| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ ||||||||||||||||||||||||||||||||||||||-||||||||||||||||||||||||||| 23 [GEPR] COG0477 Permeases of the major facilitator superfamily |-|-------|-----||-|||--|-|||-||||||||----|||||-||||||||---||||||| 21 [K] COG1396 Predicted transcriptional regulators |||||||||-||||||||||||||--|||||||||||||---|||||-||||||||||||||||-| 19 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases --------------------|-|||||---||||||||-||||||||-||||-|||---|||||-- 19 [GT] COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) |-||||||||||||||-|||-|---||||||||||||||||-|||||-||-|||||||-|||||-- 15 [V] COG1131 ABC-type multidrug transport system, ATPase component |||||||||||||----|-|||----||||||||||||----|||||-||--||||---|||||-- 14 [K] COG1846 Transcriptional regulators -------------||||||||||||-|||||||-||||----|||||-||||||||--||||||-- 13 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases |-||||||||||||||-||||||||||||||||||||||||||||||||-||-|||---||-|--- 12 [R] COG0561 Predicted hydrolases of the HAD superfamily |-||---||--|----||||||----|||||||||||||---|||||-||||||||--||||||-- 12 [K] COG1309 Transcriptional regulator --------------------|-----|---||||||||----|||||------------------- 12 [K] COG3711 Transcriptional antiterminator --||--||--||-|||||||||||--|||||||||||||||||||||||||||||||||||||||| 11 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components ||||----|||||---|||||||||||||-|||||||||||||||||||||||||||||||||||| 11 [V] COG1136 ABC-type antimicrobial peptide transport system, ATPase component ----------------||||||||--||||||||||||----|||||-|||||||||||||||||| 10 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain --|-----|-------|-||||----||||||||||||----|||||-|||||||||||||||||| 10 [K] COG0789 Predicted transcriptional regulators -------------------------|----||||-|||----|||||-|----------------- 10 [G] COG1440 Phosphotransferase system cellobiose-specific component IIB -------------------------|----||||||||----|||||-|----------------- 10 [G] COG1455 Phosphotransferase system cellobiose-specific component IIC -----------------|--||----|||-||||||||-|--|||||-|||||--|---|||||-- 10 [K] COG1609 Transcriptional regulators -|-|----|-------|---------|-------||---------|------|--------|||-- 10 [L] COG3316 Transposase and inactivated derivatives --|----------|||---|----------|-|--|------|||||--|-----|---------- 10 [S] COG4886 Leucine-rich repeat (LRR) protein |||||||||--||---||||||||--||||||||||||||--|||||-|||||||||||||||||| 9 [L] COG0582 Integrase ----||||--||--------------|---||||||||----|||||-|----------||--|-- 9 [G] COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase |-||--|||--||||---||||----||||||||||||----|||||-||||||||--||||||-- 8 [E] COG0346 Lactoylglutathione lyase and related lyases ||||----||||-----||||||||-|||-||||||||----|||||-||-|-|||--||||||-- 8 [V] COG0577 ABC-type antimicrobial peptide transport system, permease component ||------||------|-||||----||||||||||||----|||||-||||||||--||||||-- 8 [K] COG0583 Transcriptional regulator |-||||||-|||-||-||||-|----|---||||||||----|||||-||-|---|||||||||-- 8 [R] COG0673 Predicted dehydrogenases and related proteins --|||||||-||||||||||||||--||||||||||||----|||||||||||||||||||||||| 8 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) -------------------------|----||||||||----|||||-|----------------- 8 [G] COG1447 Phosphotransferase system cellobiose-specific component IIA ---|||--|-|-|---||||||---|||||||||||||-|--|||||-|-||-------|||||-- 8 [KG] COG1940 Transcriptional regulator/sugar kinase -------------------|-|----|||-||||||||||--|||||-||-----|---|||||-- 8 [K] COG2188 Transcriptional regulators --|-||-----|-||-||||||----||||||||||||----|||||-||-||--|---|||||-- 7 [G] COG0406 Fructose-2,6-bisphosphatase |||||||||||||||||||||||||-||||||||||||----|||||||||||||||||||||||| 7 [QR] COG0500 SAM-dependent methyltransferases |-||----|----||-||||||||-|||||||||||||----|||||-|||||||||||||||||| 7 [T] COG0642 Signal transduction histidine kinase -----------------||||||||--||-|---||||----------||---------||--|-- 7 [T] COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) ----------------|----|||-||||-||--||||-------|--||||-------------- 7 [M] COG1388 FOG: LysM repeat -----------------||||-----|||-||-|||||----|||||-||||||||--||||||-- 7 [K] COG2207 AraC-type DNA-binding domain-containing proteins ------------------|||--------------|------|||-|------------------- 7 [QC] COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein ---|||||--|||----|||-|--|-||||||||-|||-||||||||-||-||--|---||||--- 6 [G] COG0395 ABC-type sugar transport system, permease component |||||||||--|-|||||||||||||----||||||||----|||||-||-||||||||||||||| 6 [R] COG0457 FOG: TPR repeat |-||||--|-|||||||||||||||-||||||||||||----|||||||||||||||||||||||| 6 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes |||||||||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||| 6 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins ||||--|||---|||-|||-||--|||||-|||||||||||||||||-||||||||||||||||-- 6 [V] COG0534 Na+-driven multidrug efflux pump ----------------||||||||||||||||||||||----|||||||||||||||||||||||| 6 [D] COG0772 Bacterial cell division membrane protein ---|||||--|||----|||-|--|-||||||||||||-||||||||-||-||--|---||||--- 6 [G] COG1175 ABC-type sugar transport systems, permease components ----------------||--||----|---||||||||----|||||-||||-|||---||||--- 6 [KG] COG1349 Transcriptional regulators of sugar metabolism ---|||||--|||----|||-|--|-||||||||-|||----|||||-||-||--|---||||--- 6 [G] COG1653 ABC-type sugar transport system, periplasmic component -|||||-|-----||--|-|||----||||||||||||--|-|||||-||-|-||||||||||||| 6 [J] COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins -----------------|-------------||-|||-----|||||-||-----|-----|---- 6 [NU] COG1705 Muramidase (flagellum-specific) ----------------------------------|||----------------------------- 6 [M] COG5632 N-acetylmuramoyl-L-alanine amidase -|--||-------||||||||||||-||||||||||||||||||||||||||||||||||||||-- 5 [G] COG0036 Pentose-5-phosphate-3-epimerase --|-||----|--||--|||-|----|||-||||||||-|--|||||-||-----|---||-||-- 5 [G] COG0366 Glycosidases ||||||||||||||||||||||---||||||||||||||||||||||-|||||||||||||||||| 5 [M] COG0463 Glycosyltransferases involved in cell wall biogenesis -------------|||--||||||||||||||||||||-|--|||||||||||||||||||||||| 5 [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains |||||||||||||||-||||||||-|||||||||||||----|||||-|||||||||||||||||| 5 [R] COG0517 FOG: CBS domain --||||--|-|||||||-||||---|||||||-||||||||||||||-|||||||||||||||||| 5 [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) -||||||||-|||----|||||----||||||||||||----|||||-||||---|||||||||-- 5 [P] COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component |||||||||||||---||||||----|||||||-||||----|||||-||-|||||--||||||-- 5 [K] COG0640 Predicted transcriptional regulators --|-----|-|-|----|||||||--|---||||||||----|||||-|||--||||||||||||| 5 [E] COG0765 ABC-type amino acid transport system, permease component |||||--||||||---||||||----||||||||||||----|||||-||||||||||||||||-- 5 [C] COG0778 Nitroreductase ------------------||-|||--||||||---|||----|||||-||||||||||||||||-- 5 [M] COG0791 Cell wall-associated hydrolases (invasion-associated proteins) ||||||---||||||-|-||||----|||||||||||||---|||||-||-|-|||||||||||-| 5 [C] COG1012 NAD-dependent aldehyde dehydrogenases --|||||||--||||--|-|-|-----||-||||||||--|-|||||-|||-||||---||-||-- 5 [ER] COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases ---------|-------|--|-||-|----||||||||||||------|----------|||---- 5 [S] COG1284 Uncharacterized conserved protein --------------------||---||---||||||||-||||||||-|||----|---------- 5 [G] COG1299 Phosphotransferase system, fructose-specific IIC component ||-|--|||-|||---|--|-|||||||||||||||||----|||||-||--|||||||||||||| 5 [K] COG1475 Predicted transcriptional regulators |-|||||||-|||----|-|||----||||||||||||----|||||-|------|------||-- 5 [K] COG1695 Predicted transcriptional regulators ----|------|-----|--||----|||-|||-||||----|||||-||---|||---|||||-- 5 [K] COG1802 Transcriptional regulators -----||---|-------||-|----|||-|-||||||----|||||-||--|--|---|||||-- 5 [L] COG1961 Site-specific recombinases, DNA invertase Pin homologs -----------------------------------||-----|||||-||||-------------- 5 [T] COG3103 SH3 domain protein -------------------------------|---|-|---------------------------- 5 [M] COG4932 Predicted outer membrane protein ||||||--|||||||-||||||||-|||||||||||||-||||||||-|-|||--|--|||||||| 4 [C] COG0039 Malate/lactate dehydrogenases -|--||-------||-||||-|||--|||||-||||||----||||||||||-|||||||||||-- 4 [G] COG0176 Transaldolase -------------||-||||-|--||||||||||||||||||||||||||||-||||||-||||-- 4 [G] COG0191 Fructose/tagatose bisphosphate aldolase -------------|||-||||-||||||||||||||||-|--|||||-||||||||||-|||||-- 4 [G] COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase -----||----|-||--|||-------||--|||-|-|----|----------------------- 4 [G] COG0383 Alpha-mannosidase |||||||||||||||-|||||||||-||||||||||||----|||||-|||||||||||||||||| 4 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase |||||||||||||||-||||||--|||||-||||||-|-||||||||-||-|---|---|||||-- 4 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases |||-||--|--|-||||-||||--|-||||||||||||||||||||||||||||||||-||||||| 4 [LKJ] COG0513 Superfamily II DNA and RNA helicases ||-|||||-|--|||-||||||-|-|||||||||||||----||||||||||||||||||||||-- 4 [F] COG0516 IMP dehydrogenase/GMP reductase ||||||--||||||||--|||-||--|||||||||||||||||||||-|||||--|---||||||| 4 [E] COG0531 Amino acid transporters -||||||||-|||----|||||----|---|||||||||---|||||-||||---|||||||||-- 4 [P] COG0609 ABC-type Fe3+-siderophore transport system, permease component ||||--|||-------||||||--|||||-||||||||----|||||||||||||||||||||||| 4 [R] COG0628 Predicted permease -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 4 [L] COG0629 Single-stranded DNA-binding protein ---|||||--||||||-||-------||||||||||||----|||||--|-----|---|||||-- 4 [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase ----------------|||-|-----|||||-|||||||||||--||----|----|||-|||-|| 4 [G] COG0698 Ribose 5-phosphate isomerase RpiB --|-----|-|-|----||||||||-||||||||||||----|||||-||||-||||||||||||| 4 [ET] COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain |-||||||||||||||-|||-|----||||||||||||----|||||-||-||--|||-|||||-- 4 [V] COG0842 ABC-type multidrug transport system, permease component |||---||||-|-----|||------|||||-|-||||----|||||--|-----|---|||||-- 4 [G] COG1082 Sugar phosphate isomerases/epimerases |||||||||||||||||||||||||||||||||||||||-|||||||||||||||||||||||||| 4 [G] COG1109 Phosphomannomutase --|-----|-|-|----|||||||--|---||||||||----|||||-|||--||||||||||||| 4 [E] COG1126 ABC-type polar amino acid transport system, ATPase component ||||||--|||||||-||||||||--||||-|||||||-|||||||||||||||||---||||||| 4 [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes --------------------||---||---||||||||-||||||||-||||---|---------- 4 [G] COG1445 Phosphotransferase system fructose-specific component IIB --||||||---|-----|||||----|||-||-|||||----|||----|||---|--||||||-- 4 [R] COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase --|-------------|----------||-|||||||||---||||||-------|---||-|--- 4 [L] COG1484 DNA replication protein ----||----||-||--|-|----------||-|-|-|----|||||--------|---|---|-- 4 [G] COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases ----|------|-----|||------|||-|-||||||---------------------------- 4 [K] COG1725 Predicted transcriptional regulators -----------------|--------|---||||||||-|--|||||-||||-|||---|||||-- 4 [K] COG1737 Transcriptional regulators ----------------||||||-----||-||-|||||----|||||-||||||||--|||||||| 4 [K] COG1959 Predicted transcriptional regulator ----------------||||-|--|-|||||---||||----|||||-||--|--|---|||||-- 4 [T] COG2199 FOG: GGDEF domain |-||||-||-|||||-|||||||||-|||||||||||||---|||||-||||-|||||||||||-- 4 [P] COG2217 Cation transport ATPase -------------||-----||---------|--||-|----||||-----|-------||||--- 4 [G] COG2376 Dihydroxyacetone kinase --------------------||----|||||---||||----|---|-||--|-||--||||||-- 4 [K] COG2378 Predicted transcriptional regulator -------------------|------|||-||--||-|----|||-|--|-----|----|-||-- 4 [S] COG2764 Uncharacterized protein conserved in bacteria --------------------|---------||||-||-----|||||----|||||---|||||-- 4 [G] COG2893 Phosphotransferase system, mannose/fructose-specific component IIA -----|--------------||----|||--|||||-|----|||||-|||----|---|||||-- 4 [L] COG2963 Transposase and inactivated derivatives --------------------------|---|-||||-|-||-|||-|-|--|-------------- 4 [G] COG3414 Phosphotransferase system, galactitol-specific IIB component --------------------|---------||||-||-----|||||----|-------------- 4 [G] COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB -------------------------------||-|||------|||-------------------- 4 [S] COG3645 Uncharacterized phage-encoded protein --------------------|---------||||-||-----|||||----|-------------- 4 [G] COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC --------------------|---------||||-||-----|||||----|-------------- 4 [G] COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID -----------------|--|-|||||||-||-||||-||--|||||-||||---|||-||||--- 4 [E] COG4166 ABC-type oligopeptide transport system, periplasmic component --------------------------|---||-|-|-|---------------------------- 4 [V] COG4767 Glycopeptide antibiotics resistance protein -------------|||||||-||||-||||||||||||||||||||||||||||||||||||||-- 3 [G] COG0021 Transketolase |||-||-||||||||-||||-|----||||||-|||||----||||||||||||||--||||||-- 3 [EH] COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] ||||---||||||||-||||||---||||-||||||||----|||||-||-|---|--|||||||| 3 [P] COG0053 Predicted Co/Zn/Cd cation transporters |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 3 [R] COG0073 EMAP domain ---|||||---||||-||||--||--|----|||||||-||||||||-||---------------- 3 [H] COG0095 Lipoate-protein ligase A ||||---|-||--||--|||-|||--||||||||||||----|||-|-||-|-|||--||||||-| 3 [R] COG0110 Acetyltransferase (isoleucine patch superfamily) ||||----|||--||-||||||----||||||||||||----|||||-|||||||||||||||||| 3 [EH] COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase ||||||||||||||||||||||||||||||||||||||----|||||||||||||||||||||||| 3 [H] COG0142 Geranylgeranyl pyrophosphate synthase ||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||-- 3 [E] COG0169 Shikimate 5-dehydrogenase |-||------------|||||||||||||||||||||||||||||||-|||||||||||||||||| 3 [L] COG0178 Excinuclease ATPase subunit ||||---||----------|-------||--|||||--|||-|||-|-|||||||||||-||-|-| 3 [V] COG0286 Type I restriction-modification system methyltransferase subunit --|----|---|-|||---||-----||||||||||||-----------|-|---|---||-||-- 3 [R] COG0300 Short-chain dehydrogenases of various substrate specificities ||||||||||||||--||-||-|||-||||||-|||||-|--|||||-||||||||||||||||-| 3 [L] COG0350 Methylated DNA-protein cysteine methyltransferase --||-------|-||---|||-----|||-|||||||||||||||||-||-|-|||---|||||-- 3 [L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair |-||----|----||-|-||-|----|||-||||||||----|||-|-||-|||||--||||||-- 3 [T] COG0394 Protein-tyrosine-phosphatase ||||||||-||||||||||||||||-||||||||||||----||||||||||||||||||||||-- 3 [M] COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains ||||||||||||||||||||||----|||||||||||||---|||||-||||||||--||||||-- 3 [R] COG0456 Acetyltransferases ||----||-|||-||-||||||||||||||||||||||----|||||||||||||||||||||-|| 3 [M] COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase |||-|--------||||-|||-----||||||||-||||||||||||--|----------|||--- 3 [P] COG0474 Cation transport ATPase ||||||||||||||||||||||----||||||||||||----||||||||||||||||||||||-- 3 [R] COG0491 Zn-dependent hydrolases, including glyoxylases ||||||||||||||-||||||||||||||||||||||||||||||||||||||||||||||||||| 3 [O] COG0492 Thioredoxin reductase ||||--||-||||||--|||||--|||||-||||||||||||||||||||||-||||||||||--- 3 [F] COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins |||||-|||||||||-||||-|||--||||||-|||||----|||||||||||||||||||||||| 3 [E] COG0527 Aspartokinases |------------||||||||||||||||||||||||||-|||||||-|||||||||||||||||| 3 [O] COG0542 ATPases with chaperone activity, ATP-binding subunit --||-||||--|||||-|||||||--|||-||||-|||--|||||||-|||||-------|----- 3 [KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family --||--|||----||||||||||||||||||||||||||||||||||||||||||||||||||||| 3 [F] COG0563 Adenylate kinase and related kinases -------------||||||||||||||||||||||||||||||||||||||||||||||||||||| 3 [J] COG0564 Pseudouridylate synthases, 23S RNA-specific ----||-----|------||-|--||||||||--||||----|||||||||||||||||--|||-- 3 [S] COG0586 Uncharacterized membrane-associated protein |||||||||||||-|-|-||-|----||||-|||||||----|||||-||||-|||---||||||| 3 [T] COG0589 Universal stress protein UspA and related nucleotide-binding proteins -||---|-|-||-||-||||||----|||||||||||-----|||||-|||||--|||||||||-| 3 [P] COG0598 Mg2+ and Co2+ transporters --|||||||-|||---||||||||-||||||||||||||||||||||-||||---||||||||--- 3 [EP] COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components --||||----||-||-|--|-|----||||-|--||||----|||||-||-||--|---|||||-- 3 [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases |-||||--|-||-||||-||||---|||||||||||||----|||||||||||||||||||-|||| 3 [P] COG0607 Rhodanese-related sulfurtransferase ||||--||||-||----|||||----||||||||||||||||-||-|---|--------|||---- 3 [P] COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters -|--|||||||||||-||--||-|--||||||||||||----|||||||||||||||||||||||| 3 [E] COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases --|-|||---||-||--|||-|||--|||||||-||||-|--|||||-||||||||---|||||-- 3 [R] COG0637 Predicted phosphatase/phosphohexomutase ||||||||||||||||||||||||||||||||||||||-|--|||||||||||||||||||||||| 3 [U] COG0681 Signal peptidase I --|-||--|-|||---||||||---||||||||-||||--|||||||-||||||||||||||||-- 3 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins ----------------||||||||||||||||||||||----|||||||||||||||||||||||| 3 [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2 |-||--|||-|-|---|||||||||-||||||||||||-------||--|||-||---|||-|-|| 3 [P] COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin ----------------|-|||||||||||||---||||----||||||||||||||||||||||-- 3 [M] COG0860 N-acetylmuramoyl-L-alanine amidase --||---||---||||-|-|||||--|||-|||--|||----|||||-||-||--|---|||||-- 3 [R] COG1073 Hydrolases of the alpha/beta superfamily |---||--||------||-||-||||----|----|||----|||||-|||||--||||----||| 3 [D] COG1077 Actin-like ATPase involved in cell morphogenesis --|-----|----||||||||||||-||||||||||||----||||||||||-||||||||||||| 3 [E] COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes |-||--|||-|-|---|||||||||-||-|||||||||----||||||||||-||---|||||-|| 3 [P] COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components -||||||||--||----|||||----|---|-|||||||-|||||||-||||---|||||||||-- 3 [PH] COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components |-||--|||-|||---|||||||||-|--|||||||||----||||||||||-||---|||||-|| 3 [P] COG1121 ABC-type Mn/Zn transport systems, ATPase component ||||--|||||||----|||||--|-||||||||||||||||-||-|-|-|----|---|||---- 3 [P] COG1122 ABC-type cobalt transport system, ATPase component --|||||||-|||---||||||||-||||||||||||||||||||||-||||---||-|||||--- 3 [EP] COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components --------|----------|||-----||-|||||||-----|||||--|-----|||-||||--- 3 [E] COG1174 ABC-type proline/glycine betaine transport systems, permease component ||||||||||----|-|-|||-||||----||||||||----||||---|-----|---||||||| 3 [R] COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I --||---------||-|||||||||||||-|||||||-|||||||||||||||||||||||||||| 3 [R] COG1253 Hemolysins and related proteins containing CBS domains |-||--||--|-|---|||||||||||||-||||||||-----||||-||-----|------||-- 3 [R] COG1266 Predicted metal-dependent membrane protease --|||||||--||----|||-|--||----|---|||||||--------|-----|----||---- 3 [R] COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component ---|------------||--||----|||||||-||||----||||||||||||||---||||||| 3 [K] COG1278 Cold shock proteins -----------------|--||----|||-||||||||||||-------|---------------- 3 [S] COG1307 Uncharacterized protein conserved in bacteria -----------------|||-|--||||||||||||||---------------------------- 3 [K] COG1316 Transcriptional regulator --||--------------|-||----|||-||-|-||-----|||||-||-|-|||---||-||-- 3 [S] COG1359 Uncharacterized conserved protein ||||--|||||-|----|-|||--------||||||||||--|||-|--|----------|----- 3 [G] COG1363 Cellulase M and related proteins |-|||||||--||||-||--|-----|---||-|||||----|||||-||-|---|---||||--- 3 [C] COG1454 Alcohol dehydrogenase, class IV -----------------|------------|----|||----|||||-|----------||-|--- 3 [G] COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases |--------------------|----||||||||||||---------------------------- 3 [S] COG1511 Predicted membrane protein -----------------|||||--|-||||||--||||----|||||-||||||||---|||||-- 3 [K] COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog ----|--------||--|||-|----|||-||||||||----|||||--|---------||-||-- 3 [IR] COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase -----------------|------|---------||||---------------------------- 3 [R] COG1647 Esterase/lipase -------------------|-||||||||||||||||||---|||||-|||||||||||||||||| 3 [D] COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins --|---||--|-|-----||-|----||||||||||||----|||||--|--|--|---||||||| 3 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins --|---|||||||---|||||||||||||-||--||||----|||||-|||||------|||||-| 3 [R] COG1694 Predicted pyrophosphatase ||||||--|--||-----||||----|||-||--||||----|||||-||-||--|--|||-||-- 3 [K] COG1733 Predicted transcriptional regulators ----------------||----||||----|----|||----||||||||-----|||||||||-- 3 [NU] COG1886 Flagellar motor switch/type III secretory pathway protein |-----|------------------------|--|||------------|--|------------- 3 [M] COG1887 Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC --||||--|--|-||--|-|||----|||-|||-||||-|--|||||-||--|--|---|||||-- 3 [C] COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family ----------------|-||-|---||||||----|||----|||||-||--|--|---||||||| 3 [T] COG2200 FOG: EAL domain ||||||||||-|-----|-|||----|---||||||||----|||||-||||||||---|||||-- 3 [R] COG2244 Membrane protein involved in the export of O-antigen and teichoic acid -|-|--||------|--|||||--|||---||||||||-|--|||||-||||-||||||-||-|-- 3 [R] COG2252 Permeases ---|---------------|-|--------||||||||----|||||-||||||||---------- 3 [R] COG2333 Predicted hydrolase (metallo-beta-lactamase superfamily) ---------------------|--------||||||||----|||||-|--|---|---||||--- 3 [K] COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain -----------|-||---||-------|||||||-|||----|||||-||-|-|||--||||||-- 3 [E] COG2755 Lysophospholipase L1 and related esterases --|-||--|----||---||||----|||--|||||-|||--|||||-|||--|||---|||||-- 3 [L] COG2801 Transposase and inactivated derivatives --------------------|---------|-||||||----------||--|--|---------- 3 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain --------------------|---------||||||||----|||||-||--|--|---|||||-- 3 [KT] COG3279 Response regulator of the LytR/AlgR family -----------------------------------|-|----|||||-|------------||--- 3 [S] COG3394 Uncharacterized protein conserved in bacteria ------||----------------------||---|||-------|-------------------- 3 [S] COG3595 Uncharacterized conserved protein --------------------|---------|---||||-----------|-|-------||-|--- 3 [S] COG3708 Uncharacterized protein conserved in bacteria ------------------------------|-||||-|----|||-|------------------- 3 [G] COG3775 Phosphotransferase system, galactitol-specific IIC component ------------------------------||||||||---------------------------- 3 [L] COG3935 Putative primosome component and related proteins -------------------------------|--||------------------------------ 3 [R] COG4814 Uncharacterized protein with an alpha/beta hydrolase fold -------------------------------||-|||----------------------------- 3 [G] COG4975 Putative glucose uptake permease ||||||--|||||-|-|-||||||--|||||---||||----|||||-||-|||||||||||||-- 2 [H] COG0001 Glutamate-1-semialdehyde aminotransferase |||||||||||||||||||||||||||||||||||||||||||||||-|||||||||||||||||| 2 [E] COG0006 Xaa-Pro aminopeptidase ---|||----||||||--||-|||---||--|||||||-|||-------|-----|---||||||| 2 [C] COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit ||||||-|||---|||--||-|----|||--|-||||-----|||||-||-||------|--|--- 2 [P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters --|----------||-|||||-----|||||||||||||||||||||||||||||||||||||||| 2 [C] COG0055 F0F1-type ATP synthase, beta subunit --|----------||-|||||-----|||||||||||||||||||||||||||||||||||||||| 2 [C] COG0056 F0F1-type ATP synthase, alpha subunit |||||||||||||||||||||---|||||||||||||||-|||||||||||||||||||||||||| 2 [G] COG0061 Predicted sugar kinase ||||--||||--||----||-------||--|---|-|----||||--|-|---------|||--- 2 [E] COG0076 Glutamate decarboxylase and related PLP-dependent proteins |||||||||||||||-||||||----||||||--||||----||||||||||||||--||||||-- 2 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase |||||||||||||||-||||-|----||||||--||||----|||||-|||||--|||||||||-- 2 [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases ||||||-||||||||-||||||----||||||||||||----||||||||||||||||||||||-- 2 [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-- 2 [G] COG0149 Triosephosphate isomerase ||||----|||||||-||||||||||||||||||||||||||---|---|---||||||||||||| 2 [J] COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases --||||--|----||||||||||||||||||||||||||||||||||||||||||||||||||||| 2 [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit --||||--|----||||||||||||||||||||||||||||||||||||||||||||||||||||| 2 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit -------------||-|||||||||-||||||||||||||||||||||||||||||||||||||-- 2 [H] COG0196 FAD synthase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 2 [J] COG0199 Ribosomal protein S14 -------------||-|||||||||||||||||||||||||||||||-|||||||||||||||||| 2 [S] COG0217 Uncharacterized conserved protein --|----------||-|||||-----|||||||||||||||||||||||||||||||||||||||| 2 [C] COG0224 F0F1-type ATP synthase, gamma subunit ||||-||||||-|||-||-||------||||-||-|||-||-|||||-|||||--|||--|||||| 2 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases --|----------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 2 [IQ] COG0236 Acyl carrier protein -|||--||-|---||-||||-|----|||-|--|||||----|||||-||||||||||||||||-- 2 [D] COG0239 Integral membrane protein possibly involved in chromosome condensation |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 2 [L] COG0258 5'-3' exonuclease (including N-terminal domain of PolI) --|----------|||-|--||||--||||||||||||||||||||||||||||||---|||||-| 2 [H] COG0262 Dihydrofolate reductase |-||------||-||-||||||||||||||||||||||----|||||||||||||||||||||||| 2 [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain -------------||-|||||||||||||||||||||||||||||||||||||||||||-|||||| 2 [J] COG0267 Ribosomal protein L33 --||-------------||-||--|||||-||||||||||||||||||||||||||-||||||||| 2 [C] COG0280 Phosphotransacetylase --|--------------|||||--|||||-||||||||||||||||||||||-||-|||-|||-|| 2 [C] COG0282 Acetate kinase ||||||||||||-|---|-|-|||--|||||---||||----||||||||||-||||||||-|--- 2 [P] COG0306 Phosphate/sulphate permeases ----------------||||||---||||||||||||||-|||||||-||||||||||||||||-| 2 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases |-||------------|||||||||||||||||||||||||||||||-|||||||||||||||||| 2 [L] COG0322 Nuclease subunit of the excinuclease complex ||||--||||---|||---|||||||||-|||||||||||--||||||||||-||||||------- 2 [S] COG0327 Uncharacterized conserved protein -------------||-||||||||||----|||||||||||||||||||||||||||||||||||| 2 [J] COG0333 Ribosomal protein L32 |-|-||----|||||-||||-|--|-||||||||||||----|||||-||||||||||||||||-- 2 [E] COG0345 Pyrroline-5-carboxylate reductase |||||||||||||||-||-|||--|-||||||||||||----|||||-||||||||||||||||-- 2 [H] COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase --|----------||-|||||-----|||||||||||||||||||||||||||||||||||||||| 2 [C] COG0355 F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) |-||||--|-|||||||-||-|-----||--|--||||----|||||-||-||--||-||||||-- 2 [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases |-|||||||-|||||-||||-|--|-|||||--|||||----|||||-||--||||||||||||-- 2 [R] COG0388 Predicted amidohydrolase ||||--||||------||||------|||||---|||-|||||||-|--|--|--|---||||--- 2 [S] COG0392 Predicted integral membrane protein -------------||---||-|||-------|--||||----|||----|--|------||||-|| 2 [R] COG0400 Predicted esterase ||||||||||||||||||||||--||||||||--||||----|||||-||----------|----- 2 [L] COG0420 DNA repair exonuclease ||||||||||||||||||||||---|||||||||||||----|||||-|||||||||||||||||| 2 [M] COG0438 Glycosyltransferase |||||||||||||||-||||||--||||||||||||||||||||||||||||||||||||||||-| 2 [FE] COG0462 Phosphoribosylpyrophosphate synthetase ---|||----|||||---||-|||--||||-|||||||-|||||||||||||||||---||||||| 2 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes ||||||-||||||||-||||||----||||||||||||----||||||||||||||||||||||-- 2 [EH] COG0512 Anthranilate/para-aminobenzoate synthases component II --|---------||||--||||--|-|---||--||||----|||||-||||||||---||-||-- 2 [L] COG0514 Superfamily II DNA helicase ---|||----||-||||-||-|||--||||||||||||||||-|-|--|||||--||--|--|--- 2 [RTKL] COG0515 Serine/threonine protein kinase |||||||||||||||-||||||-|-|||||||||||||----|||||-||||||||||||||||-- 2 [F] COG0518 GMP synthase - Glutamine amidotransferase domain |||||||||||||||--|||-|----||||||||||||----|||||-|||||--|---|||||-- 2 [G] COG0524 Sugar kinases, ribokinase family |-||--|||----|--|-||-|--|||||-|||||||||---|||||-||||||||||||||||-- 2 [R] COG0546 Predicted phosphatases --------|----||-|||||||||||||||||||||||||||||||-|||||||||||||||||| 2 [J] COG0566 rRNA methylases |||||||||||||---||||||--|-|||||--|-||-----|||||-||--|||||||||||||| 2 [G] COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase |-------|--|-|||-||-||---|----||||||||-|||||||||-||||--|---|||||-- 2 [G] COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) ---|||-|--|-||||-|-|||--|-||||||||||||-||||||||-||||---|---|||||-- 2 [C] COG0584 Glycerophosphoryl diester phosphodiesterase ||||--||-|-------|||||----||||||||||||||||--------------|||||||||| 2 [R] COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily ----------|-|||-||||||---|-|||||||||||----|||||-|||||--||||||||||| 2 [R] COG0612 Predicted Zn-dependent peptidases |||||||||||||||-||-----|--||||-|-|||||----||||||||||||||--||--||-- 2 [E] COG0620 Methionine synthase II (cobalamin-independent) --||||||--|||||--|--||----||||||||||||----|||||-||||||||||||||||-- 2 [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases ||||||||||-||||||||||||||||||||||||||||||||||||||||||||||||||||||| 2 [C] COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 2 [U] COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase) --|----------||||-||--||--||||-|---|||----|||-|-||-|---|||-||-|--- 2 [P] COG0659 Sulfate permease and related transporters (MFS superfamily) ---|||----|||||-||||||---|||||-|--||||----|||||-||--|--||--||-||-- 2 [C] COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) ||||--||-|-|-||||-||||--|-||||||||||||----|||||-|||||--|||-||||||| 2 [I] COG0671 Membrane-associated phospholipid phosphatase -------------|||----||||-|||||-||||||||||||||||||||||||||||||----- 2 [L] COG0692 Uracil DNA glycosylase -||||||||||||||-|-||||--||-||-|--|||||-||||||||-||-||--|--||||||-- 2 [R] COG0693 Putative intracellular protease/amidase ---|---------||-|-||-|----|----|--||||----|||||-|||-|--|---|||||-- 2 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epimerases -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 2 [U] COG0706 Preprotein translocase subunit YidC |||-----||---||---|||---|-----||||-||-----|||||||||||--||||------- 2 [C] COG0716 Flavodoxins |||||||||||||----|||-||||-||||||||||||----|||||-----|------|||||-- 2 [O] COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component |||||||||||||---||||||----|--|||--||||----|||||-||||||||||||||||-- 2 [R] COG0730 Predicted permeases ||||-|-||----------|-------||--|||||--|||||||-|-|||||---|||-||-|-| 2 [V] COG0732 Restriction endonuclease S subunits |--|----|----||-|||--|--|-|---|||-||||-|--|||||-|-||---|||-||-|--- 2 [F] COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases ----------------||||||--||||||||--||||----|||||||||||||||||||||||| 2 [M] COG0739 Membrane proteins related to metalloendopeptidases ----------------||||||||||||||||||||||----|||||||||||||||||||||||| 2 [OU] COG0740 Protease subunit of ATP-dependent Clp proteases -----------------|||||----||||||||||||----||||||||||||||||||||||-- 2 [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein) -------------|||||||||--||----||||||||----|||||||||||||||||||||||| 2 [O] COG0760 Parvulin-like peptidyl-prolyl isomerase ----------------||||||||||||||||||||||----|||||||||||||||||||||||| 2 [M] COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase |-||--|||----|||-|||-|--||-||-|----|||----|||||-|||||--|||||||||-- 2 [T] COG0784 FOG: CheY-like receiver |-|---|-|----|---|||------|||-|----||--------------|--|----|------ 2 [P] COG0798 Arsenite efflux pump ACR3 and related permeases |||------|-|----|--|||--------||||||||----|||||-||||-|||||||||---- 2 [O] COG0826 Collagenase and related proteases -|-------------------------|||||||||||------------|-----||-|--|--- 2 [L] COG0827 Adenine-specific DNA methylase --||--|||--------|||-|--||----|----|||----|||||-||--|--||||||-||-- 2 [NT] COG0840 Methyl-accepting chemotaxis protein ----------------||||||--|||---|-||||||----|||||-|||||||||||||||||| 2 [M] COG0845 Membrane-fusion protein ------------------||-|----|||-|---||||----|||||||||||||||||||||||| 2 [P] COG0861 Membrane protein TerC, possibly involved in tellurium resistance -|-||||----------|-|||----------|--|-|----|||||-|-|-||-|||-|||||-- 2 [L] COG0863 DNA modification methylase ||||--||-|||-|||-|-|-|--|||||-||||||||----|||||-||-|-|||---|||||-- 2 [R] COG1011 Predicted hydrolase (HAD superfamily) ----------------||||||--||-||-||||||||----|||||-||||||||||||||||-| 2 [R] COG1040 Predicted amidophosphoribosyltransferases |||---|||||||---|-||-|----||||||-|-|||-------|--||-----|---|||||-| 2 [F] COG1051 ADP-ribose pyrophosphatase --------|---|||--|||----|||||-||-|||||----|||||--|||---|---||||--- 2 [G] COG1070 Sugar (pentulose and hexulose) kinases ---|||----||||||--||-|||---||--|||||||-|||-------|-----|---||||||| 2 [C] COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit -----------------|---|--------||||||||---------------------------- 2 [J] COG1098 Predicted RNA binding protein (contains ribosomal protein S1 domain) -----------------|--||---||||-||||||||--|||||||-||||---|---------- 2 [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) ||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||-- 2 [P] COG1117 ABC-type phosphate transport system, ATPase component --------|----------|||-----||-|||||||-----|||||--|------||-||||--- 2 [E] COG1125 ABC-type proline/glycine betaine transport systems, ATPase components ------------------||||-||-|---||||||||----|||||-||||||||||||||||-- 2 [P] COG1135 ABC-type metal ion transport system, ATPase component -||---||-|||||||-||||----|----||||||||||||------|----||----------- 2 [R] COG1161 Predicted GTPases --|-------------|||||----||||||||||||||||||||||-||||||||------|--- 2 [R] COG1162 Predicted GTPases --||-------------|--||||||-----|||||||||||------|-------||||||||-- 2 [E] COG1164 Oligoendopeptidase F --|-------------||||||||||||||||||||||----|||||-|||||||||||||||||| 2 [M] COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes -------------------|----------||--||||-||||||||--||----|---||-|--- 2 [I] COG1182 Acyl carrier protein phosphodiesterase ----------------||||||||||||||||||||||-|--|||||||||||||||||||||||| 2 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases ||-|-|||-|||----|-||-||||||||||----|||--|||||||-||--|||||||||||||| 2 [D] COG1192 ATPases involved in chromosome partitioning ||||||||--|||||||-|||-----|||-||||||||----|||||-||||||||-------|-- 2 [KL] COG1199 Rad3-related DNA helicases ------|---------|||||||||-|||||--|||||--||||||||||||||||||||||||-- 2 [I] COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase -----------------|||----------|----||-----|||||-||-----|---------- 2 [KT] COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain ||||||||||||||||-|||-|||||||||||||||||----|||-|----|---|------||-- 2 [R] COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III ---|-------|-||---||-|----||||-|--||||----|||||-|||----|---||||--- 2 [C] COG1252 NADH dehydrogenase, FAD-containing subunit --------------------|----||---||||||||-|||||||||||-|---|-------|-- 2 [G] COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific --------------------|----||---||||||||||||||||||||-|---|-------|-- 2 [G] COG1264 Phosphotransferase system IIB components --------------------|---|-|-----||||||-|--|||-|-||--------|||||--- 2 [P] COG1283 Na+/phosphate symporter -----------------|--||||------||||||||---------------------------- 2 [S] COG1302 Uncharacterized protein conserved in bacteria |-|---||||||----||||-|-----||||----|||-----------||||--|---||-||-- 2 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases --|||||||||||||-||-|-|--|||||-||||||||----|||||-||--||||--||||||-- 2 [Q] COG1335 Amidases related to nicotinamidase ----------------||------||----|----|||----|||||-||-----|||||||||-- 2 [N] COG1344 Flagellin and related hook-associated proteins -----------------|------------|||-|||-----|||-|-||||-||-|||||-|--- 2 [M] COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily |||-||||||---||-||--||-----||-||--||||----|||||-|-----------|----- 2 [ER] COG1387 Histidinol phosphatase and related hydrolases of the PHP family -------------------|||----|--||||||||||-|||||||-||||||||--||||||-- 2 [P] COG1393 Arsenate reductase and related proteins, glutaredoxin family |-|-------|-----|--|-|||--||||||---|||----|------------||||-|-|--- 2 [R] COG1408 Predicted phosphohydrolases ||||||||||------||--||--||----|||||||||-|||||-|---------|||||----- 2 [R] COG1418 Predicted HD superfamily hydrolase ----------------||||-|----|---||--||------|||||-||||||||---||||||| 2 [S] COG1434 Uncharacterized conserved protein -----------------|--||----|||-||||||||||||------------------------ 2 [R] COG1461 Predicted kinase related to dihydroxyacetone kinase --------------------||-||-|---||||||||----|||||-||||||||||||||||-- 2 [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen -|||--|----------|-||-----|---|----|--||---|||--|--|--|-|||------- 2 [S] COG1479 Uncharacterized conserved protein ----||--|-|--|||-||||-||--|---||||||||||--||||||||||||||||-||||||| 2 [I] COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes ------|------|-----|-------|||||---||--|--|||--------||----------- 2 [G] COG1554 Trehalose and maltose hydrolases (possible phosphorylases) --|--------------|||||----|||-||||||||----|||||-||||||||--|------- 2 [L] COG1555 DNA uptake protein and related DNA-binding proteins ---|-------------||||-----||||-|--|||-----|||||-|-||-------------- 2 [H] COG1575 1,4-dihydroxy-2-naphthoate octaprenyltransferase ||||--||||||||||---------|-----|||||------------------------------ 2 [I] COG1577 Mevalonate kinase ||||||--||||-||-|-||||||--|||||---||||----|||||-||-||||||||||||--- 2 [H] COG1587 Uroporphyrinogen-III synthase ----||------------||||--|-----||-|-|||-|--|||-|-||---|||--------|| 2 [V] COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF --------------------|-||||||||||||||||----|||||-||||||||---||||||| 2 [M] COG1686 D-alanyl-D-alanine carboxypeptidase ---|----|----------|||-----||-|||||||-----|||-|--|-----|||-||||--- 2 [M] COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) --------------------||----||||||||||||----|||||-||||-|||||||||||-- 2 [E] COG1760 L-serine deaminase -||-||||-|-||---||---|----|||-|----|-|--|||||||-||---|||---||-||-- 2 [O] COG1765 Predicted redox protein, regulator of disulfide bond formation -------------------------|------|--||-------------|--------------- 2 [R] COG1783 Phage terminase large subunit ---------------------|------------||||----|||||-||--||||---||||||| 2 [S] COG1806 Uncharacterized protein conserved in bacteria -----------|-----|-|||---||||-||||||||-|--|||||-|||||------|||||-- 2 [G] COG1820 N-acetylglucosamine-6-phosphate deacetylase |-|-|-|||-|||-|-||||||----||||||-|||||----|||||--|-|-|||---||||||| 2 [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family |-------|-----------|---------||||||------|||||-|-||---|---------- 2 [C] COG1882 Pyruvate-formate lyase ------------------||-|----||||||--||||----|||-|--|-----|--|||----- 2 [S] COG1937 Uncharacterized protein conserved in bacteria --|---||---------|--------|---||||-|||----|||||-|----------------- 2 [KT] COG1983 Putative stress-responsive transcriptional regulator --------------------||-||-|---||||||||----|||||-||||||||||||||||-- 2 [P] COG2011 ABC-type metal ion transport system, permease component ----||-----|-||--|||||--------||-|||||----|||-|-|-||-|||---|||||-- 2 [G] COG2017 Galactose mutarotase and related enzymes --|||||||-||--|-|----|----|||--|||||||----|||||-||||---|||||||||-- 2 [Q] COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism ---|||------------||-|-----||-|---||------|||||--|-----|---||-||-- 2 [P] COG2060 K+-transporting ATPase, A chain --------|----|--||-|||----|||-||||||||-----------|--||||||||||-|-- 2 [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase --||---------------|-|-----|||||---|||----|||||-||---||---||||||-- 2 [P] COG2076 Membrane transporters of cations and cationic drugs --------|-----------|----|----|---||||---------------------------- 2 [M] COG2088 Uncharacterized protein, involved in the regulation of septum location ---||||||-|||-------||----||||-----|||--------|--|-----|---|||||-- 2 [S] COG2096 Uncharacterized conserved protein ||||--||---------|||-|----|-------||||----------||---------|||--|| 2 [P] COG2111 Multisubunit Na+/H+ antiporter, MnhB subunit --|----------------------|-----||--||-----|||||--|-----|---||||--- 2 [E] COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components ---------|---|------|---------|||||||-----|||||-||||-------------- 2 [P] COG2116 Formate/nitrite family of transporters ||||----||-|-------|-|----||||--||||||-|--|||||--|--|--|---|||||-- 2 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases ---|||------------||-|-----||-|---||------|||||--|-----|---||-||-- 2 [P] COG2156 K+-transporting ATPase, c chain ----------------||||||||------||||||||----|||||-|||||--|--|---||-- 2 [NU] COG2165 Type II secretory pathway, pseudopilin PulG ---------------------------||--|---|||----|||||-||-----|---|||||-| 2 [F] COG2169 Adenosine deaminase -----------------|||-|||---||-|---||||---------------------------- 2 [T] COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase) --------------------|----||---||||||||-|||||||||||||---|-------|-- 2 [G] COG2190 Phosphotransferase system IIA components --|-----------------||---|----||||||||----|||||-|-||------|-|--|-- 2 [E] COG2195 Di- and tripeptidases ------------------||-|----|||-||||||||----|||||-||||||||---|||||-- 2 [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain |-||----|-----|-||||-|||-||||||----|||----|||||-||--|--|--||||||-- 2 [T] COG2202 FOG: PAS/PAC domain ------------------||-|-----||-|---||------|||||-||-----|--|||-||-- 2 [T] COG2205 Osmosensitive K+ channel histidine kinase ---|||------------||-|-----||-|---||------|||||--|-----|--|||-||-- 2 [P] COG2216 High-affinity K+ transport system, ATPase chain B -------|------|--|--||----|---||||||||----|||||-||||-|||---|||---- 2 [F] COG2233 Xanthine/uracil permeases --|-----------|-----|---------|----||||---|||||-||||-||||||-|-||-- 2 [R] COG2249 Putative NADPH-quinone reductase (modulator of drug activity B) -|||--||-||||---||||||||--||||||||||||----|||||-||-|||||---|||||-- 2 [R] COG2262 GTPases ------||-----||-||||||||--|||-||||||||----|||||-||||||||--||||||-- 2 [J] COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase ---|--|--|--|---|----|---|-------|||||---------------------||||--- 2 [E] COG2309 Leucyl aminopeptidase (aminopeptidase T) --------------------||----|----|||-||-----|||||--|-----|---|--||-- 2 [S] COG2315 Uncharacterized protein conserved in bacteria ---|||-----||--------|----||||----||||-----------|-----|---||||--- 2 [R] COG2329 Conserved protein involved in polyketide biosynthesis related to monooxygenase --------------------||----|||-||||||||---------------------------- 2 [S] COG2357 Uncharacterized protein conserved in bacteria -------------||------|-----||--|---|---------|---|-----|---|---|-- 2 [T] COG2365 Protein tyrosine/serine phosphatase ----||----|||--------|----|||||---|||----------------------------- 2 [R] COG2409 Predicted drug exporters of the RND superfamily ---------------------|----||||||||-|||-----------|---------|------ 2 [TQ] COG2508 Regulator of polyketide synthase expression -------------------|||---|-||-|--|||||--------------||-|-----|---- 2 [E] COG2856 Predicted Zn peptidase --------------------|----------|||-|------|||||-|--||------||-||-- 2 [P] COG3142 Uncharacterized protein involved in copper resistance -------------------------------|--||------|||||-||----------|-||-- 2 [S] COG3152 Predicted membrane protein -------------------|-|----|---||--||------|||-|--|-|-------|--|--- 2 [S] COG3238 Uncharacterized protein conserved in bacteria --|----------------|-------||--|--||------||||---|-----|----|||--- 2 [S] COG3247 Uncharacterized conserved protein -----------------------------------||-----|-||----|-|-|----------- 2 [S] COG3299 Uncharacterized homolog of phage Mu protein gp47 --------------------||---------|-|||-|----|||-----------------|--- 2 [S] COG3412 Uncharacterized protein conserved in bacteria --------------|----------------|||-|-|--------------|------------- 2 [S] COG3538 Uncharacterized conserved protein -----------------|---|--------||---|||---------------------------- 2 [S] COG3584 Uncharacterized protein conserved in bacteria ------------------||-|----||||||||||||-|-------------------------- 2 [D] COG3599 Cell division initiation protein -------------------------------||--|-------|||---||-|--------|---- 2 [K] COG3617 Prophage antirepressor -------------------------------|-|-||------||-----||-------------- 2 [S] COG3646 Uncharacterized phage-encoded protein ---|----|----------------------|||||||---------------------------- 2 [S] COG3679 Uncharacterized conserved protein -------------------------------||-||||----|||--------------------- 2 [L] COG3723 Recombinational DNA repair protein (RecE pathway) --||----|-|-|----|||||--|||---||||||-||||||||||-||||-|||--||||||-- 2 [E] COG3842 ABC-type spermidine/putrescine transport systems, ATPase components --------------------||--------|---|||----------------------------- 2 [S] COG3878 Uncharacterized protein conserved in bacteria ------------------------------||||-|||---------------------------- 2 [S] COG3883 Uncharacterized protein conserved in bacteria ------------------------------|----||---------|------------------- 2 [K] COG3933 Transcriptional antiterminator ---|---------------------------|---|-|-------||-||---------------- 2 [R] COG3979 Uncharacterized protein contain chitin-binding domain type 3 --------------------------|||-|-||||||---------------------|-|---- 2 [S] COG4129 Predicted membrane protein --------------------|---------||||||||---------------------------- 2 [S] COG4224 Uncharacterized protein conserved in bacteria ----------------|--------------||-|||-----|||--------------------- 2 [L] COG4570 Holliday junction resolvase ------------------|||--------------|------|||-|------------------- 2 [QC] COG4576 Carbon dioxide concentrating mechanism/carboxysome shell protein --------------------|--------------|------|||-|------------------- 2 [E] COG4816 Ethanolamine utilization protein -----------------------------------|-|-----------------------|---- 2 [R] COG4821 Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain --------------------|--------------|---------------|-------------- 2 [V] COG4823 Abortive infection bacteriophage resistance protein -----------------|-----------------|----------|------------------- 2 [Q] COG4869 Propanediol utilization protein ---|||--||-||----|||||----||||||--||||----|||||--|-----|---|||||-- 2 [MR] COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily --------------------|---|-|||||---||||----|||||-||||||||---||||||| 2 [L] COG4974 Site-specific recombinase XerD ------------------||----------|---||||---------------------------- 2 [R] COG4980 Gas vesicle protein --------------------|-----|||--||-||||----|||||-|-||-------|-|-|-- 2 [CO] COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components -------------------------------|--|||----------------------------- 2 [S] COG4990 Uncharacterized protein conserved in bacteria -----------------|--|----------|---|------------------------------ 2 [S] COG5341 Uncharacterized protein conserved in bacteria --|--------------------------------|-------------------|----|-||-- 2 [S] COG5361 Uncharacterized conserved protein -----------------------------------|||--------------|------------- 2 [L] COG5377 Phage-related protein, predicted endonuclease ----------------------------------||-|---------------------------- 2 [M] COG5386 Cell surface protein -------------------|---------------|------|||-|-----|--|---------- 2 [R] COG5525 Bacteriophage tail assembly protein --------------------------------|-||------------------------------ 2 [S] COG5546 Small integral membrane protein --------------------------|----|---|||-------------------------|-- 2 [S] COG5646 Uncharacterized conserved protein --|-----|-----------------|--------||--------------------------|-- 2 [S] COG5658 Predicted integral membrane protein |||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||-- 1 [E] COG0002 Acetylglutamate semialdehyde dehydrogenase ||-|||-|-||-|||-|-|||------|||-----|-|---------------------------- 1 [P] COG0003 Oxyanion-translocating ATPase |||-||--||-|-||-||||-|----|||-||--|||||---|||||--|--||||---|||||-- 1 [P] COG0004 Ammonia permease |||||||||||||||-||||-------||||-||-|||----|--||--|--|------||-|--- 1 [F] COG0005 Purine nucleoside phosphorylase ||||||--|||||||-|-||||----|||||---||||----||||||||--||||---|||||-- 1 [H] COG0007 Uroporphyrinogen-III methylase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0008 Glutamyl- and glutaminyl-tRNA synthetases ||||||||||||||||||||||||||||||||||||||||||||||||||||||||---||||||| 1 [J] COG0009 Putative translation factor (SUA5) |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0012 Predicted GTPase, probable translation factor |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0013 Alanyl-tRNA synthetase --|----------||-||||-|--|-||||||||-|||----|||||-||||||||--||||||-- 1 [E] COG0014 Gamma-glutamyl phosphate reductase ||||||||||||-||-||||||----||||||||||||----||||||||||||||||||||||-- 1 [F] COG0015 Adenylosuccinate lyase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0016 Phenylalanyl-tRNA synthetase alpha subunit ||||||||||||||||--||||--||----|||||||||||||||||||-|||------------- 1 [J] COG0017 Aspartyl/asparaginyl-tRNA synthetases |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0018 Arginyl-tRNA synthetase |||-||--||---||-||||-|----||||||-|||||----||||||||||||||||||||||-- 1 [E] COG0019 Diaminopimelate decarboxylase ||||||||||||||||||||||||||||||||||||||----|||||||||||||||||||||||| 1 [I] COG0020 Undecaprenyl pyrophosphate synthase ||||||||||||||||||||||||||||||-||||||||||||||||||||||||||||||||||| 1 [J] COG0024 Methionine aminopeptidase ---|||----||-||-||||-|----||||-|||||||----|||||-||||||||---|||||-- 1 [F] COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) ---|--||---|----|-|||------||||----|||----|||||-||--||||---||-||-- 1 [H] COG0029 Aspartate oxidase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0030 Dimethyladenosine transferase (rRNA methylation) --||||-|--|||||-||||||----||||||||||||----||||||||||||||||||||||-- 1 [E] COG0031 Cysteine synthase ||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||-- 1 [F] COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase |--|---|--|||||-||||||--|-|||-|||||||||||||||||-||||-|||--||||||-- 1 [F] COG0035 Uracil phosphoribosyltransferase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [D] COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control ||||----||||-||-||||-|----||||||--||||----|||||||||||||---||||||-- 1 [E] COG0040 ATP phosphoribosyltransferase ||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||-- 1 [F] COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase ||||----||---|||||||||||||||||||||||||----|||||-|||||||||||||||||| 1 [J] COG0042 tRNA-dihydrouridine synthase |||||||||||||||-||||||----||||||||||||----|||-|--|--|--|||||||||-- 1 [F] COG0044 Dihydroorotase and related cyclic amidohydrolases ||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||-- 1 [F] COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain ||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||-- 1 [F] COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0048 Ribosomal protein S12 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0049 Ribosomal protein S7 ---------|---||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0050 GTPases - translation elongation factors |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-|||||| 1 [J] COG0051 Ribosomal protein S10 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0052 Ribosomal protein S2 ||||||||||||||||||||||||||||||||||||||-|||||||||||||||||||||||||-- 1 [G] COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase |||----|||||-|--||||-|----||||||-|||||----||||||||||||||||||||||-- 1 [EH] COG0059 Ketol-acid reductoisomerase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0060 Isoleucyl-tRNA synthetase ||||||||||||||||||||-|----||||||--|||-----|||||-||--||||||||||||-- 1 [G] COG0063 Predicted sugar kinase ||||----||-||||-||||||||||||||||||||||||||-------|---||||||||||||| 1 [J] COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) ||||--||||||-||-||||-|----||||||--||||----||||||||||||||--||||||-- 1 [E] COG0065 3-isopropylmalate dehydratase large subunit |||---||||||-||-||||-|----||||||-|||||----||||||||||||||--||||||-- 1 [E] COG0066 3-isopropylmalate dehydratase small subunit |||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||-- 1 [E] COG0067 Glutamate synthase domain 1 |||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||-- 1 [E] COG0069 Glutamate synthase domain 2 |||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||-- 1 [E] COG0070 Glutamate synthase domain 3 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0072 Phenylalanyl-tRNA synthetase beta subunit ||||||--||||-||-||||-|----||||||-|||||----|||-||||||||||--||||||-- 1 [E] COG0077 Prephenate dehydratase |||||||||||||||-||||-|---|||||||||||||--|-||||||||||||||--||||||-- 1 [E] COG0078 Ornithine carbamoyltransferase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0080 Ribosomal protein L11 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0081 Ribosomal protein L1 ||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||-- 1 [E] COG0082 Chorismate synthase -|-|||||-||||||-||||-|----||||||-|||||----|||||||-|||---|||------- 1 [E] COG0083 Homoserine kinase |||---||-||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [L] COG0084 Mg-dependent DNase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [K] COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [K] COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0087 Ribosomal protein L3 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0088 Ribosomal protein L4 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0089 Ribosomal protein L23 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0090 Ribosomal protein L2 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0091 Ribosomal protein L22 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0092 Ribosomal protein S3 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0093 Ribosomal protein L14 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0094 Ribosomal protein L5 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0096 Ribosomal protein S8 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0097 Ribosomal protein L6P/L9E |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0098 Ribosomal protein S5 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0099 Ribosomal protein S13 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0100 Ribosomal protein S11 |||||||||||--||||||||||||||||||||||||||-|||||||||||||||||||||||||| 1 [J] COG0101 Pseudouridylate synthase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0102 Ribosomal protein L13 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0103 Ribosomal protein S9 ||||||||||||-||-||||||----||||||||||||----||||||||||||||||||||||-- 1 [F] COG0104 Adenylosuccinate synthase |||||||||||||||||-||-||||||||||--|||||----|||||-|||||||||||||||||| 1 [F] COG0105 Nucleoside diphosphate kinase ||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||-- 1 [E] COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase ||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||-- 1 [E] COG0107 Imidazoleglycerol-phosphate synthase ---|||--|-|||||-|-||-|----||||----||||----||||||-|--|--|---||||||| 1 [O] COG0109 Polyprenyltransferase (cytochrome oxidase assembly factor) ||||||||||||||||||||-|||||||||||||||||-||||||||||||||||||||||||||| 1 [E] COG0112 Glycine/serine hydroxymethyltransferase ||||||--|||||||-|-||||||--|||||---||||----|||||-||-||||||||||||||| 1 [H] COG0113 Delta-aminolevulinic acid dehydratase --||------|||||---|--|||--||||----||||----|||||-|||||||||||||||||| 1 [C] COG0114 Fumarase -|----|||||-|-----|-||--------||||||||----||||||||||||||---------- 1 [L] COG0116 Predicted N6-adenine-specific DNA methylase ||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||-- 1 [E] COG0118 Glutamine amidotransferase |||--|||||||-||-||||-|----|||||--|||||----||||||||||||||--||||||-- 1 [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases ||||||||||||||||--||-|||||----||||||------||||||||||||||---|||||-- 1 [G] COG0120 Ribose 5-phosphate isomerase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0124 Histidyl-tRNA synthetase ||||||||||||||||||||||||||||||-||||||||||||||||||||||||||||||||||| 1 [F] COG0125 Thymidylate kinase ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-- 1 [G] COG0126 3-phosphoglycerate kinase ||||||||||||||||||||||||||||||||||||||----|||||-||||||||--||||||-- 1 [F] COG0127 Xanthosine triphosphate pyrophosphatase ||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||-- 1 [E] COG0128 5-enolpyruvylshikimate-3-phosphate synthase |||----||||||||-||||-|----||||||-|||||----||||||||||||||||||||||-- 1 [EG] COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase ||||||||||||||||||||||||||||||||||||||||--||||||||||||||--|||||||| 1 [J] COG0130 Pseudouridine synthase ||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||-- 1 [E] COG0131 Imidazoleglycerol-phosphate dehydratase ||||---|||---||-|||||||---||||||-|||||----||||||||||||||||||||||-- 1 [E] COG0133 Tryptophan synthase beta chain ||||||-||||||||-||||-|----||||||-|||||----||||||||||||||||||||||-- 1 [E] COG0134 Indole-3-glycerol phosphate synthase ||||||-||||||||-||||-||---|---||-|||||----||||||||||||||||||||||-- 1 [E] COG0135 Phosphoribosylanthranilate isomerase |||||-|||||||||-||||-|||--||||||-|||||----|||||||||||||||||||||||| 1 [E] COG0136 Aspartate-semialdehyde dehydrogenase ||||||--||||-||-||||-|----||||||--||||----||||||||||||||--||||||-- 1 [E] COG0137 Argininosuccinate synthase --||||--|----||-||||||----||||||-|||||----||||||||||||||--||||||-- 1 [F] COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) ||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||-- 1 [E] COG0139 Phosphoribosyl-AMP cyclohydrolase ||||-----|||-||-||||-|----||||||--||||----||||||||||||||--||||||-- 1 [E] COG0140 Phosphoribosyl-ATP pyrophosphohydrolase ||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||-- 1 [E] COG0141 Histidinol dehydrogenase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0143 Methionyl-tRNA synthetase -|-|--||||||||||-|||||||--|||-||||||||----|||||-||||||||--||||||-- 1 [J] COG0144 tRNA and rRNA cytosine-C5-methylases -||--|--|||||||-|-||-------|-------|-|------------------||-|||||-- 1 [EQ] COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-- 1 [G] COG0148 Enolase ||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||-- 1 [F] COG0150 Phosphoribosylaminoimidazole (AIR) synthetase ||||||||||||-||-||||||----||||||||||||----|||||-||||||||||||||||-- 1 [F] COG0151 Phosphoribosylamine-glycine ligase ||||||||||||-||-||||||----||||||||||||----|||||-||||||||--|||||||| 1 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase ||||--||||||-|--|||||-----|||||-||-|||----|||||-||||||||||-||-||-- 1 [H] COG0157 Nicotinate-nucleotide pyrophosphorylase ||||||-||||||||-||||-||---||||||-|||||----||||||||||||||||||||||-- 1 [E] COG0159 Tryptophan synthase alpha chain |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0162 Tyrosyl-tRNA synthetase ||||||||||||||||||||||||-|||||||||||||----|||||-|||||||||||||||||| 1 [L] COG0164 Ribonuclease HII ||||||--||||-||-||||-|----||||||--||||----||||||||||||||--||||||-- 1 [E] COG0165 Argininosuccinate lyase -|-|||----||||||||||||||||||||||||||||-|||||||||||||||||||||||||-- 1 [G] COG0166 Glucose-6-phosphate isomerase |||||||||||||||-||||||----||||||||||||----||||||||||||||||||||||-- 1 [F] COG0167 Dihydroorotate dehydrogenase ||||--||||--|||-||||||--||------||||||-||||||||-||||-||---||||---- 1 [P] COG0168 Trk-type K+ transport systems, membrane components |||||||||||||||-||||||--||||||||||||||||||||||||||--||||||||||||-- 1 [H] COG0171 NAD synthase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0172 Seryl-tRNA synthetase -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0173 Aspartyl-tRNA synthetase |||||||||||||||-||||-|----||||-|||||||----|||||-|||||||||||||||||| 1 [E] COG0174 Glutamine synthetase ||||||||||||||||||||||||||||||||||||||----|||||||||||||||||||||||| 1 [L] COG0177 Predicted EndoIII-related endonuclease |||||||||||||||---||-|----||||----||||----|||||-||-|-|||--||||||-- 1 [Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0180 Tryptophanyl-tRNA synthetase ||||||--|||||||-|-||||||--|||||---||||----||||||||-||||||||||||||| 1 [H] COG0181 Porphobilinogen deaminase ||||||||||||||||--|-||---||||||||-||||----|||||-|||----|||-||||||| 1 [I] COG0183 Acetyl-CoA acetyltransferase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0184 Ribosomal protein S15P/S13E |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0185 Ribosomal protein S19 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-|||||| 1 [J] COG0186 Ribosomal protein S17 --||||----||-||-|||||||||||||||||||||||||||||||||||||-|||||||||||| 1 [H] COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase -------------||-||||||--||||||||||||||||||||||||||||||||||||||||-- 1 [H] COG0192 S-adenosylmethionine synthetase -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0193 Peptidyl-tRNA hydrolase -------------|||||||||||--|||||||||||||||||||||||||||||||||||||||| 1 [F] COG0194 Guanylate kinase |||||||||||||---|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [K] COG0195 Transcription elongation factor |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0197 Ribosomal protein L16/L10E |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0198 Ribosomal protein L24 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0200 Ribosomal protein L15 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [U] COG0201 Preprotein translocase subunit SecY ||-||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [K] COG0202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0203 Ribosomal protein L17 -------------||||||||||||||||||||||||||||||||||-|||||||||||||||||| 1 [I] COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase -------------||||||||||||||||||||||||||||||||||||-|||------||-|--- 1 [G] COG0205 6-phosphofructokinase ||||||||||------||||||--||||||||||||||-||||||||||||||||||||||||||| 1 [D] COG0206 Cell division GTPase |||-----||---|||----||----||||||||||||-|||||||||||||||||---|||||-- 1 [F] COG0207 Thymidylate synthase ---|-------|-||||-|-|||||-||||||||||||-|||||||||||||||||||||-|-||| 1 [F] COG0208 Ribonucleotide reductase, beta subunit |-|||||||-|||||||||-|||||-||||||||||||-||||||||||||||||||||||||||| 1 [F] COG0209 Ribonucleotide reductase, alpha subunit |-||||-------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [L] COG0210 Superfamily I DNA and RNA helicases -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0211 Ribosomal protein L27 |--|-----||||||-|-|||||||-||||||-|||||--|||||||-|||||||||||||||||| 1 [H] COG0212 5-formyltetrahydrofolate cyclo-ligase -||---|||--------|---|-----||-||-||||||||||||-|-|------|---||-|--- 1 [F] COG0213 Thymidine phosphorylase |||||||||||||||--|--||----|||||--|||||------------||-------------- 1 [H] COG0214 Pyridoxine biosynthesis enzyme --|||||||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0215 Cysteinyl-tRNA synthetase -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0216 Protein chain release factor A -|||--||||---|--||--|---------|||||||||||||||||||||||||||||||||||| 1 [R] COG0218 Predicted GTPase -------------||||||||||||-|||||||||||||||||||||||||||||||||||||||| 1 [R] COG0220 Predicted S-adenosylmethionine-dependent methyltransferase |-||||||-|-||||||-||||||--|||||----|-||||||||||||||||||||||||||||| 1 [C] COG0221 Inorganic pyrophosphatase -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0222 Ribosomal protein L7/L12 -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0223 Methionyl-tRNA formyltransferase |-||-------|-||---||||--|-|||||||||||||||||||||-||||||||||||||||-- 1 [O] COG0225 Peptide methionine sulfoxide reductase ||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||-- 1 [P] COG0226 ABC-type phosphate transport system, periplasmic component -------------||-|||||||||||||-|||||||||||||||||||||||||||||-|||||| 1 [J] COG0227 Ribosomal protein L28 -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0228 Ribosomal protein S16 |-||---------||---||||--|-|||-||||||||-||||||||-||||||||||||||||-- 1 [O] COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase -------------||-||||-||||||||||||||||||||||||||||||||||||||-|||||| 1 [J] COG0230 Ribosomal protein L34 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) ------------------|--|----||||-----|------|||||-||||---|---||||||| 