(Pae) Pseudomonas aeruginosa Functional categories Fun All J A K L B D Y V T M N Z W U O C G E F H I P Q R S COGs 2,241 144 2 85 100 1 27 -  23 87 121 73 -  -  90 103 155 96 204 66 125 59 154 52 286 362 proteins 4,893 200 2 520 159 3 33 -  73 428 270 156 -  -  176 195 338 258 601 107 193 248 381 217 763 495 Distribution of COGs by number of proteins proteins 1 2 3 4 5 6 7 8 9 10 11 12 13 14 16 17 18 19 20 21 24 26 28 29 30 32 34 37 40 45 49 54 70 121 COGs 1470 372 165 67 44 26 20 11 14 7 5 4 5 1 2 2 4 1 1 4 2 1 1 1 2 1 1 1 1 1 1 1 1 1

Co-ocurrences in sister taxa No sister genomes in order Pseudomonadales

++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
||------||------|-||||----||||||||||||----|||||-||||||||--||||||-- 121 [K] COG0583 Transcriptional regulator
||||||||||||||||||||||||||||||||||||||-||||||||||||||||||||||||||| 70 [GEPR] COG0477 Permeases of the major facilitator superfamily
-----------------||||-----|||-||-|||||----|||||-||||||||--||||||-- 54 [K] COG2207 AraC-type DNA-binding domain-containing proteins
|-||----|----||-||||||||-|||||||||||||----|||||-|||||||||||||||||| 49 [T] COG0642 Signal transduction histidine kinase
--|||||||-||||||||||||||--||||||||||||----|||||||||||||||||||||||| 45 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
|-||---||--|----||||||----|||||||||||||---|||||-||||||||--||||||-- 40 [K] COG1309 Transcriptional regulator
|||||||||||||||||||||||||-||||||||||||----|||||||||||||||||||||||| 37 [QR] COG0500 SAM-dependent methyltransferases
---|||--|-||||-----|||----|||||---|-||----|||||-||---|||---|||||-- 34 [I] COG1960 Acyl-CoA dehydrogenases
|-||--|||----|||-|||-|--||-||-|----|||----|||||-|||||--|||||||||-- 32 [T] COG0784 FOG: CheY-like receiver
----------------||||-|--|-|||||---||||----|||||-||--|--|---|||||-- 30 [T] COG2199 FOG: GGDEF domain
|-||----|-----|-||||-|||-||||||----|||----|||||-||--|--|--||||||-- 30 [T] COG2202 FOG: PAS/PAC domain
--||||--|-|||||||-||||---|||||||-||||||||||||||-|||||||||||||||||| 29 [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) 
--|-----|-|-|----||||||||-||||||||||||----|||||-||||-||||||||||||| 28 [ET] COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain
--||--|||--------|||-|--||----|----|||----|||||-||--|--||||||-||-- 26 [NT] COG0840 Methyl-accepting chemotaxis protein
----------------||||||||--||||||||||||----|||||-|||||||||||||||||| 24 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
----------------|-|||---------------------|||||-||||||||||||||||-- 24 [P] COG1629 Outer membrane receptor proteins, mostly Fe transport
|-|||||||-|||||||||||||||-|||-||-|||||----|||||||||||||||||||||||| 21 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily
----------------||||||--|||---|-||||||----|||||-|||||||||||||||||| 21 [M] COG0845 Membrane-fusion protein
||||||---||||||-|-||||----|||||||||||||---|||||-||-|-|||||||||||-| 21 [C] COG1012 NAD-dependent aldehyde dehydrogenases
-------------||----|------||||-||||||-----|||||-||-----|--||-||--- 21 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins
----------------|-||-|---||||||----|||----|||||-||--|--|---||||||| 20 [T] COG2200 FOG: EAL domain
|||||||||-||||||||||||||--|||||||||||||---|||||-||||||||||||||||-| 19 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
||||||||||||||||||||||---|||||||||||||----|||||-|||||||||||||||||| 18 [M] COG0438 Glycosyltransferase
--|||||||-|||||-|-||-|||-|||||||||-|||----|||||-||||||||||||||||-- 18 [E] COG0665 Glycine/D-amino acid oxidases (deaminating)
----------------|-|||---------------------|||||-|||||||||||||||||| 18 [MU] COG1538 Outer membrane protein
-----------------|||||--|-||||||--||||----|||||-||||||||---|||||-- 18 [K] COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
-------------||---||------------||--------|||||-||||||||---||||||| 17 [O] COG0625 Glutathione S-transferase
---|||--|-|||||-|--|||----|||||-|||-||----|||||-||--|--|---||||||| 17 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase
|-|-------|-----||-|||--|-|||-||||||||----|||||-||||||||---||||||| 16 [K] COG1396 Predicted transcriptional regulators
------------------||-|----|||-||||||||----|||||-||||||||---|||||-- 16 [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
--|-----|---------||-|----||||------||----------||---|||||||||||-- 14 [C] COG2010 Cytochrome c, mono- and diheme variants
|-||--|||--||||---||||----||||||||||||----|||||-||||||||--||||||-- 13 [E] COG0346 Lactoylglutathione lyase and related lyases
||||||--||||||||--|||-||--|||||||||||||||||||||-|||||--|---||||||| 13 [E] COG0531 Amino acid transporters
---|----|-|-|----|||||--||----||||||--|||||||||-||||-|||---|||||-- 13 [E] COG0687 Spermidine/putrescine-binding periplasmic protein
|||||||||||||----|-|||----||||||||||||----|||||-||--||||---|||||-- 13 [K] COG1846 Transcriptional regulators
------------------------------------------|------|-----|---||--|-- 13 [PT] COG3712 Fe2+-dicitrate sensor, membrane component
|||||||||||||||-||||||--|||||-||||||-|-||||||||-||-|---|---|||||-- 12 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases
-||-----||---||--|||||||--|---|--||-||----||||--||||---|---|||||-- 12 [P] COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components
--|-------------||||||---|----|---|-||----|||||-|||||||||||||||||| 12 [V] COG0841 Cation/multidrug efflux pump
|||||||||||||--------|----|||-|-----||----|||||-||||-|||---|||||-- 12 [K] COG1522 Transcriptional regulators
||||||||||||||||--|-||---||||||||-||||----|||||-|||----|||-||||||| 11 [I] COG0183 Acetyl-CoA acetyltransferase
|-|-||--|||||----||--|----|---------||----|||||-|||||--|--||||||-- 11 [E] COG1280 Putative threonine efflux protein
--|||||||||||||-||-|-|--|||||-||||||||----|||||-||--||||--||||||-- 11 [Q] COG1335 Amidases related to nicotinamidase
||||----||-|-------|-|----||||--||||||-|--|||||--|--|--|---|||||-- 11 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
---------||-------||-|----||||||--||||----|||||-||-----|---|||||-- 11 [K] COG2771 DNA-binding HTH domain-containing proteins
||||||||||||-||-||||||---|||||||-|||||----|||||-||||||||||||||||-- 10 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases
--|-----|-|-|----|||||||--|---||||||||----|||||-|||--||||||||||||| 10 [E] COG0765 ABC-type amino acid transport system, permease component
--||||--|--|-||--|-|||----|||-|||-||||-|--|||||-||--|--|---|||||-- 10 [C] COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family
--|||||||-||--|-|----|----|||--|||||||----|||||-||||---|||||||||-- 10 [Q] COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism
----------------|---|-||||-----------|----|||||-||-||||||||||||||| 10 [T] COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
----------------|--||-||||-||-------------|||||||||||||||||||||||| 10 [M] COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins
-------------------|-----------------------||||-||-----|---|--|--- 10 [S] COG3501 Uncharacterized protein conserved in bacteria
|||-||-||||||||-||||-|----||||||-|||||----||||||||||||||--||||||--  9 [EH] COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]
---|--||--|||||-||||||----||||||||||||----||||||||||||||||||||||--  9 [J] COG0251 Putative translation initiation inhibitor, yjgF family
|-||||--|-|||||---||-|||--||||-||-||||----|||||-||||||||--||||||||  9 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II
||||||||||||||||||||||---||||||||||||||||||||||-||||||||||||||||||  9 [M] COG0463 Glycosyltransferases involved in cell wall biogenesis
|-||||--|-|||||||||||||||-||||||||||||----||||||||||||||||||||||||  9 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
|||||||||-||||||||||||||||||||||||||||||||||||||||||||||||||||||||  9 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins
--||||----||-||-|--|-|----||||-|--||||----|||||-||-||--|---|||||--  9 [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases
--|-----|-------|-||||----||||||||||||----|||||-||||||||||||||||||  9 [K] COG0789 Predicted transcriptional regulators
----||||--|||||--|-|||----|||||-||||||----|||||-||-|---|---|||||--  9 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
---|------------||---|----|||-------||----|||||-||||---|--||||||--  9 [K] COG1414 Transcriptional regulator
----------------|-----------------|-|-----|||||-|||--|||---|||||||  9 [V] COG1566 Multidrug resistance efflux pump
----------------||||||||------||||||||----|||||-|||||--|--|---||--  9 [NU] COG2165 Type II secretory pathway, pseudopilin PulG
--|-||--|----||---||||----|||--|||||-|||--|||||-|||--|||---|||||--  9 [L] COG2801 Transposase and inactivated derivatives
--------------------------|||--|--||||----|||||--||||--||||||-|---  9 [G] COG2814 Arabinose efflux permease
|||||||||||||||-||||-|----||||-|||||||----|||||-||||||||||||||||||  8 [E] COG0174 Glutamine synthetase
--||||--|-|||||-|-||||----|||||-----||----|||||-||||||||||||||||--  8 [C] COG0277 FAD/FMN-containing dehydrogenases
|-|||||||-|||||-||||-|--|-|||||--|||||----|||||-||--||||||||||||--  8 [R] COG0388 Predicted amidohydrolase
||||||||||||||||||||||----||||||||||||----||||||||||||||||||||||--  8 [R] COG0491 Zn-dependent hydrolases, including glyoxylases
|------------||||||||||||||||||||||||||-|||||||-||||||||||||||||||  8 [O] COG0542 ATPases with chaperone activity, ATP-binding subunit
|||||||||||||-|-|-||-|----||||-|||||||----|||||-||||-|||---|||||||  8 [T] COG0589 Universal stress protein UspA and related nucleotide-binding proteins
-||-----||-------|||||||--|---|--||-||----||||---|||---|---|||||--  8 [P] COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component
|||||||||||||---||||||----|--|||--||||----|||||-||||||||||||||||--  8 [R] COG0730 Predicted permeases
----------------||||||--||||||||--||||----||||||||||||||||||||||||  8 [M] COG0739 Membrane proteins related to metalloendopeptidases
-|||||-|-----||--|-|||----||||||||||||--|-|||||-||-|-|||||||||||||  8 [J] COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
----|------|-----|--||----|||-|||-||||----|||||-||---|||---|||||--  8 [K] COG1802 Transcriptional regulators
-------------||||||||||||||||||||||||||||||||||-||||||||||||||||||  7 [I] COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase
|||||||||||||||-||||||--||||||||||---|-|--||||||||||||||||||||||||  7 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs
---|||----||-||||-||-|||--||||||||||||||||-|-|--|||||--||--|--|---  7 [RTKL] COG0515 Serine/threonine protein kinase
|||||||||||||||-||||||||-|||||||||||||----|||||-||||||||||||||||||  7 [R] COG0517 FOG: CBS domain
|||||||||||-|||-----|--|--||||||----------|||||-||||||||||||||||--  7 [E] COG0560 Phosphoserine phosphatase
-------------||---||-|----|||-----|-||----|||||-||-|||||---|||||||  7 [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
-------------|||||||||--||----||||||||----||||||||||||||||||||||||  7 [O] COG0760 Parvulin-like peptidyl-prolyl isomerase
-------------|||-----|--------------------|||||-||||-|||||||||||--  7 [R] COG0790 FOG: TPR repeat, SEL1 subfamily
|-||||----|||---|-||||--|-|||-|---||||----|||||-||||||||||||||||--  7 [R] COG0824 Predicted thioesterase
---|---------||-----||----|||-----|-||----||||||||--||||---|||||--  7 [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1
-||-||--||||-----|||||||--|---|--||-||----||||---||||--|---|||||--  7 [P] COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component
------------------|--|------------|||-----|||||-||||||||--|||||---  7 [S] COG1289 Predicted membrane protein
----||--|-|--|||-||||-||--|---||||||||||--||||||||||||||||-|||||||  7 [I] COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes
--|---||--|-|-----||-|----||||||||||||----|||||--|--|--|---|||||||  7 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins
-------------------|-|----|||-||||||||||--|||||-||-----|---|||||--  7 [K] COG2188 Transcriptional regulators
-------------||---||----------------------|||||-||||----------|---  7 [T] COG2198 FOG: HPt domain
------------------|--|--------------------|||||--|--|--|---||-|--|  7 [NU] COG3121 P pilus assembly protein, chaperone PapD
--------------------------|-------|--|----------||---|||---|---|--  7 [S] COG3182 Uncharacterized iron-regulated membrane protein
--||----|-|-|----|||||--|||---||||||-||||||||||-||||-|||--||||||--  7 [E] COG3842 ABC-type spermidine/putrescine transport systems, ATPase components
-------------------------------------------||----|-----|---|||||--  7 [K] COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain
-|-----------||-|---||-|--|||||---|-||----||||||||||||||||||||||--  6 [H] COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
|-||||--|-|||||||-||-|-----||--|--||||----|||||-||-||--||-||||||--  6 [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases
--||---------||---||||----|||-|----|||----|||-|-||-|---|---|||||--  6 [R] COG0384 Predicted epimerase, PhzC/PhzF homolog
|||||||||||||||-||||-|----|---|--|---|----|||||--||||--|||||||||--  6 [FR] COG0402 Cytosine deaminase and related metal-dependent hydrolases
|||||||||||||||-|||||||||-||||||||||||----|||||-||||||||||||||||||  6 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase
|||||||||--|-|||||||||||||----||||||||----|||||-||-|||||||||||||||  6 [R] COG0457 FOG: TPR repeat
|||-||--|--|-||||-||||--|-||||||||||||||||||||||||||||||||-|||||||  6 [LKJ] COG0513 Superfamily II DNA and RNA helicases
|-||||--|-||-||||-||||---|||||||||||||----|||||||||||||||||||-||||  6 [P] COG0607 Rhodanese-related sulfurtransferase
---|||----|||||-||||||---|||||-|--||||----|||||-||--|--||--||-||--  6 [C] COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)
|||||||||||||-||||||||--|||||-||||||||----||||||||--||||||||||||||  6 [M] COG0668 Small-conductance mechanosensitive channel
--||--|||--------|||----||----|----|||----|||||-||--|--||||||-||--  6 [NT] COG0835 Chemotaxis signal transduction protein
--|||||||--||||--|-|-|-----||-||||||||--|-|||||-|||-||||---||-||--  6 [ER] COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
--------------------------|||||||-||||----|||||--|---------|-|----  6 [E] COG1113 Gamma-aminobutyrate permease and related permeases
--||--||--||-|||||||||||--||||||||||||||||||||||||||||||||||||||||  6 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components
---|----|-|-|----|-|||--||----||||||--|||||||||-||||-|||--||||||--  6 [E] COG1177 ABC-type spermidine/putrescine transport system, permease component II
---|||--|-|||-------||-----||||---|-||----|||||-||-----|---|||||||  6 [I] COG1250 3-hydroxyacyl-CoA dehydrogenase
---|------------||--||----|||||||-||||----||||||||||||||---|||||||  6 [K] COG1278 Cold shock proteins
--||--------------|-||----|||-||-|-||-----|||||-||-|-|||---||-||--  6 [S] COG1359 Uncharacterized conserved protein
--||---------------|-|-----|||||---|||----|||||-||---||---||||||--  6 [P] COG2076 Membrane transporters of cations and cationic drugs
|-|-||----|||---|-||-|-----||-||---|||----|||||-||||-|||-|-|||||--  6 [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
--|----------------------|-----||--||-----|||||--|-----|---||||---  6 [E] COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components
-------------||------------|||------------||||--||-----|------|---  6 [Q] COG2175 Probable taurine catabolism dioxygenase
||-|-----|---------|-|-----|||----|-------||||---|-----|--||||||--  6 [E] COG2303 Choline dehydrogenase and related flavoproteins
------------------|||----------------------|||---|||||||--|----|--  6 [U] COG3210 Large exoproteins involved in heme utilization or adhesion
--|--------|-------||-----||||--||---|-------|---|---||----||-||--  6 [L] COG3547 Transposase and inactivated derivatives
-----------------|||------|||-------------||||---|-----|---|||||--  6 [PR] COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit
--||||-|--|||||-||||||----||||||||||||----||||||||||||||||||||||--  5 [E] COG0031 Cysteine synthase
||||||-||||||||-||||||----||||||||||||----||||||||||||||||||||||--  5 [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I
||||----|||||||-||||||||||||||||||||||||||---|---|---|||||||||||||  5 [J] COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases
|||||||||||||||---||-|----||||----||||----|||||-||-|-|||--||||||--  5 [Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
||-||||||||||---|-||-|----|||-------||----|||||-||||---|||||||||--  5 [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing
-------------||-||||||||--||||||||||||----||||||||||||||||||||||||  5 [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase
----------------|-||||||---||-||||||||----|||||-||||||||||||||||||  5 [I] COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III
-------------|||--||||||||||||||||||||-|--||||||||||||||||||||||||  5 [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains
|||||||||||||||||-||||----|||||-||-|||----||||||||||||||||||||||--  5 [O] COG0501 Zn-dependent protease with chaperone function
---|||----|||||---||-|||--||||-|||||||-|||||||||||||||||---|||||||  5 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes
|||||||||-|||||||-||||||-|||||||||||||||||||||||||||||||||||||||||  5 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
|-||--|||----|--|-||-|--|||||-|||||||||---|||||-||||||||||||||||--  5 [R] COG0546 Predicted phosphatases
|-|||||||--||||---|-|--|--|------||-||----|||||-||||-||||||||||-||  5 [ER] COG0591 Na+/proline symporter
-|--|||||||||||-||--||-|--||||||||||||----||||||||||||||||||||||||  5 [E] COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases
-------------||||||||||||-|||||||-||||----|||||-||||||||--||||||--  5 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
-||||||||||||||-|-||||--||-||-|--|||||-||||||||-||-||--|--||||||--  5 [R] COG0693 Putative intracellular protease/amidase
|||||||||||||---||||-|---||||||---||||----|||||-||--|--|---|||||--  5 [R] COG0714 MoxR-like ATPases
--|||||||-|||---||||||||--|||||||-||||----|||||-||||---||||||||---  5 [E] COG0747 ABC-type dipeptide transport system, periplasmic component
----||----------||||||||||-|||||||||||||||||||||||||||||||||||||||  5 [L] COG0776 Bacterial nucleoid DNA-binding protein
------------------||-|||--||||||---|||----|||||-||||||||||||||||--  5 [M] COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
|-|------|------|-||||||------------------|||||-||||||||||||||||||  5 [U] COG0811 Biopolymer transport proteins
|-||||||||||||||-|||-|----||||||||||||----|||||-||-||--|||-|||||--  5 [V] COG0842 ABC-type multidrug transport system, permease component
------------------||-|----|||-|---||||----||||||||||||||||||||||||  5 [P] COG0861 Membrane protein TerC, possibly involved in tellurium resistance
|||---|||||||---|-||-|----||||||-|-|||-------|--||-----|---|||||-|  5 [F] COG1051 ADP-ribose pyrophosphatase
--||---||---||||-|-|||||--|||-|||--|||----|||||-||-||--|---|||||--  5 [R] COG1073 Hydrolases of the alpha/beta superfamily
|-||||||||||||||-|||-|---||||||||||||||||-|||||-||-|||||||-|||||--  5 [V] COG1131 ABC-type multidrug transport system, ATPase component
||||----|||||---|||||||||||||-||||||||||||||||||||||||||||||||||||  5 [V] COG1136 ABC-type antimicrobial peptide transport system, ATPase component
---|----|-|-|----|-|||--||----||||||--|||||||||-||||-|||---|||||--  5 [E] COG1176 ABC-type spermidine/putrescine transport system, permease component I
||||||--|||||||-||||||||--||||-|||||||-|||||||||||||||||---|||||||  5 [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
|-|---||||||----||||-|-----||||----|||-----------||||--|---||-||--  5 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases
----------------|---|-||------------------|||||-||--|--|--|---||--  5 [NU] COG1450 Type II secretory pathway, component PulD
----------|||---|----|--|--||-------||----|||----|-----|---||-||--  5 [C] COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs
---|||----|||--------|||--|-------||||----||||||||||-|||||||||||--  5 [I] COG1607 Acyl-CoA hydrolase
----------------|-----||||----|-----||----||||||||||||||--||||||||  5 [T] COG1734 DnaK suppressor protein
-----|--|-||---------|-----||-------------|||-|--|-----|---|||||--  5 [C] COG1804 Predicted acyl-CoA transferases/carnitine dehydratase
----------|||--------|--||-||-------||----|||----|-----|---||-||--  5 [C] COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs
|-||----|-----|-||||-|-----||||---|-||----|||---||-----|---|||||--  5 [T] COG2203 FOG: GAF domain
-------|------|--|--||----|---||||||||----|||||-||||-|||---|||----  5 [F] COG2233 Xanthine/uracil permeases
--|-----------|-----|---------|----||||---|||||-||||-||||||-|-||--  5 [R] COG2249 Putative NADPH-quinone reductase (modulator of drug activity B)
----------------||||||||------||||||||----|||||-||||||||--|---||--  5 [NU] COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB
------------------|||----------------------|||---|||||||--|----|--  5 [U] COG2831 Hemolysin activation/secretion protein
------------------------------------------|||||-||-----|---|--|---  5 [S] COG3157 Hemolysin-coregulated protein (uncharacterized)
-----------------|-|--------------------------|--|---------||-|---  5 [R] COG3450 Predicted enzyme of the cupin superfamily
------------------------------------------|||||--|--|-------------  5 [NU] COG3539 P pilus assembly protein, pilin FimA
||||||||||||-||-||||||----||||||||||||----||||||||||||||||||||||--  4 [F] COG0015 Adenylosuccinate lyase
||||||-|||---|||--||-|----|||--|-||||-----|||||-||-||------|--|---  4 [P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters
|||||||||||||||-||||||----||||||--||||----||||||||||||||--||||||--  4 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase
-|||--|||-|||-----||-|---------------|--||||||||||||||||---|||||--  4 [HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)
||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||--  4 [P] COG0226 ABC-type phosphate transport system, periplasmic component
|||-|||||||||---||||-|-----||-|------|----||||||||||||||---|||||--  4 [R] COG0312 Predicted Zn-dependent proteases and their inactivated homologs
|||||||||||||---|||||-||--||||||||||||----||||||||||||||||||||||||  4 [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase
|||||||||||-||||----------||||||---|||----|||||-||--|-------|-|---  4 [E] COG0367 Asparagine synthase (glutamine-hydrolyzing)
---|---------||---||-|----|||--|||||||--|||||||-||-|-|||---||-||--  4 [R] COG0431 Predicted flavoprotein
|||-----|--|-||-|-||-||||--||-||||||||----|||||-||||||||||||||||--  4 [I] COG0439 Biotin carboxylase
|||-|||||-|||||||||||||||--|||-||-||||----||||||||-||--|||||||||||  4 [O] COG0450 Peroxiredoxin
||||||||||||||||||||||----|||||||||||||---|||||-||||||||--||||||--  4 [R] COG0456 Acetyltransferases
|||---|||--|-||-|||||||||-||||||||||||----|||||-||||||||||||||||--  4 [I] COG0511 Biotin carboxyl carrier protein
||||||-||||||||-||||||----||||||||||||----||||||||||||||||||||||--  4 [EH] COG0512 Anthranilate/para-aminobenzoate synthases component II
|||||||||||||||-||||||-|-|||||||||||||----|||||-||||||||||||||||--  4 [F] COG0518 GMP synthase - Glutamine amidotransferase domain
|-||--||-|-||-|--||||||||||||||||||||||||||||||-|||||--|||||||||--  4 [E] COG0520 Selenocysteine lyase
--|----------||-|-||||----|||-----|-||----|||||-||--||||||-|||||--  4 [R] COG0523 Putative GTPases (G3E family)
|||-||||||-|-||-||--|---|-|||-||-|-|||----|||||-||---|||---|----||  4 [HC] COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases
-------------||---||-||||-|---------------||||||||||||||-------|--  4 [O] COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1
-------------|||||||||||||||||||||||||||||||||||||||||||||||||||||  4 [J] COG0564 Pseudouridylate synthases, 23S RNA-specific
||||----||||-----||||||||-|||-||||||||----|||||-||-|-|||--||||||--  4 [V] COG0577 ABC-type antimicrobial peptide transport system, permease component
----|--||---|----||||-----|||-|---|--|-||||||-|-||--||||||||||||--  4 [R] COG0579 Predicted dehydrogenase
---|||-|--|-||||-|-|||--|-||||||||||||-||||||||-||||---|---|||||--  4 [C] COG0584 Glycerophosphoryl diester phosphodiesterase
----||-----|------||-|--||||||||--||||----|||||||||||||||||--|||--  4 [S] COG0586 Uncharacterized membrane-associated protein
--|-|||---||-||--|||-|||--|||||||-||||-|--|||||-||||||||---|||||--  4 [R] COG0637 Predicted phosphatase/phosphohexomutase
|||||||||||||---||||||----|||||||-||||----|||||-||-|||||--||||||--  4 [K] COG0640 Predicted transcriptional regulators
--||--|||--------|||-|--||----|----|||----|||||-||--|--||||||-||--  4 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases
--|----------||||-||--||--||||-|---|||----|||-|-||-|---|||-||-|---  4 [P] COG0659 Sulfate permease and related transporters (MFS superfamily)
|||---||||------|||||------||-------||----|||||-||--||||||-|||||--  4 [G] COG0662 Mannose-6-phosphate isomerase
||||--||-|-|-||||-||||--|-||||||||||||----|||||-|||||--|||-|||||||  4 [I] COG0671 Membrane-associated phospholipid phosphatase
-|-|----|-|||----|||||----|------|---|----|||||--|-----|--|||||---  4 [E] COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
|||||--||||||---||||||----||||||||||||----|||||-||||||||||||||||--  4 [C] COG0778 Nitroreductase
----------------|-||||||------------------|||||-||||||||||||||||||  4 [U] COG0848 Biopolymer transport protein
----||||--|||||-|-|||---|-----|-|-||||----|||||-||||-|||||||||||--  4 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases
--|-----|-|-|----|||||||--|---||||||||----|||||-|||--|||||||||||||  4 [E] COG1126 ABC-type polar amino acid transport system, ATPase component
||||||-|||||-----|||-|----|||||-----------|||-|-||--|--|||||||||||  4 [C] COG1146 Ferredoxin
---|||----|||||--|||||----||||-|-|||||----|||||-||||||||--||||||||  4 [E] COG1171 Threonine dehydratase
----------------||||||||||||||||||||||-|--||||||||||||||||||||||||  4 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases
||||||||||-|||--||||-|----|||-||---|||||--|||||-|||-||||||||||||||  4 [P] COG1226 Kef-type K+ transport systems, predicted NAD-binding component
--||--|||--------|-|----||----|----|||----|||||-||-----|--|||-||--  4 [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins
----||||---|-|---------------------|||----|||-|--|-|-||-----------  4 [F] COG1457 Purine-cytosine permease and related proteins
----------------||||||||------||||||||----|||||-||||||||------||--  4 [NU] COG1459 Type II secretory pathway, component PulF
-----------------|--||----|||-||||||||-|--|||||-|||||--|---|||||--  4 [K] COG1609 Transcriptional regulators
-----------------||-|---|-|---------||----|--||-||||---|---||-||--  4 [G] COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
-----------------|------|-----------------------||--------|-------  4 [T] COG1639 Predicted signal transduction protein
||||||--|--||-----||||----|||-||--||||----|||||-||-||--|--|||-||--  4 [K] COG1733 Predicted transcriptional regulators
--|-||----|-------||------|||-|-----------|||||-||-|---|---|||||--  4 [R] COG1741 Pirin-related protein
--|----------------|||----||||-||||||------||-|--||-||||---|||||-|  4 [I] COG1835 Predicted acyltransferases
--||------|-|-----|||-----|-----|||--|-----||||-||||||||--|||||---  4 [P] COG1840 ABC-type Fe3+ transport system, periplasmic component
---|----|--|-||-----||----||||----|-|-----|--||-||-----|---|||||--  4 [I] COG2030 Acyl dehydratase
-------------||---|--|----||||------||-----------|-----|---||-||--  4 [P] COG2072 Predicted flavoprotein involved in K+ transport
---------------------|----|||||----|||----|||||-||||-|||---|||||--  4 [K] COG2186 Transcriptional regulators
--||--|||--------|-|----||----|-----||----|||||-||--|--|--|||-||--  4 [NT] COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain
|-||||-||-|||||-|||||||||-|||||||||||||---|||||-||||-|||||||||||--  4 [P] COG2217 Cation transport ATPase
---------------------|----|||-|---||||----|||-|--||----|--||-|----  4 [S] COG2258 Uncharacterized protein conserved in bacteria
---|-------|-||----|-|----||||----|-||----|||||-||||-|||---|||||--  4 [S] COG2259 Predicted membrane protein
----||--|-|||-----||-|---------------------------|-----|-----|-|--  4 [R] COG2366 Protein related to penicillin acylase
----------|-|------||-----||-|-||||||-----|||||-||||-|||---|||||--  4 [S] COG2606 Uncharacterized conserved protein
---------------------------||-|-----------|||||-||----------------  4 [K] COG2909 ATP-dependent transcriptional regulator
--------------------------|||-------------|||||-||-|||||---|||||--  4 [M] COG2951 Membrane-bound lytic murein transglycosylase B
------------------|-----------------------|||||-||-||-||---|||||-|  4 [C] COG3038 Cytochrome B561
------------------|-----------------------|||||--|--|--|---|--|--|  4 [NU] COG3188 P pilus assembly protein, porin PapC
-------------------|-------||||-----||-------|---|-----|---|--|---  4 [Q] COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis
------------------------------------------------||---|||||||||||--  4 [O] COG3278 Cbb3-type cytochrome oxidase, subunit 1
--------------|-------------------------------|--|-----|---|||||--  4 [S] COG3791 Uncharacterized conserved protein
---------|--------------------------------------||----------------  4 [O] COG4067 Uncharacterized protein conserved in archaea
---------------------------------------------|---|-----|---|--|--|  4 [S] COG5430 Uncharacterized secreted protein
||||||--|||||-|-|-||||||--|||||---||||----|||||-||-|||||||||||||--  3 [H] COG0001 Glutamate-1-semialdehyde aminotransferase
||||||--|||||||-|-||||----|||||---||||----||||||||--||||---|||||--  3 [H] COG0007 Uroporphyrinogen-III methylase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  3 [J] COG0008 Glutamyl- and glutaminyl-tRNA synthetases
|||||||||||||||---||||--------|-|-|-||----|||-|-||-|||||||-||||---  3 [E] COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family
---|||----||||||--||-|||---||--|||||||-|||-------|-----|---|||||||  3 [C] COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  3 [D] COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control
||||----||---|||||||||||||||||||||||||----|||||-||||||||||||||||||  3 [J] COG0042 tRNA-dihydrouridine synthase
|||||||||||||||-||||||----||||||||||||----|||-|--|--|--|||||||||--  3 [F] COG0044 Dihydroorotase and related cyclic amidohydrolases
||||||||||||||||||||||||||||||||||||||-|||||||||||||||||||||||||--  3 [G] COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  3 [R] COG0073 EMAP domain
|||---||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||||  3 [L] COG0084 Mg-dependent DNase
||||---|-||--||--|||-|||--||||||||||||----|||-|-||-|-|||--||||||-|  3 [R] COG0110 Acetyltransferase (isoleucine patch superfamily)
|||||||||||||||-||||-|----||||||--||||----|||||-|||||--|||||||||--  3 [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases
||||||||||||||||||||-|||||||||||||||||-|||||||||||||||||||||||||||  3 [E] COG0112 Glycine/serine hydroxymethyltransferase
|||--|||||||-||-||||-|----|||||--|||||----||||||||||||||--||||||--  3 [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases
||||--|||||||||||-||-|------------|-||----------||---|||---|||||--  3 [BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein
--------|-||-||-|-||-|----|||-|-----||----||||||||--||||---|||||--  3 [P] COG0155 Sulfite reductase, beta subunit (hemoprotein)
|-|||||||-|||||||||-|||||-||||||||||||-|||||||||||||||||||||||||||  3 [F] COG0209 Ribonucleotide reductase, alpha subunit
|-||||-------||-||||||||||||||||||||||||||||||||||||||||||||||||||  3 [L] COG0210 Superfamily I DNA and RNA helicases
||||-||||||-|||-||-||------||||-||-|||-||-|||||-|||||--|||--||||||  3 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
--|----------||-||||||||||||||||||||||||||||||||||||||||||||||||||  3 [IQ] COG0236 Acyl carrier protein
||||||--|||||---|-||||----||||-|----||----|||||-||||-||||||||||---  3 [C] COG0247 Fe-S oxidoreductase
