(Lin) Listeria innocua
Functional categories
Fun All J A K L B D Y V T M N Z W U O C G E F H I P Q R S
COGs 1,522 134 86 102 19 16 53 67 35 35 49 70 103 152 61 88 42 79 22 187 238
proteins 2,529 152 271 168 31 75 136 113 45 48 65 119 291 245 74 107 58 155 47 363 301
Distribution of COGs by number of proteins
proteins 123456789101112131415192123
COGs 110921488422112782723111211
Co-ocurrences in sister taxa0123
order Bacillales 105154285978
++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
||||||||||||||||||||||||||||||||||||||-||||||||||||||||||||||||||| 23 [GEPR] COG0477 Permeases of the major facilitator superfamily
|-|-------|-----||-|||--|-|||-||||||||----|||||-||||||||---||||||| 21 [K] COG1396 Predicted transcriptional regulators
|||||||||-||||||||||||||--|||||||||||||---|||||-||||||||||||||||-| 19 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
--------------------|-|||||---||||||||-||||||||-||||-|||---|||||-- 19 [GT] COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)
|-||||||||||||||-|||-|---||||||||||||||||-|||||-||-|||||||-|||||-- 15 [V] COG1131 ABC-type multidrug transport system, ATPase component
|||||||||||||----|-|||----||||||||||||----|||||-||--||||---|||||-- 14 [K] COG1846 Transcriptional regulators
-------------||||||||||||-|||||||-||||----|||||-||||||||--||||||-- 13 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
|-||||||||||||||-||||||||||||||||||||||||||||||||-||-|||---||-|--- 12 [R] COG0561 Predicted hydrolases of the HAD superfamily
|-||---||--|----||||||----|||||||||||||---|||||-||||||||--||||||-- 12 [K] COG1309 Transcriptional regulator
--------------------|-----|---||||||||----|||||------------------- 12 [K] COG3711 Transcriptional antiterminator
--||--||--||-|||||||||||--|||||||||||||||||||||||||||||||||||||||| 11 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components
||||----|||||---|||||||||||||-|||||||||||||||||||||||||||||||||||| 11 [V] COG1136 ABC-type antimicrobial peptide transport system, ATPase component
----------------||||||||--||||||||||||----|||||-|||||||||||||||||| 10 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
--|-----|-------|-||||----||||||||||||----|||||-|||||||||||||||||| 10 [K] COG0789 Predicted transcriptional regulators
-------------------------|----||||-|||----|||||-|----------------- 10 [G] COG1440 Phosphotransferase system cellobiose-specific component IIB
-------------------------|----||||||||----|||||-|----------------- 10 [G] COG1455 Phosphotransferase system cellobiose-specific component IIC
-----------------|--||----|||-||||||||-|--|||||-|||||--|---|||||-- 10 [K] COG1609 Transcriptional regulators
-|-|----|-------|---------|-------||---------|------|--------|||-- 10 [L] COG3316 Transposase and inactivated derivatives
--|----------|||---|----------|-|--|------|||||--|-----|---------- 10 [S] COG4886 Leucine-rich repeat (LRR) protein
|||||||||--||---||||||||--||||||||||||||--|||||-||||||||||||||||||  9 [L] COG0582 Integrase
----||||--||--------------|---||||||||----|||||-|----------||--|--  9 [G] COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase
|-||--|||--||||---||||----||||||||||||----|||||-||||||||--||||||--  8 [E] COG0346 Lactoylglutathione lyase and related lyases
||||----||||-----||||||||-|||-||||||||----|||||-||-|-|||--||||||--  8 [V] COG0577 ABC-type antimicrobial peptide transport system, permease component
||------||------|-||||----||||||||||||----|||||-||||||||--||||||--  8 [K] COG0583 Transcriptional regulator
|-||||||-|||-||-||||-|----|---||||||||----|||||-||-|---|||||||||--  8 [R] COG0673 Predicted dehydrogenases and related proteins
--|||||||-||||||||||||||--||||||||||||----||||||||||||||||||||||||  8 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
-------------------------|----||||||||----|||||-|-----------------  8 [G] COG1447 Phosphotransferase system cellobiose-specific component IIA
---|||--|-|-|---||||||---|||||||||||||-|--|||||-|-||-------|||||--  8 [KG] COG1940 Transcriptional regulator/sugar kinase
-------------------|-|----|||-||||||||||--|||||-||-----|---|||||--  8 [K] COG2188 Transcriptional regulators
--|-||-----|-||-||||||----||||||||||||----|||||-||-||--|---|||||--  7 [G] COG0406 Fructose-2,6-bisphosphatase
|||||||||||||||||||||||||-||||||||||||----||||||||||||||||||||||||  7 [QR] COG0500 SAM-dependent methyltransferases
|-||----|----||-||||||||-|||||||||||||----|||||-||||||||||||||||||  7 [T] COG0642 Signal transduction histidine kinase
-----------------||||||||--||-|---||||----------||---------||--|--  7 [T] COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
----------------|----|||-||||-||--||||-------|--||||--------------  7 [M] COG1388 FOG: LysM repeat
-----------------||||-----|||-||-|||||----|||||-||||||||--||||||--  7 [K] COG2207 AraC-type DNA-binding domain-containing proteins
------------------|||--------------|------|||-|-------------------  7 [QC] COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein
---|||||--|||----|||-|--|-||||||||-|||-||||||||-||-||--|---||||---  6 [G] COG0395 ABC-type sugar transport system, permease component
|||||||||--|-|||||||||||||----||||||||----|||||-||-|||||||||||||||  6 [R] COG0457 FOG: TPR repeat
|-||||--|-|||||||||||||||-||||||||||||----||||||||||||||||||||||||  6 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
|||||||||-||||||||||||||||||||||||||||||||||||||||||||||||||||||||  6 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins
||||--|||---|||-|||-||--|||||-|||||||||||||||||-||||||||||||||||--  6 [V] COG0534 Na+-driven multidrug efflux pump
----------------||||||||||||||||||||||----||||||||||||||||||||||||  6 [D] COG0772 Bacterial cell division membrane protein
---|||||--|||----|||-|--|-||||||||||||-||||||||-||-||--|---||||---  6 [G] COG1175 ABC-type sugar transport systems, permease components
----------------||--||----|---||||||||----|||||-||||-|||---||||---  6 [KG] COG1349 Transcriptional regulators of sugar metabolism
---|||||--|||----|||-|--|-||||||||-|||----|||||-||-||--|---||||---  6 [G] COG1653 ABC-type sugar transport system, periplasmic component
-|||||-|-----||--|-|||----||||||||||||--|-|||||-||-|-|||||||||||||  6 [J] COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
-----------------|-------------||-|||-----|||||-||-----|-----|----  6 [NU] COG1705 Muramidase (flagellum-specific)
----------------------------------|||-----------------------------  6 [M] COG5632 N-acetylmuramoyl-L-alanine amidase
-|--||-------||||||||||||-||||||||||||||||||||||||||||||||||||||--  5 [G] COG0036 Pentose-5-phosphate-3-epimerase
--|-||----|--||--|||-|----|||-||||||||-|--|||||-||-----|---||-||--  5 [G] COG0366 Glycosidases
||||||||||||||||||||||---||||||||||||||||||||||-||||||||||||||||||  5 [M] COG0463 Glycosyltransferases involved in cell wall biogenesis
-------------|||--||||||||||||||||||||-|--||||||||||||||||||||||||  5 [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains
|||||||||||||||-||||||||-|||||||||||||----|||||-||||||||||||||||||  5 [R] COG0517 FOG: CBS domain
--||||--|-|||||||-||||---|||||||-||||||||||||||-||||||||||||||||||  5 [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) 
-||||||||-|||----|||||----||||||||||||----|||||-||||---|||||||||--  5 [P] COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component
|||||||||||||---||||||----|||||||-||||----|||||-||-|||||--||||||--  5 [K] COG0640 Predicted transcriptional regulators
--|-----|-|-|----|||||||--|---||||||||----|||||-|||--|||||||||||||  5 [E] COG0765 ABC-type amino acid transport system, permease component
|||||--||||||---||||||----||||||||||||----|||||-||||||||||||||||--  5 [C] COG0778 Nitroreductase
------------------||-|||--||||||---|||----|||||-||||||||||||||||--  5 [M] COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
||||||---||||||-|-||||----|||||||||||||---|||||-||-|-|||||||||||-|  5 [C] COG1012 NAD-dependent aldehyde dehydrogenases
--|||||||--||||--|-|-|-----||-||||||||--|-|||||-|||-||||---||-||--  5 [ER] COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
---------|-------|--|-||-|----||||||||||||------|----------|||----  5 [S] COG1284 Uncharacterized conserved protein
--------------------||---||---||||||||-||||||||-|||----|----------  5 [G] COG1299 Phosphotransferase system, fructose-specific IIC component
||-|--|||-|||---|--|-|||||||||||||||||----|||||-||--||||||||||||||  5 [K] COG1475 Predicted transcriptional regulators
|-|||||||-|||----|-|||----||||||||||||----|||||-|------|------||--  5 [K] COG1695 Predicted transcriptional regulators
----|------|-----|--||----|||-|||-||||----|||||-||---|||---|||||--  5 [K] COG1802 Transcriptional regulators
-----||---|-------||-|----|||-|-||||||----|||||-||--|--|---|||||--  5 [L] COG1961 Site-specific recombinases, DNA invertase Pin homologs
-----------------------------------||-----|||||-||||--------------  5 [T] COG3103 SH3 domain protein
-------------------------------|---|-|----------------------------  5 [M] COG4932 Predicted outer membrane protein
||||||--|||||||-||||||||-|||||||||||||-||||||||-|-|||--|--||||||||  4 [C] COG0039 Malate/lactate dehydrogenases
-|--||-------||-||||-|||--|||||-||||||----||||||||||-|||||||||||--  4 [G] COG0176 Transaldolase
-------------||-||||-|--||||||||||||||||||||||||||||-||||||-||||--  4 [G] COG0191 Fructose/tagatose bisphosphate aldolase
-------------|||-||||-||||||||||||||||-|--|||||-||||||||||-|||||--  4 [G] COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase
-----||----|-||--|||-------||--|||-|-|----|-----------------------  4 [G] COG0383 Alpha-mannosidase
|||||||||||||||-|||||||||-||||||||||||----|||||-||||||||||||||||||  4 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase
|||||||||||||||-||||||--|||||-||||||-|-||||||||-||-|---|---|||||--  4 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases
|||-||--|--|-||||-||||--|-||||||||||||||||||||||||||||||||-|||||||  4 [LKJ] COG0513 Superfamily II DNA and RNA helicases
||-|||||-|--|||-||||||-|-|||||||||||||----||||||||||||||||||||||--  4 [F] COG0516 IMP dehydrogenase/GMP reductase
||||||--||||||||--|||-||--|||||||||||||||||||||-|||||--|---|||||||  4 [E] COG0531 Amino acid transporters
-||||||||-|||----|||||----|---|||||||||---|||||-||||---|||||||||--  4 [P] COG0609 ABC-type Fe3+-siderophore transport system, permease component
||||--|||-------||||||--|||||-||||||||----||||||||||||||||||||||||  4 [R] COG0628 Predicted permease
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  4 [L] COG0629 Single-stranded DNA-binding protein
---|||||--||||||-||-------||||||||||||----|||||--|-----|---|||||--  4 [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase
----------------|||-|-----|||||-|||||||||||--||----|----|||-|||-||  4 [G] COG0698 Ribose 5-phosphate isomerase RpiB
--|-----|-|-|----||||||||-||||||||||||----|||||-||||-|||||||||||||  4 [ET] COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain
|-||||||||||||||-|||-|----||||||||||||----|||||-||-||--|||-|||||--  4 [V] COG0842 ABC-type multidrug transport system, permease component
|||---||||-|-----|||------|||||-|-||||----|||||--|-----|---|||||--  4 [G] COG1082 Sugar phosphate isomerases/epimerases
|||||||||||||||||||||||||||||||||||||||-||||||||||||||||||||||||||  4 [G] COG1109 Phosphomannomutase
--|-----|-|-|----|||||||--|---||||||||----|||||-|||--|||||||||||||  4 [E] COG1126 ABC-type polar amino acid transport system, ATPase component
||||||--|||||||-||||||||--||||-|||||||-|||||||||||||||||---|||||||  4 [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
--------------------||---||---||||||||-||||||||-||||---|----------  4 [G] COG1445 Phosphotransferase system fructose-specific component IIB
--||||||---|-----|||||----|||-||-|||||----|||----|||---|--||||||--  4 [R] COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase
--|-------------|----------||-|||||||||---||||||-------|---||-|---  4 [L] COG1484 DNA replication protein
----||----||-||--|-|----------||-|-|-|----|||||--------|---|---|--  4 [G] COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases
----|------|-----|||------|||-|-||||||----------------------------  4 [K] COG1725 Predicted transcriptional regulators
-----------------|--------|---||||||||-|--|||||-||||-|||---|||||--  4 [K] COG1737 Transcriptional regulators
----------------||||||-----||-||-|||||----|||||-||||||||--||||||||  4 [K] COG1959 Predicted transcriptional regulator
----------------||||-|--|-|||||---||||----|||||-||--|--|---|||||--  4 [T] COG2199 FOG: GGDEF domain
|-||||-||-|||||-|||||||||-|||||||||||||---|||||-||||-|||||||||||--  4 [P] COG2217 Cation transport ATPase
-------------||-----||---------|--||-|----||||-----|-------||||---  4 [G] COG2376 Dihydroxyacetone kinase
--------------------||----|||||---||||----|---|-||--|-||--||||||--  4 [K] COG2378 Predicted transcriptional regulator
-------------------|------|||-||--||-|----|||-|--|-----|----|-||--  4 [S] COG2764 Uncharacterized protein conserved in bacteria
--------------------|---------||||-||-----|||||----|||||---|||||--  4 [G] COG2893 Phosphotransferase system, mannose/fructose-specific component IIA
-----|--------------||----|||--|||||-|----|||||-|||----|---|||||--  4 [L] COG2963 Transposase and inactivated derivatives
--------------------------|---|-||||-|-||-|||-|-|--|--------------  4 [G] COG3414 Phosphotransferase system, galactitol-specific IIB component
--------------------|---------||||-||-----|||||----|--------------  4 [G] COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB
-------------------------------||-|||------|||--------------------  4 [S] COG3645 Uncharacterized phage-encoded protein
--------------------|---------||||-||-----|||||----|--------------  4 [G] COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC
--------------------|---------||||-||-----|||||----|--------------  4 [G] COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID
-----------------|--|-|||||||-||-||||-||--|||||-||||---|||-||||---  4 [E] COG4166 ABC-type oligopeptide transport system, periplasmic component
--------------------------|---||-|-|-|----------------------------  4 [V] COG4767 Glycopeptide antibiotics resistance protein
-------------|||||||-||||-||||||||||||||||||||||||||||||||||||||--  3 [G] COG0021 Transketolase
|||-||-||||||||-||||-|----||||||-|||||----||||||||||||||--||||||--  3 [EH] COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]
||||---||||||||-||||||---||||-||||||||----|||||-||-|---|--||||||||  3 [P] COG0053 Predicted Co/Zn/Cd cation transporters
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  3 [R] COG0073 EMAP domain
---|||||---||||-||||--||--|----|||||||-||||||||-||----------------  3 [H] COG0095 Lipoate-protein ligase A
||||---|-||--||--|||-|||--||||||||||||----|||-|-||-|-|||--||||||-|  3 [R] COG0110 Acetyltransferase (isoleucine patch superfamily)
||||----|||--||-||||||----||||||||||||----|||||-||||||||||||||||||  3 [EH] COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase
||||||||||||||||||||||||||||||||||||||----||||||||||||||||||||||||  3 [H] COG0142 Geranylgeranyl pyrophosphate synthase
||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||--  3 [E] COG0169 Shikimate 5-dehydrogenase
|-||------------|||||||||||||||||||||||||||||||-||||||||||||||||||  3 [L] COG0178 Excinuclease ATPase subunit
||||---||----------|-------||--|||||--|||-|||-|-|||||||||||-||-|-|  3 [V] COG0286 Type I restriction-modification system methyltransferase subunit
--|----|---|-|||---||-----||||||||||||-----------|-|---|---||-||--  3 [R] COG0300 Short-chain dehydrogenases of various substrate specificities
||||||||||||||--||-||-|||-||||||-|||||-|--|||||-||||||||||||||||-|  3 [L] COG0350 Methylated DNA-protein cysteine methyltransferase
--||-------|-||---|||-----|||-|||||||||||||||||-||-|-|||---|||||--  3 [L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair
|-||----|----||-|-||-|----|||-||||||||----|||-|-||-|||||--||||||--  3 [T] COG0394 Protein-tyrosine-phosphatase
||||||||-||||||||||||||||-||||||||||||----||||||||||||||||||||||--  3 [M] COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains
||||||||||||||||||||||----|||||||||||||---|||||-||||||||--||||||--  3 [R] COG0456 Acetyltransferases
||----||-|||-||-||||||||||||||||||||||----|||||||||||||||||||||-||  3 [M] COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase
|||-|--------||||-|||-----||||||||-||||||||||||--|----------|||---  3 [P] COG0474 Cation transport ATPase
||||||||||||||||||||||----||||||||||||----||||||||||||||||||||||--  3 [R] COG0491 Zn-dependent hydrolases, including glyoxylases
||||||||||||||-|||||||||||||||||||||||||||||||||||||||||||||||||||  3 [O] COG0492 Thioredoxin reductase
||||--||-||||||--|||||--|||||-||||||||||||||||||||||-||||||||||---  3 [F] COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins
|||||-|||||||||-||||-|||--||||||-|||||----||||||||||||||||||||||||  3 [E] COG0527 Aspartokinases
|------------||||||||||||||||||||||||||-|||||||-||||||||||||||||||  3 [O] COG0542 ATPases with chaperone activity, ATP-binding subunit
--||-||||--|||||-|||||||--|||-||||-|||--|||||||-|||||-------|-----  3 [KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family
--||--|||----|||||||||||||||||||||||||||||||||||||||||||||||||||||  3 [F] COG0563 Adenylate kinase and related kinases
