-||||||||||||||||||  1 [K] COG1758 DNA-directed RNA polymerase, subunit K/omega
|||||-|||||||---|-----------------||||----|||||-|-||---|--|||||---  1 [H] COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein
----||---------------|----|----|--|||---|||||-|-||--|--|---|||||--  1 [O] COG1764 Predicted redox protein, regulator of disulfide bond formation
-||-||||-|-||---||---|----|||-|----|-|--|||||||-||---|||---||-||--  1 [O] COG1765 Predicted redox protein, regulator of disulfide bond formation
----------------||------||----|----|||----||||||||-----|||||||||--  1 [NU] COG1766 Flagellar biosynthesis/type III secretory pathway lipoprotein
|||---||||-||-------|-----------|---------|||-|-|||---------------  1 [H] COG1767 Triphosphoribosyl-dephospho-CoA synthetase
-------------------|------||||---|--------|||||-||--|------|||||||  1 [E] COG1770 Protease II
||-----||--------||||---|--||-|-----------|||-|--|--||||-------|--  1 [C] COG1773 Rubredoxin
-|------||----------|---------|-----------|||---------------------  1 [E] COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB
--|-------------|---|---------------------|||||-|||||||||||-------  1 [R] COG1778 Low specificity phosphatase (HAD superfamily)
---------------------|----||||-||||-|--||||||||------------|-|----  1 [F] COG1780 Protein involved in ribonucleotide reduction
|||||||||||||----|------------|-----------|||||||----||-----------  1 [F] COG1781 Aspartate carbamoyltransferase, regulatory subunit
--||---|-----||--|-|-|----|-------|-||----||||---|--|--|-----|----  1 [P] COG1785 Alkaline phosphatase
--------|--|--------||----|||-|-|---||----|------||----|||-|||||-|  1 [I] COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit
----------------|--||-||||----||-|||||----|||||-|||||--||||----|||  1 [M] COG1792 Cell shape-determining protein
------|||----------------------|----|-----|||||----|---|--|||-||--  1 [M] COG1794 Aspartate racemase
--|-|||||-|||---||-|-|------------||||----|||||-||-|---|---||-||--  1 [S] COG1801 Uncharacterized conserved protein
-----------------||------|----|----|||----|||||-|-||---|---|||----  1 [G] COG1803 Methylglyoxal synthase
---------------------|------------||||----|||||-||--||||---|||||||  1 [S] COG1806 Uncharacterized protein conserved in bacteria
------|||-------|-|||---------|-----|-----|||||--|--||||---|||||--  1 [M] COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
--------|--------|--||--------|----|||----|||-|-------------------  1 [R] COG1811 Uncharacterized membrane protein, possible Na+ channel or pump
----------------||------||----|----|||----||||||||-----|||||||||--  1 [N] COG1815 Flagellar basal body protein
-------------||----|----|--|-|||----------|||-|-||-----|---||-||--  1 [F] COG1816 Adenosine deaminase
-------------------------|--------|-|-----|||||-|-||------|-------  1 [R] COG1823 Predicted Na+/dicarboxylate symporter
----------------||||-|||||||||----||||----||||||||||||||||||||||||  1 [J] COG1825 Ribosomal protein L25 (general stress protein Ctc)
---|||||--|||---||---|---------|||-|||----|||||--------|--|||-|---  1 [R] COG1832 Predicted CoA-binding protein
||||||||||||||||||--||--||||||||||||||----||||||||||||||----||||||  1 [J] COG1841 Ribosomal protein L30/L7E
----------------||------||----|----|||----||||||||-----|||||||||--  1 [N] COG1843 Flagellar hook capping protein
---|------||||--|-||-|----||||----||||----||||||-|--|--|---|||||||  1 [C] COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3
---------------------|---|----||||||||----|||||-|-||-||-|||-------  1 [T] COG1854 LuxS protein involved in autoinducer AI2 synthesis
--|-------------|----|--------------------|||||-||-|---|||||--|---  1 [P] COG1858 Cytochrome c peroxidase
--|-|||||||-|||-----||--------------------|||----|---------|------  1 [J] COG1859 RNA:NAD 2'-phosphotransferase
----------------||--|-||-|||||||||||||----||||||||||||||||||||||||  1 [U] COG1862 Preprotein translocase subunit YajC
------------||------||------------|-||----|||||-||||------|||||---  1 [C] COG1866 Phosphoenolpyruvate carboxykinase (ATP)
----------------||------||----|----|||----||||||||-----||||||||---  1 [N] COG1868 Flagellar motor switch protein
-----------------|--------|----|--|-||-|--|||||-|-||--------------  1 [G] COG1869 ABC-type ribose transport system, auxiliary component
|||----|||--|------|--||----|-------------|||||-|--|-------|--||||  1 [S] COG1872 Uncharacterized conserved protein
|---||----|--|||----------||||------------|||-|--------|------|---  1 [G] COG1877 Trehalose-6-phosphatase
---||||||--||--------|----||||-------|----|||----------|---|||||--  1 [I] COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit
----------------||----||||----|----|||----||||||||-----|||||||||--  1 [NU] COG1886 Flagellar motor switch/type III secretory pathway protein
---|--|||-|-|||-|--|------|||-|||-||||----|||||-||-----|------||--  1 [H] COG1893 Ketopantoate reductase
|-------------|-||||-|-----||-------------||||||-|--||||---|||||||  1 [C] COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit
-----------------|------------||-|--||----|||||-|---------||||----  1 [E] COG1897 Homoserine trans-succinylase
|-|--||||--||-----||||----|||||||||-||----|---|--|-|||||--||||||--  1 [M] COG1898 dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes
-----------------|--------|---||----||----|||||-------------||||--  1 [G] COG1904 Glucuronate isomerase
|-------------|-||||-|-----||-------------||||||-|--||||---|||||||  1 [C] COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit
----||-----|-||----|||----||||||-|||||----|||||--|||||||---||||---  1 [P] COG1914 Mn2+ and Fe2+ transporters of the NRAMP family
|||----|||-------||--|--------||--||------|||||-||--|--|-||----|--  1 [P] COG1918 Fe2+ transport system protein A
||--|----|------|-------------------------|||||--|||----|||||-|---  1 [E] COG1921 Selenocysteine synthase [seryl-tRNASer selenium transferase]
-----------------|||-|--|-----|---|||-----|||||-|---|------|-|||--  1 [M] COG1922 Teichoic acid biosynthesis proteins
-|--------------||------------|---||||----|||||-||||||||----||||--  1 [R] COG1923 Uncharacterized host factor I protein
|||-----||------||--|---------||---|------|||---------------------  1 [I] COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain)
--|----------||----|------||||-|---|||----||||||||||||||--||||||--  1 [HE] COG1932 Phosphoserine aminotransferase
----------------|-||----------------------|||||-||||||||||||||||--  1 [S] COG1934 Uncharacterized protein conserved in bacteria
|-------|----------|------|----|||||||----||||------|||||||||-||--  1 [R] COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog
--||||-----|-----|-|||------|-|--|---|----|||||-|||--|||||----||--  1 [L] COG1943 Transposase and inactivated derivatives
||||-----|-----------------||-------------|||||--|||-------||-|---  1 [S] COG1944 Uncharacterized conserved protein
-------------|-|----------||||------------|||||-|||||------|||||--  1 [I] COG1946 Acyl-CoA thioesterase
----------------|||||||-|-|||||---|||||---||||||||||||||||||||||--  1 [I] COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase
-------------||-----------||||------------||||||||||||||----------  1 [A] COG1949 Oligoribonuclease (3'->5' exoribonuclease)
-|----------------------------------------||||||||||||||---|||||||  1 [U] COG1952 Preprotein translocase subunit SecB
-----------||||---------------------|-----|||||--|-----|----||||--  1 [FH] COG1953 Cytosine/uracil/thiamine/allantoin permeases
-----------------|--|---------|---||||----|||---------------------  1 [K] COG1954 Glycerol-3-phosphate responsive antiterminator (mRNA-binding)
---|||-------|---|------------||||||||----|||||-||-||||-------||--  1 [T] COG1956 GAF domain-containing protein
-------------|||--------------------------||||||||||-|||--------||  1 [P] COG1965 Protein implicated in iron transport, frataxin homolog
|--------|||----||||||---||||||||||-||----||||||||--||||--||||||--  1 [V] COG1968 Uncharacterized bacitracin resistance protein
----------------|-------------------------|||-|---------|||-------  1 [C] COG1969 Ni,Fe-hydrogenase I cytochrome b subunit
--|---------------|-||----||||-||||||-----|||||-|||||--|---|||||--  1 [M] COG1970 Large-conductance mechanosensitive channel
|-|-----------------|-----|---|-----||----|||||--|--|||---|-------  1 [S] COG1971 Predicted membrane protein
--||||-||-||----|-||-|-----||-----||||----|||||-||||---|||||||||--  1 [H] COG1977 Molybdopterin converting factor, small subunit
-----------------|-||---------|----|||----|||||-|--|--------------  1 [C] COG1979 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family
--|---||---------|--------|---||||-|||----|||||-|-----------------  1 [KT] COG1983 Putative stress-responsive transcriptional regulator
------||-----|------||----||||----|-||----|||||-|||--|||--||---|--  1 [E] COG1984 Allophanate hydrolase subunit 2
||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG1985 Pyrimidine reductase, riboflavin biosynthesis
||--||--|||||------------------------|----|||||-|-----------------  1 [S] COG1986 Uncharacterized conserved protein
----------------||------||----|----|||----||||||||-----|||||||||--  1 [NU] COG1987 Flagellar biosynthesis pathway, component FliQ
----------------|-|||----------------|----|||||-||-|||||||||||||--  1 [H] COG1995 Pyridoxal phosphate biosynthesis protein
---------------------|--|-|||||---|||||||||||||--|||||||----|--|||  1 [S] COG2001 Uncharacterized protein conserved in bacteria
---|--|||-|||-----||-------||-|----|||----|||--------------||-|---  1 [K] COG2002 Regulators of stationary/sporulation gene expression
|-|-----||||------------------------------|||||--|||---|--|||-||--  1 [R] COG2005 N-terminal domain of molybdenum-binding protein
---|---------||--|-|||--------|---||-|----|||||-||-----|---|||||--  1 [E] COG2008 Threonine aldolase
---|||--|-|-|||------|||---|||----|-||----|||||-||--||||||||||||||  1 [C] COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit
--------------------||-||-|---||||||||----|||||-||||||||||||||||--  1 [P] COG2011 ABC-type metal ion transport system, permease component
-------------|-------------||-------------|||---||-------------|--  1 [Q] COG2015 Alkyl sulfatase and related hydrolases
----------------|-||||----|||||-----||----|||||-||--||||--||||||--  1 [H] COG2022 Uncharacterized enzyme of thiazole biosynthesis
-||---|-|---|-----|||------||----|--------|--||-|------|---||-----  1 [JD] COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system
--|---------------||-|----||||------|-----|||||-||||||||----------  1 [M] COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)
---|----|--|-||-----||----||||----|-|-----|--||-||-----|---|||||--  1 [I] COG2030 Acyl dehydratase
--------|---|-------|-----|-----|----|----|------||-----||--------  1 [I] COG2031 Short chain fatty acids transporter
--|----------||-|----|-----||||-----|-----|||||-|--|-|||----||-|--  1 [P] COG2032 Cu/Zn superoxide dismutase
|||||||||||||-----||||----|||||------|----|||-|-||-----|---|||||--  1 [H] COG2038 NaMN:DMB phosphoribosyltransferase
-------------||---|--------||||-----|-----|----------------|--|---  1 [E] COG2040 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)
--||||--|-|||---|--|-|----|||-------|-----|||||--|-|---|--||||||--  1 [R] COG2041 Sulfite oxidase and related enzymes
------||-----|------||----||||----|-||----|||-|-|||--|||--||---|--  1 [E] COG2049 Allophanate hydrolase subunit 1
-----------|--------||----|||-|-|---||----|------||----|||-|||||-|  1 [I] COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit
---|||------------||-|-----||-|---||------|||||--|-----|---||-||--  1 [P] COG2060 K+-transporting ATPase, A chain
--------|-|||---|-||------||||------------|||||-|||||--|--||||||--  1 [T] COG2062 Phosphohistidine phosphatase SixA
----------------||------------------------||||||||-----|||||||||--  1 [N] COG2063 Flagellar basal body L-ring protein
----------------|---|---------------------|||||-|||||||-||-|||||--  1 [I] COG2067 Long-chain fatty acid transport protein
|--------||||--------|-----||-------||----|||----------|---||-||--  1 [R] COG2068 Uncharacterized MobA-related protein
--------------|-----|------|||||||-|------|||----|--------||||||||  1 [R] COG2071 Predicted glutamine amidotransferases
----------------|---------|||-||-|||||-|--|||||-||||---||||-------  1 [O] COG2077 Peroxiredoxin
|---||----||||------------|||-------||----|||-|--|-----|---||-|---  1 [R] COG2079 Uncharacterized protein involved in propionate catabolism
------------------||----------||||||||----|||||-||||---|---|||-|--  1 [R] COG2081 Predicted flavoproteins
------------------||||----|||-|----|-|----|||-|-||-----|---||||---  1 [H] COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase
------------------||-|--------||--|-||----|||||-|-||--------|-|---  1 [R] COG2103 Predicted sugar phosphate isomerase
|-|||||||-------|-||||----|||||-----||----||--|-||--||||--||-|||--  1 [H] COG2104 Sulfur transfer protein involved in thiamine biosynthesis
-||---|---||------||-|--------------||----|||||-||-----|----------  1 [S] COG2105 Uncharacterized conserved protein
--||||||--|------|||||-----||-------------|||||-||-----|---||||---  1 [H] COG2109 ATP:corrinoid adenosyltransferase
--|-||||||||||--||--||-----||---|-||------|||-|--|-----|------|---  1 [R] COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1
--|----------------------|-----||--||-----|||||--|-----|---||||---  1 [E] COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components
-----------------|-------------|----||----|||||---|--------||||---  1 [G] COG2115 Xylose isomerase
--|---||-|-|-|||-----|----||||----|-||----|--|-------------||||---  1 [S] COG2120 Uncharacterized proteins, LmbE homologs
------------------||-|----|||||-----------|||||-||--||||||||||||--  1 [S] COG2127 Uncharacterized conserved protein
---|---------||----|--------------|-|-----|||-|--|-----|------||--  1 [R] COG2130 Putative NADP-dependent oxidoreductases
----------|-------||-|---|-|||-------|----|||-|--|--|--|---||-||--  1 [G] COG2133 Glucose/sorbosone dehydrogenases
---------------------------|||------------|||||---------||--------  1 [I] COG2134 CDP-diacylglycerol pyrophosphatase
---|---------|-----|------||||------|-----|||-|--|---------||||---  1 [S] COG2135 Uncharacterized conserved protein
-----------------|--||--|-||||||||||||----|||||-||||-|||---|------  1 [R] COG2137 Uncharacterized protein conserved in bacteria
----||--|---|--------|-----|||------------|||||-||--||||---|||||||  1 [C] COG2142 Succinate dehydrogenase, hydrophobic anchor subunit
--|---|||----||-----------|---||-|||||----|||-|---||----||-|------  1 [H] COG2145 Hydroxyethylthiazole kinase, sugar kinase family
---|-------------|||||----|---|--||-||----|||-|-||||||||--||||||--  1 [M] COG2148 Sugar transferases involved in lipopolysaccharide synthesis
----------------|-||------|||-------------|||-|-------------------  1 [S] COG2149 Predicted membrane protein
|||-||||-||||----|---|----||||-|||||||----|---------|--|---|||||--  1 [R] COG2151 Predicted metal-sulfur cluster biosynthetic enzyme
--------------|---|-------|||--|-----|----|||-|-||-----------|----  1 [R] COG2153 Predicted acyltransferase
---|||------------||-|-----||-|---||------|||||--|-----|---||-||--  1 [P] COG2156 K+-transporting ATPase, c chain
-----------------|------------|-----||----|||||-------------|-----  1 [G] COG2160 L-arabinose isomerase
---------------------------||-----|-||----|||-|--|------------||--  1 [Q] COG2162 Arylamine N-acetyltransferase
|----------------|------------------------||||||||||--------------  1 [P] COG2168 Uncharacterized conserved protein involved in oxidation of intracellular sulfur
---------------------------||--|---|||----|||||-||-----|---|||||-|  1 [F] COG2169 Adenosine deaminase
---|--------------||------|||-------------|||-|--|-----|----------  1 [S] COG2170 Uncharacterized conserved protein
---------|-------|--------||||||-|||||----||||||||||||||||||||||||  1 [E] COG2171 Tetrahydrodipicolinate N-succinyltransferase
------------------||-------||-------------|||-|---------------||--  1 [M] COG2173 D-alanyl-D-alanine dipeptidase
-------------||------------|||------------||||--||-----|------|---  1 [Q] COG2175 Probable taurine catabolism dioxygenase
-------------------|||----||||||||-|||----|||||-|||||||----|||||--  1 [D] COG2177 Cell division protein
----|-||--|||----|---|---------|||||||----|||||-|----------|------  1 [G] COG2182 Maltose-binding periplasmic proteins/domains
-------------|||---||---|-|---|||||||||---|||||-||||||||---||||---  1 [K] COG2183 Transcriptional accessory protein
---------------------------||----|--------|||-|--||-|||-||-||-|---  1 [D] COG2184 Protein involved in cell division
---||||||--||-------||----||||-------|----|||----------|---|||||--  1 [I] COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)
------------------||-------|||------------|||||-||--||||---|||||--  1 [P] COG2193 Bacterioferritin (cytochrome b1)
--||--|||--------|-|----||----|-----||----|||||-||--|--|--|||-||--  1 [NT] COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain
|-||----|-----|-||||-|-----||||---|-||----|||---||-----|---|||||--  1 [T] COG2203 FOG: GAF domain