-------------||---||-|-----|||------------|||||-|||-||||---|||||--  3 [H] COG0259 Pyridoxamine-phosphate oxidase
|--|------||-||---||-|----|||||-||--||----|||||-||||||||||||||||--  3 [P] COG0288 Carbonic anhydrase
||||||||||||-|---|-|-|||--|||||---||||----||||||||||-||||||||-|---  3 [P] COG0306 Phosphate/sulphate permeases
--|----------||-|-||-|----||||----|-||----||||||||||||||---|||||||  3 [S] COG0316 Uncharacterized conserved protein
----------------||||||---||||||||||||||-|||||||-||||||||||||||||-|  3 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases
-||-||--||-|------||----------|-----------|||-|-||||-|||||||||||--  3 [C] COG0348 Polyferredoxin
||||||||||||||--||-||-|||-||||||-|||||-|--|||||-||||||||||||||||-|  3 [L] COG0350 Methylated DNA-protein cysteine methyltransferase
--|----------|--|-||------|--|----|-||----|||||--|---|||---|||||--  3 [R] COG0385 Predicted Na+-dependent transporter
-------------|||--|-|-----|---|||||||||---|||||--|--||||-------|--  3 [O] COG0386 Glutathione peroxidase
||||--||||------||||------|||||---|||-|||||||-|--|--|--|---||||---  3 [S] COG0392 Predicted integral membrane protein
---|||||---||||-||||-|-----|||----||||----|||||--|--||||---|||||--  3 [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase)
----||----||||||--||||----|||-----|-||----|||-|-||--||||||-||-||--  3 [E] COG0405 Gamma-glutamyltransferase
-|------|-|||----|||||----|------|---|----|||||--|-----|--|||||---  3 [E] COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
--|-|------|-||-|-||-------|||------|-----|||||--|-----|---||-||--  3 [Q] COG0412 Dienelactone hydrolase and related enzymes
-|--|||||||||||-||---|----|---|--|--||----||||||-|--||||||----|---  3 [E] COG0421 Spermidine synthase
||||||--||||----|||||-------------|-|-----||||||||||-|||--||||||--  3 [O] COG0425 Predicted redox protein, regulator of disulfide bond formation
|-||||-------|||||||||||||||||||||||||||||||||||||||||||||||||||||  3 [O] COG0443 Molecular chaperone
||||||||||||||-|||||||||||||||||||||||||||||||||||||||||||||||||||  3 [O] COG0492 Thioredoxin reductase
---|||||---||||-||||-|||---|||--|-||||-|--|||||-||--||||---|||||--  3 [E] COG0509 Glycine cleavage system H protein (lipoate-binding)
|||||||||||||||--|||-|----||||||||||||----|||||-|||||--|---|||||--  3 [G] COG0524 Sugar kinases, ribokinase family
||||--|||---|||-|||-||--|||||-|||||||||||||||||-||||||||||||||||--  3 [V] COG0534 Na+-driven multidrug efflux pump
---|||-||--|||--||||||---|||||||||||||-||||||||-|||||--|---|||||--  3 [C] COG0554 Glycerol kinase
-|------|-|||----|||||----|------|---|----|||||--|-----|--|||||---  3 [E] COG0559 Branched-chain amino acid ABC-type transport system, permease components
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  3 [K] COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)
---|||-----|-|||--|--|---|||||-|||||||----|||||-|||||--|---||||---  3 [C] COG0578 Glycerol-3-phosphate dehydrogenase
-||---|-|-||-||-||||||----|||||||||||-----|||||-|||||--|||||||||-|  3 [P] COG0598 Mg2+ and Co2+ transporters
|||-||--||-|-||--||--|----|||--|---|||-------|---||-||||---|||||--  3 [S] COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit
-||||||||-|||----|||||----|---|||||||||---|||||-||||---|||||||||--  3 [P] COG0609 ABC-type Fe3+-siderophore transport system, permease component
----------|-|||-||||||---|-|||||||||||----|||||-|||||--|||||||||||  3 [R] COG0612 Predicted Zn-dependent peptidases
||||--|||-------||||||--|||||-||||||||----||||||||||||||||||||||||  3 [R] COG0628 Predicted permease
-----|-------||-|-||-|||--||||||||||||||||-------|--|--||--|--|---  3 [T] COG0631 Serine/threonine protein phosphatase
|||-||||-|-|----|-||-|----|||-|-----||----|||-|-||--||||--||||||||  3 [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily
----||----|--|||--||||--|||---|-----------||||--||-|||||--|||-||||  3 [R] COG0666 FOG: Ankyrin repeat
|-||||||-|||-||-||||-|----|---||||||||----|||||-||-|---|||||||||--  3 [R] COG0673 Predicted dehydrogenases and related proteins
||-------|---||-|||||-----|---||--||||----||||--||-||--|--||||||||  3 [R] COG0679 Predicted permeases
|-|-||--|--|-|||--||||--|||||-||||-||-----|||||-||||||||||||||||||  3 [L] COG0708 Exonuclease III
-|||--|||-||------||-|---------||---------|||||-||--|--||||-|-|---  3 [R] COG0727 Predicted Fe-S-cluster oxidoreductase
--|-||--|-|||---||||||---||||||||-||||--|||||||-||||||||||||||||--  3 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins
----------------||||||||||||||||||||||----||||||||||||||||||||||||  3 [OU] COG0740 Protease subunit of ATP-dependent Clp proteases
-----------------|||||----||||||||||||----||||||||||||||||||||||--  3 [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein)
-------------||------|----|-------||||----|||||-||||-||||||||||---  3 [P] COG0753 Catalase
----------------||||||||||||||||||||||----||||||||||||||||||||||||  3 [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2
-----------------|---|||||||||||||||||||||||||||||||||||||||||||||  3 [K] COG0782 Transcription elongation factor
----------------|--||---------------------|||||-||||||||||||||||--  3 [M] COG0810 Periplasmic protein TonB, links inner and outer membranes
-------------|||------||--|---------------|||||-||||-||-|||-------  3 [E] COG0814 Amino acid permeases
|||------|-|----|--|||--------||||||||----|||||-||||-|||||||||----  3 [O] COG0826 Collagenase and related proteases
--||--|||-------||||-|--------|-----------|||||-||--|---||-|||||-|  3 [M] COG0836 Mannose-1-phosphate guanylyltransferase
----|---|----||||||--||||-|||-||||||||----||||||||||||||||||||||||  3 [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
-|||---||--|----|-||------|||---|---||----|||||-||-||--|--||||||||  3 [M] COG1004 Predicted UDP-glucose 6-dehydrogenase
||||--||-|||-|||-|-|-|--|||||-||||||||----|||||-||-|-|||---|||||--  3 [R] COG1011 Predicted hydrolase (HAD superfamily)
||-|||--|||||||-||||||||--||||||--||||----|||||-||||||||||||||||||  3 [C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit
---|||----||||||--||-|||---||--|||||||-|||-------|-----|---|||||||  3 [C] COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
-|----||-|--|---||--||||-------||||||-----||||||||||||||---||||---  3 [R] COG1092 Predicted SAM-dependent methyltransferases
--|---||------------|||||-|-----|||-||----|||-|-||||-||-|||-||----  3 [E] COG1115 Na+/alanine symporter
|||-|||||||||----|||||--------|-----|-----|||||-|||||||||||||-|---  3 [C] COG1145 Ferredoxin
--|-------------||||||||||||||||||||||----|||||-||||||||||||||||||  3 [M] COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes
-------------------|----------||--||||-||||||||--||----|---||-|---  3 [I] COG1182 Acyl carrier protein phosphodiesterase
||-|-|||-|||----|-||-||||||||||----|||--|||||||-||--||||||||||||||  3 [D] COG1192 ATPases involved in chromosome partitioning
-----------------|||----------|----||-----|||||-||-----|----------  3 [KT] COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
||||||||||----|-|-|||-||||----||||||||----||||---|-----|---|||||||  3 [R] COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
--|||||||--||----|||-|--||----|---|||||||--------|-----|----||----  3 [R] COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
----------------|-||||--|--||-||-|-|||----|||||--|||---|---|||----  3 [S] COG1285 Uncharacterized membrane protein
---|--------------------|-|||-----||||----|||||-||||-||-----|-----  3 [M] COG1292 Choline-glycine betaine transporter
--||--||----|---|--||||||||||-|---|-||----|||||-||--|--|--|||-||||  3 [C] COG1301 Na+/H+-dicarboxylate symporters
----------------||--||----|---||||||||----|||||-||||-|||---||||---  3 [KG] COG1349 Transcriptional regulators of sugar metabolism
--||--------------||-|--|-|||-||---|||----|||||--|-|-------||-||||  3 [S] COG1357 Uncharacterized low-complexity proteins
----------------||------||----|----|||----|||||-||-----|||||||||--  3 [N] COG1360 Flagellar motor protein
-----------------||||||||--||-|---||||----------||---------||--|--  3 [T] COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
|-|||||||--||||-||--|-----|---||-|||||----|||||-||-|---|---||||---  3 [C] COG1454 Alcohol dehydrogenase, class IV
--------------------||-||-|---||||||||----|||||-||||||||||||||||--  3 [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen
-------------||------|-----||-------------|||||-||--||||---|||||||  3 [R] COG1485 Predicted ATPase
-----------------|||----|------|----||----|||----|-|---|-----|||--  3 [R] COG1512 Beta-propeller domains of methanol dehydrogenase type
------||------------||----|--|----|-||----|||||-|||--|||--||------  3 [R] COG1540 Uncharacterized proteins, homologs of lactam utilization protein B
-----------------|--|---|-|----------|----|--||-||||-------||--|--  3 [G] COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
||||||--|||||||-||--||----||||||||||||----||||||||||||||||||||||--  3 [E] COG1605 Chorismate mutase
--|-||||||||-|--||-|||||--||||-|--|-||----|||||-||-|||||--||||||--  3 [R] COG1611 Predicted Rossmann fold nucleotide-binding protein
---|----|-|-----|-||-|||--||||----|||-----|||||-||||||||||||||||||  3 [O] COG1651 Protein-disulfide isomerase
--|||||||-|-|---||||-|---|-|||-----|||----------||-----|---|||||--  3 [R] COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
-----------------|--------|---||||||||-|--|||||-||||-|||---|||||--  3 [K] COG1737 Transcriptional regulators
-------------||||||-|---|--|||-|----||----|||-|-||--||||---|||||||  3 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily
---|------||||--|-||-|----||||----||||----||||||-|--|--|---|||||||  3 [C] COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3
--------------------|||||||---||||||||||||||||||||||||||---|||||--  3 [G] COG1925 Phosphotransferase system, HPr-related proteins
----------------||||||-----||-||-|||||----|||||-||||||||--||||||||  3 [K] COG1959 Predicted transcriptional regulator
------||-----|------||----||||----|-||----|||||-|||--|||--||---|--  3 [E] COG1984 Allophanate hydrolase subunit 2
------||-----|------||----||||----|-||----|||-|-|||--|||--||---|--  3 [E] COG2049 Allophanate hydrolase subunit 1
----------------|---|---------------------|||||-|||||||-||-|||||--  3 [I] COG2067 Long-chain fatty acid transport protein
--------|----|--||-|||----|||-||||||||-----------|--||||||||||-|--  3 [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase
-||-|||||||||---|--|-||||-----------|-----||||||||-|||||--||||||--  3 [U] COG2095 Multiple antibiotic transporter
---|---------||---||-|----|||||-----||-----------|--|--|--||||||--  3 [Q] COG2124 Cytochrome P450
------------------||-------|||------------|||||-||--||||---|||||--  3 [P] COG2193 Bacterioferritin (cytochrome b1)
------------------------------------------|||||-|||||||-||||||--||  3 [R] COG2194 Predicted membrane-associated, metal-dependent hydrolase
-----------------||||-|||--||-|---||||----------||----------|-|---  3 [TK] COG2208 Serine phosphatase RsbU, regulator of sigma subunit
----------------|---------||||----|-||----|||-|--|-----|----||-|--  3 [P] COG2223 Nitrate/nitrite transporter
-------||----||--|-|||----||||||--||||----|||||-||||---|---|||||--  3 [I] COG2267 Lysophospholipase
----------------------||-------||-|-|-----|||||-||||------|-----||  3 [G] COG2271 Sugar phosphate permease
--|---------------||-|----|||-------------------||-----|--||||||--  3 [S] COG2326 Uncharacterized conserved protein
----||----|||------|------|||------|||----|||-|-||--||||----|-||--  3 [G] COG2513 PEP phosphonomutase and related enzymes
--|-----------------|-----|---|-|-|-||----|||||-||||-|||----------  3 [GE] COG2610 H+/gluconate symporter and related permeases
-----------|-||---||-------|||||||-|||----|||||-||-|-|||--||||||--  3 [E] COG2755 Lysophospholipase L1 and related esterases
---------------------|----|---|--|-||-----|||-|--|-----|--|--|----  3 [P] COG2807 Cyanate permease
---------------------|-----------------------|--||-|-||||||-|-----  3 [C] COG2863 Cytochrome c553
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  3 [J] COG2890 Methylase of polypeptide chain release factors
-----|--------------||----|||--|||||-|----|||||-|||----|---|||||--  3 [L] COG2963 Transposase and inactivated derivatives
--------------------|---------------------|||||-||||||||---|||||-|  3 [V] COG3023 Negative regulator of beta-lactamase expression
--------------------|-----|----------|----|--||-||||-------||--|--  3 [G] COG3090 TRAP-type C4-dicarboxylate transport system, small permease component
--||---|------|------------||-------------|||||--|||-------|||||--  3 [P] COG3119 Arylsulfatase A and related enzymes
----------||------|----------------|------|---|--|-----|---|-|||--  3 [R] COG3193 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol
--------------------------||||-------------------|------||||||||--  3 [E] COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase
------------------|-----------------------|||-|--|----------------  3 [S] COG3204 Uncharacterized protein conserved in bacteria
--|---------------------------|----||-----|||||--|-----|------|---  3 [M] COG3209 Rhs family protein
---|------|--------||-----|||--|--|--|----||||--||---------||-||--  3 [P] COG3221 ABC-type phosphate/phosphonate transport system, periplasmic component
------------------------------------------------||---|||-------|--  3 [C] COG3245 Cytochrome c5
-------------------------------------------||||-||-----|---|--|---  3 [S] COG3455 Uncharacterized protein conserved in bacteria
--------------------------|------------------|---|-----|---|||||||  3 [Q] COG3485 Protocatechuate 3,4-dioxygenase beta subunit
-------------------------------------------||||-||-----|---|--|---  3 [S] COG3515 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  3 [S] COG3516 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  3 [S] COG3517 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  3 [S] COG3518 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  3 [S] COG3519 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  3 [S] COG3520 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  3 [S] COG3522 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  3 [S] COG3523 Uncharacterized protein conserved in bacteria
---|------|--------||-----|----|--|--|-|||||||---|---------||-||--  3 [P] COG3639 ABC-type phosphate/phosphonate transport system, permease component
------------------|------------------------------|-----|-------|--  3 [M] COG3659 Carbohydrate-selective porin
-------------------|-|-----||--------------|||--||--|--|---|||||--  3 [R] COG3668 Plasmid stabilization system protein
---------------------------||--------------------|-----|-------|--  3 [R] COG3687 Predicted metal-dependent hydrolase
-----------------|||-----|-----------|-----------|--------||||||||  3 [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain
--|----------------|-------------------------|--||-----|---|--|---  3 [S] COG4104 Uncharacterized conserved protein
------------------------------------------|||||-||||-------||-|---  3 [E] COG4160 ABC-type arginine/histidine transport system, permease component
-----------------|--|-|||||||-||-||||-||--|||||-||||---|||-||||---  3 [E] COG4166 ABC-type oligopeptide transport system, periplasmic component
-|------|-|||----|||||----|------|---|----|||||--|-----|--|||||---  3 [E] COG4177 ABC-type branched-chain amino acid transport system, permease component
------------------------------------------------||-----|---||-|---  3 [T] COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system
------------------------------------------|||||-||||-------||-|---  3 [E] COG4215 ABC-type arginine transport system, permease component
-------------------------------------------------|-----|----|-|---  3 [C] COG4313 Protein involved in meta-pathway of phenol degradation
------------------------------------------|||||--|-|---|----------  3 [S] COG4575 Uncharacterized conserved protein
------------------------------------------|||||-||---------||-|---  3 [E] COG4598 ABC-type histidine transport system, ATPase component
------------------------------------------|||||-||--------||------  3 [P] COG4771 Outer membrane receptor for ferrienterochelin and colicins
------------------------------------------|||||--|---||-----------  3 [P] COG4773 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid
------------------------------------------|||||-|||||--|-------|--  3 [U] COG4795 Type II secretory pathway, component PulJ
---|--|||--|-||--|--||----||||------||-----------|-----|---|||||||  3 [I] COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
---|||--||-||----|||||----||||||--||||----|||||--|-----|---|||||--  3 [MR] COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily
------------------------------------------|||-|--|---------||||---  3 [S] COG5457 Uncharacterized conserved small protein
--------------------------|---------------|||----|-----|----------  3 [Q] COG5517 Small subunit of phenylpropionate dioxygenase
|||-||--||-|-||-||||-|----|||-||--|||||---|||||--|--||||---|||||--  2 [P] COG0004 Ammonia permease
|||||||||||||||||||||||||||||||||||||||||||||||-||||||||||||||||||  2 [E] COG0006 Xaa-Pro aminopeptidase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||---|||||||  2 [J] COG0009 Putative translation factor (SUA5)
|||-||--||---||-||||-|----||||||-|||||----||||||||||||||||||||||--  2 [E] COG0019 Diaminopimelate decarboxylase
||||||||||||||||||||||||||||||-|||||||||||||||||||||||||||||||||||  2 [J] COG0024 Methionine aminopeptidase
|||-||||||||||--|-||-|||------------||----|||||-||-|-|||||||||-|||  2 [H] COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases
---------|---||-||||||||||||||||||||||||||||||||||||||||||||||||||  2 [J] COG0050 GTPases - translation elongation factors
|||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||--  2 [E] COG0069 Glutamate synthase domain 2
|||||||||||||||-||||-|---|||||||||||||--|-||||||||||||||--||||||--  2 [E] COG0078 Ornithine carbamoyltransferase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  2 [E] COG0107 Imidazoleglycerol-phosphate synthase
---|||--|-|||||-|-||-|----||||----||||----||||||-|--|--|---|||||||  2 [O] COG0109 Polyprenyltransferase (cytochrome oxidase assembly factor)
--||------|||||---|--|||--||||----||||----|||||-||||||||||||||||||  2 [C] COG0114 Fumarase
||||----|||--||-||||||----||||||||||||----|||||-||||||||||||||||||  2 [EH] COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  2 [E] COG0118 Glutamine amidotransferase
|||----||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  2 [EG] COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase
|||||-|||||||||-||||-|||--||||||-|||||----||||||||||||||||||||||||  2 [E] COG0136 Aspartate-semialdehyde dehydrogenase
||||||||||||||||||||||||||||||||||||||----||||||||||||||||||||||||  2 [H] COG0142 Geranylgeranyl pyrophosphate synthase
--||||||--|||||----|-|----|||||---|-||----|||||-|||----|---||||---  2 [E] COG0160 4-aminobutyrate aminotransferase and related aminotransferases
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [J] COG0162 Tyrosyl-tRNA synthetase
|||||||||||||||-||||||----||||||||||||----||||||||||||||||||||||--  2 [F] COG0167 Dihydroorotate dehydrogenase
||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||--  2 [E] COG0169 Shikimate 5-dehydrogenase
-||||-||-||||||---||||----|||-|-----||----||||||||--||||---|||||--  2 [EH] COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes
--||||--|----|||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
--||||--|----|||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  2 [J] COG0223 Methionyl-tRNA formyltransferase
------------------|--|----||||-----|------|||||-||||---|---|||||||  2 [F] COG0232 dGTP triphosphohydrolase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  2 [J] COG0242 N-formylmethionyl-tRNA deformylase
|||||||||||||||-----||----||||||||||||----|||||-|||-||||||||-|----  2 [EJ] COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  2 [J] COG0254 Ribosomal protein L31
-------------||-||||-||||||||||||||||||||||||||||||||||||||-||||||  2 [J] COG0257 Ribosomal protein L36
--|----------|||-|--||||--||||||||||||||||||||||||||||||---|||||-|  2 [H] COG0262 Dihydrofolate reductase
|-||------||-||-||||||||||||||||||||||----||||||||||||||||||||||||  2 [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
--|||||||-|||||--|||-|----|||-|||-||||----|||||-||||||||--||||||||  2 [C] COG0281 Malic enzyme
--|--------|-|--|-||||||--|||----|--|-----|||||-||||---|---||-|---  2 [G] COG0296 1,4-alpha-glucan branching enzyme
--|----|---|-|||---||-----||||||||||||-----------|-|---|---||-||--  2 [R] COG0300 Short-chain dehydrogenases of various substrate specificities
----------||-||-|-||||----||||||||-|||----|||||-|||||--|||||||||||  2 [H] COG0302 GTP cyclohydrolase I
|||||||||||||---|-||-|----|||||---||||----|||||-||||---|||||||||--  2 [H] COG0303 Molybdopterin biosynthesis enzyme
-------------|||--|||---|||||||----|||----|||||||||||--||||-|-|-||  2 [O] COG0326 Molecular chaperone, HSP90 family
-------------||-||||||||--||||||||||||----|||||-||||||||||||||||||  2 [I] COG0331 (acyl-carrier-protein) S-malonyltransferase
--|||||||-|||||--|||||||--|---|--|||||----|||||--|||-|||||--||-|--  2 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase
||||--||-|------|||||||||||||||---||||-|--|||||-||||||||||||||||||  2 [U] COG0342 Preprotein translocase subunit SecD
--|-|||||----||-|-||||----||||||-|||||----|||||-||||||||||||||||--  2 [H] COG0352 Thiamine monophosphate synthase
-------------|||||||-||||||||--|-||||-----||||||||||||||||-|||||--  2 [G] COG0364 Glucose-6-phosphate 1-dehydrogenase
--|-||----|--||--|||-|----|||-||||||||-|--|||||-||-----|---||-||--  2 [G] COG0366 Glycosidases
|-||||--|-|||||-||||-|----||||-|--||||----|||||-||-|||||||||||||||  2 [C] COG0372 Citrate synthase
--||-------|-||---|||-----|||-|||||||||||||||||-||-|-|||---|||||--  2 [L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair
|-||----|----||-|-||-|----|||-||||||||----|||-|-||-|||||--||||||--  2 [T] COG0394 Protein-tyrosine-phosphatase
---|||||--|||----|||-|--|-||||||||-|||-||||||||-||-||--|---||||---  2 [G] COG0395 ABC-type sugar transport system, permease component
||-----|-||-----||||----|-|||-|--|--|-----|||||-||-|-||||||-||||--  2 [M] COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis
---|||||---||||-||||-|-----|||----||||----|||||--|--|-||---|||||--  2 [E] COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain
--|-||-----|-||-||||||----||||||||||||----|||||-||-||--|---|||||--  2 [G] COG0406 Fructose-2,6-bisphosphatase
-|------|-|||----|||||-----------|--------|||||--|-----|--|||||---  2 [E] COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
---|--||--|||||-||||-|----|||||---||||----||||||||--||||||||||||--  2 [H] COG0413 Ketopantoate hydroxymethyltransferase
--|---||-----||-||||||||--|||||-----||----|||||-||-|||||||||||||||  2 [D] COG0424 Nucleotide-binding protein implicated in inhibition of septum formation
---|----|----||---|-|-----|---------------|||||--|---------|-|-|--  2 [C] COG0427 Acetyl-CoA hydrolase
--|----------||-||--||||||----|-----||||||||||||||||||||||||||||||  2 [O] COG0466 ATP-dependent Lon protease, bacterial type
-|||||||--||||||-|||||||-|||||||||||||||||||||||||||||||--||||||--  2 [G] COG0469 Pyruvate kinase
||----||-|||-||-||||||||||||||||||||||----|||||||||||||||||||||-||  2 [M] COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase
|||-|--------||||-|||-----||||||||-||||||||||||--|----------|||---  2 [P] COG0474 Cation transport ATPase
|||-|||||-|||||-|-||-|---|-|||||--||||----|||||-|||-||||||||||||||  2 [P] COG0475 Kef-type K+ transport systems, membrane components
|-|||||||-|||||||-||||----|||||--|||||----|||||-||||||||||||||||--  2 [H] COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [J] COG0480 Translation elongation factors (GTPases)
--|-||||--|-|||||||--|--|-||||||--||||----|||||-||--|--|--||||||||  2 [ER] COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
||||--||-||||||--|||||--|||||-||||||||||||||||||||||-||||||||||---  2 [F] COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins
||||||||||||||||||||-|||||||||||||||||||--||||||||||||||||||||||||  2 [F] COG0504 CTP synthase (UTP-ammonia lyase)
||-|||||-|--|||-||||||-|-|||||||||||||----||||||||||||||||||||||--  2 [F] COG0516 IMP dehydrogenase/GMP reductase
|||||||||||||---|--|-|----|||||---||||----|||||-||||---|||||||||--  2 [H] COG0521 Molybdopterin biosynthesis enzymes
-------||---|||-|-|--|-----||-|-----||----||||||||--|--|--|-||||--  2 [P] COG0529 Adenylylsulfate kinase and related kinases
|||||||||||||---||||-|-----||-||--|-||-----------|-----|----|-|---  2 [R] COG0535 Predicted Fe-S oxidoreductases
||||||-||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  2 [E] COG0547 Anthranilate phosphoribosyltransferase
|||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||-|  2 [E] COG0548 Acetylglutamate kinase
--||-||||--|||||-|||||||--|||-||||-|||--|||||||-|||||-------|-----  2 [KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family
|-|||||||-|||||||||||-|||||||||||||||||||||||||-||||||||||||||||||  2 [I] COG0558 Phosphatidylglycerophosphate synthase
--||--|||----|||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [F] COG0563 Adenylate kinase and related kinases
|-------|--|-|||-||-||---|----||||||||-|||||||||-||||--|---|||||--  2 [G] COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0587 DNA polymerase III, alpha subunit
--|----------||||-||-|||--||||||-|||||----||||||||||||||---|||||||  2 [FJ] COG0590 Cytosine/adenosine deaminases
----------------||||-|||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0593 ATPase involved in DNA replication initiation
||||||||||||----|-|||---------||||||||----|||||-||||||||||||||||||  2 [O] COG0602 Organic radical activating enzymes
|-||||----|||||||-||-|||-|||||||||||||----||||||||||||||||||||||||  2 [P] COG0605 Superoxide dismutase
-||||||||-|||----|||||----||||||||||||----|||||-||||---|||||||||--  2 [P] COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component
|||||||||-|-|---|||||||||-||||-----|||----||||||||||||||||||||||||  2 [OU] COG0616 Periplasmic serine proteases (ClpP class)
-------------|||||||||||||||||||||||||----||||||||||||||||||||||||  2 [J] COG0617 tRNA nucleotidyltransferase/poly(A) polymerase
|||||||||||||---||||||-||-|||||---|-||----||||||||||||||||||||||||  2 [J] COG0621 2-methylthioadenine synthetase
--||||||--|||||--|--||----||||||||||||----|||||-||||||||||||||||--  2 [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases
----------------|||||||||||||-|||||||||---||||||||||||||||||||||||  2 [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases
-|||||||||||||||-|||||--------||-|-|||----||||||||||||||--|||-||--  2 [T] COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases
|-||---------|||--||||--|-||||||||||||----|||||-||||||||||||||||--  2 [O] COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  2 [U] COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase)
---|||||--||||||-||-------||||||||||||----|||||--|-----|---|||||--  2 [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase
--|--|--|--|-||--|||-|--|-|||||||-||-|----|||||-||--|--|---||-||--  2 [I] COG0657 Esterase/lipase
-------------|------------|---------------|||||-|||||-------------  2 [G] COG0676 Uncharacterized enzymes related to aldose 1-epimerase
||||||||||||||||||||||||||||||||||||||-|--||||||||||||||||||||||||  2 [U] COG0681 Signal peptidase I
|-||----|----|||-|||-|----|||||||||||-----|||||-||||||||---|||||||  2 [O] COG0695 Glutaredoxin and related proteins
---|---------||-|-||-|----|----|--||||----|||||-|||-|--|---|||||--  2 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epimerases
-------------||----|-|----|----|-|--------||||||||||||||------||--  2 [E] COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase
--|--|-|-|---|||-|||||||---|||||||||||----|||||-||--|--|||-|||||--  2 [G] COG0726 Predicted xylanase/chitin deacetylase
----------------|||||||||||||||-----------||||||||||||||||||||||||  2 [R] COG0728 Uncharacterized membrane protein, putative virulence factor
----------------|---|---------------------|||||-||||||||---|||||--  2 [M] COG0729 Outer membrane protein
----------------||||----||----||||-|||----||||||||||||||||||||||||  2 [M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)
-----------------|||||----|||||-----||-------|-||||||--|||||||||--  2 [E] COG0757 3-dehydroquinate dehydratase II
----------------||||||||------||||||||----||||||||||||||||||||||||  2 [I] COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases
----------------|-||-------|||------------|||||-||||||||||||||||||  2 [Q] COG0767 ABC-type transport system involved in resistance to organic solvents, permease component
----------------||||||||||||||||||||||----||||||||||||||||||||||||  2 [D] COG0772 Bacterial cell division membrane protein
----------------||||||||||||||||||||||----||||||||||||||||||||||||  2 [M] COG0773 UDP-N-acetylmuramate-alanine ligase
----------------|-||||||--|||-||||||||----|||||-||||||||||||||||--  2 [I] COG0777 Acetyl-CoA carboxylase beta subunit
--------------|-|-||||--||||||||||||||----|||||-||||||||||||||||||  2 [M] COG0787 Alanine racemase
---|------------|-||-|----|||-------||----|||-|-|||||--|||||||-|--  2 [F] COG0788 Formyltetrahydrofolate hydrolase
----||----||----||||||||||----|---||||----|||||-||||||||||||||||||  2 [M] COG0793 Periplasmic protease
-----------------|||||||||----------------|||||-||||||||||||||||||  2 [R] COG0795 Predicted permeases
----------------|-||----||----|-----------|||||-||||||||||||||||||  2 [M] COG0797 Lipoproteins
-----------------|||----|-----||||--||----|||||-||||||||||-|||||--  2 [G] COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase
-------------||-||||||||--||||||||||||----|||||-||||||||||||||||-|  2 [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase
|-||--|||-|-|---|||||||||-||||||||||||-------||--|||-||---|||-|-||  2 [P] COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin
----||--|----||-||||||||--||||||-||-||----||||||||||||||||||||||--  2 [H] COG0807 GTP cyclohydrolase II
----------------||||||--|-|||-|||||||||---||||||||||||||||||||||--  2 [R] COG0820 Predicted Fe-S-cluster redox enzyme
--|-----|---------||--||------------------|||||-|||||--|||||||||||  2 [U] COG0823 Periplasmic component of the Tol biopolymer transport system
-------------||---------------||--|||-----|||||--|-----|||--------  2 [E] COG0833 Amino acid transporters
--||||--|-|||---|-||-|-----||-------------||||||-|--||||||||||||||  2 [C] COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A)
---|------||||--|-||-|----||||----||||----||||||-|--|--|---|||||||  2 [C] COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1
------||||||||||||--||----|||||-|-||||-|--|||||-||-|---||||----|--  2 [K] COG0846 NAD-dependent protein deacetylases, SIR2 family
----------------|-|||---------------------|||||-|||||||||||---||--  2 [M] COG0859 ADP-heptose:LPS heptosyltransferase
----------------|-|||||||||||||---||||----||||||||||||||||||||||--  2 [M] COG0860 N-acetylmuramoyl-L-alanine amidase
---|||||---||||-||||-|-----|||----||||----|||||--|--|-||---|||||--  2 [E] COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain
--||||-||-|||---|-||-|----|||-----||||----||||||||--||||||||||||||  2 [CP] COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit
|||-|||||||||----|||||-----||-||-----|----|||-|-||------------|---  2 [C] COG1032 Fe-S oxidoreductase
-|||||||||||-------|----------------------|||||-||---||-----|-|---  2 [C] COG1042 Acyl-CoA synthetase (NDP forming)
--||----------|--|||------||||||||||||----||||||||||-|||||||||||--  2 [E] COG1045 Serine acetyltransferase
|||||||||||||-------||--|-----------------|||||-|||||||||||-------  2 [O] COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2