-------------|||||||||||||||||||||||||||||||||||||||||||||||||||||  3 [J] COG0564 Pseudouridylate synthases, 23S RNA-specific
----||-----|------||-|--||||||||--||||----|||||||||||||||||--|||--  3 [S] COG0586 Uncharacterized membrane-associated protein
|||||||||||||-|-|-||-|----||||-|||||||----|||||-||||-|||---|||||||  3 [T] COG0589 Universal stress protein UspA and related nucleotide-binding proteins
-||---|-|-||-||-||||||----|||||||||||-----|||||-|||||--|||||||||-|  3 [P] COG0598 Mg2+ and Co2+ transporters
--|||||||-|||---||||||||-||||||||||||||||||||||-||||---||||||||---  3 [EP] COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components
--||||----||-||-|--|-|----||||-|--||||----|||||-||-||--|---|||||--  3 [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases
|-||||--|-||-||||-||||---|||||||||||||----|||||||||||||||||||-||||  3 [P] COG0607 Rhodanese-related sulfurtransferase
||||--||||-||----|||||----||||||||||||||||-||-|---|--------|||----  3 [P] COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters
-|--|||||||||||-||--||-|--||||||||||||----||||||||||||||||||||||||  3 [E] COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases
--|-|||---||-||--|||-|||--|||||||-||||-|--|||||-||||||||---|||||--  3 [R] COG0637 Predicted phosphatase/phosphohexomutase
||||||||||||||||||||||||||||||||||||||-|--||||||||||||||||||||||||  3 [U] COG0681 Signal peptidase I
--|-||--|-|||---||||||---||||||||-||||--|||||||-||||||||||||||||--  3 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins
----------------||||||||||||||||||||||----||||||||||||||||||||||||  3 [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2
|-||--|||-|-|---|||||||||-||||||||||||-------||--|||-||---|||-|-||  3 [P] COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin
----------------|-|||||||||||||---||||----||||||||||||||||||||||--  3 [M] COG0860 N-acetylmuramoyl-L-alanine amidase
--||---||---||||-|-|||||--|||-|||--|||----|||||-||-||--|---|||||--  3 [R] COG1073 Hydrolases of the alpha/beta superfamily
|---||--||------||-||-||||----|----|||----|||||-|||||--||||----|||  3 [D] COG1077 Actin-like ATPase involved in cell morphogenesis
--|-----|----||||||||||||-||||||||||||----||||||||||-|||||||||||||  3 [E] COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes
|-||--|||-|-|---|||||||||-||-|||||||||----||||||||||-||---|||||-||  3 [P] COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components
-||||||||--||----|||||----|---|-|||||||-|||||||-||||---|||||||||--  3 [PH] COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components
|-||--|||-|||---|||||||||-|--|||||||||----||||||||||-||---|||||-||  3 [P] COG1121 ABC-type Mn/Zn transport systems, ATPase component
||||--|||||||----|||||--|-||||||||||||||||-||-|-|-|----|---|||----  3 [P] COG1122 ABC-type cobalt transport system, ATPase component
--|||||||-|||---||||||||-||||||||||||||||||||||-||||---||-|||||---  3 [EP] COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components
--------|----------|||-----||-|||||||-----|||||--|-----|||-||||---  3 [E] COG1174 ABC-type proline/glycine betaine transport systems, permease component
||||||||||----|-|-|||-||||----||||||||----||||---|-----|---|||||||  3 [R] COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
--||---------||-|||||||||||||-|||||||-||||||||||||||||||||||||||||  3 [R] COG1253 Hemolysins and related proteins containing CBS domains
|-||--||--|-|---|||||||||||||-||||||||-----||||-||-----|------||--  3 [R] COG1266 Predicted metal-dependent membrane protease
--|||||||--||----|||-|--||----|---|||||||--------|-----|----||----  3 [R] COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
---|------------||--||----|||||||-||||----||||||||||||||---|||||||  3 [K] COG1278 Cold shock proteins
-----------------|--||----|||-||||||||||||-------|----------------  3 [S] COG1307 Uncharacterized protein conserved in bacteria
-----------------|||-|--||||||||||||||----------------------------  3 [K] COG1316 Transcriptional regulator
--||--------------|-||----|||-||-|-||-----|||||-||-|-|||---||-||--  3 [S] COG1359 Uncharacterized conserved protein
||||--|||||-|----|-|||--------||||||||||--|||-|--|----------|-----  3 [G] COG1363 Cellulase M and related proteins
|-|||||||--||||-||--|-----|---||-|||||----|||||-||-|---|---||||---  3 [C] COG1454 Alcohol dehydrogenase, class IV
-----------------|------------|----|||----|||||-|----------||-|---  3 [G] COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
|--------------------|----||||||||||||----------------------------  3 [S] COG1511 Predicted membrane protein
-----------------|||||--|-||||||--||||----|||||-||||||||---|||||--  3 [K] COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
----|--------||--|||-|----|||-||||||||----|||||--|---------||-||--  3 [IR] COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
-----------------|------|---------||||----------------------------  3 [R] COG1647 Esterase/lipase
-------------------|-||||||||||||||||||---|||||-||||||||||||||||||  3 [D] COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins
--|---||--|-|-----||-|----||||||||||||----|||||--|--|--|---|||||||  3 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins
--|---|||||||---|||||||||||||-||--||||----|||||-|||||------|||||-|  3 [R] COG1694 Predicted pyrophosphatase
||||||--|--||-----||||----|||-||--||||----|||||-||-||--|--|||-||--  3 [K] COG1733 Predicted transcriptional regulators
----------------||----||||----|----|||----||||||||-----|||||||||--  3 [NU] COG1886 Flagellar motor switch/type III secretory pathway protein
|-----|------------------------|--|||------------|--|-------------  3 [M] COG1887 Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC
--||||--|--|-||--|-|||----|||-|||-||||-|--|||||-||--|--|---|||||--  3 [C] COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family
----------------|-||-|---||||||----|||----|||||-||--|--|---|||||||  3 [T] COG2200 FOG: EAL domain
||||||||||-|-----|-|||----|---||||||||----|||||-||||||||---|||||--  3 [R] COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
-|-|--||------|--|||||--|||---||||||||-|--|||||-||||-||||||-||-|--  3 [R] COG2252 Permeases
---|---------------|-|--------||||||||----|||||-||||||||----------  3 [R] COG2333 Predicted hydrolase (metallo-beta-lactamase superfamily)
---------------------|--------||||||||----|||||-|--|---|---||||---  3 [K] COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
-----------|-||---||-------|||||||-|||----|||||-||-|-|||--||||||--  3 [E] COG2755 Lysophospholipase L1 and related esterases
--|-||--|----||---||||----|||--|||||-|||--|||||-|||--|||---|||||--  3 [L] COG2801 Transposase and inactivated derivatives
--------------------|---------|-||||||----------||--|--|----------  3 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain
--------------------|---------||||||||----|||||-||--|--|---|||||--  3 [KT] COG3279 Response regulator of the LytR/AlgR family
-----------------------------------|-|----|||||-|------------||---  3 [S] COG3394 Uncharacterized protein conserved in bacteria
------||----------------------||---|||-------|--------------------  3 [S] COG3595 Uncharacterized conserved protein
--------------------|---------|---||||-----------|-|-------||-|---  3 [S] COG3708 Uncharacterized protein conserved in bacteria
------------------------------|-||||-|----|||-|-------------------  3 [G] COG3775 Phosphotransferase system, galactitol-specific IIC component
------------------------------||||||||----------------------------  3 [L] COG3935 Putative primosome component and related proteins
-------------------------------|--||------------------------------  3 [R] COG4814 Uncharacterized protein with an alpha/beta hydrolase fold
-------------------------------||-|||-----------------------------  3 [G] COG4975 Putative glucose uptake permease
||||||--|||||-|-|-||||||--|||||---||||----|||||-||-|||||||||||||--  2 [H] COG0001 Glutamate-1-semialdehyde aminotransferase
|||||||||||||||||||||||||||||||||||||||||||||||-||||||||||||||||||  2 [E] COG0006 Xaa-Pro aminopeptidase
---|||----||||||--||-|||---||--|||||||-|||-------|-----|---|||||||  2 [C] COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
||||||-|||---|||--||-|----|||--|-||||-----|||||-||-||------|--|---  2 [P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  2 [C] COG0055 F0F1-type ATP synthase, beta subunit
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  2 [C] COG0056 F0F1-type ATP synthase, alpha subunit
|||||||||||||||||||||---|||||||||||||||-||||||||||||||||||||||||||  2 [G] COG0061 Predicted sugar kinase
||||--||||--||----||-------||--|---|-|----||||--|-|---------|||---  2 [E] COG0076 Glutamate decarboxylase and related PLP-dependent proteins
|||||||||||||||-||||||----||||||--||||----||||||||||||||--||||||--  2 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase
|||||||||||||||-||||-|----||||||--||||----|||||-|||||--|||||||||--  2 [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases
||||||-||||||||-||||||----||||||||||||----||||||||||||||||||||||--  2 [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||--  2 [G] COG0149 Triosephosphate isomerase
||||----|||||||-||||||||||||||||||||||||||---|---|---|||||||||||||  2 [J] COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases
--||||--|----|||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
--||||--|----|||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
-------------||-|||||||||-||||||||||||||||||||||||||||||||||||||--  2 [H] COG0196 FAD synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [J] COG0199 Ribosomal protein S14
-------------||-|||||||||||||||||||||||||||||||-||||||||||||||||||  2 [S] COG0217 Uncharacterized conserved protein
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  2 [C] COG0224 F0F1-type ATP synthase, gamma subunit
||||-||||||-|||-||-||------||||-||-|||-||-|||||-|||||--|||--||||||  2 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
--|----------||-||||||||||||||||||||||||||||||||||||||||||||||||||  2 [IQ] COG0236 Acyl carrier protein
-|||--||-|---||-||||-|----|||-|--|||||----|||||-||||||||||||||||--  2 [D] COG0239 Integral membrane protein possibly involved in chromosome condensation
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0258 5'-3' exonuclease (including N-terminal domain of PolI)
--|----------|||-|--||||--||||||||||||||||||||||||||||||---|||||-|  2 [H] COG0262 Dihydrofolate reductase
|-||------||-||-||||||||||||||||||||||----||||||||||||||||||||||||  2 [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
-------------||-|||||||||||||||||||||||||||||||||||||||||||-||||||  2 [J] COG0267 Ribosomal protein L33
--||-------------||-||--|||||-||||||||||||||||||||||||||-|||||||||  2 [C] COG0280 Phosphotransacetylase
--|--------------|||||--|||||-||||||||||||||||||||||-||-|||-|||-||  2 [C] COG0282 Acetate kinase
||||||||||||-|---|-|-|||--|||||---||||----||||||||||-||||||||-|---  2 [P] COG0306 Phosphate/sulphate permeases
----------------||||||---||||||||||||||-|||||||-||||||||||||||||-|  2 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases
|-||------------|||||||||||||||||||||||||||||||-||||||||||||||||||  2 [L] COG0322 Nuclease subunit of the excinuclease complex
||||--||||---|||---|||||||||-|||||||||||--||||||||||-||||||-------  2 [S] COG0327 Uncharacterized conserved protein
-------------||-||||||||||----||||||||||||||||||||||||||||||||||||  2 [J] COG0333 Ribosomal protein L32
|-|-||----|||||-||||-|--|-||||||||||||----|||||-||||||||||||||||--  2 [E] COG0345 Pyrroline-5-carboxylate reductase
|||||||||||||||-||-|||--|-||||||||||||----|||||-||||||||||||||||--  2 [H] COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  2 [C] COG0355 F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit)
|-||||--|-|||||||-||-|-----||--|--||||----|||||-||-||--||-||||||--  2 [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases
|-|||||||-|||||-||||-|--|-|||||--|||||----|||||-||--||||||||||||--  2 [R] COG0388 Predicted amidohydrolase
||||--||||------||||------|||||---|||-|||||||-|--|--|--|---||||---  2 [S] COG0392 Predicted integral membrane protein
-------------||---||-|||-------|--||||----|||----|--|------||||-||  2 [R] COG0400 Predicted esterase
||||||||||||||||||||||--||||||||--||||----|||||-||----------|-----  2 [L] COG0420 DNA repair exonuclease
||||||||||||||||||||||---|||||||||||||----|||||-||||||||||||||||||  2 [M] COG0438 Glycosyltransferase
|||||||||||||||-||||||--||||||||||||||||||||||||||||||||||||||||-|  2 [FE] COG0462 Phosphoribosylpyrophosphate synthetase
---|||----|||||---||-|||--||||-|||||||-|||||||||||||||||---|||||||  2 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes
||||||-||||||||-||||||----||||||||||||----||||||||||||||||||||||--  2 [EH] COG0512 Anthranilate/para-aminobenzoate synthases component II
--|---------||||--||||--|-|---||--||||----|||||-||||||||---||-||--  2 [L] COG0514 Superfamily II DNA helicase
---|||----||-||||-||-|||--||||||||||||||||-|-|--|||||--||--|--|---  2 [RTKL] COG0515 Serine/threonine protein kinase
|||||||||||||||-||||||-|-|||||||||||||----|||||-||||||||||||||||--  2 [F] COG0518 GMP synthase - Glutamine amidotransferase domain
|||||||||||||||--|||-|----||||||||||||----|||||-|||||--|---|||||--  2 [G] COG0524 Sugar kinases, ribokinase family
|-||--|||----|--|-||-|--|||||-|||||||||---|||||-||||||||||||||||--  2 [R] COG0546 Predicted phosphatases
--------|----||-|||||||||||||||||||||||||||||||-||||||||||||||||||  2 [J] COG0566 rRNA methylases
|||||||||||||---||||||--|-|||||--|-||-----|||||-||--||||||||||||||  2 [G] COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase
|-------|--|-|||-||-||---|----||||||||-|||||||||-||||--|---|||||--  2 [G] COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)
---|||-|--|-||||-|-|||--|-||||||||||||-||||||||-||||---|---|||||--  2 [C] COG0584 Glycerophosphoryl diester phosphodiesterase
||||--||-|-------|||||----||||||||||||||||--------------||||||||||  2 [R] COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily
----------|-|||-||||||---|-|||||||||||----|||||-|||||--|||||||||||  2 [R] COG0612 Predicted Zn-dependent peptidases
|||||||||||||||-||-----|--||||-|-|||||----||||||||||||||--||--||--  2 [E] COG0620 Methionine synthase II (cobalamin-independent)
--||||||--|||||--|--||----||||||||||||----|||||-||||||||||||||||--  2 [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases
||||||||||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [C] COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  2 [U] COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase)
--|----------||||-||--||--||||-|---|||----|||-|-||-|---|||-||-|---  2 [P] COG0659 Sulfate permease and related transporters (MFS superfamily)
---|||----|||||-||||||---|||||-|--||||----|||||-||--|--||--||-||--  2 [C] COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)
||||--||-|-|-||||-||||--|-||||||||||||----|||||-|||||--|||-|||||||  2 [I] COG0671 Membrane-associated phospholipid phosphatase
-------------|||----||||-|||||-||||||||||||||||||||||||||||||-----  2 [L] COG0692 Uracil DNA glycosylase
-||||||||||||||-|-||||--||-||-|--|||||-||||||||-||-||--|--||||||--  2 [R] COG0693 Putative intracellular protease/amidase
---|---------||-|-||-|----|----|--||||----|||||-|||-|--|---|||||--  2 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epimerases
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  2 [U] COG0706 Preprotein translocase subunit YidC
|||-----||---||---|||---|-----||||-||-----|||||||||||--||||-------  2 [C] COG0716 Flavodoxins
|||||||||||||----|||-||||-||||||||||||----|||||-----|------|||||--  2 [O] COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component
|||||||||||||---||||||----|--|||--||||----|||||-||||||||||||||||--  2 [R] COG0730 Predicted permeases
||||-|-||----------|-------||--|||||--|||||||-|-|||||---|||-||-|-|  2 [V] COG0732 Restriction endonuclease S subunits
|--|----|----||-|||--|--|-|---|||-||||-|--|||||-|-||---|||-||-|---  2 [F] COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases
----------------||||||--||||||||--||||----||||||||||||||||||||||||  2 [M] COG0739 Membrane proteins related to metalloendopeptidases
----------------||||||||||||||||||||||----||||||||||||||||||||||||  2 [OU] COG0740 Protease subunit of ATP-dependent Clp proteases
-----------------|||||----||||||||||||----||||||||||||||||||||||--  2 [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein)
-------------|||||||||--||----||||||||----||||||||||||||||||||||||  2 [O] COG0760 Parvulin-like peptidyl-prolyl isomerase
----------------||||||||||||||||||||||----||||||||||||||||||||||||  2 [M] COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase
|-||--|||----|||-|||-|--||-||-|----|||----|||||-|||||--|||||||||--  2 [T] COG0784 FOG: CheY-like receiver
|-|---|-|----|---|||------|||-|----||--------------|--|----|------  2 [P] COG0798 Arsenite efflux pump ACR3 and related permeases
|||------|-|----|--|||--------||||||||----|||||-||||-|||||||||----  2 [O] COG0826 Collagenase and related proteases
-|-------------------------|||||||||||------------|-----||-|--|---  2 [L] COG0827 Adenine-specific DNA methylase