1 [F] COG0232 dGTP triphosphohydrolase -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0233 Ribosome recycling factor --|----------||-||||||||||||||||||||||--|||||||||||||||||||||||||| 1 [O] COG0234 Co-chaperonin GroES (HSP10) ||||||||||||||||||||||||||||||||||||||-||||||||||||||||||||||||||| 1 [H] COG0237 Dephospho-CoA kinase -------------||-|||||||||||||||||||||||||||||||||||||||||||-|||||| 1 [J] COG0238 Ribosomal protein S18 |-------|----|||||||||||||||||||||||||||--|||||-|||||||||||||||||| 1 [C] COG0240 Glycerol-3-phosphate dehydrogenase ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0242 N-formylmethionyl-tRNA deformylase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0244 Ribosomal protein L10 ----------------|||||||||-|||||----|||--||||||||||||||||||||||||-- 1 [I] COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase --||-|-------|||||||||||||----|||-||||----||||||||||||||---||||||| 1 [L] COG0249 Mismatch repair ATPase (MutS family) |||||||||||||-|-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [K] COG0250 Transcription antiterminator ---|--||--|||||-||||||----||||||||||||----||||||||||||||||||||||-- 1 [J] COG0251 Putative translation initiation inhibitor, yjgF family |||||||||||||||-----||----||||||||||||----|||||-|||-||||||||-|---- 1 [EJ] COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D ||------||------|||||-||--|||||---||||----|||||||||||||||||||||||| 1 [E] COG0253 Diaminopimelate epimerase ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0254 Ribosomal protein L31 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0255 Ribosomal protein L29 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0256 Ribosomal protein L18 -------------||-||||-||||||||||||||||||||||||||||||||||||||-|||||| 1 [J] COG0257 Ribosomal protein L36 ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0261 Ribosomal protein L21 --|----------||-||||-|--|-||||||||-|||----|||||-||||||||--||||||-- 1 [E] COG0263 Glutamate 5-kinase --------------|-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0264 Translation elongation factor Ts ------------------||-|----||||-||||||||||||||||-||||||||---|||||-| 1 [L] COG0266 Formamidopyrimidine-DNA glycosylase ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0268 Ribosomal protein S20 ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [L] COG0272 NAD-dependent DNA ligase (contains BRCT domain type II) |--|||----|-|---||||-|--|-|||||||||||||||||||||-|-||-------||-|--- 1 [F] COG0274 Deoxyribose-phosphate aldolase ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [M] COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis ----||-------||-|-||-|||--||||-|-|||||----|||||-|||||||||||||||||| 1 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) --|||||||-|||||--|||-|----|||-|||-||||----|||||-||||||||--|||||||| 1 [C] COG0281 Malic enzyme ---------------||||||||||||||||||||||||||||||||-||||||||---||||||| 1 [F] COG0283 Cytidylate kinase |||||||||||||||-||||||----||||||||||||----||||||||||||||||||||||-- 1 [F] COG0284 Orotidine-5'-phosphate decarboxylase ---|||-------||-||||||--|-||||||||||||----|||||||||||||||||||||||| 1 [H] COG0285 Folylpolyglutamate synthase ||||||--|||||||-||||-|----||||||-|||||----|||||-||||||||||||||||-- 1 [E] COG0287 Prephenate dehydrogenase |||-----||------||||--||--|||-||-|||||----|||||||||||||||||||||||| 1 [E] COG0289 Dihydrodipicolinate reductase ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0290 Translation initiation factor 3 (IF-3) -------------|--|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0291 Ribosomal protein L35 ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0292 Ribosomal protein L20 |||||||||||||||-||||||||--||||||||||||----|||||-||||||||||||||||-| 1 [H] COG0294 Dihydropteroate synthase and related enzymes ---|------|-|||--|---|---|-||||||||||||||||||||-|-||-------||-||-- 1 [F] COG0295 Cytidine deaminase --||||----|--||-||||||----||||||||||||----|||||-||||||||--||||||-- 1 [F] COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN |||||||||||||----|------|-----|||||||||||||||||-||||-------------- 1 [H] COG0301 Thiamine biosynthesis ATP pyrophosphatase ----------||-||-|-||||----||||||||-|||----|||||-|||||--||||||||||| 1 [H] COG0302 GTP cyclohydrolase I |||||||||||||---|-||-|----|||||---||||----|||||-||||---|||||||||-- 1 [H] COG0303 Molybdopterin biosynthesis enzyme -------------||-||||||||--||||||||||||----|||||||||||||||||||||||| 1 [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [L] COG0305 Replicative DNA helicase ||||----||--------||----------|----|----------|---|----------|---- 1 [P] COG0310 ABC-type Co2+ transport system, permease component |||||||||||||||--|---|----|||||--|||||------------||-------------- 1 [H] COG0311 Predicted glutamine amidotransferase involved in pyridoxine biosynthesis ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [R] COG0313 Predicted methyltransferases |||||||||-|||---|-||-|----|||-----||||----|||||-||||---|||||||||-- 1 [H] COG0314 Molybdopterin converting factor, large subunit |||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||-- 1 [H] COG0315 Molybdenum cofactor biosynthesis enzyme |-||||--|-|||||---||-|||--||||-||-||||----|||||-||||||||--|||||||| 1 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [R] COG0319 Predicted metal-dependent hydrolase --||---------|||||||||||||----||||||||----||||||||||||||---||||||| 1 [L] COG0323 DNA mismatch repair enzyme (predicted ATPase) -------------||-||||||||||||||||||||||----|||||||||||||||||||||||| 1 [J] COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase --|----------||-||||||----||||||||||||----||||||||||||||||||||||-- 1 [R] COG0325 Predicted enzyme with a TIM-barrel fold -------------|||--|||---|||||||----|||----|||||||||||--||||-|-|-|| 1 [O] COG0326 Molecular chaperone, HSP90 family ---|------|--||---||-|--|-||||----||||----|||||-|||||||||||||||||| 1 [L] COG0328 Ribonuclease HI |||||||||||||---|||||-||--||||||||||||----|||||||||||||||||||||||| 1 [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase -------------||-||||||||--||||||||||||----|||||-|||||||||||||||||| 1 [I] COG0331 (acyl-carrier-protein) S-malonyltransferase ----------------|-||||||---||-||||||||----|||||-|||||||||||||||||| 1 [I] COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III --|||||||-|||||--|||||||--|---|--|||||----|||||--|||-|||||--||-|-- 1 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0335 Ribosomal protein L19 ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0336 tRNA-(guanine-N1)-methyltransferase ----||-|--|||||--|||||||--||||||||||||----||||||||||||||||||||||-- 1 [E] COG0337 3-dehydroquinate synthetase -|--|||-----------|||---|-----|----|-|----|||||-|-||||--||-------| 1 [L] COG0338 Site-specific DNA methylase ||||--|||--|-||-|||||||||-||||||||||||----|||||-|||||||||||||||||| 1 [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase ||||--||-|------|||||||||||||||---||||-|--|||||-|||||||||||||||||| 1 [U] COG0341 Preprotein translocase subunit SecF ||||--||-|------|||||||||||||||---||||-|--|||||-|||||||||||||||||| 1 [U] COG0342 Preprotein translocase subunit SecD |||||||||||||-||||||||||-||---||||||||----|||||||||||||||||||||||| 1 [J] COG0343 Queuine/archaeosine tRNA-ribosyltransferase ----------------||||||--------|||||||||||||||||-||||-|||||||||||-- 1 [S] COG0344 Predicted membrane protein |||-----||------||||-|----|||-||---||-----|||||-||||||||---|||||-- 1 [E] COG0347 Nitrogen regulatory protein PII --|-|||||----||-|-||||----||||||-|||||----|||||-||||||||||||||||-- 1 [H] COG0352 Thiamine monophosphate synthase ----------------|-|||||||-||||||||||||||--|||||-|||||||||||||||||| 1 [L] COG0353 Recombinational DNA repair protein (RecF pathway) --|----------|--|||||-----|||||||||||||||||||||||||||||||||||||||| 1 [C] COG0356 F0F1-type ATP synthase, subunit a ----------------||||||--|||||||||||||||||||||||-|||||||||||||||||| 1 [M] COG0357 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division |||||||||||||---|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [L] COG0358 DNA primase (bacterial type) --------------|-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0359 Ribosomal protein L9 -------------||-|||||||||||||||||||||||||||||||||||||||||||-|||||| 1 [J] COG0360 Ribosomal protein S6 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0361 Translation initiation factor 1 (IF-1) -------------|||-|||--||||||||-|-||||-----|||||||-||-||----||||--- 1 [G] COG0362 6-phosphogluconate dehydrogenase -------------|||||||-||||||||--|-||||-----||||||||||||||||-|||||-- 1 [G] COG0364 Glucose-6-phosphate 1-dehydrogenase |||||||||||-||||----------||||||---|||----|||||-||--|-------|-|--- 1 [E] COG0367 Asparagine synthase (glutamine-hydrolyzing) |||||||||||||-----||||----|||-|----|-|----|||-|-||-----|---||||--- 1 [H] COG0368 Cobalamin-5-phosphate synthase |||---|||||-----||||-|--------||--||------|||||-||--|--||||----|-- 1 [P] COG0370 Fe2+ transport system protein B |||||||||||||-|--|||----------||||-|||----|||||-------------|----- 1 [C] COG0371 Glycerol dehydrogenase and related enzymes |-||||--|-|||||-||||-|----||||-|--||||----|||||-||-||||||||||||||| 1 [C] COG0372 Citrate synthase ||||||--|||||---|-||||||--|||||---||||----|||||-||-||||||||------- 1 [H] COG0373 Glutamyl-tRNA reductase ||||--||||||----|||||-----|||||----|||----|||||-||--||||||-||-||-- 1 [H] COG0379 Quinolinate synthase ||-|--||---------|||-|--------||-||||-----|||||-||-|-|||--|-----|| 1 [M] COG0381 UDP-N-acetylglucosamine 2-epimerase --||---------||---||||----|||-|----|||----|||-|-||-|---|---|||||-- 1 [R] COG0384 Predicted epimerase, PhzC/PhzF homolog -------------|||--|-|-----|---|||||||||---|||||--|--||||-------|-- 1 [O] COG0386 Glutathione peroxidase ||||----||---|--||||-|----||||||||||||----|||||-|--|-------------- 1 [S] COG0391 Uncharacterized conserved protein |||||||||--|-----|||-------|||-|---|-|----|||-|-|--|-----------|-- 1 [S] COG0393 Uncharacterized conserved protein |||||||||||||----|||-||||-||||||||||||----|||||-----|------|||||-- 1 [O] COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component --||---------||---||------|||-||||||||----|||---|-----------|--|-- 1 [S] COG0398 Uncharacterized conserved protein ---|||||---||||-||||-|-----|||----||||----|||||--|--|-||---|||||-- 1 [E] COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain ---|||||---||||-||||-|-----|||----||||----|||||--|--||||---|||||-- 1 [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase) --|-||-------||-|-||-|||--||||----||||----|||||-||-||||||||||||||| 1 [H] COG0407 Uroporphyrinogen-III decarboxylase ---|--||--|||||-||||-|----|||||---||||----||||||||--||||||||||||-- 1 [H] COG0413 Ketopantoate hydroxymethyltransferase -------------||-||||-|----|||||---||||----||||||||--||||||||||||-- 1 [H] COG0414 Panthothenate synthetase |-||-------|-|----||------|-----|-||------||||||||----|----|--||-- 1 [L] COG0415 Deoxyribodipyrimidine photolyase ----------------||||||||------|||||||||||||||||-||-|-|||||||||||-- 1 [I] COG0416 Fatty acid/phospholipid biosynthesis enzyme ||||||||||||||||||||||--||----||--|||-----|||||-||---------------- 1 [L] COG0419 ATPase involved in DNA repair ||||--||--||||||||-|-|---||||------|------|||-|--|---|||--|-|----- 1 [P] COG0428 Predicted divalent heavy-metal cations transporter ---|---------||---||-|----|||--|||||||--|||||||-||-|-|||---||-||-- 1 [R] COG0431 Predicted flavoprotein |||-----|--|-||-|-||-||||--||-||||||||----|||||-||||||||||||||||-- 1 [I] COG0439 Biotin carboxylase |||---||||--|||-||||-|----||||||-|||||----||||||||||-|||--||||||-- 1 [E] COG0440 Acetolactate synthase, small (regulatory) subunit |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0441 Threonyl-tRNA synthetase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0442 Prolyl-tRNA synthetase |-||||-------||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [O] COG0443 Molecular chaperone --|||||||-|||---||--||||-||---|||||||||||||||||-||||---||||||||--- 1 [EP] COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component -------------||-||||||||||----|||||||||||||||||||||||||||||||||||| 1 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division ---|----|---------||------||||-|--|||-----|||||-|-||-------------- 1 [H] COG0447 Dihydroxynaphthoic acid synthase |||-|||||-|||||||||||||||--|||-||-||||----||||||||-||--||||||||||| 1 [O] COG0450 Peroxiredoxin ||||||||||||-||-||||||---|||||||-|||||----|||||-||||||||||||||||-- 1 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases |||||||||||||||-||||||---|||||||||||||----|||||-||||||||||||||||-- 1 [H] COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase ||||||--||||-||-||||||----||||||||||||----||||||||-|||||||||||||-- 1 [EF] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) ||||||||||||||||||||||||||||||||||||||--|||||||||||||||||||||||||| 1 [O] COG0459 Chaperonin GroEL (HSP60 family) |||||||||||||||-||||-|----||||||-|||||----||||||||||||||||||||||-- 1 [E] COG0460 Homoserine dehydrogenase |||||||||||||||-||||||-|--||||||||||||----||||||||||||||||||||||-- 1 [F] COG0461 Orotate phosphoribosyltransferase -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [O] COG0465 ATP-dependent Zn proteases |||||||||||||||||||||||||||||||||||||||||||||||-|||||||||||||||||| 1 [L] COG0468 RecA/RadA recombinase -|||||||--||||||-|||||||-|||||||||||||||||||||||||||||||--||||||-- 1 [G] COG0469 Pyruvate kinase |||||||||||||||||||||||||-||||-||||||||||||||||||||||||||||||||||| 1 [L] COG0470 ATPase involved in DNA replication |||---||||||-||-||||-|----||||||--||||----||||||||||||||--|||||||| 1 [CE] COG0473 Isocitrate/isopropylmalate dehydrogenase |||-|||||-|||||-|-||-|---|-|||||--||||----|||||-|||-|||||||||||||| 1 [P] COG0475 Kef-type K+ transport systems, membrane components |-|||||||-|||||||-||||----|||||--|||||----|||||-||||||||||||||||-- 1 [H] COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0480 Translation elongation factors (GTPases) -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [M] COG0481 Membrane GTPase LepA -------------||-||||||||-||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain ||||--||||||||--||||-|---|||||-|||||||----|-||||||||||||--|||||||| 1 [G] COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family |-||||-------||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [O] COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain -------------||-||||||||||----|||||||||||||||||||||||||||||||||||| 1 [R] COG0486 Predicted GTPase ||||||||||||||||||||||----|||||--|||||----|||||-|||||||||||||||||| 1 [D] COG0489 ATPases involved in chromosome partitioning --|-||||--|-|||||||--|--|-||||||--||||----|||||-||--|--|--|||||||| 1 [ER] COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0495 Leucyl-tRNA synthetase ----------------|-||||--|-||||||||||||----|||||-|||||||||||||||||| 1 [L] COG0497 ATPase involved in DNA repair |||||||||||||||-||||-|----||||||-|||||----||||||||||||||||||||||-- 1 [E] COG0498 Threonine synthase |||||||||||||||||-||||----|||||-||-|||----||||||||||||||||||||||-- 1 [O] COG0501 Zn-dependent protease with chaperone function ||||||||||||||||||||-|||||||||||||||||||--|||||||||||||||||||||||| 1 [F] COG0504 CTP synthase (UTP-ammonia lyase) ||||||--||||-||-||||||----||||||||||||----||||||||-|||||||||||||-- 1 [EF] COG0505 Carbamoylphosphate synthase small subunit -|-----------||----|-|||-|-||-||||||||-|--|||||||||||||---|||||--- 1 [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member ---|||||---||||-||||-|||---|||--|-||||-|--|||||-||--||||---|||||-- 1 [E] COG0509 Glycine cleavage system H protein (lipoate-binding) -------------||-----|---|------|||||||-||||||||-|-|-----------|--- 1 [M] COG0510 Predicted choline kinase involved in LPS biosynthesis |||---|||--|-||-|||||||||-||||||||||||----|||||-||||||||||||||||-- 1 [I] COG0511 Biotin carboxyl carrier protein |||||||||||||||-||||||-|-|||||||||||||----|||||-||||||||||||||||-- 1 [F] COG0519 GMP synthase, PP-ATPase domain/subunit |-||--||-|-||-|--||||||||||||||||||||||||||||||-|||||--|||||||||-- 1 [E] COG0520 Selenocysteine lyase |||||||||||||---|--|-|----|||||---||||----|||||-||||---|||||||||-- 1 [H] COG0521 Molybdopterin biosynthesis enzymes |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0522 Ribosomal protein S4 and related proteins |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0525 Valyl-tRNA synthetase |||||||||||||---|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [F] COG0528 Uridylate kinase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0532 Translation initiation factor 2 (IF-2; GTPase) |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [O] COG0533 Metal-dependent proteases with possible chaperone activity -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [R] COG0536 Predicted GTPase |||||||||-|||||||-||||||-||||||||||||||||||||||||||||||||||||||||| 1 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases ---|||--|-|||||-||||-|-----||--|--||||----|||||--|-|---|||-|||||-- 1 [C] COG0538 Isocitrate dehydrogenases -------------||-||||||||||||||||||||||-|--|||||||||||||||||||||||| 1 [J] COG0539 Ribosomal protein S1 |||||||||||||||-||||||----||||||||||||----||||||||--||||||||||||-- 1 [F] COG0540 Aspartate carbamoyltransferase, catalytic chain |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [U] COG0541 Signal recognition particle GTPase |||-||||||-|-||-||--|---|-|||-||-|-|||----|||||-||---|||---|----|| 1 [HC] COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [O] COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) ||||||-||||||||-||||-|----||||||-|||||----||||||||||||||||||||||-- 1 [E] COG0547 Anthranilate phosphoribosyltransferase |||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||-| 1 [E] COG0548 Acetylglutamate kinase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [L] COG0550 Topoisomerase IA |||||||||--------|--|-|||-----|||||||||-|||||||||||||||||||------- 1 [L] COG0551 Zn-finger domain associated with topoisomerase type I |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [U] COG0552 Signal recognition particle GTPase ---|||-||--|||--||||||---|||||||||||||-||||||||-|||||--|---|||||-- 1 [C] COG0554 Glycerol kinase |-||------------|||||||||||||||||||||||||||||||-|||||||||||||||||| 1 [L] COG0556 Helicase subunit of the DNA excision repair complex ---|---------||||||||||||-|---||||||||||||||||||||||||||||||||||-- 1 [K] COG0557 Exoribonuclease R |-|||||||-|||||||||||-|||||||||||||||||||||||||-|||||||||||||||||| 1 [I] COG0558 Phosphatidylglycerophosphate synthase ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [K] COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) ||||--|||||-|---||||||--||-||---||||||-||||||||-||||-||---||||---- 1 [P] COG0569 K+ transport systems, NAD-binding component -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [K] COG0571 dsRNA-specific ribonuclease ---|---------||--|||-|-|||----|||||||||-|||||||-|-||-------------- 1 [F] COG0572 Uridine kinase ||||---||||||---||||-|---||||||||||||||-|||||||-|-|||--|--||||||-- 1 [P] COG0573 ABC-type phosphate transport system, permease component |||||||||||||||||||||||||||||||||||||||||||||||-|||||||||||||||||| 1 [I] COG0575 CDP-diglyceride synthetase |-||||-------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [O] COG0576 Molecular chaperone GrpE (heat shock protein) ---|||-----|-|||--|--|---|||||-|||||||----|||||-|||||--|---||||--- 1 [C] COG0578 Glycerol-3-phosphate dehydrogenase ||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||-- 1 [P] COG0581 ABC-type phosphate transport system, permease component ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [L] COG0587 DNA polymerase III, alpha subunit --|----------||-----|-||||||||||||||------||||||--||||||----||||-- 1 [G] COG0588 Phosphoglycerate mutase 1 --|----------||||-||-|||--||||||-|||||----||||||||||||||---||||||| 1 [FJ] COG0590 Cytosine/adenosine deaminases |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog) ----------------||||-||||||||||||||||||||||||||||||||||||||||||||| 1 [L] COG0593 ATPase involved in DNA replication initiation -----------------||||||||||||||||||||||||||||||||||||||||||-|||||| 1 [J] COG0594 RNase P protein component ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [MU] COG0597 Lipoprotein signal peptidase |||-||--||-|-||--||--|----|||--|---|||-------|---||-||||---|||||-- 1 [S] COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit ||||||||||||----|-|||---------||||||||----|||||-|||||||||||||||||| 1 [O] COG0602 Organic radical activating enzymes |-||||----|||||||-||-|||-|||||||||||||----|||||||||||||||||||||||| 1 [P] COG0605 Superoxide dismutase ||||||||||||----|||||||||||---||||||||----|||||-|||||||||||||||||| 1 [L] COG0608 Single-stranded DNA-specific exonuclease ||||---||----------|-----------||-||--|||-------||||||--|||-||-|-| 1 [V] COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases |||||||||||||||||--------------|--|||----------------------------| 1 [MI] COG0615 Cytidylyltransferase |||||||||-|-|---|||||||||-||||-----|||----|||||||||||||||||||||||| 1 [OU] COG0616 Periplasmic serine proteases (ClpP class) -------------|||||||||||||||||||||||||----|||||||||||||||||||||||| 1 [J] COG0617 tRNA nucleotidyltransferase/poly(A) polymerase -|||--|||||-|---||||||--|||||-||||||||||||------|----------------- 1 [R] COG0618 Exopolyphosphatase-related proteins ||||--|||||||||--|--|---|----|||||||||-||||||||-||---------------- 1 [R] COG0622 Predicted phosphoesterase ----------------|-||-|||---|||-|--||||----|||-||-|||-||||||||||||| 1 [I] COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH) -------------|----||------||||-|||||------|||||--|||-|||---|||||-- 1 [R] COG0627 Predicted esterase -----|-------||-|-||-|||--||||||||||||||||-------|--|--||--|--|--- 1 [T] COG0631 Serine/threonine protein phosphatase -----------------||||||||||||||||||||||||||||||-|||||||||||||||||| 1 [L] COG0632 Holliday junction resolvasome, DNA-binding subunit ----------------||--||----||||||-|||||||||||||||||||||||---|||||-- 1 [F] COG0634 Hypoxanthine-guanine phosphoribosyltransferase ----------------|||||||||||||-|||||||||---|||||||||||||||||||||||| 1 [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases -|||||||||||||||-|||||--------||-|-|||----||||||||||||||--|||-||-- 1 [T] COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases --||--|||--------|||-|--||----|----|||----|||||-||--|--||||||-||-- 1 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases -----------------|||||----|||||---||||----|||||-||-----|---|||||-- 1 [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain ---|--|||--||||-||--|-----|||--|||||||----|||||--|--------|||||||| 1 [G] COG0647 Predicted sugar phosphatases of the HAD superfamily ||||||||--||||||||----||---||||---|||||||||||||||----------------- 1 [L] COG0648 Endonuclease IV ||||-||||-|||----|||-|----|||-----||||----|||-|-||---------|||--|| 1 [CP] COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit |-||---------|||--||||--|-||||||||||||----|||||-||||||||||||||||-- 1 [O] COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family |||-----||-|-||-|---||-----||||--|||||----||-||-||--|--|---|||-|-| 1 [R] COG0655 Multimeric flavodoxin WrbA --|--|--|--|-||--|||-|--|-|||||||-||-|----|||||-||--|--|---||-||-- 1 [I] COG0657 Esterase/lipase ----------------|||||||||||||-|||||||||||||||||-||||||||||||||||-| 1 [R] COG0658 Predicted membrane metal-binding protein --|||||||-|||||-|-||-|||-|||||||||-|||----|||||-||||||||||||||||-- 1 [E] COG0665 Glycine/D-amino acid oxidases (deaminating) |||||||||||||-||||||||--|||||-||||||||----||||||||--|||||||||||||| 1 [M] COG0668 Small-conductance mechanosensitive channel ----------------||||||--||||||||||||||-|--||||||||||||||||||||||-- 1 [H] COG0669 Phosphopantetheine adenylyltransferase -------------||---||||||-|----|||||||--|--|||||-||||-||||||||||||| 1 [R] COG0670 Integral membrane protein, interacts with FtsH --------|---|||--||||---|---------|||-----||||---|-|-||---|--|--|| 1 [P] COG0672 High-affinity Fe2+/Pb2+ permease |||||||||||||||-|||||---|--||-||--||-|----|||||-|-------|||------- 1 [C] COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit ||-------|---||-|||||-----|---||--||||----||||--||-||--|--|||||||| 1 [R] COG0679 Predicted permeases ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [M] COG0682 Prolipoprotein diacylglyceryltransferase --|-||||--|||||-||||-|----|---||-|||||----||||||||||||||--||||||-- 1 [E] COG0685 5,10-methylenetetrahydrofolate reductase ------------------||-|-----|||-|--||||----------|-------||--|-||-- 1 [E] COG0686 Alanine dehydrogenase ---|----|-|-|----|||||--||----||||||--|||||||||-||||-|||---|||||-- 1 [E] COG0687 Spermidine/putrescine-binding periplasmic protein |---|||||||||||||--|||----||||-----|||----|||||-||||||||---||||||| 1 [J] COG0689 RNase PH ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [U] COG0690 Preprotein translocase subunit SecE ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [O] COG0691 tmRNA-binding protein ---|----|----||---||--||----------||||----|||||||||||---|||||||||| 1 [O] COG0694 Thioredoxin-like proteins and domains |-||----|----|||-|||-|----|||||||||||-----|||||-||||||||---||||||| 1 [O] COG0695 Glutaredoxin and related proteins --||-----------|--||----------|---|||||||||||||-||------||||------ 1 [G] COG0696 Phosphoglyceromutase |-|||||||-|||||||||||||||-|||-||-|||||----|||||||||||||||||||||||| 1 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily |||-----||------||||-------||-|-||-|||----|||-------------|------- 1 [R] COG0701 Predicted permeases --|----------||-||||||||--||||||||||||----||||||||||||||||||||||-- 1 [E] COG0703 Shikimate kinase |||||||||||||---||||-|---|||||||||||-||-|||||||-||--|--|---|||||-- 1 [P] COG0704 Phosphate uptake regulator -||||-|||||||||-||||-|--|-||||||||||||----|||||-|||||--|--||||||-- 1 [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid) --|------|-|----||||||||||||||||||||||----|||||||||||||||||||||||| 1 [M] COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase |-|-||--|--|-|||--||||--|||||-||||-||-----|||||-|||||||||||||||||| 1 [L] COG0708 Exonuclease III ||||||-|||||-||-|-----||-------||||||-----|||-|------||----------- 1 [E] COG0710 3-dehydroquinate dehydratase --|-------------|||||-----|||||||||||||||||||||||||||||||||||||||| 1 [C] COG0711 F0F1-type ATP synthase, subunit b -------------||-|||||-----|||||||||||||||||||||||||||||||||||||||| 1 [C] COG0712 F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) |||||||||||||---||||-|---||||||---||||----|||||-||--|--|---|||||-- 1 [R] COG0714 MoxR-like ATPases -----------------|||||||-||||||||||||||||||||||||||||||||||||||||| 1 [S] COG0718 Uncharacterized protein conserved in bacteria ||||----||-||---||||||||||||||||||||||--||-------|---||||||||||||| 1 [J] COG0721 Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit |||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||-- 1 [P] COG0725 ABC-type molybdate transport system, periplasmic component --|--|-|-|---|||-|||||||---|||||||||||----|||||-||--|--|||-|||||-- 1 [G] COG0726 Predicted xylanase/chitin deacetylase -|||--|||-------|---|-|||-|------|||||----------|-||-||-|||------- 1 [R] COG0733 Na+-dependent transporters of the SNF family -------------||-||--|||||||||||||||||||||||||||||----||||||||||||| 1 [I] COG0736 Phosphopantetheinyl transferase (holo-ACP synthase) ----------------||||----||----||||-|||----|||||||||||||||||||||||| 1 [M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) -----------------|||||||||||||||||||||-|--|||||||||||||||||||||||| 1 [L] COG0742 N6-adenine-specific methylase ----------------|||||||||-|||||----|||----|||||||||||||||||||--|-- 1 [I] COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase |||||||||||||---|-||-|----|||-----||||----|||||-||||--||||||||||-- 1 [H] COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A --|||||||-|||---||||||||--|||||||-||||----|||||-||||---||||||||--- 1 [E] COG0747 ABC-type dipeptide transport system, periplasmic component -------------|--||||||||||||||||||||||----|||||-|||||||||||||||||| 1 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains |||||||||||||---||||||||||||||||||||||----|||||-|||||||||||||||||| 1 [M] COG0750 Predicted membrane-associated Zn-dependent proteases 1 ----------------|||||-||-------|||-|||----|||||||||||||||||||||||| 1 [J] COG0751 Glycyl-tRNA synthetase, beta subunit ----------------|||||-||-------|||-|||----|||||||||||||||||||||||| 1 [J] COG0752 Glycyl-tRNA synthetase, alpha subunit -------------||------|----|-------||||----|||||-||||-||||||||||--- 1 [P] COG0753 Catalase -------------||||---|-|||-||||||||-||-----||||||-|||||||||-||||||| 1 [F] COG0756 dUTPase ----------------||||||--|||||-|-||||||||--|||||-||||||||||||||||-| 1 [LU] COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake ----------------||||||||||-||-||||||||----|---|-|||||||||||||||||- 1 [S] COG0759 Uncharacterized conserved protein -----------------||||-||||||||||||||||----|||||-||||---||||||-||-- 1 [S] COG0762 Predicted integral membrane protein ----------------||||||||------||||||||----|||||||||||||||||||||||| 1 [I] COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases |--------|------||||||||||||||||||||||----|||||||||||||||||||||||| 1 [M] COG0769 UDP-N-acetylmuramyl tripeptide synthase |||------|------||||||||||||||||||||||----|||||||||||||||||||||||| 1 [M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase |--------|------||||||||||||||||||||||----|||||||||||||||||||||||| 1 [M] COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase ----------------||||||||||||||||||||||----|||||||||||||||||||||||| 1 [M] COG0773 UDP-N-acetylmuramate-alanine ligase --|--------------|--|||||||||-||||||||||--||||||||||-|||||||||||-- 1 [F] COG0775 Nucleoside phosphorylase ----||----------||||||||||-||||||||||||||||||||||||||||||||||||||| 1 [L] COG0776 Bacterial nucleoid DNA-binding protein ----------------|-||||||--|||-||||||||----|||||-||||||||||||||||-- 1 [I] COG0777 Acetyl-CoA carboxylase beta subunit ----------------||||||--|||||-||||||||----|||||-|||||||||||||||||| 1 [S] COG0779 Uncharacterized protein conserved in bacteria ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [K] COG0781 Transcription termination factor -----------------|---||||||||||||||||||||||||||||||||||||||||||||| 1 [K] COG0782 Transcription elongation factor ---|--------------||||--|||----|||||||-|--|||||-|||||--|||||-|-||| 1 [P] COG0783 DNA-binding ferritin-like protein (oxidative damage protectant) --------------|-|-||||--||||||||||||||----|||||-|||||||||||||||||| 1 [M] COG0787 Alanine racemase ----||----||----||||||||||----|---||||----|||||-|||||||||||||||||| 1 [M] COG0793 Periplasmic protease |||---|||||||---|---|-||------|---|||-----|||||-|||||||||||||||||| 1 [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation ----------------|-||||--||||||||||||||----||||||||||-|||||||||||-- 1 [M] COG0796 Glutamate racemase ----------------||||-|||||||||-|||||||----|||||-|||||||||||||||||| 1 [S] COG0799 Uncharacterized homolog of plant Iojap protein -------------||-||||||||--||||||||||||----|||||-||||||||||||||||-| 1 [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase ----------------||||||||||||||||||||||-|--|||||-|||||||||||||||||| 1 [R] COG0802 Predicted ATPase or kinase --||||--|-|||---|-||-|----||||----||||----|||||-|||||||||||||||||| 1 [U] COG0805 Sec-independent protein secretion pathway component TatC ----------------||||||--||||||||||||||----|||||||||||||||||||||||| 1 [J] COG0806 RimM protein, required for 16S rRNA processing ----------------||||||---|----||||||||----|||||||||||||||||||||||| 1 [J] COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) ----------------||||||||||||||||||||||----|||||||||||||||||||||||| 1 [M] COG0812 UDP-N-acetylmuramate dehydrogenase -----------|--------||--|------||||||-|||||||||||-||----||----|--- 1 [F] COG0813 Purine-nucleoside phosphorylase ----------------||||||||--|||||||-|||||||||||||||||||||||||||||||| 1 [L] COG0816 Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) -----------------|||-|--------||||||||----|||||-|||||||||||||||--- 1 [M] COG0818 Diacylglycerol kinase ----||||--|||||----|------|----|-|||||------------||----|||--|---- 1 [K] COG0819 Putative transcription activator ----------------||||||--|-|||-|||||||||---||||||||||||||||||||||-- 1 [R] COG0820 Predicted Fe-S-cluster redox enzyme --||----|----|||||-||-||||||||||||||||||||||||||||||-||||||||||||| 1 [C] COG0822 NifU homolog involved in Fe-S cluster formation |-||||----|||---|-||||--|-|||-|---||||----|||||-||||||||||||||||-- 1 [R] COG0824 Predicted thioesterase ----------------|-||||||--|||-||||||||----|||||-||||||||||||||||-- 1 [I] COG0825 Acetyl-CoA carboxylase alpha subunit ----------------|-||--||||----|||||||||-|||||||||||||||||||||||||| 1 [J] COG0828 Ribosomal protein S21 -------------||---------------||--|||-----|||||--|-----|||-------- 1 [E] COG0833 Amino acid transporters --||--|||--------|||----||----|----|||----|||||-||--|--||||||-||-- 1 [NT] COG0835 Chemotaxis signal transduction protein ---|------||||--|-||-|----||||----||||----||||||-|--|--|---||||||| 1 [C] COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1 ------||||||||||||--||----|||||-|-||||-|--|||||-||-|---||||----|-- 1 [K] COG0846 NAD-dependent protein deacetylases, SIR2 family ----|---|----||||||--||||-|||-||||||||----|||||||||||||||||||||||| 1 [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases ---------|------||--||--||----||||||||----|||||||||||||||||||||||| 1 [D] COG0849 Actin-like ATPase involved in