--||||----|||||-|----|----||||||--|||-----|||||-||--||||---|||||||  2 [C] COG1048 Aconitase A
-------------||-|||||---||||||||||||||||||||||||||--||||||||||||--  2 [H] COG1057 Nicotinic acid mononucleotide adenylyltransferase
--|-||----|||||---||------||||-||||-||----|||-|--|--|||||||||||---  2 [R] COG1064 Zn-dependent alcohol dehydrogenases
--------|---|||--|||----|||||-||-|||||----|||||--|||---|---||||---  2 [G] COG1070 Sugar (pentulose and hexulose) kinases
--------|----||---||-|----|---|---|-||-|--------||--|--|----------  2 [R] COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold
-------------|||--|-----------------------||||||||||-|||--||||||||  2 [O] COG1076 DnaJ-domain-containing proteins 1
--------------------||||-||---||||||||-|||||||||||||||||------||--  2 [G] COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)
|||---||||-|-----|||------|||||-|-||||----|||||--|-----|---|||||--  2 [G] COG1082 Sugar phosphate isomerases/epimerases
|-||-||||--||---|-||||----|||||||---||----|---|--|--||||---||-||||  2 [M] COG1091 dTDP-4-dehydrorhamnose reductase
--|-----|----||||||||||||-||||||||||||----||||||||||-|||||||||||||  2 [E] COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes
|-||--|||-|-|---|||||||||-||-|||||||||----||||||||||-||---|||||-||  2 [P] COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components
|||||||||||||||||||||||||||||||||||||||-||||||||||||||||||||||||||  2 [G] COG1109 Phosphomannomutase
|||||-||||-|-||||||-|------||||---|---|||||||-|--|--|---|--------|  2 [L] COG1112 Superfamily I DNA and RNA helicases and helicase subunits
--------------------|-|||-|---|-|||-|-----|||||-||||--------------  2 [E] COG1114 Branched-chain amino acid permeases
-||||||||--||----|||||----|---|-|||||||-|||||||-||||---|||||||||--  2 [PH] COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components
|-||--|||-|||---|||||||||-|--|||||||||----||||||||||-||---|||||-||  2 [P] COG1121 ABC-type Mn/Zn transport systems, ATPase component
----------------|-||-------|||------------|||||-||||||||||||||||||  2 [Q] COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component
--|-----|-------|-||------|||||||-||||--------|-||-||||---|-||||||  2 [GM] COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component
------------------||||-||-|---||||||||----|||||-||||||||||||||||--  2 [P] COG1135 ABC-type metal ion transport system, ATPase component
----------------||----||||----|----|||----||||||||-----|||||||||--  2 [NU] COG1157 Flagellar biosynthesis/type III secretory pathway ATPase
--------|----------|||-----||-|||||||-----|||||--|-----|||-||||---  2 [E] COG1174 ABC-type proline/glycine betaine transport systems, permease component
---|||||--|||----|||-|--|-||||||||||||-||||||||-||-||--|---||||---  2 [G] COG1175 ABC-type sugar transport systems, permease components
---|--||--|-|-----||||--|-|------|---|----|||||-||||-|||--|||||---  2 [P] COG1178 ABC-type Fe3+ transport system, permease component
||||----||---||-----|-||-|-||||-----||-----------|--|||||||||||-||  2 [I] COG1183 Phosphatidylserine synthase
-------------||-|||||||||||||||||-||||----||||||||||||||||||||||||  2 [J] COG1186 Protein chain release factor B
||||||||--|||||||-|||-----|||-||||||||----|||||-||||||||-------|--  2 [KL] COG1199 Rad3-related DNA helicases
|-|-||||||||-||||-||------|---|||-||||----|||||--|-----|---|||||-|  2 [M] COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
--|---|---||-|||||-|-|----|--||||||||-----|||||--|-|||||--||||||--  2 [P] COG1230 Co/Zn/Cd efflux system component
-||------|------|-------------------------|||||-||||||||--||||||||  2 [S] COG1238 Predicted membrane protein
--|-------------|----------||-|---|-||----|||||--|-----|---||-||--  2 [C] COG1251 NAD(P)H-nitrite reductase
---|-------|-||---||-|----||||-|--||||----|||||-|||----|---||||---  2 [C] COG1252 NADH dehydrogenase, FAD-containing subunit
--||---------||-|||||||||||||-|||||||-||||||||||||||||||||||||||||  2 [R] COG1253 Hemolysins and related proteins containing CBS domains
--|-----------|---||--||---||-------||----------||-|||||---|||||--  2 [S] COG1262 Uncharacterized conserved protein
|-||--||--|-|---|||||||||||||-||||||||-----||||-||-----|------||--  2 [R] COG1266 Predicted metal-dependent membrane protease
--------------------|---|-|-----||||||-|--|||-|-||--------|||||---  2 [P] COG1283 Na+/phosphate symporter
----------------||------||----|----|||----|||||-||-----|||||||||--  2 [N] COG1291 Flagellar motor component
--|-------------|-||||||--||||||||||||-|--|||||-||||||||||||||||||  2 [S] COG1295 Predicted membrane protein
|||||||||||||||---||-|--||||||-||||||-----|||||-||||-||----|||||||  2 [C] COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
|-|||||||||||||||-||-|-----||--------------||||--|-----|----------  2 [R] COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily
-----------------|----||||----|-----||----||||||||-----||||---|---  2 [NU] COG1317 Flagellar biosynthesis/type III secretory pathway protein
----------------||------||----|----|||----|||||-||-----|||||||||--  2 [N] COG1344 Flagellin and related hook-associated proteins
--|---||------------||--------||--|-||----|||||-||||-|||-----|----  2 [M] COG1346 Putative effector of murein hydrolase
||||--|||||-|----|-|||--------||||||||||--|||-|--|----------|-----  2 [G] COG1363 Cellulase M and related proteins
-----------------|------------|||-|||-----|||-|-||||-||-|||||-|---  2 [M] COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
-----------------|||------|||||-----||----|||-|-||---|||---||||---  2 [S] COG1376 Uncharacterized protein conserved in bacteria
--|---||------------||--------||--|-||----|||||-||||-|||-----|----  2 [R] COG1380 Putative effector of murein hydrolase LrgA
----------------||||||--||||||||||||||||--||||||||||||||||||||||||  2 [S] COG1385 Uncharacterized protein conserved in bacteria
-------------------|||----|--||||||||||-|||||||-||||||||--||||||--  2 [P] COG1393 Arsenate reductase and related proteins, glutaredoxin family
--||----|-|-|||||-||||----|||||-||--||||------|-||--||||--|||-|---  2 [O] COG1404 Subtilisin-like serine proteases
||||-----|--------||-------||--------------------|-----|---||||---  2 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases
----------------||||-|----|---||--||------|||||-||||||||---|||||||  2 [S] COG1434 Uncharacterized conserved protein
-------------||-----|-||------------------|||||-||||||||----|-|---  2 [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase
----------------|-||-------|||------------|||||-||||||||||||||||||  2 [Q] COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component
-----------|--|--|||-|---|||||||---|||----|||||-||||||||---|||||||  2 [G] COG1472 Beta-glucosidase-related glycosidases
--||||||---|-----|||||----|||-||-|||||----|||----|||---|--||||||--  2 [R] COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase
||-|--|||-|||---|--|-|||||||||||||||||----|||||-||--||||||||||||||  2 [K] COG1475 Predicted transcriptional regulators
--|||||||||||||-||||||--|||||-||||||||||||||||||||-|||||--|||||---  2 [H] COG1488 Nicotinic acid phosphoribosyltransferase
---------------------|||------------||----|||||-||||||||||||||||||  2 [O] COG1495 Disulfide bond formation protein DsbB
----------------|-||||||-||||||---|-||----|||||-||||||||--||||||||  2 [S] COG1496 Uncharacterized conserved protein
---|--||-||||---|||||-||--|||||----|-|----||||||||||||||---|||||||  2 [J] COG1530 Ribonucleases G and E
-----------------|------------------|-----|||-|-||-----------|----  2 [Q] COG1535 Isochorismate hydrolase
-------------||---||||||--||||||||||||----|||||-||||||||||||||||--  2 [H] COG1539 Dihydroneopterin aldolase
---|------------||||||----|||||-||-||||||||||||-||--||||||||||||--  2 [R] COG1546 Uncharacterized protein (competence- and mitomycin-induced)
--------------------|-||--||||------------|||||-||||||||||||||||||  2 [M] COG1560 Lauroyl/myristoyl acyltransferase
--||||||----|---||--||-----||------|||--------|--|-----|---|||||--  2 [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold
----------------||------||----|-----||----|||||-||-----||||-------  2 [N] COG1580 Flagellar basal body-associated protein
-|--|||||-|||---||------------|-----||----||||||-|--|--|----------  2 [E] COG1586 S-adenosylmethionine decarboxylase
------------------||-------|||-------|----|||||--|--||||---|||||--  2 [P] COG1613 ABC-type sulfate transport system, periplasmic component
---|----|-||||--|-||-|----||||----||||----||||||-|--|--|---|||||||  2 [C] COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2
-------------|||-----|--|||---------------|||||-||||||||---|||||--  2 [L] COG1643 HrpA-like helicases
-------------------|-|--||---------||-----|||-|-||-|||||---|||||--  2 [S] COG1652 Uncharacterized protein containing LysM domain
---|||||--|||----|||-|--|-||||||||-|||----|||||-||-||--|---||||---  2 [G] COG1653 ABC-type sugar transport system, periplasmic component
--|-----|-------|-||------|||||||-||||--------|-||-||||---|-||||||  2 [GM] COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component
|-|-------------||--|---------|----|||--------|-||-----|---||-|---  2 [S] COG1683 Uncharacterized conserved protein
--------------------|-||||||||||||||||----|||||-||||||||---|||||||  2 [M] COG1686 D-alanyl-D-alanine carboxypeptidase
|||||||||||||--|||-|-|----|||-|------|----|||-|--|-----|----------  2 [S] COG1690 Uncharacterized conserved protein
--|---|||||||---|||||||||||||-||--||||----|||||-|||||------|||||-|  2 [R] COG1694 Predicted pyrophosphatase
-||--------------|--|---|-------||-|--||---|||---|-|---|---|||||--  2 [S] COG1704 Uncharacterized conserved protein
|--------|--------||-------||||----|||----------|||--|||||||||||||  2 [S] COG1714 Predicted membrane protein/domain
--------------------||----||||||||||||----|||||-||||-|||||||||||--  2 [E] COG1760 L-serine deaminase
----||---------------|----|----|--|||---|||||-|-||--|--|---|||||--  2 [O] COG1764 Predicted redox protein, regulator of disulfide bond formation
-||-||||-|-||---||---|----|||-|----|-|--|||||||-||---|||---||-||--  2 [O] COG1765 Predicted redox protein, regulator of disulfide bond formation
||-----||--------||||---|--||-|-----------|||-|--|--||||-------|--  2 [C] COG1773 Rubredoxin
--------|--|--------||----|||-|-|---||----|------||----|||-|||||-|  2 [I] COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit
--|-|||||-|||---||-|-|------------||||----|||||-||-|---|---||-||--  2 [S] COG1801 Uncharacterized conserved protein
------|||-------|-|||---------|-----|-----|||||--|--||||---|||||--  2 [M] COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
--||||--|||||---|-||-|----||||----||||----|||||-||||||||||||||||||  2 [U] COG1826 Sec-independent protein secretion pathway components
|-|-|-|||-|||-|-||||||----||||||-|||||----|||||--|-|-|||---|||||||  2 [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family
--|-------------|----|--------------------|||||-||-|---|||||--|---  2 [P] COG1858 Cytochrome c peroxidase
----------------||----||||----|----|||----||||||||-----|||||||||--  2 [NU] COG1886 Flagellar motor switch/type III secretory pathway protein
---|--|||-|-|||-|--|------|||-|||-||||----|||||-||-----|------||--  2 [H] COG1893 Ketopantoate reductase
----||-----|-||----|||----||||||-|||||----|||||--|||||||---||||---  2 [P] COG1914 Mn2+ and Fe2+ transporters of the NRAMP family
||||||||--||----|||||-----||--|||--|||-------||--|-----||||||||---  2 [S] COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain
-------------|-|----------||||------------|||||-|||||------|||||--  2 [I] COG1946 Acyl-CoA thioesterase
-----------||||---------------------|-----|||||--|-----|----||||--  2 [FH] COG1953 Cytosine/uracil/thiamine/allantoin permeases
----------|||--------|-----||-------||----|||----|-----|---|||||--  2 [O] COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family
------------------|||------||||--|||||----|||||-||||---|----|-----  2 [E] COG1982 Arginine/lysine/ornithine decarboxylases
----------------|-|||----------------|----|||||-||-|||||||||||||--  2 [H] COG1995 Pyridoxal phosphate biosynthesis protein
---|---------||--|-|||--------|---||-|----|||||-||-----|---|||||--  2 [E] COG2008 Threonine aldolase
--------------------||-||-|---||||||||----|||||-||||||||||||||||--  2 [P] COG2011 ABC-type metal ion transport system, permease component
---|||--|-|||||--|--||----|||||-----||----|||-|--|--||||---|||||--  2 [C] COG2025 Electron transfer flavoprotein, alpha subunit
--||||--|-|||---|--|-|----|||-------|-----|||||--|-|---|--||||||--  2 [R] COG2041 Sulfite oxidase and related enzymes
-----------|--------||----|||-|-|---||----|------||----|||-|||||-|  2 [I] COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit
||-|||--||||------|||---------|----|----------|--|-----|---||||---  2 [H] COG2073 Cobalamin biosynthesis protein CbiG
|---||----||||------------|||-------||----|||-|--|-----|---||-|---  2 [R] COG2079 Uncharacterized protein involved in propionate catabolism
------------------||----------||||||||----|||||-||||---|---|||-|--  2 [R] COG2081 Predicted flavoproteins
---|||--|-|||||--|--||----|||||-----||----|||-|--|--||||---|||||--  2 [C] COG2086 Electron transfer flavoprotein, beta subunit
--|-||||||||||--||--||-----||---|-||------|||-|--|-----|------|---  2 [R] COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1
--|-----|----------|-|----|||||--||-||----|||||--|---|||---|||||--  2 [S] COG2128 Uncharacterized conserved protein
---|---------||----|--------------|-|-----|||-|--|-----|------||--  2 [R] COG2130 Putative NADP-dependent oxidoreductases
---|------|--||-|--|------|||-------||----|||||--|||||||--||||||--  2 [Q] COG2132 Putative multicopper oxidases
----------|-------||-|---|-|||-------|----|||-|--|--|--|---||-||--  2 [G] COG2133 Glucose/sorbosone dehydrogenases
--||||----||--|---||-|----||------|-||----|||||--|--|--|---||-||--  2 [PR] COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases
---------------------------||--|---|||----|||||-||-----|---|||||-|  2 [F] COG2169 Adenosine deaminase
-|----||-|--------|--|---------------------------|-----|----|-|---  2 [O] COG2192 Predicted carbamoyl transferase, NodU family
|-||--||||---||-|--|-------||-|-----||----|||-|-||--|----------|--  2 [R] COG2234 Predicted aminopeptidases
-|-|--||------|--|||||--|||---||||||||-|--|||||-||||-||||||-||-|--  2 [R] COG2252 Permeases
------||-----||-||||||||--|||-||||||||----|||||-||||||||--||||||--  2 [J] COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase
------------------||----------||-|--||||||-||||-||--||||----|-||--  2 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
--|-----|--||-----||||---|||||------||----|--||-||------------|---  2 [R] COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain
------------------|--|-----|||-------------------|-----|---||-||--  2 [S] COG2307 Uncharacterized protein conserved in bacteria
-----------|------|--|-----|||-------------------|-----|---||-||--  2 [S] COG2308 Uncharacterized conserved protein
-||---------------||-|---|-||--|--|-||-----------|-----|----------  2 [S] COG2314 Predicted membrane protein
--|---------------|-||--------------||----|||||-||---|||---|||||--  2 [R] COG2334 Putative homoserine kinase type II (protein kinase fold)
------||--|||-|------|||-----------|-|-----------|-----|---|||||--  2 [E] COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog
---|----|---|-----|--|---------------|----------||-|--------||--||  2 [R] COG2358 TRAP-type uncharacterized transport system, periplasmic component
--------|-||---------|--------------||-------||--|-|--------------  2 [Q] COG2368 Aromatic ring hydroxylase
---|||---|||-----|---|------------|-------|||||-||--|--|--|||||---  2 [R] COG2391 Predicted transporter component
|-||||--|||||||-----------|-------|----------|---|-----|---||||---  2 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog
------------------------------------------|||||-||--|----------|--  2 [E] COG2716 Glycine cleavage system regulatory protein
-------------------|------|||-||--||-|----|||-|--|-----|----|-||--  2 [S] COG2764 Uncharacterized protein conserved in bacteria
--|-----|-------|-||-|--------------|-----------||-----|---||-|---  2 [T] COG2770 FOG: HAMP domain
-|----||-|-|-----|---|---------|||||||----||||||||||-------|||||--  2 [J] COG2813 16S RNA G1207 methylase RsmC
--------------------------||||-|||||-|----|||||-||||-|||---|||||--  2 [L] COG2818 3-methyladenine DNA glycosylase
---------------------|--------|-----------|||||-||||-|||----|---||  2 [R] COG2823 Predicted periplasmic or secreted lipoprotein
--------------------|---------------------|||||-||||||||--|----|||  2 [M] COG2853 Surface lipoprotein
--|----------||---|-----------------||----|||||--|---|||-------|--  2 [E] COG2866 Predicted carboxypeptidase
|||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||--  2 [H] COG2896 Molybdenum cofactor biosynthesis enzyme
|--|------|||||-|--|-|----||||-------|----|||||-||-----|---|||||--  2 [P] COG2897 Rhodanese-related sulfurtransferase
-----------------|------------------------|||||-|||||||||||||-||--  2 [S] COG2908 Uncharacterized protein conserved in bacteria
--------------------|----------||-|--------|--|--||||||----|||||--  2 [K] COG2932 Predicted transcriptional regulator
--------------------------|-------||||----|||||-||||---|---|||||--  2 [R] COG2962 Predicted permeases
------------------------------------------|||||-||---|||----|||-||  2 [M] COG2982 Uncharacterized protein involved in outer membrane biogenesis
----------------|---|-||--|-----||--------------||-----|---||||-||  2 [R] COG2984 ABC-type uncharacterized transport system, periplasmic component
---|||--------------||----------|-|-||-------||-||-----|---|||||--  2 [E] COG2986 Histidine ammonia-lyase
------------------------------------------------||---|||||||||||--  2 [C] COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit
-------------||---||-------||-------------------||-----|---||-||--  2 [I] COG3000 Sterol desaturase
------------------------------------------|||||-||---------|-||---  2 [S] COG3126 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||-------------|--  2 [E] COG3138 Arginine/ornithine N-succinyltransferase beta subunit
------------------------------------------|||||-||----------------  2 [S] COG3148 Uncharacterized conserved protein
------------------------------------------|-----||-----|----------  2 [U] COG3149 Type II secretory pathway, component PulM
-------------------------------|--||------|||||-||----------|-||--  2 [S] COG3152 Predicted membrane protein
--|----------------|------|----|--||------|||||-||---------|||||--  2 [R] COG3153 Predicted acetyltransferase
------------------------------------------|--|--||--|--|------||--  2 [U] COG3156 Type II secretory pathway, component PulK
------------------------------------------------||--||||----------  2 [NU] COG3170 Tfp pilus assembly protein FimV
------------------------------------------|||||--|||-||-----------  2 [S] COG3171 Uncharacterized protein conserved in bacteria
--------------------|-----|---------||--------|-||-|---|---||-----  2 [S] COG3181 Uncharacterized protein conserved in bacteria
------------------||------|---------------------||-----|---||-||--  2 [ER] COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins
---||||||--||------------------------------------|----------------  2 [S] COG3199 Uncharacterized conserved protein
---|--------------------------------------------||---|---------|--  2 [S] COG3205 Predicted membrane protein
--|-----------------|-----------|-||||----------||---||-------||--  2 [S] COG3212 Predicted membrane protein
-------------------------------------------------|||-||-----------  2 [S] COG3219 Uncharacterized protein conserved in bacteria
------------------------------|------------------|||-|||----|--|--  2 [S] COG3220 Uncharacterized protein conserved in bacteria
------------------||----||-----------------------|----------------  2 [N] COG3225 ABC-type uncharacterized transport system involved in gliding motility, auxiliary component
---------------------|---------------------------|---||----|------  2 [P] COG3230 Heme oxygenase
---------------------|-----------------------||-||-|---|-----|----  2 [E] COG3232 5-carboxymethyl-2-hydroxymuconate isomerase
-------------------|-|----|---||--||------|||-|--|-|-------|--|---  2 [S] COG3238 Uncharacterized protein conserved in bacteria
------------------||-------||-------|------------|-----|----|-||--  2 [I] COG3239 Fatty acid desaturase
-------------------|--------------------------|-||-||--|----------  2 [IR] COG3240 Phospholipase/lecithinase/hemolysin
--------|---------|--------|||------------------||-----|---||-||||  2 [I] COG3243 Poly(3-hydroxyalkanoate) synthetase
------------------|------------------------------|-----|--|--|----  2 [C] COG3258 Cytochrome c
------------------|-----------------------|||||--|||---|---|||||--  2 [M] COG3264 Small-conductance mechanosensitive channel
---------------------------||-----------------|-||----------------  2 [U] COG3267 Type II secretory pathway, component ExeA (predicted ATPase)
|-|----------------------------------------------|---|||--|-------  2 [R] COG3271 Predicted double-glycine peptidase
------------------------------------------|||||-||||--------------  2 [KE] COG3283 Transcriptional regulator of aromatic amino acids metabolism
-------------------|----------|-----||----|-----||-----|---|||||--  2 [QK] COG3284 Transcriptional activator of acetoin/glycerol metabolism
------------------||-------|-|------------|||||-||||-|||---|||||||  2 [C] COG3288 NAD/NADP transhydrogenase alpha subunit
------------------|-----------------|---------|--|-----|---||-||--  2 [T] COG3300 MHYT domain (predicted integral membrane sensor domain)
------------------------------------------|||||-||-----|----||||--  2 [R] COG3313 Predicted Fe-S protein
--|----------------||------|||------|-----------||-|--------|-|---  2 [Q] COG3315 O-Methyltransferase involved in polyketide biosynthesis
-------------------|------||||------|-----|||||--|-----|-----||---  2 [Q] COG3319 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases
--|-----|------------------------------------|--||----------|--|--  2 [T] COG3322 Predicted periplasmic ligand-binding sensor domain
--------------------|-----|----------|--------|-||-|---|---||-----  2 [S] COG3333 Uncharacterized protein conserved in bacteria
--|-|------|--|---------------|-----------|||||--|-|---|-------|--  2 [S] COG3384 Uncharacterized conserved protein
-----------------|||-|--|-----|-----------------||--|-------------  2 [KT] COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain
-------------------------------------------|||--||---------|--|---  2 [T] COG3456 Uncharacterized conserved protein, contains FHA domain
--------------|------------------------------|---|-----|--|---||--  2 [R] COG3491 Isopenicillin N synthase and related dioxygenases
------------------------------------------------||------------|---  2 [S] COG3495 Uncharacterized protein conserved in bacteria
-----------|---------------||--------------------|-----|------||--  2 [M] COG3511 Phospholipase C
-------------------------------------------||||-||-----|------|---  2 [S] COG3521 Uncharacterized protein conserved in bacteria
---------------------------------------------|--||-----|------|---  2 [O] COG3531 Predicted protein-disulfide isomerase
-------------------------------------------------|---|||---||||---  2 [S] COG3536 Uncharacterized protein conserved in bacteria
-------------------|--------------------------|--|--|--|-----||---  2 [O] COG3555 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases
--------------------------------||-|------|||-|--|--|--|---|||||--  2 [R] COG3568 Metal-dependent hydrolase
-------------------------------------------------|---------|||||||  2 [R] COG3577 Predicted aspartyl protease
----------------|-------|-----------------|||-|-||-----|----|-|---  2 [KT] COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains
--|-----------|----------|-----|------|----------|-----|---|--||--  2 [F] COG3613 Nucleoside 2-deoxyribosyltransferase
-------------------------------||--|-------|||---||-|--------|----  2 [K] COG3617 Prophage antirepressor
--------------------------|---------------|||||--|||---|----|||---  2 [G] COG3622 Hydroxypyruvate isomerase
--||-----------------|-----||-------|------------|---------|--||--  2 [R] COG3631 Ketosteroid isomerase-related protein
---|---------------||-----|----|--|--|-|--||||---|---------||-||--  2 [P] COG3638 ABC-type phosphate/phosphonate transport system, ATPase component
---------------------|---------------------------|----------|-||--  2 [S] COG3652 Predicted outer membrane protein
-------------------|------|---|-||-|||-----------|-------------|--  2 [K] COG3655 Predicted transcriptional regulator
--|----------------||---------|-|||--|-----------|---------||--|--  2 [L] COG3666 Transposase and inactivated derivatives
--------------------|------||||----|-------------|-----|---||-||--  2 [T] COG3707 Response regulator with putative antiterminator output domain
-------------------|----------------|-----|||-|--|-------------|--  2 [R] COG3729 General stress protein
-------------------------------------------------|--|----------|--  2 [P] COG3746 Phosphate-selective porin
-------------------------------------------------|-----|---|||||--  2 [S] COG3749 Uncharacterized protein conserved in bacteria
------------------------------------------|||||--|||--------------  2 [M] COG3765 Chain length determinant protein
-------------------------------------------------|||-||-----------  2 [S] COG3767 Uncharacterized low-complexity protein
------------------------------------------|||||-||----------------  2 [S] COG3776 Predicted membrane protein
-------------------------------------------------|-----|---||-||--  2 [S] COG3795 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|---|||||--  2 [S] COG3803 Uncharacterized protein conserved in bacteria
----------------|-------------|----|||----|||-|--|-----|----------  2 [KT] COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
|||||||||||||---||||||--|-||||||||||||-||||||||-||-||--|--|||||---  2 [G] COG3839 ABC-type sugar transport systems, ATPase components
--------------------------|---||--||-------------|-----|---||-|---  2 [S] COG3865 Uncharacterized protein conserved in bacteria
-------------||----------------------------------|---------|||||--  2 [R] COG3897 Predicted methyltransferase
---------------------------------------------|---|-----|---||-|---  2 [TQ] COG3916 N-acyl-L-homoserine lactone synthetase
-------------------------------------------------|---------||||---  2 [E] COG3938 Proline racemase
--||--------|-|-|-||||----||||||||||||-----------|---||-------|---  2 [R] COG4122 Predicted O-methyltransferase
---------------------------------------------||--|-----|---||-----  2 [S] COG4125 Predicted membrane protein
--------------------|---------------------|||||-||-----|---||||---  2 [R] COG4172 ABC-type uncharacterized transport system, duplicated ATPase component
------------------------------------------|||||-||-----|||-||||---  2 [R] COG4174 ABC-type uncharacterized transport system, permease component
--|----------------------|-----||--||-----|||||--|-----|---||||---  2 [E] COG4175 ABC-type proline/glycine betaine transport system, ATPase component
--|----------------------|-----||--||-----|||||--|-----|---||||---  2 [E] COG4176 ABC-type proline/glycine betaine transport system, permease component
----------------------||------------------|||||-||||||||--|----|--  2 [OC] COG4232 Thiol:disulfide interchange protein
-------------------------|----------------|||||-||-----|||-||||---  2 [R] COG4239 ABC-type uncharacterized transport system, permease component
---------------------------------------------|---|-----|----------  2 [S] COG4253 Uncharacterized protein conserved in bacteria
-------------------|----------------|------------|-----|----|-|---  2 [S] COG4319 Ketosteroid isomerase homolog
------------------||-|----|||-||||||||-----------|-----|---||-||--  2 [T] COG4585 Signal transduction histidine kinase
--|-------------|---||--||----|-----------||||||||||||||||||||||||  2 [M] COG4591 ABC-type transport system, involved in lipoprotein release, permease component
----------------|----------------------------|---|---------||-||||  2 [R] COG4618 ABC-type protease/lipase transport system, ATPase and permease components
------------------------------------------|||||-||||--------------  2 [M] COG4623 Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein
------------------------------------------|||----|-----|----------  2 [S] COG4676 Uncharacterized protein conserved in bacteria
--------------------------|----------------------|-----|-----|----  2 [R] COG4757 Predicted alpha/beta hydrolase
---|----------------------||||-------------------|-----|---|||||||  2 [I] COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit
------------------------------------------|------|------||--|--|--  2 [P] COG4772 Outer membrane receptor for Fe3+-dicitrate
------------------------------------------|||----|--|----------|--  2 [P] COG4774 Outer membrane receptor for monomeric catechols
----------------|-------------------------|||||-||||||||----------  2 [NU] COG4969 Tfp pilus assembly protein, major pilin PilA
------------------------------------------------||--||||------|---  2 [NU] COG4970 Tfp pilus assembly protein FimT
|||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||--  2 [E] COG4992 Ornithine/acetylornithine aminotransferase
------------------------------------------|||-|--|---------||-|---  2 [G] COG4993 Glucose dehydrogenase
----|------|----------||-------------------------|----------|----|  2 [H] COG5424 Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C
|||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||--  1 [E] COG0002 Acetylglutamate semialdehyde dehydrogenase
|||||||||||||||-||||-------||||-||-|||----|--||--|--|------||-|---  1 [F] COG0005 Purine nucleoside phosphorylase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0012 Predicted GTPase, probable translation factor
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0013 Alanyl-tRNA synthetase
--|----------||-||||-|--|-||||||||-|||----|||||-||||||||--||||||--  1 [E] COG0014 Gamma-glutamyl phosphate reductase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0016 Phenylalanyl-tRNA synthetase alpha subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0018 Arginyl-tRNA synthetase
||||||||||||||||||||||||||||||||||||||----||||||||||||||||||||||||  1 [I] COG0020 Undecaprenyl pyrophosphate synthase
-------------|||||||-||||-||||||||||||||||||||||||||||||||||||||--  1 [G] COG0021 Transketolase
|||||||||||||||---||----------------------|||||-||||--------------  1 [J] COG0023 Translation initiation factor 1 (eIF-1/SUI1) and related proteins
---|||----||-||-||||-|----||||-|||||||----|||||-||||||||---|||||--  1 [F] COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)
-|----||---|------||------|||-------|-----|||||-||-|--------------  1 [F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)
---|--||---|----|-|||------||||----|||----|||||-||--||||---||-||--  1 [H] COG0029 Aspartate oxidase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0030 Dimethyladenosine transferase (rRNA methylation)
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase
|--|---|--|||||-||||||--|-|||-|||||||||||||||||-||||-|||--||||||--  1 [F] COG0035 Uracil phosphoribosyltransferase
-|--||-------||||||||||||-||||||||||||||||||||||||||||||||||||||--  1 [G] COG0036 Pentose-5-phosphate-3-epimerase