--||--|||--------|||-|--||----|----|||----|||||-||--|--||||||-||--  2 [NT] COG0840 Methyl-accepting chemotaxis protein
----------------||||||--|||---|-||||||----|||||-||||||||||||||||||  2 [M] COG0845 Membrane-fusion protein
------------------||-|----|||-|---||||----||||||||||||||||||||||||  2 [P] COG0861 Membrane protein TerC, possibly involved in tellurium resistance
-|-||||----------|-|||----------|--|-|----|||||-|-|-||-|||-|||||--  2 [L] COG0863 DNA modification methylase
||||--||-|||-|||-|-|-|--|||||-||||||||----|||||-||-|-|||---|||||--  2 [R] COG1011 Predicted hydrolase (HAD superfamily)
----------------||||||--||-||-||||||||----|||||-||||||||||||||||-|  2 [R] COG1040 Predicted amidophosphoribosyltransferases
|||---|||||||---|-||-|----||||||-|-|||-------|--||-----|---|||||-|  2 [F] COG1051 ADP-ribose pyrophosphatase
--------|---|||--|||----|||||-||-|||||----|||||--|||---|---||||---  2 [G] COG1070 Sugar (pentulose and hexulose) kinases
---|||----||||||--||-|||---||--|||||||-|||-------|-----|---|||||||  2 [C] COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
-----------------|---|--------||||||||----------------------------  2 [J] COG1098 Predicted RNA binding protein (contains ribosomal protein S1 domain)
-----------------|--||---||||-||||||||--|||||||-||||---|----------  2 [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)
||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||--  2 [P] COG1117 ABC-type phosphate transport system, ATPase component
--------|----------|||-----||-|||||||-----|||||--|------||-||||---  2 [E] COG1125 ABC-type proline/glycine betaine transport systems, ATPase components
------------------||||-||-|---||||||||----|||||-||||||||||||||||--  2 [P] COG1135 ABC-type metal ion transport system, ATPase component
-||---||-|||||||-||||----|----||||||||||||------|----||-----------  2 [R] COG1161 Predicted GTPases
--|-------------|||||----||||||||||||||||||||||-||||||||------|---  2 [R] COG1162 Predicted GTPases
--||-------------|--||||||-----|||||||||||------|-------||||||||--  2 [E] COG1164 Oligoendopeptidase F
--|-------------||||||||||||||||||||||----|||||-||||||||||||||||||  2 [M] COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes
-------------------|----------||--||||-||||||||--||----|---||-|---  2 [I] COG1182 Acyl carrier protein phosphodiesterase
----------------||||||||||||||||||||||-|--||||||||||||||||||||||||  2 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases
||-|-|||-|||----|-||-||||||||||----|||--|||||||-||--||||||||||||||  2 [D] COG1192 ATPases involved in chromosome partitioning
||||||||--|||||||-|||-----|||-||||||||----|||||-||||||||-------|--  2 [KL] COG1199 Rad3-related DNA helicases
------|---------|||||||||-|||||--|||||--||||||||||||||||||||||||--  2 [I] COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase
-----------------|||----------|----||-----|||||-||-----|----------  2 [KT] COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
||||||||||||||||-|||-|||||||||||||||||----|||-|----|---|------||--  2 [R] COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
---|-------|-||---||-|----||||-|--||||----|||||-|||----|---||||---  2 [C] COG1252 NADH dehydrogenase, FAD-containing subunit
--------------------|----||---||||||||-|||||||||||-|---|-------|--  2 [G] COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific
--------------------|----||---||||||||||||||||||||-|---|-------|--  2 [G] COG1264 Phosphotransferase system IIB components
--------------------|---|-|-----||||||-|--|||-|-||--------|||||---  2 [P] COG1283 Na+/phosphate symporter
-----------------|--||||------||||||||----------------------------  2 [S] COG1302 Uncharacterized protein conserved in bacteria
|-|---||||||----||||-|-----||||----|||-----------||||--|---||-||--  2 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases
--|||||||||||||-||-|-|--|||||-||||||||----|||||-||--||||--||||||--  2 [Q] COG1335 Amidases related to nicotinamidase
----------------||------||----|----|||----|||||-||-----|||||||||--  2 [N] COG1344 Flagellin and related hook-associated proteins
-----------------|------------|||-|||-----|||-|-||||-||-|||||-|---  2 [M] COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
|||-||||||---||-||--||-----||-||--||||----|||||-|-----------|-----  2 [ER] COG1387 Histidinol phosphatase and related hydrolases of the PHP family
-------------------|||----|--||||||||||-|||||||-||||||||--||||||--  2 [P] COG1393 Arsenate reductase and related proteins, glutaredoxin family
|-|-------|-----|--|-|||--||||||---|||----|------------||||-|-|---  2 [R] COG1408 Predicted phosphohydrolases
||||||||||------||--||--||----|||||||||-|||||-|---------|||||-----  2 [R] COG1418 Predicted HD superfamily hydrolase
----------------||||-|----|---||--||------|||||-||||||||---|||||||  2 [S] COG1434 Uncharacterized conserved protein
-----------------|--||----|||-||||||||||||------------------------  2 [R] COG1461 Predicted kinase related to dihydroxyacetone kinase
--------------------||-||-|---||||||||----|||||-||||||||||||||||--  2 [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen
-|||--|----------|-||-----|---|----|--||---|||--|--|--|-|||-------  2 [S] COG1479 Uncharacterized conserved protein
----||--|-|--|||-||||-||--|---||||||||||--||||||||||||||||-|||||||  2 [I] COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes
------|------|-----|-------|||||---||--|--|||--------||-----------  2 [G] COG1554 Trehalose and maltose hydrolases (possible phosphorylases)
--|--------------|||||----|||-||||||||----|||||-||||||||--|-------  2 [L] COG1555 DNA uptake protein and related DNA-binding proteins
---|-------------||||-----||||-|--|||-----|||||-|-||--------------  2 [H] COG1575 1,4-dihydroxy-2-naphthoate octaprenyltransferase
||||--||||||||||---------|-----|||||------------------------------  2 [I] COG1577 Mevalonate kinase
||||||--||||-||-|-||||||--|||||---||||----|||||-||-||||||||||||---  2 [H] COG1587 Uroporphyrinogen-III synthase
----||------------||||--|-----||-|-|||-|--|||-|-||---|||--------||  2 [V] COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF
--------------------|-||||||||||||||||----|||||-||||||||---|||||||  2 [M] COG1686 D-alanyl-D-alanine carboxypeptidase
---|----|----------|||-----||-|||||||-----|||-|--|-----|||-||||---  2 [M] COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
--------------------||----||||||||||||----|||||-||||-|||||||||||--  2 [E] COG1760 L-serine deaminase
-||-||||-|-||---||---|----|||-|----|-|--|||||||-||---|||---||-||--  2 [O] COG1765 Predicted redox protein, regulator of disulfide bond formation
-------------------------|------|--||-------------|---------------  2 [R] COG1783 Phage terminase large subunit
---------------------|------------||||----|||||-||--||||---|||||||  2 [S] COG1806 Uncharacterized protein conserved in bacteria
-----------|-----|-|||---||||-||||||||-|--|||||-|||||------|||||--  2 [G] COG1820 N-acetylglucosamine-6-phosphate deacetylase
|-|-|-|||-|||-|-||||||----||||||-|||||----|||||--|-|-|||---|||||||  2 [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family
|-------|-----------|---------||||||------|||||-|-||---|----------  2 [C] COG1882 Pyruvate-formate lyase
------------------||-|----||||||--||||----|||-|--|-----|--|||-----  2 [S] COG1937 Uncharacterized protein conserved in bacteria
--|---||---------|--------|---||||-|||----|||||-|-----------------  2 [KT] COG1983 Putative stress-responsive transcriptional regulator
--------------------||-||-|---||||||||----|||||-||||||||||||||||--  2 [P] COG2011 ABC-type metal ion transport system, permease component
----||-----|-||--|||||--------||-|||||----|||-|-|-||-|||---|||||--  2 [G] COG2017 Galactose mutarotase and related enzymes
--|||||||-||--|-|----|----|||--|||||||----|||||-||||---|||||||||--  2 [Q] COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism
---|||------------||-|-----||-|---||------|||||--|-----|---||-||--  2 [P] COG2060 K+-transporting ATPase, A chain
--------|----|--||-|||----|||-||||||||-----------|--||||||||||-|--  2 [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase
--||---------------|-|-----|||||---|||----|||||-||---||---||||||--  2 [P] COG2076 Membrane transporters of cations and cationic drugs
--------|-----------|----|----|---||||----------------------------  2 [M] COG2088 Uncharacterized protein, involved in the regulation of septum location
---||||||-|||-------||----||||-----|||--------|--|-----|---|||||--  2 [S] COG2096 Uncharacterized conserved protein
||||--||---------|||-|----|-------||||----------||---------|||--||  2 [P] COG2111 Multisubunit Na+/H+ antiporter, MnhB subunit
--|----------------------|-----||--||-----|||||--|-----|---||||---  2 [E] COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components
---------|---|------|---------|||||||-----|||||-||||--------------  2 [P] COG2116 Formate/nitrite family of transporters
||||----||-|-------|-|----||||--||||||-|--|||||--|--|--|---|||||--  2 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
---|||------------||-|-----||-|---||------|||||--|-----|---||-||--  2 [P] COG2156 K+-transporting ATPase, c chain
----------------||||||||------||||||||----|||||-|||||--|--|---||--  2 [NU] COG2165 Type II secretory pathway, pseudopilin PulG
---------------------------||--|---|||----|||||-||-----|---|||||-|  2 [F] COG2169 Adenosine deaminase
-----------------|||-|||---||-|---||||----------------------------  2 [T] COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase)
--------------------|----||---||||||||-|||||||||||||---|-------|--  2 [G] COG2190 Phosphotransferase system IIA components
--|-----------------||---|----||||||||----|||||-|-||------|-|--|--  2 [E] COG2195 Di- and tripeptidases
------------------||-|----|||-||||||||----|||||-||||||||---|||||--  2 [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
|-||----|-----|-||||-|||-||||||----|||----|||||-||--|--|--||||||--  2 [T] COG2202 FOG: PAS/PAC domain
------------------||-|-----||-|---||------|||||-||-----|--|||-||--  2 [T] COG2205 Osmosensitive K+ channel histidine kinase
---|||------------||-|-----||-|---||------|||||--|-----|--|||-||--  2 [P] COG2216 High-affinity K+ transport system, ATPase chain B
-------|------|--|--||----|---||||||||----|||||-||||-|||---|||----  2 [F] COG2233 Xanthine/uracil permeases
--|-----------|-----|---------|----||||---|||||-||||-||||||-|-||--  2 [R] COG2249 Putative NADPH-quinone reductase (modulator of drug activity B)
-|||--||-||||---||||||||--||||||||||||----|||||-||-|||||---|||||--  2 [R] COG2262 GTPases
------||-----||-||||||||--|||-||||||||----|||||-||||||||--||||||--  2 [J] COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase
---|--|--|--|---|----|---|-------|||||---------------------||||---  2 [E] COG2309 Leucyl aminopeptidase (aminopeptidase T)
--------------------||----|----|||-||-----|||||--|-----|---|--||--  2 [S] COG2315 Uncharacterized protein conserved in bacteria
---|||-----||--------|----||||----||||-----------|-----|---||||---  2 [R] COG2329 Conserved protein involved in polyketide biosynthesis related to monooxygenase
--------------------||----|||-||||||||----------------------------  2 [S] COG2357 Uncharacterized protein conserved in bacteria
-------------||------|-----||--|---|---------|---|-----|---|---|--  2 [T] COG2365 Protein tyrosine/serine phosphatase
----||----|||--------|----|||||---|||-----------------------------  2 [R] COG2409 Predicted drug exporters of the RND superfamily
---------------------|----||||||||-|||-----------|---------|------  2 [TQ] COG2508 Regulator of polyketide synthase expression
-------------------|||---|-||-|--|||||--------------||-|-----|----  2 [E] COG2856 Predicted Zn peptidase
--------------------|----------|||-|------|||||-|--||------||-||--  2 [P] COG3142 Uncharacterized protein involved in copper resistance
-------------------------------|--||------|||||-||----------|-||--  2 [S] COG3152 Predicted membrane protein
-------------------|-|----|---||--||------|||-|--|-|-------|--|---  2 [S] COG3238 Uncharacterized protein conserved in bacteria
--|----------------|-------||--|--||------||||---|-----|----|||---  2 [S] COG3247 Uncharacterized conserved protein
-----------------------------------||-----|-||----|-|-|-----------  2 [S] COG3299 Uncharacterized homolog of phage Mu protein gp47
--------------------||---------|-|||-|----|||-----------------|---  2 [S] COG3412 Uncharacterized protein conserved in bacteria
--------------|----------------|||-|-|--------------|-------------  2 [S] COG3538 Uncharacterized conserved protein
-----------------|---|--------||---|||----------------------------  2 [S] COG3584 Uncharacterized protein conserved in bacteria
------------------||-|----||||||||||||-|--------------------------  2 [D] COG3599 Cell division initiation protein
-------------------------------||--|-------|||---||-|--------|----  2 [K] COG3617 Prophage antirepressor
-------------------------------|-|-||------||-----||--------------  2 [S] COG3646 Uncharacterized phage-encoded protein
---|----|----------------------|||||||----------------------------  2 [S] COG3679 Uncharacterized conserved protein
-------------------------------||-||||----|||---------------------  2 [L] COG3723 Recombinational DNA repair protein (RecE pathway)
--||----|-|-|----|||||--|||---||||||-||||||||||-||||-|||--||||||--  2 [E] COG3842 ABC-type spermidine/putrescine transport systems, ATPase components
--------------------||--------|---|||-----------------------------  2 [S] COG3878 Uncharacterized protein conserved in bacteria
------------------------------||||-|||----------------------------  2 [S] COG3883 Uncharacterized protein conserved in bacteria
------------------------------|----||---------|-------------------  2 [K] COG3933 Transcriptional antiterminator
---|---------------------------|---|-|-------||-||----------------  2 [R] COG3979 Uncharacterized protein contain chitin-binding domain type 3
--------------------------|||-|-||||||---------------------|-|----  2 [S] COG4129 Predicted membrane protein
--------------------|---------||||||||----------------------------  2 [S] COG4224 Uncharacterized protein conserved in bacteria
----------------|--------------||-|||-----|||---------------------  2 [L] COG4570 Holliday junction resolvase
------------------|||--------------|------|||-|-------------------  2 [QC] COG4576 Carbon dioxide concentrating mechanism/carboxysome shell protein
--------------------|--------------|------|||-|-------------------  2 [E] COG4816 Ethanolamine utilization protein
-----------------------------------|-|-----------------------|----  2 [R] COG4821 Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain
--------------------|--------------|---------------|--------------  2 [V] COG4823 Abortive infection bacteriophage resistance protein
-----------------|-----------------|----------|-------------------  2 [Q] COG4869 Propanediol utilization protein
---|||--||-||----|||||----||||||--||||----|||||--|-----|---|||||--  2 [MR] COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily
--------------------|---|-|||||---||||----|||||-||||||||---|||||||  2 [L] COG4974 Site-specific recombinase XerD
------------------||----------|---||||----------------------------  2 [R] COG4980 Gas vesicle protein
--------------------|-----|||--||-||||----|||||-|-||-------|-|-|--  2 [CO] COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components
-------------------------------|--|||-----------------------------  2 [S] COG4990 Uncharacterized protein conserved in bacteria
-----------------|--|----------|---|------------------------------  2 [S] COG5341 Uncharacterized protein conserved in bacteria
--|--------------------------------|-------------------|----|-||--  2 [S] COG5361 Uncharacterized conserved protein
-----------------------------------|||--------------|-------------  2 [L] COG5377 Phage-related protein, predicted endonuclease
----------------------------------||-|----------------------------  2 [M] COG5386 Cell surface protein
-------------------|---------------|------|||-|-----|--|----------  2 [R] COG5525 Bacteriophage tail assembly protein
--------------------------------|-||------------------------------  2 [S] COG5546 Small integral membrane protein
--------------------------|----|---|||-------------------------|--  2 [S] COG5646 Uncharacterized conserved protein
--|-----|-----------------|--------||--------------------------|--  2 [S] COG5658 Predicted integral membrane protein
|||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||--  1 [E] COG0002 Acetylglutamate semialdehyde dehydrogenase
||-|||-|-||-|||-|-|||------|||-----|-|----------------------------  1 [P] COG0003 Oxyanion-translocating ATPase
|||-||--||-|-||-||||-|----|||-||--|||||---|||||--|--||||---|||||--  1 [P] COG0004 Ammonia permease
|||||||||||||||-||||-------||||-||-|||----|--||--|--|------||-|---  1 [F] COG0005 Purine nucleoside phosphorylase
||||||--|||||||-|-||||----|||||---||||----||||||||--||||---|||||--  1 [H] COG0007 Uroporphyrinogen-III methylase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0008 Glutamyl- and glutaminyl-tRNA synthetases