cell division ----------------||||||--------|----|||----||||||||-|||||||-||||--- 1 [D] COG0850 Septum formation inhibitor ----------------||||-|----|||||---||||----|||||--|--||||||||--||-- 1 [H] COG0853 Aspartate 1-decarboxylase ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0858 Ribosome-binding factor A ||||--|||||||-----------------|----|||----|||-|---------||---|-|-- 1 [K] COG0864 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain |||-----||-----------|---|----|----|||----|||--------------||||--- 1 [F] COG1001 Adenine deaminase ---|||||---||||-||||-|-----|||----||||----|||||--|--|-||---|||||-- 1 [E] COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain ||||--||---------|||-|----|-------||||----------||---------|||--|| 1 [P] COG1006 Multisubunit Na+/H+ antiporter, MnhC subunit --||||-||-|||---|-||-|----|||-----||||----||||||||--|||||||||||||| 1 [CP] COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit ||||||--||||------|||------||-|----|----------|--|-----|---||||--- 1 [H] COG1010 Precorrin-3B methylase |||||||||||||||-|||||---|--||-||--||-|----|||||-|-------|||------- 1 [C] COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit |||||||||||||---|||||---|--||-||--||-|----|||||-|------||||---||-- 1 [C] COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit -----------------|---|--------||||||||-|--|||||||-------||-||-|--- 1 [G] COG1015 Phosphopentomutase -------------||----|------||||-||||||-----|||||-||-----|--||-||--- 1 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins -------------||-----------|||-||--||||---------------------||||--- 1 [C] COG1038 Pyruvate carboxylase ----------------|-----||-------||||||-||||------------------------ 1 [L] COG1039 Ribonuclease HIII --||----------|--|||------||||||||||||----||||||||||-|||||||||||-- 1 [E] COG1045 Serine acetyltransferase --||||----|||||-|----|----||||||--|||-----|||||-||--||||---||||||| 1 [C] COG1048 Aconitase A ----||||--|||||-|-|||---|-----|-|-||||----|||||-||||-|||||||||||-- 1 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases ||-|||--|||||||-||||||||--||||||--||||----|||||-|||||||||||||||||| 1 [C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit ------------------||-|||--|----||||||-----||||||||--|--|---||||||| 1 [R] COG1054 Predicted sulfurtransferase ----|||||-|||----||||-||---|||----||||----||||--||---|||--||--|--- 1 [P] COG1055 Na+/H+ antiporter NhaD and related arsenite permeases -------------||-|||||---||||||||||||||||||||||||||--||||||||||||-- 1 [H] COG1057 Nicotinic acid mononucleotide adenylyltransferase ---||||||-||||---|||||-----||||-||||||----|||||-|----|||---|||||-- 1 [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA --|||||||-||||||---|||--|-|||||-||||------|||||-|----------------- 1 [KL] COG1061 DNA or RNA helicases of superfamily II ----------------|||||||||-|||-|||-||||----|||||-|||||||||||||||||| 1 [O] COG1066 Predicted ATP-dependent serine protease -----|-------||-----------||||-|||-|||----|||||-|-||-------||||--- 1 [H] COG1072 Panthothenate kinase --------------------|-||||-||-||||||||----|||||||||||||||||||||||| 1 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) |||||||||||||--|||--|----------||||||||-||------------------------ 1 [R] COG1078 HD superfamily phosphohydrolases ---|--|||-|-|----|-|-|--||----||||-||-||||-------|-----|---||||--- 1 [R] COG1079 Uncharacterized ABC-type transport system, permease component --------------------||||-||---||||||||-|||||||||||||||||------||-- 1 [G] COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) |------------||-|-||||----|---||-|-|||--|||||||-||||-|||||||||||-- 1 [M] COG1087 UDP-glucose 4-epimerase ----||------------||------||||----||||----|||||--||||------------- 1 [R] COG1090 Predicted nucleoside-diphosphate sugar epimerase -|----||-|--|---||--||||-------||||||-----||||||||||||||---||||--- 1 [R] COG1092 Predicted SAM-dependent methyltransferases --------------------------|||||||-||||----|||||--|---------|-|---- 1 [E] COG1113 Gamma-aminobutyrate permease and related permeases --|----------||------|----||||-|--||||----|||||----|-------------- 1 [P] COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA --|-----|-------|-||------|||||||-||||--------|-||-||||---|-|||||| 1 [GM] COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component |--|---||-|-|----|||-------||-||||||||---------------------------- 1 [C] COG1141 Ferredoxin ----------------|||||||||-||||||---|||----||||||||||||||||||||||-- 1 [HI] COG1154 Deoxyxylulose-5-phosphate synthase ----------------||----||||----|----|||----||||||||-----|||||||||-- 1 [NU] COG1157 Flagellar biosynthesis/type III secretory pathway ATPase ----------------||--|||||||||||---||||----|||||||||||||||||||||||| 1 [K] COG1158 Transcription termination factor ----------------||||||--|||||||||||||||||||||||||||||||||||||||||| 1 [R] COG1159 GTPase ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [R] COG1160 Predicted GTPases ---|--------------||------||||-|--|||-----|||||-|-||-------------- 1 [H] COG1165 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase ----||||--|||||--|-|||----|||||-||||||----|||||-||-|---|---|||||-- 1 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs --------------------||----||||||-|-|||----|||||---|----|---------- 1 [E] COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities ---|--------------||------||||-|--|||-----|||||-||||---------|---- 1 [HQ] COG1169 Isochorismate synthase ---|||----|||||--|||||----||||-|-|||||----|||||-||||||||--|||||||| 1 [E] COG1171 Threonine dehydratase ---|----|-|-|----|-|||--||----||||||--|||||||||-||||-|||---|||||-- 1 [E] COG1176 ABC-type spermidine/putrescine transport system, permease component I ---|----|-|-|----|-|||--||----||||||--|||||||||-||||-|||--||||||-- 1 [E] COG1177 ABC-type spermidine/putrescine transport system, permease component II |||-|||||||||---||--|------||-||||||------|||||-||||---|---------- 1 [O] COG1180 Pyruvate-formate lyase-activating enzyme -------------||-||||||||||||||||||||||----|||||||||||||||||||||||| 1 [J] COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) -------------||-|||||||||||||||||-||||----|||||||||||||||||||||||| 1 [J] COG1186 Protein chain release factor B -----------------|--|-----|---||||||||----|||||-||||-|||||||||||-- 1 [J] COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) --|-----|-------|||||----|||||||||-|||||----------------|||||||||| 1 [J] COG1189 Predicted rRNA methylase --|-------||-|||||||||||--|||||||||||||||||||||||||||||||||||----- 1 [J] COG1190 Lysyl-tRNA synthetase (class II) ----------------||||--|||--||-|---||||----|||||-||-----||||------- 1 [K] COG1191 DNA-directed RNA polymerase specialized sigma subunit |-||--||--------||||||---|----||||||||------------------|||------- 1 [L] COG1193 Mismatch repair ATPase (MutS family) |--|------|-|-|------||||-||||||||||||----||||||||||||||||||||||-- 1 [L] COG1194 A/G-specific DNA glycosylase ----------|-------|||||-|-||||||||||||----|||||-|||||------||||||| 1 [L] COG1195 Recombinational DNA repair ATPase (RecF pathway) -||||||||----|||||||||--||||||||||||||||||-------|--|||----|||||-- 1 [D] COG1196 Chromosome segregation ATPases -----------------|||||||||||||||||||||----|||||||||||||||||||||||| 1 [LK] COG1197 Transcription-repair coupling factor (superfamily II helicase) ----------------||||||||||||||||||||||----|||||||||||||||||||||||| 1 [L] COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase ----------------||||||--||||||||||||||----|||||-|||||||||||||||||| 1 [LK] COG1200 RecG-like helicase ----------------||||||---------|||||||---------------------|||||-- 1 [J] COG1206 NAD(FAD)-utilizing enzyme possibly involved in translation ----------------||||||----||||||||||||----|||||||||||||||||||||||| 1 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) |||----|---|----|--||----|||||||||||||--|||||||-||||||||||||||||-- 1 [M] COG1210 UDP-glucose pyrophosphorylase ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [O] COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone |-|-||||||||-||||-||------|---|||-||||----|||||--|-----|---|||||-| 1 [M] COG1215 Glycosyltransferases, probably involved in cell wall biogenesis ------------------||||----||||||||||||----|||||||||||||||||||||||| 1 [T] COG1217 Predicted membrane GTPase involved in stress response -------------|--||||||||||||||||||||||----|||||||||||||||||||||||| 1 [O] COG1219 ATP-dependent protease Clp, ATPase subunit ----------------||-------|--------||||----|||||||||||--||||||||||| 1 [O] COG1220 ATP-dependent protease HslVU (ClpYQ), ATPase subunit ||||||||||-|||--||||-|----|||-||---|||||--|||||-|||-|||||||||||||| 1 [P] COG1226 Kef-type K+ transport systems, predicted NAD-binding component -|------|----|||-|--||--------|||||||-----------|----------------- 1 [C] COG1227 Inorganic pyrophosphatase/exopolyphosphatase --|---|---||-|||||-|-|----|--||||||||-----|||||--|-|||||--||||||-- 1 [P] COG1230 Co/Zn/Cd efflux system component --||--|-|-|--||-|----|||--||||----||||-------|---------|-------|-- 1 [H] COG1232 Protoporphyrinogen oxidase ||||-------||-----||-|----|||-----||-|-----------------|------||-- 1 [Q] COG1233 Phytoene dehydrogenase and related proteins -|-------|------||--|---------|||-||||----|||||-|----------------- 1 [R] COG1242 Predicted Fe-S oxidoreductase --|-------|-|-----||-|----|---||-|||||----|||-|-||-----|---|||||-- 1 [M] COG1247 Sortase and related acyltransferases -||-|||||-|||----|-|-|---|--|-||||||||----|||||-||-|---|----|-|--- 1 [C] COG1254 Acylphosphatases ----------------||------||----|----|||----||||||||-----|||||||||-- 1 [N] COG1256 Flagellar hook-associated protein ||||||||||||||||---------|-----|||||------------|----------------- 1 [I] COG1257 Hydroxymethylglutaryl-CoA reductase |||---||-||-|---|---|-----------|--|||----|||||-||||-||||||-----|| 1 [I] COG1267 Phosphatidylglycerophosphatase A and related proteins |-||--|||--------||||||-|-|---||||||||---------------------||||-|| 1 [R] COG1268 Uncharacterized conserved protein |||||||||||||-----||||-----||-|----|-|--------|-||-----|---||||--- 1 [H] COG1270 Cobalamin biosynthesis protein CobD/CbiB --||||--|-------|-||--||--|||--|--||||----|||||-||||---|--|||||||| 1 [C] COG1271 Cytochrome bd-type quinol oxidase, subunit 1 -------------|||----||--|||||-||||||||----|||||-||--|||----|||||-- 1 [R] COG1272 Predicted membrane protein, hemolysin III homolog ----------------|----|-------------|||----|||||--------|----|-|--- 1 [P] COG1276 Putative copper export protein ----------------||||||--------||||||||-|--|||||-||||||||---|||||-- 1 [O] COG1281 Disulfide bond chaperones of the HSP33 family ----------------|-||||--|--||-||-|-|||----|||||--|||---|---|||---- 1 [S] COG1285 Uncharacterized membrane protein ------------------------||-----|||||||----|||||-|||||||||||||||||| 1 [R] COG1286 Uncharacterized membrane protein, required for colicin V production ------------------|--|------------|||-----|||||-||||||||--|||||--- 1 [S] COG1289 Predicted membrane protein ----------------||------||----|----|||----|||||-||-----|||||||||-- 1 [N] COG1291 Flagellar motor component ---|--------------------|-|||-----||||----|||||-||||-||-----|----- 1 [M] COG1292 Choline-glycine betaine transporter ||||||||||||||||-|||||---|----||||||||------------------|||------- 1 [K] COG1293 Predicted RNA-binding protein homologous to eukaryotic snRNP --||------------|-||--||--|||--|--||||----|||||-||||---|--|||||||| 1 [C] COG1294 Cytochrome bd-type quinol oxidase, subunit 2 --|-------------|-||||||--||||||||||||-|--|||||-|||||||||||||||||| 1 [S] COG1295 Predicted membrane protein --|-----|-----------||----|----|-|||||----|||||-||||-|||||-||||--- 1 [E] COG1296 Predicted branched-chain amino acid permease (azaleucine resistance) ----------------||----||||----|----|||----||||||||-----|||||||||-- 1 [NU] COG1298 Flagellar biosynthesis pathway, component FlhA |||||||||||||||---||-|--||||||-||||||-----|||||-||||-||----||||||| 1 [C] COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases ----------------|-|||||||||||||||||||||-|-|||||||||||||||||||||||| 1 [U] COG1314 Preprotein translocase subunit SecG ||||--||---------|---|----|-------||||----------||---------|||--|| 1 [P] COG1320 Multisubunit Na+/H+ antiporter, MnhG subunit |||||||||||||----|---||||-||||||||||||----|||-|-----|---------|--- 1 [K] COG1321 Mn-dependent transcriptional regulator ||-------|-------|--|---------||||||||-|-------------------------- 1 [R] COG1323 Predicted nucleotidyltransferase -----------------||-||||--||||||||||||----|||||-||||||||---|||||-- 1 [K] COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains |||---||-|-------|--|---------||||||------|||||-||||---|---------- 1 [F] COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase ----------------||----||||----|----|||----||||||||-----|||||||||-- 1 [NU] COG1338 Flagellar biosynthesis pathway, component FliP ----------------||------||----|----|||----|||||-||-----||||------- 1 [N] COG1345 Flagellar capping protein --||--|||--------|-|----||----|----|||----|||||-||-----|--|||-||-- 1 [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins -||||||||-------||||||--|-||||||||||||||||-------|--||||---|||||-- 1 [S] COG1354 Uncharacterized conserved protein --||--------------||-|--|-|||-||---|||----|||||--|-|-------||-|||| 1 [S] COG1357 Uncharacterized low-complexity proteins ||||||||||||||||-|--|---------||||||||---------------------------- 1 [J] COG1358 Ribosomal protein HS6-type (S12/L30/L7a) ----------------||------||----|----|||----|||||-||-----|||||||||-- 1 [N] COG1360 Flagellar motor protein |||-----||---||-||||-|----||||||--||||-----------|---|||---|||||-- 1 [E] COG1364 N-acetylglutamate synthase (N-acetylornithine aminotransferase) -||-|-||--||-----|--|------||----|-|--------------|-----|||---|--| 1 [R] COG1373 Predicted ATPase (AAA+ superfamily) ----------------||----||||----|----|||----||||||||-----|||||||||-- 1 [NU] COG1377 Flagellar biosynthesis pathway, component FlhB ------------------|||||||-||||||||||||||--|||||-||||||||---||||||| 1 [L] COG1381 Recombinational DNA repair protein (RecF pathway) ----------------||||||--||||||||||||||||--|||||||||||||||||||||||| 1 [S] COG1385 Uncharacterized protein conserved in bacteria --|-|||||--------|||||--|-||||||||||||||||-------|--||||---|||||-- 1 [K] COG1386 Predicted transcriptional regulator containing the HTH domain |||---|||--|-----|---|||------|---|||-----------||||---|---||-|--- 1 [P] COG1392 Phosphate transport regulator (distant homolog of PhoU) ----------------||||-|----||||||||||||----|||||-||||||||---------- 1 [R] COG1399 Predicted metal-binding, possibly nucleic acid-binding protein ||-|-----||||----|||-------||------|-|---------------------|||||-- 1 [R] COG1402 Uncharacterized protein, putative amidase ---|--------------||-|-----||||||-|||-----|||---|---|--|---|||||-- 1 [V] COG1403 Restriction endonuclease |-|---|||||-|||-|-||--||--||||||--|||-----|||||-||||---|---|||||-- 1 [R] COG1409 Predicted phosphohydrolases ----------------||------||----|----|||----------||-----||||------- 1 [N] COG1419 Flagellar GTP-binding protein -----------------||||-||--||||||||||||||||----------|--|||||||||-- 1 [K] COG1420 Transcriptional regulator of heat shock gene -----------------|-|--||||-----|||||||----|||||-|||||--|--------|| 1 [S] COG1426 Uncharacterized protein conserved in bacteria ---------------------|---|-----||-|||-||||-------------|---------- 1 [F] COG1428 Deoxynucleoside kinases ---||-----|----|-|---|---|----|||||||||||||||||-|-||-------||-|--- 1 [F] COG1435 Thymidine kinase -----------------|---|-|--||||||||||||----|||||-|-||-------------- 1 [K] COG1438 Arginine repressor ----||||---|-|---------------------|||----|||-|--|-|-||----------- 1 [F] COG1457 Purine-cytosine permease and related proteins ----------------||||||||------||||||||----|||||-||||||||------||-- 1 [NU] COG1459 Type II secretory pathway, component PulF ----------------||||-||||||||||||||||||||||||||||||||||||||||||||| 1 [L] COG1466 DNA polymerase III, delta subunit -----------|--|--|||-|---|||||||---|||----|||||-||||||||---||||||| 1 [G] COG1472 Beta-glucosidase-related glycosidases ||||---||----------|-|--------||||||||-----------|-------------|-- 1 [K] COG1476 Predicted transcriptional regulators --|-------------||--|||||-----||||-|------|||||-||||||||----||||-- 1 [H] COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis -----------------||||--||-----|----|||---------------------------- 1 [R] COG1480 Predicted membrane-associated HD superfamily hydrolase -----------------|--|-----||||||||||||||||------------------------ 1 [S] COG1481 Uncharacterized protein conserved in bacteria --------|----||--|---|---|||||||||||||-|--|||||-|--|-------------- 1 [G] COG1482 Phosphomannose isomerase --|||||||||||||-||||||--|||||-||||||||||||||||||||-|||||--|||||--- 1 [H] COG1488 Nicotinic acid phosphoribosyltransferase -------------||-||--||----|||-||||||||----|||||-||||-|||---------- 1 [J] COG1490 D-Tyr-tRNAtyr deacylase ||||||--||-|------||||-----||-|----|-|--------|-||-----|---|||||-- 1 [H] COG1492 Cobyric acid synthase ---------|----------|---|-----||||||||||||----------||||---|||||-- 1 [T] COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism ----------------|-----||||----|----|||----|||||-||--||||||||||||-- 1 [K] COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog ----------------||------||----|----|||----|||||-||-----||||------- 1 [NUO] COG1516 Flagellin-specific chaperone FliS |||-|||-|||||---||-||------||---|--|-|----|||||----|--|---|------- 1 [L] COG1518 Uncharacterized protein predicted to be involved in DNA repair ----------------||||||--||-||||----|||-|---------|--|||||||----|-- 1 [K] COG1521 Putative transcriptional regulator, homolog of Bvg accessory factor ----|||||--|-|||-|-|------|---|----|-|-----------|--|-----|-|-||-- 1 [R] COG1524 Uncharacterized proteins of the AP superfamily |||-||--|-||--------------|||-----||||----|||||-||||---|--||||||-- 1 [C] COG1526 Uncharacterized protein required for formate dehydrogenase activity ---|--||-||||---|||||-||--|||||----|-|----||||||||||||||---||||||| 1 [J] COG1530 Ribonucleases G and E ||||--||||-||-------|---------||||||||----|||||-||||||||---------- 1 [J] COG1534 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein ----------------||----||||----|----|||----||||||||-----|||||||||-- 1 [N] COG1536 Flagellar motor switch protein -------------||---||||||--||||||||||||----|||||-||||||||||||||||-- 1 [H] COG1539 Dihydroneopterin aldolase ----------------||||||-|-|||||||||||||----|||||-|||||--|---||||||| 1 [J] COG1544 Ribosome-associated protein Y (PSrp-1) ---|------------||||||----|||||-||-||||||||||||-||--||||||||||||-- 1 [R] COG1546 Uncharacterized protein (competence- and mitomycin-induced) -----------------|---|-----||||----|||---------------------------- 1 [S] COG1550 Uncharacterized protein conserved in bacteria ----------------||------||----|----|||----||||||||-----|||||||||-- 1 [N] COG1558 Flagellar basal body rod protein ----------------|---||--||||||||||-|||----|||||-|||||||||||||||||| 1 [R] COG1559 Predicted periplasmic solute-binding protein ----------------||--|----|----|----|||----|||||-||||||||---|||||-- 1 [S] COG1561 Uncharacterized stress-induced protein -------------||--|--||--|-----|||||||-------------------||-||||--- 1 [H] COG1564 Thiamine pyrophosphokinase -----------------|-|||||--||||||||||||----|||||-|||||||||||||||||| 1 [L] COG1570 Exonuclease VII, large subunit --||||||----|---||--||-----||------|||--------|--|-----|---|||||-- 1 [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold -----------------|--||--------||||||||||--|||||-||||||||||||||||-- 1 [S] COG1576 Uncharacterized conserved protein ------------------||-|--||||||||||||||----|||||-||||||||---||||||| 1 [M] COG1589 Cell division septal protein |-|-----|---------||-|--------|-|-||||----|||||-||-----|---|||||-- 1 [C] COG1600 Uncharacterized Fe-S protein ||||||--|||||||-||--||----||||||||||||----||||||||||||||||||||||-- 1 [E] COG1605 Chorismate mutase ---|||----|||--------|||--|-------||||----||||||||||-|||||||||||-- 1 [I] COG1607 Acyl-CoA hydrolase -------------|---|--------|||-|----|||----------||--||||--|||||--- 1 [S] COG1610 Uncharacterized conserved protein ---|--------|||-|-||-|----||||----||||-----------|--|--|---||||||| 1 [O] COG1612 Uncharacterized protein required for cytochrome oxidase assembly ---|----|-||||--|-||-|----||||----||||----||||||-|--|--|---||||||| 1 [C] COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2 -|||--||||------|-||-|||||----||||||||-|||------------------------ 1 [S] COG1624 Uncharacterized conserved protein |||||||||||||---------------------||||---------------------------- 1 [R] COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold ||||||--|||-|||-|---|------||-|---||||----||||||||--|||----|||||-- 1 [H] COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) ---|----|-|-----|-||-|||--||||----|||-----|||||-|||||||||||||||||| 1 [O] COG1651 Protein-disulfide isomerase -------------------|-|--||---------||-----|||-|-||-|||||---|||||-- 1 [S] COG1652 Uncharacterized protein containing LysM domain --||---||------------|--------||||||||----|||||-|||||------------- 1 [K] COG1654 Biotin operon repressor |||-|||||-------|---|----|----|||||||||-||------------------------ 1 [L] COG1658 Small primase-like proteins (Toprim domain) --------------------||----||||||||||||----|||||-||||||||---------- 1 [R] COG1660 Predicted P-loop-containing kinase ||||--|||-|||----|---|--------||-|||||--------------|----------|-- 1 [CP] COG1668 ABC-type Na+ efflux pump, permease component ------------------------||----|---||||----|||||-||---------|||||-- 1 [S] COG1671 Uncharacterized protein conserved in bacteria ----------------||------||----|----|||----||||||||-----|||||||||-- 1 [NU] COG1677 Flagellar hook-basal body protein --|-----|-------|-||------|||||||-||||--------|-||-||||---|-|||||| 1 [GM] COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component |-|-------------||--|---------|----|||--------|-||-----|---||-|--- 1 [S] COG1683 Uncharacterized conserved protein ----------------||------||----|----|||----||||||||-----|||||||||-- 1 [NU] COG1684 Flagellar biosynthesis pathway, component FliR ----------------|---||---|--------||||||||-----------------|||||-- 1 [S] COG1692 Uncharacterized protein conserved in bacteria -------------||----||---|-----|||||||------------|---||-|-|-|----- 1 [M] COG1696 Predicted membrane protein involved in D-alanine export ---------||-|---||||-|----||||-|||||||----|||||-||-|||||---|||||-- 1 [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase -||--------------|--|---|-------||-|--||---|||---|-|---|---|||||-- 1 [S] COG1704 Uncharacterized conserved protein -----------------||-||--|-----||||||||||||------------------------ 1 [H] COG1713 Predicted HD superfamily hydrolase involved in NAD metabolism |--------|--------||-------||||----|||----------|||--||||||||||||| 1 [S] COG1714 Predicted membrane protein/domain --|||||||-|-|---||||-|---|-|||-----|||----------||-----|---|||||-- 1 [R] COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) -----------------|-|||----||||||||||||----|||||-|||||||||||||||||| 1 [L] COG1722 Exonuclease VII small subunit -----------|---------|-----||------|-|-||-|---|------------|--|--- 1 [R] COG1735 Predicted metal-dependent hydrolase with the TIM-barrel fold --||---------||--|--||---||---||||||||||--|||-|-||||-|||||||||---- 1 [S] COG1739 Uncharacterized conserved protein ---|--|||-|-|----|-|-|--||----||||-|||||||-------|-----|---||||--- 1 [R] COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein ----------------|-------||----|----|------||||||||-----|||||||||-- 1 [N] COG1749 Flagellar hook protein FlgE ||||||||||||||||||||-|--||||||||||||||----|||||-|||||||||||||||||| 1 [K] COG1758 DNA-directed RNA polymerase, subunit K/omega |||||-|||||||---|-----------------||||----|||||-|-||---|--|||||--- 1 [H] COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein ----||---------------|----|----|--|||---|||||-|-||--|--|---|||||-- 1 [O] COG1764 Predicted redox protein, regulator of disulfide bond formation ----------------||------||----|----|||----||||||||-----|||||||||-- 1 [NU] COG1766 Flagellar biosynthesis/type III secretory pathway lipoprotein -------------|||||--||--|-----||--||||---------------------------- 1 [S] COG1774 Uncharacterized homolog of PSP1 --||--|||--------|------|-----|----|||----------|-------|||------- 1 [NT] COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation ----------------|--||-||||----||-|||||----|||||-|||||--||||----||| 1 [M] COG1792 Cell shape-determining protein |-|-||-------||-|----|------------||||---------------------------- 1 [L] COG1796 DNA polymerase IV (family X) ||||||--||||------||||-----||-|----|-|--------|--|-----|---||||--- 1 [H] COG1797 Cobyrinic acid a,c-diamide synthase ------------------|||-----||||||||||||---------------------------- 1 [S] COG1799 Uncharacterized protein conserved in bacteria --|-|||||-|||---||-|-|------------||||----|||||-||-|---|---||-||-- 1 [S] COG1801 Uncharacterized conserved protein -----------------||------|----|----|||----|||||-|-||---|---|||---- 1 [G] COG1803 Methylglyoxal synthase --------|--------|--||--------|----|||----|||-|------------------- 1 [R] COG1811 Uncharacterized membrane protein, possible Na+ channel or pump ----------------||------||----|----|||----||||||||-----|||||||||-- 1 [N] COG1815 Flagellar basal body protein ----------------||||-|||||||||----||||----|||||||||||||||||||||||| 1 [J] COG1825 Ribosomal protein L25 (general stress protein Ctc) --||||--|||||---|-||-|----||||----||||----|||||-|||||||||||||||||| 1 [U] COG1826 Sec-independent protein secretion pathway components |--------|-------|--|---------|-||-|||---------------------------- 1 [R] COG1827 Predicted small molecule binding protein (contains 3H domain) ||||||||||||----||||-|----||||-|--||||--------------------|-||||-- 1 [F] COG1828 Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component ---|||||--|||---||---|---------|||-|||----|||||--------|--|||-|--- 1 [R] COG1832 Predicted CoA-binding protein --|----------------|||----||||-||||||------||-|--||-||||---|||||-| 1 [I] COG1835 Predicted acyltransferases ----------------||||||||||-|||||||-|||------------------|||------- 1 [R] COG1837 Predicted RNA-binding protein (contains KH domain) ||||||||||||||||||--||--||||||||||||||----||||||||||||||----|||||| 1 [J] COG1841 Ribosomal protein L30/L7E --|-------------|-||-|----|||-|----|||----|||||-||------------||-- 1 [KT] COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription ----------------||------||----|----|||----||||||||-----|||||||||-- 1 [N] COG1843 Flagellar hook capping protein ---|------||||--|-||-|----||||----||||----||||||-|--|--|---||||||| 1 [C] COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3 -----------------|||||--||-|||||||-|||---------------------------- 1 [R] COG1847 Predicted RNA-binding protein ---------------------|---|----||||||||----|||||-|-||-||-|||------- 1 [T] COG1854 LuxS protein involved in autoinducer AI2 synthesis ----------------||--|-||-|||||||||||||----|||||||||||||||||||||||| 1 [U] COG1862 Preprotein translocase subunit YajC ||||--||---------|---|----|-------||||----------||---------|||--|| 1 [P] COG1863 Multisubunit Na+/H+ antiporter, MnhE subunit ----------------||------||----|----|||----||||||||-----||||||||--- 1 [N] COG1868 Flagellar motor switch protein ------------------||----||----||||-|||-------|--|-|||------------- 1 [M] COG1876 D-alanyl-D-alanine carboxypeptidase ---|--|||-|-|||-|--|------|||-|||-||||----|||||-||-----|------||-- 1 [H] COG1893 Ketopantoate reductase ---|--|||||||||------|------------||------|||||-||-|----||||||||-- 1 [R] COG1896 Predicted hydrolases of HD superfamily |||-||--||||------|||---------|----|----------|--|-----|---|-|---- 1 [H] COG1903 Cobalamin biosynthesis protein CbiD -|||--|||||||---||-|-------------|||-------||-----------||-------- 1 [S] COG1912 Uncharacterized conserved protein ----||-----|-||----|||----||||||-|||||----|||||--|||||||---||||--- 1 [P] COG1914 Mn2+ and Fe2+ transporters of the NRAMP family ||||||||--||----|||||-----||--|||--|||-------||--|-----||||||||--- 1 [S] COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain |||----|||-------||--|--------||--||------|||||-||--|--|-||----|-- 1 [P] COG1918 Fe2+ transport system protein A -----------------|||-|--|-----|---|||-----|||||-|---|------|-|||-- 1 [M] COG1922 Teichoic acid biosynthesis proteins -|--------------||------------|---||||----|||||-||||||||----||||-- 1 [R] COG1923 Uncharacterized host factor I protein |||-----||------||--|---------||---|------|||--------------------- 1 [I] COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) --------------------|||||||---||||||||||||||||||||||||||---|||||-- 1 [G] COG1925 Phosphotransferase system, HPr-related proteins ------------------|-------|||-||||||||----|||||-||||-||----------- 1 [G] COG1929 Glycerate kinase ||||----|----------|---------------|----------|------------------- 1 [P] COG1930 ABC-type cobalt transport system, periplasmic component --|----------||----|------||||-|---|||----||||||||||||||--||||||-- 1 [HE] COG1932 Phosphoserine aminotransferase -----------------||||---------||||||||---------------------------- 1 [S] COG1939 Uncharacterized protein conserved in bacteria |-------|----------|------|----|||||||----||||------|||||||||-||-- 1 [R] COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog ----------------|||||||-|-|||||---|||||---||||||||||||||||||||||-- 1 [I] COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase ------------------||-|----||||-----|||-----------------|---------- 1 [S] COG1950 Predicted membrane protein -----------------|--|---------|---||||----|||--------------------- 1 [K] COG1954 Glycerol-3-phosphate responsive antiterminator (mRNA-binding) ---|||-------|---|------------||||||||----|||||-||-||||-------||-- 1 [T] COG1956 GAF domain-containing protein -----------------|||-|--||-----|---|||---------------------------- 1 [S] COG1963 Uncharacterized protein conserved in bacteria --|---------------|-||----||||-||||||-----|||||-|||||--|---|||||-- 1 [M] COG1970 Large-conductance mechanosensitive channel -----------------|||-|----||||||--||||----|||||-|||||--|---|||||-- 1 [KT] COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases) --||||-||-||----|-||-|-----||-----||||----|||||-||||---|||||||||-- 1 [H] COG1977 Molybdopterin converting factor, small subunit -----------------|-||---------|----|||----|||||-|--|-------------- 1 [C] COG1979 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family ------------------|||------||||--|||||----|||||-||||---|----|----- 1 [E] COG1982 Arginine/lysine/ornithine decarboxylases ----------------||------||----|----|||----||||||||-----|||||||||-- 1 [NU] COG1987 Flagellar biosynthesis pathway, component FliQ |||---||||--|-----------------|---||||----|||||--|-|-------------- 1 [R] COG1988 Predicted membrane-bound metal-dependent hydrolases ||||--||||------||||-|----|||-||||||||----|||||-||||||||--|---||-- 1 [NOU] COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases ||||||-||||||---||||-|-----||-|----|||----------|----|||||--|-||-- 1 [R] COG1994 Zn-dependent proteases ---------------------|--|-|||||---|||||||||||||--|||||||----|--||| 1 [S] COG2001 Uncharacterized protein conserved in bacteria ---|--|||-|||-----||-------||-|----|||----|||--------------||-|--- 1 [K] COG2002 Regulators of stationary/sporulation gene expression --|-------------|||||---------||||||||----|||||-||||||||---||||--| 1 [L] COG2003 DNA repair proteins ---|---------||--|-|||--------|---||-|----|||||-||-----|---|||||-- 1 [E] COG2008 Threonine aldolase |-||---------||------|----||||----||-------------|||||||------||-- 1 [E] COG2021 Homoserine acetyltransferase ------------------||||----|||-||||||||-----------|||---|---------- 1 [F] COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase --------------|-----|------|||||||-|------|||----|--------|||||||| 1 [R] COG2071 Predicted glutamine amidotransferases ||-|||--||||------|||---------|----|----------|--|-----|---||||--- 1 [H] COG2073 Cobalamin biosynthesis protein CbiG ----------------|---------|||-||-|||||-|--|||||-||||---||||------- 1 [O] COG2077 Peroxiredoxin ------------------||----------||||||||----|||||-||||---|---|||-|-- 1 [R] COG2081 Predicted flavoproteins ||||||--||||------|||------||-|----|----------|--|-----|---||||--- 1 [H] COG2082 Precorrin isomerase |-|-||----|||---|-||-|-----||-||---|||----|||||-||||-|||-|-|||||-- 1 [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases ------------------||||----|||-|----|-|----|||-|-||-----|---||||--- 1 [H] COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase ------------|--|-----|-|-|-||||---|||------------|---------||-|-|| 1 [L] COG2094 3-methyladenine DNA glycosylase ||----------------|||------||-|----|----------|--|-----|---||||--- 1 [H] COG2099 Precorrin-6x reductase --|-||||||||||--||--||-----||---|-||------|||-|--|-----|------|--- 1 [R] COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 --|-||||||---||--|--||--|-----||||||||-|--------|----------------- 1 [F] COG2131 Deoxycytidylate deaminase -----------------|--||--|-||||||||||||----|||||-||||-|||---|------ 1 [R] COG2137 Uncharacterized protein conserved in bacteria --|---|||----||-----------|---||-|||||----|||-|---||----||-|------ 1 [H] COG2145 Hydroxyethylthiazole kinase, sugar kinase family |||-||||-||||----|---|----||||-|||||||----|---------|--|---|||||-- 1 [R] COG2151 Predicted metal-sulfur