------------------||-|-----||-|---||------|||||-||-----|--|||-||--  1 [T] COG2205 Osmosensitive K+ channel histidine kinase
---|---------|||-|||-|--||----|---------|||||-|-||--|||-||||||||--  1 [O] COG2214 DnaJ-class molecular chaperone
-|------------------|---|-----------------|||||---||---|---||||---  1 [R] COG2215 ABC-type uncharacterized transport system, permease component
---|||------------||-|-----||-|---||------|||||--|-----|--|||-||--  1 [P] COG2216 High-affinity K+ transport system, ATPase chain B
||||||||||||||---|||||----|||-|-||||||----|||||-||-||--|--|||||--|  1 [R] COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold
-----------|-||------|----||||-------|----|||||-||-----|---|||||--  1 [C] COG2224 Isocitrate lyase
--|-||----||-||-||||||||--||||----||||----|||||-||-|||||||||||||||  1 [H] COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis
-------------||---||-|--------------------|||||-||-|||||---|||||||  1 [H] COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase
--|-------------|----|----|||||-----------|||||-||-----|||||||||--  1 [M] COG2230 Cyclopropane fatty acid synthase and related methyltransferases
---||||||||||-----||------||||||-||||-----|---|--|-----|------||--  1 [S] COG2246 Predicted membrane protein
-----------------||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG2255 Holliday junction resolvasome, helicase subunit
-------------||--|--||----|||||||||||||---|||||-||||||||||||||||--  1 [L] COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
---------------------|----|||-|---||||----|||-|--||----|--||-|----  1 [S] COG2258 Uncharacterized protein conserved in bacteria
-|||--||-||||---||||||||--||||||||||||----|||||-||-|||||---|||||--  1 [R] COG2262 GTPases
----------------||||||--------||||||||----|||||-||||||||||||||||--  1 [J] COG2264 Ribosomal protein L11 methylase
------------------||------|----|----||----|||-|--|------------|---  1 [S] COG2268 Uncharacterized protein conserved in bacteria
----------------|-------|-----------------|||||||-|||------||-||--  1 [J] COG2269 Truncated, possibly inactive, lysyl-tRNA synthetase (class II)
---|-------||-------||----|||--||---------|||||-|||----|---|||||--  1 [G] COG2301 Citrate lyase beta subunit
||-|-----|---------|-|-----|||----|-------||||---|-----|--||||||--  1 [E] COG2303 Choline dehydrogenase and related flavoproteins
--|-----|--||-----||||---|||||------||----|--||-||------------|---  1 [R] COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain
---|-----------------|----|---------||----|||||-----|----------|--  1 [S] COG2311 Predicted membrane protein
--------------|--|---|------------||------|||--------------||-|---  1 [Q] COG2313 Uncharacterized enzyme involved in pigment biosynthesis
---------------------|----|||---|---------|||||--|-|---|---||||---  1 [R] COG2321 Predicted metalloprotease
-------------------|||--------||-|--||----|||-|-------------|-----  1 [S] COG2323 Predicted membrane protein
|----------------|||-|--------|-----------|||-|------------|-|----  1 [S] COG2327 Uncharacterized conserved protein
--|------------------|--------------------|||||-|||||------|||||||  1 [O] COG2332 Cytochrome c-type biogenesis protein CcmE
---|---------------|-|--------||||||||----|||||-||||||||----------  1 [R] COG2333 Predicted hydrolase (metallo-beta-lactamase superfamily)
--|---------------|-||--------------||----|||||-||---|||---|||||--  1 [R] COG2334 Putative homoserine kinase type II (protein kinase fold)
------------------||||----|---|-----|-----|||||-||||-|||---|||||--  1 [S] COG2350 Uncharacterized protein conserved in bacteria
--------------|------|--------------||----|||-|--|-----|--||||||--  1 [R] COG2351 Transthyretin-like protein
------------------||-|----|--|--||--------|||||-||||-|||-------|--  1 [C] COG2352 Phosphoenolpyruvate carboxylase
----||---------------|----|||-----||------|||||-||--|||||||||-||--  1 [S] COG2353 Uncharacterized conserved protein
---------------------|----|||-------------|||-|-||---|-------|-|--  1 [S] COG2354 Uncharacterized protein conserved in bacteria
---------------------|--------------|-----||||||||----------------  1 [L] COG2356 Endonuclease I
------------------||-|--------------------|||||-||--||||--||||||--  1 [O] COG2360 Leu/Phe-tRNA-protein transferase
--------------|----|-|------------||||----|||||-||||-------|||||--  1 [S] COG2363 Uncharacterized small membrane protein
---------------------|----|--------|||----|||||--------|----|-|---  1 [R] COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC
---------------------|----|||-------------|||-|-||-----|---||-----  1 [P] COG2375 Siderophore-interacting protein
---------|--------||-|--------------------|||||-||||||||---|||||--  1 [O] COG2377 Predicted molecular chaperone distantly related to HSP70-fold metalloproteases
--|-----|------------|--------------------|||||-|||||------|||||--  1 [O] COG2386 ABC-type transport system involved in cytochrome c biogenesis, permease component
--------|---|-------||----|----|--||------|||---||-|-------|||||--  1 [R] COG2388 Predicted acetyltransferase
------||--|-|----|------------|--|--------|||||---|---------------  1 [G] COG2407 L-fucose isomerase and related proteins
-||-|||||-|-|-----------------|-----------|||---------------------  1 [C] COG2414 Aldehyde:ferredoxin oxidoreductase
-||------||||-----------------------------|||||-|-----------------  1 [R] COG2425 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain
------||--|||-------|---------------------|||||-|-||-||-----------  1 [S] COG2431 Predicted membrane protein
-||---||--||-||----|-|----|---------------||||--||----------------  1 [T] COG2453 Predicted protein-tyrosine phosphatase
-------------------|||----|---||||||||||--|||||-|----|||----------  1 [S] COG2501 Uncharacterized conserved protein
--------------------|---|-------||----|---|||||---||--------------  1 [E] COG2502 Asparagine synthetase A
----||----|||------|------|||------|||----|||-|-||--||||----|-||--  1 [G] COG2513 PEP phosphonomutase and related enzymes
------||------|--|-|----------------------|||||-|------|--|---||--  1 [E] COG2515 1-aminocyclopropane-1-carboxylate deaminase
||||--|||||||-|--|------------------------|||||-||--||||||||||||--  1 [O] COG2518 Protein-L-isoaspartate carboxylmethyltransferase
-|----------------------------------------|||-|--|--------|-------  1 [R] COG2603 Predicted ATPase
---------------------|----||||------------||||||||||||||------||--  1 [C] COG2609 Pyruvate dehydrogenase complex, dehydrogenase (E1) component
--------------|---------------||-||||-----||||||-|-----|----------  1 [G] COG2706 3-carboxymuconate cyclase
------------------------------|----|||----|||||---||-||-----------  1 [S] COG2707 Predicted membrane protein
------------------------------------------|||||-||--|----------|--  1 [E] COG2716 Glycine cleavage system regulatory protein
-------------------|-|--|-----|-----------|||||--|-|---|--||||-|--  1 [S] COG2717 Predicted membrane protein
---|--------------------------|-----||----|||||-||----------|-|---  1 [S] COG2718 Uncharacterized conserved protein
---|--------------------------|-----||----|||||-||----------|-|---  1 [S] COG2719 Uncharacterized conserved protein
------------------------------|-----|-----|||||------|------------  1 [K] COG2732 Barstar, RNAse (barnase) inhibitor
--------------------------|||-|-----------|||-|-----|---------|---  1 [S] COG2733 Predicted membrane protein
----------------||------------|-----||----|||||-||-----|----------  1 [KNU] COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor)
-----------|-||---||-------|||||||-|||----|||||-||-|-|||--||||||--  1 [E] COG2755 Lysophospholipase L1 and related esterases
-------------------|------|||-||--||-|----|||-|--|-----|----|-||--  1 [S] COG2764 Uncharacterized protein conserved in bacteria
---|--------------------------|-----||----|||||-||----------|-|---  1 [T] COG2766 Putative Ser protein kinase
----------------||||||--------|-----------|||||-||--||||----------  1 [NU] COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG2812 DNA polymerase III, gamma/tau subunits
--|----------||------|----|||-|-----------|||||-||||-------|||||--  1 [L] COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding
--------------------------||||-|||||-|----|||||-||||-|||---|||||--  1 [L] COG2818 3-methyladenine DNA glycosylase
---|------|||-----------|----|-||---------|||||-|-||--------------  1 [F] COG2820 Uridine phosphorylase
------------------||----------------------||||||||||-|||---|||||--  1 [M] COG2821 Membrane-bound lytic murein transglycosylase
----------------------------------|||-----||||-------||-----------  1 [P] COG2822 Predicted periplasmic lipoprotein involved in iron transport
--------------------------|----|||-|------|||||-||||-|||||||||||--  1 [P] COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism
----------------||---|||||----------------|||||-||||-|||-------|||  1 [M] COG2825 Outer membrane protein
---|----------------|----------|||||||----|||||-||---||-----||||--  1 [L] COG2827 Predicted endonuclease containing a URI domain
------------------------------------|-----|||---||--||||---||-|---  1 [S] COG2828 Uncharacterized protein conserved in bacteria
------------------------------------------|||||----|-||-|||-------  1 [M] COG2829 Outer membrane phospholipase A
--------------------||-----------||-------|||-|-||||-||----|||----  1 [S] COG2832 Uncharacterized protein conserved in bacteria
-|||----|-------|----|--||----|-----||----|||||-||||||||||||||||||  1 [M] COG2834 Outer membrane lipoprotein-sorting protein
--||------|||-------------||||------------|||||-||-|||||----||||--  1 [S] COG2835 Uncharacterized conserved protein
------------------------------------------|||----|-|-||-|||--|----  1 [S] COG2841 Uncharacterized protein conserved in bacteria
--------------------------|||-------------|||||-||||-|||---|||||--  1 [O] COG2844 UTP:GlnB (protein PII) uridylyltransferase
------------------------------|---|-------|||||---|--|||----|-----  1 [D] COG2846 Regulator of cell morphogenesis and NO signaling
------------------------------------|-----|||||--|||||||----------  1 [S] COG2850 Uncharacterized conserved protein
-------------------|-|-------------|------|-------|--||-----|--|--  1 [S] COG2852 Uncharacterized protein conserved in bacteria
--------------------|---------------------|||||-||||||||--|----|||  1 [M] COG2853 Surface lipoprotein
------------------------------------------|||||-||||||||--|----|||  1 [Q] COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component
--------|-----------|-----|----|||||------|||||--|||-|||--||||||--  1 [S] COG2855 Predicted membrane protein
-------------------------|-----------|----|||-|--|||------|||-||--  1 [S] COG2861 Uncharacterized protein conserved in bacteria
--|-------------|----|--------------------|||-||||||---|||||---|--  1 [S] COG2862 Predicted membrane protein
--|----------||---|-----------------||----|||||--|---|||-------|--  1 [E] COG2866 Predicted carboxypeptidase
-------------||---------------------------|||||-||-|||||---|||||||  1 [I] COG2867 Oligoketide cyclase/lipid transport protein
-|--------------|---|---------------------||||||-|||-||||||---||--  1 [M] COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase
----------------|---|-||------------------|||||-||||||||||||||||||  1 [M] COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase
--|--------------|--|---------------------||||||||||||||----------  1 [C] COG2878 Predicted NADH:ubiquinone oxidoreductase, subunit RnfB
-----------------|------|-----|-----||----||||||||-----|----------  1 [NUO] COG2882 Flagellar biosynthesis chaperone
-------------------|-|----||||||||-|||----|||||-|||||||----|||||--  1 [D] COG2884 Predicted ATPase involved in cell division
-------------------|----|------|-|||||----|||||-|||||--|----------  1 [M] COG2891 Cell shape-determining protein
----------------||||||--------|----|||----||||||||--||||||-||||---  1 [D] COG2894 Septum formation inhibitor-activating ATPase
--------------------------|||-|-----------||||||||--||||---|||||--  1 [P] COG2895 GTPases - Sulfate adenylate transferase subunit 1
|||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||--  1 [H] COG2896 Molybdenum cofactor biosynthesis enzyme
------------------------------------------|||||-|||||||----||||---  1 [S] COG2900 Uncharacterized protein conserved in bacteria
------------------------------------------||||||||||||||----------  1 [KL] COG2901 Factor for inversion stimulation Fis, transcriptional activator
------------------------------------------|||||-|||||--|--------||  1 [S] COG2904 Uncharacterized protein conserved in bacteria
------------------|---------|-------------||-||-||--||||-------|--  1 [P] COG2906 Bacterioferritin-associated ferredoxin
-----------------|------------------------|||||-|||||||||||||-||--  1 [S] COG2908 Uncharacterized protein conserved in bacteria
---------------------------||-|-----------|||||-||----------------  1 [K] COG2909 ATP-dependent transcriptional regulator
------------------------------------------||||||||||||||---|||||--  1 [S] COG2911 Uncharacterized protein conserved in bacteria
-------------------|--||------------------|||||||||||--|-------|--  1 [S] COG2912 Uncharacterized conserved protein
------------------------------------------||||||||||||||---|||||||  1 [J] COG2913 Small protein A (tmRNA-binding)
------------------------------------------||||||||||||||----------  1 [S] COG2914 Uncharacterized protein conserved in bacteria
------------------------------------------|||||||||||-------------  1 [R] COG2915 Uncharacterized protein involved in purine metabolism
------------------------------------------||||||||||-|||----||||||  1 [D] COG2917 Intracellular septation protein A
------------------------------|----|------||||||||-|--------------  1 [H] COG2918 Gamma-glutamylcysteine synthetase
------------------------||||||-|||||||----||||||||||||||---|||||||  1 [D] COG2919 Septum formation initiator
--------|-|-------------------------------||||||||||--------------  1 [P] COG2920 Dissimilatory sulfite reductase (desulfoviridin), gamma subunit
------------------------------------------||||||||||||||----------  1 [S] COG2921 Uncharacterized conserved protein
------------------------------------------|||||||---|||-----------  1 [S] COG2922 Uncharacterized protein conserved in bacteria
|-|--------------|------------------------||||||||||--------------  1 [P] COG2923 Uncharacterized protein involved in the oxidation of intracellular sulfur
------------------------------------------||||||||||||||----------  1 [CO] COG2924 Fe-S cluster protector protein
------------------------------------------|||||||||||--|----------  1 [L] COG2925 Exonuclease I
--------------------|---------------------|||||||-||--------------  1 [S] COG2926 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||||||---|||||||  1 [L] COG2927 DNA polymerase III, chi subunit
------------------------------------------|||||--||||-------------  1 [R] COG2933 Predicted SAM-dependent methyltransferase
---------------------------|||------------|||||-|||||-------------  1 [I] COG2937 Glycerol-3-phosphate O-acyltransferase
-------------||---------------------------|||||-||||||||---|||||||  1 [S] COG2938 Uncharacterized conserved protein
------------------||----------------------|||-|-----|--|---|||||--  1 [G] COG2942 N-acyl-D-glucosamine 2-epimerase
------------------------------------------|||-|-||--|--|-------|--  1 [M] COG2943 Membrane glycosyltransferase
-------------------|----------------------|||-|-|---||||---||----|  1 [K] COG2944 Predicted transcriptional regulator
--------------------------|||-------------|||||-||-|||||---|||||--  1 [M] COG2951 Membrane-bound lytic murein transglycosylase B
------------------------------------------|||||-|-||||||----------  1 [G] COG2956 Predicted N-acetylglucosaminyl transferase
------------------------------------------|||||-||||-|||----------  1 [H] COG2959 Uncharacterized enzyme of heme biosynthesis
------------------------------------------|||||-||--||||---||||---  1 [S] COG2960 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||||||---|||||-|  1 [R] COG2961 Protein involved in catabolism of external DNA
--------------------------|-------||||----|||||-||||---|---|||||--  1 [R] COG2962 Predicted permeases
--------------------|-----------|---------|||||-||||---|--|-|-----  1 [S] COG2964 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||-|||----------  1 [L] COG2965 Primosomal replication protein N
|------------||-----|-----|||-|--|||-|----|||||-|-|||-----|-------  1 [S] COG2966 Uncharacterized conserved protein
---------------------|--------------------|||||-||--|--|---|||||--  1 [P] COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport
--||--------------||-------||--------|----|||||-|---|------|||||--  1 [S] COG2968 Uncharacterized conserved protein
------------------------------------------|||||-||||||||----------  1 [R] COG2969 Stringent starvation protein B
----------------------|-------------------|||||-|-|||-------------  1 [K] COG2973 Trp operon repressor
------------------------------------------|||||-||||||||----------  1 [L] COG2974 DNA recombination-dependent growth factor C