||||||||||||||||||||||||||||||||||||||||||||||||||||||||---|||||||  1 [J] COG0009 Putative translation factor (SUA5)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0012 Predicted GTPase, probable translation factor
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0013 Alanyl-tRNA synthetase
--|----------||-||||-|--|-||||||||-|||----|||||-||||||||--||||||--  1 [E] COG0014 Gamma-glutamyl phosphate reductase
||||||||||||-||-||||||----||||||||||||----||||||||||||||||||||||--  1 [F] COG0015 Adenylosuccinate lyase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0016 Phenylalanyl-tRNA synthetase alpha subunit
||||||||||||||||--||||--||----|||||||||||||||||||-|||-------------  1 [J] COG0017 Aspartyl/asparaginyl-tRNA synthetases
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0018 Arginyl-tRNA synthetase
|||-||--||---||-||||-|----||||||-|||||----||||||||||||||||||||||--  1 [E] COG0019 Diaminopimelate decarboxylase
||||||||||||||||||||||||||||||||||||||----||||||||||||||||||||||||  1 [I] COG0020 Undecaprenyl pyrophosphate synthase
||||||||||||||||||||||||||||||-|||||||||||||||||||||||||||||||||||  1 [J] COG0024 Methionine aminopeptidase
---|||----||-||-||||-|----||||-|||||||----|||||-||||||||---|||||--  1 [F] COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)
---|--||---|----|-|||------||||----|||----|||||-||--||||---||-||--  1 [H] COG0029 Aspartate oxidase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0030 Dimethyladenosine transferase (rRNA methylation)
--||||-|--|||||-||||||----||||||||||||----||||||||||||||||||||||--  1 [E] COG0031 Cysteine synthase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase
|--|---|--|||||-||||||--|-|||-|||||||||||||||||-||||-|||--||||||--  1 [F] COG0035 Uracil phosphoribosyltransferase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [D] COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control
||||----||||-||-||||-|----||||||--||||----|||||||||||||---||||||--  1 [E] COG0040 ATP phosphoribosyltransferase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase
||||----||---|||||||||||||||||||||||||----|||||-||||||||||||||||||  1 [J] COG0042 tRNA-dihydrouridine synthase
|||||||||||||||-||||||----||||||||||||----|||-|--|--|--|||||||||--  1 [F] COG0044 Dihydroorotase and related cyclic amidohydrolases
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0048 Ribosomal protein S12
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0049 Ribosomal protein S7
---------|---||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0050 GTPases - translation elongation factors
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0051 Ribosomal protein S10
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0052 Ribosomal protein S2
||||||||||||||||||||||||||||||||||||||-|||||||||||||||||||||||||--  1 [G] COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase
|||----|||||-|--||||-|----||||||-|||||----||||||||||||||||||||||--  1 [EH] COG0059 Ketol-acid reductoisomerase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0060 Isoleucyl-tRNA synthetase
||||||||||||||||||||-|----||||||--|||-----|||||-||--||||||||||||--  1 [G] COG0063 Predicted sugar kinase
||||----||-||||-||||||||||||||||||||||||||-------|---|||||||||||||  1 [J] COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog)
||||--||||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0065 3-isopropylmalate dehydratase large subunit
|||---||||||-||-||||-|----||||||-|||||----||||||||||||||--||||||--  1 [E] COG0066 3-isopropylmalate dehydratase small subunit
|||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||--  1 [E] COG0067 Glutamate synthase domain 1
|||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||--  1 [E] COG0069 Glutamate synthase domain 2
|||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||--  1 [E] COG0070 Glutamate synthase domain 3
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0072 Phenylalanyl-tRNA synthetase beta subunit
||||||--||||-||-||||-|----||||||-|||||----|||-||||||||||--||||||--  1 [E] COG0077 Prephenate dehydratase
|||||||||||||||-||||-|---|||||||||||||--|-||||||||||||||--||||||--  1 [E] COG0078 Ornithine carbamoyltransferase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0080 Ribosomal protein L11
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0081 Ribosomal protein L1
||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||--  1 [E] COG0082 Chorismate synthase
-|-|||||-||||||-||||-|----||||||-|||||----|||||||-|||---|||-------  1 [E] COG0083 Homoserine kinase
|||---||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0084 Mg-dependent DNase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0087 Ribosomal protein L3
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0088 Ribosomal protein L4
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0089 Ribosomal protein L23
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0090 Ribosomal protein L2
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0091 Ribosomal protein L22
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0092 Ribosomal protein S3
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0093 Ribosomal protein L14
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0094 Ribosomal protein L5
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0096 Ribosomal protein S8
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0097 Ribosomal protein L6P/L9E
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0098 Ribosomal protein S5
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0099 Ribosomal protein S13
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0100 Ribosomal protein S11
|||||||||||--||||||||||||||||||||||||||-||||||||||||||||||||||||||  1 [J] COG0101 Pseudouridylate synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0102 Ribosomal protein L13
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0103 Ribosomal protein S9
||||||||||||-||-||||||----||||||||||||----||||||||||||||||||||||--  1 [F] COG0104 Adenylosuccinate synthase
|||||||||||||||||-||-||||||||||--|||||----|||||-||||||||||||||||||  1 [F] COG0105 Nucleoside diphosphate kinase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0107 Imidazoleglycerol-phosphate synthase
---|||--|-|||||-|-||-|----||||----||||----||||||-|--|--|---|||||||  1 [O] COG0109 Polyprenyltransferase (cytochrome oxidase assembly factor)
||||||||||||||||||||-|||||||||||||||||-|||||||||||||||||||||||||||  1 [E] COG0112 Glycine/serine hydroxymethyltransferase
||||||--|||||||-|-||||||--|||||---||||----|||||-||-|||||||||||||||  1 [H] COG0113 Delta-aminolevulinic acid dehydratase
--||------|||||---|--|||--||||----||||----|||||-||||||||||||||||||  1 [C] COG0114 Fumarase
-|----|||||-|-----|-||--------||||||||----||||||||||||||----------  1 [L] COG0116 Predicted N6-adenine-specific DNA methylase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0118 Glutamine amidotransferase
|||--|||||||-||-||||-|----|||||--|||||----||||||||||||||--||||||--  1 [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases
||||||||||||||||--||-|||||----||||||------||||||||||||||---|||||--  1 [G] COG0120 Ribose 5-phosphate isomerase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0124 Histidyl-tRNA synthetase
||||||||||||||||||||||||||||||-|||||||||||||||||||||||||||||||||||  1 [F] COG0125 Thymidylate kinase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||--  1 [G] COG0126 3-phosphoglycerate kinase
||||||||||||||||||||||||||||||||||||||----|||||-||||||||--||||||--  1 [F] COG0127 Xanthosine triphosphate pyrophosphatase
||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||--  1 [E] COG0128 5-enolpyruvylshikimate-3-phosphate synthase
|||----||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1 [EG] COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase
||||||||||||||||||||||||||||||||||||||||--||||||||||||||--||||||||  1 [J] COG0130 Pseudouridine synthase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0131 Imidazoleglycerol-phosphate dehydratase
||||---|||---||-|||||||---||||||-|||||----||||||||||||||||||||||--  1 [E] COG0133 Tryptophan synthase beta chain
||||||-||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1 [E] COG0134 Indole-3-glycerol phosphate synthase
||||||-||||||||-||||-||---|---||-|||||----||||||||||||||||||||||--  1 [E] COG0135 Phosphoribosylanthranilate isomerase
|||||-|||||||||-||||-|||--||||||-|||||----||||||||||||||||||||||||  1 [E] COG0136 Aspartate-semialdehyde dehydrogenase
||||||--||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0137 Argininosuccinate synthase
--||||--|----||-||||||----||||||-|||||----||||||||||||||--||||||--  1 [F] COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0139 Phosphoribosyl-AMP cyclohydrolase
||||-----|||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0140 Phosphoribosyl-ATP pyrophosphohydrolase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0141 Histidinol dehydrogenase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0143 Methionyl-tRNA synthetase
-|-|--||||||||||-|||||||--|||-||||||||----|||||-||||||||--||||||--  1 [J] COG0144 tRNA and rRNA cytosine-C5-methylases
-||--|--|||||||-|-||-------|-------|-|------------------||-|||||--  1 [EQ] COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||--  1 [G] COG0148 Enolase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0150 Phosphoribosylaminoimidazole (AIR) synthetase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||||||||||--  1 [F] COG0151 Phosphoribosylamine-glycine ligase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||||  1 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase
||||--||||||-|--|||||-----|||||-||-|||----|||||-||||||||||-||-||--  1 [H] COG0157 Nicotinate-nucleotide pyrophosphorylase
||||||-||||||||-||||-||---||||||-|||||----||||||||||||||||||||||--  1 [E] COG0159 Tryptophan synthase alpha chain
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0162 Tyrosyl-tRNA synthetase
||||||||||||||||||||||||-|||||||||||||----|||||-||||||||||||||||||  1 [L] COG0164 Ribonuclease HII
||||||--||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0165 Argininosuccinate lyase
-|-|||----||||||||||||||||||||||||||||-|||||||||||||||||||||||||--  1 [G] COG0166 Glucose-6-phosphate isomerase
|||||||||||||||-||||||----||||||||||||----||||||||||||||||||||||--  1 [F] COG0167 Dihydroorotate dehydrogenase
||||--||||--|||-||||||--||------||||||-||||||||-||||-||---||||----  1 [P] COG0168 Trk-type K+ transport systems, membrane components
|||||||||||||||-||||||--||||||||||||||||||||||||||--||||||||||||--  1 [H] COG0171 NAD synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0172 Seryl-tRNA synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0173 Aspartyl-tRNA synthetase
|||||||||||||||-||||-|----||||-|||||||----|||||-||||||||||||||||||  1 [E] COG0174 Glutamine synthetase
||||||||||||||||||||||||||||||||||||||----||||||||||||||||||||||||  1 [L] COG0177 Predicted EndoIII-related endonuclease
|||||||||||||||---||-|----||||----||||----|||||-||-|-|||--||||||--  1 [Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0180 Tryptophanyl-tRNA synthetase
||||||--|||||||-|-||||||--|||||---||||----||||||||-|||||||||||||||  1 [H] COG0181 Porphobilinogen deaminase
||||||||||||||||--|-||---||||||||-||||----|||||-|||----|||-|||||||  1 [I] COG0183 Acetyl-CoA acetyltransferase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0184 Ribosomal protein S15P/S13E
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0185 Ribosomal protein S19
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0186 Ribosomal protein S17
--||||----||-||-|||||||||||||||||||||||||||||||||||||-||||||||||||  1 [H] COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase
-------------||-||||||--||||||||||||||||||||||||||||||||||||||||--  1 [H] COG0192 S-adenosylmethionine synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0193 Peptidyl-tRNA hydrolase
-------------|||||||||||--||||||||||||||||||||||||||||||||||||||||  1 [F] COG0194 Guanylate kinase
|||||||||||||---||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0195 Transcription elongation factor
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0197 Ribosomal protein L16/L10E
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0198 Ribosomal protein L24
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0200 Ribosomal protein L15
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0201 Preprotein translocase subunit SecY
||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0203 Ribosomal protein L17
-------------||||||||||||||||||||||||||||||||||-||||||||||||||||||  1 [I] COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase
-------------||||||||||||||||||||||||||||||||||||-|||------||-|---  1 [G] COG0205 6-phosphofructokinase
||||||||||------||||||--||||||||||||||-|||||||||||||||||||||||||||  1 [D] COG0206 Cell division GTPase
|||-----||---|||----||----||||||||||||-|||||||||||||||||---|||||--  1 [F] COG0207 Thymidylate synthase
---|-------|-||||-|-|||||-||||||||||||-|||||||||||||||||||||-|-|||  1 [F] COG0208 Ribonucleotide reductase, beta subunit
|-|||||||-|||||||||-|||||-||||||||||||-|||||||||||||||||||||||||||  1 [F] COG0209 Ribonucleotide reductase, alpha subunit
|-||||-------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0210 Superfamily I DNA and RNA helicases
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0211 Ribosomal protein L27
|--|-----||||||-|-|||||||-||||||-|||||--|||||||-||||||||||||||||||  1 [H] COG0212 5-formyltetrahydrofolate cyclo-ligase
-||---|||--------|---|-----||-||-||||||||||||-|-|------|---||-|---  1 [F] COG0213 Thymidine phosphorylase
|||||||||||||||--|--||----|||||--|||||------------||--------------  1 [H] COG0214 Pyridoxine biosynthesis enzyme
--|||||||-||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0215 Cysteinyl-tRNA synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0216 Protein chain release factor A
-|||--||||---|--||--|---------||||||||||||||||||||||||||||||||||||  1 [R] COG0218 Predicted GTPase
-------------||||||||||||-||||||||||||||||||||||||||||||||||||||||  1 [R] COG0220 Predicted S-adenosylmethionine-dependent methyltransferase
|-||||||-|-||||||-||||||--|||||----|-|||||||||||||||||||||||||||||  1 [C] COG0221 Inorganic pyrophosphatase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0222 Ribosomal protein L7/L12
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0223 Methionyl-tRNA formyltransferase
|-||-------|-||---||||--|-|||||||||||||||||||||-||||||||||||||||--  1 [O] COG0225 Peptide methionine sulfoxide reductase
||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||--  1 [P] COG0226 ABC-type phosphate transport system, periplasmic component
-------------||-|||||||||||||-|||||||||||||||||||||||||||||-||||||  1 [J] COG0227 Ribosomal protein L28
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0228 Ribosomal protein S16
|-||---------||---||||--|-|||-||||||||-||||||||-||||||||||||||||--  1 [O] COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase
-------------||-||||-||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0230 Ribosomal protein L34
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)
------------------|--|----||||-----|------|||||-||||---|---|||||||  1 [F] COG0232 dGTP triphosphohydrolase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0233 Ribosome recycling factor
--|----------||-||||||||||||||||||||||--||||||||||||||||||||||||||  1 [O] COG0234 Co-chaperonin GroES (HSP10)
||||||||||||||||||||||||||||||||||||||-|||||||||||||||||||||||||||  1 [H] COG0237 Dephospho-CoA kinase
-------------||-|||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0238 Ribosomal protein S18
|-------|----|||||||||||||||||||||||||||--|||||-||||||||||||||||||  1 [C] COG0240 Glycerol-3-phosphate dehydrogenase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0242 N-formylmethionyl-tRNA deformylase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0244 Ribosomal protein L10
----------------|||||||||-|||||----|||--||||||||||||||||||||||||--  1 [I] COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
--||-|-------|||||||||||||----|||-||||----||||||||||||||---|||||||  1 [L] COG0249 Mismatch repair ATPase (MutS family)
|||||||||||||-|-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0250 Transcription antiterminator
---|--||--|||||-||||||----||||||||||||----||||||||||||||||||||||--  1 [J] COG0251 Putative translation initiation inhibitor, yjgF family
|||||||||||||||-----||----||||||||||||----|||||-|||-||||||||-|----  1 [EJ] COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D
||------||------|||||-||--|||||---||||----||||||||||||||||||||||||  1 [E] COG0253 Diaminopimelate epimerase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0254 Ribosomal protein L31
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0255 Ribosomal protein L29
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0256 Ribosomal protein L18
-------------||-||||-||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0257 Ribosomal protein L36
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0261 Ribosomal protein L21
--|----------||-||||-|--|-||||||||-|||----|||||-||||||||--||||||--  1 [E] COG0263 Glutamate 5-kinase