cluster biosynthetic enzyme --|---||----|---||-----------------|---------|-------------------- 1 [G] COG2152 Predicted glycosylase ---|--||-|-||-----|-------|||-|---||-----------------------||-||-- 1 [R] COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold ---------|-------|--------||||||-|||||----|||||||||||||||||||||||| 1 [E] COG2171 Tetrahydrodipicolinate N-succinyltransferase -----------------|--|---------||||||||||||------------------------ 1 [L] COG2176 DNA polymerase III, alpha subunit (gram-positive type) -------------------|||----||||||||-|||----|||||-|||||||----|||||-- 1 [D] COG2177 Cell division protein -----------------|||-|---------|||||||---------------------------- 1 [R] COG2179 Predicted hydrolase of the HAD superfamily ----|-||--|||----|---|---------|||||||----|||||-|----------|------ 1 [G] COG2182 Maltose-binding periplasmic proteins/domains -------------|||---||---|-|---|||||||||---|||||-||||||||---||||--- 1 [K] COG2183 Transcriptional accessory protein ---------------------|----|||||----|||----|||||-||||-|||---|||||-- 1 [K] COG2186 Transcriptional regulators -----|--|-----------|-----|------|-|--||------|---|||-|-||-|--|--- 1 [L] COG2189 Adenine specific DNA methylase Mod -----------------||||-|||--||-|---||||----------||----------|-|--- 1 [TK] COG2208 Serine phosphatase RsbU, regulator of sigma subunit |-||--||---------|---|----|-------||||----------||---------|||--|- 1 [P] COG2212 Multisubunit Na+/H+ antiporter, MnhF subunit ------------------------------|--|||||-||-|||||||--|-------------- 1 [G] COG2213 Phosphotransferase system, mannitol-specific IIBC component ||||||||||||||---|||||----|||-|-||||||----|||||-||-||--|--|||||--| 1 [R] COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold |-----||-|-------|--||--------|-||-||-----|||||--|--|------|||||-- 1 [M] COG2222 Predicted phosphosugar isomerases --|-||----||-||-||||||||--||||----||||----|||||-||-||||||||||||||| 1 [H] COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis |||-||-----|----||----------------||--------------------|||------- 1 [L] COG2231 Uncharacterized protein related to Endonuclease III ---|||-----|-------------|-||--|||||----|-----|-||----------|-|--- 1 [E] COG2235 Arginine deiminase ||||||--||||------|||-----|||-|----|----------|--|-----|---||||--- 1 [H] COG2241 Precorrin-6B methylase 1 ||||||--||||------|||-----|||-|----|----------|--|---------||||--- 1 [H] COG2242 Precorrin-6B methylase 2 ||||||--||||------|||------||-|----|----------|--|-----|---||||--- 1 [H] COG2243 Precorrin-2 methylase ---||||||||||-----||------||||||-||||-----|---|--|-----|------||-- 1 [S] COG2246 Predicted membrane protein -----------------||||||||||||||||||||||||||||||-|||||||||||||||||| 1 [L] COG2255 Holliday junction resolvasome, helicase subunit -------------||--|--||----|||||||||||||---|||||-||||||||||||||||-- 1 [L] COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase ---------------------|----|||-|---||||----|||-|--||----|--||-|---- 1 [S] COG2258 Uncharacterized protein conserved in bacteria ----------------||||||--------||||||||----|||||-||||||||||||||||-- 1 [J] COG2264 Ribosomal protein L11 methylase -------||----||--|-|||----||||||--||||----|||||-||||---|---|||||-- 1 [I] COG2267 Lysophospholipase -------------||-|---------|||||----|||---------------------|||||-- 1 [R] COG2270 Permeases of the major facilitator superfamily ------------------||||---------|||||||---------------------------- 1 [S] COG2302 Uncharacterized conserved protein, contains S4-like domain --------------|--|---|------------||------|||--------------||-|--- 1 [Q] COG2313 Uncharacterized enzyme involved in pigment biosynthesis ---|--||--|||-------||-------------|||-------|--|-------------|--| 1 [E] COG2317 Zn-dependent carboxypeptidase ---|------------|----|------------||||---------------------------- 1 [S] COG2322 Predicted membrane protein -------------------|-|-----||-|---||||----|||-------|||----|||---| 1 [T] COG2337 Growth inhibitor ---|--||-----------|-|----|-----||||||---------------------------- 1 [S] COG2339 Predicted membrane protein --------|----|-|---|||---||---|---||||-----------|---------|||||-- 1 [S] COG2340 Uncharacterized protein with SCP/PR1 domains -----------------|---|--------||||||||---------------------------- 1 [R] COG2344 AT-rich DNA-binding protein ----||---------------|----|||-----||------|||||-||--|||||||||-||-- 1 [S] COG2353 Uncharacterized conserved protein ------||--|||-|------|||-----------|-|-----------|-----|---|||||-- 1 [E] COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog ------||----|--------|-------------||------------------|------|--- 1 [E] COG2362 D-aminopeptidase --------------|----|-|------------||||----|||||-||||-------|||||-- 1 [S] COG2363 Uncharacterized small membrane protein ------------------||||-----||||||||||----------------------||----- 1 [V] COG2367 Beta-lactamase class A -|-------------------|-------------|--------|-----|-|||----------- 1 [S] COG2369 Uncharacterized protein, homolog of phage Mu protein gp30 ---------------------|----|--------|||----|||||--------|----|-|--- 1 [R] COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC ---------------------|----|---|---||||----|||-|--|---------------- 1 [P] COG2382 Enterochelin esterase and related enzymes ---------------------|--------|||||||||-||------|----------------- 1 [R] COG2384 Predicted SAM-dependent methyltransferase --------|---|-------||----|----|--||------|||---||-|-------|||||-- 1 [R] COG2388 Predicted acetyltransferase ------||---||-|--|-|---------------|-|----------------------|--|-- 1 [C] COG2421 Predicted acetamidase/formamidase ----||--|-|||---------------------|||----------------------------- 1 [S] COG2427 Uncharacterized conserved protein -------------------|||----|---||||||||||--|||||-|----|||---------- 1 [S] COG2501 Uncharacterized conserved protein ----||----|||------|------|||------|||----|||-|-||--||||----|-||-- 1 [G] COG2513 PEP phosphonomutase and related enzymes ----------|-|--------|----|-----||||||---------------------||||--- 1 [R] COG2514 Predicted ring-cleavage extradiol dioxygenase ----------|-|------||-----||-|-||||||-----|||||-||||-|||---|||||-- 1 [S] COG2606 Uncharacterized conserved protein --||||--|--||||-||||||----|---|||-|||||-------|--|||-|||||-|||---- 1 [P] COG2608 Copper chaperone --------------|---------------||-||||-----||||||-|-----|---------- 1 [G] COG2706 3-carboxymuconate cyclase ------------------------------|----|||----|||||---||-||----------- 1 [S] COG2707 Predicted membrane protein -----------------|---|--------|---||||---------------------------- 1 [R] COG2738 Predicted Zn-dependent protease --------------------|---------|||||||||||------------------------- 1 [S] COG2739 Uncharacterized protein conserved in bacteria -------------------|||----||||||||||||||----------------||||||||-- 1 [K] COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination -------------------|-|--------|----||---------------------|-|-|--- 1 [V] COG2746 Aminoglycoside N3'-acetyltransferase ----||-------||--|--|---------||||||--|---------|----||-----|-|--- 1 [F] COG2759 Formyltetrahydrofolate synthetase ---|-------|---------|----|---|---||||----------|---|--|---|||||-- 1 [Q] COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis ---------||-------||-|----||||||--||||----|||||-||-----|---|||||-- 1 [K] COG2771 DNA-binding HTH domain-containing proteins ----------------||||||||------||||||||----|||||-||||||||--|---||-- 1 [NU] COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB ---------------------|----|---|--|-||-----|||-|--|-----|--|--|---- 1 [P] COG2807 Cyanate permease ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [L] COG2812 DNA polymerase III, gamma/tau subunits -|----||-|-|-----|---|---------|||||||----||||||||||-------|||||-- 1 [J] COG2813 16S RNA G1207 methylase RsmC --------------------------|||--|--||||----|||||--||||--||||||-|--- 1 [G] COG2814 Arabinose efflux permease -----------------|--||--||||||||||||||---------------------------- 1 [S] COG2815 Uncharacterized protein conserved in bacteria --------------------------||||-|||||-|----|||||-||||-|||---|||||-- 1 [L] COG2818 3-methyladenine DNA glycosylase ----------------------------------|||-----||||-------||----------- 1 [P] COG2822 Predicted periplasmic lipoprotein involved in iron transport --------------------------|----|||-|------|||||-||||-|||||||||||-- 1 [P] COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism ---|----------------|----------|||||||----|||||-||---||-----||||-- 1 [L] COG2827 Predicted endonuclease containing a URI domain -------------------|-|----|||-----|||-----|||||-||-|-|||------|--- 1 [P] COG2837 Predicted iron-dependent peroxidase -------------------|-|------------||--------|-----|--||----------- 1 [R] COG2842 Uncharacterized ATPase, putative transposase --|------------------|-----||---||-||----------------||-----|-||-- 1 [M] COG2843 Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) -||------||||-------------|---||-|-|-----------------||----------- 1 [S] COG2848 Uncharacterized conserved protein -------------------|-|-------------|------|-------|--||-----|--|-- 1 [S] COG2852 Uncharacterized protein conserved in bacteria --------|-----------|-----|----|||||------|||||--|||-|||--||||||-- 1 [S] COG2855 Predicted membrane protein --------------------|---||----|||||||||-||------------------------ 1 [J] COG2868 Predicted ribosomal protein --||---------||--|---|----|||-||---|-|-----------|-|---|--|||||--- 1 [E] COG2873 O-acetylhomoserine sulfhydrylase ||||||--||||------|||------||-|----|----------|--|-----|---||||--- 1 [H] COG2875 Precorrin-4 methylase ----||-|--|||----|||||||------|-|-||||---------------|------------ 1 [E] COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase -------------------|-|----||||||||-|||----|||||-|||||||----|||||-- 1 [D] COG2884 Predicted ATPase involved in cell division |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG2890 Methylase of polypeptide chain release factors -------------------|----|------|-|||||----|||||-|||||--|---------- 1 [M] COG2891 Cell shape-determining protein ----------------||||||--------|----|||----||||||||--||||||-||||--- 1 [D] COG2894 Septum formation inhibitor-activating ATPase |||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||-- 1 [H] COG2896 Molybdenum cofactor biosynthesis enzyme --|-----------------------||||-|--|||------------|--|--|---|||||-- 1 [S] COG2898 Uncharacterized conserved protein -------------------------------|-|-||-----------||-----|--|||-|--- 1 [R] COG2910 Putative NADH-flavin reductase ------------------------------|----|------||||||||-|-------------- 1 [H] COG2918 Gamma-glutamylcysteine synthetase ------------------------||||||-|||||||----||||||||||||||---||||||| 1 [D] COG2919 Septum formation initiator ------------------|--------||--|--||----------------|-------|-||-- 1 [R] COG2936 Predicted acyl esterases --------------------------|-------||||----|||||-||||---|---|||||-- 1 [R] COG2962 Predicted permeases |------------||-----|-----|||-|--|||-|----|||||-|-|||-----|------- 1 [S] COG2966 Uncharacterized conserved protein --------------------|---------||||||||----------||---------------- 1 [S] COG2996 Uncharacterized protein conserved in bacteria --------------------|----||----|||||---|--|||||-|-||---------|---- 1 [G] COG3010 Putative N-acetylmannosamine-6-phosphate epimerase -----------------------|------|---||||----|||||-|||||||----||||||| 1 [S] COG3027 Uncharacterized protein conserved in bacteria --||----------------------||-------|||----|||||-||-|-||----||||--- 1 [R] COG3030 Protein affecting phage T7 exclusion by the F plasmid --------------------------|-----||||-|-||-|||||-|--|-------------- 1 [S] COG3037 Uncharacterized protein conserved in bacteria ------------------------------|--|||------|||||-||||-|-|----|-||-| 1 [K] COG3070 Regulator of competence-specific genes -------------------------------|||||||----|||||-||||-------------- 1 [S] COG3091 Uncharacterized protein conserved in bacteria -------------|||----------|---||--|||-----|||||-|---|||--------|-- 1 [E] COG3104 Dipeptide/tripeptide permease ----------------------------------||||----||||||-|--|--|---|-|||-- 1 [C] COG3125 Heme/copper-type cytochrome/quinol oxidase, subunit 4 --|----------------|------|----|--||------|||||-||---------|||||-- 1 [R] COG3153 Predicted acetyltransferase --||-----------------|-----||--|---|||-----------|-----|---||-||-| 1 [R] COG3173 Predicted aminoglycoside phosphotransferase --||------------|--||-----|-----|-||-------|||---|-|-|||||-||-|--| 1 [S] COG3177 Uncharacterized conserved protein --------------------|--------------||-----|||-|--|---------------- 1 [E] COG3192 Ethanolamine utilization protein ----------||------|----------------|------|---|--|-----|---|-|||-- 1 [R] COG3193 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol --|---------------------------|----||-----|||||--|-----|------|--- 1 [M] COG3209 Rhs family protein --|-----------------|-----------|-||||----------||---||-------||-- 1 [S] COG3212 Predicted membrane protein -------------------------------|---||-----|||||--||--------------- 1 [S] COG3223 Predicted membrane protein -------------------|------|----||||||-----|||-|--|---------||-||-- 1 [S] COG3237 Uncharacterized protein conserved in bacteria ---|||-----||--------|----||||----||||---------------------------- 1 [S] COG3253 Uncharacterized conserved protein ----||-----------------------------|||----|||||-----------|||||--- 1 [S] COG3254 Uncharacterized conserved protein --------------------|-----||-||---||||-----------|---------------- 1 [S] COG3323 Uncharacterized protein conserved in bacteria ---|---------|---------------------|-|--------|-|----------------- 1 [G] COG3325 Chitinase --|----------------------------|||-|||--------|--|---||-|--|------ 1 [S] COG3326 Predicted membrane protein -------------------------------|||||||||||------------------------ 1 [R] COG3331 Penicillin-binding protein-related factor A, putative recombinase -------------------|---------------|-|----------|--|----||--|-|--- 1 [P] COG3338 Carbonic anhydrase -------------------|||----|--------|||----|||-|---||-------------- 1 [E] COG3340 Peptidase E -------------------------------||||||||-||------------------------ 1 [K] COG3343 DNA-directed RNA polymerase, delta subunit ---|-------|-------|------|||--||--|-------|||------|--|---------- 1 [R] COG3378 Predicted ATPase |---||-----|----------------------|||----------------------||-|--- 1 [R] COG3383 Uncharacterized anaerobic dehydrogenase --|----------------|----|--||------|-|-------------------------|-- 1 [R] COG3393 Predicted acetyltransferase -------------------------------|---|-|-------|--||---------------- 1 [S] COG3397 Uncharacterized protein conserved in bacteria ---|----------------------||------||||---------------------------- 1 [S] COG3402 Uncharacterized conserved protein ---|||-----|-|||---------|-----|||||------------------------------ 1 [I] COG3407 Mevalonate pyrophosphate decarboxylase ||||||||||||||||---------|-----||||||--------|-----------------|-- 1 [I] COG3425 3-hydroxy-3-methylglutaryl CoA synthase -----------------|---|--------|----||----------------------------- 1 [C] COG3426 Butyrate kinase ---|----------------------|||-----||||---------------------------- 1 [S] COG3428 Predicted membrane protein ------------------------------|----|||----|||-|--------|------||-- 1 [L] COG3449 DNA gyrase inhibitor -----------------|------------|----|---------|--|----------||||--- 1 [G] COG3459 Cellobiose phosphorylase -------------------------------|---|------------||---------------- 1 [G] COG3469 Chitinase --------------------------||||-|||-|||---------------------------- 1 [T] COG3480 Predicted secreted protein containing a PDZ domain -|-------|----------|---------||||||||----------------------|----- 1 [R] COG3481 Predicted HD-superfamily hydrolase --------------------------------|--|---------------|--|---|------- 1 [S] COG3513 Uncharacterized protein conserved in bacteria --|---------------------------||-||||-----------|----------------- 1 [Q] COG3527 Alpha-acetolactate decarboxylase ------|----|-----------------------|-|---------------------|--|--- 1 [S] COG3535 Uncharacterized conserved protein -------------------------------|||||||||-------------------------- 1 [J] COG3557 Uncharacterized domain/protein associated with RNAses G and E -------------|----------------||--||-------------|---||----|-|---- 1 [R] COG3560 Predicted oxidoreductase related to nitroreductase -----------------------------------|--------------|-|---------|--- 1 [S] COG3566 Uncharacterized protein conserved in bacteria -----------------------------------|--------------|-|---------|--- 1 [S] COG3567 Uncharacterized protein conserved in bacteria --------------------------------||-|------|||-|--|--|--|---|||||-- 1 [R] COG3568 Metal-dependent hydrolase -------------|----------|------|||-|------------------------------ 1 [E] COG3579 Aminopeptidase C ----------------||--|---------||---|------------------------------ 1 [S] COG3580 Uncharacterized protein conserved in bacteria ----------------||--|---------||---|------------------------------ 1 [S] COG3581 Uncharacterized protein conserved in bacteria --------------------------|||||----|||---------------------------- 1 [S] COG3583 Uncharacterized protein conserved in bacteria -----------|-------------|-----||-||-|---------------------------- 1 [S] COG3589 Uncharacterized conserved protein --|----------------------------|---|------|||-----------------|--- 1 [S] COG3592 Uncharacterized conserved protein --|---------------------------|---|||------------|--|---------|--- 1 [G] COG3594 Fucose 4-O-acetylase and related acetyltransferases ------||---------|------------|||||||----------------------------- 1 [S] COG3601 Predicted membrane protein --------------------------|----|--||-|---------------------||-|--- 1 [R] COG3607 Predicted lactoylglutathione lyase |------------||-----|-----|||-|--|||-|----|||||-|-|||-----|------- 1 [S] COG3610 Uncharacterized conserved protein -------------------------------||||||||-||------------------------ 1 [L] COG3611 Replication initiation/membrane attachment protein --|---------------|-|------||-||||-||------------|-----|---||||--- 1 [S] COG3619 Predicted membrane protein --------------------|---|-------|-||-|---------------------------- 1 [R] COG3641 Predicted membrane protein, putative toxin regulator -------------------|------|---|-||-|||-----------|-------------|-- 1 [K] COG3655 Predicted transcriptional regulator ----------------------------------||-|-----------|----------|--|-- 1 [G] COG3664 Beta-xylosidase --------------------------------||||------|||-|---------------|--- 1 [G] COG3684 Tagatose-1,6-bisphosphate aldolase ------------------||----------|-|-||||---------------------------- 1 [R] COG3688 Predicted RNA-binding protein containing a PIN domain ------------------||----------|-||-|||---------------------------- 1 [S] COG3689 Predicted membrane protein --------------|------|----|||--|---|------|||||-||---------------- 1 [L] COG3695 Predicted methylated DNA-protein cysteine methyltransferase ----------------|-||-|--------||---|||-----------|---|||---|||||-- 1 [E] COG3705 ATP phosphoribosyltransferase involved in histidine biosynthesis --------------------|------||||----|-------------|-----|---||-||-- 1 [T] COG3707 Response regulator with putative antiterminator output domain --------------------------|--------|||-------||--------|---|||||-- 1 [G] COG3718 Uncharacterized enzyme involved in inositol metabolism -------------------------------||-|||------|||---|------------|--- 1 [L] COG3728 Phage terminase, small subunit -----------------------------------|-|----|||-|----|----------|--- 1 [G] COG3730 Phosphotransferase system sorbitol-specific component IIC -----------------------------------|-|----|||-|----|----------|--- 1 [G] COG3731 Phosphotransferase system sorbitol-specific component IIA -----------------------------------|-|----||--|----|----------|--- 1 [G] COG3732 Phosphotransferase system sorbitol-specific component IIBC -------------------------------|---|||-------------|-------|---|-- 1 [S] COG3739 Uncharacterized integral membrane protein ---------------------------||--|---|-------||-|--------|---|---|-- 1 [R] COG3740 Phage head maturation protease --------------|------------||--|---|-----------------------|--||-- 1 [S] COG3752 Predicted membrane protein --------------------------|----|-|||--------------|--|||---|--|--- 1 [S] COG3759 Predicted membrane protein -------------------------------|||||||||||------------------------ 1 [S] COG3763 Uncharacterized protein conserved in bacteria |--------|----------------|---||||||||---------------------------- 1 [M] COG3764 Sortase (surface protein transpeptidase) ---------------------------||||----|-----------------------|||||-- 1 [S] COG3786 Uncharacterized protein conserved in bacteria ---------------------------||----|-|-----------------------||-||-- 1 [S] COG3797 Uncharacterized protein conserved in bacteria ----------------|-------------|----|||----|||-|--|-----|---------- 1 [KT] COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains -||-----|||---------------||||||-|-|-------------|---||----------- 1 [T] COG3830 ACT domain-containing protein --|--------------|--------|||-|---||||-----------|-----|---||-||-- 1 [S] COG3832 Uncharacterized conserved protein ----|--|--||-----|---|---------|||||||-|--|||||-|----------------- 1 [G] COG3833 ABC-type maltose transport systems, permease component |||||||||||||---||||||--|-||||||||||||-||||||||-||-||--|--|||||--- 1 [G] COG3839 ABC-type sugar transport systems, ATPase components ---|--|||-|-|----|-|-|--||----||||-||-||||-------|-----|---||||--- 1 [R] COG3845 ABC-type uncharacterized transport systems, ATPase components ---|--------------||--------------||||---------------------------- 1 [T] COG3848 Phosphohistidine swiveling domain --|------------------|--------|||-||||---------------------------- 1 [P] COG3853 Uncharacterized protein involved in tellurite resistance --------------------|---------||--|||----------------------------- 1 [G] COG3855 Uncharacterized protein conserved in bacteria ------------------------------||||||||---------------------------- 1 [L] COG3857 ATP-dependent nuclease, subunit B ------------------------------|||--|||---------------------------- 1 [S] COG3859 Predicted membrane protein --------------------------|---||--||-------------|-----|---||-|--- 1 [S] COG3865 Uncharacterized protein conserved in bacteria ----------------------||------|---||||---------------------------- 1 [E] COG3869 Arginine kinase ---------------------|--------|---||||---------------------------- 1 [S] COG3870 Uncharacterized protein conserved in bacteria -------------------|-|--------|---|||----------------------|------ 1 [R] COG3871 Uncharacterized stress protein (general stress protein 26) -----------------|--|---------|----|||---------------------------- 1 [R] COG3872 Predicted metal-dependent enzyme ----------------------||------|---||||---------------------------- 1 [S] COG3880 Uncharacterized protein with conserved CXXC pairs ------------------------------||||||||-|-------------------------- 1 [T] COG3887 Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain -----------------|------------||||||||---------------------------- 1 [S] COG3906 Uncharacterized protein conserved in bacteria |-|---------------|||------||||----|-----------------------|||||-- 1 [T] COG3920 Signal transduction histidine kinase --------------------------|--------|||-------||--------|---|||||-- 1 [E] COG3962 Acetolactate synthase -------------------------------||||||----------------------------- 1 [M] COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) -------------------------------||--|------|||-|--|-----|---------- 1 [R] COG3969 Predicted phosphoadenosine phosphosulfate sulfotransferase -------------------|---------------|-|---------------------|-||--- 1 [E] COG4091 Predicted homoserine dehydrogenase -------------------------------|||||||---------------------------- 1 [L] COG4098 Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) ------------------||----------|---||||---------------------------- 1 [P] COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance ------------------||-|----|---||||||------||||||||||||||---|||||-- 1 [J] COG4108 Peptide chain release factor RF-3 ------------------------------||||||||---------------------------- 1 [K] COG4109 Predicted transcriptional regulator containing CBS domains -------------------------------|||||||---------------------------- 1 [S] COG4116 Uncharacterized protein conserved in bacteria --||--------|-|-|-||||----||||||||||||-----------|---||-------|--- 1 [R] COG4122 Predicted O-methyltransferase ----------------||--|---------||||||||||--|||||-|-||----||||||||-- 1 [R] COG4123 Predicted O-methyltransferase --|---------|---|-||------|||-----||||----|||||-||||---|||||||||-- 1 [P] COG4149 ABC-type molybdate transport system, permease component -||----------------------------|-|||||-------------------------|-- 1 [R] COG4152 ABC-type uncharacterized transport system, ATPase component --|----------------------|-----||--||-----|||||--|-----|---||||--- 1 [E] COG4175 ABC-type proline/glycine betaine transport system, ATPase component --|----------------------|-----||--||-----|||||--|-----|---||||--- 1 [E] COG4176 ABC-type proline/glycine betaine transport system, permease component ----|------|--------------|---|----|------------------------------ 1 [R] COG4194 Predicted membrane protein ----||-----------|------------|----|------------------------------ 1 [S] COG4198 Uncharacterized conserved protein -------------------------------|||||||---------------------------- 1 [S] COG4199 Uncharacterized protein conserved in bacteria -------------------------------|||-|||---------------------|------ 1 [G] COG4209 ABC-type polysaccharide transport system, permease component ---|---------||---||||----|||--|-|||------|||-|-||||||||||||||---- 1 [R] COG4221 Short-chain alcohol dehydrogenase of unknown specificity ----||-----|-------------------|---|------------------------------ 1 [S] COG4272 Predicted membrane protein -------------|------|----------|-|-|---------------|-------------- 1 [S] COG4283 Uncharacterized conserved protein ---------------------|------------||-------------------|---||----- 1 [S] COG4292 Predicted membrane protein --------------------|---------|----|------|||-|--|-----|---------- 1 [E] COG4302 Ethanolamine ammonia-lyase, small subunit --------------------|---------|----|------|||-|--|-----|---------- 1 [E] COG4303 Ethanolamine ammonia-lyase, large subunit ------------------||----|---------||------------------------------ 1 [S] COG4330 Predicted membrane protein ---|------------------------------||||---------------------------- 1 [S] COG4347 Predicted membrane protein ---------------------|---------|--||------------------------------ 1 [S] COG4367 Uncharacterized protein conserved in bacteria ---------------------|---------|-|||-|----------||-----|---------- 1 [S] COG4392 Predicted membrane protein ------------------|||-------------||||---------------------------- 1 [S] COG4399 Uncharacterized protein conserved in bacteria ------------------||---------------|||---------------------------- 1 [E] COG4401 Chorismate mutase ------------------------------||-|-|||-----|-||------------------- 1 [S] COG4405 Uncharacterized protein conserved in bacteria -------------------|--------------||||----------------------|-||-- 1 [S] COG4430 Uncharacterized protein conserved in bacteria ------------------------|-----||||-|------------------------------ 1 [S] COG4443 Uncharacterized protein conserved in bacteria ------------------------------||||||||---------------------------- 1 [K] COG4463 Transcriptional repressor of class III stress genes ------------------------------||||||||---------------------------- 1 [K] COG4465 Pleiotropic transcriptional repressor ------------------------------||||||||---------------------------- 1 [S] COG4466 Uncharacterized protein conserved in bacteria -------------------------------|||||||---------------------------- 1 [S] COG4467 Uncharacterized protein conserved in bacteria -------------------------------|||||||---------------------------- 1 [R] COG4469 Competence protein -------------------------------|||||||---------------------------- 1 [S] COG4470 Uncharacterized protein conserved in bacteria -------------------------------|||||||---------------------------- 1 [S] COG4471 Uncharacterized protein conserved in bacteria ------------------------------||||||-|---------------------------- 1 [S] COG4472 Uncharacterized protein conserved in bacteria -------------------------------|||||||---------------------------- 1 [U] COG4473 Predicted ABC-type exoprotein transport system, permease component -------------------------------|||||||---------------------------- 1 [S] COG4474 Uncharacterized protein conserved in bacteria -------------------------------|||||||---------------------------- 1 [S] COG4476 Uncharacterized protein conserved in bacteria -------------------------------|||||||---------------------------- 1 [D] COG4477 Negative regulator of septation ring formation -------------------------------||||||----------------------------- 1 [S] COG4479 Uncharacterized protein conserved in bacteria ------------------------------|-||||-|---------------------------- 1 [S] COG4481 Uncharacterized protein conserved in bacteria -------------------------------||||||----------------------------- 1 [S] COG4483 Uncharacterized protein conserved in bacteria -------------------------------|--||||---------------------------- 1 [S] COG4493 Uncharacterized protein conserved in bacteria ------------------------------|---||||--------------|------------- 1 [S] COG4496 Uncharacterized protein conserved in bacteria ------------------------------|---||||---------------------------- 1 [S] COG4499 Predicted membrane protein ------------------------------|---||||---------------------------- 1 [S] COG4506 Uncharacterized protein conserved in bacteria --------------------------------|-||-|---------------------------- 1 [S] COG4509 Uncharacterized protein conserved in bacteria ------------------------------|---||-|---------------------------- 1 [OTK] COG4512 Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide ---------------------|-------------|||----|||||-|----------------- 1 [R] COG4533 ABC-type uncharacterized transport system, periplasmic component -------------------------------|||||||---------------------------- 1 [U] COG4537 Competence protein ComGC ------------------------------|----|----------|---------------|--- 1 [Q] COG4542 Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase -----------------------------------||----------------------||||--- 1 [S] COG4549 Uncharacterized protein conserved in bacteria -------------------------------||-||||---------------------------- 1 [S] COG4550 Predicted membrane protein --|------------------------||-----||-|-----|||---------|---||-|--- 1 [L] COG4584 Transposase and inactivated derivatives ------------------||-|----|||-||||||||-----------|-----|---||-||-- 1 [T] COG4585 Signal transduction histidine kinase ---|--|||-|-|----|-|-|--||----||||-||-||||-------|-----|---||||--- 1 [R] COG4603 ABC-type uncharacterized transport system, permease component --|||||||-|||---||--||||-||---||||||||-||||||||-||||---||||||||--- 1 [E] COG4608 ABC-type oligopeptide transport system, ATPase component ------------------------------||--||------|||-----------------|--- 1 [R] COG4626 Phage terminase-like protein, large subunit --|--------------|--|---||---------|------||||||||||-------------- 1 [C] COG4656 Predicted NADH:ubiquinone oxidoreductase, subunit RnfC ---------------------|--------||-|||||--|-||||||||||---|---------- 1 [G] COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain ---||-----|-|-------|-------------||-|----|||-|--------|----|||--- 1 [I] COG4670 Acyl CoA:acetate/3-ketoacid CoA transferase ------------------------------||||-|------------------------------ 1 [S] COG4687 Uncharacterized protein conserved in bacteria -------------------------------||--|||---------------------------- 1 [S] COG4698 Uncharacterized protein conserved in bacteria -------------------------------|||||------------------------------ 1 [S] COG4699 Uncharacterized protein conserved in bacteria -------------------------------|||-||----------------------------- 1 [S] COG4703 Uncharacterized protein conserved in bacteria ------------------------------||||-|------------------------------ 1 [S] COG4708 Predicted membrane protein ------------------------------|-||||---------------------------|-- 1 [S] COG4709 Predicted membrane protein -------------------------------||-||------------------------------ 1 [S] COG4716 Myosin-crossreactive antigen --|-------------------------------|||-----------------------|----- 1 [S] COG4717 Uncharacterized conserved protein ------------------------------|||--|||---------------------------- 1 [S] COG4722 Phage-related protein --|----------------|-----||--------|------------------------------ 1 [S] COG4748 Uncharacterized conserved protein --------------------|-----------||||||---------------------------- 1 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain -------------------------------|||||||---------------------------- 1 [S] COG4758 Predicted membrane protein --------------------|--------------|------|||-|------------|------ 1 [E] COG4766 