||||----||||-||-||||-|----||||||--||||----|||||||||||||---||||||--  1 [E] COG0040 ATP phosphoribosyltransferase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase
||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||--||||||||  1 [C] COG0045 Succinyl-CoA synthetase, beta subunit
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0048 Ribosomal protein S12
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0049 Ribosomal protein S7
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0051 Ribosomal protein S10
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0052 Ribosomal protein S2
||||---||||||||-||||||---||||-||||||||----|||||-||-|---|--||||||||  1 [P] COG0053 Predicted Co/Zn/Cd cation transporters
||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG0054 Riboflavin synthase beta-chain
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0055 F0F1-type ATP synthase, beta subunit
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0056 F0F1-type ATP synthase, alpha subunit
-||---||--||-|--|-||||||--|||-||||--||----|||||-||||-------||-|---  1 [G] COG0058 Glucan phosphorylase
|||----|||||-|--||||-|----||||||-|||||----||||||||||||||||||||||--  1 [EH] COG0059 Ketol-acid reductoisomerase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0060 Isoleucyl-tRNA synthetase
|||||||||||||||||||||---|||||||||||||||-||||||||||||||||||||||||||  1 [G] COG0061 Predicted sugar kinase
|||||||||||||||-||||-|----|||||-----------|||||-||--|--|||||||||--  1 [S] COG0062 Uncharacterized conserved protein
||||||||||||||||||||-|----||||||--|||-----|||||-||--||||||||||||--  1 [G] COG0063 Predicted sugar kinase
||||----||-||||-||||||||||||||||||||||||||-------|---|||||||||||||  1 [J] COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog)
||||--||||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0065 3-isopropylmalate dehydratase large subunit
|||---||||||-||-||||-|----||||||-|||||----||||||||||||||--||||||--  1 [E] COG0066 3-isopropylmalate dehydratase small subunit
|||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||--  1 [E] COG0067 Glutamate synthase domain 1
|||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||--  1 [E] COG0070 Glutamate synthase domain 3
|||||||||||||||-||||-|-----||||---|-||----||||||||--|--|---|||||||  1 [O] COG0071 Molecular chaperone (small heat shock protein)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0072 Phenylalanyl-tRNA synthetase beta subunit
||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||--||||||||  1 [C] COG0074 Succinyl-CoA synthetase, alpha subunit
||||||||||||||--||||-|--------||--|-||--------|-||------||-||-||--  1 [E] COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase
||||||--||||-||-||||-|----||||||-|||||----|||-||||||||||--||||||--  1 [E] COG0077 Prephenate dehydratase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0080 Ribosomal protein L11
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0081 Ribosomal protein L1
||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||--  1 [E] COG0082 Chorismate synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0087 Ribosomal protein L3
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0088 Ribosomal protein L4
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0089 Ribosomal protein L23
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0090 Ribosomal protein L2
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0091 Ribosomal protein L22
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0092 Ribosomal protein S3
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0093 Ribosomal protein L14
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0094 Ribosomal protein L5
---|||||---||||-||||--||--|----|||||||-||||||||-||----------------  1 [H] COG0095 Lipoate-protein ligase A
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0096 Ribosomal protein S8
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0097 Ribosomal protein L6P/L9E
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0098 Ribosomal protein S5
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0099 Ribosomal protein S13
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0100 Ribosomal protein S11
|||||||||||--||||||||||||||||||||||||||-||||||||||||||||||||||||||  1 [J] COG0101 Pseudouridylate synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0102 Ribosomal protein L13
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0103 Ribosomal protein S9
||||||||||||-||-||||||----||||||||||||----||||||||||||||||||||||--  1 [F] COG0104 Adenylosuccinate synthase
|||||||||||||||||-||-||||||||||--|||||----|||||-||||||||||||||||||  1 [F] COG0105 Nucleoside diphosphate kinase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase
||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase
||||||--|||||||-|-||||||--|||||---||||----|||||-||-|||||||||||||||  1 [H] COG0113 Delta-aminolevulinic acid dehydratase
-|----|||||-|-----|-||--------||||||||----||||||||||||||----------  1 [L] COG0116 Predicted N6-adenine-specific DNA methylase
-------------||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG0117 Pyrimidine deaminase
||||||||||||||||--||-|||||----||||||------||||||||||||||---|||||--  1 [G] COG0120 Ribose 5-phosphate isomerase
||--|-||--||-|----||-------||-------------|||||-||||-|||---||||---  1 [R] COG0121 Predicted glutamine amidotransferase
|-||--|||---||||--|--|-----||-|-----||-|--|||||-||--|--|---|||||--  1 [L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0124 Histidyl-tRNA synthetase
||||||||||||||||||||||||||||||-|||||||||||||||||||||||||||||||||||  1 [F] COG0125 Thymidylate kinase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||--  1 [G] COG0126 3-phosphoglycerate kinase
||||||||||||||||||||||||||||||||||||||----|||||-||||||||--||||||--  1 [F] COG0127 Xanthosine triphosphate pyrophosphatase
||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||--  1 [E] COG0128 5-enolpyruvylshikimate-3-phosphate synthase
||||||||||||||||||||||||||||||||||||||||--||||||||||||||--||||||||  1 [J] COG0130 Pseudouridine synthase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0131 Imidazoleglycerol-phosphate dehydratase
-|-----------|--|-|||--|--|||||---|-||----||||||||||||||||||-|||--  1 [H] COG0132 Dethiobiotin synthetase
||||---|||---||-|||||||---||||||-|||||----||||||||||||||||||||||--  1 [E] COG0133 Tryptophan synthase beta chain
||||||-||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1 [E] COG0134 Indole-3-glycerol phosphate synthase
||||||-||||||||-||||-||---|---||-|||||----||||||||||||||||||||||--  1 [E] COG0135 Phosphoribosylanthranilate isomerase
||||||--||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0137 Argininosuccinate synthase
--||||--|----||-||||||----||||||-|||||----||||||||||||||--||||||--  1 [F] COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0139 Phosphoribosyl-AMP cyclohydrolase
||||-----|||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0140 Phosphoribosyl-ATP pyrophosphohydrolase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0141 Histidinol dehydrogenase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0143 Methionyl-tRNA synthetase
-|-|--||||||||||-|||||||--|||-||||||||----|||||-||||||||--||||||--  1 [J] COG0144 tRNA and rRNA cytosine-C5-methylases
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||--  1 [G] COG0148 Enolase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||--  1 [G] COG0149 Triosephosphate isomerase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0150 Phosphoribosylaminoimidazole (AIR) synthetase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||||||||||--  1 [F] COG0151 Phosphoribosylamine-glycine ligase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||||  1 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase
-|--||||-----||||-||||||---|||----|-||----|||||-||||||||||||||||||  1 [H] COG0156 7-keto-8-aminopelargonate synthetase and related enzymes
||||--||||||-|--|||||-----|||||-||-|||----|||||-||||||||||-||-||--  1 [H] COG0157 Nicotinate-nucleotide pyrophosphorylase
---|---------||---||----------------------|||||-||||-||||||-||-|--  1 [G] COG0158 Fructose-1,6-bisphosphatase
||||||-||||||||-||||-||---||||||-|||||----||||||||||||||||||||||--  1 [E] COG0159 Tryptophan synthase alpha chain
|||-||||||||||--|-||-|||------------||----|||||-||-|-|||||||||-|||  1 [H] COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase
||||||||||||||||||||||||-|||||||||||||----|||||-||||||||||||||||||  1 [L] COG0164 Ribonuclease HII
||||||--||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0165 Argininosuccinate lyase
-|-|||----||||||||||||||||||||||||||||-|||||||||||||||||||||||||--  1 [G] COG0166 Glucose-6-phosphate isomerase
||||--||||--|||-||||||--||------||||||-||||||||-||||-||---||||----  1 [P] COG0168 Trk-type K+ transport systems, membrane components
|||||||||||||||-||||||--||||||||||||||||||||||||||--||||||||||||--  1 [H] COG0171 NAD synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0172 Seryl-tRNA synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0173 Aspartyl-tRNA synthetase
-|--||-------||-||||-|||--|||||-||||||----||||||||||-|||||||||||--  1 [G] COG0176 Transaldolase
||||||||||||||||||||||||||||||||||||||----||||||||||||||||||||||||  1 [L] COG0177 Predicted EndoIII-related endonuclease
|-||------------|||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG0178 Excinuclease ATPase subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0180 Tryptophanyl-tRNA synthetase
||||||--|||||||-|-||||||--|||||---||||----||||||||-|||||||||||||||  1 [H] COG0181 Porphobilinogen deaminase
|||-|||||||||||-|||||---------------|------------|--|-------|-|---  1 [J] COG0182 Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0184 Ribosomal protein S15P/S13E
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0185 Ribosomal protein S19
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0186 Ribosomal protein S17
--||||----||-||-|||||||||||||||||||||||||||||||||||||-||||||||||||  1 [H] COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase
-------------||-||||-|--||||||||||||||||||||||||||||-||||||-||||--  1 [G] COG0191 Fructose/tagatose bisphosphate aldolase
-------------||-||||||--||||||||||||||||||||||||||||||||||||||||--  1 [H] COG0192 S-adenosylmethionine synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0193 Peptidyl-tRNA hydrolase
-------------|||||||||||--||||||||||||||||||||||||||||||||||||||||  1 [F] COG0194 Guanylate kinase
|||||||||||||---||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0195 Transcription elongation factor
-------------||-|||||||||-||||||||||||||||||||||||||||||||||||||--  1 [H] COG0196 FAD synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0197 Ribosomal protein L16/L10E
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0198 Ribosomal protein L24
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0199 Ribosomal protein S14
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0200 Ribosomal protein L15
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0201 Preprotein translocase subunit SecY
||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0203 Ribosomal protein L17
||||||||||------||||||--||||||||||||||-|||||||||||||||||||||||||||  1 [D] COG0206 Cell division GTPase
|||-----||---|||----||----||||||||||||-|||||||||||||||||---|||||--  1 [F] COG0207 Thymidylate synthase
---|-------|-||||-|-|||||-||||||||||||-|||||||||||||||||||||-|-|||  1 [F] COG0208 Ribonucleotide reductase, beta subunit
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0211 Ribosomal protein L27
|--|-----||||||-|-|||||||-||||||-|||||--|||||||-||||||||||||||||||  1 [H] COG0212 5-formyltetrahydrofolate cyclo-ligase
--|||||||-||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0215 Cysteinyl-tRNA synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0216 Protein chain release factor A
-------------||-|||||||||||||||||||||||||||||||-||||||||||||||||||  1 [S] COG0217 Uncharacterized conserved protein
-|||--||||---|--||--|---------||||||||||||||||||||||||||||||||||||  1 [R] COG0218 Predicted GTPase
------------------||||||--|||||||||-|||||||||||-||||||||--||||||--  1 [J] COG0219 Predicted rRNA methylase (SpoU class)
-------------||||||||||||-||||||||||||||||||||||||||||||||||||||||  1 [R] COG0220 Predicted S-adenosylmethionine-dependent methyltransferase
|-||||||-|-||||||-||||||--|||||----|-|||||||||||||||||||||||||||||  1 [C] COG0221 Inorganic pyrophosphatase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0222 Ribosomal protein L7/L12
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0224 F0F1-type ATP synthase, gamma subunit
|-||-------|-||---||||--|-|||||||||||||||||||||-||||||||||||||||--  1 [O] COG0225 Peptide methionine sulfoxide reductase
-------------||-|||||||||||||-|||||||||||||||||||||||||||||-||||||  1 [J] COG0227 Ribosomal protein L28
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0228 Ribosomal protein S16
|-||---------||---||||--|-|||-||||||||-||||||||-||||||||||||||||--  1 [O] COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase
-------------||-||||-||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0230 Ribosomal protein L34
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0233 Ribosome recycling factor
--|----------||-||||||||||||||||||||||--||||||||||||||||||||||||||  1 [O] COG0234 Co-chaperonin GroES (HSP10)
||||||||||||||||||||||||||||||||||||||-|||||||||||||||||||||||||||  1 [H] COG0237 Dephospho-CoA kinase
-------------||-|||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0238 Ribosomal protein S18
-|||--||-|---||-||||-|----|||-|--|||||----|||||-||||||||||||||||--  1 [D] COG0239 Integral membrane protein possibly involved in chromosome condensation
|-------|----|||||||||||||||||||||||||||--|||||-||||||||||||||||||  1 [C] COG0240 Glycerol-3-phosphate dehydrogenase
-|--||-------|||--|-|------||-|-----------|||||||||||||||||---||--  1 [E] COG0241 Histidinol phosphatase and related phosphatases
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0244 Ribosomal protein L10
----------------|||||||||-|||||----|||--||||||||||||||||||||||||--  1 [I] COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
-------------|---|--------|---||-||-||-||-||||||||-|---|---|||||--  1 [G] COG0246 Mannitol-1-phosphate/altronate dehydrogenases
--|--------|-|--||||||----|||||------|----|||||-||||||||||||||||||  1 [FP] COG0248 Exopolyphosphatase
--||-|-------|||||||||||||----|||-||||----||||||||||||||---|||||||  1 [L] COG0249 Mismatch repair ATPase (MutS family)
|||||||||||||-|-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0250 Transcription antiterminator
||------||------|||||-||--|||||---||||----||||||||||||||||||||||||  1 [E] COG0253 Diaminopimelate epimerase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0255 Ribosomal protein L29
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0256 Ribosomal protein L18
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0258 5'-3' exonuclease (including N-terminal domain of PolI)
------------|-|||-||||||--||||----|-|||||||||||||||||-||||||||||||  1 [E] COG0260 Leucyl aminopeptidase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0261 Ribosomal protein L21
--|----------||-||||-|--|-||||||||-|||----|||||-||||||||--||||||--  1 [E] COG0263 Glutamate 5-kinase
--------------|-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0264 Translation elongation factor Ts
------------------||-|----||||-||||||||||||||||-||||||||---|||||-|  1 [L] COG0266 Formamidopyrimidine-DNA glycosylase
-------------||-|||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0267 Ribosomal protein L33
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0268 Ribosomal protein S20
---|---------||---||----------------------||||||||||||||---|||||||  1 [T] COG0271 Stress-induced morphogen (activity unknown)
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0272 NAD-dependent DNA ligase (contains BRCT domain type II)
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [M] COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis
----||-------||-|-||-|||--||||-|-|||||----|||||-||||||||||||||||||  1 [H] COG0276 Protoheme ferro-lyase (ferrochelatase)
---|---------|||--||----------------------||||||||||||||---|||||||  1 [O] COG0278 Glutaredoxin-related protein
-|--||----------|-|-|------||-|-----------||||||||||-||-|||---|---  1 [G] COG0279 Phosphoheptose isomerase
--||-------------||-||--|||||-||||||||||||||||||||||||||-|||||||||  1 [C] COG0280 Phosphotransacetylase
--|--------------|||||--|||||-||||||||||||||||||||||-||-|||-|||-||  1 [C] COG0282 Acetate kinase
---------------||||||||||||||||||||||||||||||||-||||||||---|||||||  1 [F] COG0283 Cytidylate kinase
|||||||||||||||-||||||----||||||||||||----||||||||||||||||||||||--  1 [F] COG0284 Orotidine-5'-phosphate decarboxylase
---|||-------||-||||||--|-||||||||||||----||||||||||||||||||||||||  1 [H] COG0285 Folylpolyglutamate synthase
||||---||----------|-------||--|||||--|||-|||-|-|||||||||||-||-|-|  1 [V] COG0286 Type I restriction-modification system methyltransferase subunit
||||||--|||||||-||||-|----||||||-|||||----|||||-||||||||||||||||--  1 [E] COG0287 Prephenate dehydrogenase
|||-----||------||||--||--|||-||-|||||----||||||||||||||||||||||||  1 [E] COG0289 Dihydrodipicolinate reductase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0290 Translation initiation factor 3 (IF-3)
-------------|--||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0291 Ribosomal protein L35
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0292 Ribosomal protein L20
||||||--||---|||--------||----------------||||||||||||||---|||||||  1 [J] COG0293 23S rRNA methylase
|||||||||||||||-||||||||--||||||||||||----|||||-||||||||||||||||-|  1 [H] COG0294 Dihydropteroate synthase and related enzymes
-|----||--||--|-||||||||------||-|--||----|||||-||||---|---||-|---  1 [G] COG0297 Glycogen synthase
--||||----|--||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN
|||||||||||||----|------|-----|||||||||||||||||-||||--------------  1 [H] COG0301 Thiamine biosynthesis ATP pyrophosphatase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0305 Replicative DNA helicase
---|---------||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG0307 Riboflavin synthase alpha chain
--|-||----||-|||--||-|----||||-|||--------|||||-||||||||---|||||--  1 [E] COG0308 Aminopeptidase N
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [R] COG0313 Predicted methyltransferases
|||||||||-|||---|-||-|----|||-----||||----|||||-||||---|||||||||--  1 [H] COG0314 Molybdopterin converting factor, large subunit
|||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||--  1 [H] COG0315 Molybdenum cofactor biosynthesis enzyme
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [R] COG0319 Predicted metal-dependent hydrolase
---|------|||||-|-||-|||--||||----|-||----||||||||||||||---|||||||  1 [H] COG0320 Lipoate synthase
----------|--||---||-|----||||------------||||||||||||||---|||||||  1 [H] COG0321 Lipoate-protein ligase B
|-||------------|||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG0322 Nuclease subunit of the excinuclease complex
--||---------|||||||||||||----||||||||----||||||||||||||---|||||||  1 [L] COG0323 DNA mismatch repair enzyme (predicted ATPase)
-------------||-||||||||||||||||||||||----||||||||||||||||||||||||  1 [J] COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase
--|----------||-||||||----||||||||||||----||||||||||||||||||||||--  1 [R] COG0325 Predicted enzyme with a TIM-barrel fold
||||--||||---|||---|||||||||-|||||||||||--||||||||||-||||||-------  1 [S] COG0327 Uncharacterized conserved protein
---|------|--||---||-|--|-||||----||||----|||||-||||||||||||||||||  1 [L] COG0328 Ribonuclease HI
-------------||-||||||||||----||||||||||||||||||||||||||||||||||||  1 [J] COG0333 Ribosomal protein L32
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0335 Ribosomal protein L19
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0336 tRNA-(guanine-N1)-methyltransferase
----||-|--|||||--|||||||--||||||||||||----||||||||||||||||||||||--  1 [E] COG0337 3-dehydroquinate synthetase
-------------||---||-|----|---------------|||||-||||||||---|||||--  1 [E] COG0339 Zn-dependent oligopeptidases
||||--|||--|-||-|||||||||-||||||||||||----|||||-||||||||||||||||||  1 [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase
||||--||-|------|||||||||||||||---||||-|--|||||-||||||||||||||||||  1 [U] COG0341 Preprotein translocase subunit SecF
|||||||||||||-||||||||||-||---||||||||----||||||||||||||||||||||||  1 [J] COG0343 Queuine/archaeosine tRNA-ribosyltransferase
----------------||||||--------|||||||||||||||||-||||-|||||||||||--  1 [S] COG0344 Predicted membrane protein
|-|-||----|||||-||||-|--|-||||||||||||----|||||-||||||||||||||||--  1 [E] COG0345 Pyrroline-5-carboxylate reductase
|||-----||------||||-|----|||-||---||-----|||||-||||||||---|||||--  1 [E] COG0347 Nitrogen regulatory protein PII
-------------|----||------|||||-----------|||||-|||||------|||||||  1 [J] COG0349 Ribonuclease D
|||||||||||||||-||-|||--|-||||||||||||----|||||-||||||||||||||||--  1 [H] COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase
----------------|-|||||||-||||||||||||||--|||||-||||||||||||||||||  1 [L] COG0353 Recombinational DNA repair protein (RecF pathway)
-------------||-|-||-|----||||------------||||||||||||||---|||||||  1 [R] COG0354 Predicted aminomethyltransferase related to GcvT
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0355 F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit)
--|----------|--|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0356 F0F1-type ATP synthase, subunit a
----------------||||||--|||||||||||||||||||||||-||||||||||||||||||  1 [M] COG0357 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division
|||||||||||||---||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0358 DNA primase (bacterial type)
--------------|-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0359 Ribosomal protein L9
-------------||-|||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0360 Ribosomal protein S6
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0361 Translation initiation factor 1 (IF-1)
-------------|||-||||-||||||||||||||||-|--|||||-||||||||||-|||||--  1 [G] COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase
|||||||||||||-----||||----|||-|----|-|----|||-|-||-----|---||||---  1 [H] COG0368 Cobalamin-5-phosphate synthase
-------------|||--||--||----------|-||----||||||||--|||----|-|-|--  1 [P] COG0369 Sulfite reductase, alpha subunit (flavoprotein)
|||---|||||-----||||-|--------||--||------|||||-||--|--||||----|--  1 [P] COG0370 Fe2+ transport system protein B
||||||--|||||---|-||||||--|||||---||||----|||||-||-||||||||-------  1 [H] COG0373 Glutamyl-tRNA reductase
--|||||||-|||---||||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases
|||-----||----|-|-||||----|||-----|--||---|||||--||----||||||||---  1 [OK] COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase
||||--||||||----|||||-----|||||----|||----|||||-||--||||||-||-||--  1 [H] COG0379 Quinolinate synthase
||-|--||---------|||-|--------||-||||-----|||||-||-|-|||--|-----||  1 [M] COG0381 UDP-N-acetylglucosamine 2-epimerase
|||||||||||||||-|-||-|||--|||||------|----|||||-||-|||||||||||||||  1 [H] COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases
-------------||---||------|----------|----|||-|-||--|--|---||--|--  1 [S] COG0397 Uncharacterized conserved protein
-------------||---||-|||-------|--||||----|||----|--|------||||-||  1 [R] COG0400 Predicted esterase
-------------||---||----------------------|||-|--|---------|------  1 [S] COG0401 Uncharacterized homolog of Blt101
--|-||-------||-|-||-|||--||||----||||----|||||-||-|||||||||||||||  1 [H] COG0407 Uroporphyrinogen-III decarboxylase
-------------||---||----------------------|||||-||--|--|---|||||||  1 [H] COG0408 Coproporphyrinogen III oxidase
-------------||-||||-|----|||||---||||----||||||||--||||||||||||--  1 [H] COG0414 Panthothenate synthetase
|-||-------|-|----||------|-----|-||------||||||||----|----|--||--  1 [L] COG0415 Deoxyribodipyrimidine photolyase
----------------||||||||------|||||||||||||||||-||-|-|||||||||||--  1 [I] COG0416 Fatty acid/phospholipid biosynthesis enzyme
||||||||||||||||---|----------------------|||||-||----------------  1 [L] COG0417 DNA polymerase elongation subunit (family B)
-------------||---|-----------------------||||||||---||||||||-----  1 [F] COG0418 Dihydroorotase
||||||||||||||||||||||--||----||--|||-----|||||-||----------------  1 [L] COG0419 ATPase involved in DNA repair
||||||||||||||||||||||--||||||||--||||----|||||-||----------|-----  1 [L] COG0420 DNA repair exonuclease
||||---|||||----||||||----|||||-----||----|||||-||--||||--|||-||--  1 [H] COG0422 Thiamine biosynthesis protein ThiC
|||---|||-------|||||---------|-----------|||-|--|-----|----------  1 [C] COG0426 Uncharacterized flavoproteins
||||--||--||||||||-|-|---||||------|------|||-|--|---|||--|-|-----  1 [P] COG0428 Predicted divalent heavy-metal cations transporter
-------------|-|--||----------------------|||||-||---|||----------  1 [R] COG0429 Predicted hydrolase of the alpha/beta-hydrolase fold
||||--|||||||||||--|----------------------|||-|--|-----|----------  1 [A] COG0430 RNA 3'-terminal phosphate cyclase
|||---|||||||-|-||||-|-----||-|-----||----|||-|-||---------||-----  1 [S] COG0432 Uncharacterized conserved protein
|||||||||||||---||||-|-----||---|----|----||||---|-|---|---|||||--  1 [R] COG0433 Predicted ATPase
---|---------||---||------|---------------|||-|-||---------||||---  1 [O] COG0435 Predicted glutathione S-transferase
--||---||-|||---|-------------------------|||||-||||---|--|-|-|---  1 [C] COG0437 Fe-S-cluster-containing hydrogenase components 1
|||---||||--|||-||||-|----||||||-|||||----||||||||||-|||--||||||--  1 [E] COG0440 Acetolactate synthase, small (regulatory) subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0441 Threonyl-tRNA synthetase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0442 Prolyl-tRNA synthetase
--|||||||-|||---||--||||-||---|||||||||||||||||-||||---||||||||---  1 [EP] COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
-------------||-||||||||||----||||||||||||||||||||||||||||||||||||  1 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division
||||||||-||||||||||||||||-||||||||||||----||||||||||||||||||||||--  1 [M] COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains
|||||||||||||||-||||||---|||||||||||||----|||||-||||||||||||||||--  1 [H] COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase
||-|--||||------||-|----||-||||-----||----------||-----||||-------  1 [D] COG0455 ATPases involved in chromosome partitioning
||||||--||||-||-||||||----||||||||||||----||||||||-|||||||||||||--  1 [EF] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
||||||||||||||||||||||||||||||||||||||--||||||||||||||||||||||||||  1 [O] COG0459 Chaperonin GroEL (HSP60 family)
|||||||||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1 [E] COG0460 Homoserine dehydrogenase
|||||||||||||||-||||||-|--||||||||||||----||||||||||||||||||||||--  1 [F] COG0461 Orotate phosphoribosyltransferase
|||||||||||||||-||||||--||||||||||||||||||||||||||||||||||||||||-|  1 [FE] COG0462 Phosphoribosylpyrophosphate synthetase
||||||||||||||||--||-|----||||------||-----------|-----|--|||-|---  1 [O] COG0464 ATPases of the AAA+ class
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0465 ATP-dependent Zn proteases
|||||||||||||||||||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG0468 RecA/RadA recombinase
|||||||||||||||||||||||||-||||-|||||||||||||||||||||||||||||||||||  1 [L] COG0470 ATPase involved in DNA replication
||-|--||-||--||-|-|--|||--|---|||||-||----|||||-||||||||||||||----  1 [P] COG0471 Di- and tricarboxylate transporters
|||---||||||-||-||||-|----||||||--||||----||||||||||||||--||||||||  1 [CE] COG0473 Isocitrate/isopropylmalate dehydrogenase
||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||||||||||||  1 [C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [M] COG0481 Membrane GTPase LepA
-------------||-||||||||-|||||||||||||||||||||||||||||||||||||||||  1 [J] COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain
||||--||||||||--||||-|---|||||-|||||||----|-||||||||||||--||||||||  1 [G] COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family
|-||||-------|||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain
-------------||-||||||||||----||||||||||||||||||||||||||||||||||||  1 [R] COG0486 Predicted GTPase
||||||||||||||||||||||----|||||--|||||----|||||-||||||||||||||||||  1 [D] COG0489 ATPases involved in chromosome partitioning
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0495 Leucyl-tRNA synthetase
||||----|||-||--||||-||||-----------------|||||-||||||||||||||||--  1 [R] COG0496 Predicted acid phosphatase
----------------|-||||--|-||||||||||||----|||||-||||||||||||||||||  1 [L] COG0497 ATPase involved in DNA repair
|||||||||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1 [E] COG0498 Threonine synthase
|||||||||||||||-||||------||||-------------------|--|--|---|||||--  1 [H] COG0499 S-adenosylhomocysteine hydrolase
|||------|---||-|||||--|--|||||---|-||----||||||||||||||||||-|||--  1 [H] COG0502 Biotin synthase and related enzymes
||||||--||||-||-||||||----||||||||||||----||||||||-|||||||||||||--  1 [EF] COG0505 Carbamoylphosphate synthase small subunit
---|---------||---||-|----|||-----|-||----|||||--|-|-|||||||||||--  1 [E] COG0506 Proline dehydrogenase
-|-----------||----|-|||-|-||-||||||||-|--|||||||||||||---|||||---  1 [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member
--|---------||||--||||--|-|---||--||||----|||||-||||||||---||-||--  1 [L] COG0514 Superfamily II DNA helicase
|||||||||||||||-||||||-|-|||||||||||||----|||||-||||||||||||||||--  1 [F] COG0519 GMP synthase, PP-ATPase domain/subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0522 Ribosomal protein S4 and related proteins
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0525 Valyl-tRNA synthetase
|||||-|||||||||-||||-|||--||||||-|||||----||||||||||||||||||||||||  1 [E] COG0527 Aspartokinases
|||||||||||||---||||||||||||||||||||||||||||||||||||||||||||||||||  1 [F] COG0528 Uridylate kinase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0532 Translation initiation factor 2 (IF-2; GTPase)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0533 Metal-dependent proteases with possible chaperone activity
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [R] COG0536 Predicted GTPase
---|||--|-|||||-||||-|-----||--|--||||----|||||--|-|---|||-|||||--  1 [C] COG0538 Isocitrate dehydrogenases
-------------||-||||||||||||||||||||||-|--||||||||||||||||||||||||  1 [J] COG0539 Ribosomal protein S1
|||||||||||||||-||||||----||||||||||||----||||||||--||||||||||||--  1 [F] COG0540 Aspartate carbamoyltransferase, catalytic chain
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0541 Signal recognition particle GTPase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)
---|||||--|-|-----|------------||||-----|-|||-|--||---------|-----  1 [E] COG0549 Carbamate kinase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0550 Topoisomerase IA
|||||||||--------|--|-|||-----|||||||||-|||||||||||||||||||-------  1 [L] COG0551 Zn-finger domain associated with topoisomerase type I
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0552 Signal recognition particle GTPase
||||||||||||------||-|-----||-|------|----|||||-||||||||---|||||--  1 [O] COG0555 ABC-type sulfate transport system, permease component
|-||------------|||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG0556 Helicase subunit of the DNA excision repair complex
---|---------||||||||||||-|---||||||||||||||||||||||||||||||||||--  1 [K] COG0557 Exoribonuclease R
||||||--||-||-----||-|--------------------|||||-||||||||---|||||-|  1 [J] COG0565 rRNA methylase