--------------|-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0264 Translation elongation factor Ts
------------------||-|----||||-||||||||||||||||-||||||||---|||||-|  1 [L] COG0266 Formamidopyrimidine-DNA glycosylase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0268 Ribosomal protein S20
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0272 NAD-dependent DNA ligase (contains BRCT domain type II)
|--|||----|-|---||||-|--|-|||||||||||||||||||||-|-||-------||-|---  1 [F] COG0274 Deoxyribose-phosphate aldolase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [M] COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis
----||-------||-|-||-|||--||||-|-|||||----|||||-||||||||||||||||||  1 [H] COG0276 Protoheme ferro-lyase (ferrochelatase)
--|||||||-|||||--|||-|----|||-|||-||||----|||||-||||||||--||||||||  1 [C] COG0281 Malic enzyme
---------------||||||||||||||||||||||||||||||||-||||||||---|||||||  1 [F] COG0283 Cytidylate kinase
|||||||||||||||-||||||----||||||||||||----||||||||||||||||||||||--  1 [F] COG0284 Orotidine-5'-phosphate decarboxylase
---|||-------||-||||||--|-||||||||||||----||||||||||||||||||||||||  1 [H] COG0285 Folylpolyglutamate synthase
||||||--|||||||-||||-|----||||||-|||||----|||||-||||||||||||||||--  1 [E] COG0287 Prephenate dehydrogenase
|||-----||------||||--||--|||-||-|||||----||||||||||||||||||||||||  1 [E] COG0289 Dihydrodipicolinate reductase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0290 Translation initiation factor 3 (IF-3)
-------------|--||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0291 Ribosomal protein L35
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0292 Ribosomal protein L20
|||||||||||||||-||||||||--||||||||||||----|||||-||||||||||||||||-|  1 [H] COG0294 Dihydropteroate synthase and related enzymes
---|------|-|||--|---|---|-||||||||||||||||||||-|-||-------||-||--  1 [F] COG0295 Cytidine deaminase
--||||----|--||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN
|||||||||||||----|------|-----|||||||||||||||||-||||--------------  1 [H] COG0301 Thiamine biosynthesis ATP pyrophosphatase
----------||-||-|-||||----||||||||-|||----|||||-|||||--|||||||||||  1 [H] COG0302 GTP cyclohydrolase I
|||||||||||||---|-||-|----|||||---||||----|||||-||||---|||||||||--  1 [H] COG0303 Molybdopterin biosynthesis enzyme
-------------||-||||||||--||||||||||||----||||||||||||||||||||||||  1 [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0305 Replicative DNA helicase
||||----||--------||----------|----|----------|---|----------|----  1 [P] COG0310 ABC-type Co2+ transport system, permease component
|||||||||||||||--|---|----|||||--|||||------------||--------------  1 [H] COG0311 Predicted glutamine amidotransferase involved in pyridoxine biosynthesis
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [R] COG0313 Predicted methyltransferases
|||||||||-|||---|-||-|----|||-----||||----|||||-||||---|||||||||--  1 [H] COG0314 Molybdopterin converting factor, large subunit
|||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||--  1 [H] COG0315 Molybdenum cofactor biosynthesis enzyme
|-||||--|-|||||---||-|||--||||-||-||||----|||||-||||||||--||||||||  1 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [R] COG0319 Predicted metal-dependent hydrolase
--||---------|||||||||||||----||||||||----||||||||||||||---|||||||  1 [L] COG0323 DNA mismatch repair enzyme (predicted ATPase)
-------------||-||||||||||||||||||||||----||||||||||||||||||||||||  1 [J] COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase
--|----------||-||||||----||||||||||||----||||||||||||||||||||||--  1 [R] COG0325 Predicted enzyme with a TIM-barrel fold
-------------|||--|||---|||||||----|||----|||||||||||--||||-|-|-||  1 [O] COG0326 Molecular chaperone, HSP90 family
---|------|--||---||-|--|-||||----||||----|||||-||||||||||||||||||  1 [L] COG0328 Ribonuclease HI
|||||||||||||---|||||-||--||||||||||||----||||||||||||||||||||||||  1 [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase
-------------||-||||||||--||||||||||||----|||||-||||||||||||||||||  1 [I] COG0331 (acyl-carrier-protein) S-malonyltransferase
----------------|-||||||---||-||||||||----|||||-||||||||||||||||||  1 [I] COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III
--|||||||-|||||--|||||||--|---|--|||||----|||||--|||-|||||--||-|--  1 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0335 Ribosomal protein L19
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0336 tRNA-(guanine-N1)-methyltransferase
----||-|--|||||--|||||||--||||||||||||----||||||||||||||||||||||--  1 [E] COG0337 3-dehydroquinate synthetase
-|--|||-----------|||---|-----|----|-|----|||||-|-||||--||-------|  1 [L] COG0338 Site-specific DNA methylase
||||--|||--|-||-|||||||||-||||||||||||----|||||-||||||||||||||||||  1 [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase
||||--||-|------|||||||||||||||---||||-|--|||||-||||||||||||||||||  1 [U] COG0341 Preprotein translocase subunit SecF
||||--||-|------|||||||||||||||---||||-|--|||||-||||||||||||||||||  1 [U] COG0342 Preprotein translocase subunit SecD
|||||||||||||-||||||||||-||---||||||||----||||||||||||||||||||||||  1 [J] COG0343 Queuine/archaeosine tRNA-ribosyltransferase
----------------||||||--------|||||||||||||||||-||||-|||||||||||--  1 [S] COG0344 Predicted membrane protein
|||-----||------||||-|----|||-||---||-----|||||-||||||||---|||||--  1 [E] COG0347 Nitrogen regulatory protein PII
--|-|||||----||-|-||||----||||||-|||||----|||||-||||||||||||||||--  1 [H] COG0352 Thiamine monophosphate synthase
----------------|-|||||||-||||||||||||||--|||||-||||||||||||||||||  1 [L] COG0353 Recombinational DNA repair protein (RecF pathway)
--|----------|--|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0356 F0F1-type ATP synthase, subunit a
----------------||||||--|||||||||||||||||||||||-||||||||||||||||||  1 [M] COG0357 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division
|||||||||||||---||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0358 DNA primase (bacterial type)
--------------|-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0359 Ribosomal protein L9
-------------||-|||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0360 Ribosomal protein S6
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0361 Translation initiation factor 1 (IF-1)
-------------|||-|||--||||||||-|-||||-----|||||||-||-||----||||---  1 [G] COG0362 6-phosphogluconate dehydrogenase
-------------|||||||-||||||||--|-||||-----||||||||||||||||-|||||--  1 [G] COG0364 Glucose-6-phosphate 1-dehydrogenase
|||||||||||-||||----------||||||---|||----|||||-||--|-------|-|---  1 [E] COG0367 Asparagine synthase (glutamine-hydrolyzing)
|||||||||||||-----||||----|||-|----|-|----|||-|-||-----|---||||---  1 [H] COG0368 Cobalamin-5-phosphate synthase
|||---|||||-----||||-|--------||--||------|||||-||--|--||||----|--  1 [P] COG0370 Fe2+ transport system protein B
|||||||||||||-|--|||----------||||-|||----|||||-------------|-----  1 [C] COG0371 Glycerol dehydrogenase and related enzymes
|-||||--|-|||||-||||-|----||||-|--||||----|||||-||-|||||||||||||||  1 [C] COG0372 Citrate synthase
||||||--|||||---|-||||||--|||||---||||----|||||-||-||||||||-------  1 [H] COG0373 Glutamyl-tRNA reductase
||||--||||||----|||||-----|||||----|||----|||||-||--||||||-||-||--  1 [H] COG0379 Quinolinate synthase
||-|--||---------|||-|--------||-||||-----|||||-||-|-|||--|-----||  1 [M] COG0381 UDP-N-acetylglucosamine 2-epimerase
--||---------||---||||----|||-|----|||----|||-|-||-|---|---|||||--  1 [R] COG0384 Predicted epimerase, PhzC/PhzF homolog
-------------|||--|-|-----|---|||||||||---|||||--|--||||-------|--  1 [O] COG0386 Glutathione peroxidase
||||----||---|--||||-|----||||||||||||----|||||-|--|--------------  1 [S] COG0391 Uncharacterized conserved protein
|||||||||--|-----|||-------|||-|---|-|----|||-|-|--|-----------|--  1 [S] COG0393 Uncharacterized conserved protein
|||||||||||||----|||-||||-||||||||||||----|||||-----|------|||||--  1 [O] COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
--||---------||---||------|||-||||||||----|||---|-----------|--|--  1 [S] COG0398 Uncharacterized conserved protein
---|||||---||||-||||-|-----|||----||||----|||||--|--|-||---|||||--  1 [E] COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain
---|||||---||||-||||-|-----|||----||||----|||||--|--||||---|||||--  1 [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase)
--|-||-------||-|-||-|||--||||----||||----|||||-||-|||||||||||||||  1 [H] COG0407 Uroporphyrinogen-III decarboxylase
---|--||--|||||-||||-|----|||||---||||----||||||||--||||||||||||--  1 [H] COG0413 Ketopantoate hydroxymethyltransferase
-------------||-||||-|----|||||---||||----||||||||--||||||||||||--  1 [H] COG0414 Panthothenate synthetase
|-||-------|-|----||------|-----|-||------||||||||----|----|--||--  1 [L] COG0415 Deoxyribodipyrimidine photolyase
----------------||||||||------|||||||||||||||||-||-|-|||||||||||--  1 [I] COG0416 Fatty acid/phospholipid biosynthesis enzyme
||||||||||||||||||||||--||----||--|||-----|||||-||----------------  1 [L] COG0419 ATPase involved in DNA repair
||||--||--||||||||-|-|---||||------|------|||-|--|---|||--|-|-----  1 [P] COG0428 Predicted divalent heavy-metal cations transporter
---|---------||---||-|----|||--|||||||--|||||||-||-|-|||---||-||--  1 [R] COG0431 Predicted flavoprotein
|||-----|--|-||-|-||-||||--||-||||||||----|||||-||||||||||||||||--  1 [I] COG0439 Biotin carboxylase
|||---||||--|||-||||-|----||||||-|||||----||||||||||-|||--||||||--  1 [E] COG0440 Acetolactate synthase, small (regulatory) subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0441 Threonyl-tRNA synthetase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0442 Prolyl-tRNA synthetase
|-||||-------|||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0443 Molecular chaperone
--|||||||-|||---||--||||-||---|||||||||||||||||-||||---||||||||---  1 [EP] COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
-------------||-||||||||||----||||||||||||||||||||||||||||||||||||  1 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division
---|----|---------||------||||-|--|||-----|||||-|-||--------------  1 [H] COG0447 Dihydroxynaphthoic acid synthase
|||-|||||-|||||||||||||||--|||-||-||||----||||||||-||--|||||||||||  1 [O] COG0450 Peroxiredoxin
||||||||||||-||-||||||---|||||||-|||||----|||||-||||||||||||||||--  1 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases
|||||||||||||||-||||||---|||||||||||||----|||||-||||||||||||||||--  1 [H] COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase
||||||--||||-||-||||||----||||||||||||----||||||||-|||||||||||||--  1 [EF] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
||||||||||||||||||||||||||||||||||||||--||||||||||||||||||||||||||  1 [O] COG0459 Chaperonin GroEL (HSP60 family)
|||||||||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1 [E] COG0460 Homoserine dehydrogenase
|||||||||||||||-||||||-|--||||||||||||----||||||||||||||||||||||--  1 [F] COG0461 Orotate phosphoribosyltransferase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0465 ATP-dependent Zn proteases
|||||||||||||||||||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG0468 RecA/RadA recombinase
-|||||||--||||||-|||||||-|||||||||||||||||||||||||||||||--||||||--  1 [G] COG0469 Pyruvate kinase
|||||||||||||||||||||||||-||||-|||||||||||||||||||||||||||||||||||  1 [L] COG0470 ATPase involved in DNA replication
|||---||||||-||-||||-|----||||||--||||----||||||||||||||--||||||||  1 [CE] COG0473 Isocitrate/isopropylmalate dehydrogenase
|||-|||||-|||||-|-||-|---|-|||||--||||----|||||-|||-||||||||||||||  1 [P] COG0475 Kef-type K+ transport systems, membrane components
|-|||||||-|||||||-||||----|||||--|||||----|||||-||||||||||||||||--  1 [H] COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0480 Translation elongation factors (GTPases)
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [M] COG0481 Membrane GTPase LepA
-------------||-||||||||-|||||||||||||||||||||||||||||||||||||||||  1 [J] COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain
||||--||||||||--||||-|---|||||-|||||||----|-||||||||||||--||||||||  1 [G] COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family
|-||||-------|||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain
-------------||-||||||||||----||||||||||||||||||||||||||||||||||||  1 [R] COG0486 Predicted GTPase
||||||||||||||||||||||----|||||--|||||----|||||-||||||||||||||||||  1 [D] COG0489 ATPases involved in chromosome partitioning
--|-||||--|-|||||||--|--|-||||||--||||----|||||-||--|--|--||||||||  1 [ER] COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0495 Leucyl-tRNA synthetase
----------------|-||||--|-||||||||||||----|||||-||||||||||||||||||  1 [L] COG0497 ATPase involved in DNA repair
|||||||||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1 [E] COG0498 Threonine synthase
|||||||||||||||||-||||----|||||-||-|||----||||||||||||||||||||||--  1 [O] COG0501 Zn-dependent protease with chaperone function
||||||||||||||||||||-|||||||||||||||||||--||||||||||||||||||||||||  1 [F] COG0504 CTP synthase (UTP-ammonia lyase)
||||||--||||-||-||||||----||||||||||||----||||||||-|||||||||||||--  1 [EF] COG0505 Carbamoylphosphate synthase small subunit
-|-----------||----|-|||-|-||-||||||||-|--|||||||||||||---|||||---  1 [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member
---|||||---||||-||||-|||---|||--|-||||-|--|||||-||--||||---|||||--  1 [E] COG0509 Glycine cleavage system H protein (lipoate-binding)
-------------||-----|---|------|||||||-||||||||-|-|-----------|---  1 [M] COG0510 Predicted choline kinase involved in LPS biosynthesis
|||---|||--|-||-|||||||||-||||||||||||----|||||-||||||||||||||||--  1 [I] COG0511 Biotin carboxyl carrier protein
|||||||||||||||-||||||-|-|||||||||||||----|||||-||||||||||||||||--  1 [F] COG0519 GMP synthase, PP-ATPase domain/subunit
|-||--||-|-||-|--||||||||||||||||||||||||||||||-|||||--|||||||||--  1 [E] COG0520 Selenocysteine lyase
|||||||||||||---|--|-|----|||||---||||----|||||-||||---|||||||||--  1 [H] COG0521 Molybdopterin biosynthesis enzymes
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0522 Ribosomal protein S4 and related proteins
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0525 Valyl-tRNA synthetase
|||||||||||||---||||||||||||||||||||||||||||||||||||||||||||||||||  1 [F] COG0528 Uridylate kinase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0532 Translation initiation factor 2 (IF-2; GTPase)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0533 Metal-dependent proteases with possible chaperone activity
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [R] COG0536 Predicted GTPase
|||||||||-|||||||-||||||-|||||||||||||||||||||||||||||||||||||||||  1 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
---|||--|-|||||-||||-|-----||--|--||||----|||||--|-|---|||-|||||--  1 [C] COG0538 Isocitrate dehydrogenases
-------------||-||||||||||||||||||||||-|--||||||||||||||||||||||||  1 [J] COG0539 Ribosomal protein S1
|||||||||||||||-||||||----||||||||||||----||||||||--||||||||||||--  1 [F] COG0540 Aspartate carbamoyltransferase, catalytic chain
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0541 Signal recognition particle GTPase
|||-||||||-|-||-||--|---|-|||-||-|-|||----|||||-||---|||---|----||  1 [HC] COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)
||||||-||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1 [E] COG0547 Anthranilate phosphoribosyltransferase
|||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||-|  1 [E] COG0548 Acetylglutamate kinase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0550 Topoisomerase IA
|||||||||--------|--|-|||-----|||||||||-|||||||||||||||||||-------  1 [L] COG0551 Zn-finger domain associated with topoisomerase type I
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0552 Signal recognition particle GTPase
---|||-||--|||--||||||---|||||||||||||-||||||||-|||||--|---|||||--  1 [C] COG0554 Glycerol kinase
|-||------------|||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG0556 Helicase subunit of the DNA excision repair complex
---|---------||||||||||||-|---||||||||||||||||||||||||||||||||||--  1 [K] COG0557 Exoribonuclease R
|-|||||||-|||||||||||-|||||||||||||||||||||||||-||||||||||||||||||  1 [I] COG0558 Phosphatidylglycerophosphate synthase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)
||||--|||||-|---||||||--||-||---||||||-||||||||-||||-||---||||----  1 [P] COG0569 K+ transport systems, NAD-binding component
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0571 dsRNA-specific ribonuclease
---|---------||--|||-|-|||----|||||||||-|||||||-|-||--------------  1 [F] COG0572 Uridine kinase
||||---||||||---||||-|---||||||||||||||-|||||||-|-|||--|--||||||--  1 [P] COG0573 ABC-type phosphate transport system, permease component
|||||||||||||||||||||||||||||||||||||||||||||||-||||||||||||||||||  1 [I] COG0575 CDP-diglyceride synthetase
|-||||-------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0576 Molecular chaperone GrpE (heat shock protein)
---|||-----|-|||--|--|---|||||-|||||||----|||||-|||||--|---||||---  1 [C] COG0578 Glycerol-3-phosphate dehydrogenase