Ethanolamine utilization protein -------------------------------|||||||---------------------------- 1 [R] COG4768 Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain -----------------|--|---|------|---|------------------------------ 1 [S] COG4769 Predicted membrane protein -------------------------------|||||------------------------------ 1 [C] COG4781 Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase ----------------||------||----|----|||----||||||||-----|||||||||-- 1 [N] COG4786 Flagellar basal body rod protein -----------------------------------|||----|||||------------------- 1 [G] COG4806 L-rhamnose isomerase ----------------------------------||------|||-|------------------- 1 [S] COG4808 Uncharacterized protein conserved in bacteria --------------------|--------------|------|||-|------------------- 1 [E] COG4810 Ethanolamine utilization protein -----------------------------------|------|||||----|-------------- 1 [S] COG4811 Predicted membrane protein --------------------|--------------|------|||-|------------------- 1 [E] COG4812 Ethanolamine utilization cobalamin adenosyltransferase -----------------------------------|-|---------------------||||--- 1 [G] COG4813 Trehalose utilization protein --------------------------|-------||------------------------------ 1 [S] COG4815 Uncharacterized protein conserved in bacteria -------------------------------|---|-|---------------------------- 1 [S] COG4817 Uncharacterized protein conserved in bacteria --------------------|--------------|------|||-|------------------- 1 [E] COG4819 Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition --------------------|--------------|------|||-|------------------- 1 [E] COG4820 Ethanolamine utilization protein, possible chaperonin --------------------|---------|----|----------|------------------- 1 [H] COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase ------------------------------|----|||---------------------------- 1 [R] COG4824 Phage-related holin (Lysis protein) --|-----------------|----------|---|------------------------------ 1 [S] COG4832 Uncharacterized conserved protein --------------------------|||------|------------------------------ 1 [G] COG4833 Predicted glycosyl hydrolase -----------------------------------|----------------|---------|--- 1 [S] COG4834 Uncharacterized protein conserved in bacteria -------------------------------|||-|------------------------------ 1 [S] COG4835 Uncharacterized protein conserved in bacteria ----------------------------------||||---------------------------- 1 [S] COG4836 Predicted membrane protein ----------------------------------||||---------------------------- 1 [S] COG4837 Uncharacterized protein conserved in bacteria ----------------------------------||||---------------------------- 1 [S] COG4838 Uncharacterized protein conserved in bacteria -------------------------------|||||||---------------------------- 1 [D] COG4839 Protein required for the initiation of cell division ----------------------------------||||---------------------------- 1 [S] COG4840 Uncharacterized protein conserved in bacteria ----------------------------------||||---------------------------- 1 [S] COG4841 Uncharacterized protein conserved in bacteria --------------------------|||||---||||---------------------------- 1 [S] COG4842 Uncharacterized protein conserved in bacteria ----------------------------------||||---------------------------- 1 [S] COG4843 Uncharacterized protein conserved in bacteria ----------------------------------||||---------------------------- 1 [S] COG4844 Uncharacterized protein conserved in bacteria ----------------------------------||||---------------------------- 1 [O] COG4846 Membrane protein involved in cytochrome C biogenesis ----------------------------------||||---------------------------- 1 [S] COG4848 Uncharacterized protein conserved in bacteria ----------------------------------||||---------------------------- 1 [R] COG4851 Protein involved in sex pheromone biosynthesis -------------------------------|---|-----------------------|--|--- 1 [S] COG4852 Predicted membrane protein ----------------------------------||||---------------------------- 1 [S] COG4853 Uncharacterized protein conserved in bacteria ------------------------------|-||||||---------------------------- 1 [S] COG4856 Uncharacterized protein conserved in bacteria -------------------------------|||-|------------------------------ 1 [S] COG4858 Uncharacterized membrane-bound protein conserved in bacteria -------------------------------|||||||---------------------------- 1 [OTN] COG4862 Negative regulator of genetic competence, sporulation and motility ----------------------------------||||---------------------------- 1 [S] COG4863 Uncharacterized protein conserved in bacteria ----------------------------------||||---------------------------- 1 [S] COG4864 Uncharacterized protein conserved in bacteria ----------------------------------|||----------------------------- 1 [S] COG4873 Uncharacterized protein conserved in bacteria ----------------------------------|||----------------------------- 1 [S] COG4876 Uncharacterized protein conserved in bacteria --------------------|--------------|------|----------------------- 1 [S] COG4884 Uncharacterized protein conserved in bacteria --------------------------|||------|--------------------||-------- 1 [R] COG4889 Predicted helicase ----------------------------------|||----------------------------- 1 [S] COG4896 Uncharacterized protein conserved in bacteria ----------------------------------|||----------------------------- 1 [S] COG4897 Uncharacterized protein conserved in bacteria ---------------------------------|-|------------------------|----- 1 [S] COG4898 Uncharacterized protein conserved in bacteria ----------------------------------|||----------------------------- 1 [K] COG4903 Genetic competence transcription factor ------------------------------||---|------------------------------ 1 [S] COG4905 Predicted membrane protein --|------------------------||-|----|------------------------------ 1 [R] COG4908 Uncharacterized protein containing a NRPS condensation (elongation) domain -----------------------------------|----------|---------------|--- 1 [Q] COG4909 Propanediol dehydratase, large subunit -----------------------------------|----------|---------------|--- 1 [Q] COG4910 Propanediol dehydratase, small subunit --|-----------------|-----|----|---|------------------------|-|--| 1 [L] COG4912 Predicted DNA alkylation repair enzyme -------------------------------|--|||----------------------------- 1 [R] COG4915 5-bromo-4-chloroindolyl phosphate hydrolysis protein --------------------|--------------|------|||-|------------------- 1 [E] COG4917 Ethanolamine utilization protein -------------------------------|---||----------------------------- 1 [S] COG4918 Uncharacterized protein conserved in bacteria ------------------------------|||--|------------------------------ 1 [S] COG4926 Phage-related protein ------------------------------|----|----------|------------------- 1 [TK] COG4936 Predicted sensor domain ----------|------------------------|------------|----------------- 1 [S] COG4938 Uncharacterized conserved protein --------------------|---|----------|------------------------------ 1 [S] COG4939 Major membrane immunogen, membrane-anchored lipoprotein -------------------------------|||||||------------------|||------- 1 [U] COG4940 Competence protein ComGF ----------------------------------||||---------------------------- 1 [S] COG4955 Uncharacterized protein conserved in bacteria ------------------||-|--------||--||||---------------------------- 1 [R] COG4956 Integral membrane protein (PIN domain superfamily) --||-------------------------------|--------------------------|--- 1 [S] COG4983 Uncharacterized conserved protein -------------------------------|--||||----|||||-|-||-------|-|-|-- 1 [CO] COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components ------------------------------|--|||||----|||||-|----------|--|--- 1 [R] COG4989 Predicted oxidoreductase |||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||-- 1 [E] COG4992 Ornithine/acetylornithine aminotransferase ------------------------------|----|-------------------|---------- 1 [S] COG4994 Uncharacterized protein conserved in bacteria ---------------------|---------|||||||---------------------------- 1 [T] COG5002 Signal transduction histidine kinase --|------------------|---------|--|||----------------------------- 1 [S] COG5280 Phage-related minor tail protein ------------------------------||---|-------||-|-----|------------- 1 [S] COG5283 Phage-related tail protein -------------------------------|--|||----------------------------- 1 [S] COG5294 Uncharacterized protein conserved in bacteria -----------------------------------||------------------|---------- 1 [S] COG5298 Uncharacterized protein conserved in bacteria -----------------------------------|-----------------------||||--- 1 [R] COG5350 Predicted protein tyrosine phosphatase -------------------------------|-|-|||---------------------------- 1 [S] COG5353 Uncharacterized protein conserved in bacteria --|--------------------------------|--------------------------|--| 1 [R] COG5362 Phage-related terminase ----------------||-------|--------||||----|||||||||||--||||||||||| 1 [O] COG5405 ATP-dependent protease HslVU (ClpYQ), peptidase subunit -----------------------------------|-|--------------|------------| 1 [S] COG5410 Uncharacterized protein conserved in bacteria --------------------------------|-||-|---------------------------- 1 [S] COG5412 Phage-related protein --------------------------||||-----|||---------------|||---------- 1 [S] COG5416 Uncharacterized integral membrane protein ----------------------------------||||---------------------------- 1 [S] COG5417 Uncharacterized small protein -----------------------------------|-|---------------------|-|-|-- 1 [S] COG5437 Predicted secreted protein ----------------------------------||||---------------------------- 1 [S] COG5444 Uncharacterized conserved protein ------------------------------|----||------||||------------------- 1 [N] COG5492 Bacterial surface proteins containing Ig-like domains -------------------------------|||||||---------------------------- 1 [S] COG5503 Uncharacterized conserved small protein --------------------------------||-|||---------------------------- 1 [S] COG5506 Uncharacterized conserved protein -----------------------------------||---------|--------|---------- 1 [R] COG5518 Bacteriophage capsid portal protein --------------------------------||-||----------------------------- 1 [S] COG5521 Predicted integral membrane protein ------------------------------||||-|------------------------------ 1 [S] COG5523 Predicted integral membrane protein ------------------------------|---||-----------------|------------ 1 [L] COG5527 Protein involved in initiation of plasmid replication ---------------------------||--|--||------|||-|------------------- 1 [R] COG5562 Phage envelope protein -------------------------------|||-|||---------------------------- 1 [S] COG5578 Predicted integral membrane protein ----------------------------------||||---------------------------- 1 [S] COG5582 Uncharacterized conserved protein ----------------------------------||||---------------------------- 1 [S] COG5584 Predicted small secreted protein --||-------------|---|--------|----|-|-----------------|---------- 1 [S] COG5652 Predicted integral membrane protein ------------------------------|---||-|---------------------------- 1 [L] COG5655 Plasmid rolling circle replication initiator protein and truncated derivatives |||||||||||||||---||||--------|-|-|-||----|||-|-||-|||||||-||||--- 0 [E] COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family ||-||||||||--|--|||-------|||-|--||-||---------------------------- 0 [S] COG0011 Uncharacterized conserved protein -|----||---|------||------|||-------|-----|||||-||-|-------------- 0 [F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) -|||||||||-||||-|-||||----|||-||||---|----|||||-|-||-|||---|-|||-- 0 [P] COG0038 Chloride channel protein EriC |||-||||||||||--|-||-|||------------||----|||||-||-|-|||||||||-||| 0 [H] COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases ||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||--|||||||| 0 [C] COG0045 Succinyl-CoA synthetase, beta subunit ||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||-- 0 [H] COG0054 Riboflavin synthase beta-chain -||---||--||-|--|-||||||--|||-||||--||----|||||-||||-------||-|--- 0 [G] COG0058 Glucan phosphorylase |||||||||||||||-||||-|-----||||---|-||----||||||||--|--|---||||||| 0 [O] COG0071 Molecular chaperone (small heat shock protein) ||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||--|||||||| 0 [C] COG0074 Succinyl-CoA synthetase, alpha subunit ||||||||||||||--||||-|--------||--|-||--------|-||------||-||-||-- 0 [E] COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase ||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||-- 0 [H] COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase -------------||-||||||||--||||||-||-||----||||||||||||||||||||||-- 0 [H] COG0117 Pyrimidine deaminase |-||--|||---||||--|--|-----||-|-----||-|--|||||-||--|--|---|||||-- 0 [L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase ||||--|||||||||||-||-|------------|-||----------||---|||---|||||-- 0 [BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein -|-----------|--|-|||--|--|||||---|-||----||||||||||||||||||-|||-- 0 [H] COG0132 Dethiobiotin synthetase ------|---|--||--|--|---|-|||-||-|--||----|||||-|-||-------------- 0 [G] COG0153 Galactokinase --------|-||-||-|-||-|----|||-|-----||----||||||||--||||---|||||-- 0 [P] COG0155 Sulfite reductase, beta subunit (hemoprotein) -|--||||-----||||-||||||---|||----|-||----|||||-|||||||||||||||||| 0 [H] COG0156 7-keto-8-aminopelargonate synthetase and related enzymes --||||||--|||||----|-|----|||||---|-||----|||||-|||----|---||||--- 0 [E] COG0160 4-aminobutyrate aminotransferase and related aminotransferases -|-----------||-|---||-|--|||||---|-||----||||||||||||||||||||||-- 0 [H] COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase |||-||||||||||--|-||-|||------------||----|||||-||-|-|||||||||-||| 0 [H] COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase -||||-||-||||||---||||----|||-|-----||----||||||||--||||---|||||-- 0 [EH] COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes |||-|||||||||||-|||||---------------|------------|--|-------|-|--- 0 [J] COG0182 Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family -|||--|||-|||-----||-|---------------|--||||||||||||||||---|||||-- 0 [HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) ------------------||||||--|||||||||-|||||||||||-||||||||--||||||-- 0 [J] COG0219 Predicted rRNA methylase (SpoU class) ||-||||||||||---|-||-|----|||-------||----|||||-||||---|||||||||-- 0 [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing -------------|---|--------|---||-||-||-||-||||||||-|---|---|||||-- 0 [G] COG0246 Mannitol-1-phosphate/altronate dehydrogenases ||||||--|||||---|-||||----||||-|----||----|||||-||||-||||||||||--- 0 [C] COG0247 Fe-S oxidoreductase --|--------|-|--||||||----|||||------|----|||||-|||||||||||||||||| 0 [FP] COG0248 Exopolyphosphatase ------------|-|||-||||||--||||----|-|||||||||||||||||-|||||||||||| 0 [E] COG0260 Leucyl aminopeptidase |||---|||||||-----------------|-|||-|--||-|||-|-|-||-------------- 0 [G] COG0269 3-hexulose-6-phosphate synthase and related proteins ||----||-||||-|---||------|---|-||--||||--|||-|-|-|-||||||--|-||-- 0 [L] COG0270 Site-specific DNA methylase --||||--|-|||||-|-||||----|||||-----||----|||||-||||||||||||||||-- 0 [C] COG0277 FAD/FMN-containing dehydrogenases |--|------||-||---||-|----|||||-||--||----|||||-||||||||||||||||-- 0 [P] COG0288 Carbonic anhydrase --|--------|-|--|-||||||--|||----|--|-----|||||-||||---|---||-|--- 0 [G] COG0296 1,4-alpha-glucan branching enzyme -|----||--||--|-||||||||------||-|--||----|||||-||||---|---||-|--- 0 [G] COG0297 Glycogen synthase ---|---------||-||||||||--||||||-||-||----||||||||||||||||||||||-- 0 [H] COG0307 Riboflavin synthase alpha chain |||-|||||||||---||||-|-----||-|------|----||||||||||||||---|||||-- 0 [R] COG0312 Predicted Zn-dependent proteases and their inactivated homologs --|----------||-|-||-|----||||----|-||----||||||||||||||---||||||| 0 [S] COG0316 Uncharacterized conserved protein ---|------|||||-|-||-|||--||||----|-||----||||||||||||||---||||||| 0 [H] COG0320 Lipoate synthase |||||||||||||||-||||||--||||||||||---|-|--|||||||||||||||||||||||| 0 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs -------------|||--||--||----------|-||----||||||||--|||----|-|-|-- 0 [P] COG0369 Sulfite reductase, alpha subunit (flavoprotein) --||----|----|----|--------||--------|----|||||-|---|--|---||-||-- 0 [P] COG0376 Catalase (peroxidase I) |||-----||----|-|-||||----|||-----|--||---|||||--||----||||||||--- 0 [OK] COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase |||||||||||||||-|-||-|||--|||||------|----|||||-||-||||||||||||||| 0 [H] COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases --|----------|--|-||------|--|----|-||----|||||--|---|||---|||||-- 0 [R] COG0385 Predicted Na+-dependent transporter -------------||---||-|----||||------|-----|||||------------||-|--- 0 [P] COG0387 Ca2+/H+ antiporter -||-------------||||-------||-----|-|-----|||-|--------|---------- 0 [R] COG0390 ABC-type uncharacterized transport system, permease component -------------||---||------|----------|----|||-|-||--|--|---||--|-- 0 [S] COG0397 Uncharacterized conserved protein ||-----|-||-----||||----|-|||-|--|--|-----|||||-||-|-||||||-||||-- 0 [M] COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis |||||||||||||||-||||-|----|---|--|---|----|||||--||||--|||||||||-- 0 [FR] COG0402 Cytosine deaminase and related metal-dependent hydrolases ----||----||||||--||||----|||-----|-||----|||-|-||--||||||-||-||-- 0 [E] COG0405 Gamma-glutamyltransferase -|------|-|||----|||||----|------|---|----|||||--|-----|--|||||--- 0 [E] COG0410 ABC-type branched-chain amino acid transport systems, ATPase component --|-|------|-||-|-||-------|||------|-----|||||--|-----|---||-||-- 0 [Q] COG0412 Dienelactone hydrolase and related enzymes -|--|||||||||||-||---|----|---|--|--||----||||||-|--||||||----|--- 0 [E] COG0421 Spermidine synthase ||||---|||||----||||||----|||||-----||----|||||-||--||||--|||-||-- 0 [H] COG0422 Thiamine biosynthesis protein ThiC ||||||||||||||||-----|--|||||||---|---||||------------------------ 0 [J] COG0423 Glycyl-tRNA synthetase (class II) --|---||-----||-||||||||--|||||-----||----|||||-||-||||||||||||||| 0 [D] COG0424 Nucleotide-binding protein implicated in inhibition of septum formation ||||||--||||----|||||-------------|-|-----||||||||||-|||--||||||-- 0 [O] COG0425 Predicted redox protein, regulator of disulfide bond formation |||---|||||||-|-||||-|-----||-|-----||----|||-|-||---------||----- 0 [S] COG0432 Uncharacterized conserved protein |||||||||||||---||||-|-----||---|----|----||||---|-|---|---|||||-- 0 [R] COG0433 Predicted ATPase -----------------|||||||--||||||-|--||----|||||-|-||-------||-|--- 0 [G] COG0448 ADP-glucose pyrophosphorylase ||-|--||||------||-|----||-||||-----||----------||-----||||------- 0 [D] COG0455 ATPases involved in chromosome partitioning ||||||||||||||||--||-|----||||------||-----------|-----|--|||-|--- 0 [O] COG0464 ATPases of the AAA+ class --|----------||-||--||||||----|-----|||||||||||||||||||||||||||||| 0 [O] COG0466 ATP-dependent Lon protease, bacterial type ||-|--||-||--||-|-|--|||--|---|||||-||----|||||-||||||||||||||---- 0 [P] COG0471 Di- and tricarboxylate transporters ||-|||--|||||||-|-||-|||--||||----|-||----|||||-|||||||||||||||||| 0 [C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit --------|-------|----|-----||||||---|----------------------------- 0 [P] COG0490 Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels |||------|---||-|||||--|--|||||---|-||----||||||||||||||||||-|||-- 0 [H] COG0502 Biotin synthase and related enzymes ---|---------||---||-|----|||-----|-||----|||||--|-|-|||||||||||-- 0 [E] COG0506 Proline dehydrogenase --|----------||-|-||||----|||-----|-||----|||||-||--||||||-|||||-- 0 [R] COG0523 Putative GTPases (G3E family) -------||---|||-|-|--|-----||-|-----||----||||||||--|--|--|-||||-- 0 [P] COG0529 Adenylylsulfate kinase and related kinases ||||||||||||-||-|||-----||-----------|----|||||-|--|--------|----- 0 [P] COG0530 Ca2+/Na+ antiporter |||||||||||||---||||-|-----||-||--|-||-----------|-----|----|-|--- 0 [R] COG0535 Predicted Fe-S oxidoreductases ---|||||--|-|-----|------------||||-----|-|||-|--||---------|----- 0 [E] COG0549 Carbamate kinase ||||||||||||------||-|-----||-|------|----|||||-||||||||---|||||-- 0 [O] COG0555 ABC-type sulfate transport system, permease component -|------|-|||----|||||----|------|---|----|||||--|-----|--|||||--- 0 [E] COG0559 Branched-chain amino acid ABC-type transport system, permease components -------------||------|||--||||----|-||----||||||||||||||---||||||| 0 [C] COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes ----|--||---|----||||-----|||-|---|--|-||||||-|-||--||||||||||||-- 0 [R] COG0579 Predicted dehydrogenase |-|||||||--||||---|-|--|--|------||-||----|||||-||||-||||||||||-|| 0 [ER] COG0591 Na+/proline symporter -||-----||-------|||||||--|---|--||-||----||||---|||---|---|||||-- 0 [P] COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component |||||||||||||---|-||----------|---|-||----|||||-|||||||||||||||||| 0 [R] COG0603 Predicted PP-loop superfamily ATPase |||||||||||||---|-||------||||------||----||||||||||||||--|----|-- 0 [H] COG0611 Thiamine monophosphate kinase ||||----|--||---||||-|--------|------|----|||||-||||-|||---------- 0 [R] COG0613 Predicted metal-dependent phosphoesterases (PHP family) |||||||||||||---||||||-||-|||||---|-||----|||||||||||||||||||||||| 0 [J] COG0621 2-methylthioadenine synthetase -------------||---||-|----|||-----|-||----|||||-||-|||||---||||||| 0 [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases |-||||-----|-||---||-------||||------|----|||||-||-|||||---||||||| 0 [R] COG0661 Predicted unusual protein kinase |||---||||------|||||------||-------||----|||||-||--||||||-|||||-- 0 [G] COG0662 Mannose-6-phosphate isomerase |||-||||-|-|----|-||-|----|||-|-----||----|||-|-||--||||--|||||||| 0 [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily ||----||--|------|------------|---|-------|||||-||-||--|---||-|--- 0 [M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase -|-|----|-|||----|||||----|------|---|----|||||--|-----|--|||||--- 0 [E] COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component |||-----||---|-------|----||||-------|----|||||-||||---|---||-|--- 0 [H] COG0684 Demethylmenaquinone methyltransferase ||||----||---||-----||||---||||-----||----|||||-|||||||||||||||-|| 0 [I] COG0688 Phosphatidylserine decarboxylase -------------|||--||-|-----||-----|-||----|||----|-----||||------- 0 [R] COG0699 Predicted GTPases (dynamin-related) ------------------|-----------|-----||----|||-|-||-----|---------- 0 [S] COG0700 Uncharacterized membrane protein -||-----||---||--|||||||--|---|--||-||----||||--||||---|---|||||-- 0 [P] COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components |||||||||||||---|-||--||--|||||------|----||||||-||||||||||||||||| 0 [F] COG0717 Deoxycytidine deaminase ||||||||||||----||||----------|---|-||----|||||-|||||||||||||||||| 0 [H] COG0720 6-pyruvoyl-tetrahydropterin synthase --||||----|||||-|-||-|----|||||-----||----------||--|||||||||||||| 0 [C] COG0723 Rieske Fe-S protein -------------|----------------------|-----|||-|---|-|||-|||--|-|-- 0 [G] COG0738 Fucose permease --|-----|-|-|---|-||-|----||||----|-||----|||||-|||||||||||||||||| 0 [O] COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component -----------------|||||----|||||-----||-------|-||||||--|||||||||-- 0 [E] COG0757 3-dehydroquinate dehydratase II ----------------|||||||||-|||||-----||----||||||||||||||||||||||-- 0 [IM] COG0761 Penicillin tolerance protein ----------|-|---||||-------------||-||----|||||-|||||||||||||||||| 0 [R] COG0780 Enzyme related to GTP cyclohydrolase I |-|---|||-|-|---||||||--|-||||--||--||------------||----||-||||--- 0 [O] COG0785 Cytochrome c biogenesis protein ------------------|-|-----|-------|-------|||||-|||--||-||-------- 0 [E] COG0786 Na+/glutamate symporter ---|------------|-||-|----|||-------||----|||-|-|||||--|||||||-|-- 0 [F] COG0788 Formyltetrahydrofolate hydrolase -----------------|||----|-----||||--||----|||||-||||||||||-|||||-- 0 [G] COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase --------------|---||-|----|||-----|-|||----|||---||----|||-||||--- 0 [E] COG0804 Urea amidohydrolase (urease) alpha subunit ----||--|----||-||||||||--||||||-||-||----||||||||||||||||||||||-- 0 [H] COG0807 GTP cyclohydrolase II ----------------|||||||||-|||||-----||----||||||||||||||||||||||-- 0 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis --------------|---||-|----|-------|--||----||----||----|||-||||--- 0 [O] COG0829 Urease accessory protein UreH --------------|---||-|----|||-----|--||----|||---||----|||-||||--- 0 [O] COG0830 Urease accessory protein UreF --------------|---||-|----|||-----|-|||----|||---||----|||-||||--- 0 [E] COG0831 Urea amidohydrolase (urease) gamma subunit --------------|---||-|----|||-----|-|||----|||---||----|||--|||--- 0 [E] COG0832 Urea amidohydrolase (urease) beta subunit --|-------------||||||---|----|---|-||----|||||-|||||||||||||||||| 0 [V] COG0841 Cation/multidrug efflux pump --|---------------||-|-----||||------|----|||||-||--||||||||||||-- 0 [P] COG0855 Polyphosphate kinase -|||||----|----------|---||---|-----|-|----||-|---|---|-|||----|-- 0 [V] COG1002 Type II restriction enzyme, methylase subunits -|||---||--|----|-||------|||---|---||----|||||-||-||--|--|||||||| 0 [M] COG1004 Predicted UDP-glucose 6-dehydrogenase -------------||-|----|----|-------|-||----|||||-||--|--|--|-|----- 0 [C] COG1017 Hemoglobin-like flavoprotein ---|---------||-----||----|||-----|-||----||||||||--||||---|||||-- 0 [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 ---------------------------||-------|-----|||||-||-----------|---- 0 [Q] COG1021 Peptide arylation enzymes ---|------------|----|-----||--|----||---------------------|--|--- 0 [G] COG1023 Predicted 6-phosphogluconate dehydrogenase ---|||--|-|||||-|--|||----|||||-|||-||----|||||-||--|--|---||||||| 0 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase ----||-----------|-|------|---|-----||----|||||-||||-||-||||-|---- 0 [E] COG1027 Aspartate ammonia-lyase --|-|||||-|-|---|-----------------|-||-----------|-----|----|-|--- 0 [O] COG1030 Membrane-bound serine protease (ClpP class) |||-|||||||||----|||||-----||-||-----|----|||-|-||------------|--- 0 [C] COG1032 Fe-S oxidoreductase -|||--||||-------|------||-----------|-----------|--------|------- 0 [R] COG1033 Predicted exporters of the RND superfamily ||||||--|||-|---||||||||---||||------|----|||||-|-------|||------- 0 [HR] COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes -----------|-||---||------||||-------|----|||||--||--|||---|||||-- 0 [C] COG1062 Zn-dependent alcohol dehydrogenases, class III --|-||----|||||---||------||||-||||-||----|||-|--|--|||||||||||--- 0 [R] COG1064 Zn-dependent alcohol dehydrogenases ||||||||||-------|------|-----|-----||----|||||-||||-------------- 0 [O] COG1067 Predicted ATP-dependent protease -------------|--------------------|-||----|||||------------||||--- 0 [C] COG1069 Ribulose kinase --------|----||---||-|----|---|---|-||-|--------||--|--|---------- 0 [R] COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold -|---------------|--|---|-|---|--||-||----------||-||||||||-|||||| 0 [MG] COG1086 Predicted nucleoside-diphosphate sugar epimerases |-|--||||--||-|---||||----|||||||---||----|||||--|||||||---||-||-- 0 [M] COG1088 dTDP-D-glucose 4,6-dehydratase |-||-||||--||---|-||||----|||||||---||----|---|--|--||||---||-|||| 0 [M] COG1091 dTDP-4-dehydrorhamnose reductase |||||-||||-|-||||||-|------||||---|---|||||||-|--|--|---|--------| 0 [L] COG1112 Superfamily I DNA and RNA helicases and helicase subunits --------------------|-|||-|---|-|||-|-----|||||-||||-------------- 0 [E] COG1114 Branched-chain amino acid permeases --|---||------------|||||-|-----|||-||----|||-|-||||-||-|||-||---- 0 [E] COG1115 Na+/alanine symporter -||-||--||||-----|||||||--|---|--||-||----||||---||||--|---|||||-- 0 [P] COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component ------------------||-------||--------|----|||||-||--||||||||||||-- 0 [P] COG1118 ABC-type sulfate/molybdate transport systems, ATPase component |||-|----|-|------|||-----||||----|-------|||||-|------|||-||-|--- 0 [R] COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase --|--|--------------|-||--------|-|--|||--|||||------------||||--- 0 [EP] COG1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component -----------------|--|---|||----|----||-|--|||||-||||---|---|||||-- 0 [G] COG1129 ABC-type sugar transport system, ATPase component |--|||--|-|||-------||---------|----||----|||------|-||||||------- 0 [C] COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain ----------|-|-------------|||-----|-|-----|||-|--|-----|-----|---- 0 [C] COG1140 Nitrate reductase beta subunit |||-|||||||||----|||||--------|-----|-----|||||-|||||||||||||-|--- 0 [C] COG1145 Ferredoxin -----------------|--|-----|--|-|----||----|||||-||||---|---|||||-- 0 [G] COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components ---|--||--|-|-----||||--|-|------|---|----|||||-||||-|||--|||||--- 0 [P] COG1178 ABC-type Fe3+ transport system, permease component -------------||-----|---------|---|-||----|||||-|||||||||||------- 0 [H] COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 ||||----||---||-----|-||-|-||||-----||-----------|--|||||||||||-|| 0 [I] COG1183 Phosphatidylserine synthase |||---|||-|||---||--|-----------|----|----|||||----|-------------- 0 [R] COG1203 Predicted helicases |||---||||||-||----|-|----|||-------||-----||---------------|----- 0 [R] COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster |||||||||||||||||-||-|----|||||-----||-------||--|--||||--||||||-- 0 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) |-|||||||--||----|||-|----|||||||---||----|||||--|--||||---||-||-- 0 [M] COG1209 dTDP-glucose pyrophosphorylase --||||----|||||-||||-|----|||||---|-||----|||||-||||||||||||||||-| 0 [O] COG1225 Peroxiredoxin |--||||-|--|-|---|--||-----||-|-|-|-||-------||-||-----|---|||||-- 0 [Q] COG1228 Imidazolonepropionase and related amidohydrolases ------------------||-|----|||-------|------------|-----|------||-- 0 [E] COG1231 Monoamine oxidase --||------------|----|-----|||------||----||||||||-|-|||---------- 0 [E] COG1246 N-acetylglutamate synthase and related acetyltransferases ---|||--|-|||-------||-----||||---|-||----|||||-||-----|---||||||| 0 [I] COG1250 3-hydroxyacyl-CoA dehydrogenase --|-------------|----------||-|---|-||----|||||--|-----|---||-||-- 0 [C] COG1251 NAD(P)H-nitrite reductase --|-----------|---||--||---||-------||----------||-|||||---|||||-- 0 [S] COG1262 Uncharacterized conserved protein --------|------------------||-------||-----------|---------||-|--- 0 [S] COG1273 Uncharacterized conserved protein -|--|-|||----||-----------|||--||||-------|||-|-|-||-|------------ 0 [P] COG1275 Tellurite resistance protein and related permeases --------------------|-----|||-|---|-||----|||||-||-|---|||-|-|---| 0 [R] COG1279 Lysine efflux permease |-|-||--|||||----||--|----|---------||----|||||-|||||--|--||||||-- 0 [E] COG1280 Putative threonine efflux protein --------------------|----|------|||-||----|||-|---|------------|-- 0 [S] COG1288 Predicted membrane protein ---|||----||||--|-||-|----||||------||----------||--|||||||||||||| 0 [C] COG1290 Cytochrome b subunit of the bc complex |||---||||--|-----||-------||-|---|-||-----------|------------||-- 0 [S] COG1300 Uncharacterized membrane protein --||--||----|---|--||||||||||-|---|-||----|||||-||--|--|--|||-|||| 0 [C] COG1301 Na+/H+-dicarboxylate symporters ----||-----------|------------||----||----|||||---|--------||||--- 0 [G] COG1312 D-mannonate dehydratase -----------------|------||----|------|----------|----------------- 0 [L] COG1315 Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain -----------------|----||||----|-----||----||||||||-----||||---|--- 0 [NU] COG1317 Flagellar biosynthesis/type III secretory pathway protein ----------|||--------|--||-||-------||----|||----|-----|---||-|--- 0 [C] COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs ---------------------|--||||||------||---------------------||||||| 0 [K] COG1329 Transcriptional regulators, similar to M. xanthus CarD |-||||--|-|||---|--|-|||---||-|-----|------------------------||--- 0 [O] COG1331 Highly conserved protein containing a thioredoxin domain ----------------|-||------||||------||---------------|||---------- 0 [O] COG1333 ResB protein required for cytochrome c biosynthesis ----------------||------------|-----||----------||------|||------- 0 [N] COG1334 Uncharacterized flagellar protein FlaG |-------||-|----||-------------------|---------------------------- 0 [L] COG1336 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) |||--|--||||-----|-||------||---|----|---------------------------- 0 [L] COG1343 Uncharacterized protein predicted to be involved in DNA repair --|---||------------||--------||--|-||----|||||-||||-|||-----|---- 0 [M] COG1346 Putative effector of murein hydrolase |||--||-||||----||---------||--------|---------------------------- 0 [R] COG1353 Predicted hydrolase of the HD superfamily (permuted catalytic motifs) --------|-------||-------------------|---------------------------- 0 [L] COG1367 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) -|--||||-|--||--|-||-|-----|||------|----------------------------- 0 [L] COG1372 Intein/homing endonuclease -----------------|||------|||||-----||----|||-|-||---|||---||||--- 0 [S] COG1376 Uncharacterized protein conserved in bacteria |||||||||||||--------|--------------|----------------------------- 0 [K] COG1378 Predicted transcriptional regulators |||---||-|--------------------------||---------------------------- 0 [S] COG1379 Uncharacterized conserved protein --|---||------------||--------||--|-||----|||||-||||-|||-----|---- 0 [R] COG1380 Putative effector of murein hydrolase LrgA |-|---|---||----|-|--|-----------|--|-----|--|----------|||------- 0 [V] COG1401 GTPase subunit of restriction endonuclease --||----|-|-|||||-||||----|||||-||--||||------|-||--||||--|||-|--- 0 [O] COG1404 Subtilisin-like serine proteases -----------------|------||----|------|----------|----------------- 0 [N] COG1406 Predicted inhibitor of MCP methylation, homolog of CheC -----------------|||-|----|||||------|----|||||-|||-|--|---|||||-- 0 [E] COG1410 Methionine synthase I, cobalamin-binding domain |-||---------|||--||--||||--------|-||----||-----|------------|--- 0 [C] COG1413 FOG: HEAT repeat ---|------------||---|----|||-------||----|||||-||||---|--||||||-- 0 [K] COG1414 Transcriptional regulator -|--------------|-----------------|-|----------------------------- 0 [H] COG1424 Pimeloyl-CoA synthetase ----||--|-|-|---|----|||-------------|------------------|||------- 0 [R] COG1427 Predicted periplasmic solute-binding protein ---------------------------------|--|-----|||-|---||----||--|---|| 0 [M] COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases |||---|||-|||---||-||-----------|----|---------------------------- 0 [L] COG1468 RecB family exonuclease ||||||||||--|----|----------------|-||-----------|--||||---------- 0 [S] COG1469 Uncharacterized conserved protein --|---|||----------------------------|---------------------------- 0 [S] COG1470 Predicted membrane protein |---||--|-|||---||||----------|------|----|||||-||||-------|||-|-- 0 [R] COG1489 DNA-binding protein, stimulates sugar fermentation --|---------------||||----|||||-----||----|||-|-|-||---------|||-- 0 [G] COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins ---------------------|||------------||----|||||-|||||||||||||||||| 0 [O] COG1495 Disulfide bond formation protein DsbB ----------------|-||||||-||||||---|-||----|||||-||||||||--|||||||| 0 [S] COG1496 Uncharacterized conserved protein ---|||||--|||||---|-||------------|-||-----------|--|------|---|-| 0 [E] COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases -||-------------||--||--|-----------||----|||||-|-|||------||-||-- 0 [E] COG1509 Lysine 2,3-aminomutase -|----||--------------------------|-|------------------|---|-|---- 0 [K] COG1510 Predicted transcriptional regulators -----------------|||----|------|----||----|||----|-|---|-----|||-- 0 [R] COG1512 Beta-propeller domains of methanol dehydrogenase type |||-|||||||||---||-|-|----|---|---|-||----|||||--|-----|---|||||-- 0 [J] COG1514 2'-5' RNA ligase ---||||||||||-|-||-|-|--------|-----|-----|||||-----|------------- 0 [L] COG1515 Deoxyinosine 3'endonuclease (endonuclease V) ||||--|||--------|---|---|-|||------|-----|||||-||--|--|-------||| 0 [S] COG1520 FOG: WD40-like repeat |||||||||||||--------|----|||-|-----||----|||||-||||-|||---|||||-- 0 [K] COG1522 Transcriptional regulators --|--------|-----||-||||--|||-|-||--||-|--|||||-||||---|---||-|--- 0 [G] COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases ||-|--||-|---||-|--|------|-------|-|--|||-------|||-||---|||||--- 0 [L] COG1525 Micrococcal nuclease (thermonuclease) homologs |-|-----|------|-|--------|||-|---|--||---|||||-|-||----|||------- 0 [P] COG1528 Ferritin-like protein ----------|||---|----|--|--||-------||----|||----|-----|---||-||-- 0 [C] COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs -||-|-|||||||----||-|------||-|-----||-----------|-----|---|||||-| 0 [L] COG1533 DNA repair photolyase -----------------|------------------|-----|||-|-||-----------|---- 0 [Q] COG1535 Isochorismate hydrolase ------||------------||----|--|----|-||----|||||-|||--|||--||------ 0 [R] COG1540 Uncharacterized proteins, homologs of lactam utilization protein B |-|-----|--|-------|||---------------|----|--|--|---|--|---------- 0 [H] COG1541 Coenzyme F390 synthetase ------||----------||----|--||||------|---------------------------- 0 [S] COG1543 Uncharacterized conserved protein ---|||----|||---|-||-|------------|-||---------------------------- 0 [S] COG1547 Uncharacterized conserved protein -----------------|------||----|-----||----|||||||||||---|||------- 0 [T] COG1551 Carbon storage regulator (could also regulate swarming and quorum sensing) ---|----|-----------||---------|----||----|||------|-||||||------- 0 [S] COG1556 Uncharacterized conserved protein |--|-------|-||---||-|----|||-----|-|---------------||||---|||||-- 0 [I] COG1562 Phytoene/squalene synthetase ----------------|-----------------|-|-----|||||-|||--|||---||||||| 0 [V] COG1566 Multidrug resistance efflux pump ----------------||------||----|-----||----|||||-||-----||||------- 0 [N] COG1580 Flagellar basal body-associated protein -----------------|------||----|-----||---------------------------- 0 [N] COG1582 Uncharacterized protein, possibly involved in motility -|--|||||-|||---||------------|-----||----||||||-|--|--|---------- 0 [E] COG1586 S-adenosylmethionine decarboxylase |||----|||-|-----|-||---------|-----|---------------------|------- 0 [C] COG1592 Rubrerythrin -----------------|--|---|-|----------|----|--||-||||-------||--|-- 0 [G] COG1593 TRAP-type C4-dicarboxylate transport system, large permease component --------||-|----||-------------------|---------------------------- 0 [L] COG1604 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) --|-||||||||-|--||-|||||--||||-|--|-||----|||||-||-|||||--||||||-- 0 [R] COG1611 Predicted Rossmann fold nucleotide-binding protein ------------------||-------|||-------|----|||||--|--||||---|||||-- 0 [P] COG1613 ABC-type sulfate transport system, periplasmic component ---|----||-|---------|---|--------|-||----|||-|-||||-||||||--|---- 0 [C] COG1620 L-lactate permease -------------||--|--------|---|-|||-||-----||---|--|---|---|------ 0 [G] COG1621 Beta-fructosidases (levanase/invertase) -----------------|--|-----|||-|-----||---------------------------- 0 [R] COG1623 Predicted nucleic-acid-binding protein (contains the HHH domain) |-|---||---|----||------------|-----||---------------------||||--- 0 [S] COG1633 Uncharacterized conserved protein ----------------||--|---------|||-|---------------|||||-|||-----|| 0 [S] COG1636 Uncharacterized protein conserved in bacteria -----------------||-|---|-|---------||----|--||-||||---|---||-||-- 0 [G] COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component ------------------||-|--------------|-----||||---------|-----|---- 0 [S] COG1649 Uncharacterized protein conserved in bacteria --|------|---||---||----------------|----------------------------- 0 [I] COG1657 Squalene cyclase |-||||||||--|---------------------|--------||-|-|----------||-|--- 0 [R] COG1661 Predicted DNA-binding protein with PD1-like DNA-binding motif ----------------------||||----|-----|--------|--||--|--||||----|-- 0 [M] COG1664 Integral membrane protein CcmA involved in cell shape determination -------------------|-------||-------||----|||||-||||---|--|------- 0 [S] COG1666 Uncharacterized protein conserved in bacteria --|-----------------|-----|---------|-------------||----||-------- 0 [E] COG1687 Predicted branched-chain amino acid permeases (azaleucine resistance) |||||||||||||--|||-|-|----|||-|------|----|||-|--|-----|---------- 0 [S] COG1690 Uncharacterized conserved protein -----------------|------||----|-----||------------------|||------- 0 [S] COG1699 Uncharacterized protein conserved in bacteria ---||||||--||--------|----||||-------|----|||----------|-------|-- 0 [E] COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family |||---|||||||---||------------|---|-----------|---|--------||----| 0 [R] COG1708 Predicted nucleotidyltransferases ----------||-||---||-|||--|||||------|--------------|------------- 0 [T] COG1716 FOG: FHA domain -----------------|------||----|-----||---------------------------- 0 [S] COG1728 Uncharacterized protein conserved in bacteria ----------------|-----||||----|-----||----||||||||||||||--|||||||| 0 [T] COG1734 DnaK suppressor protein --||----|-|-|----|--||||-||-------|-|-----|||||-||||-||----||||--- 0 [S] COG1738 Uncharacterized conserved protein --|---------------|--------||-----|-||----|||-|--|-----|---||-||-- 0 [S] COG1742 Uncharacterized conserved protein ----|||-|-|-|||---||-|-----------|---|----------|--|----|||||||--- 0 [E] COG1748 Saccharopine dehydrogenase and related proteins -------------||||||-|---|--|||-|----||----|||-|-||--||||---||||||| 0 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily ---------------------|-----||---|||-||------------||-||----------- 0 [S] COG1755 Uncharacterized protein conserved in bacteria ---|--||----|-------|----|----|---|-||-------||-|-||-||-|||------- 0 [C] COG1757 Na+/H+ antiporter ---------------------|----||||-||||-|--||||||||------------|-|---- 0 [F] COG1780 Protein involved in ribonucleotide reduction --||---|-----||--|-|-|----|-------|-||----||||---|--|--|-----|---- 0 [P] COG1785 Alkaline phosphatase -----------------||--|---------------|------------------||-------- 0 [V] COG1787 Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes --------|--|--------||----|||-|-|---||----|------||----|||-|||||-| 0 [I] COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit -------------||-|--|----------------|------------|--|------------- 0 [S] COG1791 Uncharacterized conserved protein, contains double-stranded beta-helix domain |||||||||||||||||----------||-------||----------|||--||---|||-||-- 0 [L] COG1793 ATP-dependent DNA ligase ------|||----------------------|----|-----|||||----|---|--|||-||-- 0 [M] COG1794 Aspartate racemase ------|||-------|-|||---------|-----|-----|||||--|--||||---|||||-- 0 [M] COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family ||-------|----------------|---------|----------------------------- 0 [S] COG1809 Uncharacterized conserved protein |||------|---|----|--|-----||||-----|------||||-||------------|--- 0 [GC] COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase -------------------------|--------|-|-----|||||-|-||------|------- 0 [R] COG1823 Predicted Na+/dicarboxylate symporter --|---------|-----||-------||-|-----||-----------|----------|-|--- 0 [E] COG1834 N-Dimethylarginine dimethylaminohydrolase |||||||||-|-------||-----------------|---------------------------- 0 [S] COG1836 Predicted membrane protein |||---|||||-----||------------|------|----|||||-||--||||-----||--- 0 [C] COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain --||------|-|-----|||-----|-----|||--|-----||||-||||||||--|||||--- 0 [P] COG1840 ABC-type Fe3+ transport system, periplasmic component -||---|||---------||----------------|-----------------------|-|--- 0 [G] COG1850 Ribulose 1,5-bisphosphate carboxylase, large subunit -|------------------|---|-----|-----|--------------------------|-- 0 [M] COG1861 Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog -||||||||||||-----------------------||---------------------------- 0 [S] COG1865 Uncharacterized conserved protein ------------||------||------------|-||----|||||-||||------|||||--- 0 [C] COG1866 Phosphoenolpyruvate carboxykinase (ATP) -----------------|--------|----|--|-||-|--|||||-|-||-------------- 0 [G] COG1869 ABC-type ribose transport system, auxiliary component --||--|||--------|-------|----|-----||----------||-----|---||--|-- 0 [NT] COG1871 Chemotaxis protein; stimulates methylation of MCP proteins ||||||||||--------------------|-----||---------------------------- 0 [S] COG1873 Uncharacterized conserved protein ------||---------|------------|--|--||-------|------|-------|--|-- 0 [G] COG1874 Beta-galactosidase -----------------|----||--||||------||----------||--|--|---------- 0 [T] COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH ||||||-||-||-----|||------|||-----|--|-----------|||---|---||-|--- 0 [R] COG1878 Predicted metal-dependent hydrolase --|--------------|--|---|-|--|||----||----|||||-||||---|---|||||-- 0 [G] COG1879 ABC-type sugar transport system, periplasmic component |-|||||||--|-|--|-----||--|||||---|-|-|---|||-|-|--|||||||-||-|--| 0 [R] COG1881 Phospholipid-binding protein ---||||||--||--------|----||||-------|----|||----------|---|||||-- 0 [I] COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit -----------------|------------||-|--||----|||||-|---------||||---- 0 [E] COG1897 Homoserine trans-succinylase |-|--||||--||-----||||----|||||||||-||----|---|--|-|||||--||||||-- 0 [M] COG1898 dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes -----------------|--------|---||----||----|||||-------------||||-- 0 [G] COG1904 Glucuronate isomerase -|||||--|-|-------------------|-----|------------------|---------- 0 [P] COG1910 Periplasmic molybdate-binding protein/domain --||||-----|-----|-|||------|-|--|---|----|||||-|||--|||||----||-- 0 [L] COG1943 Transposase and inactivated derivatives |||---|||||-----||------------|------|----|||||-||--||||-----||--- 0 [C] COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain -----------||||---------------------|-----|||||--|-----|----||||-- 0 [FH] COG1953 Cytosine/uracil/thiamine/allantoin permeases -----------|-||----|-|----|||-----|--|----|||-|--|-|---|--||||||-- 0 [F] COG1957 Inosine-uridine nucleoside N-ribohydrolase ---|||--|-||||-----|||----|||||---|-||----|||||-||---|||---|||||-- 0 [I] COG1960 Acyl-CoA dehydrogenases --|----|--|-|---|---|-----|||-||----||----|||||-||||-||||||------- 0 [T] COG1966 Carbon starvation protein, predicted membrane protein |--------|||----||||||---||||||||||-||----||||||||--||||--||||||-- 0 [V] COG1968 Uncharacterized bacitracin resistance protein |-|-----------------|-----|---|-----||----|||||--|--|||---|------- 0 [S] COG1971 Predicted membrane protein -------------------|------------|-|-||----|||||-|-||----||-----|-- 0 [F] COG1972 Nucleoside permease ----------|||--------|-----||-------||----|||----|-----|---|||||-- 0 [O] COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family ----------------||------------|-----|----------------------------- 0 [S] COG1978 Uncharacterized protein conserved in bacteria ------||-----|------||----||||----|-||----|||||-|||--|||--||---|-- 0 [E] COG1984 Allophanate hydrolase subunit 2 ||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||-- 0 [H] COG1985 Pyrimidine reductase, riboflavin biosynthesis ||--||--|||||------------------------|----|||||-|----------------- 0 [S] COG1986 Uncharacterized conserved protein ----------------|-|||----------------|----|||||-||-|||||||||||||-- 0 [H] COG1995 Pyridoxal phosphate biosynthesis protein ---|------|-|||-|----|--------------||----------||--||||--|||||||| 0 [R] COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems ---|||--|-|-|||------|||---|||----|-||----|||||-||--|||||||||||||| 0 [C] COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit --|-----|---------||-|----||||------||----------||---|||||||||||-- 0 [C] COG2010 Cytochrome c, mono- and diheme variants ----------------|-||||----|||||-----||----|||||-||--||||--||||||-- 0 [H] COG2022 Uncharacterized enzyme of thiazole biosynthesis ---|||--|-|||||--|--||----|||||-----||----|||-|--|--||||---|||||-- 0 [C] COG2025 Electron transfer flavoprotein, alpha subunit --|---------------||-|----||||------|-----|||||-||||||||---------- 0 [M] COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) ---|----|--|-||-----||----||||----|-|-----|--||-||-----|---|||||-- 0 [I] COG2030 Acyl dehydratase --------|---|-------|-----|-----|----|----|------||-----||-------- 0 [I] COG2031 Short chain fatty acids transporter --|----------||-|----|-----||||-----|-----|||||-|--|-|||----||-|-- 0 [P] COG2032 Cu/Zn superoxide dismutase |--|-------------|--|---|||-----|||--|----------|----------------- 0 [S] COG2035 Predicted membrane protein |||||||||||||-----||||----|||||------|----|||-|-||-----|---|||||-- 0 [H] COG2038 NaMN:DMB phosphoribosyltransferase ------||---|--------||-----||---|||-||-------|---------|---------- 0 [O] COG2039 Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) -------------||---|--------||||-----|-----|----------------|--|--- 0 [E] COG2040 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) --||||--|-|||---|--|-|----|||-------|-----|||||--|-|---|--||||||-- 0 [R] COG2041 Sulfite oxidase and related enzymes ||--||---|-------|||-|--------|-----|------------------|---------- 0 [HR] COG2045 Phosphosulfolactate phosphohydrolase and related enzymes -------||-|||||-|-||-|--------------||--------------------|------- 0 [P] COG2046 ATP sulfurylase (sulfate adenylyltransferase) ------||-----|------||----||||----|-||----|||-|-|||--|||--||---|-- 0 [E] COG2049 Allophanate hydrolase subunit 1 -----------------|||----------|-----||---------------------------- 0 [S] COG2052 Uncharacterized protein conserved in bacteria ||----||-|----------------|---|-----|-----|||-|--|||-------||||--- 0 [C] COG2055 Malate/L-lactate dehydrogenases --------------------|-------------|-||----------||||-||-|||------- 0 [R] COG2056 Predicted permease -----------|--------||----|||-|-|---||----|------||----|||-|||||-| 0 [I] COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit -|---------------|||||---||---------||-|--------||-----|---||-||-- 0 [P] COG2059 Chromate transport protein ChrA ------------------|||-----|---------||----|||||-||-----|---|||||-- 0 [E] COG2066 Glutaminase |--------||||--------|-----||-------||----|||----------|---||-||-- 0 [R] COG2068 Uncharacterized MobA-related protein -------------||---|--|----||||------||-----------|-----|---||-||-- 0 [P] COG2072 Predicted flavoprotein involved in K+ transport |---||----||||------------|||-------||----|||-|--|-----|---||-|--- 0 [R] COG2079 Uncharacterized protein involved in propionate catabolism ----------|||--------|--||-||-------||----|||----|-----|---||-||-- 0 [C] COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs ---|||--|-|||||--|--||----|||||-----||----|||-|--|--||||---|||||-- 0 [C] COG2086 Electron transfer flavoprotein, beta subunit -||-----------------|---|-----|-----|----------------|--|||----|-- 0 [M] COG2089 Sialic acid synthase -------------||---||----------|---|-||----|||-|---|||--|---------- 0 [H] COG2091 Phosphopantetheinyl transferase -||-|||||||||---|--|-||||-----------|-----||||||||-|||||--||||||-- 0 [U] COG2095 Multiple antibiotic transporter ------------------||-|--------||--|-||----|||||-|-||--------|-|--- 0 [R] COG2103 Predicted sugar phosphate isomerase |-|||||||-------|-||||----|||||-----||----||--|-||--||||--||-|||-- 0 [H] COG2104 Sulfur transfer protein involved in thiamine biosynthesis -||---|---||------||-|--------------||----|||||-||-----|---------- 0 [S] COG2105 Uncharacterized conserved protein ----||--|-|||---|----|||-------------|------------------|||------- 0 [R] COG2107 Predicted periplasmic solute-binding protein -----------------|-------------|----||----|||||---|--------||||--- 0 [G] COG2115 Xylose isomerase --|---||-|-|-|||-----|----||||----|-||----|--|-------------||||--- 0 [S] COG2120 Uncharacterized proteins, LmbE homologs ---|---------||---||-|----|||||-----||-----------|--|--|--||||||-- 0 [Q] COG2124 Cytochrome P450 --|-----|----------|-|----|||||--||-||----|||||--|---|||---|||||-- 0 [S] COG2128 Uncharacterized conserved protein ---|---------||----|--------------|-|-----|||-|--|-----|------||-- 0 [R] COG2130 Putative NADP-dependent oxidoreductases ---|------|--||-|--|------|||-------||----|||||--|||||||--||||||-- 0 [Q] COG2132 Putative multicopper oxidases ----------|-------||-|---|-|||-------|----|||-|--|--|--|---||-||-- 0 [G] COG2133 Glucose/sorbosone dehydrogenases ---|---------|-----|------||||------|-----|||-|--|---------||||--- 0 [S] COG2135 Uncharacterized conserved protein ||||----||||------||-|----|||-----|-||-----------------|---------- 0 [S] COG2138 Uncharacterized conserved protein --|---|||---------|-----------------|---------|--------|---||-|--- 0 [GR] COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzymes --||||----||--|---||-|----||------|-||----|||||--|--|--|---||-||-- 0 [PR] COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases ---|-------------|||||----|---|--||-||----|||-|-||||||||--||||||-- 0 [M] COG2148 Sugar transferases involved in lipopolysaccharide synthesis --------------|---|-------|||--|-----|----|||-|-||-----------|---- 0 [R] COG2153 Predicted acyltransferase --|-------------------||------|-----||----------------------|-|-|- 0 [S] COG2155 Uncharacterized conserved protein -----------------|------------|-----||----|||||-------------|----- 0 [G] COG2160 L-arabinose isomerase ---|-------------|||-------||----||-------|||-|-|----------|-----| 0 [D] COG2161 Antitoxin of toxin-antitoxin stability system ---------------------------||-----|-||----|||-|--|------------||-- 0 [Q] COG2162 Arylamine N-acetyltransferase ||----||-|||||||--------------|------|---------------------------- 0 [J] COG2163 Ribosomal protein L14E/L6E/L27E --------|-|-|-------------|||-----|-|-----|||-|--|-----|-----|---- 0 [C] COG2180 Nitrate reductase delta subunit --------|-|---------------|||-----|-|-----|||-|--|-----|-----|---- 0 [C] COG2181 Nitrate reductase gamma subunit ---||||||--||-------||----||||-------|----|||----------|---|||||-- 0 [I] COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) --||--|||--------|-|----||----|-----||----|||||-||--|--|--|||-||-- 0 [NT] COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain |-||----|-----|-||||-|-----||||---|-||----|||---||-----|---|||||-- 0 [T] COG2203 FOG: GAF domain ----------------|---|-||||-----------|----|||||-||-||||||||||||||| 0 [T] COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains ----------------||-|-|--||----|------|----------||-----|---|--|--- 0 [T] COG2206 HD-GYP domain --||||--|-||----|---|-------------|-|----------------------------- 0 [S] COG2210 Uncharacterized conserved protein ------------------|||---------||----|-----|||||----------------|-- 0 [G] COG2211 Na+/melibiose symporter and related transporters ----------------|---------||||----|-||----|||-|--|-----|----||-|-- 0 [P] COG2223 Nitrate/nitrite transporter -----------|-||------|----||||-------|----|||||-||-----|---|||||-- 0 [C] COG2224 Isocitrate lyase ----------||-|-------|----||||-------|----|||||-||-----|---|||||-- 0 [C] COG2225 Malate synthase |-||--||||---||-|--|-------||-|-----||----|||-|-||--|----------|-- 0 [R] COG2234 Predicted aminopeptidases |----------------||||-|||||||-|---|-||||-----|--||--|||----||||||| 0 [P] COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain) -|----||----------------------------|----------------------------- 0 [M] COG2247 Putative cell wall-binding domain -----------------|------|-----|-----||-----------|------|||----|-- 0 [S] COG2257 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB ---|-------|-||----|-|----||||----|-||----|||||-||||-|||---|||||-- 0 [S] COG2259 Predicted membrane protein -------------------|-|----||||-||||-|-----|||||--|-----|---|||||-- 0 [S] COG2261 Predicted membrane protein ------------------||------|----|----||----|||-|--|------------|--- 0 [S] COG2268 Uncharacterized protein conserved in bacteria ----------------------||-------||-|-|-----|||||-||||------|-----|| 0 [G] COG2271 Sugar phosphate permease --------------|------|----|||-|---|-|---------|--------|-------|-- 0 [I] COG2272 Carboxylesterase type B -------------||--|---------||-|-----||---------------------||-||-- 0 [G] COG2273 Beta-glucanase/Beta-glucan synthetase ------------------||----------||-|--||||||-||||-||--||||----|-||-- 0 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain ||-|-----|---------|-|-----|||----|-------||||---|-----|--||||||-- 0 [E] COG2303 Choline dehydrogenase and related flavoproteins --|-----|--||-----||||---|||||------||----|--||-||------------|--- 0 [R] COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain ------||-------------|----|||-----|------------------------------- 0 [S] COG2306 Uncharacterized conserved protein ------------------|--|--------|-----|------|||-------------------- 0 [T] COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 ---|-----------------|----|---------||----|||||-----|----------|-- 0 [S] COG2311 Predicted membrane protein ---|-----------------|-----||-------||----------------------|--|-- 0 [R] COG2312 Erythromycin esterase homolog -||---------------||-|---|-||--|--|-||-----------|-----|---------- 0 [S] COG2314 Predicted membrane protein ------------------|--|--------------||-----------|---------||||--- 0 [S] COG2318 Uncharacterized protein conserved in bacteria --||-----------------|-----|||------||----------||---------------- 0 [S] COG2320 Uncharacterized conserved protein -------------------|||--------||-|--||----|||-|-------------|----- 0 [S] COG2323 Predicted membrane protein --|---------------|-||--------------||----|||||-||---|||---|||||-- 0 [R] COG2334 Putative homoserine kinase type II (protein kinase fold) -------------------|-|---------------|----|||--------|||---|------ 0 [T] COG2336 Growth regulator ----||------------||-|----||||-------|-------|--|----------------- 0 [K] COG2345 Predicted transcriptional regulator ------------------|--|----||||----|-||-----------------|--||||||-- 0 [R] COG2346 Truncated hemoglobins --|------------------|--||------|||------------------------------- 0 [V] COG2348 Uncharacterized protein involved in methicillin resistance ------------------||||----|---|-----|-----|||||-||||-|||---|||||-- 0 [S] COG2350 Uncharacterized protein conserved in bacteria --------------|------|--------------||----|||-|--|-----|--||||||-- 0 [R] COG2351 Transthyretin-like protein ---------------------|--------------|-----||||||||---------------- 0 [L] COG2356 Endonuclease I ---|----|---|-----|--|---------------|----------||-|--------||--|| 0 [R] COG2358 TRAP-type uncharacterized transport system, periplasmic component -----------------|---|--------|-----||---------------------------- 0 [S] COG2359 Uncharacterized protein conserved in bacteria ---------------------|----|---|-----||------------||-------------- 0 [S] COG2364 Predicted membrane protein --------|-||---------|--------------||-------||--|-|-------------- 0 [Q] COG2368 Aromatic ring hydroxylase ------------------||-|----|-------|--||----|||---||----|||-||||--- 0 [O] COG2371 Urease accessory protein UreE ------------------||||--------|-----||---------------------------- 0 [D] COG2385 Sporulation protein and related proteins ---|||---|||-----|---|------------|-------|||||-||--|--|--|||||--- 0 [R] COG2391 Predicted transporter component --||-------||-------|---------------|-------------------|||------- 0 [R] COG2404 Predicted phosphohydrolase (DHH superfamily) |-||||--|||||||-----------|-------|----------|---|-----|---||||--- 0 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog ------|||---|------------------------|---------------------------- 0 [S] COG2426 Predicted membrane protein |||----||-|-----|-----------------|-||---------------------------- 0 [S] COG2445 Uncharacterized conserved protein -------||--------|--|---------||-|---|---------------------------- 0 [S] COG2461 Uncharacterized conserved protein -------------------|------------|-|---|-----------||----||-------- 0 [R] COG2503 Predicted secreted acid phosphatase --|---||||||-----||-|---------||-----|----------|--------------|-- 0 [R] COG2509 Uncharacterized FAD-dependent dehydrogenases ------------------||--------------|-|------------|-----|--||--|--| 0 [V] COG2602 Beta-lactamase class D --|-----------------|-----|---|-|-|-||----|||||-||||-|||---------- 0 [GE] COG2610 H+/gluconate symporter and related permeases ------------------|-----------|-----||-----------|-----|---------- 0 [R] COG2715 Uncharacterized membrane protein, required for spore maturation in B.subtilis. ---|--------------------------|-----||----|||||-||----------|-|--- 0 [S] COG2718 Uncharacterized conserved protein ---|--------------------------|-----||----|||||-||----------|-|--- 0 [S] COG2719 Uncharacterized conserved protein ---------------------|----|---|-----||-----------|---------------- 0 [V] COG2720 Uncharacterized vancomycin resistance protein ----|------|------------------|-----||----|||||--------|--||||||-- 0 [G] COG2721 Altronate dehydratase ------||-----||--|-|----------|-----||--------------|--|---------- 0 [G] COG2730 Endoglucanase ------------------------------|-----|-----|||||------|------------ 0 [K] COG2732 Barstar, RNAse (barnase) inhibitor ----------------||------------|-----||----|||||-||-----|---------- 0 [KNU] COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor) ---|--------------------------|-----||----|||||-||----------|-|--- 0 [T] COG2766 Putative Ser protein kinase --|-----|-------|-||-|--------------|-----------||-----|---||-|--- 0 [T] COG2770 FOG: HAMP domain -------------|-------|--------------||-----------|--|--|------||-- 0 [K] COG2808 Transcriptional regulator ---------------------|--------|--|--|------||-|--|---|----||---|-- 0 [R] COG2819 Predicted hydrolase of the alpha/beta superfamily --------------------------|||--|-|---|-|--|||--------|||---||--|-- 0 [L] COG2826 Transposase and inactivated derivatives, IS30 family ------------------------------------|-----|||---||--||||---||-|--- 0 [S] COG2828 Uncharacterized protein conserved in bacteria --------------------||-----------||-------|||-|-||||-||----|||---- 0 [S] COG2832 Uncharacterized protein conserved in bacteria -|||----|-------|----|--||----|-----||----|||||-|||||||||||||||||| 0 [M] COG2834 Outer membrane lipoprotein-sorting protein -------------------|-|------------|-||---------------||----------- 0 [S] COG2839 Uncharacterized protein conserved in bacteria ------------------------------|---|-------|||||---|--|||----|----- 0 [D] COG2846 Regulator of cell morphogenesis and NO signaling --------------------|-||------------|--------||--|---||---|------- 0 [S] COG2849 Uncharacterized protein conserved in bacteria ------------------------------------|-----|||||--|||||||---------- 0 [S] COG2850 Uncharacterized conserved protein --------------------------|-----|-|-||-----------|--|||---|------- 0 [C] COG2851 H+/citrate symporter -------------||-|-------------------||----------||--|||||||||||||| 0 [C] COG2857 Cytochrome c1 ---|------||---------|----|----||---||----|||||-||||---|--||||||-- 0 [S] COG2860 Predicted membrane protein -------------------------|-----------|----|||-|--|||------|||-||-- 0 [S] COG2861 Uncharacterized protein conserved in bacteria --|----------||---|-----------------||----|||||--|---|||-------|-- 0 [E] COG2866 Predicted carboxypeptidase --|-||||--||||---|--||--------|------|----------||-----|---||||--- 0 [R] COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain -----------------|------|-----|-----||----||||||||-----|---------- 0 [NUO] COG2882 Flagellar biosynthesis chaperone |--|------|||||-|--|-|----||||-------|----|||||-||-----|---|||||-- 0 [P] COG2897 Rhodanese-related sulfurtransferase --------|-------|---------|----------|----------||---------------- 0 [T] COG2905 Predicted signal-transduction protein containing cAMP-binding and CBS domains ---|---------------||-||-------------|-----------|--||||---||-|--- 0 [S] COG2928 Uncharacterized conserved protein --------------------|----------||-|--------|--|--||||||----|||||-- 0 [K] COG2932 Predicted transcriptional regulator ------------------------------------|-----------|---|||----------- 0 [L] COG2946 Putative phage replication protein RstA --||--------------||-------||--------|----|||||-|---|------|||||-- 0 [S] COG2968 Uncharacterized conserved protein --------------------|-----|-------|--|----||||--|--|-||--------|-- 0 [H] COG2978 Putative p-aminobenzoyl-glutamate transporter ---|||--------------||----------|-|-||-------||-||-----|---|||||-- 0 [E] COG2986 Histidine ammonia-lyase ---|||--------------||----------|-|-||-------|--||-----|---|||||-- 0 [E] COG2987 Urocanate hydratase ------------------||------|-------|-------|||||-|--|-------------- 0 [G] COG3001 Fructosamine-3-kinase ----------------|-----------------|-|-----------|----------------- 0 [S] COG3002 Uncharacterized protein conserved in bacteria ------------------||--------------|-||-------|--||--|--|------||-- 0 [S] COG3011 Uncharacterized protein conserved in bacteria --------------------|---------------||----|||-|-||---------------- 0 [E] COG3048 D-serine dehydratase --|---------------|------------|--|-|---------|-|----------|-||--- 0 [M] COG3049 Penicillin V acylase and related amidases --------------------|-----|----------|----|--||-||||-------||--|-- 0 [G] COG3090 TRAP-type C4-dicarboxylate transport system, small permease component -----------------|------------|-----||----||||||||-----|---------- 0 [N] COG3144 Flagellar hook-length control protein ---------------------|----|---------|-----|||||--|--|------------- 0 [S] COG3162 