------------------------------------------|||||-|||--|||----------  1 [S] COG2975 Uncharacterized protein conserved in bacteria
------------------------------------------||||||||||||||----------  1 [S] COG2976 Uncharacterized protein conserved in bacteria
--------------------------||||------------|||||-||---------|-||---  1 [Q] COG2977 Phosphopantetheinyl transferase component of siderophore synthetase
--------------------|-----|-------|--|----||||--|--|-||--------|--  1 [H] COG2978 Putative p-aminobenzoyl-glutamate transporter
------------------------------------------|||-|-||-|-||----||||---  1 [S] COG2979 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||||||----------  1 [M] COG2980 Rare lipoprotein B
------------------|-----------------------|||||-||||-------||||---  1 [E] COG2981 Uncharacterized protein involved in cysteine biosynthesis
-|----------------------------------------|||||-||||-------|||||--  1 [S] COG2983 Uncharacterized conserved protein
------------------||----------------------|||||-||----------------  1 [E] COG2988 Succinylglutamate desuccinylase
------------------------------------------|||||-|-||-------|||||--  1 [S] COG2989 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||-||---|---|---  1 [S] COG2990 Uncharacterized protein conserved in bacteria
--------------------|---------------------|||-|-|---------|-------  1 [R] COG2992 Uncharacterized FlgJ-related protein
------------------------------------------|||-|-|--|-||-----------  1 [O] COG2999 Glutaredoxin 2
------------------||------|-------|-------|||||-|--|--------------  1 [G] COG3001 Fructosamine-3-kinase
------------------------------------------|||||-|-||----|||-||||-|  1 [P] COG3004 Na+/H+ antiporter
------------------------------------------|||||-|-||--------------  1 [D] COG3006 Uncharacterized protein involved in chromosome partitioning
------------------------------------------|||||-||---|||----------  1 [S] COG3009 Uncharacterized protein conserved in bacteria
--------------------|----||----|||||---|--|||||-|-||---------|----  1 [G] COG3010 Putative N-acetylmannosamine-6-phosphate epimerase
---------------------|----|---------------|||||-||||-|-|----------  1 [S] COG3012 Uncharacterized protein conserved in bacteria
-|----------------------------------------|||||-|--|--------------  1 [S] COG3013 Uncharacterized conserved protein
------------------------|-----------------||||--|-----------------  1 [MP] COG3015 Uncharacterized lipoprotein NlpE involved in copper resistance
------------------------------------------|||||-||||||||----------  1 [M] COG3017 Outer membrane lipoprotein involved in outer membrane biogenesis
-------------------|-|--------------------|||||-|--|-------|-|||--  1 [S] COG3021 Uncharacterized protein conserved in bacteria
----------------|---|-----|-----||--------|||||-||||-|||--|----|-|  1 [S] COG3022 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||-|||----||||--  1 [S] COG3024 Uncharacterized protein conserved in bacteria
--|---------------------------------------|||||-||||---|------||--  1 [S] COG3025 Uncharacterized conserved protein
------------------------------------------|||||-||||---|----------  1 [T] COG3026 Negative regulator of sigma E activity
-----------------------|------|---||||----|||||-|||||||----|||||||  1 [S] COG3027 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||||||----------  1 [S] COG3028 Uncharacterized protein conserved in bacteria
---------------------------||-------------|||||-|-||--------------  1 [C] COG3029 Fumarate reductase subunit C
---|--------|-------|---------------------|||---|--|--------------  1 [E] COG3033 Tryptophanase
----------------|-------------------------|||||-||------|||||||---  1 [S] COG3034 Uncharacterized protein conserved in bacteria
------------------------------------------|--||-||||-|------------  1 [S] COG3036 Uncharacterized protein conserved in bacteria
--------------------------|-----||||-|-||-|||||-|--|--------------  1 [S] COG3037 Uncharacterized protein conserved in bacteria
--------------------------|---------------|||-|-||--------||--||--  1 [M] COG3040 Bacterial lipocalin
-------------------|-------------|--------|||-|-|-|-|---||-|------  1 [S] COG3041 Uncharacterized protein conserved in bacteria
--------|---------------------------------|||||-|----|||------|---  1 [R] COG3042 Putative hemolysin
------------------------------------------|||||-||||------|||-----  1 [C] COG3043 Nitrate reductase cytochrome c-type subunit
------------------------------------------|||||-||---|||---||||---  1 [S] COG3045 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||-||--|---|-|||||  1 [M] COG3047 Outer membrane protein W
--------------------|---------------||----|||-|-||----------------  1 [E] COG3048 D-serine dehydratase
------------------------------------------|||||-|-||--------------  1 [L] COG3050 DNA polymerase III, psi subunit
--------------------|----------||---------|||-|-|-|---------------  1 [C] COG3051 Citrate lyase, alpha subunit
--------------------|----------||---------|||-|-|-|---------------  1 [C] COG3052 Citrate lyase, gamma subunit
--------------------|----------||---------|||-|-|-|---------------  1 [C] COG3053 Citrate lyase synthetase
------------------------------------------|||||-|-||--------------  1 [R] COG3054 Predicted transcriptional regulator
--------------------|---------------------|||||-|-||---------|----  1 [S] COG3055 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  1 [M] COG3056 Uncharacterized lipoprotein
------------------------------------------|||||-|-||--------------  1 [L] COG3057 Negative regulator of replication initiationR
----------------|-------------------------|||||--|||--------|-----  1 [O] COG3058 Uncharacterized protein involved in formate dehydrogenase formation
------------------------------------------|||-|-|-||----||--------  1 [S] COG3059 Predicted membrane protein
------------------------------------------|||||-|-||--------------  1 [KE] COG3060 Transcriptional regulator of met regulon
------------------------------------------|||||-|-||--------------  1 [M] COG3061 Cell envelope opacity-associated protein A
------------------------------------------|||||-||||------|||-----  1 [P] COG3062 Uncharacterized protein involved in formation of periplasmic nitrate reductase
------------------------------------------|||||-|-||--------------  1 [M] COG3064 Membrane protein involved in colicin uptake
------------------------------------------|||||-|-||--------------  1 [L] COG3066 DNA mismatch repair protein
------------------------------------------|||||-||||--------------  1 [P] COG3067 Na+/H+ antiporter
------------------------------------------|||||-|-||--------------  1 [S] COG3068 Uncharacterized protein conserved in bacteria
------------------------------|--|||------|||||-||||-|-|----|-||-|  1 [K] COG3070 Regulator of competence-specific genes
------------------------------------------|||||-||||||||----------  1 [H] COG3071 Uncharacterized enzyme of heme biosynthesis
------------------------------------------|||||-||||--------------  1 [F] COG3072 Adenylate cyclase
------------------------------------------|||||-|||||--|----------  1 [T] COG3073 Negative regulator of sigma E activity
------------------------------------------|||||-|-||--------------  1 [S] COG3074 Uncharacterized protein conserved in bacteria
---|--------------------------------------|||||-|-||--------------  1 [E] COG3075 Anaerobic glycerol-3-phosphate dehydrogenase
------------------------------------------|||||-|-||--------------  1 [S] COG3076 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  1 [S] COG3078 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|||||-------------  1 [S] COG3079 Uncharacterized protein conserved in bacteria
---------------------------||-------------|||||-|-||--------------  1 [C] COG3080 Fumarate reductase subunit D
------------------------------------------|||||-||||--------------  1 [R] COG3081 Nucleoid-associated protein
------------------------------------------|||||-|-||--------------  1 [S] COG3082 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||--------------  1 [R] COG3083 Predicted hydrolase of alkaline phosphatase superfamily
------------------------------------------|||||-|-||--------------  1 [S] COG3084 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  1 [S] COG3085 Uncharacterized protein conserved in bacteria
-----------------|--|---------------------|||||-||||--------------  1 [T] COG3086 Positive regulator of sigma E activity
------------------------------------------|||||-||||||||----------  1 [D] COG3087 Cell division protein
------------------------------------------|||||-||||--------------  1 [S] COG3089 Uncharacterized protein conserved in bacteria
--------------------|-----|----------|----|--||-||||-------||--|--  1 [G] COG3090 TRAP-type C4-dicarboxylate transport system, small permease component
-------------------------------|||||||----|||||-||||--------------  1 [S] COG3091 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  1 [S] COG3092 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||-||-----------  1 [S] COG3094 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  1 [D] COG3095 Uncharacterized protein involved in chromosome partitioning
------------------------------------------|||||-|-||--------------  1 [D] COG3096 Uncharacterized protein involved in chromosome partitioning
------------------------------------------|||||-|-||--------------  1 [S] COG3097 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||--------------  1 [S] COG3098 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  1 [S] COG3099 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||--------------  1 [S] COG3100 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  1 [S] COG3101 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  1 [S] COG3102 Uncharacterized protein conserved in bacteria
-----------------------------------||-----|||||-||||--------------  1 [T] COG3103 SH3 domain protein
------------------------------------------|||||-||||--------------  1 [S] COG3105 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||-------||||---  1 [R] COG3106 Predicted ATPase
------------------------------------------|||||-|||||-------------  1 [R] COG3107 Putative lipoprotein
------------------------------------------|||||-|-||-------|||||--  1 [S] COG3108 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||--------------  1 [T] COG3109 Activator of osmoprotectant transporter ProP
------------------------------------------|||||-|-||--------------  1 [S] COG3110 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  1 [S] COG3112 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||||||----------  1 [R] COG3113 Predicted NTP binding protein (contains STAS domain)
------------------------------------------|||||-||||--------------  1 [U] COG3114 Heme exporter protein D
------------------------------------------|||||-|||||-------------  1 [D] COG3115 Cell division protein
------------------------------------------|||||||||||--|----------  1 [D] COG3116 Cell division protein
------------------------------------------|||||-||||||||----------  1 [S] COG3117 Uncharacterized protein conserved in bacteria
--------------------------||||------------|||||-|||||--|---|||||--  1 [O] COG3118 Thioredoxin domain-containing protein
------------------------------------------|||||-|-||--------------  1 [S] COG3120 Uncharacterized protein conserved in bacteria
------------------------------------------|||||--|--|-------------  1 [S] COG3122 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||-----|----------  1 [S] COG3123 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||----------------  1 [S] COG3124 Uncharacterized protein conserved in bacteria
----------------------------------||||----||||||-|--|--|---|-|||--  1 [C] COG3125 Heme/copper-type cytochrome/quinol oxidase, subunit 4
------------------------------------------|||||-||---------|-||---  1 [S] COG3126 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||-----|---|||||--  1 [Q] COG3127 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component
------------------------------------------|||----|--|---------||--  1 [S] COG3128 Uncharacterized iron-regulated protein
--------------|---------------------------|||||-||----------------  1 [R] COG3129 Predicted SAM-dependent methyltransferase
------------------------------------------|||||-||----------------  1 [J] COG3130 Ribosome modulation factor
------------------------------------------|||||-||------------|---  1 [S] COG3132 Uncharacterized protein conserved in bacteria
------------------------------------------|||||--|||---|----------  1 [M] COG3133 Outer membrane lipoprotein
------------------------------------------|||||--|--|-------------  1 [S] COG3134 Predicted outer membrane lipoprotein
---------------------|----|---------------|||-|-||----------|||---  1 [Q] COG3135 Uncharacterized protein involved in benzoate metabolism
------------------------------------------|||||-||------------|---  1 [R] COG3136 Uncharacterized membrane protein required for alginate biosynthesis
------------------------------------------|||||-|---|-------------  1 [M] COG3137 Putative salt-induced outer membrane protein
------------------------------------------|||||-||-------------|--  1 [E] COG3138 Arginine/ornithine N-succinyltransferase beta subunit
------------------------------------------|||||-||----------------  1 [S] COG3139 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  1 [S] COG3140 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||----------------  1 [S] COG3141 Uncharacterized protein conserved in bacteria
--------------------|----------|||-|------|||||-|--||------||-||--  1 [P] COG3142 Uncharacterized protein involved in copper resistance
------------------------------------------|||||-||-----|----------  1 [NT] COG3143 Chemotaxis protein
-----------------|------------|-----||----||||||||-----|----------  1 [N] COG3144 Flagellar hook-length control protein
--------------|----|------||||------------|||-|-||--|--|---|||||--  1 [L] COG3145 Alkylated DNA repair protein
------------------------------------------|||||-||--|--|----------  1 [S] COG3147 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||----------------  1 [S] COG3148 Uncharacterized conserved protein
------------------------------------------|-----||-----|----------  1 [U] COG3149 Type II secretory pathway, component PulM
------------------------------------------|||||-||--|-------------  1 [S] COG3151 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||-----|---|||----  1 [I] COG3154 Putative lipid carrier protein
------------------------------------------|||||-||----------------  1 [Q] COG3155 Uncharacterized protein involved in an early stage of isoprenoid biosynthesis
------------------------------------------|--|--||--|--|------||--  1 [U] COG3156 Type II secretory pathway, component PulK
------------------------------------------|||||-||-----|---|--|---  1 [S] COG3157 Hemolysin-coregulated protein (uncharacterized)
--|-----------------------|----||---------|||||-||--|--|---|||||--  1 [P] COG3158 K+ transporter
------------------------------------------|||||-||-||--|-------|--  1 [S] COG3159 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||----------------  1 [K] COG3160 Regulator of sigma D
|||-----||-----------------|||------------|||||-||-|-|||----------  1 [H] COG3161 4-hydroxybenzoate synthetase (chorismate lyase)
---------------------|----|---------|-----|||||--|--|-------------  1 [S] COG3162 Predicted membrane protein
------------------------------------------|||||-||--|--|----------  1 [S] COG3164 Predicted membrane protein
------------------------------------------|||||-||-|||||----------  1 [S] COG3165 Uncharacterized protein conserved in bacteria
------------------||----------------------|||||-||--||||------|---  1 [NU] COG3166 Tfp pilus assembly protein PilN
------------------------------------------|||||--|||-||-----------  1 [S] COG3171 Uncharacterized protein conserved in bacteria
---------------------------||--|----------|||||--|||--------------  1 [H] COG3172 Predicted ATPase/kinase involved in NAD metabolism
-------------------||-----|-------|-||----|||-|-||---------||-|---  1 [R] COG3180 Putative ammonia monooxygenase
--|---------------|-||----|---------------|||||-||-----||||||||---  1 [O] COG3187 Heat shock protein
----||-----|--------------|||-----|-------|||-|--|-----|---||||---  1 [S] COG3189 Uncharacterized conserved protein
----------------------||------------||----||||||||-----|----------  1 [N] COG3190 Flagellar biogenesis protein
--------------------|--------------||-----|||-|--|----------------  1 [E] COG3192 Ethanolamine utilization protein
----------||------|----------------|------|---|--|-----|---|-|||--  1 [R] COG3193 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol
-------------||---------------------------|||-|--|---------||||---  1 [F] COG3194 Ureidoglycolate hydrolase
---------------------------||-------------|------|----------------  1 [S] COG3196 Uncharacterized protein conserved in bacteria