||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||--  1 [P] COG0581 ABC-type phosphate transport system, permease component
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0587 DNA polymerase III, alpha subunit
--|----------||-----|-||||||||||||||------||||||--||||||----||||--  1 [G] COG0588 Phosphoglycerate mutase 1
--|----------||||-||-|||--||||||-|||||----||||||||||||||---|||||||  1 [FJ] COG0590 Cytosine/adenosine deaminases
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)
----------------||||-|||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0593 ATPase involved in DNA replication initiation
-----------------||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0594 RNase P protein component
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [MU] COG0597 Lipoprotein signal peptidase
|||-||--||-|-||--||--|----|||--|---|||-------|---||-||||---|||||--  1 [S] COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit
||||||||||||----|-|||---------||||||||----|||||-||||||||||||||||||  1 [O] COG0602 Organic radical activating enzymes
|-||||----|||||||-||-|||-|||||||||||||----||||||||||||||||||||||||  1 [P] COG0605 Superoxide dismutase
||||||||||||----|||||||||||---||||||||----|||||-||||||||||||||||||  1 [L] COG0608 Single-stranded DNA-specific exonuclease
||||---||----------|-----------||-||--|||-------||||||--|||-||-|-|  1 [V] COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
|||||||||||||||||--------------|--|||----------------------------|  1 [MI] COG0615 Cytidylyltransferase
|||||||||-|-|---|||||||||-||||-----|||----||||||||||||||||||||||||  1 [OU] COG0616 Periplasmic serine proteases (ClpP class)
-------------|||||||||||||||||||||||||----||||||||||||||||||||||||  1 [J] COG0617 tRNA nucleotidyltransferase/poly(A) polymerase
-|||--|||||-|---||||||--|||||-||||||||||||------|-----------------  1 [R] COG0618 Exopolyphosphatase-related proteins
||||--|||||||||--|--|---|----|||||||||-||||||||-||----------------  1 [R] COG0622 Predicted phosphoesterase
----------------|-||-|||---|||-|--||||----|||-||-|||-|||||||||||||  1 [I] COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH)
-------------|----||------||||-|||||------|||||--|||-|||---|||||--  1 [R] COG0627 Predicted esterase
-----|-------||-|-||-|||--||||||||||||||||-------|--|--||--|--|---  1 [T] COG0631 Serine/threonine protein phosphatase
-----------------||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG0632 Holliday junction resolvasome, DNA-binding subunit
----------------||--||----||||||-|||||||||||||||||||||||---|||||--  1 [F] COG0634 Hypoxanthine-guanine phosphoribosyltransferase
----------------|||||||||||||-|||||||||---||||||||||||||||||||||||  1 [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases
-|||||||||||||||-|||||--------||-|-|||----||||||||||||||--|||-||--  1 [T] COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases
--||--|||--------|||-|--||----|----|||----|||||-||--|--||||||-||--  1 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases
-----------------|||||----|||||---||||----|||||-||-----|---|||||--  1 [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain
---|--|||--||||-||--|-----|||--|||||||----|||||--|--------||||||||  1 [G] COG0647 Predicted sugar phosphatases of the HAD superfamily
||||||||--||||||||----||---||||---|||||||||||||||-----------------  1 [L] COG0648 Endonuclease IV
||||-||||-|||----|||-|----|||-----||||----|||-|-||---------|||--||  1 [CP] COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit
|-||---------|||--||||--|-||||||||||||----|||||-||||||||||||||||--  1 [O] COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
|||-----||-|-||-|---||-----||||--|||||----||-||-||--|--|---|||-|-|  1 [R] COG0655 Multimeric flavodoxin WrbA
--|--|--|--|-||--|||-|--|-|||||||-||-|----|||||-||--|--|---||-||--  1 [I] COG0657 Esterase/lipase
----------------|||||||||||||-|||||||||||||||||-||||||||||||||||-|  1 [R] COG0658 Predicted membrane metal-binding protein
--|||||||-|||||-|-||-|||-|||||||||-|||----|||||-||||||||||||||||--  1 [E] COG0665 Glycine/D-amino acid oxidases (deaminating)
|||||||||||||-||||||||--|||||-||||||||----||||||||--||||||||||||||  1 [M] COG0668 Small-conductance mechanosensitive channel
----------------||||||--||||||||||||||-|--||||||||||||||||||||||--  1 [H] COG0669 Phosphopantetheine adenylyltransferase
-------------||---||||||-|----|||||||--|--|||||-||||-|||||||||||||  1 [R] COG0670 Integral membrane protein, interacts with FtsH
--------|---|||--||||---|---------|||-----||||---|-|-||---|--|--||  1 [P] COG0672 High-affinity Fe2+/Pb2+ permease
|||||||||||||||-|||||---|--||-||--||-|----|||||-|-------|||-------  1 [C] COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit
||-------|---||-|||||-----|---||--||||----||||--||-||--|--||||||||  1 [R] COG0679 Predicted permeases
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [M] COG0682 Prolipoprotein diacylglyceryltransferase
--|-||||--|||||-||||-|----|---||-|||||----||||||||||||||--||||||--  1 [E] COG0685 5,10-methylenetetrahydrofolate reductase
------------------||-|-----|||-|--||||----------|-------||--|-||--  1 [E] COG0686 Alanine dehydrogenase
---|----|-|-|----|||||--||----||||||--|||||||||-||||-|||---|||||--  1 [E] COG0687 Spermidine/putrescine-binding periplasmic protein
|---|||||||||||||--|||----||||-----|||----|||||-||||||||---|||||||  1 [J] COG0689 RNase PH
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0690 Preprotein translocase subunit SecE
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0691 tmRNA-binding protein
---|----|----||---||--||----------||||----|||||||||||---||||||||||  1 [O] COG0694 Thioredoxin-like proteins and domains
|-||----|----|||-|||-|----|||||||||||-----|||||-||||||||---|||||||  1 [O] COG0695 Glutaredoxin and related proteins
--||-----------|--||----------|---|||||||||||||-||------||||------  1 [G] COG0696 Phosphoglyceromutase
|-|||||||-|||||||||||||||-|||-||-|||||----||||||||||||||||||||||||  1 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily
|||-----||------||||-------||-|-||-|||----|||-------------|-------  1 [R] COG0701 Predicted permeases
--|----------||-||||||||--||||||||||||----||||||||||||||||||||||--  1 [E] COG0703 Shikimate kinase
|||||||||||||---||||-|---|||||||||||-||-|||||||-||--|--|---|||||--  1 [P] COG0704 Phosphate uptake regulator
-||||-|||||||||-||||-|--|-||||||||||||----|||||-|||||--|--||||||--  1 [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid)
--|------|-|----||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase
|-|-||--|--|-|||--||||--|||||-||||-||-----|||||-||||||||||||||||||  1 [L] COG0708 Exonuclease III
||||||-|||||-||-|-----||-------||||||-----|||-|------||-----------  1 [E] COG0710 3-dehydroquinate dehydratase
--|-------------|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0711 F0F1-type ATP synthase, subunit b
-------------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0712 F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)
|||||||||||||---||||-|---||||||---||||----|||||-||--|--|---|||||--  1 [R] COG0714 MoxR-like ATPases
-----------------|||||||-|||||||||||||||||||||||||||||||||||||||||  1 [S] COG0718 Uncharacterized protein conserved in bacteria
||||----||-||---||||||||||||||||||||||--||-------|---|||||||||||||  1 [J] COG0721 Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit
|||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||--  1 [P] COG0725 ABC-type molybdate transport system, periplasmic component
--|--|-|-|---|||-|||||||---|||||||||||----|||||-||--|--|||-|||||--  1 [G] COG0726 Predicted xylanase/chitin deacetylase
-|||--|||-------|---|-|||-|------|||||----------|-||-||-|||-------  1 [R] COG0733 Na+-dependent transporters of the SNF family
-------------||-||--|||||||||||||||||||||||||||||----|||||||||||||  1 [I] COG0736 Phosphopantetheinyl transferase (holo-ACP synthase)
----------------||||----||----||||-|||----||||||||||||||||||||||||  1 [M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)
-----------------|||||||||||||||||||||-|--||||||||||||||||||||||||  1 [L] COG0742 N6-adenine-specific methylase
----------------|||||||||-|||||----|||----|||||||||||||||||||--|--  1 [I] COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase
|||||||||||||---|-||-|----|||-----||||----|||||-||||--||||||||||--  1 [H] COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A
--|||||||-|||---||||||||--|||||||-||||----|||||-||||---||||||||---  1 [E] COG0747 ABC-type dipeptide transport system, periplasmic component
-------------|--||||||||||||||||||||||----|||||-||||||||||||||||||  1 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains
|||||||||||||---||||||||||||||||||||||----|||||-||||||||||||||||||  1 [M] COG0750 Predicted membrane-associated Zn-dependent proteases 1
----------------|||||-||-------|||-|||----||||||||||||||||||||||||  1 [J] COG0751 Glycyl-tRNA synthetase, beta subunit
----------------|||||-||-------|||-|||----||||||||||||||||||||||||  1 [J] COG0752 Glycyl-tRNA synthetase, alpha subunit
-------------||------|----|-------||||----|||||-||||-||||||||||---  1 [P] COG0753 Catalase
-------------||||---|-|||-||||||||-||-----||||||-|||||||||-|||||||  1 [F] COG0756 dUTPase
----------------||||||--|||||-|-||||||||--|||||-||||||||||||||||-|  1 [LU] COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake
----------------||||||||||-||-||||||||----|---|-|||||||||||||||||-  1 [S] COG0759 Uncharacterized conserved protein
-----------------||||-||||||||||||||||----|||||-||||---||||||-||--  1 [S] COG0762 Predicted integral membrane protein
----------------||||||||------||||||||----||||||||||||||||||||||||  1 [I] COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases
|--------|------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0769 UDP-N-acetylmuramyl tripeptide synthase
|||------|------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase
|--------|------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0773 UDP-N-acetylmuramate-alanine ligase
--|--------------|--|||||||||-||||||||||--||||||||||-|||||||||||--  1 [F] COG0775 Nucleoside phosphorylase
----||----------||||||||||-|||||||||||||||||||||||||||||||||||||||  1 [L] COG0776 Bacterial nucleoid DNA-binding protein
----------------|-||||||--|||-||||||||----|||||-||||||||||||||||--  1 [I] COG0777 Acetyl-CoA carboxylase beta subunit
----------------||||||--|||||-||||||||----|||||-||||||||||||||||||  1 [S] COG0779 Uncharacterized protein conserved in bacteria
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0781 Transcription termination factor
-----------------|---|||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0782 Transcription elongation factor
---|--------------||||--|||----|||||||-|--|||||-|||||--|||||-|-|||  1 [P] COG0783 DNA-binding ferritin-like protein (oxidative damage protectant)
--------------|-|-||||--||||||||||||||----|||||-||||||||||||||||||  1 [M] COG0787 Alanine racemase
----||----||----||||||||||----|---||||----|||||-||||||||||||||||||  1 [M] COG0793 Periplasmic protease
|||---|||||||---|---|-||------|---|||-----|||||-||||||||||||||||||  1 [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation
----------------|-||||--||||||||||||||----||||||||||-|||||||||||--  1 [M] COG0796 Glutamate racemase
----------------||||-|||||||||-|||||||----|||||-||||||||||||||||||  1 [S] COG0799 Uncharacterized homolog of plant Iojap protein
-------------||-||||||||--||||||||||||----|||||-||||||||||||||||-|  1 [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase
----------------||||||||||||||||||||||-|--|||||-||||||||||||||||||  1 [R] COG0802 Predicted ATPase or kinase
--||||--|-|||---|-||-|----||||----||||----|||||-||||||||||||||||||  1 [U] COG0805 Sec-independent protein secretion pathway component TatC
----------------||||||--||||||||||||||----||||||||||||||||||||||||  1 [J] COG0806 RimM protein, required for 16S rRNA processing
----------------||||||---|----||||||||----||||||||||||||||||||||||  1 [J] COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0812 UDP-N-acetylmuramate dehydrogenase
-----------|--------||--|------||||||-|||||||||||-||----||----|---  1 [F] COG0813 Purine-nucleoside phosphorylase
----------------||||||||--|||||||-||||||||||||||||||||||||||||||||  1 [L] COG0816 Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis)
-----------------|||-|--------||||||||----|||||-|||||||||||||||---  1 [M] COG0818 Diacylglycerol kinase
----||||--|||||----|------|----|-|||||------------||----|||--|----  1 [K] COG0819 Putative transcription activator
----------------||||||--|-|||-|||||||||---||||||||||||||||||||||--  1 [R] COG0820 Predicted Fe-S-cluster redox enzyme
--||----|----|||||-||-||||||||||||||||||||||||||||||-|||||||||||||  1 [C] COG0822 NifU homolog involved in Fe-S cluster formation
|-||||----|||---|-||||--|-|||-|---||||----|||||-||||||||||||||||--  1 [R] COG0824 Predicted thioesterase
----------------|-||||||--|||-||||||||----|||||-||||||||||||||||--  1 [I] COG0825 Acetyl-CoA carboxylase alpha subunit
----------------|-||--||||----|||||||||-||||||||||||||||||||||||||  1 [J] COG0828 Ribosomal protein S21
-------------||---------------||--|||-----|||||--|-----|||--------  1 [E] COG0833 Amino acid transporters
--||--|||--------|||----||----|----|||----|||||-||--|--||||||-||--  1 [NT] COG0835 Chemotaxis signal transduction protein
---|------||||--|-||-|----||||----||||----||||||-|--|--|---|||||||  1 [C] COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1
------||||||||||||--||----|||||-|-||||-|--|||||-||-|---||||----|--  1 [K] COG0846 NAD-dependent protein deacetylases, SIR2 family
----|---|----||||||--||||-|||-||||||||----||||||||||||||||||||||||  1 [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
---------|------||--||--||----||||||||----||||||||||||||||||||||||  1 [D] COG0849 Actin-like ATPase involved in cell division
----------------||||||--------|----|||----||||||||-|||||||-||||---  1 [D] COG0850 Septum formation inhibitor
----------------||||-|----|||||---||||----|||||--|--||||||||--||--  1 [H] COG0853 Aspartate 1-decarboxylase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0858 Ribosome-binding factor A
||||--|||||||-----------------|----|||----|||-|---------||---|-|--  1 [K] COG0864 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain
|||-----||-----------|---|----|----|||----|||--------------||||---  1 [F] COG1001 Adenine deaminase
---|||||---||||-||||-|-----|||----||||----|||||--|--|-||---|||||--  1 [E] COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain
||||--||---------|||-|----|-------||||----------||---------|||--||  1 [P] COG1006 Multisubunit Na+/H+ antiporter, MnhC subunit
--||||-||-|||---|-||-|----|||-----||||----||||||||--||||||||||||||  1 [CP] COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit
||||||--||||------|||------||-|----|----------|--|-----|---||||---  1 [H] COG1010 Precorrin-3B methylase
|||||||||||||||-|||||---|--||-||--||-|----|||||-|-------|||-------  1 [C] COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit
|||||||||||||---|||||---|--||-||--||-|----|||||-|------||||---||--  1 [C] COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit
-----------------|---|--------||||||||-|--|||||||-------||-||-|---  1 [G] COG1015 Phosphopentomutase
-------------||----|------||||-||||||-----|||||-||-----|--||-||---  1 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins
-------------||-----------|||-||--||||---------------------||||---  1 [C] COG1038 Pyruvate carboxylase
----------------|-----||-------||||||-||||------------------------  1 [L] COG1039 Ribonuclease HIII
--||----------|--|||------||||||||||||----||||||||||-|||||||||||--  1 [E] COG1045 Serine acetyltransferase
--||||----|||||-|----|----||||||--|||-----|||||-||--||||---|||||||  1 [C] COG1048 Aconitase A
----||||--|||||-|-|||---|-----|-|-||||----|||||-||||-|||||||||||--  1 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases
||-|||--|||||||-||||||||--||||||--||||----|||||-||||||||||||||||||  1 [C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit
------------------||-|||--|----||||||-----||||||||--|--|---|||||||  1 [R] COG1054 Predicted sulfurtransferase
----|||||-|||----||||-||---|||----||||----||||--||---|||--||--|---  1 [P] COG1055 Na+/H+ antiporter NhaD and related arsenite permeases
-------------||-|||||---||||||||||||||||||||||||||--||||||||||||--  1 [H] COG1057 Nicotinic acid mononucleotide adenylyltransferase
---||||||-||||---|||||-----||||-||||||----|||||-|----|||---|||||--  1 [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA
--|||||||-||||||---|||--|-|||||-||||------|||||-|-----------------  1 [KL] COG1061 DNA or RNA helicases of superfamily II
----------------|||||||||-|||-|||-||||----|||||-||||||||||||||||||  1 [O] COG1066 Predicted ATP-dependent serine protease
-----|-------||-----------||||-|||-|||----|||||-|-||-------||||---  1 [H] COG1072 Panthothenate kinase
--------------------|-||||-||-||||||||----||||||||||||||||||||||||  1 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)
|||||||||||||--|||--|----------||||||||-||------------------------  1 [R] COG1078 HD superfamily phosphohydrolases