Predicted membrane protein -------------------||-----|-------|-||----|||-|-||---------||-|--- 0 [R] COG3180 Putative ammonia monooxygenase --------------------|-----|---------||--------|-||-|---|---||----- 0 [S] COG3181 Uncharacterized protein conserved in bacteria --------------------------|-------|--|----------||---|||---|---|-- 0 [S] COG3182 Uncharacterized iron-regulated membrane protein ----||-----|--------------|||-----|-------|||-|--|-----|---||||--- 0 [S] COG3189 Uncharacterized conserved protein ----------------------||------------||----||||||||-----|---------- 0 [N] COG3190 Flagellar biogenesis protein ---------------------|----|---------||-----------|-----|---|||||-- 0 [S] COG3195 Uncharacterized protein conserved in bacteria -------------------|-------||||-----||-------|---|-----|---|--|--- 0 [Q] COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis -------------------|-----------------|----------||--------|||-||-- 0 [R] COG3211 Predicted phosphatase ---|------|--------||-----|||--|--|--|----||||--||---------||-||-- 0 [P] COG3221 ABC-type phosphate/phosphonate transport system, periplasmic component --|----------------|----------|---|-|-----------||---------------- 0 [E] COG3227 Zinc metalloprotease (elastase) ------------------||-------||-------|------------|-----|----|-||-- 0 [I] COG3239 Fatty acid desaturase -----------|-----|-------------|||---|----||||------|------||----- 0 [G] COG3250 Beta-galactosidase/beta-glucuronidase ---------------------------||-------|------|--|--|-----|---|------ 0 [S] COG3251 Uncharacterized protein conserved in bacteria ----||--|-|||---|--------------------|-----------|------------||-- 0 [I] COG3255 Putative sterol carrier protein --------------------|----------------|----|||-|-||---------|--|--- 0 [P] COG3263 NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain --------------------|-------------|-|-----|||||-|-----------|----- 0 [T] COG3275 Putative regulator of cell autolysis -------------------|----------|-----||----|-----||-----|---|||||-- 0 [QK] COG3284 Transcriptional activator of acetoin/glycerol metabolism ---------------------------||-------||-----------|---------||-|--- 0 [L] COG3285 Predicted eukaryotic-type DNA primase --------------------------|-----|---||----|||-|-|----------------- 0 [T] COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism |||---|-|---|------------------|-----|----------|----------------- 0 [R] COG3291 FOG: PKD repeat ------------------||-|------------|--------------|---------------- 0 [S] COG3296 Uncharacterized protein conserved in bacteria ------------------|-----------------|---------|--|-----|---||-||-- 0 [T] COG3300 MHYT domain (predicted integral membrane sensor domain) -----------------||||---------|--||-------|||||-||||||||||-||||||| 0 [M] COG3307 Lipid A core - O-antigen ligase and related enzymes --------------------|---------|---|-||----|||-|-|-----------|----- 0 [S] COG3314 Uncharacterized protein conserved in bacteria --|----------------||------|||------|-----------||-|--------|-|--- 0 [Q] COG3315 O-Methyltransferase involved in polyketide biosynthesis ----------------------||------------|-----|||-|-||---||----------- 0 [R] COG3318 Predicted metal-binding protein related to the C-terminal domain of SecA -------------------|------||||------|-----|||||--|-----|-----||--- 0 [Q] COG3319 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases -------------||----|-------|||----|--------------|---------|------ 0 [Q] COG3320 Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes -------------------|------|||||-----|--------|---------|---||-|--- 0 [Q] COG3321 Polyketide synthase modules and related proteins --|-----------------------|||--------|--------|-||-|---|---|||||-- 0 [R] COG3324 Predicted enzyme related to lactoylglutathione lyase -----------|---------------||--------|----|-----------------|----- 0 [K] COG3327 Phenylacetic acid-responsive transcriptional repressor --|-||-----|------|--------||-||-----||----||||--------|----|-|--- 0 [L] COG3328 Transposase and inactivated derivatives ------------------||-------||--------|-------------------------|-- 0 [R] COG3329 Predicted permease -----------------|||----------|------|---------------------------- 0 [S] COG3330 Uncharacterized protein conserved in bacteria -------------|-----------------------|-----------|-----|---------- 0 [S] COG3332 Uncharacterized conserved protein --------------------|-----|----------|--------|-||-|---|---||----- 0 [S] COG3333 Uncharacterized protein conserved in bacteria ----------------|-------------------||------------------||||||||-- 0 [S] COG3334 Uncharacterized conserved protein --|--|--|--|------||-|----|------|---|-----||-|-------||----|-|--- 0 [L] COG3335 Transposase and inactivated derivatives ---------------------|----||||------||----------------------|-|--- 0 [S] COG3336 Predicted membrane protein --------|-------|--------------------|---------------------------- 0 [L] COG3337 Uncharacterized protein predicted to be involved in DNA repair |-|---------------||----------|-----||-----------------|---|||||-- 0 [S] COG3339 Uncharacterized conserved protein -------------||--|------------|------|---------------------------- 0 [R] COG3341 Predicted double-stranded RNA/RNA-DNA hybrid binding protein ---|------|||------------------------|-----------|---------------- 0 [S] COG3342 Uncharacterized conserved protein --|----------|----|||------||-|---|--|----|--||-||----------|----- 0 [L] COG3344 Retron-type reverse transcriptase -----------------|---------------|---|-------|--|----------------- 0 [G] COG3345 Alpha-galactosidase ----|-------------|-----------------||-------|-------------||-|--- 0 [S] COG3347 Uncharacterized conserved protein |-||--------------------------|-----||---------------------------- 0 [L] COG3359 Predicted exonuclease ---|-----------------------||-------|----------------------------- 0 [S] COG3361 Uncharacterized conserved protein ----|------|--|------------||-----|----------||--------|||-------- 0 [P] COG3376 High-affinity nickel permease --|-||--|---------------------------||---------------------------- 0 [S] COG3377 Uncharacterized conserved protein ---------||||-----------------|||---||--------|--|-----|------|--- 0 [S] COG3382 Uncharacterized conserved protein --||-|-----|------||-|---------------|----|------------|----|----- 0 [L] COG3385 FOG: Transposase and inactivated derivatives ----||-----|-|-------|------------|-|---------|--|-||--|---|||||-- 0 [G] COG3386 Gluconolactonase --|-|------|-------|-|--||-||-|-----||----|||-|--|-----|----|-|--- 0 [S] COG3391 Uncharacterized conserved protein --------------------|----------------|------------------|||------- 0 [L] COG3392 Adenine-specific DNA methylase ------------------|||----------------|----|--||---||-------||||--- 0 [S] COG3395 Uncharacterized protein conserved in bacteria -----------|---------|---------------|----|------------|----|----- 0 [S] COG3396 Uncharacterized conserved protein ------------------------------------||------------------|||------- 0 [R] COG3401 Fibronectin type 3 domain-containing protein ---|-----------------|--------------|----------------------------- 0 [S] COG3403 Uncharacterized conserved protein ----------------|--------------------|----|||-|------------|------ 0 [G] COG3405 Endoglucanase Y --|-||||---|-|-----|-|---------------|----------------------|-|--- 0 [G] COG3408 Glycogen debranching enzyme --|---------------||-|----|||||-----||----------|------|---||||--- 0 [M] COG3409 Putative peptidoglycan-binding domain-containing protein ----|------|-|-----------------------|---------------------------- 0 [S] COG3410 Uncharacterized conserved protein ---|------------||||-|---------------|-----------------|---------- 0 [C] COG3411 Ferredoxin ---|----|--|-------|-|---------------|----------------------|-|--- 0 [L] COG3415 Transposase and inactivated derivatives ---------------------|-----||-------||---------------------------- 0 [Q] COG3424 Predicted naringenin-chalcone synthase ---------------------------||-------|-----|||||-||-----------|---- 0 [Q] COG3433 Aryl carrier domain ----------------|-------------------|-----------|----------------- 0 [T] COG3434 Predicted signal transduction protein containing EAL and modified HD-GYP domains -----------|--------------|----------|-----||-|--|-----|---------- 0 [Q] COG3435 Gentisate 1,2-dioxygenase ------------------||------|||||||||------------------------------- 0 [R] COG3442 Predicted glutamine amidotransferase -------------------------------||||-|-----|||-|------------|--|--- 0 [R] COG3443 Predicted periplasmic or secreted protein -----------------|----------------|--|----|---|---------------|--- 0 [E] COG3457 Predicted amino acid racemase -----------------|---------------|--||---------------------|--|--- 0 [Q] COG3458 Acetyl esterase (deacetylase) ---------------------|---------------|----|------------|----|----- 0 [Q] COG3460 Uncharacterized enzyme of phenylacetate metabolism --|--|-------------||-----|||----||--|-----------------|---||-|--- 0 [L] COG3464 Transposase and inactivated derivatives ----||--|---------------------------||---------------------------- 0 [S] COG3465 Uncharacterized conserved protein |-|||--------------|||--------||-----|--------|------|||----|||--- 0 [R] COG3467 Predicted flavin-nucleotide-binding protein --|-----|-----|---||----------||----|----------------------||----- 0 [T] COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) -------------------------------|--|-------||||------------|------- 0 [S] COG3477 Predicted periplasmic/secreted protein -||-----------------|----------|----|----------------------------- 0 [R] COG3478 Predicted nucleic-acid-binding protein containing a Zn-ribbon domain -------------------------------|----|-----------|----------------- 0 [Q] COG3479 Phenolic acid decarboxylase ---|----------|----|-----------------|-------|---|-----|----|-|--- 0 [Q] COG3486 Lysine/ornithine N-monooxygenase --------------------|----------||---||--------|-|----------------- 0 [C] COG3493 Na+/citrate symporter ------------------------------||----||----|-----------------|--|-- 0 [G] COG3507 Beta-xylosidase -----------------|-------------------|-----||-|------------||-||-- 0 [S] COG3533 Uncharacterized protein conserved in bacteria -----------------|------------|-----||---------------------||-||-- 0 [G] COG3534 Alpha-L-arabinofuranosidase -------------------|------|---------|------------|----------|-||-- 0 [P] COG3540 Phosphodiesterase/alkaline phosphatase D -|-----------------|----------|-----|------------|-----|------|--- 0 [R] COG3541 Predicted nucleotidyltransferase -------------|----|--------------||--------------------|---||-||-- 0 [S] COG3542 Uncharacterized conserved protein ---------------------|------------|-||-----------|-----|---|||||-- 0 [R] COG3545 Predicted esterase of the alpha/beta hydrolase fold ----------|--------|----------|-----||-----||-|--|---------------- 0 [P] COG3546 Mn-containing catalase --|--------|-------||-----||||--||---|-------|---|---||----||-||-- 0 [L] COG3547 Transposase and inactivated derivatives -------------------------------------|-----------|------------|--- 0 [S] COG3551 Uncharacterized protein conserved in bacteria --------------------------|||--|-----|---------------------------- 0 [M] COG3559 Putative exporter of polyketide antibiotics ------------------------------|||-|--------||-----|---|----------- 0 [K] COG3561 Phage anti-repressor protein ---------------------------||--------|----------------------|||--- 0 [S] COG3564 Uncharacterized protein conserved in bacteria ---------------|--|-|---------|---|-----------------|------||-|--- 0 [G] COG3588 Fructose-1,6-bisphosphate aldolase ---------------------------------||-|-----|||||-------------|-|--- 0 [E] COG3591 V8-like Glu-specific endopeptidase -------------------|----------------|-----------|---------------|| 0 [R] COG3621 Patatin --||-----------------|-----||-------|------------|---------|--||-- 0 [R] COG3631 Ketosteroid isomerase-related protein -------------------------------||-|-|-----|||-|--|--|--|-------|-- 0 [O] COG3634 Alkyl hydroperoxide reductase, large subunit ---|---------------||-----|----|--|--|-|--||||---|---------||-||-- 0 [P] COG3638 ABC-type phosphate/phosphonate transport system, ATPase component ---|------|--------||-----|----|--|--|-|||||||---|---------||-||-- 0 [P] COG3639 ABC-type phosphate/phosphonate transport system, permease component --------------|------|--------------||---------------------------- 0 [Q] COG3648 Uricase (urate oxidase) -----------------|--------------|----|---------------------------- 0 [L] COG3649 Uncharacterized protein predicted to be involved in DNA repair -----------------|-------------------|-------------------------|-- 0 [G] COG3661 Alpha-glucuronidase --------------|------|--------------|----------------------||--|-- 0 [S] COG3665 Uncharacterized conserved protein --|----------------||---------|-|||--|-----------|---------||--|-- 0 [L] COG3666 Transposase and inactivated derivatives ------||----------||------|||||||||----------------------------|-- 0 [K] COG3682 Predicted transcriptional regulator -----------------|-|----------|------|---------------------|---|-- 0 [G] COG3693 Beta-1,4-xylanase -------------||---------------------|-----|||----------|---|||||-- 0 [P] COG3703 Uncharacterized protein involved in cation transport -----------------|||-----|-----------|-----------|--------|||||||| 0 [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain ---------------------------||--------|----|||||-|-----------|-|--- 0 [K] COG3710 DNA-binding winged-HTH domains ------------------------------------||----|||||------------||--|-- 0 [G] COG3717 5-keto 4-deoxyuronate isomerase -------------------|----------------|-----|||-|--|-------------|-- 0 [R] COG3729 General stress protein ------------------------------------||----|||-|--------|---|---|-- 0 [S] COG3766 Predicted membrane protein ------------------------------|-----||---------------------|||||-- 0 [M] COG3773 Cell wall hydrolyses involved in spore germination ------------------------------------|------|||-----|---------||--- 0 [R] COG3822 ABC-type sugar transport system, auxiliary component -------------------------------------|---------------------||-||-- 0 [S] COG3828 Uncharacterized protein conserved in bacteria ------------------------------|-----||----|||||-|||--------------- 0 [KT] COG3835 Sugar diacid utilization regulator ---------------------|------------|-------|||||--|-|---|---||||--- 0 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase ------------------||----------|-----||---------------------------- 0 [S] COG3854 Uncharacterized protein conserved in bacteria ---------------------------||-|-----||---------------------------- 0 [S] COG3856 Uncharacterized conserved protein (small basic protein) ------------------------------|-----||--------------|------------- 0 [R] COG3858 Predicted glycosyl hydrolase -------------------|-|--------|------|---------------------------- 0 [S] COG3860 Uncharacterized protein conserved in bacteria -------------------|-|--------|-----|----------------------------- 0 [S] COG3861 Uncharacterized protein conserved in bacteria --------|---------------------|-----|----------------------------- 0 [S] COG3863 Uncharacterized distant relative of cell wall-associated hydrolases -----------------|------------|-----||---------------------------- 0 [G] COG3866 Pectate lyase -----------------|------------|-----||-------|-------------------- 0 [G] COG3867 Arabinogalactan endo-1,4-beta-galactosidase |-|---------------------------|-----||---------------------------- 0 [S] COG3874 Uncharacterized conserved protein ----------------------||------|-----||---------------------------- 0 [S] COG3876 Uncharacterized protein conserved in bacteria ---------------------------||-|-----||---------------------------- 0 [S] COG3879 Uncharacterized protein conserved in bacteria ---------------------|--------|-----||---------------------------- 0 [S] COG3881 Uncharacterized protein conserved in bacteria ------------------------------|------|--------------------|-|----- 0 [Q] COG3882 Predicted enzyme involved in methoxymalonyl-ACP biosynthesis --|-----------------|-----|---|---|-------------|-------||-------- 0 [L] COG3886 Predicted HKD family nuclease --|-----------------------|----------|---------------------|--|--- 0 [R] COG3910 Predicted ATPase ------------------------------|---|-|----------------------------- 0 [G] COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation --|---------------||----------|------|---------------------------- 0 [S] COG3937 Uncharacterized conserved protein ------------------------------|------|--------|------------------- 0 [R] COG3940 Predicted beta-xylosidase -------------------------------||||----------------------------|-- 0 [R] COG3942 Surface antigen --------------------------|---|--||-||---------------------------- 0 [M] COG3944 Capsular polysaccharide biosynthesis protein ---------------------|--------|------|---------------------------- 0 [T] COG3947 Response regulator containing CheY-like receiver and SARP domains ------||------------------|---|---|-||---------------------------- 0 [S] COG3949 Uncharacterized membrane protein ---------------------------||-||--|-|----------------------------- 0 [R] COG3953 SLT domain proteins ------------------------------|---|-||---------------------------- 0 [R] COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain --|----------||------------|||||--|-----------|------------------- 0 [GHR] COG3961 Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes -------------------------------------|-------|-------------||||--- 0 [I] COG3963 Phospholipid N-methyltransferase -------------------------------------|-------|--|----------||----- 0 [P] COG3965 Predicted Co/Zn/Cd cation transporters -------------------|----------||----|------------------|---||----- 0 [M] COG3967 Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) ---------------------|----|---|-----|----------------------------- 0 [R] COG3973 Superfamily I DNA and RNA helicases -|----------------------------|-----|-------------------|-|----|-- 0 [M] COG3980 Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase --------------------||----|---||||---|----------|--|----------|--- 0 [R] COG3981 Predicted acetyltransferase ------||-|---------------------------|---------------------------- 0 [S] COG4043 Uncharacterized conserved protein ||-------|--------------------------||---------------------------- 0 [R] COG4085 Predicted RNA-binding protein, contains TRAM domain |--------|--------------------|--|--||---------------------------- 0 [S] COG4086 Predicted secreted protein -----------------|----------------|-|----------------------------- 0 [R] COG4112 Predicted phosphoesterase (MutT family) -------------------------------------|----|||||-------------|----- 0 [R] COG4114 Uncharacterized Fe-S protein -------------------|-------||----||------------------------|-----| 0 [S] COG4115 Uncharacterized protein conserved in bacteria ------------------------------|-----|----------------------||||--- 0 [G] COG4124 Beta-mannanase -------------------------------------|----|||-----||-------------- 0 [R] COG4146 Predicted symporter --------|-------|--|-|----|---------||----|||||-||--|--|---------- 0 [R] COG4147 Predicted symporter ----------------------------------|-------|||||-||||-------||||--- 0 [P] COG4148 ABC-type molybdate transport system, ATPase component -|------|-|||----|||||----|------|---|----|||||--|-----|--|||||--- 0 [E] COG4177 ABC-type branched-chain amino acid transport system, permease component ---------------------|--------|-----|-----------------------|----- 0 [E] COG4187 Arginine degradation protein (predicted deacylase) ------------------||-----------------|-----------|-----|---|---|-- 0 [R] COG4188 Predicted dienelactone hydrolase -------------------------------------|---------------------||-|--- 0 [K] COG4189 Predicted transcriptional regulator ------------------------------|--||-|----------------------------- 0 [G] COG4193 Beta- N-acetylglucosaminidase ---------------------------||-------|-------------------------|--- 0 [R] COG4195 Phage-related replication protein ------------------------------|------|-------------------------|-- 0 [S] COG4200 Uncharacterized protein conserved in bacteria ------------------||-------||--------|----|||||-||--||||---|||||-- 0 [P] COG4208 ABC-type sulfate transport system, permease component -------------------------------------|-|--||||----|----|---||||--- 0 [G] COG4213 ABC-type xylose transport system, periplasmic component -------------------------------------|-|--||||----|----|---||||--- 0 [G] COG4214 ABC-type xylose transport system, permease component ------------------------------|---|----------------------------|-- 0 [KT] COG4219 Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component ------------------------------|-----||-------||------------|------ 0 [R] COG4225 Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins ------------------||----------|---|-||---------------------------- 0 [S] COG4241 Predicted membrane protein -------------------|----------------|--------------------------|-- 0 [I] COG4247 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) -------------------------------|----||-----------------|---------- 0 [S] COG4260 Putative virion core protein (lumpy skin disease virus) ---|---------------|--------------|--|-------|---------|----|----- 0 [Q] COG4264 Siderophore synthetase component -------------------|-|------------|--------------|---------------- 0 [S] COG4270 Predicted membrane protein ---|---------------|------|----------|---------------------------- 0 [S] COG4276 Uncharacterized conserved protein -------------|||------||-|--------|------------------------------- 0 [G] COG4284 UDP-glucose pyrophosphorylase --------------|----|-|--------------||---------------------------- 0 [L] COG4294 UV damage repair endonuclease ---------------------|--------------|----------------------||----- 0 [S] COG4297 Uncharacterized protein containing double-stranded beta helix domain -------------------|------|----||||------------------||----------- 0 [P] COG4300 Predicted permease, cadmium resistance protein ------------------------------------|---------------|--|---------- 0 [G] COG4305 Endoglucanase C-terminal domain/subunit and related proteins -------------------------------------|-----------|-----|---||----- 0 [S] COG4317 Uncharacterized protein conserved in bacteria -------------------|----------------|------------|-----|----|-|--- 0 [S] COG4319 Ketosteroid isomerase homolog -------------------|----------------|-----------|----------------- 0 [R] COG4326 Sporulation control protein -------------------|-----------------|----------|------|---------- 0 [S] COG4327 Predicted membrane protein -------------------|-----------------|----------------------|----- 0 [S] COG4329 Predicted membrane protein ----------------------------------|--------||---------------|----- 0 [S] COG4333 Uncharacterized protein conserved in bacteria ------------------------------------|--------------|-------|------ 0 [L] COG4335 DNA alkylation repair enzyme --------------|-----------|---------|------------|---------|------ 0 [S] COG4336 Uncharacterized conserved protein -------------||-----------------|||------------------------------- 0 [S] COG4357 Uncharacterized conserved protein -------------||---------------|-----|----------------------------- 0 [E] COG4359 Uncharacterized conserved protein, possibly involved in methylthioadenosine recycling ---------------------|------------|-||---------------------------- 0 [PE] COG4362 Nitric oxide synthase, oxygenase domain ---------------------|------------|-||---------------------------- 0 [S] COG4365 Uncharacterized protein conserved in bacteria ---------------------------------|--|------------------|---------- 0 [S] COG4377 Predicted membrane protein ------------------------------|------|--------------------|------- 0 [S] COG4378 Uncharacterized protein conserved in bacteria -------------------|----------|-||---|---------------------------- 0 [V] COG4403 Lantibiotic modifying enzyme ----------------------------------|--|-------|---|---------------- 0 [S] COG4408 Uncharacterized protein conserved in bacteria ------------------------------|-----|-----------|----------------- 0 [S] COG4412 Uncharacterized protein conserved in bacteria ----------------------------------|----------|---|-----------|---- 0 [E] COG4413 Urea transporter -------------------------------------|-------------------------|-| 0 [G] COG4421 Capsular polysaccharide biosynthesis protein ------------------------------|--||-||---------------------------- 0 [GM] COG4464 Capsular polysaccharide biosynthesis protein --------------------|---------||-|--||---------------------------- 0 [G] COG4468 Galactose-1-phosphate uridyltransferase -------------------------------||||-||---------------------------- 0 [S] COG4475 Uncharacterized protein conserved in bacteria -------------------------------||||-|----------------------------- 0 [S] COG4485 Predicted membrane protein --------------------|---------|---|-||---------------------------- 0 [R] COG4492 ACT domain-containing protein ------------------------------||--|--|---------------------------- 0 [S] COG4495 Uncharacterized protein conserved in bacteria ------------------------------|---|-|----------------------------- 0 [S] COG4502 Uncharacterized protein conserved in bacteria ------------------------------|------|-|-------------------------- 0 [S] COG4508 Uncharacterized protein conserved in bacteria --------------------------|||-----|-------|||--------------||||--- 0 [S] COG4529 Uncharacterized protein conserved in bacteria ----------------------------------|-------|||||-||||---|----|||||| 0 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB ----------------------------------|-|------------|---------|||---- 0 [P] COG4548 Nitric oxide reductase activation protein -------------------||------||--|-----|---------------------------- 0 [R] COG4552 Predicted acetyltransferase involved in intracellular survival and related acetyltransferases -----------------|---|--|-----|-----|---------------|------------- 0 [CP] COG4555 ABC-type Na+ transport system, ATPase component --------------------------|-----|---||----|||-|-|----------------- 0 [KT] COG4565 Response regulator of citrate/malate metabolism --------------------------||||-------|----|||-|----|----------|--- 0 [K] COG4578 Glucitol operon activator ----------------------------------|-|-----|--------|-------------- 0 [P] COG4594 ABC-type Fe3+-citrate transport system, periplasmic component --------------------------|------||-||-------|--|----||---||-|---- 0 [P] COG4604 ABC-type enterochelin transport system, ATPase component --------------------------|------||-||-------|--|----||---||-|---- 0 [P] COG4605 ABC-type enterochelin transport system, permease component --------------------------|------||-||-------|--|----||---||-|---- 0 [P] COG4606 ABC-type enterochelin transport system, permease component --------------------------|------||-||-------|--|----||---||-|---- 0 [P] COG4607 ABC-type enterochelin transport system, periplasmic component ----------------------------------|-------|||-|--------|---------- 0 [R] COG4619 ABC-type uncharacterized transport system, ATPase component ------------------||-|---------------|---------------------------- 0 [S] COG4627 Uncharacterized protein conserved in bacteria ------------------------------||----|----------------------------- 0 [G] COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase ------------------------------|---|-|----------------------------- 0 [S] COG4640 Predicted membrane protein ------------------------------|-----||----------------------|----- 0 [S] COG4641 Uncharacterized protein conserved in bacteria -------------------------------|-||--|---------------------------- 0 [S] COG4652 Uncharacterized protein conserved in bacteria ---|----|---|--------|---------------|----------||-|--------||---- 0 [R] COG4666 TRAP-type uncharacterized transport system, fused permease components ------------------||-|----|----------|-------|---|-----|---||-|--- 0 [R] COG4674 Uncharacterized ABC-type transport system, ATPase component ------------------------------------|-----|||||--------|---------- 0 [S] COG4682 Predicted membrane protein -------------------------------|--|--|---------------------------- 0 [S] COG4707 Uncharacterized protein conserved in bacteria ------||----------------------|||||------------------------------- 0 [S] COG4720 Predicted membrane protein --------------------------|------||-|----------------------------- 0 [S] COG4721 Predicted membrane protein -------------------------------|-|---|---------------------------- 0 [G] COG4724 Endo-beta-N-acetylglucosaminidase D ---|----|----------------------------|-----------|-|-------------- 0 [S] COG4729 Uncharacterized conserved protein ----------|-|--------------------||------------------------------- 0 [S] COG4732 Predicted membrane protein ---|--|||--|-||--|--||----||||------||-----------|-----|---||||||| 0 [I] COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) --------------------------||||-------|---------------------------- 0 [S] COG4825 Uncharacterized membrane-anchored protein conserved in bacteria --------------------|---------------|-----------------------|-|--- 0 [R] COG4857 Predicted kinase --|-----------------------|------|--|----------------------------- 0 [S] COG4894 Uncharacterized conserved protein --|------------------|--------------|----------------------------- 0 [S] COG4895 Uncharacterized conserved protein --------------------|-------------|-------------------------|----- 0 [R] COG4927 Predicted choloylglycine hydrolase |-|-------|--------|------|---|-----||---------------------------- 0 [KT] COG4978 Transcriptional regulator, effector-binding domain/component ------------------------------|-----|----------------------||||--- 0 [S] COG4991 Uncharacterized protein with a bacterial SH3 domain homologue ----------|-|-------------|||-----|-|-----|||-|--|-----|-----|---- 0 [C] COG5013 Nitrate reductase alpha subunit --------------|---------------------|------------|---------------- 0 [R] COG5018 Inhibitor of the KinA pathway to sporulation, predicted exonuclease --------------|----|----------------|----------------------------- 0 [GM] COG5039 Exopolysaccharide biosynthesis protein -------------||-------------------|------------------------------- 0 [H] COG5146 Pantothenate kinase, acetyl-CoA regulated -------------------|-|---------------|-----------------|---|--||-- 0 [T] COG5278 Predicted periplasmic ligand-binding sensor domain -------------------|----------------|---------------|------------- 0 [S] COG5293 Uncharacterized protein conserved in bacteria --|-----------------|----------------|-----||||---||||||----|||--- 0 [UW] COG5295 Autotransporter adhesin --|-----------------------|---------|----------------------------- 0 [M] COG5337 Spore coat assembly protein ------------------||----||----------||---------------------------- 0 [R] COG5401 Spore germination protein ------|-|-|-------|-------|---------|----------------------------- 0 [S] COG5428 Uncharacterized conserved small protein --------------------|-----|---||--|------------------------------- 0 [S] COG5438 Predicted multitransmembrane protein -------------------------------------|-------|-------------|---|-- 0 [S] COG5460 Uncharacterized conserved protein -------------||----------------------|---------------------------- 0 [M] COG5498 Predicted glycosyl hydrolase ---------------------|------------|-||---------------------------- 0 [O] COG5504 Predicted Zn-dependent protease -------|------------|---------------||---------------------------- 0 [S] COG5505 Predicted integral membrane protein --|-------------------------------|--------||||----|-------------- 0 [L] COG5519 Superfamily II helicase and inactivated derivatives ------------------------------|-----|---------|----------------|-- 0 [M] COG5520 O-Glycosyl hydrolase --------------------|---|-|---------|----------------------------- 0 [S] COG5522 Predicted integral membrane protein -------------------------------||||------------------------------- 0 [S] COG5547 Small integral membrane protein ------------------------------|---|-||---------------------------- 0 [M] COG5577 Spore coat protein -----------------|------------|-----||----|||||--|---------------- 0 [M] COG5581 Predicted glycosyltransferase ------------------------------|-----||-----------|---------------- 0 [S] COG5583 Uncharacterized small protein --|---------------------------|-|----|---------------------------- 0 [T] COG5585 NAD+--asparagine ADP-ribosyltransferase -------------------|--------------|-||---------------------------- 0 [S] COG5609 Uncharacterized conserved protein -------------------------------------|-------------------------|-| 0 [R] COG5628 Predicted acetyltransferase -------------------|----------------|------------------|---------- 0 [S] COG5634 Uncharacterized conserved protein ------------------------|-||||------|----------------------------- 0 [S] COG5660 Predicted integral membrane protein ------------------||----|--||-------||-----------------|---||-|--- 0 [K] COG5662 Predicted transmembrane transcriptional regulator (anti-sigma factor) ------------------------------|-----||------------------------|--- 0 [S] COG5663 Uncharacterized conserved protein