--------------------------|----|||--------|||||--|||----||--------  1 [H] COG3201 Nicotinamide mononucleotide transporter
------------------|-----------------------|||-|--|----------------  1 [S] COG3204 Uncharacterized protein conserved in bacteria
---------------------|-----||-------------|||-|--|---------||-||--  1 [S] COG3214 Uncharacterized protein conserved in bacteria
---|---------------|----------------------|||||-||---------||-||--  1 [R] COG3217 Uncharacterized Fe-S protein
---|------|--------||-----|||--|--|--|----||||--||---------||-||--  1 [P] COG3221 ABC-type phosphate/phosphonate transport system, periplasmic component
-------------------------------|---||-----|||||--||---------------  1 [S] COG3223 Predicted membrane protein
---------------------------||-------------|||-|--|----------------  1 [S] COG3226 Uncharacterized protein conserved in bacteria
------------------||----------------------|||||--|-----|----------  1 [S] COG3228 Uncharacterized protein conserved in bacteria
-----------------|------------------------|||----|-----|----------  1 [S] COG3234 Uncharacterized protein conserved in bacteria
-------------------|-|----|---------------|------|----------------  1 [S] COG3236 Uncharacterized protein conserved in bacteria
-------------------|------|----||||||-----|||-|--|---------||-||--  1 [S] COG3237 Uncharacterized protein conserved in bacteria
-------------------|-|----|---||--||------|||-|--|-|-------|--|---  1 [S] COG3238 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||--|--|-----||---  1 [S] COG3242 Uncharacterized protein conserved in bacteria
--|----------------|-------||--|--||------||||---|-----|----|||---  1 [S] COG3247 Uncharacterized conserved protein
------------------------------------------|||-|-||----------------  1 [M] COG3248 Nucleoside-binding outer membrane protein
----||-----------------------------|||----|||||-----------|||||---  1 [S] COG3254 Uncharacterized conserved protein
---------------------|--------------------|||-|--|---------||||---  1 [R] COG3257 Uncharacterized protein, possibly involved in glyoxylate utilization
--------------------|----------------|----|||-|-||---------|--|---  1 [P] COG3263 NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain
------------------------------------------|||||-||----------------  1 [S] COG3266 Uncharacterized protein conserved in bacteria
------|||-----------------------||--------|||-|-|-----------------  1 [S] COG3270 Uncharacterized conserved protein
|-|---------------------------------------|||||-||----------------  1 [S] COG3272 Uncharacterized conserved protein
-------------------------------|----------|||||-|------|--------|-  1 [S] COG3274 Uncharacterized protein conserved in bacteria
-||-||---|-|----|-------------------------|||-|--|||------|-|-----  1 [J] COG3276 Selenocysteine-specific translation elongation factor
------------------------------------------|||||-||||--------------  1 [KE] COG3283 Transcriptional regulator of aromatic amino acids metabolism
-------------------|----------|-----||----|-----||-----|---|||||--  1 [QK] COG3284 Transcriptional activator of acetoin/glycerol metabolism
------------------||-------|-|------------|||||-||||-|||---|||||||  1 [C] COG3288 NAD/NADP transhydrogenase alpha subunit
-----------------------------------||-----|-||----|-|-|-----------  1 [S] COG3299 Uncharacterized homolog of phage Mu protein gp47
--------|-||------------------------------|||-|---||--------------  1 [P] COG3301 Formate-dependent nitrite reductase, membrane component
------------------------------------------|||-|---||------|-------  1 [P] COG3303 Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit
--------------------------|||-------------|||||-|--|-----------|--  1 [S] COG3304 Predicted membrane protein
-----------------||||---------|--||-------|||||-||||||||||-|||||||  1 [M] COG3307 Lipid A core - O-antigen ligase and related enzymes
------------------------------------------|||||-|---|--|----|||---  1 [K] COG3311 Predicted transcriptional regulator
------------------------------------------|||||-||||-||-----------  1 [C] COG3312 F0F1-type ATP synthase, subunit I
------------------------------------------|||||-||-----|----||||--  1 [R] COG3313 Predicted Fe-S protein
--------------------|---------|---|-||----|||-|-|-----------|-----  1 [S] COG3314 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||-|||----------  1 [M] COG3317 Uncharacterized lipoprotein
----------------------||------------|-----|||-|-||---||-----------  1 [R] COG3318 Predicted metal-binding protein related to the C-terminal domain of SecA
-------------------|------||||------|-----|||||--|-----|-----||---  1 [Q] COG3319 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases
-----------|---------------||--------|----|-----------------|-----  1 [K] COG3327 Phenylacetic acid-responsive transcriptional repressor
-------------------|||----|--------|||----|||-|---||--------------  1 [E] COG3340 Peptidase E
--|----------|----|||------||-|---|--|----|--||-||----------|-----  1 [L] COG3344 Retron-type reverse transcriptase
--|-|------|--|---------------|-----------|||||--|-|---|-------|--  1 [S] COG3384 Uncharacterized conserved protein
--|-|------|-------|-|--||-||-|-----||----|||-|--|-----|----|-|---  1 [S] COG3391 Uncharacterized conserved protein
-----------------------------------|-|----|||||-|------------||---  1 [S] COG3394 Uncharacterized protein conserved in bacteria
------------------|||----------------|----|--||---||-------||||---  1 [S] COG3395 Uncharacterized protein conserved in bacteria
----------------|--------------------|----|||-|------------|------  1 [G] COG3405 Endoglucanase Y
--------------------||---------|-|||-|----|||-----------------|---  1 [S] COG3412 Uncharacterized protein conserved in bacteria
------------------------------------------|||||||-------|||-------  1 [R] COG3417 Collagen-binding surface adhesin SpaP (antigen I/II family)
------------------------------------------||||||||----------------  1 [NUO] COG3418 Flagellar biosynthesis/type III secretory pathway chaperone
--|---------------------------------------||||---|-|-||----|-|||--  1 [S] COG3422 Uncharacterized conserved protein
------------------------------------------|||||---||--|-----------  1 [K] COG3423 Predicted transcriptional regulator
---------------------------||-------|-----|||||-||-----------|----  1 [Q] COG3433 Aryl carrier domain
-------------------------------||||-|-----|||-|------------|--|---  1 [R] COG3443 Predicted periplasmic or secreted protein
------------------------------------------|||||-|-||--------------  1 [R] COG3445 Acid-induced glycyl radical enzyme
------------------||----------------------|||-|--|----------|-|---  1 [T] COG3447 Predicted integral membrane sensor domain
-------------------|----------------------||||---|---------||||---  1 [P] COG3454 Metal-dependent hydrolase involved in phosphonate metabolism
-----------------|----------------|--|----|---|---------------|---  1 [E] COG3457 Predicted amino acid racemase
---------------------|---------------|----|------------|----|-----  1 [Q] COG3460 Uncharacterized enzyme of phenylacetate metabolism
-------------------------------|--|-------||||------------|-------  1 [S] COG3477 Predicted periplasmic/secreted protein
-------------------|----------------------|||-|--|--|--|---|--|---  1 [R] COG3500 Phage protein D
------------------------------||----||----|-----------------|--|--  1 [G] COG3507 Beta-xylosidase
--------------------|-----|---------------|||---|-|--|-|---||-||--  1 [R] COG3550 Uncharacterized protein related to capsule biosynthesis enzymes
--------------------------------||-|------|||-|--|--|--|---|||||--  1 [R] COG3568 Metal-dependent hydrolase
---------------------------------||-|-----|||||-------------|-|---  1 [E] COG3591 V8-like Glu-specific endopeptidase
--|----------------------------|---|------|||-----------------|---  1 [S] COG3592 Uncharacterized conserved protein
-||---------------|-|---------------------|||||-||-|-------|--|---  1 [L] COG3593 Predicted ATP-dependent endonuclease of the OLD family
------------------------------------------|||||-||---------|||||--  1 [T] COG3605 Signal transduction protein containing GAF and PtsI domains
|------------||-----|-----|||-|--|||-|----|||||-|-|||-----|-------  1 [S] COG3610 Uncharacterized conserved protein
---------------------------------|--------|||||---||-||-----------  1 [P] COG3615 Uncharacterized protein/domain, possibly involved in tellurite resistance
-------------------|----------------------||||---|---------||-|---  1 [P] COG3624 Uncharacterized enzyme of phosphonate metabolism
-------------------|----------------------||||---|---------||-|---  1 [P] COG3625 Uncharacterized enzyme of phosphonate metabolism
-------------------|----------------------||||---|---------||-|---  1 [P] COG3626 Uncharacterized enzyme of phosphonate metabolism
-------------------|----------------------||||---|---------||-|---  1 [P] COG3627 Uncharacterized enzyme of phosphonate metabolism
--------------------------------|---------|||||-||||-||---|-------  1 [E] COG3633 Na+/serine symporter
-------------------------------||-|-|-----|||-|--|--|--|-------|--  1 [O] COG3634 Alkyl hydroperoxide reductase, large subunit
---|---------------||-----|----|--|--|-|--||||---|---------||-||--  1 [P] COG3638 ABC-type phosphate/phosphonate transport system, ATPase component
------------------------------------------|||---|--|--------------  1 [S] COG3647 Predicted membrane protein
--|-----------|------|--------------------|||-|----|-|||--|----|--  1 [L] COG3663 G:T/U mismatch-specific DNA glycosylase
-|------------------|---------------------|||-|---|---------------  1 [S] COG3681 Uncharacterized conserved protein
--------------------------------||||------|||-|---------------|---  1 [G] COG3684 Tagatose-1,6-bisphosphate aldolase
------------------------------------------|||-----|--|---------|--  1 [S] COG3692 Uncharacterized protein conserved in bacteria
--------------|------|----|||--|---|------|||||-||----------------  1 [L] COG3695 Predicted methylated DNA-protein cysteine methyltransferase
----------------|-||----------------------|||-|--|-----|||--|--|--  1 [P] COG3696 Putative silver efflux pump
--------------------|-----------|---------|||-|-|-|---------------  1 [HI] COG3697 Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase)
---------------------|--------------------|||--------------||||---  1 [S] COG3698 Predicted periplasmic protein
--------------------------------|---------|||-|---|---------------  1 [R] COG3700 Acid phosphatase (class B)
-------------||---------------------|-----|||----------|---|||||--  1 [P] COG3703 Uncharacterized protein involved in cation transport
------------------------------------------||||---|---------||||---  1 [P] COG3709 Uncharacterized component of phosphonate metabolism
------------------------------------------|------|-----|---||--|--  1 [PT] COG3712 Fe2+-dicitrate sensor, membrane component
---------------------------||-------------|||||-|------|-----|||--  1 [S] COG3714 Predicted membrane protein
------------------------------------||----|||||------------||--|--  1 [G] COG3717 5-keto 4-deoxyuronate isomerase
------------------------------------------|||-|---||-------|||||--  1 [J] COG3719 Ribonuclease I
-------------------------------||-||||----|||---------------------  1 [L] COG3723 Recombinational DNA repair protein (RecE pathway)
------------------------------------------|||||--|-------------|--  1 [E] COG3724 Succinylarginine dihydrolase
------------------------------------------|||||--|--|-------------  1 [V] COG3725 Membrane protein required for beta-lactamase induction
------------------------------------------|||||-||-|--------------  1 [R] COG3726 Uncharacterized membrane protein affecting hemolysin expression
------------------------------------------|||-|-------||----|--|--  1 [L] COG3727 DNA G:T-mismatch repair endonuclease
-------------------|----------------|-----|||-|--|-------------|--  1 [R] COG3729 General stress protein
-----------------------------------|-|----|||-|----|----------|---  1 [G] COG3730 Phosphotransferase system sorbitol-specific component IIC
-----------------------------------|-|----|||-|----|----------|---  1 [G] COG3731 Phosphotransferase system sorbitol-specific component IIA
-----------------------------------|-|----||--|----|----------|---  1 [G] COG3732 Phosphotransferase system sorbitol-specific component IIBC
-----------|--|----|-|--------------------|-------------------|---  1 [Q] COG3733 Cu2+-containing amine oxidase
------------------------------------------|---|--------|---|||||--  1 [G] COG3734 2-keto-3-deoxy-galactonokinase
------------------------|-----|-----------|||||-|----------|||||--  1 [S] COG3735 Uncharacterized protein conserved in bacteria
------------------------------------------|||-|--|-|-----------|--  1 [S] COG3738 Uncharacterized protein conserved in bacteria
------------------------------------------|||----|-----|----|||---  1 [S] COG3753 Uncharacterized protein conserved in bacteria
-------------------|-|--------------------|||-|--|---------||-||--  1 [S] COG3755 Uncharacterized protein conserved in bacteria
------------------------------------------|---------|---------|---  1 [S] COG3756 Uncharacterized protein conserved in bacteria
------------------------------||||--------|||-------|------||||---  1 [M] COG3757 Lyzozyme M1 (1,4-beta-N-acetylmuramidase)
--------------------|-----------|---------||||---|-----|---||||---  1 [S] COG3758 Uncharacterized protein conserved in bacteria
------------------------------------||----|||-|--------|---|---|--  1 [S] COG3766 Predicted membrane protein
------------------------------------------|||||---||-------||||---  1 [S] COG3768 Predicted membrane protein
------||----|-----------------------------|||-|-------------------  1 [R] COG3769 Predicted hydrolase (HAD superfamily)
------------------------------------------|||||---||-------||||---  1 [M] COG3770 Murein endopeptidase
------------------------------------------|||||-|-||--------------  1 [S] COG3771 Predicted membrane protein
------------------------------------------|||||-||----------------  1 [S] COG3776 Predicted membrane protein
------------------------------------------|-||----|--||-----------  1 [S] COG3778 Uncharacterized protein conserved in bacteria
------------------------------------------|----------||-------|---  1 [S] COG3779 Uncharacterized protein conserved in bacteria
------------------||----------------------|||-|--------|------|---  1 [S] COG3781 Predicted membrane protein
------------------------------------------|||||-|--|--------------  1 [C] COG3783 Soluble cytochrome b562
------------------------------------------|||||--|-------------|--  1 [S] COG3784 Uncharacterized protein conserved in bacteria
------------------------------------------|||||------------|||||--  1 [S] COG3785 Uncharacterized conserved protein
------------------------------------------|||||----|------|-------  1 [S] COG3787 Uncharacterized protein conserved in bacteria
-------------------|----------------------|||||-|--------------|--  1 [R] COG3788 Uncharacterized relative of glutathione S-transferase, MAPEG superfamily
------------------------------------------|||-|--|-------------|--  1 [S] COG3789 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|--|--------------  1 [S] COG3790 Predicted membrane protein
----------------|-------------|----|||----|||-|--|-----|----------  1 [KT] COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
----|--|--||-----|---|---------|||||||-|--|||||-|-----------------  1 [G] COG3833 ABC-type maltose transport systems, permease component
------------------------------|-----||----|||||-|||---------------  1 [KT] COG3835 Sugar diacid utilization regulator
------------------------------------------|||||-|-||-------||||---  1 [H] COG3840 ABC-type thiamine transport system, ATPase component
------------------------------------------|||-|-|--|--------------  1 [T] COG3851 Signal transduction histidine kinase, glucose-6-phosphate specific
------------------------------------------|||||-||--|--|---|||||--  1 [T] COG3852 Signal transduction histidine kinase, nitrogen specific
------------------|-----------------------|||||--|-----|---|||----  1 [R] COG3895 Predicted periplasmic protein
------------------------------------------|||||-|-||--------------  1 [L] COG3923 Primosomal replication protein N''
------------------------------------------|||||---||--------------  1 [S] COG3924 Predicted membrane protein
------------------------------------------|||||---||--------------  1 [G] COG3925 N-terminal domain of the phosphotransferase system fructose-specific component IIB
------------------------|-----------------||||||||-----|----------  1 [MNO] COG3951 Rod binding protein
------------------------------------------|||||-|-----------|-----  1 [C] COG3954 Phosphoribulokinase
------------------------------------------|||-|--|-----|----|-|---  1 [R] COG3960 Glyoxylate carboligase
-------------------------------||--|------|||-|--|-----|----------  1 [R] COG3969 Predicted phosphoadenosine phosphosulfate sulfotransferase