--------|----||-|||||||||||||||||||||||||||||||-||||||||||||||||||  1 [J] COG0566 rRNA methylases
-------------||------|||--||||----|-||----||||||||||||||---|||||||  1 [C] COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes
||||--|||||-|---||||||--||-||---||||||-||||||||-||||-||---||||----  1 [P] COG0569 K+ transport systems, NAD-binding component
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0571 dsRNA-specific ribonuclease
|||||||||||||---||||||--|-|||||--|-||-----|||||-||--||||||||||||||  1 [G] COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase
|||||||||||||||||||||||||||||||||||||||||||||||-||||||||||||||||||  1 [I] COG0575 CDP-diglyceride synthetase
|-||||-------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0576 Molecular chaperone GrpE (heat shock protein)
||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||--  1 [P] COG0581 ABC-type phosphate transport system, permease component
|||||||||--||---||||||||--||||||||||||||--|||||-||||||||||||||||||  1 [L] COG0582 Integrase
|||||||||||||||||----|--------------------|||||-||||----|||-------  1 [S] COG0585 Uncharacterized conserved protein
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)
-----------------||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0594 RNase P protein component
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [MU] COG0597 Lipoprotein signal peptidase
--|||||||-|||---||||||||-||||||||||||||||||||||-||||---||||||||---  1 [EP] COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components
|||||||||||||---|-||----------|---|-||----|||||-||||||||||||||||||  1 [R] COG0603 Predicted PP-loop superfamily ATPase
|--------|------||||||---||||-|-----------|||||-||||||||||||||||-|  1 [O] COG0606 Predicted ATPase with chaperone activity
||||||||||||----|||||||||||---||||||||----|||||-||||||||||||||||||  1 [L] COG0608 Single-stranded DNA-specific exonuclease
||||---||----------|-----------||-||--|||-------||||||--|||-||-|-|  1 [V] COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
|||||||||||||---|-||------||||------||----||||||||||||||--|----|--  1 [H] COG0611 Thiamine monophosphate kinase
||||----|--||---||||-|--------|------|----|||||-||||-|||----------  1 [R] COG0613 Predicted metal-dependent phosphoesterases (PHP family)
|||||||||||||||-||-----|--||||-|-|||||----||||||||||||||--||--||--  1 [E] COG0620 Methionine synthase II (cobalamin-independent)
||||--|||||||||--|--|---|----|||||||||-||||||||-||----------------  1 [R] COG0622 Predicted phosphoesterase
----------------|-||-|||---|||-|--||||----|||-||-|||-|||||||||||||  1 [I] COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH)
-------------|----||------||||-|||||------|||||--|||-|||---|||||--  1 [R] COG0627 Predicted esterase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0629 Single-stranded DNA-binding protein
-----------------||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG0632 Holliday junction resolvasome, DNA-binding subunit
---|---------||||-||-|||--|---------------||||||||||-|||---|||||||  1 [C] COG0633 Ferredoxin
----------------||--||----||||||-|||||||||||||||||||||||---|||||--  1 [F] COG0634 Hypoxanthine-guanine phosphoribosyltransferase
||||||||||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [C] COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K
|||||||||||||||-|||||-----|||||-----------|||-|--|--||||---|||||--  1 [C] COG0644 Dehydrogenases (flavoproteins)
---|------------|-||-|-----||--------------------|----------|-||--  1 [R] COG0645 Predicted kinase
-----------------|||||----|||||---||||----|||||-||-----|---|||||--  1 [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain
---|--|||--||||-||--|-----|||--|||||||----|||||--|--------||||||||  1 [G] COG0647 Predicted sugar phosphatases of the HAD superfamily
--|||||||-|||---||||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7
||||-||||-|||----|||-|----|||-----||||----|||-|-||---------|||--||  1 [CP] COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit
|||-----||-|-||-|---||-----||||--|||||----||-||-||--|--|---|||-|-|  1 [R] COG0655 Multimeric flavodoxin WrbA
----------------|||||||||||||-|||||||||||||||||-||||||||||||||||-|  1 [R] COG0658 Predicted membrane metal-binding protein
|-||||-----|-||---||-------||||------|----|||||-||-|||||---|||||||  1 [R] COG0661 Predicted unusual protein kinase
----------------||||||--||||||||||||||-|--||||||||||||||||||||||--  1 [H] COG0669 Phosphopantetheine adenylyltransferase
-------------||---||||||-|----|||||||--|--|||||-||||-|||||||||||||  1 [R] COG0670 Integral membrane protein, interacts with FtsH
--------|---|||--||||---|---------|||-----||||---|-|-||---|--|--||  1 [P] COG0672 High-affinity Fe2+/Pb2+ permease
||----||--|------|------------|---|-------|||||-||-||--|---||-|---  1 [M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [M] COG0682 Prolipoprotein diacylglyceryltransferase
|||-----||---|-------|----||||-------|----|||||-||||---|---||-|---  1 [H] COG0684 Demethylmenaquinone methyltransferase
--|-||||--|||||-||||-|----|---||-|||||----||||||||||||||--||||||--  1 [E] COG0685 5,10-methylenetetrahydrofolate reductase
||||----||---||-----||||---||||-----||----|||||-|||||||||||||||-||  1 [I] COG0688 Phosphatidylserine decarboxylase
|---|||||||||||||--|||----||||-----|||----|||||-||||||||---|||||||  1 [J] COG0689 RNase PH
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0690 Preprotein translocase subunit SecE
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0691 tmRNA-binding protein
-------------|||----||||-|||||-||||||||||||||||||||||||||||||-----  1 [L] COG0692 Uracil DNA glycosylase
---|----|----||---||--||----------||||----|||||||||||---||||||||||  1 [O] COG0694 Thioredoxin-like proteins and domains
--||-----------|--||----------|---|||||||||||||-||------||||------  1 [G] COG0696 Phosphoglyceromutase
-------------|||--||-|-----||-----|-||----|||----|-----||||-------  1 [R] COG0699 Predicted GTPases (dynamin-related)
------------------|-----------|-----||----|||-|-||-----|----------  1 [S] COG0700 Uncharacterized membrane protein
--|----------||-||||||||--||||||||||||----||||||||||||||||||||||--  1 [E] COG0703 Shikimate kinase
|||||||||||||---||||-|---|||||||||||-||-|||||||-||--|--|---|||||--  1 [P] COG0704 Phosphate uptake regulator
-||||-|||||||||-||||-|--|-||||||||||||----|||||-|||||--|--||||||--  1 [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid)
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0706 Preprotein translocase subunit YidC
--|------|-|----||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase
-|-------|||----|-------------------------|||||--|||------|-|-----  1 [E] COG0709 Selenophosphate synthase
--|-------------|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0711 F0F1-type ATP synthase, subunit b
-------------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0712 F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)
--||||------|---|-||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)
|||-----||---||---|||---|-----||||-||-----|||||||||||--||||-------  1 [C] COG0716 Flavodoxins
|||||||||||||---|-||--||--|||||------|----||||||-|||||||||||||||||  1 [F] COG0717 Deoxycytidine deaminase
-----------------|||||||-|||||||||||||||||||||||||||||||||||||||||  1 [S] COG0718 Uncharacterized protein conserved in bacteria
||||||||||||----||||----------|---|-||----|||||-||||||||||||||||||  1 [H] COG0720 6-pyruvoyl-tetrahydropterin synthase
||||----||-||---||||||||||||||||||||||--||-------|---|||||||||||||  1 [J] COG0721 Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit
--||||----|||||-|-||-|----|||||-----||----------||--||||||||||||||  1 [C] COG0723 Rieske Fe-S protein
|||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||--  1 [P] COG0725 ABC-type molybdate transport system, periplasmic component
||||-|-||----------|-------||--|||||--|||||||-|-|||||---|||-||-|-|  1 [V] COG0732 Restriction endonuclease S subunits
-----------------|||||||||||||||||||||-|--||||||||||||||||||||||||  1 [L] COG0742 N6-adenine-specific methylase
----------------|||||||||-|||||----|||----|||||||||||||||||||--|--  1 [I] COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase
|||||||||||||---|-||-|----|||-----||||----|||||-||||--||||||||||--  1 [H] COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A
------------------||----------------------------||||----|||||-|---  1 [P] COG0748 Putative heme iron utilization protein
-------------|--||||||||||||||||||||||----|||||-||||||||||||||||||  1 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains
|||||||||||||---||||||||||||||||||||||----|||||-||||||||||||||||||  1 [M] COG0750 Predicted membrane-associated Zn-dependent proteases 1
----------------|||||-||-------|||-|||----||||||||||||||||||||||||  1 [J] COG0751 Glycyl-tRNA synthetase, beta subunit
----------------|||||-||-------|||-|||----||||||||||||||||||||||||  1 [J] COG0752 Glycyl-tRNA synthetase, alpha subunit
--|-----|-|-|---|-||-|----||||----|-||----|||||-||||||||||||||||||  1 [O] COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component
-------------||||---|-|||-||||||||-||-----||||||-|||||||||-|||||||  1 [F] COG0756 dUTPase
----------------||||||--|||||-|-||||||||--|||||-||||||||||||||||-|  1 [LU] COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake
----------------||||||||||-||-||||||||----|---|-|||||||||||||||||-  1 [S] COG0759 Uncharacterized conserved protein
----------------|||||||||-|||||-----||----||||||||||||||||||||||--  1 [IM] COG0761 Penicillin tolerance protein
-----------------||||-||||||||||||||||----|||||-||||---||||||-||--  1 [S] COG0762 Predicted integral membrane protein
----------------|-|||-||------------------|||||-||||||||||||||||||  1 [M] COG0763 Lipid A disaccharide synthetase
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase
|--------|------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0769 UDP-N-acetylmuramyl tripeptide synthase
|||------|------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase
|--------|------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase
----------------|-|||-||------------------|||||-||||||||||||||||||  1 [M] COG0774 UDP-3-O-acyl-N-acetylglucosamine deacetylase
--|--------------|--|||||||||-||||||||||--||||||||||-|||||||||||--  1 [F] COG0775 Nucleoside phosphorylase
----------------||||||--|||||-||||||||----|||||-||||||||||||||||||  1 [S] COG0779 Uncharacterized protein conserved in bacteria
----------|-|---||||-------------||-||----|||||-||||||||||||||||||  1 [R] COG0780 Enzyme related to GTP cyclohydrolase I
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0781 Transcription termination factor
---|--------------||||--|||----|||||||-|--|||||-|||||--|||||-|-|||  1 [P] COG0783 DNA-binding ferritin-like protein (oxidative damage protectant)
------------------|-|-----|-------|-------|||||-|||--||-||--------  1 [E] COG0786 Na+/glutamate symporter
----------------||||||--|-|||||-----------|||||-||||||||||||||||--  1 [L] COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase
|||---|||||||---|---|-||------|---|||-----|||||-||||||||||||||||||  1 [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation
----------------|-||||--||||||||||||||----||||||||||-|||||||||||--  1 [M] COG0796 Glutamate racemase
----------------||||-|||||||||-|||||||----|||||-||||||||||||||||||  1 [S] COG0799 Uncharacterized homolog of plant Iojap protein
----------------||||||||||||||||||||||-|--|||||-||||||||||||||||||  1 [R] COG0802 Predicted ATPase or kinase
--------------|---||-|----|||-----|-|||----|||---||----|||-||||---  1 [E] COG0804 Urea amidohydrolase (urease) alpha subunit
--||||--|-|||---|-||-|----||||----||||----|||||-||||||||||||||||||  1 [U] COG0805 Sec-independent protein secretion pathway component TatC
----------------||||||--||||||||||||||----||||||||||||||||||||||||  1 [J] COG0806 RimM protein, required for 16S rRNA processing
----------------||||||---|----||||||||----||||||||||||||||||||||||  1 [J] COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0812 UDP-N-acetylmuramate dehydrogenase
----------------||||-|||||||||------------|||||-||||-|||||||||||||  1 [M] COG0815 Apolipoprotein N-acyltransferase
----------------||||||||--|||||||-||||||||||||||||||||||||||||||||  1 [L] COG0816 Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis)
-----------------||||||||-||||------------|||||-||||||||||||||||||  1 [L] COG0817 Holliday junction resolvasome, endonuclease subunit
-----------------|||-|--------||||||||----|||||-|||||||||||||||---  1 [M] COG0818 Diacylglycerol kinase
----------------|||||||||-|||||-----||----||||||||||||||||||||||--  1 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis
--||----|----|||||-||-||||||||||||||||||||||||||||||-|||||||||||||  1 [C] COG0822 NifU homolog involved in Fe-S cluster formation
----------------|-||||||--|||-||||||||----|||||-||||||||||||||||--  1 [I] COG0825 Acetyl-CoA carboxylase alpha subunit
----------------|-||--||||----|||||||||-||||||||||||||||||||||||||  1 [J] COG0828 Ribosomal protein S21
--------------|---||-|----|-------|--||----||----||----|||-||||---  1 [O] COG0829 Urease accessory protein UreH
--------------|---||-|----|||-----|--||----|||---||----|||-||||---  1 [O] COG0830 Urease accessory protein UreF
--------------|---||-|----|||-----|-|||----|||---||----|||-||||---  1 [E] COG0831 Urea amidohydrolase (urease) gamma subunit
--------------|---||-|----|||-----|-|||----|||---||----|||--|||---  1 [E] COG0832 Urea amidohydrolase (urease) beta subunit
------------------||----------------------|||||--|--||||||-|||||--  1 [G] COG0837 Glucokinase
--||||--|--||---|-||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J)
---------|------||--||--||----||||||||----||||||||||||||||||||||||  1 [D] COG0849 Actin-like ATPase involved in cell division
----------------||||||--------|----|||----||||||||-|||||||-||||---  1 [D] COG0850 Septum formation inhibitor
------------------||||--------------------||||||||--||||||-||||---  1 [D] COG0851 Septum formation topological specificity factor
--|||||||-|||---||||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit
----------------||||-|----|||||---||||----|||||--|--||||||||--||--  1 [H] COG0853 Aspartate 1-decarboxylase
----------------|-||----------------------|||||-||--||||||||||||--  1 [H] COG0854 Pyridoxal phosphate biosynthesis protein
--|---------------||-|-----||||------|----|||||-||--||||||||||||--  1 [P] COG0855 Polyphosphate kinase
---|----|---------||-|-----||-------------||||||||||-||-|||-------  1 [R] COG0857 BioD-like N-terminal domain of phosphotransacetylase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0858 Ribosome-binding factor A
--||||--|-|||---|-||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H)
||||--||---------|||-|----|-------||||----------||---------|||--||  1 [P] COG1006 Multisubunit Na+/H+ antiporter, MnhC subunit
--||||--|-|||---|-||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N)
--||||----------|-||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M)
||||||--||||------|||------||-|----|----------|--|-----|---||||---  1 [H] COG1010 Precorrin-3B methylase
-------------||-|----|----|-------|-||----|||||-||--|--|--|-|-----  1 [C] COG1017 Hemoglobin-like flavoprotein
---------------------------||-------|-----|||||-||-----------|----  1 [Q] COG1021 Peptide arylation enzymes
---|----|-|-|||||-|||---||||||---------------|--||||--------------  1 [I] COG1022 Long-chain acyl-CoA synthetases (AMP-forming)
-------------|||------||------------------|||||-||----------------  1 [O] COG1025 Secreted/periplasmic Zn-dependent peptidases, insulinase-like
----||-----------|-|------|---|-----||----|||||-||||-||-||||-|----  1 [E] COG1027 Aspartate ammonia-lyase
--|-|||||-|-|---|-----------------|-||-----------|-----|----|-|---  1 [O] COG1030 Membrane-bound serine protease (ClpP class)
-|||--||||-------|------||-----------|-----------|--------|-------  1 [R] COG1033 Predicted exporters of the RND superfamily
----------------||||-|-----||-|-----------||||||-|--||||||||||||||  1 [C] COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)
----------------||||||--||-||-||||||||----|||||-||||||||||||||||-|  1 [R] COG1040 Predicted amidophosphoribosyltransferases
----------------|-|||-||------------------|||||-||||||||||||||||||  1 [M] COG1043 Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase
----------------|-|||-||------------------|||||-||||||||||||||||||  1 [M] COG1044 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase
------------------||----------------------|||||-||-|||||||||------  1 [C] COG1049 Aconitase B
------------------||-|||--|----||||||-----||||||||--|--|---|||||||  1 [R] COG1054 Predicted sulfurtransferase
----|||||-|||----||||-||---|||----||||----||||--||---|||--||--|---  1 [P] COG1055 Na+/H+ antiporter NhaD and related arsenite permeases
-----------|-||---||------||||-------|----|||||--||--|||---|||||--  1 [C] COG1062 Zn-dependent alcohol dehydrogenases, class III
----------------|||||||||-|||-|||-||||----|||||-||||||||||||||||||  1 [O] COG1066 Predicted ATP-dependent serine protease
||||||||||-------|------|-----|-----||----|||||-||||--------------  1 [O] COG1067 Predicted ATP-dependent protease
--------------------|-||||-||-||||||||----||||||||||||||||||||||||  1 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)
|---||--||------||-||-||||----|----|||----|||||-|||||--||||----|||  1 [D] COG1077 Actin-like ATPase involved in cell morphogenesis
---|--|||-|-|----|-|-|--||----||||-||-||||-------|-----|---||||---  1 [R] COG1079 Uncharacterized ABC-type transport system, permease component
-|---------------|--|---|-|---|--||-||----------||-||||||||-||||||  1 [MG] COG1086 Predicted nucleoside-diphosphate sugar epimerases
|------------||-|-||||----|---||-|-|||--|||||||-||||-|||||||||||--  1 [M] COG1087 UDP-glucose 4-epimerase
|-|--||||--||-|---||||----|||||||---||----|||||--|||||||---||-||--  1 [M] COG1088 dTDP-D-glucose 4,6-dehydratase
|-|-----|-------|-||-------||-|-----------|||-|-||--|---||-|-|||--  1 [M] COG1089 GDP-D-mannose dehydratase
----||------------||------||||----||||----|||||--||||-------------  1 [R] COG1090 Predicted nucleoside-diphosphate sugar epimerase
--------------------|-----|-----||--------------||-----|---||||-||  1 [R] COG1101 ABC-type uncharacterized transport system, ATPase component
-----------------|--||---||||-||||||||--|||||||-||||---|----------  1 [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)
||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||--  1 [P] COG1117 ABC-type phosphate transport system, ATPase component
------------------||-------||--------|----|||||-||--||||||||||||--  1 [P] COG1118 ABC-type sulfate/molybdate transport systems, ATPase component
--------|----------|||-----||-|||||||-----|||||--|------||-||||---  1 [E] COG1125 ABC-type proline/glycine betaine transport systems, ATPase components
-----------------|--|---|||----|----||-|--|||||-||||---|---|||||--  1 [G] COG1129 ABC-type sugar transport system, ATPase component
----------------||||||||||----------------|||||-||||||||||||||||||  1 [R] COG1137 ABC-type (unclassified) transport system, ATPase component
--|-----|-|-|--------|--------------------|||||-|||||------|||||||  1 [O] COG1138 Cytochrome c biogenesis factor
----------|-|-------------|||-----|-|-----|||-|--|-----|-----|----  1 [C] COG1140 Nitrate reductase beta subunit
|||||||||-|||---||||-|-----||-------------||||||-|--||||||||||||||  1 [C] COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)
----------------|||||||||-||||||---|||----||||||||||||||||||||||--  1 [HI] COG1154 Deoxyxylulose-5-phosphate synthase
----------------||--|||||||||||---||||----||||||||||||||||||||||||  1 [K] COG1158 Transcription termination factor
----------------||||||--||||||||||||||||||||||||||||||||||||||||||  1 [R] COG1159 GTPase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [R] COG1160 Predicted GTPases
--|-------------|||||----||||||||||||||||||||||-||||||||------|---  1 [R] COG1162 Predicted GTPases
------------------||-|--------------------|||||-||-||||-|||-------  1 [E] COG1166 Arginine decarboxylase (spermidine biosynthesis)
---|--------------||------||||-|--|||-----|||||-||||---------|----  1 [HQ] COG1169 Isochorismate synthase
-----------------|--|-----|--|-|----||----|||||-||||---|---|||||--  1 [G] COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components
--|||||||-|||---||||||||-||||||||||||||||||||||-||||---||-|||||---  1 [EP] COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components
-------------||-----|---------|---|-||----|||||-|||||||||||-------  1 [H] COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
|||-|||||||||---||--|------||-||||||------|||||-||||---|----------  1 [O] COG1180 Pyruvate-formate lyase-activating enzyme
-------------||-||||||||||||||||||||||----||||||||||||||||||||||||  1 [J] COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)
-----------------|--|-----|---||||||||----|||||-||||-|||||||||||--  1 [J] COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
--|-------||-|||||||||||--|||||||||||||||||||||||||||||||||||-----  1 [J] COG1190 Lysyl-tRNA synthetase (class II)
----------------||||--|||--||-|---||||----|||||-||-----||||-------  1 [K] COG1191 DNA-directed RNA polymerase specialized sigma subunit
|--|------|-|-|------||||-||||||||||||----||||||||||||||||||||||--  1 [L] COG1194 A/G-specific DNA glycosylase
----------|-------|||||-|-||||||||||||----|||||-|||||------|||||||  1 [L] COG1195 Recombinational DNA repair ATPase (RecF pathway)
-||||||||----|||||||||--||||||||||||||||||-------|--|||----|||||--  1 [D] COG1196 Chromosome segregation ATPases
-----------------|||||||||||||||||||||----||||||||||||||||||||||||  1 [LK] COG1197 Transcription-repair coupling factor (superfamily II helicase)
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1 [L] COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase
----------------||||||--||||||||||||||----|||||-||||||||||||||||||  1 [LK] COG1200 RecG-like helicase
|||||||||||||------|------|||-------------|||----|-----|---|||||--  1 [R] COG1201 Lhr-like helicases
----------------||||||----||||||||||||----||||||||||||||||||||||||  1 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)
|||||||||||||||||-||-|----|||||-----||-------||--|--||||--||||||--  1 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)
|-|||||||--||----|||-|----|||||||---||----|||||--|--||||---||-||--  1 [M] COG1209 dTDP-glucose pyrophosphorylase
|||----|---|----|--||----|||||||||||||--|||||||-||||||||||||||||--  1 [M] COG1210 UDP-glucose pyrophosphorylase
------|---------|||||||||-|||||--|||||--||||||||||||||||||||||||--  1 [I] COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase
----------------|---|-||------------------|||||-||||||||||||||||||  1 [M] COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase
|-----|||---|---|---|----------------------------|--------|----|--  1 [M] COG1213 Predicted sugar nucleotidyltransferases
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone
|-|--||||---|-----||-|----|||||-----------|---|--||-|--|---||-||--  1 [R] COG1216 Predicted glycosyltransferases
------------------||||----||||||||||||----||||||||||||||||||||||||  1 [T] COG1217 Predicted membrane GTPase involved in stress response
-------------||-|-||--||--||||------------|||||||||||-----||||||||  1 [P] COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase
-------------|--||||||||||||||||||||||----||||||||||||||||||||||||  1 [O] COG1219 ATP-dependent protease Clp, ATPase subunit
----------------||-------|--------||||----|||||||||||--|||||||||||  1 [O] COG1220 ATP-dependent protease HslVU (ClpYQ), ATPase subunit
--||||----|||||-||||-|----|||||---|-||----|||||-||||||||||||||||-|  1 [O] COG1225 Peroxiredoxin
|--||||-|--|-|---|--||-----||-|-|-|-||-------||-||-----|---|||||--  1 [Q] COG1228 Imidazolonepropionase and related amidohydrolases
------------------||-|----|||-------|------------|-----|------||--  1 [E] COG1231 Monoamine oxidase
-||||||-|-||||||--||-|--------------------------||-----|---||-||--  1 [J] COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing
||||||--||--------||-|----|||--------------------|-----|----------  1 [H] COG1239 Mg-chelatase subunit ChlI
||||||---|--------||------|||--------------------|-----|----------  1 [H] COG1240 Mg-chelatase subunit ChlD
--||------------|----|-----|||------||----||||||||-|-|||----------  1 [E] COG1246 N-acetylglutamate synthase and related acetyltransferases
--|-------|-|-----||-|----|---||-|||||----|||-|-||-----|---|||||--  1 [M] COG1247 Sortase and related acyltransferases
-||-|||||-|||----|-|-|---|--|-||||||||----|||||-||-|---|----|-|---  1 [C] COG1254 Acylphosphatases
----------------||------||----|----|||----||||||||-----|||||||||--  1 [N] COG1256 Flagellar hook-associated protein
----------------||------------------------||||||||-----|||||||||--  1 [NO] COG1261 Flagellar basal body P-ring biosynthesis protein
--------------------|----||---||||||||-|||||||||||-|---|-------|--  1 [G] COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific
--------------------|----||---||||||||||||||||||||-|---|-------|--  1 [G] COG1264 Phosphotransferase system IIB components
|||---||-||-|---|---|-----------|--|||----|||||-||||-||||||-----||  1 [I] COG1267 Phosphatidylglycerophosphatase A and related proteins
|||||||||||||-----||||-----||-|----|-|--------|-||-----|---||||---  1 [H] COG1270 Cobalamin biosynthesis protein CobD/CbiB
--||||--|-------|-||--||--|||--|--||||----|||||-||||---|--||||||||  1 [C] COG1271 Cytochrome bd-type quinol oxidase, subunit 1
-------------|||----||--|||||-||||||||----|||||-||--|||----|||||--  1 [R] COG1272 Predicted membrane protein, hemolysin III homolog
--------|------------------||-------||-----------|---------||-|---  1 [S] COG1273 Uncharacterized conserved protein
--------------------|-----|||-|---|-||----|||||-||-|---|||-|-|---|  1 [R] COG1279 Lysine efflux permease
----------------||||||--------||||||||-|--|||||-||||||||---|||||--  1 [O] COG1281 Disulfide bond chaperones of the HSP33 family
------------------||-------|||------------|||||-||||-|||---|||||||  1 [C] COG1282 NAD/NADP transhydrogenase beta subunit
------------------------||-----|||||||----|||||-||||||||||||||||||  1 [R] COG1286 Uncharacterized membrane protein, required for colicin V production
---|||----||||--|-||-|----||||------||----------||--||||||||||||||  1 [C] COG1290 Cytochrome b subunit of the bc complex
--||------------|-||--||--|||--|--||||----|||||-||||---|--||||||||  1 [C] COG1294 Cytochrome bd-type quinol oxidase, subunit 2
--|-----|-----------||----|----|-|||||----|||||-||||-|||||-||||---  1 [E] COG1296 Predicted branched-chain amino acid permease (azaleucine resistance)
---|--|------|-------------||--------------------||-||||--|----|--  1 [S] COG1297 Predicted membrane protein
----------------||----||||----|----|||----||||||||-----|||||||||--  1 [NU] COG1298 Flagellar biosynthesis pathway, component FlhA
--------------------||---||---||||||||-||||||||-|||----|----------  1 [G] COG1299 Phosphotransferase system, fructose-specific IIC component
|||---||||--|-----||-------||-|---|-||-----------|------------||--  1 [S] COG1300 Uncharacterized membrane protein
-----------------|--||----|||-||||||||||||-------|----------------  1 [S] COG1307 Uncharacterized protein conserved in bacteria
----------------|-|||||||||||||||||||||-|-||||||||||||||||||||||||  1 [U] COG1314 Preprotein translocase subunit SecG
----------|||--------|--||-||-------||----|||----|-----|---||-|---  1 [C] COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs
||||--||---------|---|----|-------||||----------||---------|||--||  1 [P] COG1320 Multisubunit Na+/H+ antiporter, MnhG subunit
----------------------||-------|||-----|--|||||-||||||||---|||||||  1 [S] COG1322 Uncharacterized protein conserved in bacteria
-----------------||-||||--||||||||||||----|||||-||||||||---|||||--  1 [K] COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains
|||---||-|-------|--|---------||||||------|||||-||||---|----------  1 [F] COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase
----------------------||-|-||-------------|||||||||||||-----------  1 [L] COG1330 Exonuclease V gamma subunit
----------------||------------|-----||----------||------|||-------  1 [N] COG1334 Uncharacterized flagellar protein FlaG
----------------||----||||----|----|||----||||||||-----|||||||||--  1 [NU] COG1338 Flagellar biosynthesis pathway, component FliP
----------------||------||----|----|||----|||||-||-----||||-------  1 [N] COG1345 Flagellar capping protein
----------------------||---------------------|--||||-||-----------  1 [C] COG1347 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD
-||||||||-------||||||--|-||||||||||||||||-------|--||||---|||||--  1 [S] COG1354 Uncharacterized conserved protein
-------------||--|--|----||||||------------------|----------------  1 [E] COG1362 Aspartyl aminopeptidase
|||-----||---||-||||-|----||||||--||||-----------|---|||---|||||--  1 [E] COG1364 N-acetylglutamate synthase (N-acetylornithine aminotransferase)
----------------||----||||----|----|||----||||||||-----|||||||||--  1 [NU] COG1377 Flagellar biosynthesis pathway, component FlhB
------------------|||||||-||||||||||||||--|||||-||||||||---|||||||  1 [L] COG1381 Recombinational DNA repair protein (RecF pathway)
--|-|||||--------|||||--|-||||||||||||||||-------|--||||---|||||--  1 [K] COG1386 Predicted transcriptional regulator containing the HTH domain
----------------|----|||-||||-||--||||-------|--||||--------------  1 [M] COG1388 FOG: LysM repeat
----------------|---------||||------------|||||-||||-|||---|||||--  1 [OT] COG1391 Glutamine synthetase adenylyltransferase
|||---|||--|-----|---|||------|---|||-----------||||---|---||-|---  1 [P] COG1392 Phosphate transport regulator (distant homolog of PhoU)
-------------||---||-----------------------------|-----|--------||  1 [I] COG1398 Fatty-acid desaturase
----------------||||-|----||||||||||||----|||||-||||||||----------  1 [R] COG1399 Predicted metal-binding, possibly nucleic acid-binding protein
|-|---|||||-|||-|-||--||--||||||--|||-----|||||-||||---|---|||||--  1 [R] COG1409 Predicted phosphohydrolases
-----------------|||-|----|||||------|----|||||-|||-|--|---|||||--  1 [E] COG1410 Methionine synthase I, cobalamin-binding domain
|-||---------|||--||--||||--------|-||----||-----|------------|---  1 [C] COG1413 FOG: HEAT repeat
----------------||------||----|----|||----------||-----||||-------  1 [N] COG1419 Flagellar GTP-binding protein
-----------------|-|--||||-----|||||||----|||||-|||||--|--------||  1 [S] COG1426 Uncharacterized protein conserved in bacteria
||||--||||------|-||-|--|-|---------------------||----|-||||||||--  1 [S] COG1432 Uncharacterized conserved protein
--------------------||---||---||||||||-||||||||-||||---|----------  1 [G] COG1445 Phosphotransferase system fructose-specific component IIB
||||--|||-------|---||----|---|-------||--|||||-||--||||||||||||-|  1 [R] COG1451 Predicted metal-dependent hydrolase
----------------|-------||----------------|||||-||||||||||||||||||  1 [M] COG1452 Organic solvent tolerance protein OstA
----------------|-||-|--------------------|||||--|---|||-------|--  1 [M] COG1462 Uncharacterized protein involved in formation of curli polymers
----------------||||-|||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG1466 DNA polymerase III, delta subunit
||||||||||--|----|----------------|-||-----------|--||||----------  1 [S] COG1469 Uncharacterized conserved protein
||||---||----------|-|--------||||||||-----------|-------------|--  1 [K] COG1476 Predicted transcriptional regulators
--|-------------||--|||||-----||||-|------|||||-||||||||----||||--  1 [H] COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis
|---||--|-|||---||||----------|------|----|||||-||||-------|||-|--  1 [R] COG1489 DNA-binding protein, stimulates sugar fermentation
-------------||-||--||----|||-||||||||----|||||-||||-|||----------  1 [J] COG1490 D-Tyr-tRNAtyr deacylase
||||||--||-|------||||-----||-|----|-|--------|-||-----|---|||||--  1 [H] COG1492 Cobyric acid synthase
---|||||--|||||---|-||------------|-||-----------|--|------|---|-|  1 [E] COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases
----------------|-----||||----|----|||----|||||-||--||||||||||||--  1 [K] COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
----------------|-||----------------------|||----|-----|----------  1 [P] COG1513 Cyanate lyase
|||-|||||||||---||-|-|----|---|---|-||----|||||--|-----|---|||||--  1 [J] COG1514 2'-5' RNA ligase
----------------||------||----|----|||----|||||-||-----||||-------  1 [NUO] COG1516 Flagellin-specific chaperone FliS
----------------|---|-||------------------|||||-||||||||||||||||||  1 [M] COG1519 3-deoxy-D-manno-octulosonic-acid transferase
||||--|||--------|---|---|-|||------|-----|||||-||--|--|-------|||  1 [S] COG1520 FOG: WD40-like repeat
----------------||||||--||-||||----|||-|---------|--|||||||----|--  1 [K] COG1521 Putative transcriptional regulator, homolog of Bvg accessory factor
--|--------|-----||-||||--|||-|-||--||-|--|||||-||||---|---||-|---  1 [G] COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases
----|||||--|-|||-|-|------|---|----|-|-----------|--|-----|-|-||--  1 [R] COG1524 Uncharacterized proteins of the AP superfamily
||-|--||-|---||-|--|------|-------|-|--|||-------|||-||---|||||---  1 [L] COG1525 Micrococcal nuclease (thermonuclease) homologs
|||-||--|-||--------------|||-----||||----|||||-||||---|--||||||--  1 [C] COG1526 Uncharacterized protein required for formate dehydrogenase activity
-||-|-|||||||----||-|------||-|-----||-----------|-----|---|||||-|  1 [L] COG1533 DNA repair photolyase
||||--||||-||-------|---------||||||||----|||||-||||||||----------  1 [J] COG1534 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein
----------------||----||||----|----|||----||||||||-----|||||||||--  1 [N] COG1536 Flagellar motor switch protein
----------------||||||-|-|||||||||||||----|||||-|||||--|---|||||||  1 [J] COG1544 Ribosome-associated protein Y (PSrp-1)
-----------------|------||----|-----||----|||||||||||---|||-------  1 [T] COG1551 Carbon storage regulator (could also regulate swarming and quorum sensing)
|||------|-------|------------------------||||||||||--------------  1 [P] COG1553 Uncharacterized conserved protein involved in intracellular sulfur reduction
--|--------------|||||----|||-||||||||----|||||-||||||||--|-------  1 [L] COG1555 DNA uptake protein and related DNA-binding proteins
----------------||------||----|----|||----||||||||-----|||||||||--  1 [N] COG1558 Flagellar basal body rod protein
----------------|---||--||||||||||-|||----|||||-||||||||||||||||||  1 [R] COG1559 Predicted periplasmic solute-binding protein
----------------||--|----|----|----|||----|||||-||||||||---|||||--  1 [S] COG1561 Uncharacterized stress-induced protein
-----------------|-|||||--||||||||||||----|||||-||||||||||||||||||  1 [L] COG1570 Exonuclease VII, large subunit
-----------------|--||--------||||||||||--|||||-||||||||||||||||--  1 [S] COG1576 Uncharacterized conserved protein
||-|--||-||||----|||||----|||||-----------|||||-||-||------|||||--  1 [OU] COG1585 Membrane protein implicated in regulation of membrane protease activity
||||||--||||-||-|-||||||--|||||---||||----|||||-||-||||||||||||---  1 [H] COG1587 Uroporphyrinogen-III synthase
------------------||-|--||||||||||||||----|||||-||||||||---|||||||  1 [M] COG1589 Cell division septal protein
----------------||||----------------------|||-|-||-|||||--||||||--  1 [M] COG1596 Periplasmic protein involved in polysaccharide export
----|--------||--|||-|----|||-||||||||----|||||--|---------||-||--  1 [IR] COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
|-|-----|---------||-|--------|-|-||||----|||||-||-----|---|||||--  1 [C] COG1600 Uncharacterized Fe-S protein
-------------|---|--------|||-|----|||----------||--||||--|||||---  1 [S] COG1610 Uncharacterized conserved protein
---|--------|||-|-||-|----||||----||||-----------|--|--|---|||||||  1 [O] COG1612 Uncharacterized protein required for cytochrome oxidase assembly
----||------------||||--|-----||-|-|||-|--|||-|-||---|||--------||  1 [V] COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF
---|----||-|---------|---|--------|-||----|||-|-||||-||||||--|----  1 [C] COG1620 L-lactate permease
-------------|||---|----||----------------|||-|--|-----|----------  1 [G] COG1626 Neutral trehalase
----------|-----|-||||||-||||--|||--------|||||-||||---|----------  1 [G] COG1640 4-alpha-glucanotransferase
||||||--|||-|||-|---|------||-|---||||----||||||||--|||----|||||--  1 [H] COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)
--||---||------------|--------||||||||----|||||-|||||-------------  1 [K] COG1654 Biotin operon repressor
--------------------||----||||||||||||----|||||-||||||||----------  1 [R] COG1660 Predicted P-loop-containing kinase
----------------|---|-||------------------|||||-||||||||||||||||||  1 [M] COG1663 Tetraacyldisaccharide-1-P 4'-kinase
----------------------||||----|-----|--------|--||--|--||||----|--  1 [M] COG1664 Integral membrane protein CcmA involved in cell shape determination
-------------------|-------||-------||----|||||-||||---|--|-------  1 [S] COG1666 Uncharacterized protein conserved in bacteria
------------------------||----|---||||----|||||-||---------|||||--  1 [S] COG1671 Uncharacterized protein conserved in bacteria
-------------------|-||||||||||||||||||---|||||-||||||||||||||||||  1 [D] COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins
----------------||------||----|----|||----||||||||-----|||||||||--  1 [NU] COG1677 Flagellar hook-basal body protein
---------------------|||--||||------------|||||-||||||||---|||||||  1 [K] COG1678 Putative transcriptional regulator
|||---|||||-|------------------------------------|---------||-|---  1 [S] COG1679 Uncharacterized conserved protein
----------------||------||----|----|||----||||||||-----|||||||||--  1 [NU] COG1684 Flagellar biosynthesis pathway, component FliR
-------------||----||---|-----|||||||------------|---||-|-|-|-----  1 [M] COG1696 Predicted membrane protein involved in D-alanine export
---------||-|---||||-|----||||-|||||||----|||||-||-|||||---|||||--  1 [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase
-----------------|-------------||-|||-----|||||-||-----|-----|----  1 [NU] COG1705 Muramidase (flagellum-specific)
----------------||-------|----------------||||||||-----|||||||||--  1 [N] COG1706 Flagellar basal-body P-ring protein
|||-----|||------|-------------------------------|-----|----------  1 [R] COG1712 Predicted dinucleotide-utilizing enzyme
||||||||||||||||-----|-----------------------|---|----------------  1 [TD] COG1718 Serine/threonine protein kinase involved in cell cycle control
||||--|||||||----|------------------------|||||-||||-||-------||--  1 [S] COG1720 Uncharacterized conserved protein
-----------------|-|||----||||||||||||----|||||-||||||||||||||||||  1 [L] COG1722 Exonuclease VII small subunit
----------------------||---------------------|--||||-||-----------  1 [C] COG1726 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA
----------------|-------------------------|||||-||--||||---|||||||  1 [S] COG1729 Uncharacterized protein conserved in bacteria
---|----|----------|||-----||-|||||||-----|||-|--|-----|||-||||---  1 [M] COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
--||----|-|-|----|--||||-||-------|-|-----|||||-||||-||----||||---  1 [S] COG1738 Uncharacterized conserved protein
--||---------||--|--||---||---||||||||||--|||-|-||||-|||||||||----  1 [S] COG1739 Uncharacterized conserved protein
--|---------------|--------||-----|-||----|||-|--|-----|---||-||--  1 [S] COG1742 Uncharacterized conserved protein
---|--|||-|-|----|-|-|--||----||||-|||||||-------|-----|---||||---  1 [R] COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein
----------------|-------||----|----|------||||||||-----|||||||||--  1 [N] COG1749 Flagellar hook protein FlgE
||||||||||||||||||||-|--||||||||||||||----|||||-||||||||||||||||||  1 [K] COG1758 DNA-directed RNA polymerase, subunit K/omega
--------------------|-|||||---||||||||-||||||||-||||-|||---|||||--  1 [GT] COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)
----------------||------||----|----|||----||||||||-----|||||||||--  1 [NU] COG1766 Flagellar biosynthesis/type III secretory pathway lipoprotein
|||---||||-||-------|-----------|---------|||-|-|||---------------  1 [H] COG1767 Triphosphoribosyl-dephospho-CoA synthetase
-------------------|------||||---|--------|||||-||--|------|||||||  1 [E] COG1770 Protease II
--|-------------|---|---------------------|||||-|||||||||||-------  1 [R] COG1778 Low specificity phosphatase (HAD superfamily)
--||---|-----||--|-|-|----|-------|-||----||||---|--|--|-----|----  1 [P] COG1785 Alkaline phosphatase
|||---|||||-|------------------------------------|---------||-|---  1 [S] COG1786 Uncharacterized conserved protein
-------------||-|--|----------------|------------|--|-------------  1 [S] COG1791 Uncharacterized conserved protein, contains double-stranded beta-helix domain
----------------|--||-||||----||-|||||----|||||-|||||--||||----|||  1 [M] COG1792 Cell shape-determining protein
|||||||||||||||||----------||-------||----------|||--||---|||-||--  1 [L] COG1793 ATP-dependent DNA ligase
||||||--||||------||||-----||-|----|-|--------|--|-----|---||||---  1 [H] COG1797 Cobyrinic acid a,c-diamide synthase
------------------||--||---------------------|--||||-||-------|---  1 [C] COG1805 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB
---------------------|------------||||----|||||-||--||||---|||||||  1 [S] COG1806 Uncharacterized protein conserved in bacteria
||--|||||||||||--|---||---|----|-----------------|------------||--  1 [S] COG1814 Uncharacterized membrane protein
----------------||------||----|----|||----||||||||-----|||||||||--  1 [N] COG1815 Flagellar basal body protein
-------------||----|----|--|-|||----------|||-|-||-----|---||-||--  1 [F] COG1816 Adenosine deaminase
|||------|---|----|--|-----||||-----|------||||-||------------|---  1 [GC] COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
-----------|-----|-|||---||||-||||||||-|--|||||-|||||------|||||--  1 [G] COG1820 N-acetylglucosamine-6-phosphate deacetylase
----------------||||-|||||||||----||||----||||||||||||||||||||||||  1 [J] COG1825 Ribosomal protein L25 (general stress protein Ctc)
--|---------|-----||-------||-|-----||-----------|----------|-|---  1 [E] COG1834 N-Dimethylarginine dimethylaminohydrolase
|||---|||||-----||------------|------|----|||||-||--||||-----||---  1 [C] COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain
||||||||||||||||||--||--||||||||||||||----||||||||||||||----||||||  1 [J] COG1841 Ribosomal protein L30/L7E
--|-------------|-||-|----|||-|----|||----|||||-||------------||--  1 [KT] COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
----------------||------||----|----|||----||||||||-----|||||||||--  1 [N] COG1843 Flagellar hook capping protein
--|-|||||||-|||-----||--------------------|||----|---------|------  1 [J] COG1859 RNA:NAD 2'-phosphotransferase
----------------||--|-||-|||||||||||||----||||||||||||||||||||||||  1 [U] COG1862 Preprotein translocase subunit YajC
||||--||---------|---|----|-------||||----------||---------|||--||  1 [P] COG1863 Multisubunit Na+/H+ antiporter, MnhE subunit
--|----------||----||----|--------------------|--|-----||||----|--  1 [F] COG1864 DNA/RNA endonuclease G, NUC1
------------||------||------------|-||----|||||-||||------|||||---  1 [C] COG1866 Phosphoenolpyruvate carboxykinase (ATP)
----------------||------||----|----|||----||||||||-----||||||||---  1 [N] COG1868 Flagellar motor switch protein
--||--|||--------|-------|----|-----||----------||-----|---||--|--  1 [NT] COG1871 Chemotaxis protein; stimulates methylation of MCP proteins
-----------------|----||--||||------||----------||--|--|----------  1 [T] COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH
||||||-||-||-----|||------|||-----|--|-----------|||---|---||-|---  1 [R] COG1878 Predicted metal-dependent hydrolase
--|--------------|--|---|-|--|||----||----|||||-||||---|---|||||--  1 [G] COG1879 ABC-type sugar transport system, periplasmic component
|-----|------------------------|--|||------------|--|-------------  1 [M] COG1887 Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC
|-------------|-||||-|-----||-------------||||||-|--||||---|||||||  1 [C] COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit
---|--|||||||||------|------------||------|||||-||-|----||||||||--  1 [R] COG1896 Predicted hydrolases of HD superfamily
|-|--||||--||-----||||----|||||||||-||----|---|--|-|||||--||||||--  1 [M] COG1898 dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes
|||-||--||||------|||---------|----|----------|--|-----|---|-|----  1 [H] COG1903 Cobalamin biosynthesis protein CbiD
|-------------|-||||-|-----||-------------||||||-|--||||---|||||||  1 [C] COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit
|||----|||-------||--|--------||--||------|||||-||--|--|-||----|--  1 [P] COG1918 Fe2+ transport system protein A
||--|----|------|-------------------------|||||--|||----|||||-|---  1 [E] COG1921 Selenocysteine synthase [seryl-tRNASer selenium transferase]
-|--------------||------------|---||||----|||||-||||||||----||||--  1 [R] COG1923 Uncharacterized host factor I protein
------------------|-------|||-||||||||----|||||-||||-||-----------  1 [G] COG1929 Glycerate kinase
--|----------||----|------||||-|---|||----||||||||||||||--||||||--  1 [HE] COG1932 Phosphoserine aminotransferase
----------------|-||----------------------|||||-||||||||||||||||--  1 [S] COG1934 Uncharacterized protein conserved in bacteria
------------------||-|----||||||--||||----|||-|--|-----|--|||-----  1 [S] COG1937 Uncharacterized protein conserved in bacteria
--||||-----|-----|-|||------|-|--|---|----|||||-|||--|||||----||--  1 [L] COG1943 Transposase and inactivated derivatives
||||-----|-----------------||-------------|||||--|||-------||-|---  1 [S] COG1944 Uncharacterized conserved protein
----------------|||||||-|-|||||---|||||---||||||||||||||||||||||--  1 [I] COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase
-------------||-----------||||------------||||||||||||||----------  1 [A] COG1949 Oligoribonuclease (3'->5' exoribonuclease)
|||---|||||-----||------------|------|----|||||-||--||||-----||---  1 [C] COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain
-|----------------------------------------||||||||||||||---|||||||  1 [U] COG1952 Preprotein translocase subunit SecB
---|||-------|---|------------||||||||----|||||-||-||||-------||--  1 [T] COG1956 GAF domain-containing protein
-----------|-||----|-|----|||-----|--|----|||-|--|-|---|--||||||--  1 [F] COG1957 Inosine-uridine nucleoside N-ribohydrolase
-----||---|-------||-|----|||-|-||||||----|||||-||--|--|---|||||--  1 [L] COG1961 Site-specific recombinases, DNA invertase Pin homologs
-------------|||--------------------------||||||||||-|||--------||  1 [P] COG1965 Protein implicated in iron transport, frataxin homolog
--|----|--|-|---|---|-----|||-||----||----|||||-||||-||||||-------  1 [T] COG1966 Carbon starvation protein, predicted membrane protein
|--------|||----||||||---||||||||||-||----||||||||--||||--||||||--  1 [V] COG1968 Uncharacterized bacitracin resistance protein
--|---------------|-||----||||-||||||-----|||||-|||||--|---|||||--  1 [M] COG1970 Large-conductance mechanosensitive channel
|-|-----------------|-----|---|-----||----|||||--|--|||---|-------  1 [S] COG1971 Predicted membrane protein
-----------------|||-|----||||||--||||----|||||-|||||--|---|||||--  1 [KT] COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases)
--||||-||-||----|-||-|-----||-----||||----|||||-||||---|||||||||--  1 [H] COG1977 Molybdopterin converting factor, small subunit
------------------||-----------------------------|--||||||||||||||  1 [S] COG1981 Predicted membrane protein
||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG1985 Pyrimidine reductase, riboflavin biosynthesis
----------------||------||----|----|||----||||||||-----|||||||||--  1 [NU] COG1987 Flagellar biosynthesis pathway, component FliQ
|||---||||--|-----------------|---||||----|||||--|-|--------------  1 [R] COG1988 Predicted membrane-bound metal-dependent hydrolases
||||--||||------||||-|----|||-||||||||----|||||-||||||||--|---||--  1 [NOU] COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
---|------|-|||-|----|--------------||----------||--||||--||||||||  1 [R] COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems
---------------------|--|-|||||---|||||||||||||--|||||||----|--|||  1 [S] COG2001 Uncharacterized protein conserved in bacteria
--|-------------|||||---------||||||||----|||||-||||||||---||||--|  1 [L] COG2003 DNA repair proteins
|-|-----||||------------------------------|||||--|||---|--|||-||--  1 [R] COG2005 N-terminal domain of molybdenum-binding protein
---|||--|-|-|||------|||---|||----|-||----|||||-||--||||||||||||||  1 [C] COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit
|-||||-|||-||----||--|--------|||----------------|------------||--  1 [S] COG2013 Uncharacterized conserved protein
-------------|-------------||-------------|||---||-------------|--  1 [Q] COG2015 Alkyl sulfatase and related hydrolases
|-||---------||------|----||||----||-------------|||||||------||--  1 [E] COG2021 Homoserine acetyltransferase
----------------|-||||----|||||-----||----|||||-||--||||--||||||--  1 [H] COG2022 Uncharacterized enzyme of thiazole biosynthesis
--|---------------||-|----||||------|-----|||||-||||||||----------  1 [M] COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)
--------|---|-------|-----|-----|----|----|------||-----||--------  1 [I] COG2031 Short chain fatty acids transporter
|||||||||||||-----||||----|||||------|----|||-|-||-----|---|||||--  1 [H] COG2038 NaMN:DMB phosphoribosyltransferase
||------||||----|--------------------------------|----------------  1 [R] COG2044 Predicted peroxiredoxins
||----||-|----------------|---|-----|-----|||-|--|||-------||||---  1 [C] COG2055 Malate/L-lactate dehydrogenases
--------------------|-------------|-||----------||||-||-|||-------  1 [R] COG2056 Predicted permease
-|---------------|||||---||---------||-|--------||-----|---||-||--  1 [P] COG2059 Chromate transport protein ChrA
---|||------------||-|-----||-|---||------|||||--|-----|---||-||--  1 [P] COG2060 K+-transporting ATPase, A chain
--------|-|||---|-||------||||------------|||||-|||||--|--||||||--  1 [T] COG2062 Phosphohistidine phosphatase SixA
----------------||------------------------||||||||-----|||||||||--  1 [N] COG2063 Flagellar basal body L-ring protein
|||||||||||||-------------||--|--------------|---|-|---|---||-||--  1 [NU] COG2064 Flp pilus assembly protein TadC
------------------||||----|||-||||||||-----------|||---|----------  1 [F] COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase
------------------|||-----|---------||----|||||-||-----|---|||||--  1 [E] COG2066 Glutaminase
--------------|-----|------|||||||-|------|||----|--------||||||||  1 [R] COG2071 Predicted glutamine amidotransferases
----------------|---------|||-||-|||||-|--|||||-||||---||||-------  1 [O] COG2077 Peroxiredoxin
||||||--||||------|||------||-|----|----------|--|-----|---||||---  1 [H] COG2082 Precorrin isomerase
------------------||||----|||-|----|-|----|||-|-||-----|---||||---  1 [H] COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase
------------|--|-----|-|-|-||||---|||------------|---------||-|-||  1 [L] COG2094 3-methyladenine DNA glycosylase
---||||||-|||-------||----||||-----|||--------|--|-----|---|||||--  1 [S] COG2096 Uncharacterized conserved protein
||----------------|||------||-|----|----------|--|-----|---||||---  1 [H] COG2099 Precorrin-6x reductase
|-|||||||-------|-||||----|||||-----||----||--|-||--||||--||-|||--  1 [H] COG2104 Sulfur transfer protein involved in thiamine biosynthesis
-||---|---||------||-|--------------||----|||||-||-----|----------  1 [S] COG2105 Uncharacterized conserved protein
--||||||--|------|||||-----||-------------|||||-||-----|---||||---  1 [H] COG2109 ATP:corrinoid adenosyltransferase
||||--||---------|||-|----|-------||||----------||---------|||--||  1 [P] COG2111 Multisubunit Na+/H+ antiporter, MnhB subunit
--|----------|||--||----|-||||-------------------|---------||-||--  1 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)
---------|---|------|---------|||||||-----|||||-||||--------------  1 [P] COG2116 Formate/nitrite family of transporters
---|---------||---||-------||-------------------||-----|-------|--  1 [S] COG2119 Predicted membrane protein
------------------||-|----|||||-----------|||||-||--||||||||||||--  1 [S] COG2127 Uncharacterized conserved protein
---|---------|-----|------||||------|-----|||-|--|---------||||---  1 [S] COG2135 Uncharacterized conserved protein
-----------------|--||--|-||||||||||||----|||||-||||-|||---|------  1 [R] COG2137 Uncharacterized protein conserved in bacteria
----||--|---|--------|-----|||------------|||||-||--||||---|||||||  1 [C] COG2142 Succinate dehydrogenase, hydrophobic anchor subunit
---|-------------|||||----|---|--||-||----|||-|-||||||||--||||||--  1 [M] COG2148 Sugar transferases involved in lipopolysaccharide synthesis
--------------|---|-------|||--|-----|----|||-|-||-----------|----  1 [R] COG2153 Predicted acyltransferase
---|------||-||-|-||------||||------------------||--|--|----||||--  1 [H] COG2154 Pterin-4a-carbinolamine dehydratase
---|||------------||-|-----||-|---||------|||||--|-----|---||-||--  1 [P] COG2156 K+-transporting ATPase, c chain
---------------------------||-----|-||----|||-|--|------------||--  1 [Q] COG2162 Arylamine N-acetyltransferase
------------------||-|||---||-------------|||||-|||||------|||||--  1 [R] COG2166 SufE protein probably involved in Fe-S center assembly
|----------------|------------------------||||||||||--------------  1 [P] COG2168 Uncharacterized conserved protein involved in oxidation of intracellular sulfur
---|--------------||------|||-------------|||-|--|-----|----------  1 [S] COG2170 Uncharacterized conserved protein
---------|-------|--------||||||-|||||----||||||||||||||||||||||||  1 [E] COG2171 Tetrahydrodipicolinate N-succinyltransferase
-------------------|||----||||||||-|||----|||||-|||||||----|||||--  1 [D] COG2177 Cell division protein
--------|-|-|-------------|||-----|-|-----|||-|--|-----|-----|----  1 [C] COG2180 Nitrate reductase delta subunit
--------|-|---------------|||-----|-|-----|||-|--|-----|-----|----  1 [C] COG2181 Nitrate reductase gamma subunit
-------------|||---||---|-|---|||||||||---|||||-||||||||---||||---  1 [K] COG2183 Transcriptional accessory protein
---------------------------||----|--------|||-|--||-|||-||-||-|---  1 [D] COG2184 Protein involved in cell division
----------------|-||-------||--------------------|------------||--  1 [S] COG2187 Uncharacterized protein conserved in bacteria
--------------------|----||---||||||||-|||||||||||||---|-------|--  1 [G] COG2190 Phosphotransferase system IIA components
------------------||-|-----||-|---||------|||||-||-----|--|||-||--  1 [T] COG2205 Osmosensitive K+ channel histidine kinase
----------------||-|-|--||----|------|----------||-----|---|--|---  1 [T] COG2206 HD-GYP domain
----------------------||---------------------|--||||-||-----------  1 [C] COG2209 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE
|-||--||---------|---|----|-------||||----------||---------|||--|-  1 [P] COG2212 Multisubunit Na+/H+ antiporter, MnhF subunit
---|---------|||-|||-|--||----|---------|||||-|-||--|||-||||||||--  1 [O] COG2214 DnaJ-class molecular chaperone
---|||------------||-|-----||-|---||------|||||--|-----|--|||-||--  1 [P] COG2216 High-affinity K+ transport system, ATPase chain B
||||||||||||||---|||||----|||-|-||||||----|||||-||-||--|--|||||--|  1 [R] COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold
|-----||-|-------|--||--------|-||-||-----|||||--|--|------|||||--  1 [M] COG2222 Predicted phosphosugar isomerases
-----------|-||------|----||||-------|----|||||-||-----|---|||||--  1 [C] COG2224 Isocitrate lyase
----------||-|-------|----||||-------|----|||||-||-----|---|||||--  1 [C] COG2225 Malate synthase
--|-||----||-||-||||||||--||||----||||----|||||-||-|||||||||||||||  1 [H] COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis
-------------||---||-|--------------------|||||-||-|||||---|||||||  1 [H] COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase
--|-------------|----|----|||||-----------|||||-||-----|||||||||--  1 [M] COG2230 Cyclopropane fatty acid synthase and related methyltransferases
---|||-----|-------------|-||--|||||----|-----|-||----------|-|---  1 [E] COG2235 Arginine deiminase
|----------------||||-|||||||-|---|-||||-----|--||--|||----|||||||  1 [P] COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain)
-------------||------|---||---|-|---------|||||--|||-------|||||--  1 [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase
||||||--||||------|||-----|||-|----|----------|--|-----|---||||---  1 [H] COG2241 Precorrin-6B methylase 1
||||||--||||------|||-----|||-|----|----------|--|---------||||---  1 [H] COG2242 Precorrin-6B methylase 2
||||||--||||------|||------||-|----|----------|--|-----|---||||---  1 [H] COG2243 Precorrin-2 methylase
||||||||||-|-----|-|||----|---||||||||----|||||-||||||||---|||||--  1 [R] COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
---||||||||||-----||------||||||-||||-----|---|--|-----|------||--  1 [S] COG2246 Predicted membrane protein
-----------------||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG2255 Holliday junction resolvasome, helicase subunit
-------------||--|--||----|||||||||||||---|||||-||||||||||||||||--  1 [L] COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
-----------------|------|-----|-----||-----------|------|||----|--  1 [S] COG2257 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB
-------------------|-|----||||-||||-|-----|||||--|-----|---|||||--  1 [S] COG2261 Predicted membrane protein
-|||--||-||||---||||||||--||||||||||||----|||||-||-|||||---|||||--  1 [R] COG2262 GTPases
----------------||||||--------||||||||----|||||-||||||||||||||||--  1 [J] COG2264 Ribosomal protein L11 methylase
------------------||------|----|----||----|||-|--|------------|---  1 [S] COG2268 Uncharacterized protein conserved in bacteria
---|-------||-------||----|||--||---------|||||-|||----|---|||||--  1 [G] COG2301 Citrate lyase beta subunit
--------------------||----|----|||-||-----|||||--|-----|---|--||--  1 [S] COG2315 Uncharacterized protein conserved in bacteria
------------------|--|--------------||-----------|---------||||---  1 [S] COG2318 Uncharacterized protein conserved in bacteria
--||-----------------|-----|||------||----------||----------------  1 [S] COG2320 Uncharacterized conserved protein
---------------------|----|||---|---------|||||--|-|---|---||||---  1 [R] COG2321 Predicted metalloprotease
---|||-----||--------|----||||----||||-----------|-----|---||||---  1 [R] COG2329 Conserved protein involved in polyketide biosynthesis related to monooxygenase
--|------------------|--------------------|||||-|||||------|||||||  1 [O] COG2332 Cytochrome c-type biogenesis protein CcmE
---|---------------|-|--------||||||||----|||||-||||||||----------  1 [R] COG2333 Predicted hydrolase (metallo-beta-lactamase superfamily)
--------|----|-|---|||---||---|---||||-----------|---------|||||--  1 [S] COG2340 Uncharacterized protein with SCP/PR1 domains
------------------||||----|---|-----|-----|||||-||||-|||---|||||--  1 [S] COG2350 Uncharacterized protein conserved in bacteria
--------------|------|--------------||----|||-|--|-----|--||||||--  1 [R] COG2351 Transthyretin-like protein
------------------||-|----|--|--||--------|||||-||||-|||-------|--  1 [C] COG2352 Phosphoenolpyruvate carboxylase
----||---------------|----|||-----||------|||||-||--|||||||||-||--  1 [S] COG2353 Uncharacterized conserved protein
---------------------|----|||-------------|||-|-||---|-------|-|--  1 [S] COG2354 Uncharacterized protein conserved in bacteria
---------------------|--------------|-----||||||||----------------  1 [L] COG2356 Endonuclease I
------------------||-|--------------------|||||-||--||||--||||||--  1 [O] COG2360 Leu/Phe-tRNA-protein transferase
--------------|----|-|------------||||----|||||-||||-------|||||--  1 [S] COG2363 Uncharacterized small membrane protein
-------------||------|-----||--|---|---------|---|-----|---|---|--  1 [T] COG2365 Protein tyrosine/serine phosphatase
----------------|-||-|---------------------------|-----|---|--|---  1 [O] COG2370 Hydrogenase/urease accessory protein
------------------||-|----|-------|--||----|||---||----|||-||||---  1 [O] COG2371 Urease accessory protein UreE
-----------------|-|||--------------------|||||--|-||--|---||-||||  1 [R] COG2373 Large extracellular alpha-helical protein
------------------||-|--|-|-----|---------------||----------------  1 [R] COG2374 Predicted extracellular nuclease
---------------------|----|||-------------|||-|-||-----|---||-----  1 [P] COG2375 Siderophore-interacting protein
---------|--------||-|--------------------|||||-||||||||---|||||--  1 [O] COG2377 Predicted molecular chaperone distantly related to HSP70-fold metalloproteases
--------------------||----|||||---||||----|---|-||--|-||--||||||--  1 [K] COG2378 Predicted transcriptional regulator
----||||--|||----|---|---------------------------|-----|---||||---  1 [G] COG2379 Putative glycerate kinase
---------------------|----|---|---||||----|||-|--|----------------  1 [P] COG2382 Enterochelin esterase and related enzymes
--|-----|------------|--------------------|||||-|||||------|||||--  1 [O] COG2386 ABC-type transport system involved in cytochrome c biogenesis, permease component
--------|---|-------||----|----|--||------|||---||-|-------|||||--  1 [R] COG2388 Predicted acetyltransferase
-||---||--||-||----|-|----|---------------||||--||----------------  1 [T] COG2453 Predicted protein-tyrosine phosphatase
---------------------|----||||||||-|||-----------|---------|------  1 [TQ] COG2508 Regulator of polyketide synthase expression
||----||-|---------|-------------------------|---|---||----|-|----  1 [S] COG2510 Predicted membrane protein
||||--|||||||-|--|------------------------|||||-||--||||||||||||--  1 [O] COG2518 Protein-L-isoaspartate carboxylmethyltransferase
------------------||--------------|-|------------|-----|--||--|--|  1 [V] COG2602 Beta-lactamase class D
-|----------------------------------------|||-|--|--------|-------  1 [R] COG2603 Predicted ATPase
----------------|-||----------|------------------|---|||--||||||--  1 [R] COG2607 Predicted ATPase (AAA+ superfamily)
--||||--|--||||-||||||----|---|||-|||||-------|--|||-|||||-|||----  1 [P] COG2608 Copper chaperone
---------------------|----||||------------||||||||||||||------||--  1 [C] COG2609 Pyruvate dehydrogenase complex, dehydrogenase (E1) component
-|--------------|-------------|-----------------||-----|--|-------  1 [P] COG2703 Hemerythrin
--------------|---------------||-||||-----||||||-|-----|----------  1 [G] COG2706 3-carboxymuconate cyclase
------------------|-----------|-----||-----------|-----|----------  1 [R] COG2715 Uncharacterized membrane protein, required for spore maturation in B.subtilis.