---|--|||-|-|----|-|-|--||----||||-||-||||-------|-----|---||||---  1 [R] COG1079 Uncharacterized ABC-type transport system, permease component
--------------------||||-||---||||||||-|||||||||||||||||------||--  1 [G] COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)
|------------||-|-||||----|---||-|-|||--|||||||-||||-|||||||||||--  1 [M] COG1087 UDP-glucose 4-epimerase
----||------------||------||||----||||----|||||--||||-------------  1 [R] COG1090 Predicted nucleoside-diphosphate sugar epimerase
-|----||-|--|---||--||||-------||||||-----||||||||||||||---||||---  1 [R] COG1092 Predicted SAM-dependent methyltransferases
--------------------------|||||||-||||----|||||--|---------|-|----  1 [E] COG1113 Gamma-aminobutyrate permease and related permeases
--|----------||------|----||||-|--||||----|||||----|--------------  1 [P] COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA
--|-----|-------|-||------|||||||-||||--------|-||-||||---|-||||||  1 [GM] COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component
|--|---||-|-|----|||-------||-||||||||----------------------------  1 [C] COG1141 Ferredoxin
----------------|||||||||-||||||---|||----||||||||||||||||||||||--  1 [HI] COG1154 Deoxyxylulose-5-phosphate synthase
----------------||----||||----|----|||----||||||||-----|||||||||--  1 [NU] COG1157 Flagellar biosynthesis/type III secretory pathway ATPase
----------------||--|||||||||||---||||----||||||||||||||||||||||||  1 [K] COG1158 Transcription termination factor
----------------||||||--||||||||||||||||||||||||||||||||||||||||||  1 [R] COG1159 GTPase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [R] COG1160 Predicted GTPases
---|--------------||------||||-|--|||-----|||||-|-||--------------  1 [H] COG1165 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
----||||--|||||--|-|||----|||||-||||||----|||||-||-|---|---|||||--  1 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
--------------------||----||||||-|-|||----|||||---|----|----------  1 [E] COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
---|--------------||------||||-|--|||-----|||||-||||---------|----  1 [HQ] COG1169 Isochorismate synthase
---|||----|||||--|||||----||||-|-|||||----|||||-||||||||--||||||||  1 [E] COG1171 Threonine dehydratase
---|----|-|-|----|-|||--||----||||||--|||||||||-||||-|||---|||||--  1 [E] COG1176 ABC-type spermidine/putrescine transport system, permease component I
---|----|-|-|----|-|||--||----||||||--|||||||||-||||-|||--||||||--  1 [E] COG1177 ABC-type spermidine/putrescine transport system, permease component II
|||-|||||||||---||--|------||-||||||------|||||-||||---|----------  1 [O] COG1180 Pyruvate-formate lyase-activating enzyme
-------------||-||||||||||||||||||||||----||||||||||||||||||||||||  1 [J] COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)
-------------||-|||||||||||||||||-||||----||||||||||||||||||||||||  1 [J] COG1186 Protein chain release factor B
-----------------|--|-----|---||||||||----|||||-||||-|||||||||||--  1 [J] COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
--|-----|-------|||||----|||||||||-|||||----------------||||||||||  1 [J] COG1189 Predicted rRNA methylase
--|-------||-|||||||||||--|||||||||||||||||||||||||||||||||||-----  1 [J] COG1190 Lysyl-tRNA synthetase (class II)
----------------||||--|||--||-|---||||----|||||-||-----||||-------  1 [K] COG1191 DNA-directed RNA polymerase specialized sigma subunit
|-||--||--------||||||---|----||||||||------------------|||-------  1 [L] COG1193 Mismatch repair ATPase (MutS family)
|--|------|-|-|------||||-||||||||||||----||||||||||||||||||||||--  1 [L] COG1194 A/G-specific DNA glycosylase
----------|-------|||||-|-||||||||||||----|||||-|||||------|||||||  1 [L] COG1195 Recombinational DNA repair ATPase (RecF pathway)
-||||||||----|||||||||--||||||||||||||||||-------|--|||----|||||--  1 [D] COG1196 Chromosome segregation ATPases
-----------------|||||||||||||||||||||----||||||||||||||||||||||||  1 [LK] COG1197 Transcription-repair coupling factor (superfamily II helicase)
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1 [L] COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase
----------------||||||--||||||||||||||----|||||-||||||||||||||||||  1 [LK] COG1200 RecG-like helicase
----------------||||||---------|||||||---------------------|||||--  1 [J] COG1206 NAD(FAD)-utilizing enzyme possibly involved in translation
----------------||||||----||||||||||||----||||||||||||||||||||||||  1 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)
|||----|---|----|--||----|||||||||||||--|||||||-||||||||||||||||--  1 [M] COG1210 UDP-glucose pyrophosphorylase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone
|-|-||||||||-||||-||------|---|||-||||----|||||--|-----|---|||||-|  1 [M] COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
------------------||||----||||||||||||----||||||||||||||||||||||||  1 [T] COG1217 Predicted membrane GTPase involved in stress response
-------------|--||||||||||||||||||||||----||||||||||||||||||||||||  1 [O] COG1219 ATP-dependent protease Clp, ATPase subunit
----------------||-------|--------||||----|||||||||||--|||||||||||  1 [O] COG1220 ATP-dependent protease HslVU (ClpYQ), ATPase subunit
||||||||||-|||--||||-|----|||-||---|||||--|||||-|||-||||||||||||||  1 [P] COG1226 Kef-type K+ transport systems, predicted NAD-binding component
-|------|----|||-|--||--------|||||||-----------|-----------------  1 [C] COG1227 Inorganic pyrophosphatase/exopolyphosphatase
--|---|---||-|||||-|-|----|--||||||||-----|||||--|-|||||--||||||--  1 [P] COG1230 Co/Zn/Cd efflux system component
--||--|-|-|--||-|----|||--||||----||||-------|---------|-------|--  1 [H] COG1232 Protoporphyrinogen oxidase
||||-------||-----||-|----|||-----||-|-----------------|------||--  1 [Q] COG1233 Phytoene dehydrogenase and related proteins
-|-------|------||--|---------|||-||||----|||||-|-----------------  1 [R] COG1242 Predicted Fe-S oxidoreductase
--|-------|-|-----||-|----|---||-|||||----|||-|-||-----|---|||||--  1 [M] COG1247 Sortase and related acyltransferases
-||-|||||-|||----|-|-|---|--|-||||||||----|||||-||-|---|----|-|---  1 [C] COG1254 Acylphosphatases
----------------||------||----|----|||----||||||||-----|||||||||--  1 [N] COG1256 Flagellar hook-associated protein
||||||||||||||||---------|-----|||||------------|-----------------  1 [I] COG1257 Hydroxymethylglutaryl-CoA reductase
|||---||-||-|---|---|-----------|--|||----|||||-||||-||||||-----||  1 [I] COG1267 Phosphatidylglycerophosphatase A and related proteins
|-||--|||--------||||||-|-|---||||||||---------------------||||-||  1 [R] COG1268 Uncharacterized conserved protein
|||||||||||||-----||||-----||-|----|-|--------|-||-----|---||||---  1 [H] COG1270 Cobalamin biosynthesis protein CobD/CbiB
--||||--|-------|-||--||--|||--|--||||----|||||-||||---|--||||||||  1 [C] COG1271 Cytochrome bd-type quinol oxidase, subunit 1
-------------|||----||--|||||-||||||||----|||||-||--|||----|||||--  1 [R] COG1272 Predicted membrane protein, hemolysin III homolog
----------------|----|-------------|||----|||||--------|----|-|---  1 [P] COG1276 Putative copper export protein
----------------||||||--------||||||||-|--|||||-||||||||---|||||--  1 [O] COG1281 Disulfide bond chaperones of the HSP33 family
----------------|-||||--|--||-||-|-|||----|||||--|||---|---|||----  1 [S] COG1285 Uncharacterized membrane protein
------------------------||-----|||||||----|||||-||||||||||||||||||  1 [R] COG1286 Uncharacterized membrane protein, required for colicin V production
------------------|--|------------|||-----|||||-||||||||--|||||---  1 [S] COG1289 Predicted membrane protein
----------------||------||----|----|||----|||||-||-----|||||||||--  1 [N] COG1291 Flagellar motor component
---|--------------------|-|||-----||||----|||||-||||-||-----|-----  1 [M] COG1292 Choline-glycine betaine transporter
||||||||||||||||-|||||---|----||||||||------------------|||-------  1 [K] COG1293 Predicted RNA-binding protein homologous to eukaryotic snRNP
--||------------|-||--||--|||--|--||||----|||||-||||---|--||||||||  1 [C] COG1294 Cytochrome bd-type quinol oxidase, subunit 2
--|-------------|-||||||--||||||||||||-|--|||||-||||||||||||||||||  1 [S] COG1295 Predicted membrane protein
--|-----|-----------||----|----|-|||||----|||||-||||-|||||-||||---  1 [E] COG1296 Predicted branched-chain amino acid permease (azaleucine resistance)
----------------||----||||----|----|||----||||||||-----|||||||||--  1 [NU] COG1298 Flagellar biosynthesis pathway, component FlhA
|||||||||||||||---||-|--||||||-||||||-----|||||-||||-||----|||||||  1 [C] COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
----------------|-|||||||||||||||||||||-|-||||||||||||||||||||||||  1 [U] COG1314 Preprotein translocase subunit SecG
||||--||---------|---|----|-------||||----------||---------|||--||  1 [P] COG1320 Multisubunit Na+/H+ antiporter, MnhG subunit
|||||||||||||----|---||||-||||||||||||----|||-|-----|---------|---  1 [K] COG1321 Mn-dependent transcriptional regulator
||-------|-------|--|---------||||||||-|--------------------------  1 [R] COG1323 Predicted nucleotidyltransferase
-----------------||-||||--||||||||||||----|||||-||||||||---|||||--  1 [K] COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains
|||---||-|-------|--|---------||||||------|||||-||||---|----------  1 [F] COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase
----------------||----||||----|----|||----||||||||-----|||||||||--  1 [NU] COG1338 Flagellar biosynthesis pathway, component FliP
----------------||------||----|----|||----|||||-||-----||||-------  1 [N] COG1345 Flagellar capping protein
--||--|||--------|-|----||----|----|||----|||||-||-----|--|||-||--  1 [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins
-||||||||-------||||||--|-||||||||||||||||-------|--||||---|||||--  1 [S] COG1354 Uncharacterized conserved protein
--||--------------||-|--|-|||-||---|||----|||||--|-|-------||-||||  1 [S] COG1357 Uncharacterized low-complexity proteins
||||||||||||||||-|--|---------||||||||----------------------------  1 [J] COG1358 Ribosomal protein HS6-type (S12/L30/L7a)
----------------||------||----|----|||----|||||-||-----|||||||||--  1 [N] COG1360 Flagellar motor protein
|||-----||---||-||||-|----||||||--||||-----------|---|||---|||||--  1 [E] COG1364 N-acetylglutamate synthase (N-acetylornithine aminotransferase)
-||-|-||--||-----|--|------||----|-|--------------|-----|||---|--|  1 [R] COG1373 Predicted ATPase (AAA+ superfamily)
----------------||----||||----|----|||----||||||||-----|||||||||--  1 [NU] COG1377 Flagellar biosynthesis pathway, component FlhB
------------------|||||||-||||||||||||||--|||||-||||||||---|||||||  1 [L] COG1381 Recombinational DNA repair protein (RecF pathway)
----------------||||||--||||||||||||||||--||||||||||||||||||||||||  1 [S] COG1385 Uncharacterized protein conserved in bacteria
--|-|||||--------|||||--|-||||||||||||||||-------|--||||---|||||--  1 [K] COG1386 Predicted transcriptional regulator containing the HTH domain
|||---|||--|-----|---|||------|---|||-----------||||---|---||-|---  1 [P] COG1392 Phosphate transport regulator (distant homolog of PhoU)
----------------||||-|----||||||||||||----|||||-||||||||----------  1 [R] COG1399 Predicted metal-binding, possibly nucleic acid-binding protein
||-|-----||||----|||-------||------|-|---------------------|||||--  1 [R] COG1402 Uncharacterized protein, putative amidase
---|--------------||-|-----||||||-|||-----|||---|---|--|---|||||--  1 [V] COG1403 Restriction endonuclease
|-|---|||||-|||-|-||--||--||||||--|||-----|||||-||||---|---|||||--  1 [R] COG1409 Predicted phosphohydrolases
----------------||------||----|----|||----------||-----||||-------  1 [N] COG1419 Flagellar GTP-binding protein
-----------------||||-||--||||||||||||||||----------|--|||||||||--  1 [K] COG1420 Transcriptional regulator of heat shock gene
-----------------|-|--||||-----|||||||----|||||-|||||--|--------||  1 [S] COG1426 Uncharacterized protein conserved in bacteria
---------------------|---|-----||-|||-||||-------------|----------  1 [F] COG1428 Deoxynucleoside kinases
---||-----|----|-|---|---|----|||||||||||||||||-|-||-------||-|---  1 [F] COG1435 Thymidine kinase
-----------------|---|-|--||||||||||||----|||||-|-||--------------  1 [K] COG1438 Arginine repressor
----||||---|-|---------------------|||----|||-|--|-|-||-----------  1 [F] COG1457 Purine-cytosine permease and related proteins
----------------||||||||------||||||||----|||||-||||||||------||--  1 [NU] COG1459 Type II secretory pathway, component PulF
----------------||||-|||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG1466 DNA polymerase III, delta subunit
-----------|--|--|||-|---|||||||---|||----|||||-||||||||---|||||||  1 [G] COG1472 Beta-glucosidase-related glycosidases
||||---||----------|-|--------||||||||-----------|-------------|--  1 [K] COG1476 Predicted transcriptional regulators
--|-------------||--|||||-----||||-|------|||||-||||||||----||||--  1 [H] COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis
-----------------||||--||-----|----|||----------------------------  1 [R] COG1480 Predicted membrane-associated HD superfamily hydrolase
-----------------|--|-----||||||||||||||||------------------------  1 [S] COG1481 Uncharacterized protein conserved in bacteria
--------|----||--|---|---|||||||||||||-|--|||||-|--|--------------  1 [G] COG1482 Phosphomannose isomerase
--|||||||||||||-||||||--|||||-||||||||||||||||||||-|||||--|||||---  1 [H] COG1488 Nicotinic acid phosphoribosyltransferase
-------------||-||--||----|||-||||||||----|||||-||||-|||----------  1 [J] COG1490 D-Tyr-tRNAtyr deacylase
||||||--||-|------||||-----||-|----|-|--------|-||-----|---|||||--  1 [H] COG1492 Cobyric acid synthase
---------|----------|---|-----||||||||||||----------||||---|||||--  1 [T] COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism
----------------|-----||||----|----|||----|||||-||--||||||||||||--  1 [K] COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
----------------||------||----|----|||----|||||-||-----||||-------  1 [NUO] COG1516 Flagellin-specific chaperone FliS
|||-|||-|||||---||-||------||---|--|-|----|||||----|--|---|-------  1 [L] COG1518 Uncharacterized protein predicted to be involved in DNA repair
----------------||||||--||-||||----|||-|---------|--|||||||----|--  1 [K] COG1521 Putative transcriptional regulator, homolog of Bvg accessory factor
----|||||--|-|||-|-|------|---|----|-|-----------|--|-----|-|-||--  1 [R] COG1524 Uncharacterized proteins of the AP superfamily
|||-||--|-||--------------|||-----||||----|||||-||||---|--||||||--  1 [C] COG1526 Uncharacterized protein required for formate dehydrogenase activity
---|--||-||||---|||||-||--|||||----|-|----||||||||||||||---|||||||  1 [J] COG1530 Ribonucleases G and E
||||--||||-||-------|---------||||||||----|||||-||||||||----------  1 [J] COG1534 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein
----------------||----||||----|----|||----||||||||-----|||||||||--  1 [N] COG1536 Flagellar motor switch protein
-------------||---||||||--||||||||||||----|||||-||||||||||||||||--  1 [H] COG1539 Dihydroneopterin aldolase
----------------||||||-|-|||||||||||||----|||||-|||||--|---|||||||  1 [J] COG1544 Ribosome-associated protein Y (PSrp-1)
---|------------||||||----|||||-||-||||||||||||-||--||||||||||||--  1 [R] COG1546 Uncharacterized protein (competence- and mitomycin-induced)
-----------------|---|-----||||----|||----------------------------  1 [S] COG1550 Uncharacterized protein conserved in bacteria
----------------||------||----|----|||----||||||||-----|||||||||--  1 [N] COG1558 Flagellar basal body rod protein
----------------|---||--||||||||||-|||----|||||-||||||||||||||||||  1 [R] COG1559 Predicted periplasmic solute-binding protein
----------------||--|----|----|----|||----|||||-||||||||---|||||--  1 [S] COG1561 Uncharacterized stress-induced protein
-------------||--|--||--|-----|||||||-------------------||-||||---  1 [H] COG1564 Thiamine pyrophosphokinase
-----------------|-|||||--||||||||||||----|||||-||||||||||||||||||  1 [L] COG1570 Exonuclease VII, large subunit
--||||||----|---||--||-----||------|||--------|--|-----|---|||||--  1 [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold
-----------------|--||--------||||||||||--|||||-||||||||||||||||--  1 [S] COG1576 Uncharacterized conserved protein
------------------||-|--||||||||||||||----|||||-||||||||---|||||||  1 [M] COG1589 Cell division septal protein
|-|-----|---------||-|--------|-|-||||----|||||-||-----|---|||||--  1 [C] COG1600 Uncharacterized Fe-S protein
||||||--|||||||-||--||----||||||||||||----||||||||||||||||||||||--  1 [E] COG1605 Chorismate mutase
---|||----|||--------|||--|-------||||----||||||||||-|||||||||||--  1 [I] COG1607 Acyl-CoA hydrolase
-------------|---|--------|||-|----|||----------||--||||--|||||---  1 [S] COG1610 Uncharacterized conserved protein
---|--------|||-|-||-|----||||----||||-----------|--|--|---|||||||  1 [O] COG1612 Uncharacterized protein required for cytochrome oxidase assembly