---------------------|-----||-------------|||||--|-|---|---|-|-|--  1 [Q] COG3971 2-keto-4-pentenoate hydratase
-------------------|----------------------|||||-|----||-----------  1 [E] COG3977 Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase
------------------------------------------|||||-|--||-------------  1 [S] COG3978 Acetolactate synthase (isozyme II), small (regulatory) subunit
--|----------------|-------------|--------|||-|--------|----------  1 [V] COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
----------------|-------------------------||||||||||||||||||||||||  1 [R] COG4105 DNA uptake lipoprotein
---------------------|-----||-------------||||---|---------||||---  1 [R] COG4106 Trans-aconitate methyltransferase
-------------------|----------------------||||---|---------||-|---  1 [P] COG4107 ABC-type phosphonate transport system, ATPase component
------------------||-|----|---||||||------||||||||||||||---|||||--  1 [J] COG4108 Peptide chain release factor RF-3
-------------------------------------|----|||||-------------|-----  1 [R] COG4114 Uncharacterized Fe-S protein
-------------------|----------------------|||-|--|-----|-----||---  1 [C] COG4117 Thiosulfate reductase cytochrome B subunit (membrane anchoring protein)
||--------------|-||-|---|----------------|||||-||||---|--|||--|--  1 [S] COG4121 Uncharacterized conserved protein
----------------||--|---------||||||||||--|||||-|-||----||||||||--  1 [R] COG4123 Predicted O-methyltransferase
------------------------------------------|||||-|||||------|||||||  1 [O] COG4133 ABC-type transport system involved in cytochrome c biogenesis, ATPase component
------------------------------------------||||--|----------|||----  1 [R] COG4134 ABC-type uncharacterized transport system, periplasmic component
------------------------------------------|||---|-----------|-----  1 [R] COG4135 ABC-type uncharacterized transport system, permease component
------------------------------------------|||---|-----------|-----  1 [R] COG4136 ABC-type uncharacterized transport system, ATPase component
------------------------------------------|||||-||-|||||----------  1 [R] COG4137 ABC-type uncharacterized transport system, permease component
------------------------------------------|||||-|-----------------  1 [H] COG4138 ABC-type cobalamin transport system, ATPase component
------------------------------------------|||||-|-----------------  1 [H] COG4139 ABC-type cobalamin transport system, permease component
---|--||--|----------|--|-----------------|||||-|-||-||----||||---  1 [H] COG4143 ABC-type thiamine transport system, periplasmic component
--------|-----------|----|----------------|||||---||--------------  1 [H] COG4145 Na+/panthothenate symporter
-------------------------------------|----|||-----||--------------  1 [R] COG4146 Predicted symporter
--------|-------|--|-|----|---------||----|||||-||--|--|----------  1 [R] COG4147 Predicted symporter
----------------------------------|-------|||||-||||-------||||---  1 [P] COG4148 ABC-type molybdate transport system, ATPase component
--|---------|---|-||------|||-----||||----|||||-||||---|||||||||--  1 [P] COG4149 ABC-type molybdate transport system, permease component
------------------------------------------|||||-|----------|-||---  1 [P] COG4150 ABC-type sulfate transport system, periplasmic component
---------------------------------|--------|||-|---|--------||||---  1 [G] COG4154 Fucose dissimilation pathway protein FucU
------------------------------------------|||||-|-||--------------  1 [E] COG4161 ABC-type arginine transport system, ATPase component
------------------------------------------|||||-|-||--------------  1 [V] COG4167 ABC-type antimicrobial peptide transport system, ATPase component
------------------------------------------|||||-|-||--------------  1 [V] COG4168 ABC-type antimicrobial peptide transport system, permease component
------------------------------------------|||||-|-||--------------  1 [V] COG4170 ABC-type antimicrobial peptide transport system, ATPase component
------------------------------------------|||||-|-||--------------  1 [V] COG4171 ABC-type antimicrobial peptide transport system, permease component
--------------------|---------------------|||||-||-----|---||||---  1 [R] COG4172 ABC-type uncharacterized transport system, duplicated ATPase component
------------------------------------------|||||-||-----|||-||||---  1 [R] COG4174 ABC-type uncharacterized transport system, permease component
--|----------------------|-----||--||-----|||||--|-----|---||||---  1 [E] COG4175 ABC-type proline/glycine betaine transport system, ATPase component
--|----------------------|-----||--||-----|||||--|-----|---||||---  1 [E] COG4176 ABC-type proline/glycine betaine transport system, permease component
-|------|-|||----|||||----|------|---|----|||||--|-----|--|||||---  1 [E] COG4177 ABC-type branched-chain amino acid transport system, permease component
-------------|----||-------|||------------|||-----||-|-|---||||---  1 [R] COG4178 ABC-type uncharacterized transport system, permease and ATPase components
------------------------------------------|||||-||-----|---||-||--  1 [Q] COG4181 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component
------------------------------------------|||-------|------|------  1 [S] COG4197 Uncharacterized protein conserved in bacteria, prophage-related
------------------------------------------|||||-||-----|-----|-|--  1 [H] COG4206 Outer membrane cobalamin receptor protein
------------------||-------||--------|----|||||-||--||||---|||||--  1 [P] COG4208 ABC-type sulfate transport system, permease component
--------------------|---|-----------------|||||-|-||--------------  1 [G] COG4211 ABC-type glucose/galactose transport system, permease component
-------------------------------------|-|--||||----|----|---||||---  1 [G] COG4213 ABC-type xylose transport system, periplasmic component
-------------------------------------|-|--||||----|----|---||||---  1 [G] COG4214 ABC-type xylose transport system, permease component
---|---------||---||||----|||--|-|||------|||-|-||||||||||||||----  1 [R] COG4221 Short-chain alcohol dehydrogenase of unknown specificity
------------------------------------------|||||--|-|-|||---|||||--  1 [C] COG4230 Delta 1-pyrroline-5-carboxylate dehydrogenase
----------------------||------------------|||||-||||||||--|----|--  1 [OC] COG4232 Thiol:disulfide interchange protein
-----|-----|---------------||-------------|||---------------------  1 [C] COG4237 Hydrogenase 4 membrane component (E)
-------------------------|----------------|||||-||-----|||-||||---  1 [R] COG4239 ABC-type uncharacterized transport system, permease component
-------------------|----------------------||||----------|---------  1 [R] COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain
-------------------|-|--------------------|||---------------------  1 [R] COG4248 Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains
------------------------------------------|||-|--------|----|-|---  1 [P] COG4256 Hemin uptake protein
--|------------------|-----------|--------|--|------------|-------  1 [V] COG4268 McrBC 5-methylcytosine restriction system component
---------------------|--------------------|||||--------|---||-----  1 [S] COG4269 Predicted membrane protein
--------------------|---------|----|------|||-|--|-----|----------  1 [E] COG4302 Ethanolamine ammonia-lyase, small subunit
--------------------|---------|----|------|||-|--|-----|----------  1 [E] COG4303 Ethanolamine ammonia-lyase, large subunit
--------------------|---------------------|||||--|---------|------  1 [V] COG4452 Inner membrane protein involved in colicin E2 resistance
------------------------------------------||||---|----------|-|---  1 [P] COG4521 ABC-type taurine transport system, periplasmic component
------------------------------------------||||---|---------||-|---  1 [P] COG4525 ABC-type taurine transport system, ATPase component
--------------------------|||-----|-------|||--------------||||---  1 [S] COG4529 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||-------|||----  1 [P] COG4531 ABC-type Zn2+ transport system, periplasmic component/surface adhesin
------------------------------------------||||||||||||||----------  1 [P] COG4535 Putative Mg2+ and Co2+ transporter CorC
----------------------------------|-------|||||-||||---|----||||||  1 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB
------------------------------------------|||||-||----------------  1 [K] COG4568 Transcriptional antiterminator
---------------------------||-------------|||----------|----------  1 [Q] COG4569 Acetaldehyde dehydrogenase (acetylating)
----------------|--------------||-|||-----|||---------------------  1 [L] COG4570 Holliday junction resolvase
------------------------------------------|||||------------|--|---  1 [M] COG4571 Outer membrane protease
-------------------|----------------------|||-|------------------|  1 [R] COG4572 Putative cation transport regulator
------------------------------------------|||||--|---------------|  1 [R] COG4574 Serine protease inhibitor ecotin
------------------|||--------------|------|||-|-------------------  1 [QC] COG4576 Carbon dioxide concentrating mechanism/carboxysome shell protein
--------------------------||||-------|----|||-|----|----------|---  1 [K] COG4578 Glucitol operon activator
------------------------------------------|||||--|-----|----------  1 [T] COG4579 Isocitrate dehydrogenase kinase/phosphatase
------------------------------------------|||||-|------|----------  1 [S] COG4582 Uncharacterized protein conserved in bacteria
--------------------|---------------------||||--||-|--------|-----  1 [R] COG4589 Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase
------------------------------------------|||||-||----------------  1 [P] COG4592 ABC-type Fe2+-enterobactin transport system, periplasmic component
----------------------------------|-|-----|--------|--------------  1 [P] COG4594 ABC-type Fe3+-citrate transport system, periplasmic component
-------------------|----------------------|||---|----------||||---  1 [E] COG4597 ABC-type amino acid transport system, permease component
------------------------------------------|||||-||---------||-|---  1 [E] COG4598 ABC-type histidine transport system, ATPase component
------------------------------------------|||-|--|-----|--|-------  1 [QP] COG4615 ABC-type siderophore export system, fused ATPase and permease components
----------------------------------|-------|||-|--------|----------  1 [R] COG4619 ABC-type uncharacterized transport system, ATPase component
------------------------------------------|||||-||||--------------  1 [M] COG4623 Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein
------------------------------||--||------|||-----------------|---  1 [R] COG4626 Phage terminase-like protein, large subunit
--|----------------------------|----------|||||-|--|----------|---  1 [CH] COG4635 Flavodoxin
------------------------------------------|||-|--|-----|----------  1 [KT] COG4650 Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain
------------------------------------------|||||-||--|--|----|||---  1 [P] COG4651 Kef-type K+ transport system, predicted NAD-binding component
--|--------------|--|---||---------|------||||||||||--------------  1 [C] COG4656 Predicted NADH:ubiquinone oxidoreductase, subunit RnfC
--|--------------|--|---------------------||||||||||--------------  1 [C] COG4657 Predicted NADH:ubiquinone oxidoreductase, subunit RnfA
--|--------------|--|---|-----------------||||||||||--------------  1 [C] COG4658 Predicted NADH:ubiquinone oxidoreductase, subunit RnfD
--|--------------|--|---------------------||||||||||--------------  1 [C] COG4659 Predicted NADH:ubiquinone oxidoreductase, subunit RnfG
--|--------------|--|---------------------||||||||||--------------  1 [C] COG4660 Predicted NADH:ubiquinone oxidoreductase, subunit RnfE
--------------------|-----|---|-----------|||||-|--|--------------  1 [R] COG4667 Predicted esterase of the alpha-beta hydrolase superfamily
---||-----|-|-------|-------------||-|----|||-|--------|----|||---  1 [I] COG4670 Acyl CoA:acetate/3-ketoacid CoA transferase
------------------------------------------|||----|-----|----------  1 [S] COG4676 Uncharacterized protein conserved in bacteria
------------------------------|-----------|||||--------|----------  1 [G] COG4677 Pectin methylesterase
-------------------|----------------------|||-|-------------|-|---  1 [S] COG4680 Uncharacterized protein conserved in bacteria
------------------------------------------|||||--|-----|----------  1 [S] COG4681 Uncharacterized protein conserved in bacteria
------------------------------------------|||----|-----|----------  1 [S] COG4685 Uncharacterized protein conserved in bacteria
------------------------------|||---------|||----------|---|-|||--  1 [S] COG4695 Phage-related protein
------------------||----------------------|||-|---------||--------  1 [S] COG4735 Uncharacterized protein conserved in bacteria
--------------------------|---------------|||-----------------|---  1 [S] COG4763 Predicted membrane protein
--------------------|--------------|------|||-|------------|------  1 [E] COG4766 Ethanolamine utilization protein
------------------------------------------|------|------||--|--|--  1 [P] COG4772 Outer membrane receptor for Fe3+-dicitrate
------------------------------------------|||||--|---||-----------  1 [P] COG4773 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid
------------------------------------------|||----|--|----------|--  1 [P] COG4774 Outer membrane receptor for monomeric catechols
-------------||-||||||||||----------------||||||||||||||||||||||||  1 [M] COG4775 Outer membrane protein/protective antigen OMA87
------------------------------------------|||||||-||--------------  1 [K] COG4776 Exoribonuclease II
-------------------|----------------------||||---|---------||-|---  1 [P] COG4778 ABC-type phosphonate transport system, ATPase component
--------------------------|---------------|||||-||---------|------  1 [P] COG4779 ABC-type enterobactin transport system, permease component
----------------|-||----------------------|||||-||--|--|-----|||--  1 [R] COG4783 Putative Zn-dependent protease, contains TPR repeats
------------------------------------------|||||-|-||--------------  1 [R] COG4785 Lipoprotein NlpI, contains TPR repeats
----------------||------||----|----|||----||||||||-----|||||||||--  1 [N] COG4786 Flagellar basal body rod protein
------------------------------------------||||||||-----|----------  1 [N] COG4787 Flagellar basal body rod protein
----------------||||----------------------|||||-||||||||----------  1 [U] COG4796 Type II secretory pathway, component HofQ
--|-----------------|---------------------|||-|--------|---------|  1 [S] COG4804 Uncharacterized conserved protein
-----------------------------------|||----|||||-------------------  1 [G] COG4806 L-rhamnose isomerase
--------------------|---------------------|||||--|----------------  1 [S] COG4807 Uncharacterized protein conserved in bacteria
----------------------------------||------|||-|-------------------  1 [S] COG4808 Uncharacterized protein conserved in bacteria
--------------------|--------------|------|||-|-------------------  1 [E] COG4810 Ethanolamine utilization protein
-----------------------------------|------|||||----|--------------  1 [S] COG4811 Predicted membrane protein
--------------------|--------------|------|||-|-------------------  1 [E] COG4812 Ethanolamine utilization cobalamin adenosyltransferase
--------------------|--------------|------|||-|-------------------  1 [E] COG4816 Ethanolamine utilization protein
--------------------|--------------|------|||-|-------------------  1 [E] COG4819 Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition
--------------------|--------------|------|||-|-------------------  1 [E] COG4820 Ethanolamine utilization protein, possible chaperonin
--------------------|--------------|------|-----------------------  1 [S] COG4884 Uncharacterized protein conserved in bacteria
--------------------|--------------|------|||-|-------------------  1 [E] COG4917 Ethanolamine utilization protein
--------------------|---------------------|||||-|||||||----|||||--  1 [D] COG4942 Membrane-bound metallopeptidase
--------------------------|---------------|||||--------|---||-----  1 [S] COG4950 Uncharacterized protein conserved in bacteria
-------------------||---------------------|||-|----||------||-||-|  1 [M] COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC
------------------------------------------|||||-||--||||----------  1 [NU] COG4967 Tfp pilus assembly protein PilV
----------------|-------------------------|||||-||||||||----------  1 [NU] COG4969 Tfp pilus assembly protein, major pilin PilA
------------------------------------------|||||-||||||||----------  1 [L] COG4973 Site-specific recombinase XerC
--------------------|---|-|||||---||||----|||||-||||||||---|||||||  1 [L] COG4974 Site-specific recombinase XerD