-------------------|-|--|-----|-----------|||||--|-|---|--||||-|--  1 [S] COG2717 Predicted membrane protein
---|--------------------------|-----||----|||||-||----------|-|---  1 [S] COG2718 Uncharacterized conserved protein
---|--------------------------|-----||----|||||-||----------|-|---  1 [S] COG2719 Uncharacterized conserved protein
---------------------|----|---|-----||-----------|----------------  1 [V] COG2720 Uncharacterized vancomycin resistance protein
----------------||------------|-----||----|||||-||-----|----------  1 [KNU] COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor)
---|--------------------------|-----||----|||||-||----------|-|---  1 [T] COG2766 Putative Ser protein kinase
--------------|---||-|-----||-------------------||-----|---|||||--  1 [R] COG2802 Uncharacterized protein, similar to the N-terminal domain of Lon protease
----------------||||||--------|-----------|||||-||--||||----------  1 [NU] COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT
-------------|-------|--------------||-----------|--|--|------||--  1 [K] COG2808 Transcriptional regulator
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG2812 DNA polymerase III, gamma/tau subunits
--|----------||------|----|||-|-----------|||||-||||-------|||||--  1 [L] COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding
---------------------|--------|--|--|------||-|--|---|----||---|--  1 [R] COG2819 Predicted hydrolase of the alpha/beta superfamily
------------------||----------------------||||||||||-|||---|||||--  1 [M] COG2821 Membrane-bound lytic murein transglycosylase
--------------------------|----|||-|------|||||-||||-|||||||||||--  1 [P] COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism
----------------||---|||||----------------|||||-||||-|||-------|||  1 [M] COG2825 Outer membrane protein
---|----------------|----------|||||||----|||||-||---||-----||||--  1 [L] COG2827 Predicted endonuclease containing a URI domain
------------------------------------|-----|||---||--||||---||-|---  1 [S] COG2828 Uncharacterized protein conserved in bacteria
--------------------||-----------||-------|||-|-||||-||----|||----  1 [S] COG2832 Uncharacterized protein conserved in bacteria
-|||----|-------|----|--||----|-----||----|||||-||||||||||||||||||  1 [M] COG2834 Outer membrane lipoprotein-sorting protein
--||------|||-------------||||------------|||||-||-|||||----||||--  1 [S] COG2835 Uncharacterized conserved protein
---|---------------|----------|-----------------||---||||||-------  1 [S] COG2836 Uncharacterized conserved protein
-------------------|-|----|||-----|||-----|||||-||-|-|||------|---  1 [P] COG2837 Predicted iron-dependent peroxidase
--------------------------||||------------------||--|||---|-------  1 [C] COG2838 Monomeric isocitrate dehydrogenase
------------------------|-----------------||||||||||||||---|||||--  1 [S] COG2840 Uncharacterized protein conserved in bacteria
------------------------------------------|||----|-|-||-|||--|----  1 [S] COG2841 Uncharacterized protein conserved in bacteria
--------------------------|||-------------|||||-||||-|||---|||||--  1 [O] COG2844 UTP:GlnB (protein PII) uridylyltransferase
----------|-----|----|----|---------------------||-|-|||--||||||||  1 [S] COG2847 Uncharacterized protein conserved in bacteria
--------------------|-||------------|--------||--|---||---|-------  1 [S] COG2849 Uncharacterized protein conserved in bacteria
------------------------------------|-----|||||--|||||||----------  1 [S] COG2850 Uncharacterized conserved protein
--------------------------|-----|-|-||-----------|--|||---|-------  1 [C] COG2851 H+/citrate symporter
------------------------------------------|||||-||||||||--|----|||  1 [Q] COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component
--------|-----------|-----|----|||||------|||||--|||-|||--||||||--  1 [S] COG2855 Predicted membrane protein
-------------||-|-------------------||----------||--||||||||||||||  1 [C] COG2857 Cytochrome c1
---|------||---------|----|----||---||----|||||-||||---|--||||||--  1 [S] COG2860 Predicted membrane protein
-------------------------|-----------|----|||-|--|||------|||-||--  1 [S] COG2861 Uncharacterized protein conserved in bacteria
--|-------------|----|--------------------|||-||||||---|||||---|--  1 [S] COG2862 Predicted membrane protein
--|-----|-------|-------------------------|||||-||||---|--|-|-----  1 [C] COG2864 Cytochrome b subunit of formate dehydrogenase
-------------||---------------------------|||||-||-|||||---|||||||  1 [I] COG2867 Oligoketide cyclase/lipid transport protein
----------------------||---------------------|--||||-||-----------  1 [C] COG2869 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC
-|--------------|---|---------------------||||||-|||-||||||---||--  1 [M] COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase
----------------------||---------------------|--||||-||-----------  1 [C] COG2871 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF
--|-||||--||||---|--||--------|------|----------||-----|---||||---  1 [R] COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain
--||---------||--|---|----|||-||---|-|-----------|-|---|--|||||---  1 [E] COG2873 O-acetylhomoserine sulfhydrylase
||||||--||||------|||------||-|----|----------|--|-----|---||||---  1 [H] COG2875 Precorrin-4 methylase
----------------|---|-||------------------|||||-||||||||||||||||||  1 [M] COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase
--|--------------|--|---------------------||||||||||||||----------  1 [C] COG2878 Predicted NADH:ubiquinone oxidoreductase, subunit RnfB
------------------------------------------|||||--|---|||--|-------  1 [S] COG2879 Uncharacterized small protein
-----------------|------|-----|-----||----||||||||-----|----------  1 [NUO] COG2882 Flagellar biosynthesis chaperone
-------------------|-|----||||||||-|||----|||||-|||||||----|||||--  1 [D] COG2884 Predicted ATPase involved in cell division
-------------------|----|------|-|||||----|||||-|||||--|----------  1 [M] COG2891 Cell shape-determining protein
----------------||||||--------|----|||----||||||||--||||||-||||---  1 [D] COG2894 Septum formation inhibitor-activating ATPase
--------------------------|||-|-----------||||||||--||||---|||||--  1 [P] COG2895 GTPases - Sulfate adenylate transferase subunit 1
--|-----------------------||||-|--|||------------|--|--|---|||||--  1 [S] COG2898 Uncharacterized conserved protein
------------------------------------------|||||-|||||||----||||---  1 [S] COG2900 Uncharacterized protein conserved in bacteria
------------------------------------------||||||||||||||----------  1 [KL] COG2901 Factor for inversion stimulation Fis, transcriptional activator
-------------||------------|||------------------||--|------|||||||  1 [E] COG2902 NAD-specific glutamate dehydrogenase
------------------------------------------|||||-|||||--|--------||  1 [S] COG2904 Uncharacterized protein conserved in bacteria
--------|-------|---------|----------|----------||----------------  1 [T] COG2905 Predicted signal-transduction protein containing cAMP-binding and CBS domains
------------------|---------|-------------||-||-||--||||-------|--  1 [P] COG2906 Bacterioferritin-associated ferredoxin
-------------------------------|-|-||-----------||-----|--|||-|---  1 [R] COG2910 Putative NADH-flavin reductase
------------------------------------------||||||||||||||---|||||--  1 [S] COG2911 Uncharacterized protein conserved in bacteria
-------------------|--||------------------|||||||||||--|-------|--  1 [S] COG2912 Uncharacterized conserved protein
------------------------------------------||||||||||||||---|||||||  1 [J] COG2913 Small protein A (tmRNA-binding)
------------------------------------------||||||||||||||----------  1 [S] COG2914 Uncharacterized protein conserved in bacteria
------------------------------------------|||||||||||-------------  1 [R] COG2915 Uncharacterized protein involved in purine metabolism
------------------------------------------||||||||||-|||----||||||  1 [D] COG2917 Intracellular septation protein A
------------------------------|----|------||||||||-|--------------  1 [H] COG2918 Gamma-glutamylcysteine synthetase
------------------------||||||-|||||||----||||||||||||||---|||||||  1 [D] COG2919 Septum formation initiator
--------|-|-------------------------------||||||||||--------------  1 [P] COG2920 Dissimilatory sulfite reductase (desulfoviridin), gamma subunit
------------------------------------------||||||||||||||----------  1 [S] COG2921 Uncharacterized conserved protein
|-|--------------|------------------------||||||||||--------------  1 [P] COG2923 Uncharacterized protein involved in the oxidation of intracellular sulfur
------------------------------------------||||||||||||||----------  1 [CO] COG2924 Fe-S cluster protector protein
------------------------------------------|||||||||||--|----------  1 [L] COG2925 Exonuclease I
------------------------------------------|||||-||||||||---|||||||  1 [L] COG2927 DNA polymerase III, chi subunit
---|---------------||-||-------------|-----------|--||||---||-|---  1 [S] COG2928 Uncharacterized conserved protein
----------------|-||-------------------------|--||--||||---||-||--  1 [Q] COG2931 RTX toxins and related Ca2+-binding proteins
------------------------------------------|||||--||||-------------  1 [R] COG2933 Predicted SAM-dependent methyltransferase
-------------||---------------------------------||--|--|--||||||--  1 [O] COG2935 Putative arginyl-tRNA:protein arginylyltransferase
---------------------------|||------------|||||-|||||-------------  1 [I] COG2937 Glycerol-3-phosphate O-acyltransferase
-------------||---------------------------|||||-||||||||---|||||||  1 [S] COG2938 Uncharacterized conserved protein
-------------||----------------------------------|--|--|-------|||  1 [H] COG2941 Ubiquinone biosynthesis protein COQ7
------------------------------------------|||-|-||--|--|-------|--  1 [M] COG2943 Membrane glycosyltransferase
---|----|----------------------------------------|--||||---|||||||  1 [R] COG2945 Predicted hydrolase of the alpha/beta superfamily
--------------|---||-|---------------------------|--|--|---||||---  1 [S] COG2947 Uncharacterized conserved protein
---------------------|---------|-|-----------|---|--|---|||----|--  1 [E] COG2957 Peptidylarginine deiminase and related enzymes
-------------------------------------------------|--|--||||-------  1 [S] COG2958 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||-|||----------  1 [H] COG2959 Uncharacterized enzyme of heme biosynthesis
------------------------------------------|||||-||--||||---||||---  1 [S] COG2960 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||||||---|||||-|  1 [R] COG2961 Protein involved in catabolism of external DNA
--------------------|-----------|---------|||||-||||---|--|-|-----  1 [S] COG2964 Uncharacterized protein conserved in bacteria
---------------------|--------------------|||||-||--|--|---|||||--  1 [P] COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport
------------------------------------------|||||-||||||||----------  1 [R] COG2969 Stringent starvation protein B
--------------------|---------|-||||||----------||--|--|----------  1 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain
------------------------------------------|||||-||||||||----------  1 [L] COG2974 DNA recombination-dependent growth factor C
------------------------------------------|||||-|||--|||----------  1 [S] COG2975 Uncharacterized protein conserved in bacteria
------------------------------------------||||||||||||||----------  1 [S] COG2976 Uncharacterized protein conserved in bacteria
--------------------------||||------------|||||-||---------|-||---  1 [Q] COG2977 Phosphopantetheinyl transferase component of siderophore synthetase
------------------------------------------|||-|-||-|-||----||||---  1 [S] COG2979 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||||||----------  1 [M] COG2980 Rare lipoprotein B
------------------|-----------------------|||||-||||-------||||---  1 [E] COG2981 Uncharacterized protein involved in cysteine biosynthesis
-|----------------------------------------|||||-||||-------|||||--  1 [S] COG2983 Uncharacterized conserved protein
---|||--------------||----------|-|-||-------|--||-----|---|||||--  1 [E] COG2987 Urocanate hydratase
------------------||----------------------|||||-||----------------  1 [E] COG2988 Succinylglutamate desuccinylase
---------------------------------------------|--||||-||-----------  1 [S] COG2991 Uncharacterized protein conserved in bacteria
--------------------|---------||||||||----------||----------------  1 [S] COG2996 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||------|||-----  1 [C] COG3005 Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit
------------------------------|--------------|--||--|-------------  1 [S] COG3007 Uncharacterized paraquat-inducible protein B
------------------------------------------|||||-||||-|||----------  1 [R] COG3008 Paraquat-inducible protein B
------------------------------------------|||||-||---|||----------  1 [S] COG3009 Uncharacterized protein conserved in bacteria
------------------||--------------|-||-------|--||--|--|------||--  1 [S] COG3011 Uncharacterized protein conserved in bacteria
---------------------|----|---------------|||||-||||-|-|----------  1 [S] COG3012 Uncharacterized protein conserved in bacteria
----------------|-------------------------------||--------|-------  1 [S] COG3016 Uncharacterized iron-regulated protein
------------------------------------------|||||-||||||||----------  1 [M] COG3017 Outer membrane lipoprotein involved in outer membrane biogenesis
----------|-----|-------------------------------||-|------|-|-----  1 [R] COG3019 Predicted metal-binding protein
----------------|---|-----|-----||--------|||||-||||-|||--|----|-|  1 [S] COG3022 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||-|||----||||--  1 [S] COG3024 Uncharacterized protein conserved in bacteria
--|---------------------------------------|||||-||||---|------||--  1 [S] COG3025 Uncharacterized conserved protein
------------------------------------------|||||-||||---|----------  1 [T] COG3026 Negative regulator of sigma E activity
-----------------------|------|---||||----|||||-|||||||----|||||||  1 [S] COG3027 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||||||----------  1 [S] COG3028 Uncharacterized protein conserved in bacteria
--||----------------------||-------|||----|||||-||-|-||----||||---  1 [R] COG3030 Protein affecting phage T7 exclusion by the F plasmid
----------------|-------------------------|||||-||------|||||||---  1 [S] COG3034 Uncharacterized protein conserved in bacteria
------------------------------------------|--||-||||-|------------  1 [S] COG3036 Uncharacterized protein conserved in bacteria
--------------------------|---------------|||-|-||--------||--||--  1 [M] COG3040 Bacterial lipocalin
------------------------------------------|||||-||||------|||-----  1 [C] COG3043 Nitrate reductase cytochrome c-type subunit
------------------------------------------|||||-||---|||---||||---  1 [S] COG3045 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||-||--|---|-|||||  1 [M] COG3047 Outer membrane protein W
--------------------|---------------||----|||-|-||----------------  1 [E] COG3048 D-serine dehydratase
----------------|-------------------------|||||--|||--------|-----  1 [O] COG3058 Uncharacterized protein involved in formate dehydrogenase formation
------------------------------------------|||||-||||------|||-----  1 [P] COG3062 Uncharacterized protein involved in formation of periplasmic nitrate reductase
---------------------------------------------|--||||||||----------  1 [NU] COG3063 Tfp pilus assembly protein PilF
------------------------------------------|||||-||||--------------  1 [P] COG3067 Na+/H+ antiporter
------------------------------|--|||------|||||-||||-|-|----|-||-|  1 [K] COG3070 Regulator of competence-specific genes
------------------------------------------|||||-||||||||----------  1 [H] COG3071 Uncharacterized enzyme of heme biosynthesis
------------------------------------------|||||-||||--------------  1 [F] COG3072 Adenylate cyclase
------------------------------------------|||||-|||||--|----------  1 [T] COG3073 Negative regulator of sigma E activity
------------------------------------------|||||-|||||-------------  1 [S] COG3079 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||--------------  1 [R] COG3081 Nucleoid-associated protein
------------------------------------------|||||-||||--------------  1 [R] COG3083 Predicted hydrolase of alkaline phosphatase superfamily
-----------------|--|---------------------|||||-||||--------------  1 [T] COG3086 Positive regulator of sigma E activity
------------------------------------------|||||-||||||||----------  1 [D] COG3087 Cell division protein
---------------------|--------------------|||||--||||------|||||--  1 [O] COG3088 Uncharacterized protein involved in biosynthesis of c-type cytochromes
------------------------------------------|||||-||||--------------  1 [S] COG3089 Uncharacterized protein conserved in bacteria
-------------------------------|||||||----|||||-||||--------------  1 [S] COG3091 Uncharacterized protein conserved in bacteria
-------------------||-----|---------------|||---|||-|-------|-||--  1 [R] COG3093 Plasmid maintenance system antidote protein
------------------------------------------|||||-||||--------------  1 [S] COG3098 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||--------------  1 [S] COG3100 Uncharacterized protein conserved in bacteria
-----------------------------------||-----|||||-||||--------------  1 [T] COG3103 SH3 domain protein
------------------------------------------|||||-||||--------------  1 [S] COG3105 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|||||-------------  1 [R] COG3107 Putative lipoprotein
------------------------------------------|||||-||||--------------  1 [T] COG3109 Activator of osmoprotectant transporter ProP
------------------------------------------|||||-||||--------------  1 [S] COG3111 Uncharacterized conserved protein
------------------------------------------|||||-||||--------------  1 [U] COG3114 Heme exporter protein D
------------------------------------------|||||-|||||-------------  1 [D] COG3115 Cell division protein
------------------------------------------|||||||||||--|----------  1 [D] COG3116 Cell division protein
------------------------------------------|||||-||||||||----------  1 [S] COG3117 Uncharacterized protein conserved in bacteria
--------------------------||||------------|||||-|||||--|---|||||--  1 [O] COG3118 Thioredoxin domain-containing protein
------------------------------------------|||||--|--|-------------  1 [S] COG3122 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||-----|----------  1 [S] COG3123 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||----------------  1 [S] COG3124 Uncharacterized protein conserved in bacteria
----------------------------------||||----||||||-|--|--|---|-|||--  1 [C] COG3125 Heme/copper-type cytochrome/quinol oxidase, subunit 4
------------------------------------------|||||-||-----|---|||||--  1 [Q] COG3127 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component
------------------------------------------|||----|--|---------||--  1 [S] COG3128 Uncharacterized iron-regulated protein
--------------|---------------------------|||||-||----------------  1 [R] COG3129 Predicted SAM-dependent methyltransferase
------------------------------------------|||||-||----------------  1 [J] COG3130 Ribosome modulation factor
------------------------------------------|||-|-||--|--|----------  1 [P] COG3131 Periplasmic glucans biosynthesis protein
------------------------------------------|||||-||------------|---  1 [S] COG3132 Uncharacterized protein conserved in bacteria
------------------------------------------|||||--|||---|----------  1 [M] COG3133 Outer membrane lipoprotein
------------------------------------------|||||--|--|-------------  1 [S] COG3134 Predicted outer membrane lipoprotein
---------------------|----|---------------|||-|-||----------|||---  1 [Q] COG3135 Uncharacterized protein involved in benzoate metabolism
------------------------------------------|||||-||------------|---  1 [R] COG3136 Uncharacterized membrane protein required for alginate biosynthesis
------------------------------------------|||||-||----------------  1 [S] COG3139 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||----------------  1 [S] COG3141 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||-----|----------  1 [NT] COG3143 Chemotaxis protein
-----------------|------------|-----||----||||||||-----|----------  1 [N] COG3144 Flagellar hook-length control protein
--------------|----|------||||------------|||-|-||--|--|---|||||--  1 [L] COG3145 Alkylated DNA repair protein
------------------||-----------------------------|--|--|---|||||--  1 [S] COG3146 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||--|--|----------  1 [S] COG3147 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||-|---|----------  1 [R] COG3150 Predicted esterase
------------------------------------------|||||-||--|-------------  1 [S] COG3151 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||-----|---|||----  1 [I] COG3154 Putative lipid carrier protein
------------------------------------------|||||-||----------------  1 [Q] COG3155 Uncharacterized protein involved in an early stage of isoprenoid biosynthesis
--|-----------------------|----||---------|||||-||--|--|---|||||--  1 [P] COG3158 K+ transporter
------------------------------------------|||||-||-||--|-------|--  1 [S] COG3159 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||----------------  1 [K] COG3160 Regulator of sigma D
|||-----||-----------------|||------------|||||-||-|-|||----------  1 [H] COG3161 4-hydroxybenzoate synthetase (chorismate lyase)
---------------------|----|---------|-----|||||--|--|-------------  1 [S] COG3162 Predicted membrane protein
------------------------------------------|||||-||--|--|----------  1 [S] COG3164 Predicted membrane protein
------------------------------------------|||||-||-|||||----------  1 [S] COG3165 Uncharacterized protein conserved in bacteria
------------------||----------------------|||||-||--||||------|---  1 [NU] COG3166 Tfp pilus assembly protein PilN
------------------------------------------------||--||||----------  1 [NU] COG3167 Tfp pilus assembly protein PilO
------------------------------------------------||--||||----------  1 [NU] COG3168 Tfp pilus assembly protein PilP
---------------------|--------------------------||--|-------||----  1 [S] COG3169 Uncharacterized protein conserved in bacteria
---------------------------||--|----------|||||--|||--------------  1 [H] COG3172 Predicted ATPase/kinase involved in NAD metabolism
--||-----------------|-----||--|---|||-----------|-----|---||-||-|  1 [R] COG3173 Predicted aminoglycoside phosphotransferase
|-||-----|--|---|--------------------------------|-----|----|-|---  1 [S] COG3174 Predicted membrane protein
-------------||----------------------------------|-----|---|||||||  1 [O] COG3175 Cytochrome oxidase assembly factor
-------------------|-------||-------------------||-----|---|||||--  1 [R] COG3176 Putative hemolysin
--||------------|--||-----|-----|-||-------|||---|-|-|||||-||-|--|  1 [S] COG3177 Uncharacterized conserved protein
-------------------------------------------------|--||||---|||||--  1 [R] COG3178 Predicted phosphotransferase related to Ser/Thr protein kinases
---------------------|------------------------|--||---------|-----  1 [R] COG3179 Predicted chitinase
-------------------||-----|-------|-||----|||-|-||---------||-|---  1 [R] COG3180 Putative ammonia monooxygenase
--|------------------|------------------------|-||------------|---  1 [V] COG3183 Predicted restriction endonuclease
-------------------------------------------------|--|||----||||---  1 [S] COG3184 Uncharacterized protein conserved in bacteria
-----------------------|------------------------||-----|------||--  1 [E] COG3186 Phenylalanine-4-hydroxylase
--|---------------|-||----|---------------|||||-||-----||||||||---  1 [O] COG3187 Heat shock protein
----||-----|--------------|||-----|-------|||-|--|-----|---||||---  1 [S] COG3189 Uncharacterized conserved protein
----------------------||------------||----||||||||-----|----------  1 [N] COG3190 Flagellar biogenesis protein
------||---|---------|----||||-------------------|-----|---|||||--  1 [EQ] COG3191 L-aminopeptidase/D-esterase
--------------------|--------------||-----|||-|--|----------------  1 [E] COG3192 Ethanolamine utilization protein
-------------||---------------------------|||-|--|---------||||---  1 [F] COG3194 Ureidoglycolate hydrolase
---------------------|----|---------||-----------|-----|---|||||--  1 [S] COG3195 Uncharacterized protein conserved in bacteria
---------------------------||-------------|------|----------------  1 [S] COG3196 Uncharacterized protein conserved in bacteria
------------------------------------------------||---||||||-|-||--  1 [P] COG3197 Uncharacterized protein, possibly involved in nitrogen fixation
------------------------------------------------||---||-----------  1 [S] COG3198 Uncharacterized protein conserved in bacteria
--------------------------|----|||--------|||||--|||----||--------  1 [H] COG3201 Nicotinamide mononucleotide transporter
----------------||||----------------------|||-|-||-||--|---|||||--  1 [M] COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis
-------------|----------------------------------||----------------  1 [Q] COG3207 Pyoverdine/dityrosine biosynthesis protein
-------------------|-----------------|----------||--------|||-||--  1 [R] COG3211 Predicted phosphatase
------------------------------------------------||---|||---|||----  1 [P] COG3213 Uncharacterized protein involved in response to NO
---------------------|-----||-------------|||-|--|---------||-||--  1 [S] COG3214 Uncharacterized protein conserved in bacteria
-------------------------------------------------|--||||----------  1 [NU] COG3215 Tfp pilus assembly protein PilZ
------------------|-----------------------------||---------||||---  1 [S] COG3216 Uncharacterized protein conserved in bacteria
---|---------------|----------------------|||||-||---------||-||--  1 [R] COG3217 Uncharacterized Fe-S protein
-------------------------------------------------|--|-----||||||--  1 [R] COG3218 ABC-type uncharacterized transport system, auxiliary component
------------------||-------||--------------------|----------------  1 [S] COG3222 Uncharacterized protein conserved in bacteria
-------------------------------|---||-----|||||--||---------------  1 [S] COG3223 Predicted membrane protein
------------------||-|---------------------------|----------------  1 [S] COG3224 Uncharacterized protein conserved in bacteria
---------------------------||-------------|||-|--|----------------  1 [S] COG3226 Uncharacterized protein conserved in bacteria
--|----------------|----------|---|-|-----------||----------------  1 [E] COG3227 Zinc metalloprotease (elastase)
------------------||----------------------|||||--|-----|----------  1 [S] COG3228 Uncharacterized protein conserved in bacteria
---------------------|-----||--|-----------------|----------|-|---  1 [J] COG3231 Aminoglycoside phosphotransferase
-|----||------------------|||--------------------|-----|----------  1 [R] COG3233 Predicted deacetylase
-----------------|------------------------|||----|-----|----------  1 [S] COG3234 Uncharacterized protein conserved in bacteria
------------------------------------------------||---||-----------  1 [S] COG3235 Predicted membrane protein
-------------------|-|----|---------------|------|----------------  1 [S] COG3236 Uncharacterized protein conserved in bacteria
-------------------|------|----||||||-----|||-|--|---------||-||--  1 [S] COG3237 Uncharacterized protein conserved in bacteria
-------------------------------------------------|--|||-----------  1 [C] COG3241 Azurin
------------------------------------------|||||-||--|--|-----||---  1 [S] COG3242 Uncharacterized protein conserved in bacteria
--------|-----------||-----|---------------------|-----|---||-|---  1 [S] COG3246 Uncharacterized conserved protein
--|----------------|-------||--|--||------||||---|-----|----|||---  1 [S] COG3247 Uncharacterized conserved protein
------------------------------------------|||-|-||----------------  1 [M] COG3248 Nucleoside-binding outer membrane protein
------------------------------------------------||--|---------|---  1 [S] COG3249 Uncharacterized protein conserved in bacteria
---------------------------||-------|------|--|--|-----|---|------  1 [S] COG3251 Uncharacterized protein conserved in bacteria
----||--|-|||---|--------------------|-----------|------------||--  1 [I] COG3255 Putative sterol carrier protein
----------||------|------------------------------|---|||---|||----  1 [P] COG3256 Nitric oxide reductase large subunit
---------------------|--------------------|||-|--|---------||||---  1 [R] COG3257 Uncharacterized protein, possibly involved in glyoxylate utilization
--------------------|----------------|----|||-|-||---------|--|---  1 [P] COG3263 NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain
-------------||----|-|----|---------------|||||-||-|-|||---||-|---  1 [G] COG3265 Gluconate kinase
------------------------------------------|||||-||----------------  1 [S] COG3266 Uncharacterized protein conserved in bacteria
---|-----------|--|--------|||-------------------|-----------|----  1 [S] COG3268 Uncharacterized conserved protein
|-|---------------------------------------|||||-||----------------  1 [S] COG3272 Uncharacterized conserved protein
-||-||---|-|----|-------------------------|||-|--|||------|-|-----  1 [J] COG3276 Selenocysteine-specific translation elongation factor
--------------------|---------||||||||----|||||-||--|--|---|||||--  1 [KT] COG3279 Response regulator of the LytR/AlgR family
-----------|-------|-|----|||-----------------|--|-----|----|-----  1 [G] COG3280 Maltooligosyl trehalose synthase
------------|-------------|||--------------------|-----|----------  1 [G] COG3281 Uncharacterized protein, probably involved in trehalose biosynthesis
---------------------------||-------||-----------|---------||-|---  1 [L] COG3285 Predicted eukaryotic-type DNA primase
-|-------|---------|----------------------------||----------|-|---  1 [S] COG3287 Uncharacterized conserved protein
------------------||-|------------|--------------|----------------  1 [S] COG3296 Uncharacterized protein conserved in bacteria
------------------------------------------|--|--||-------------|--  1 [U] COG3297 Type II secretory pathway, component PulL
-----------------||||---------|--||-------|||||-||||||||||-|||||||  1 [M] COG3307 Lipid A core - O-antigen ligase and related enzymes
------------------------------------------------||---|||----------  1 [S] COG3308 Predicted membrane protein
------------------------------------------|||||-||||-||-----------  1 [C] COG3312 F0F1-type ATP synthase, subunit I
------------------------------------------|||||-||||-|||----------  1 [M] COG3317 Uncharacterized lipoprotein
----------------------||------------|-----|||-|-||---||-----------  1 [R] COG3318 Predicted metal-binding protein related to the C-terminal domain of SecA
-------------||----|-------|||----|--------------|---------|------  1 [Q] COG3320 Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes
--------------------|-----||-||---||||-----------|----------------  1 [S] COG3323 Uncharacterized protein conserved in bacteria
--|-----------------------|||--------|--------|-||-|---|---|||||--  1 [R] COG3324 Predicted enzyme related to lactoylglutathione lyase
--|----------------------------|||-|||--------|--|---||-|--|------  1 [S] COG3326 Predicted membrane protein
-------------|-----------------------|-----------|-----|----------  1 [S] COG3332 Uncharacterized conserved protein
---|------|||------------------------|-----------|----------------  1 [S] COG3342 Uncharacterized conserved protein
--|----------|----|||------||-|---|--|----|--||-||----------|-----  1 [L] COG3344 Retron-type reverse transcriptase
-------------||-----------||||-------------------|-----|---|||||||  1 [S] COG3346 Uncharacterized conserved protein
---|-----------------------||--------------------|-----|----|-----  1 [S] COG3360 Uncharacterized conserved protein
---|--------------||-----------------------------|-----|----------  1 [R] COG3380 Predicted NAD/FAD-dependent oxidoreductase
---------||||-----------------|||---||--------|--|-----|------|---  1 [S] COG3382 Uncharacterized conserved protein
----||-----|-|-------|------------|-|---------|--|-||--|---|||||--  1 [G] COG3386 Gluconolactonase
--|-|------|-------|-|--||-||-|-----||----|||-|--|-----|----|-|---  1 [S] COG3391 Uncharacterized conserved protein
-------------------------------|---|-|-------|--||----------------  1 [S] COG3397 Uncharacterized protein conserved in bacteria
-----------------------------------------------|-|--|--|---|------  1 [S] COG3416 Uncharacterized protein conserved in bacteria
------------------------------------------||||||||----------------  1 [NUO] COG3418 Flagellar biosynthesis/type III secretory pathway chaperone
-------------------------------------------------|--|-||----------  1 [NU] COG3419 Tfp pilus assembly protein, tip-associated adhesin PilY1
----------|--------------------------------------|---|||----||----  1 [P] COG3420 Nitrous oxidase accessory protein
--|---------------------------------------||||---|-|-||----|-|||--  1 [S] COG3422 Uncharacterized conserved protein
---------------------------||-------|-----|||||-||-----------|----  1 [Q] COG3433 Aryl carrier domain
-----------|--------------|----------|-----||-|--|-----|----------  1 [Q] COG3435 Gentisate 1,2-dioxygenase
------------------||----------------------|||-|--|----------|-|---  1 [T] COG3447 Predicted integral membrane sensor domain
------------------|------------------------------|-----|---||-|---  1 [T] COG3448 CBS-domain-containing membrane protein
-------------------|----------------------||||---|---------||||---  1 [P] COG3454 Metal-dependent hydrolase involved in phosphonate metabolism
-------------------------------|---|------------||----------------  1 [G] COG3469 Chitinase
-------------------------------------------------|-|-|||----------  1 [S] COG3471 Predicted periplasmic/secreted protein
---------------------|---------------------------|-----|------||--  1 [E] COG3483 Tryptophan 2,3-dioxygenase (vermilion)
------------------|------------------------------|-----|------|---  1 [O] COG3484 Predicted proteasome-type protease
---|----------|----|-----------------|-------|---|-----|----|-|---  1 [Q] COG3486 Lysine/ornithine N-monooxygenase
------------------------------------------------||---------||-|---  1 [P] COG3487 Uncharacterized iron-regulated protein
------------------------------------------------||---------||-|---  1 [C] COG3488 Predicted thiol oxidoreductase
------------------------------------------------||---------||-|---  1 [R] COG3489 Predicted periplasmic lipoprotein
------------------------------------------------||---------||-|---  1 [S] COG3490 Uncharacterized protein conserved in bacteria
------------------------------------------------||---------||-||--  1 [S] COG3492 Uncharacterized protein conserved in bacteria
-------------------|-----------------------||||--|--|--|---|--|---  1 [R] COG3497 Phage tail sheath protein FI
-------------------------------------------||-|--|--|--|----------  1 [R] COG3498 Phage tail tube protein FII
-------------------------------------------||-|--|--|--|---|------  1 [R] COG3499 Phage protein U
-------------------|----------------------|||-|--|--|--|---|--|---  1 [R] COG3500 Phage protein D
|-|-----|----------------------------------------|-----|---|||||--  1 [S] COG3503 Predicted membrane protein
-----------|------------------------------------||-----|----|-||--  1 [Q] COG3508 Homogentisate 1,2-dioxygenase
--------------------------||||-------------------|-----|---||-||--  1 [Q] COG3509 Poly(3-hydroxybutyrate) depolymerase
------------------------------------------------||---------||||---  1 [O] COG3526 Uncharacterized protein conserved in bacteria
-------------------------------------------|-||-||----------------  1 [R] COG3529 Predicted nucleic-acid-binding protein containing a Zn-ribbon domain
-------------------------------------------|-||-||-----|----------  1 [S] COG3530 Uncharacterized protein conserved in bacteria