-------------------------------|--||||----|||||-|-||-------|-|-|--  1 [CO] COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components
--------------------|-----|||--||-||||----|||||-|-||-------|-|-|--  1 [CO] COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components
------------------------------|--|||||----|||||-|----------|--|---  1 [R] COG4989 Predicted oxidoreductase
------------------------------------------|||-|--|---------||-|---  1 [G] COG4993 Glucose dehydrogenase
------------------------------------------|||||-|-----------------  1 [T] COG4999 Uncharacterized domain of BarA-like signal transduction histidine kinases
---------------------|----|---------------|||||-||-----|------||--  1 [R] COG5006 Predicted permease, DMT superfamily
------------------------------------------||||||||||||||----------  1 [K] COG5007 Predicted transcriptional regulator, BolA superfamily
----------------|-------||----------------|||||-||||||||---|||||||  1 [M] COG5009 Membrane carboxypeptidase/penicillin-binding protein
---------------------------||-------------|||||-------------||----  1 [S] COG5383 Uncharacterized protein conserved in bacteria
------------------------------------------|||||--|-----|----------  1 [S] COG5393 Predicted membrane protein
------------------------------------------|||||--|----------------  1 [D] COG5404 SOS-response cell division inhibitor, blocks FtsZ ring formation
----------------||-------|--------||||----|||||||||||--|||||||||||  1 [O] COG5405 ATP-dependent protease HslVU (ClpYQ), peptidase subunit
------------------------------------------|||----|-----|----------  1 [S] COG5445 Predicted secreted protein
------------------------------------------|||-|--------|---|||||--  1 [S] COG5455 Predicted integral membrane protein
------------------------------------------|||-|--|---------||||---  1 [S] COG5457 Uncharacterized conserved small protein
------------------------------------------|||-|------------|--|---  1 [S] COG5475 Uncharacterized small protein
-------------------|----------------------|||-|-------------|-|---  1 [K] COG5499 Predicted transcription regulator containing HTH domain
------------------------------------------|||---------------|-|---  1 [S] COG5507 Uncharacterized conserved protein
--------------------------|---------------|||----|-----|----------  1 [Q] COG5517 Small subunit of phenylpropionate dioxygenase
-------------------|---------------|------|||-|-----|--|----------  1 [R] COG5525 Bacteriophage tail assembly protein
------------------------------------------|---------||------------  1 [S] COG5532 Uncharacterized conserved protein
------------------------------------------|||||--|-----|----------  1 [R] COG5544 Predicted periplasmic lipoprotein
---|----|---------------------------------|||-|-------------------  1 [C] COG5557 Polysulphide reductase
------------------------------------------||-||--|-----------|----  1 [N] COG5567 Predicted small periplasmic lipoprotein
------------------------------------------|||----------|---||-----  1 [S] COG5569 Uncharacterized conserved protein
------------------------------------------|||-|--|-||-------------  1 [N] COG5571 Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion
-----------------|------------|-----||----|||||--|----------------  1 [M] COG5581 Predicted glycosyltransferase
------------------------------------------|||||-|-||--------------  1 [R] COG5633 Predicted periplasmic lipoprotein
||||||||||||||--||||-|--------||--|-||--------|-||------||-||-||--  0 [E] COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase
||||----|||||||-||||||||||||||||||||||||||---|---|---|||||||||||||  0 [J] COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases
||||----||--------||----------|----|----------|---|----------|----  0 [P] COG0310 ABC-type Co2+ transport system, permease component
---|||----||-||||-||-|||--||||||||||||||||-|-|--|||||--||--|--|---  0 [RTKL] COG0515 Serine/threonine protein kinase
|||-||--||-|-||--||--|----|||--|---|||-------|---||-||||---|||||--  0 [S] COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit
||||--||||-||----|||||----||||||||||||||||-||-|---|--------|||----  0 [P] COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters
-------------||---||-------------------------|--|-||-|||---|||||--  0 [O] COG0678 Peroxiredoxin
-----------------|||||----|||||-----||-------|-||||||--|||||||||--  0 [E] COG0757 3-dehydroquinate dehydratase II
|-||--|||-|-|---|||||||||-||||||||||||-------||--|||-||---|||-|-||  0 [P] COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin
--------------|---||-|----|||-----|-|||----|||---||----|||-||||---  0 [E] COG0804 Urea amidohydrolase (urease) alpha subunit
--------------|---||-|----|-------|--||----||----||----|||-||||---  0 [O] COG0829 Urease accessory protein UreH
--------------|---||-|----|||-----|--||----|||---||----|||-||||---  0 [O] COG0830 Urease accessory protein UreF
--------------|---||-|----|||-----|-|||----|||---||----|||-||||---  0 [E] COG0831 Urea amidohydrolase (urease) gamma subunit
--------------|---||-|----|||-----|-|||----|||---||----|||--|||---  0 [E] COG0832 Urea amidohydrolase (urease) beta subunit
-|||||----|----------|---||---|-----|-|----||-|---|---|-|||----|--  0 [V] COG1002 Type II restriction enzyme, methylase subunits
||||||--||||------|||------||-|----|----------|--|-----|---||||---  0 [H] COG1010 Precorrin-3B methylase
---|----|-|-|||||-|||---||||||---------------|--||||--------------  0 [I] COG1022 Long-chain acyl-CoA synthetases (AMP-forming)
|||---|||||||---|-||-|----||||||-|-|||-------|--||-----|---|||||-|  0 [F] COG1051 ADP-ribose pyrophosphatase
||||--|||||||----|||||--|-||||||||||||||||-||-|-|-|----|---|||----  0 [P] COG1122 ABC-type cobalt transport system, ATPase component
--|-----|-------|-||------|||||||-||||--------|-||-||||---|-||||||  0 [GM] COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component
|||---||||||-||----|-|----|||-------||-----||---------------|-----  0 [R] COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
|||||||||||||||||-||-|----|||||-----||-------||--|--||||--||||||--  0 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)
|--||||-|--|-|---|--||-----||-|-|-|-||-------||-||-----|---|||||--  0 [Q] COG1228 Imidazolonepropionase and related amidohydrolases
--||--|-|-|--||-|----|||--||||----||||-------|---------|-------|--  0 [H] COG1232 Protoporphyrinogen oxidase
|||---||||-------|------------|---------------|-------------------  0 [R] COG1237 Metal-dependent hydrolases of the beta-lactamase superfamily II
|-||--||--|-|---|||||||||||||-||||||||-----||||-||-----|------||--  0 [R] COG1266 Predicted metal-dependent membrane protease
|||||||||||||-----||||-----||-|----|-|--------|-||-----|---||||---  0 [H] COG1270 Cobalamin biosynthesis protein CobD/CbiB
|-|||||||||||||||-||-|-----||--------------||||--|-----|----------  0 [R] COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily
----------------------||---------------------|--||||-||-----------  0 [C] COG1347 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD
----------------|----|||-||||-||--||||-------|--||||--------------  0 [M] COG1388 FOG: LysM repeat
--||----|-|-|||||-||||----|||||-||--||||------|-||--||||--|||-|---  0 [O] COG1404 Subtilisin-like serine proteases
||||--|||||||------------|----|--------------|---------|----------  0 [F] COG1437 Adenylate cyclase, class 2 (thermophilic)
-|||--|----------|-||-----|---|----|--||---|||--|--|--|-|||-------  0 [S] COG1479 Uncharacterized conserved protein
-||---|||-||------||-|-----||-----------------|---|-|--|---||-||-|  0 [R] COG1487 Predicted nucleic acid-binding protein, contains PIN domain
||||||--||-|------||||-----||-|----|-|--------|-||-----|---|||||--  0 [H] COG1492 Cobyric acid synthase
--||||||----|---||--||-----||------|||--------|--|-----|---|||||--  0 [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold
-------------||--|--------|---|-|||-||-----||---|--|---|---|------  0 [G] COG1621 Beta-fructosidases (levanase/invertase)
|-||||||||--|---------------------|--------||-|-|----------||-|---  0 [R] COG1661 Predicted DNA-binding protein with PD1-like DNA-binding motif
----------------------||||----|-----|--------|--||--|--||||----|--  0 [M] COG1664 Integral membrane protein CcmA involved in cell shape determination
|||---||--||-----||||------------------------|------------|-------  0 [R] COG1672 Predicted ATPase (AAA+ superfamily)
--|-----|-------|-||------|||||||-||||--------|-||-||||---|-||||||  0 [GM] COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component
|-|-------------||--|---------|----|||--------|-||-----|---||-|---  0 [S] COG1683 Uncharacterized conserved protein
-||--------------|--|---|-------||-|--||---|||---|-|---|---|||||--  0 [S] COG1704 Uncharacterized conserved protein
|||---|||||||---||------------|---|-----------|---|--------||----|  0 [R] COG1708 Predicted nucleotidyltransferases
||||||||||||||||-----|-----------------------|---|----------------  0 [TD] COG1718 Serine/threonine protein kinase involved in cell cycle control
--|--------------|||-------------------------|-----------|--|-||--  0 [N] COG1724 Predicted periplasmic or secreted lipoprotein
----------------------||---------------------|--||||-||-----------  0 [C] COG1726 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA
---|--||----|-------|----|----|---|-||-------||-|-||-||-|||-------  0 [C] COG1757 Na+/H+ antiporter
|||-----||-----------------------------------|--------------------  0 [S] COG1795 Uncharacterized conserved protein
||||||--||||------||||-----||-|----|-|--------|--|-----|---||||---  0 [H] COG1797 Cobyrinic acid a,c-diamide synthase
------------------||--||---------------------|--||||-||-------|---  0 [C] COG1805 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB
|||------|---|----|--|-----||||-----|------||||-||------------|---  0 [GC] COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
--|----------------|||----||||-||||||------||-|--||-||||---|||||-|  0 [I] COG1835 Predicted acyltransferases
--||------|-|-----|||-----|-----|||--|-----||||-||||||||--|||||---  0 [P] COG1840 ABC-type Fe3+ transport system, periplasmic component
--|----------||----||----|--------------------|--|-----||||----|--  0 [F] COG1864 DNA/RNA endonuclease G, NUC1
------||---------|------------|--|--||-------|------|-------|--|--  0 [G] COG1874 Beta-galactosidase
------------------||----||----||||-|||-------|--|-|||-------------  0 [M] COG1876 D-alanyl-D-alanine carboxypeptidase
------|||--------|--|---|-------|-------------|-|--|--------------  0 [C] COG1883 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit
|||-||--||||------|||---------|----|----------|--|-----|---|-|----  0 [H] COG1903 Cobalamin biosynthesis protein CbiD
-|||--|||||||---||-|-------------|||-------||-----------||--------  0 [S] COG1912 Uncharacterized conserved protein
||||||||--||----|||||-----||--|||--|||-------||--|-----||||||||---  0 [S] COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain
||||----|----------|---------------|----------|-------------------  0 [P] COG1930 ABC-type cobalt transport system, periplasmic component
------||---|--------||-----||---|||-||-------|---------|----------  0 [O] COG2039 Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)
|||||||||||||-------------||--|--------------|---|-|---|---||-||--  0 [NU] COG2064 Flp pilus assembly protein TadC
||-|||--||||------|||---------|----|----------|--|-----|---||||---  0 [H] COG2073 Cobalamin biosynthesis protein CbiG
||||||--||||------|||------||-|----|----------|--|-----|---||||---  0 [H] COG2082 Precorrin isomerase
---||||||-|||-------||----||||-----|||--------|--|-----|---|||||--  0 [S] COG2096 Uncharacterized conserved protein
||----------------|||------||-|----|----------|--|-----|---||||---  0 [H] COG2099 Precorrin-6x reductase
--|---|||---------|-----------------|---------|--------|---||-|---  0 [GR] COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzymes
--|---||----|---||-----------------|---------|--------------------  0 [G] COG2152 Predicted glycosylase
-----|--|-----------|-----|------|-|--||------|---|||-|-||-|--|---  0 [L] COG2189 Adenine specific DNA methylase Mod
----------------------||---------------------|--||||-||-----------  0 [C] COG2209 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE
|||-----|||-------------------|---------------|-------------------  0 [C] COG2221 Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits
---|||-----|-------------|-||--|||||----|-----|-||----------|-|---  0 [E] COG2235 Arginine deiminase
|----------------||||-|||||||-|---|-||||-----|--||--|||----|||||||  0 [P] COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain)
||||||--||||------|||-----|||-|----|----------|--|-----|---||||---  0 [H] COG2241 Precorrin-6B methylase 1
||||||--||||------|||-----|||-|----|----------|--|---------||||---  0 [H] COG2242 Precorrin-6B methylase 2
||||||--||||------|||------||-|----|----------|--|-----|---||||---  0 [H] COG2243 Precorrin-2 methylase
--------------|------|----|||-|---|-|---------|--------|-------|--  0 [I] COG2272 Carboxylesterase type B
------------------||----------||-|--||||||-||||-||--||||----|-||--  0 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
------------------|--|--------|-----|------|||--------------------  0 [T] COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1
---|--||--|||-------||-------------|||-------|--|-------------|--|  0 [E] COG2317 Zn-dependent carboxypeptidase
----||------------||-|----||||-------|-------|--|-----------------  0 [K] COG2345 Predicted transcriptional regulator
-------------||------|-----||--|---|---------|---|-----|---|---|--  0 [T] COG2365 Protein tyrosine/serine phosphatase
--------|-||---------|--------------||-------||--|-|--------------  0 [Q] COG2368 Aromatic ring hydroxylase
-|-------------------|-------------|--------|-----|-|||-----------  0 [S] COG2369 Uncharacterized protein, homolog of phage Mu protein gp30
------------------||-|----|-------|--||----|||---||----|||-||||---  0 [O] COG2371 Urease accessory protein UreE
------||||--|--------------------------------|--------------------  0 [R] COG2401 ABC-type ATPase fused to a predicted acetyltransferase domain
|-||||--|||||||-----------|-------|----------|---|-----|---||||---  0 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog
||----||-|---------|-------------------------|---|---||----|-|----  0 [S] COG2510 Predicted membrane protein
--||||--|--||||-||||||----|---|||-|||||-------|--|||-|||||-|||----  0 [P] COG2608 Copper chaperone
---------------------|--------|--|--|------||-|--|---|----||---|--  0 [R] COG2819 Predicted hydrolase of the alpha/beta superfamily
------------------|||----------------------|||---|||||||--|----|--  0 [U] COG2831 Hemolysin activation/secretion protein
-------------------|-|------------||--------|-----|--||-----------  0 [R] COG2842 Uncharacterized ATPase, putative transposase
--------------------|-||------------|--------||--|---||---|-------  0 [S] COG2849 Uncharacterized protein conserved in bacteria
------------------|------|-----------------||---|---------|-------  0 [S] COG2859 Uncharacterized protein conserved in bacteria
---------------------|-----------------------|--||-|-||||||-|-----  0 [C] COG2863 Cytochrome c553
----------------------||---------------------|--||||-||-----------  0 [C] COG2869 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC
----------------------||---------------------|--||||-||-----------  0 [C] COG2871 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF
||||||--||||------|||------||-|----|----------|--|-----|---||||---  0 [H] COG2875 Precorrin-4 methylase
------------------||--------------------------|-|---|||-----||-|--  0 [S] COG2929 Uncharacterized protein conserved in bacteria
----------------|-||-------------------------|--||--||||---||-||--  0 [Q] COG2931 RTX toxins and related Ca2+-binding proteins
--------------------|----------||-|--------|--|--||||||----|||||--  0 [K] COG2932 Predicted transcriptional regulator
---------------------|---------|-|-----------|---|--|---|||----|--  0 [E] COG2957 Peptidylarginine deiminase and related enzymes
---|||--------------||----------|-|-||-------||-||-----|---|||||--  0 [E] COG2986 Histidine ammonia-lyase
---|||--------------||----------|-|-||-------|--||-----|---|||||--  0 [E] COG2987 Urocanate hydratase
---------------------------------------------|--||||-||-----------  0 [S] COG2991 Uncharacterized protein conserved in bacteria
------------------------------|--------------|--||--|-------------  0 [S] COG3007 Uncharacterized paraquat-inducible protein B
------------------||--------------|-||-------|--||--|--|------||--  0 [S] COG3011 Uncharacterized protein conserved in bacteria
--|---------------|------------|--|-|---------|-|----------|-||---  0 [M] COG3049 Penicillin V acylase and related amidases
---------------------------------------------|--||||||||----------  0 [NU] COG3063 Tfp pilus assembly protein PilF
--||------------|--||-----|-----|-||-------|||---|-|-|||||-||-|--|  0 [S] COG3177 Uncharacterized conserved protein
---------------------|------------------------|--||---------|-----  0 [R] COG3179 Predicted chitinase
--------------------|-----|---------||--------|-||-|---|---||-----  0 [S] COG3181 Uncharacterized protein conserved in bacteria
--|------------------|------------------------|-||------------|---  0 [V] COG3183 Predicted restriction endonuclease
-------------------|-------||||-----||-------|---|-----|---|--|---  0 [Q] COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis
------------------|||----------------------|||---|||||||--|----|--  0 [U] COG3210 Large exoproteins involved in heme utilization or adhesion
---------------------|-----------------------||-||-|---|-----|----  0 [E] COG3232 5-carboxymethyl-2-hydroxymuconate isomerase
-------------------|--------------------------|-||-||--|----------  0 [IR] COG3240 Phospholipase/lecithinase/hemolysin
---------------------------||-------|------|--|--|-----|---|------  0 [S] COG3251 Uncharacterized protein conserved in bacteria
---------------------------||-----------------|-||----------------  0 [U] COG3267 Type II secretory pathway, component ExeA (predicted ATPase)
-----------|-------|-|----|||-----------------|--|-----|----|-----  0 [G] COG3280 Maltooligosyl trehalose synthase
------------------|-----------------|---------|--|-----|---||-||--  0 [T] COG3300 MHYT domain (predicted integral membrane sensor domain)
---------------------------------------------|----||-||-||-|-||--|  0 [M] COG3306 Glycosyltransferase involved in LPS biosynthesis
-|-|----|-------|---------|-------||---------|------|--------|||--  0 [L] COG3316 Transposase and inactivated derivatives
-------------------|------|||||-----|--------|---------|---||-|---  0 [Q] COG3321 Polyketide synthase modules and related proteins
--|-----|------------------------------------|--||----------|--|--  0 [T] COG3322 Predicted periplasmic ligand-binding sensor domain
--|-----------------------|||--------|--------|-||-|---|---|||||--  0 [R] COG3324 Predicted enzyme related to lactoylglutathione lyase
---|---------|---------------------|-|--------|-|-----------------  0 [G] COG3325 Chitinase
--|----------------------------|||-|||--------|--|---||-|--|------  0 [S] COG3326 Predicted membrane protein
--|-||-----|------|--------||-||-----||----||||--------|----|-|---  0 [L] COG3328 Transposase and inactivated derivatives
--------------------|-----|----------|--------|-||-|---|---||-----  0 [S] COG3333 Uncharacterized protein conserved in bacteria
--|--|--|--|------||-|----|------|---|-----||-|-------||----|-|---  0 [L] COG3335 Transposase and inactivated derivatives
-----------------|---------------|---|-------|--|-----------------  0 [G] COG3345 Alpha-galactosidase
----|-------------|-----------------||-------|-------------||-|---  0 [S] COG3347 Uncharacterized conserved protein
--|-||----|------|-|-------------------------|-----|------|-------  0 [S] COG3350 Uncharacterized conserved protein
----|------|--|------------||-----|----------||--------|||--------  0 [P] COG3376 High-affinity nickel permease
---|-------|-------|------|||--||--|-------|||------|--|----------  0 [R] COG3378 Predicted ATPase
---------||||-----------------|||---||--------|--|-----|------|---  0 [S] COG3382 Uncharacterized conserved protein
----||-----|-|-------|------------|-|---------|--|-||--|---|||||--  0 [G] COG3386 Gluconolactonase
-------------------------------|---|-|-------|--||----------------  0 [S] COG3397 Uncharacterized protein conserved in bacteria
-----------------------------------------------|-|--|--|---|------  0 [S] COG3416 Uncharacterized protein conserved in bacteria
||||||||||||||||---------|-----||||||--------|-----------------|--  0 [I] COG3425 3-hydroxy-3-methylglutaryl CoA synthase
-----------|--------------|----------|-----||-|--|-----|----------  0 [Q] COG3435 Gentisate 1,2-dioxygenase
--||-|---------------|----------||---------|||-------------||||---  0 [L] COG3436 Transposase and inactivated derivatives
--||||-----|----|-------|---------------------|------||------|----  0 [S] COG3439 Uncharacterized conserved protein
-----|-------------|-|---------------------||--------||-----------  0 [V] COG3440 Predicted restriction endonuclease
-----------------|-|--------------------------|--|---------||-|---  0 [R] COG3450 Predicted enzyme of the cupin superfamily
---|--------------------------|--------|------|-----|--|||-|||||||  0 [U] COG3451 Type IV secretory pathway, VirB4 components
-------------------------------------------||||-||-----|---|--|---  0 [S] COG3455 Uncharacterized protein conserved in bacteria
-------------------------------------------|||--||---------|--|---  0 [T] COG3456 Uncharacterized conserved protein, contains FHA domain
-----------------|------------|----|---------|--|----------||||---  0 [G] COG3459 Cellobiose phosphorylase
|-|||--------------|||--------||-----|--------|------|||----|||---  0 [R] COG3467 Predicted flavin-nucleotide-binding protein
--------------------|---|--------------------|-----|------|--|----  0 [P] COG3470 Uncharacterized protein probably involved in high-affinity Fe2+ transport
--------------------------|------------------|---|-----|---|||||||  0 [Q] COG3485 Protocatechuate 3,4-dioxygenase beta subunit
---|----------|----|-----------------|-------|---|-----|----|-|---  0 [Q] COG3486 Lysine/ornithine N-monooxygenase
--------------|------------------------------|---|-----|--|---||--  0 [R] COG3491 Isopenicillin N synthase and related dioxygenases
--------------------|----------||---||--------|-|-----------------  0 [C] COG3493 Na+/citrate symporter
-------------------|-----------------------||||--|--|--|---|--|---  0 [R] COG3497 Phage tail sheath protein FI
-------------------------------------------||-|--|--|--|----------  0 [R] COG3498 Phage tail tube protein FII
-------------------------------------------||-|--|--|--|---|------  0 [R] COG3499 Phage protein U
-------------------|-----------------------||||-||-----|---|--|---  0 [S] COG3501 Uncharacterized protein conserved in bacteria
-------------------|----------|---------------|-----|--|||-||-|-||  0 [U] COG3505 Type IV secretory pathway, VirD4 components
---------------------------------------------||-----|||----||-|---  0 [S] COG3514 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  0 [S] COG3515 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  0 [S] COG3516 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  0 [S] COG3517 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  0 [S] COG3518 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  0 [S] COG3519 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  0 [S] COG3520 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|------|---  0 [S] COG3521 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  0 [S] COG3522 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  0 [S] COG3523 Uncharacterized protein conserved in bacteria
-------------------------------------------||-|-|-------||--------  0 [S] COG3528 Uncharacterized protein conserved in bacteria
-------------------------------------------|-||-||----------------  0 [R] COG3529 Predicted nucleic-acid-binding protein containing a Zn-ribbon domain
-------------------------------------------|-||-||-----|----------  0 [S] COG3530 Uncharacterized protein conserved in bacteria
---------------------------------------------|--||-----|------|---  0 [O] COG3531 Predicted protein-disulfide isomerase
-----------------|-------------------|-----||-|------------||-||--  0 [S] COG3533 Uncharacterized protein conserved in bacteria
----------|--------|----------|-----||-----||-|--|----------------  0 [P] COG3546 Mn-containing catalase
--|--------|-------||-----||||--||---|-------|---|---||----||-||--  0 [L] COG3547 Transposase and inactivated derivatives
-------------------|--------------------------|--|--|--|-----||---  0 [O] COG3555 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases
------------------------------|||-|--------||-----|---|-----------  0 [K] COG3561 Phage anti-repressor protein
-------------------|-|---------|-|-----------|--|----------|--||--  0 [S] COG3575 Uncharacterized protein conserved in bacteria
--|----------------------------------------||-----|-----||---|----  0 [S] COG3586 Uncharacterized conserved protein
--------------------|-------------------------|----|-||-||--------  0 [V] COG3587 Restriction endonuclease
------||----------------------||---|||-------|--------------------  0 [S] COG3595 Uncharacterized conserved protein
-||||||||-|||------|-------||--------------||||-----|--|---||-||--  0 [K] COG3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain
-------------------------------||--|-------|||---||-|--------|----  0 [K] COG3617 Prophage antirepressor
---------------------------------------------|---|-----|--|||||---  0 [R] COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold
-------------------|-------------------------||--|--|--|------|---  0 [R] COG3628 Phage baseplate assembly protein W
------|||---------------|---------------------|-|--|--------------  0 [C] COG3630 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit
---------------------------------------------|----|-|--|----|--|--  0 [K] COG3636 Predicted transcriptional regulator
-------------------------------||-|||------|||--------------------  0 [S] COG3645 Uncharacterized phage-encoded protein
-------------------------------|-|-||------||-----||--------------  0 [S] COG3646 Uncharacterized phage-encoded protein
-------------------|-------------|-----|-----||-||---|-------|-|--  0 [R] COG3654 Prophage maintenance system killer protein
-------------------|-------------------------|----|-|--|----|--|--  0 [S] COG3657 Uncharacterized protein conserved in bacteria
-------------------|-|-----||--------------|||--||--|--|---|||||--  0 [R] COG3668 Plasmid stabilization system protein
---------------------|---------------------||--------||-----------  0 [S] COG3680 Uncharacterized protein conserved in bacteria
--------------------|---|--------------------||---||-------||||---  0 [R] COG3683 ABC-type uncharacterized transport system, periplasmic component
--------------------------|--------|||-------||--------|---|||||--  0 [G] COG3718 Uncharacterized enzyme involved in inositol metabolism
-------------------------------------------|||---|-----|----|-|---  0 [P] COG3720 Putative heme degradation protein
-------------------------------------------|||--|--|-------|------  0 [P] COG3721 Putative heme iron utilization protein
-------------------------------||-|||------|||---|------------|---  0 [L] COG3728 Phage terminase, small subunit
---------------------------||--|---|-------||-|--------|---|---|--  0 [R] COG3740 Phage head maturation protease
---------------------|-----------------------|---|---------|||||--  0 [E] COG3741 N-formylglutamate amidohydrolase
---------------------------||-||-----------||---------------------  0 [L] COG3747 Phage terminase, small subunit
--------------|-------------------------------|--|-----|---|||||--  0 [S] COG3791 Uncharacterized conserved protein
------------------||-|---------------------|||-------------|---|--  0 [P] COG3793 Tellurite resistance protein
---|---------------------------------------||-----------------|---  0 [E] COG3799 Methylaspartate ammonia-lyase
----------------------------------------------|--|----------|-||--  0 [S] COG3811 Uncharacterized protein conserved in bacteria
--------------------------------||-----------|---------|--|----|--  0 [S] COG3817 Predicted membrane protein
--------------------------------||-----------|---------|--|----|--  0 [S] COG3819 Predicted membrane protein
------------------------------------|------|||-----|---------||---  0 [R] COG3822 ABC-type sugar transport system, auxiliary component
---------------------|----|-----|------------|-----------------|--  0 [O] COG3823 Glutamine cyclotransferase
-----------------|------------|-----||-------|--------------------  0 [G] COG3867 Arabinogalactan endo-1,4-beta-galactosidase
---------------------------------------------||--------|---|||||--  0 [S] COG3892 Uncharacterized protein conserved in bacteria
---------------------------------------------|---|--|-------------  0 [R] COG3907 PAP2 (acid phosphatase) superfamily protein
---------------------------------------------|---|-----|---||-|---  0 [TQ] COG3916 N-acyl-L-homoserine lactone synthetase
----------------------------------------------|--|---------||||---  0 [S] COG3921 Uncharacterized protein conserved in bacteria
----------------------------------------------|------||-----|||---  0 [R] COG3926 Putative secretion activating protein
------------------------------|----||---------|-------------------  0 [K] COG3933 Transcriptional antiterminator
------------------------------|------|--------|-------------------  0 [R] COG3940 Predicted beta-xylosidase
--------------------------------------------||--|||---------------  0 [R] COG3941 Mu-like prophage protein
---------------------------------------------||--|---||-----------  0 [R] COG3943 Virulence protein
----------------------------------------------|--|--|--|----------  0 [R] COG3948 Phage-related baseplate assembly protein
----------------------------------------------|-|-----------|-----  0 [R] COG3950 Predicted ATP-binding protein involved in virulence
-|--||-|--|||----|--|------------|-----------||------------||-|---  0 [G] COG3958 Transketolase, C-terminal subunit
-|--||-|--|||----|--|------------|-----------||------------||-|---  0 [G] COG3959 Transketolase, N-terminal subunit
--|----------||------------|||||--|-----------|-------------------  0 [GHR] COG3961 Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes
--------------------------|--------|||-------||--------|---|||||--  0 [E] COG3962 Acetolactate synthase
-------------------------------------|-------|-------------||||---  0 [I] COG3963 Phospholipid N-methyltransferase
----------------------------------------------|------------|--|---  0 [R] COG3964 Predicted amidohydrolase
-------------------------------------|-------|--|----------||-----  0 [P] COG3965 Predicted Co/Zn/Cd cation transporters
-----------|---------------------------------|-------------||-||--  0 [R] COG3970 Fumarylacetoacetate (FAA) hydrolase family protein
----------------------------------------------|--|--|------|------  0 [R] COG3972 Superfamily I DNA and RNA helicases
---|---------------------------|---|-|-------||-||----------------  0 [R] COG3979 Uncharacterized protein contain chitin-binding domain type 3
-----------------|---------------------------|-----|--------|-----  0 [R] COG4099 Predicted peptidase
--|----------------|-------------------------|--||-----|---|--|---  0 [S] COG4104 Uncharacterized conserved protein
---------------------|--------|------------|||--------------------  0 [R] COG4110 Uncharacterized protein involved in stress response
---------------------------------------------||--|-----|---||-----  0 [S] COG4125 Predicted membrane protein
--|---------------------------|---------------|----------------|--  0 [S] COG4127 Uncharacterized conserved protein
---------------------------------------------|--||----------------  0 [R] COG4128 Zonula occludens toxin
----------------------------------------------|--------|---||-|---  0 [G] COG4130 Predicted sugar epimerase
-------------------------------------------|||-----|----------|---  0 [R] COG4158 Predicted ABC-type sugar transport system, permease component
----------------------------------------------|-|--|--------------  0 [T] COG4192 Signal transduction histidine kinase regulating phosphoglycerate transport system
------------------||-|-----------------------|------------|||-|---  0 [S] COG4222 Uncharacterized protein conserved in bacteria
------------------------------|-----||-------||------------|------  0 [R] COG4225 Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
-------------------|-|---------------------||-------|--|----|----|  0 [S] COG4226 Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters
--------------------------------------------||----|--||-----------  0 [R] COG4228 Mu-like prophage DNA circulation protein
----------------------||----------------------|------------|||||--  0 [OC] COG4233 Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis
---------------------------------------------|---|-----|----------  0 [S] COG4253 Uncharacterized protein conserved in bacteria
-------------------------------------------||-------|--|----------  0 [R] COG4258 Predicted exporter
---------------------------------------------|---|---|||----------  0 [S] COG4259 Uncharacterized protein conserved in bacteria
-------------------------------------------||-------|--|----------  0 [R] COG4261 Predicted acyltransferase
---|---------------|--------------|--|-------|---------|----|-----  0 [Q] COG4264 Siderophore synthetase component
-----------------|----------------------------|-----|--|----------  0 [R] COG4287 PhoPQ-activated pathogenicity-related protein
-----------------|---------------------------|-------------||-----  0 [S] COG4289 Uncharacterized protein conserved in bacteria
------------------------------|--------------|-------||-----------  0 [S] COG4304 Uncharacterized protein conserved in bacteria
------------------------------||-------------|----------------|---  0 [S] COG4331 Predicted membrane protein