-------------------|------|---------|------------|----------|-||--  1 [P] COG3540 Phosphodiesterase/alkaline phosphatase D
-|-----------------|----------|-----|------------|-----|------|---  1 [R] COG3541 Predicted nucleotidyltransferase
---------------------|------------|-||-----------|-----|---|||||--  1 [R] COG3545 Predicted esterase of the alpha/beta hydrolase fold
----------|--------|----------|-----||-----||-|--|----------------  1 [P] COG3546 Mn-containing catalase
-------------------------------------|-----------|------------|---  1 [S] COG3551 Uncharacterized protein conserved in bacteria
------------------------------------------------||-----------|||--  1 [S] COG3553 Uncharacterized protein conserved in bacteria
---------------------------||--------------------|----------|-|---  1 [S] COG3554 Uncharacterized protein conserved in bacteria
------------------|------------------------------|-----|------|---  1 [S] COG3556 Predicted membrane protein
------------------|------------------------------|---------|--|---  1 [S] COG3558 Uncharacterized protein conserved in bacteria
-------------|----------------||--||-------------|---||----|-|----  1 [R] COG3560 Predicted oxidoreductase related to nitroreductase
------------------|------------------------------|---------|--|---  1 [R] COG3565 Predicted dioxygenase of extradiol dioxygenase family
-------------||------|---------------------------|---------||-|---  1 [L] COG3569 Topoisomerase IB
---------------------|---------------------------|---------||-|---  1 [V] COG3570 Streptomycin 6-kinase
---------------------------||--------------------|----------|-|---  1 [R] COG3571 Predicted hydrolase of the alpha/beta-hydrolase fold
|||----------------|||-----|||--|----------------|---------||-||--  1 [R] COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase
--|----------------|-----------------------------|||---|------|---  1 [H] COG3585 Molybdopterin-binding protein
-||---------------|-|---------------------|||||-||-|-------|--|---  1 [L] COG3593 Predicted ATP-dependent endonuclease of the OLD family
--|---------------------------|---|||------------|--|---------|---  1 [G] COG3594 Fucose 4-O-acetylase and related acetyltransferases
------------------------------------------------||----------|-||--  1 [S] COG3602 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||---------|||||--  1 [T] COG3605 Signal transduction protein containing GAF and PtsI domains
|--|-----|--------------------------------------||---------||||---  1 [R] COG3608 Predicted deacylase
------------------|--|--------------------------||------------|---  1 [T] COG3614 Predicted periplasmic ligand-binding sensor domain
-------------||-----|-----|||--------------------|-----|---|||||--  1 [E] COG3616 Predicted amino acid aldolase or racemase
---------------------------------------------|---|-----|--|||||---  1 [R] COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold
--|---------------|-|------||-||||-||------------|-----|---||||---  1 [S] COG3619 Predicted membrane protein
-------------------|----------------------||||---|---------||-|---  1 [P] COG3624 Uncharacterized enzyme of phosphonate metabolism
-------------------|----------------------||||---|---------||-|---  1 [P] COG3625 Uncharacterized enzyme of phosphonate metabolism
-------------------|----------------------||||---|---------||-|---  1 [P] COG3626 Uncharacterized enzyme of phosphonate metabolism
-------------------|----------------------||||---|---------||-|---  1 [P] COG3627 Uncharacterized enzyme of phosphonate metabolism
-------------------|-------------------------||--|--|--|------|---  1 [R] COG3628 Phage baseplate assembly protein W
--------------------------------|---------|||||-||||-||---|-------  1 [E] COG3633 Na+/serine symporter
-------------------------------||-|-|-----|||-|--|--|--|-------|--  1 [O] COG3634 Alkyl hydroperoxide reductase, large subunit
---------------------|---------------------------|-----|-------|--  1 [S] COG3644 Uncharacterized protein conserved in bacteria
-------------------|----------------------------||-------------|--  1 [S] COG3650 Predicted membrane protein
-------------------|-------------|-----|-----||-||---|-------|-|--  1 [R] COG3654 Prophage maintenance system killer protein
---------------------------||--------------------|-----|-------|--  1 [S] COG3662 Uncharacterized protein conserved in bacteria
----------------------------------||-|-----------|----------|--|--  1 [G] COG3664 Beta-xylosidase
-------------------------------------------------|--|--|-------|--  1 [P] COG3667 Uncharacterized protein involved in copper resistance
------------------------------------------------||---------|||||--  1 [S] COG3672 Predicted periplasmic protein
-------------|-----------------------------------|-------------|--  1 [S] COG3673 Uncharacterized conserved protein
------------------||----------------------|||||-||----||----|-----  1 [UNTP] COG3678 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein
-------------------|----------------------|||-|--|---------||-|---  1 [S] COG3685 Uncharacterized protein conserved in bacteria
-------------------|-----------------------------|---|||---|-|-|--  1 [S] COG3686 Predicted membrane protein
--------------|------|----|||--|---|------|||||-||----------------  1 [L] COG3695 Predicted methylated DNA-protein cysteine methyltransferase
----------------|-||----------------------|||-|--|-----|||--|--|--  1 [P] COG3696 Putative silver efflux pump
----------------|-||-|--------||---|||-----------|---|||---|||||--  1 [E] COG3705 ATP phosphoribosyltransferase involved in histidine biosynthesis
--------------------|---------|---||||-----------|-|-------||-|---  1 [S] COG3708 Uncharacterized protein conserved in bacteria
------------------------------------------||||---|---------||||---  1 [P] COG3709 Uncharacterized component of phosphonate metabolism
-------------------------------------------|||---|-----|----|-|---  1 [P] COG3720 Putative heme degradation protein
------------------------------------------|||||--|-------------|--  1 [E] COG3724 Succinylarginine dihydrolase
------------------------------------------|||||--|--|-------------  1 [V] COG3725 Membrane protein required for beta-lactamase induction
------------------------------------------|||||-||-|--------------  1 [R] COG3726 Uncharacterized membrane protein affecting hemolysin expression
-------------------------------||-|||------|||---|------------|---  1 [L] COG3728 Phage terminase, small subunit
------------------------------------------|||-|--|-|-----------|--  1 [S] COG3738 Uncharacterized protein conserved in bacteria
---------------------|-----------------------|---|---------|||||--  1 [E] COG3741 N-formylglutamate amidohydrolase
-------------------------------------------------|-----|---||-||--  1 [U] COG3745 Flp pilus assembly protein CpaB
-------------------------------------------------|-----|---|||||--  1 [S] COG3748 Predicted membrane protein
-------------|||--||----------------------------||-------------|--  1 [O] COG3751 Predicted proline hydroxylase
------------------------------------------|||----|-----|----|||---  1 [S] COG3753 Uncharacterized protein conserved in bacteria
-------------------|-|--------------------|||-|--|---------||-||--  1 [S] COG3755 Uncharacterized protein conserved in bacteria
--------------------|-----------|---------||||---|-----|---||||---  1 [S] COG3758 Uncharacterized protein conserved in bacteria
-------------------------------|-----------------|---------|||||--  1 [S] COG3760 Uncharacterized conserved protein
-------------||----------------------------------|-----------|-|--  1 [S] COG3777 Uncharacterized conserved protein
------------------------------------------------||---||-----------  1 [S] COG3782 Uncharacterized protein conserved in bacteria
------------------------------------------|||||--|-------------|--  1 [S] COG3784 Uncharacterized protein conserved in bacteria
------------------------------------------|||-|--|-------------|--  1 [S] COG3789 Uncharacterized protein conserved in bacteria
-------------------------------------------------|---------|||||--  1 [S] COG3802 Uncharacterized protein conserved in bacteria
----------------------------------------------|--|----------|-||--  1 [S] COG3811 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|------||--  1 [S] COG3812 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|---||-||--  1 [S] COG3813 Uncharacterized protein conserved in bacteria
-------------------------------------------------|---------|||||--  1 [S] COG3816 Uncharacterized protein conserved in bacteria
-------------------------------------------------|---------||-||--  1 [S] COG3821 Predicted membrane protein
-------------------|-----------------------------|-----|------||--  1 [S] COG3825 Uncharacterized protein conserved in bacteria
-||-----|||---------------||||||-|-|-------------|---||-----------  1 [T] COG3830 ACT domain-containing protein
--|--------------|--------|||-|---||||-----------|-----|---||-||--  1 [S] COG3832 Uncharacterized conserved protein
------------------------------|-----||----|||||-|||---------------  1 [KT] COG3835 Sugar diacid utilization regulator
---------------------|------------|-------|||||--|-|---|---||||---  1 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase
---|---------|-------|---------------------------|-----|------|---  1 [E] COG3844 Kynureninase
---|--|||-|-|----|-|-|--||----||||-||-||||-------|-----|---||||---  1 [R] COG3845 ABC-type uncharacterized transport systems, ATPase components
-------------------------------------------------|-|---|---||-||--  1 [U] COG3847 Flp pilus assembly protein, pilin Flp
------------------------------------------|||||-||||-|||----------  1 [T] COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific
------------------------------------------|||||-||--|--|---|||||--  1 [T] COG3852 Signal transduction histidine kinase, nitrogen specific
----------------|----|--------|------------------|-----|----------  1 [S] COG3868 Uncharacterized conserved protein
------------------|-----------------------|||||--|-----|---|||----  1 [R] COG3895 Predicted periplasmic protein
-------------------------------------------------|---|||----||----  1 [K] COG3901 Regulator of nitric oxide reductase transcription
-------------------------------------------------|----------|-|---  1 [S] COG3904 Predicted periplasmic protein
-------------------------------------------------|--|------||-||--  1 [K] COG3905 Predicted transcriptional regulator
---------------------------------------------|---|--|-------------  1 [R] COG3907 PAP2 (acid phosphatase) superfamily protein
-------------------------------------------------|---||----||-|---  1 [C] COG3909 Cytochrome c556
-------------------------------------------------|-----|---|--|---  1 [S] COG3913 Uncharacterized protein conserved in bacteria
------------------------------------------------||---------|------  1 [S] COG3915 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|---|---|--  1 [Q] COG3917 2-hydroxychromene-2-carboxylate isomerase
----------------------------------------------|--|---------||||---  1 [S] COG3921 Uncharacterized protein conserved in bacteria
------------------------------------------------||---------||-----  1 [S] COG3930 Uncharacterized protein conserved in bacteria
-------------------------------------------------|---------||||---  1 [E] COG3931 Predicted N-formylglutamate amidohydrolase
--------------------------------------------||--|||---------------  1 [R] COG3941 Mu-like prophage protein
---------------------------------------------||--|---||-----------  1 [R] COG3943 Virulence protein
-------------------------------------------------|--|--|---|||----  1 [U] COG3946 Type IV secretory pathway, VirJ component
----------------------------------------------|--|--|--|----------  1 [R] COG3948 Phage-related baseplate assembly protein
------------------------|-----------------||||||||-----|----------  1 [MNO] COG3951 Rod binding protein
--------------|---||----------||-----------------|----------|||---  1 [G] COG3957 Phosphoketolase
------------------------------------------|||-|--|-----|----|-|---  1 [R] COG3960 Glyoxylate carboligase
-------------------------------||--|------|||-|--|-----|----------  1 [R] COG3969 Predicted phosphoadenosine phosphosulfate sulfotransferase
---------------------|-----||-------------|||||--|-|---|---|-|-|--  1 [Q] COG3971 2-keto-4-pentenoate hydratase
----------------------------------------------|--|--|------|------  1 [R] COG3972 Superfamily I DNA and RNA helicases
---|---------------------------|---|-|-------||-||----------------  1 [R] COG3979 Uncharacterized protein contain chitin-binding domain type 3
-------------------|----------|--|--------------||----------------  1 [P] COG4097 Predicted ferric reductase
----------------|-------------------------||||||||||||||||||||||||  1 [R] COG4105 DNA uptake lipoprotein
---------------------|-----||-------------||||---|---------||||---  1 [R] COG4106 Trans-aconitate methyltransferase
-------------------|----------------------||||---|---------||-|---  1 [P] COG4107 ABC-type phosphonate transport system, ATPase component
------------------||-|----|---||||||------||||||||||||||---|||||--  1 [J] COG4108 Peptide chain release factor RF-3
-------------------|----------------------|||-|--|-----|-----||---  1 [C] COG4117 Thiosulfate reductase cytochrome B subunit (membrane anchoring protein)
--------------------|-----|-----||--------------||-----|---||||-||  1 [R] COG4120 ABC-type uncharacterized transport system, permease component
||--------------|-||-|---|----------------|||||-||||---|--|||--|--  1 [S] COG4121 Uncharacterized conserved protein
---------------------------------------------|--||----------------  1 [R] COG4128 Zonula occludens toxin
-------------------------------------------------|--------|||||---  1 [R] COG4132 ABC-type uncharacterized transport system, permease component
------------------------------------------|||||-|||||------|||||||  1 [O] COG4133 ABC-type transport system involved in cytochrome c biogenesis, ATPase component
------------------------------------------|||||-||-|||||----------  1 [R] COG4137 ABC-type uncharacterized transport system, permease component
--------|-------|--|-|----|---------||----|||||-||--|--|----------  1 [R] COG4147 Predicted symporter
----------------------------------|-------|||||-||||-------||||---  1 [P] COG4148 ABC-type molybdate transport system, ATPase component
--|---------|---|-||------|||-----||||----|||||-||||---|||||||||--  1 [P] COG4149 ABC-type molybdate transport system, permease component
------------------------------------------|||||-||-----|---||-||--  1 [Q] COG4181 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component
------------------||-----------------|-----------|-----|---|---|--  1 [R] COG4188 Predicted dienelactone hydrolase
---|---------------------------------------------|----------|-----  1 [K] COG4190 Predicted transcriptional regulator
------------------------------------------|||||-||-----|-----|-|--  1 [H] COG4206 Outer membrane cobalamin receptor protein
------------------||-------||--------|----|||||-||--||||---|||||--  1 [P] COG4208 ABC-type sulfate transport system, permease component
---|---------||---||||----|||--|-|||------|||-|-||||||||||||||----  1 [R] COG4221 Short-chain alcohol dehydrogenase of unknown specificity
-------------||-|--------------------------------|--|-------------  1 [C] COG4229 Predicted enolase-phosphatase
------------------------------------------|||||--|-|-|||---|||||--  1 [C] COG4230 Delta 1-pyrroline-5-carboxylate dehydrogenase
------------------------------------------|||||--||||------|||||--  1 [O] COG4235 Cytochrome c biogenesis factor
----------------|-||-----------------------------|----------|-|---  1 [S] COG4244 Predicted membrane protein
------------------||-|---------------------------|---------|------  1 [T] COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase)
------------------||-|---------------------------|-----|----|--|--  1 [T] COG4252 Predicted transmembrane sensor domain
-------------------------------------------------|-----|----|--|--  1 [S] COG4254 Uncharacterized protein conserved in bacteria
------------------|------------------------------|-----|----------  1 [V] COG4257 Streptogramin lyase
---------------------------------------------|---|---|||----------  1 [S] COG4259 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|----||----  1 [C] COG4263 Nitrous oxide reductase
-------------||----------------------------------|-----|----|-----  1 [F] COG4266 Allantoicase
-----------------|--|---------|------------------|-----|----------  1 [S] COG4267 Predicted membrane protein
-------------------|-|------------|--------------|----------------  1 [S] COG4270 Predicted membrane protein
--|---|------------------------------------------|-----|----------  1 [S] COG4273 Uncharacterized conserved protein
-----------|-------|-----------------------------|-----|----------  1 [S] COG4278 Uncharacterized conserved protein
--------------------|---------|----|------|||-|--|-----|----------  1 [E] COG4302 Ethanolamine ammonia-lyase, small subunit
--------------------|---------|----|------|||-|--|-----|----------  1 [E] COG4303 Ethanolamine ammonia-lyase, large subunit
-------------------------------------------------|-----|---||||---  1 [E] COG4311 Sarcosine oxidase delta subunit
-------------------------------------------------|-----|---||-|---  1 [S] COG4312 Uncharacterized protein conserved in bacteria
-------------------------------------------------|---|||----||----  1 [C] COG4314 Predicted lipoprotein involved in nitrous oxide reduction
-------------------------------------------------|-----|---||-----  1 [S] COG4315 Uncharacterized protein conserved in bacteria
-------------------------------------|-----------|-----|---||-----  1 [S] COG4317 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|---|--|---  1 [S] COG4318 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|---||||---  1 [R] COG4321 Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis
-------------------------------------------------|-----|-------|--  1 [S] COG4323 Predicted membrane protein
-------------------------------------------------|-----|------|---  1 [R] COG4324 Predicted aminopeptidase
--------------|-----------|---------|------------|---------|------  1 [S] COG4336 Uncharacterized conserved protein
-------------------|-----------------------------|------------|---  1 [S] COG4339 Uncharacterized protein conserved in bacteria
-------------------|-----------------------------|-----|------|---  1 [R] COG4341 Predicted HD phosphohydrolase
---------------------------------------------|---|---|||----------  1 [S] COG4380 Uncharacterized protein conserved in bacteria
----------------------------------------------|--|--|--|---|------  1 [R] COG4385 Bacteriophage P2-related tail formation protein
---------------------|---------|-|||-|----------||-----|----------  1 [S] COG4392 Predicted membrane protein
--------------------|----------------------------|----||----------  1 [S] COG4394 Uncharacterized protein conserved in bacteria
------------------------------------------------||-----|---|||||||  1 [S] COG4395 Uncharacterized protein conserved in bacteria
----------------------------------|--|-------|---|----------------  1 [S] COG4408 Uncharacterized protein conserved in bacteria
----------------------------------|----------|---|-----------|----  1 [E] COG4413 Urea transporter
-------------------|--------------------------|-||----------------  1 [FJ] COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA
------------------||-----------------------------|-------------|--  1 [R] COG4447 Uncharacterized protein related to plant photosystem II stability/assembly factor
--------------------|---------------------|||||--|---------|------  1 [V] COG4452 Inner membrane protein involved in colicin E2 resistance
------------|------|----------------------------||---------||-|---  1 [P] COG4454 Uncharacterized copper-binding protein
---------------------------------------------||--|---------|------  1 [R] COG4455 Protein of avirulence locus involved in temperature-dependent protein secretion
------------------------------------------------||---------||-----  1 [C] COG4459 Periplasmic nitrate reductase system, NapE component
----------------------------------------------|--|------------|---  1 [S] COG4460 Uncharacterized protein conserved in bacteria
---------------------------||----------------||--|---------|--|---  1 [S] COG4461 Uncharacterized protein conserved in bacteria, putative lipoprotein
---------------------------------------------|---|--|-------------  1 [S] COG4517 Uncharacterized protein conserved in bacteria
---------------------------------------------|--||----------------  1 [S] COG4519 Uncharacterized protein conserved in bacteria
------------------------------------------||||---|----------|-|---  1 [P] COG4521 ABC-type taurine transport system, periplasmic component
------------------------------------------||||---|---------||-|---  1 [P] COG4525 ABC-type taurine transport system, ATPase component
------------------------------------------|||||-||||-------|||----  1 [P] COG4531 ABC-type Zn2+ transport system, periplasmic component/surface adhesin
------------------------------------------||||||||||||||----------  1 [P] COG4535 Putative Mg2+ and Co2+ transporter CorC
----------------------------------|-------|||||-||||---|----||||||  1 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB
-------------||----------------------------------|-----|----------  1 [S] COG4539 Predicted membrane protein
---------------------------------------------||--|--|--|----------  1 [R] COG4540 Phage P2 baseplate assembly protein gpV
----------------------------------|-|------------|---------|||----  1 [P] COG4548 Nitric oxide reductase activation protein
-------------------|-----------------------------|-----|------|---  1 [R] COG4551 Predicted protein tyrosine phosphatase
---------------------|----|----------------|||--||-|-------||-|---  1 [P] COG4558 ABC-type hemin transport system, periplasmic component
---------------------|----|----------------|||--||---------||-|---  1 [P] COG4559 ABC-type hemin transport system, ATPase component
----------------------------------------------|--|-|---|---|||||--  1 [T] COG4566 Response regulator
-------------------------------------------------|--|--|---|||||--  1 [TK] COG4567 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
------------------------------------------|||||-||----------------  1 [K] COG4568 Transcriptional antiterminator
------------------------------------------|||||--|---------------|  1 [R] COG4574 Serine protease inhibitor ecotin
------------------------------------------|||||--|-----|----------  1 [T] COG4579 Isocitrate dehydrogenase kinase/phosphatase
-------------------------------------------------|-----|---||||---  1 [E] COG4583 Sarcosine oxidase gamma subunit
--------------------|---------------------||||--||-|--------|-----  1 [R] COG4589 Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase
---------------------------------------------|--||----------------  1 [R] COG4590 ABC-type uncharacterized transport system, permease component
------------------------------------------|||||-||----------------  1 [P] COG4592 ABC-type Fe2+-enterobactin transport system, periplasmic component
---|--|||-|-|----|-|-|--||----||||-||-||||-------|-----|---||||---  1 [R] COG4603 ABC-type uncharacterized transport system, permease component
--|||||||-|||---||--||||-||---||||||||-||||||||-||||---||||||||---  1 [E] COG4608 ABC-type oligopeptide transport system, ATPase component
------------------------------------------|||-|--|-----|--|-------  1 [QP] COG4615 ABC-type siderophore export system, fused ATPase and permease components
--------------------|----------------------------|--|--|---|--|---  1 [S] COG4625 Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain
---------------------|---------------------------|-----|---||||---  1 [F] COG4630 Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A
---------------------|---------------------------|-----|---|||||--  1 [F] COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B
-------------------|-----------------------------|----------|-----  1 [R] COG4637 Predicted ATPase
------------------|-------------||---------------|---||-------|---  1 [S] COG4642 Uncharacterized protein conserved in bacteria
------------------------------------------|||-|--|-----|----------  1 [KT] COG4650 Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain
------------------------------------------|||||-||--|--|----|||---  1 [P] COG4651 Kef-type K+ transport system, predicted NAD-binding component
----------------|--------------------------------|-----|----------  1 [C] COG4654 Cytochrome c551/c552
-------------------------------------------------|-----|---||-|---  1 [S] COG4655 Predicted membrane protein
--|--------------|--|---||---------|------||||||||||--------------  1 [C] COG4656 Predicted NADH:ubiquinone oxidoreductase, subunit RnfC
--|--------------|--|---------------------||||||||||--------------  1 [C] COG4657 Predicted NADH:ubiquinone oxidoreductase, subunit RnfA
--|--------------|--|---|-----------------||||||||||--------------  1 [C] COG4658 Predicted NADH:ubiquinone oxidoreductase, subunit RnfD
--|--------------|--|---------------------||||||||||--------------  1 [C] COG4659 Predicted NADH:ubiquinone oxidoreductase, subunit RnfG
--|--------------|--|---------------------||||||||||--------------  1 [C] COG4660 Predicted NADH:ubiquinone oxidoreductase, subunit RnfE
---|----|---|--------|---------------|----------||-|--------||----  1 [R] COG4666 TRAP-type uncharacterized transport system, fused permease components
---------------------|--------||-|||||--|-||||||||||---|----------  1 [G] COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain
----------------------||-------------------||||--|-----|------|---  1 [U] COG4669 Type III secretory pathway, lipoprotein EscJ
-------------------------------------------||||--|-----|----------  1 [S] COG4672 Phage-related protein
------------------||-|----|----------|-------|---|-----|---||-|---  1 [R] COG4674 Uncharacterized ABC-type transport system, ATPase component
------------------------------------------|||||--|-----|----------  1 [S] COG4681 Uncharacterized protein conserved in bacteria
------------------------------------------|||----|-----|----------  1 [S] COG4685 Uncharacterized protein conserved in bacteria
--|----------------------------||-------------|--|----------------  1 [E] COG4690 Dipeptidase
---------------------------------------------|---|-----|----------  1 [Q] COG4693 Oxidoreductase (NAD-binding), involved in siderophore biosynthesis
-------------------------------------------||||--|-----|----------  1 [S] COG4718 Phage-related protein
-------------------------------------------||||--|-----|----------  1 [S] COG4723 Phage-related protein, tail component
-------------------------------------------------|--||||----------  1 [NU] COG4726 Tfp pilus assembly protein PilX
------------------------------|------------------|-----|----------  1 [S] COG4728 Uncharacterized protein conserved in bacteria
---|----|----------------------------|-----------|-|--------------  1 [S] COG4729 Uncharacterized conserved protein
-------------------------------------------||||--|-----|----------  1 [S] COG4733 Phage-related protein, tail component
|-|------|---------------------------------------|----------------  1 [S] COG4744 Uncharacterized conserved protein
-------------------------------------------------|---------||||---  1 [S] COG4764 Uncharacterized protein conserved in bacteria
-------------||-||||||||||----------------||||||||||||||||||||||||  1 [M] COG4775 Outer membrane protein/protective antigen OMA87
-------------------|----------------------||||---|---------||-|---  1 [P] COG4778 ABC-type phosphonate transport system, ATPase component
--------------------------|---------------|||||-||---------|------  1 [P] COG4779 ABC-type enterobactin transport system, permease component
----------------|-||----------------------|||||-||--|--|-----|||--  1 [R] COG4783 Putative Zn-dependent protease, contains TPR repeats
-------------------------------------------------|---------||||---  1 [R] COG4784 Putative Zn-dependent protease
----------------||------||----|----|||----||||||||-----|||||||||--  1 [N] COG4786 Flagellar basal body rod protein
------------------------------------------||||||||-----|----------  1 [N] COG4787 Flagellar basal body rod protein
----------------------||-------------------||||--|-----|------|---  1 [U] COG4789 Type III secretory pathway, component EscV
-------------------------------------------||||--|-----|------|---  1 [U] COG4790 Type III secretory pathway, component EscR
----------------------||-------------------||||--|-----|------|---  1 [U] COG4791 Type III secretory pathway, component EscT
-------------------------------------------||||--|------------|---  1 [U] COG4792 Type III secretory pathway, component EscU
----------------------||-------------------||||--|-----|------|---  1 [U] COG4794 Type III secretory pathway, component EscS
----------------||||----------------------|||||-||||||||----------  1 [U] COG4796 Type II secretory pathway, component HofQ
--------------------|---------------------|||||--|----------------  1 [S] COG4807 Uncharacterized protein conserved in bacteria
--------------------------|||--------------------|----------------  1 [Q] COG4829 Muconolactone delta-isomerase
--------------------|----------------------------|---||-----------  1 [S] COG4859 Uncharacterized protein conserved in bacteria
--|----------|||---|----------|-|--|------|||||--|-----|----------  1 [S] COG4886 Leucine-rich repeat (LRR) protein
----------------------------------------------|--|-----------|----  1 [S] COG4893 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|----|-||--  1 [K] COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain
--------------------|---------------------|||||-|||||||----|||||--  1 [D] COG4942 Membrane-bound metallopeptidase
------------------------------------------|||-|--|--|--------|----  1 [T] COG4943 Predicted signal transduction protein containing sensor and EAL domains
---------------------------------------------|---|-|---|---||-||--  1 [OU] COG4960 Flp pilus assembly protein, protease CpaA
---------------------------------------------|---|-|---|---||-||--  1 [U] COG4961 Flp pilus assembly protein TadG
||----||-|----------------|||-|--------------|---|-||--|---||-||--  1 [U] COG4962 Flp pilus assembly protein, ATPase CpaF
---------------------------------------------|---|-|---|---||-||--  1 [U] COG4963 Flp pilus assembly protein, ATPase CpaE
---------------------|---------------------------|-|---|---||-||--  1 [U] COG4964 Flp pilus assembly protein, secretin CpaC
--------------------------|||----------------|---|-|---|---||-||--  1 [U] COG4965 Flp pilus assembly protein TadB
-------------------------------------------------|--||||----------  1 [NU] COG4966 Tfp pilus assembly protein PilW
------------------------------------------|||||-||--||||----------  1 [NU] COG4967 Tfp pilus assembly protein PilV
------------------------------------------------||--||||----------  1 [NU] COG4968 Tfp pilus assembly protein PilE
------------------||-|--------------------------||--||||----------  1 [NU] COG4972 Tfp pilus assembly protein, ATPase PilM
------------------------------------------|||||-||||||||----------  1 [L] COG4973 Site-specific recombinase XerC
--------------------|---|-|||||---||||----|||||-||||||||---|||||||  1 [L] COG4974 Site-specific recombinase XerD
---------------------------------------------|--||----------------  1 [P] COG4985 ABC-type phosphate transport system, auxiliary component
----------------------------------------------|--|--|--|----------  1 [R] COG5004 P2-like prophage tail protein X
---------------------|----|---------------|||||-||-----|------||--  1 [R] COG5006 Predicted permease, DMT superfamily
------------------------------------------||||||||||||||----------  1 [K] COG5007 Predicted transcriptional regulator, BolA superfamily
------------------------------------------------||--||||----------  1 [NU] COG5008 Tfp pilus assembly protein, ATPase PilU
----------------|-------||----------------|||||-||||||||---|||||||  1 [M] COG5009 Membrane carboxypeptidase/penicillin-binding protein
---------------------------------------------|---|-|---|---||-||--  1 [U] COG5010 Flp pilus assembly protein TadD, contains TPR repeats
----------|-|-------------|||-----|-|-----|||-|--|-----|-----|----  1 [C] COG5013 Nitrate reductase alpha subunit
|||---|-|-------||--|---|-------|-------------|-||-|------|-------  1 [C] COG5016 Pyruvate/oxaloacetate carboxyltransferase
--------------|---------------------|------------|----------------  1 [R] COG5018 Inhibitor of the KinA pathway to sporulation, predicted exonuclease
-------------------------------------------||||--|-----|---|-|----  1 [S] COG5281 Phage-related minor tail protein
----------------------------------------------|--|-----|----------  1 [R] COG5301 Phage-related tail fibre protein
-||---||-----------------------------------------|----------------  1 [S] COG5306 Uncharacterized conserved protein
-------------||----------------------------------|----------------  1 [G] COG5309 Exo-beta-1,3-glucanase
-------------------------------------------------|---------||||---  1 [S] COG5345 Uncharacterized protein conserved in bacteria
-------------------------------------------------|---------|--|---  1 [S] COG5351 Uncharacterized protein conserved in bacteria
---------------------------------------------|---|-----|---||-|---  1 [S] COG5373 Predicted membrane protein
------------------------------------------------||--|-------------  1 [O] COG5380 Lipase chaperone
------------------------------------------|||||--|-----|----------  1 [S] COG5393 Predicted membrane protein
------------------------------------------|||||--|----------------  1 [D] COG5404 SOS-response cell division inhibitor, blocks FtsZ ring formation
----------------||-------|--------||||----|||||||||||--|||||||||||  1 [O] COG5405 ATP-dependent protease HslVU (ClpYQ), peptidase subunit
-------------------------------------------||||--|-----|----------  1 [S] COG5435 Uncharacterized conserved protein
------------------------------------------|||----|-----|----------  1 [S] COG5445 Predicted secreted protein
-------------------------------------------------|---------|-||---  1 [S] COG5446 Predicted integral membrane protein
-------------||----------------------------------|---------||-|---  1 [S] COG5478 Predicted small integral membrane protein
-------------------|-----------------------------|-----|---||-|---  1 [R] COG5485 Predicted ester cyclase
-------------------------------------------|-||--|-----|---||||---  1 [S] COG5487 Small integral membrane protein
--|---------------------------|------------------|----------------  1 [S] COG5513 Predicted secreted protein
-------------------------------------------------|----------|--|--  1 [S] COG5528 Predicted integral membrane protein
------------------------------------------|||||--|-----|----------  1 [R] COG5544 Predicted periplasmic lipoprotein
-------------------|-----------------------------|------------|---  1 [R] COG5553 Predicted metal-dependent enzyme of the double-stranded beta helix superfamily
------------------------------------------||-||--|-----------|----  1 [N] COG5567 Predicted small periplasmic lipoprotein
------------------------------------------|||-|--|-||-------------  1 [N] COG5571 Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion
-----------------|------------|-----||----|||||--|----------------  1 [M] COG5581 Predicted glycosyltransferase
------------------------------|-----||-----------|----------------  1 [S] COG5583 Uncharacterized small protein
--|--------|------||-----------------------------|-----|----|-----  1 [S] COG5607 Uncharacterized conserved protein
------|||----------------------------------------|----------------  1 [S] COG5608 Conserved secreted protein
-------------------------------------------||||--|----------------  1 [S] COG5613 Uncharacterized conserved protein
----||------|------------------------------------|----------------  1 [S] COG5615 Predicted integral membrane protein
-------------------------------------------------|--|------|------  1 [S] COG5619 Uncharacterized conserved protein
------------------||-----------------------------|----------------  1 [S] COG5626 Uncharacterized conserved small protein
------------------------------------------|||||--|||--------------  1 [R] COG5645 Predicted periplasmic lipoprotein