------------------------------|---------------|------------|--|---  0 [S] COG4332 Uncharacterized protein conserved in bacteria
----------------------------------|--------||---------------|-----  0 [S] COG4333 Uncharacterized protein conserved in bacteria
---------------------|----------------------|-----|---------------  0 [R] COG4373 Mu-like prophage FluMu protein gp28
--------------------------------------------||----|--||-----------  0 [R] COG4379 Mu-like prophage tail protein gpP
---------------------------------------------|---|---|||----------  0 [S] COG4380 Uncharacterized protein conserved in bacteria
--------------------------------------------||----|--||-----------  0 [S] COG4381 Mu-like prophage protein gp46
--------------------------------------------|-----|--||-----------  0 [S] COG4382 Mu-like prophage protein gp16
--------------------------------------------|-----|--||-----------  0 [S] COG4383 Mu-like prophage protein gp29
--------------------------------------------||----|--||-----------  0 [S] COG4384 Mu-like prophage protein gp45
----------------------------------------------|--|--|--|---|------  0 [R] COG4385 Bacteriophage P2-related tail formation protein
--------------------------------------------||----|--||-----------  0 [R] COG4386 Mu-like prophage tail sheath protein gpL
--------------------------------------------|-----|--||-----------  0 [S] COG4387 Mu-like prophage protein gp36
--------------------------------------------|-----|--||-----------  0 [R] COG4388 Mu-like prophage I protein
--------------------|------------------------|-----|------|-------  0 [S] COG4393 Predicted membrane protein
--------------------------------------------|-----|---|-----------  0 [R] COG4396 Mu-like prophage host-nuclease inhibitor protein Gam
--------------------------------------------|-----|---|-----------  0 [R] COG4397 Mu-like prophage major head subunit gpT
------------------------------||-|-|||-----|-||-------------------  0 [S] COG4405 Uncharacterized protein conserved in bacteria
----------------------------------|--|-------|---|----------------  0 [S] COG4408 Uncharacterized protein conserved in bacteria
--------------------------|------|------------|-|--|--------------  0 [G] COG4409 Neuraminidase (sialidase)
----------------------------------|----------|---|-----------|----  0 [E] COG4413 Urea transporter
------------------------------|-------------|-----|---------------  0 [R] COG4416 Mu-like prophage protein Com
-------------------|--------------------------|-||----------------  0 [FJ] COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA
---------------------------||--------------||-|-|-|-|--|----|-----  0 [S] COG4453 Uncharacterized protein conserved in bacteria
---------------------------------------------||--|---------|------  0 [R] COG4455 Protein of avirulence locus involved in temperature-dependent protein secretion
------------------|---------------------------|---|-|-------|-||--  0 [S] COG4456 Virulence-associated protein and related proteins
---------------------------------------------||----|----------|---  0 [S] COG4457 Uncharacterized protein conserved in bacteria, putative virulence factor
---------------------------------------------||----|----------|---  0 [S] COG4458 Uncharacterized protein conserved in bacteria, putative virulence factor
----------------------------------------------|--|------------|---  0 [S] COG4460 Uncharacterized protein conserved in bacteria
---------------------------||----------------||--|---------|--|---  0 [S] COG4461 Uncharacterized protein conserved in bacteria, putative lipoprotein
---------------------------------------------|---|--|-------------  0 [S] COG4517 Uncharacterized protein conserved in bacteria
--------------------------------------------|---|-|---------------  0 [S] COG4518 Mu-like prophage FluMu protein gp41
---------------------------------------------|--||----------------  0 [S] COG4519 Uncharacterized protein conserved in bacteria
---------------------------------------------||--|--|--|----------  0 [R] COG4540 Phage P2 baseplate assembly protein gpV
------------------------------|----|----------|---------------|---  0 [Q] COG4542 Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase
---------------------------------------------|-------------|||||--  0 [H] COG4547 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase)
---------------------|----|----------------|||--||-|-------||-|---  0 [P] COG4558 ABC-type hemin transport system, periplasmic component
---------------------|----|----------------|||--||---------||-|---  0 [P] COG4559 ABC-type hemin transport system, ATPase component
----------------------------------------------|--|-|---|---|||||--  0 [T] COG4566 Response regulator
--|------------------------||-----||-|-----|||---------|---||-|---  0 [L] COG4584 Transposase and inactivated derivatives
-------------------------------------------||---|---------|-|-----  0 [R] COG4588 Accessory colonization factor AcfC, contains ABC-type periplasmic domain
---------------------------------------------|--||----------------  0 [R] COG4590 ABC-type uncharacterized transport system, permease component
--------------------------|------||-||-------|--|----||---||-|----  0 [P] COG4604 ABC-type enterochelin transport system, ATPase component
--------------------------|------||-||-------|--|----||---||-|----  0 [P] COG4605 ABC-type enterochelin transport system, permease component
--------------------------|------||-||-------|--|----||---||-|----  0 [P] COG4606 ABC-type enterochelin transport system, permease component
--------------------------|------||-||-------|--|----||---||-|----  0 [P] COG4607 ABC-type enterochelin transport system, periplasmic component
----------------|----------------------------|---|---------||-||||  0 [R] COG4618 ABC-type protease/lipase transport system, ATPase and permease components
---------------------|-----------------------|--|-----------------  0 [S] COG4628 Uncharacterized conserved protein
-------------------------------------------||||-----|--|----------  0 [S] COG4643 Uncharacterized protein conserved in bacteria
---------------------|--------|--------------|-------------|--|---  0 [L] COG4644 Transposase and inactivated derivatives, TnpA family
-------------------------------------------||---------||----------  0 [S] COG4648 Predicted membrane protein
---------------------------||--------------||----------|---|--||--  0 [R] COG4653 Predicted phage phi-C31 gp36 major capsid-like protein
----------------------||-------------------||||--|-----|------|---  0 [U] COG4669 Type III secretory pathway, lipoprotein EscJ
-------------------------------------------||||--|-----|----------  0 [S] COG4672 Phage-related protein
------------------||-|----|----------|-------|---|-----|---||-|---  0 [R] COG4674 Uncharacterized ABC-type transport system, ATPase component
------------------||-----------------------||----------|----------  0 [G] COG4678 Muramidase (phage lambda lysozyme)
-------------------|-------------|---------||||---|-|-------------  0 [S] COG4679 Phage-related protein
-------------------|-------||----------------|--------------------  0 [S] COG4683 Uncharacterized protein conserved in bacteria
-------------------------------------------||------|---|----------  0 [S] COG4688 Uncharacterized protein conserved in bacteria
--|----------------------------||-------------|--|----------------  0 [E] COG4690 Dipeptidase
----------------------------------------------|---------||-||-----  0 [G] COG4692 Predicted neuraminidase (sialidase)
---------------------------------------------|---|-----|----------  0 [Q] COG4693 Oxidoreductase (NAD-binding), involved in siderophore biosynthesis
-------------------------------------------||----------|-------|--  0 [S] COG4700 Uncharacterized protein conserved in bacteria containing a divergent form of TPR repeats
---------------------------------------------|--|-||--------------  0 [S] COG4701 Uncharacterized protein conserved in bacteria
-------------||------------------------------|--------------|||---  0 [S] COG4702 Uncharacterized conserved protein
-------------------------------------------||--------|-|----------  0 [I] COG4706 Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase
----------------------------------------------|----|---|----------  0 [S] COG4714 Uncharacterized membrane-anchored protein conserved in bacteria
-------------------------------------------||||--|-----|----------  0 [S] COG4718 Phage-related protein
-------------------------------------------||||--|-----|----------  0 [S] COG4723 Phage-related protein, tail component
----------------------------------------------|-----|--|----------  0 [S] COG4727 Uncharacterized protein conserved in bacteria
-------------------------------------------||||--|-----|----------  0 [S] COG4733 Phage-related protein, tail component
-------------------|-------------------------|-------------|------  0 [R] COG4734 Antirestriction protein
-------------------|-----------------------||-|------|||----|-----  0 [S] COG4737 Uncharacterized protein conserved in bacteria
----------------------||-------------------||||--|-----|------|---  0 [U] COG4789 Type III secretory pathway, component EscV
-------------------------------------------||||--|-----|------|---  0 [U] COG4790 Type III secretory pathway, component EscR
----------------------||-------------------||||--|-----|------|---  0 [U] COG4791 Type III secretory pathway, component EscT
-------------------------------------------||||--|------------|---  0 [U] COG4792 Type III secretory pathway, component EscU
----------------------||-------------------||||--|-----|------|---  0 [U] COG4794 Type III secretory pathway, component EscS
--------------------|---------|----|----------|-------------------  0 [H] COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase
---|----------------|----------------------||---------------------  0 [E] COG4865 Glutamate mutase epsilon subunit
-----------------|-----------------|----------|-------------------  0 [Q] COG4869 Propanediol utilization protein
----------------------------------------------|-|------------|----  0 [S] COG4890 Predicted outer membrane lipoprotein
----------------------------------------------|--|-----------|----  0 [S] COG4893 Uncharacterized protein conserved in bacteria
-----------------------------------|----------|---------------|---  0 [Q] COG4909 Propanediol dehydratase, large subunit
-----------------------------------|----------|---------------|---  0 [Q] COG4910 Propanediol dehydratase, small subunit
--------------------------|------------------|------|-------------  0 [S] COG4913 Uncharacterized protein conserved in bacteria
--------------------------|------------------|------|-------------  0 [S] COG4924 Uncharacterized protein conserved in bacteria
-|---------------|-|-|----|-------------------|------------|------  0 [R] COG4928 Predicted P-loop ATPase
--|----------------||------------------------|-----|---------|----  0 [S] COG4929 Uncharacterized membrane-anchored protein
--|-------|-----------------------------------|-------------------  0 [O] COG4930 Predicted ATP-dependent Lon-type protease
------------------------------|----|----------|-------------------  0 [TK] COG4936 Predicted sensor domain
--------------------------|------|---------||---------------------  0 [S] COG4951 Uncharacterized protein conserved in bacteria
---------------------------------------------|---|-|---|---||-||--  0 [OU] COG4960 Flp pilus assembly protein, protease CpaA
---------------------------------------------|---|-|---|---||-||--  0 [U] COG4961 Flp pilus assembly protein TadG
||----||-|----------------|||-|--------------|---|-||--|---||-||--  0 [U] COG4962 Flp pilus assembly protein, ATPase CpaF
---------------------------------------------|---|-|---|---||-||--  0 [U] COG4963 Flp pilus assembly protein, ATPase CpaE
--------------------------|||----------------|---|-|---|---||-||--  0 [U] COG4965 Flp pilus assembly protein TadB
-------------------------------------------||----|-----|---|||||--  0 [K] COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain
--------------------|------------------------|-----|--------------  0 [S] COG4984 Predicted membrane protein
---------------------------------------------|--||----------------  0 [P] COG4985 ABC-type phosphate transport system, auxiliary component
--------------------------------------------|-----|--||-----------  0 [R] COG5003 Mu-like prophage protein gp37
----------------------------------------------|--|--|--|----------  0 [R] COG5004 P2-like prophage tail protein X
--------------------------------------------|-----|---|-----------  0 [R] COG5005 Mu-like prophage protein gpG
---------------------------------------------|---|-|---|---||-||--  0 [U] COG5010 Flp pilus assembly protein TadD, contains TPR repeats
|||---|-|-------||--|---|-------|-------------|-||-|------|-------  0 [C] COG5016 Pyruvate/oxaloacetate carboxyltransferase
-------------||------------------------------|--------------------  0 [T] COG5212 Low-affinity cAMP phosphodiesterase
-------------||------------------------------|---------|---|||||||  0 [O] COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components
--|--------------|---------------------------|--------------------  0 [S] COG5276 Uncharacterized conserved protein
-------------------------------------------||||--|-----|---|-|----  0 [S] COG5281 Phage-related minor tail protein
------------------------------||---|-------||-|-----|-------------  0 [S] COG5283 Phage-related tail protein
--|-----------------|----------------|-----||||---||||||----|||---  0 [UW] COG5295 Autotransporter adhesin
----------------------------------------------|--|-----|----------  0 [R] COG5301 Phage-related tail fibre protein
---------------------------||--------------||-|-------------|-|---  0 [R] COG5302 Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid
------||----------||-------|||----------------|-------------------  0 [S] COG5305 Predicted membrane protein
---------------------------------------------|---|-----|---||-|---  0 [S] COG5373 Predicted membrane protein
---------------------------------------------|---------|------||--  0 [S] COG5419 Uncharacterized conserved protein
----------------------------------------------|------------|--|---  0 [S] COG5426 Uncharacterized membrane protein
---------------------------------------------|---|-----|---|--|--|  0 [S] COG5430 Uncharacterized secreted protein
-------------------------------------------||||--|-----|----------  0 [S] COG5435 Uncharacterized conserved protein
---------------------------------------------|--------------|||---  0 [S] COG5441 Uncharacterized conserved protein
-------------------------------------|-------|-------------|---|--  0 [S] COG5460 Uncharacterized conserved protein
-------------------------------------------||-|-----|------|------  0 [S] COG5471 Uncharacterized conserved protein
---------------------------------------------|---------|--|-------  0 [S] COG5472 Predicted small integral membrane protein
-------------------------------------------|-||--|-----|---||||---  0 [S] COG5487 Small integral membrane protein
------------------------------|----||------||||-------------------  0 [N] COG5492 Bacterial surface proteins containing Ig-like domains
-------------------------------------------|--|--------|-----|-|-|  0 [S] COG5510 Predicted small secreted protein
-------------------------------------------||-|-----|--|----------  0 [R] COG5511 Bacteriophage capsid protein
-----------------------------------||---------|--------|----------  0 [R] COG5518 Bacteriophage capsid portal protein
--|-------------------------------|--------||||----|--------------  0 [L] COG5519 Superfamily II helicase and inactivated derivatives
------------------------------|-----|---------|----------------|--  0 [M] COG5520 O-Glycosyl hydrolase
--|------------------------------------------|-----------------|--  0 [R] COG5529 Pyocin large subunit
---------------------------------------------|--------------|-|---  0 [S] COG5556 Uncharacterized conserved protein
---------------------------------------------|--------------|-|---  0 [R] COG5564 Predicted TIM-barrel enzyme, possibly a dioxygenase
--------------------------------------------|-|-|-|---------------  0 [S] COG5566 Uncharacterized conserved protein
-------------------|-----------------------||-|-----|-------------  0 [S] COG5606 Uncharacterized conserved small protein
----------------------------------------------|----------||-------  0 [R] COG5610 Predicted hydrolase (HAD superfamily)
-------------------------------------------||||--|----------------  0 [S] COG5613 Uncharacterized conserved protein
------------------------------|------------||----------|---|------  0 [R] COG5614 Bacteriophage head-tail adaptor
---------------------------------------------|--------------|||---  0 [R] COG5618 Predicted periplasmic lipoprotein
---------------------------------------------|--------------|-|---  0 [S] COG5642 Uncharacterized conserved protein
---------------------------||----------------|--------------|-|---  0 [S] COG5654 Uncharacterized conserved protein