---|----|-||||--|-||-|----||||----||||----||||||-|--|--|---|||||||  1 [C] COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2
-|||--||||------|-||-|||||----||||||||-|||------------------------  1 [S] COG1624 Uncharacterized conserved protein
|||||||||||||---------------------||||----------------------------  1 [R] COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold
||||||--|||-|||-|---|------||-|---||||----||||||||--|||----|||||--  1 [H] COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)
---|----|-|-----|-||-|||--||||----|||-----|||||-||||||||||||||||||  1 [O] COG1651 Protein-disulfide isomerase
-------------------|-|--||---------||-----|||-|-||-|||||---|||||--  1 [S] COG1652 Uncharacterized protein containing LysM domain
--||---||------------|--------||||||||----|||||-|||||-------------  1 [K] COG1654 Biotin operon repressor
|||-|||||-------|---|----|----|||||||||-||------------------------  1 [L] COG1658 Small primase-like proteins (Toprim domain)
--------------------||----||||||||||||----|||||-||||||||----------  1 [R] COG1660 Predicted P-loop-containing kinase
||||--|||-|||----|---|--------||-|||||--------------|----------|--  1 [CP] COG1668 ABC-type Na+ efflux pump, permease component
------------------------||----|---||||----|||||-||---------|||||--  1 [S] COG1671 Uncharacterized protein conserved in bacteria
----------------||------||----|----|||----||||||||-----|||||||||--  1 [NU] COG1677 Flagellar hook-basal body protein
--|-----|-------|-||------|||||||-||||--------|-||-||||---|-||||||  1 [GM] COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component
|-|-------------||--|---------|----|||--------|-||-----|---||-|---  1 [S] COG1683 Uncharacterized conserved protein
----------------||------||----|----|||----||||||||-----|||||||||--  1 [NU] COG1684 Flagellar biosynthesis pathway, component FliR
----------------|---||---|--------||||||||-----------------|||||--  1 [S] COG1692 Uncharacterized protein conserved in bacteria
-------------||----||---|-----|||||||------------|---||-|-|-|-----  1 [M] COG1696 Predicted membrane protein involved in D-alanine export
---------||-|---||||-|----||||-|||||||----|||||-||-|||||---|||||--  1 [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase
-||--------------|--|---|-------||-|--||---|||---|-|---|---|||||--  1 [S] COG1704 Uncharacterized conserved protein
-----------------||-||--|-----||||||||||||------------------------  1 [H] COG1713 Predicted HD superfamily hydrolase involved in NAD metabolism
|--------|--------||-------||||----|||----------|||--|||||||||||||  1 [S] COG1714 Predicted membrane protein/domain
--|||||||-|-|---||||-|---|-|||-----|||----------||-----|---|||||--  1 [R] COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
-----------------|-|||----||||||||||||----|||||-||||||||||||||||||  1 [L] COG1722 Exonuclease VII small subunit
-----------|---------|-----||------|-|-||-|---|------------|--|---  1 [R] COG1735 Predicted metal-dependent hydrolase with the TIM-barrel fold
--||---------||--|--||---||---||||||||||--|||-|-||||-|||||||||----  1 [S] COG1739 Uncharacterized conserved protein
---|--|||-|-|----|-|-|--||----||||-|||||||-------|-----|---||||---  1 [R] COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein
----------------|-------||----|----|------||||||||-----|||||||||--  1 [N] COG1749 Flagellar hook protein FlgE
||||||||||||||||||||-|--||||||||||||||----|||||-||||||||||||||||||  1 [K] COG1758 DNA-directed RNA polymerase, subunit K/omega
|||||-|||||||---|-----------------||||----|||||-|-||---|--|||||---  1 [H] COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein
----||---------------|----|----|--|||---|||||-|-||--|--|---|||||--  1 [O] COG1764 Predicted redox protein, regulator of disulfide bond formation
----------------||------||----|----|||----||||||||-----|||||||||--  1 [NU] COG1766 Flagellar biosynthesis/type III secretory pathway lipoprotein
-------------|||||--||--|-----||--||||----------------------------  1 [S] COG1774 Uncharacterized homolog of PSP1
--||--|||--------|------|-----|----|||----------|-------|||-------  1 [NT] COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
----------------|--||-||||----||-|||||----|||||-|||||--||||----|||  1 [M] COG1792 Cell shape-determining protein
|-|-||-------||-|----|------------||||----------------------------  1 [L] COG1796 DNA polymerase IV (family X)
||||||--||||------||||-----||-|----|-|--------|--|-----|---||||---  1 [H] COG1797 Cobyrinic acid a,c-diamide synthase
------------------|||-----||||||||||||----------------------------  1 [S] COG1799 Uncharacterized protein conserved in bacteria
--|-|||||-|||---||-|-|------------||||----|||||-||-|---|---||-||--  1 [S] COG1801 Uncharacterized conserved protein
-----------------||------|----|----|||----|||||-|-||---|---|||----  1 [G] COG1803 Methylglyoxal synthase
--------|--------|--||--------|----|||----|||-|-------------------  1 [R] COG1811 Uncharacterized membrane protein, possible Na+ channel or pump
----------------||------||----|----|||----||||||||-----|||||||||--  1 [N] COG1815 Flagellar basal body protein
----------------||||-|||||||||----||||----||||||||||||||||||||||||  1 [J] COG1825 Ribosomal protein L25 (general stress protein Ctc)
--||||--|||||---|-||-|----||||----||||----|||||-||||||||||||||||||  1 [U] COG1826 Sec-independent protein secretion pathway components
|--------|-------|--|---------|-||-|||----------------------------  1 [R] COG1827 Predicted small molecule binding protein (contains 3H domain)
||||||||||||----||||-|----||||-|--||||--------------------|-||||--  1 [F] COG1828 Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component
---|||||--|||---||---|---------|||-|||----|||||--------|--|||-|---  1 [R] COG1832 Predicted CoA-binding protein
--|----------------|||----||||-||||||------||-|--||-||||---|||||-|  1 [I] COG1835 Predicted acyltransferases
----------------||||||||||-|||||||-|||------------------|||-------  1 [R] COG1837 Predicted RNA-binding protein (contains KH domain)
||||||||||||||||||--||--||||||||||||||----||||||||||||||----||||||  1 [J] COG1841 Ribosomal protein L30/L7E
--|-------------|-||-|----|||-|----|||----|||||-||------------||--  1 [KT] COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
----------------||------||----|----|||----||||||||-----|||||||||--  1 [N] COG1843 Flagellar hook capping protein
---|------||||--|-||-|----||||----||||----||||||-|--|--|---|||||||  1 [C] COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3
-----------------|||||--||-|||||||-|||----------------------------  1 [R] COG1847 Predicted RNA-binding protein
---------------------|---|----||||||||----|||||-|-||-||-|||-------  1 [T] COG1854 LuxS protein involved in autoinducer AI2 synthesis
----------------||--|-||-|||||||||||||----||||||||||||||||||||||||  1 [U] COG1862 Preprotein translocase subunit YajC
||||--||---------|---|----|-------||||----------||---------|||--||  1 [P] COG1863 Multisubunit Na+/H+ antiporter, MnhE subunit
----------------||------||----|----|||----||||||||-----||||||||---  1 [N] COG1868 Flagellar motor switch protein
------------------||----||----||||-|||-------|--|-|||-------------  1 [M] COG1876 D-alanyl-D-alanine carboxypeptidase
---|--|||-|-|||-|--|------|||-|||-||||----|||||-||-----|------||--  1 [H] COG1893 Ketopantoate reductase
---|--|||||||||------|------------||------|||||-||-|----||||||||--  1 [R] COG1896 Predicted hydrolases of HD superfamily
|||-||--||||------|||---------|----|----------|--|-----|---|-|----  1 [H] COG1903 Cobalamin biosynthesis protein CbiD
-|||--|||||||---||-|-------------|||-------||-----------||--------  1 [S] COG1912 Uncharacterized conserved protein
----||-----|-||----|||----||||||-|||||----|||||--|||||||---||||---  1 [P] COG1914 Mn2+ and Fe2+ transporters of the NRAMP family
||||||||--||----|||||-----||--|||--|||-------||--|-----||||||||---  1 [S] COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain
|||----|||-------||--|--------||--||------|||||-||--|--|-||----|--  1 [P] COG1918 Fe2+ transport system protein A
-----------------|||-|--|-----|---|||-----|||||-|---|------|-|||--  1 [M] COG1922 Teichoic acid biosynthesis proteins
-|--------------||------------|---||||----|||||-||||||||----||||--  1 [R] COG1923 Uncharacterized host factor I protein
|||-----||------||--|---------||---|------|||---------------------  1 [I] COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain)
--------------------|||||||---||||||||||||||||||||||||||---|||||--  1 [G] COG1925 Phosphotransferase system, HPr-related proteins
------------------|-------|||-||||||||----|||||-||||-||-----------  1 [G] COG1929 Glycerate kinase
||||----|----------|---------------|----------|-------------------  1 [P] COG1930 ABC-type cobalt transport system, periplasmic component
--|----------||----|------||||-|---|||----||||||||||||||--||||||--  1 [HE] COG1932 Phosphoserine aminotransferase
-----------------||||---------||||||||----------------------------  1 [S] COG1939 Uncharacterized protein conserved in bacteria
|-------|----------|------|----|||||||----||||------|||||||||-||--  1 [R] COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog
----------------|||||||-|-|||||---|||||---||||||||||||||||||||||--  1 [I] COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase
------------------||-|----||||-----|||-----------------|----------  1 [S] COG1950 Predicted membrane protein
-----------------|--|---------|---||||----|||---------------------  1 [K] COG1954 Glycerol-3-phosphate responsive antiterminator (mRNA-binding)
---|||-------|---|------------||||||||----|||||-||-||||-------||--  1 [T] COG1956 GAF domain-containing protein
-----------------|||-|--||-----|---|||----------------------------  1 [S] COG1963 Uncharacterized protein conserved in bacteria
--|---------------|-||----||||-||||||-----|||||-|||||--|---|||||--  1 [M] COG1970 Large-conductance mechanosensitive channel
-----------------|||-|----||||||--||||----|||||-|||||--|---|||||--  1 [KT] COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases)
--||||-||-||----|-||-|-----||-----||||----|||||-||||---|||||||||--  1 [H] COG1977 Molybdopterin converting factor, small subunit
-----------------|-||---------|----|||----|||||-|--|--------------  1 [C] COG1979 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family
------------------|||------||||--|||||----|||||-||||---|----|-----  1 [E] COG1982 Arginine/lysine/ornithine decarboxylases
----------------||------||----|----|||----||||||||-----|||||||||--  1 [NU] COG1987 Flagellar biosynthesis pathway, component FliQ
|||---||||--|-----------------|---||||----|||||--|-|--------------  1 [R] COG1988 Predicted membrane-bound metal-dependent hydrolases
||||--||||------||||-|----|||-||||||||----|||||-||||||||--|---||--  1 [NOU] COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
||||||-||||||---||||-|-----||-|----|||----------|----|||||--|-||--  1 [R] COG1994 Zn-dependent proteases
---------------------|--|-|||||---|||||||||||||--|||||||----|--|||  1 [S] COG2001 Uncharacterized protein conserved in bacteria
---|--|||-|||-----||-------||-|----|||----|||--------------||-|---  1 [K] COG2002 Regulators of stationary/sporulation gene expression
--|-------------|||||---------||||||||----|||||-||||||||---||||--|  1 [L] COG2003 DNA repair proteins
---|---------||--|-|||--------|---||-|----|||||-||-----|---|||||--  1 [E] COG2008 Threonine aldolase
|-||---------||------|----||||----||-------------|||||||------||--  1 [E] COG2021 Homoserine acetyltransferase
------------------||||----|||-||||||||-----------|||---|----------  1 [F] COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase
--------------|-----|------|||||||-|------|||----|--------||||||||  1 [R] COG2071 Predicted glutamine amidotransferases
||-|||--||||------|||---------|----|----------|--|-----|---||||---  1 [H] COG2073 Cobalamin biosynthesis protein CbiG
----------------|---------|||-||-|||||-|--|||||-||||---||||-------  1 [O] COG2077 Peroxiredoxin
------------------||----------||||||||----|||||-||||---|---|||-|--  1 [R] COG2081 Predicted flavoproteins
||||||--||||------|||------||-|----|----------|--|-----|---||||---  1 [H] COG2082 Precorrin isomerase
|-|-||----|||---|-||-|-----||-||---|||----|||||-||||-|||-|-|||||--  1 [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
------------------||||----|||-|----|-|----|||-|-||-----|---||||---  1 [H] COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase
------------|--|-----|-|-|-||||---|||------------|---------||-|-||  1 [L] COG2094 3-methyladenine DNA glycosylase
||----------------|||------||-|----|----------|--|-----|---||||---  1 [H] COG2099 Precorrin-6x reductase
--|-||||||||||--||--||-----||---|-||------|||-|--|-----|------|---  1 [R] COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1
--|-||||||---||--|--||--|-----||||||||-|--------|-----------------  1 [F] COG2131 Deoxycytidylate deaminase
-----------------|--||--|-||||||||||||----|||||-||||-|||---|------  1 [R] COG2137 Uncharacterized protein conserved in bacteria
--|---|||----||-----------|---||-|||||----|||-|---||----||-|------  1 [H] COG2145 Hydroxyethylthiazole kinase, sugar kinase family
|||-||||-||||----|---|----||||-|||||||----|---------|--|---|||||--  1 [R] COG2151 Predicted metal-sulfur cluster biosynthetic enzyme
--|---||----|---||-----------------|---------|--------------------  1 [G] COG2152 Predicted glycosylase
---|--||-|-||-----|-------|||-|---||-----------------------||-||--  1 [R] COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold
---------|-------|--------||||||-|||||----||||||||||||||||||||||||  1 [E] COG2171 Tetrahydrodipicolinate N-succinyltransferase
-----------------|--|---------||||||||||||------------------------  1 [L] COG2176 DNA polymerase III, alpha subunit (gram-positive type)
-------------------|||----||||||||-|||----|||||-|||||||----|||||--  1 [D] COG2177 Cell division protein
-----------------|||-|---------|||||||----------------------------  1 [R] COG2179 Predicted hydrolase of the HAD superfamily
----|-||--|||----|---|---------|||||||----|||||-|----------|------  1 [G] COG2182 Maltose-binding periplasmic proteins/domains
-------------|||---||---|-|---|||||||||---|||||-||||||||---||||---  1 [K] COG2183 Transcriptional accessory protein
---------------------|----|||||----|||----|||||-||||-|||---|||||--  1 [K] COG2186 Transcriptional regulators
-----|--|-----------|-----|------|-|--||------|---|||-|-||-|--|---  1 [L] COG2189 Adenine specific DNA methylase Mod
-----------------||||-|||--||-|---||||----------||----------|-|---  1 [TK] COG2208 Serine phosphatase RsbU, regulator of sigma subunit
|-||--||---------|---|----|-------||||----------||---------|||--|-  1 [P] COG2212 Multisubunit Na+/H+ antiporter, MnhF subunit
------------------------------|--|||||-||-|||||||--|--------------  1 [G] COG2213 Phosphotransferase system, mannitol-specific IIBC component
||||||||||||||---|||||----|||-|-||||||----|||||-||-||--|--|||||--|  1 [R] COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold
|-----||-|-------|--||--------|-||-||-----|||||--|--|------|||||--  1 [M] COG2222 Predicted phosphosugar isomerases
--|-||----||-||-||||||||--||||----||||----|||||-||-|||||||||||||||  1 [H] COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis
|||-||-----|----||----------------||--------------------|||-------  1 [L] COG2231 Uncharacterized protein related to Endonuclease III
---|||-----|-------------|-||--|||||----|-----|-||----------|-|---  1 [E] COG2235 Arginine deiminase
||||||--||||------|||-----|||-|----|----------|--|-----|---||||---  1 [H] COG2241 Precorrin-6B methylase 1
||||||--||||------|||-----|||-|----|----------|--|---------||||---  1 [H] COG2242 Precorrin-6B methylase 2
||||||--||||------|||------||-|----|----------|--|-----|---||||---  1 [H] COG2243 Precorrin-2 methylase
---||||||||||-----||------||||||-||||-----|---|--|-----|------||--  1 [S] COG2246 Predicted membrane protein
-----------------||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG2255 Holliday junction resolvasome, helicase subunit
-------------||--|--||----|||||||||||||---|||||-||||||||||||||||--  1 [L] COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
---------------------|----|||-|---||||----|||-|--||----|--||-|----  1 [S] COG2258 Uncharacterized protein conserved in bacteria
----------------||||||--------||||||||----|||||-||||||||||||||||--  1 [J] COG2264 Ribosomal protein L11 methylase
-------||----||--|-|||----||||||--||||----|||||-||||---|---|||||--  1 [I] COG2267 Lysophospholipase
-------------||-|---------|||||----|||---------------------|||||--  1 [R] COG2270 Permeases of the major facilitator superfamily
------------------||||---------|||||||----------------------------  1 [S] COG2302 Uncharacterized conserved protein, contains S4-like domain
--------------|--|---|------------||------|||--------------||-|---  1 [Q] COG2313 Uncharacterized enzyme involved in pigment biosynthesis
---|--||--|||-------||-------------|||-------|--|-------------|--|  1 [E] COG2317 Zn-dependent carboxypeptidase
---|------------|----|------------||||----------------------------  1 [S] COG2322 Predicted membrane protein
-------------------|-|-----||-|---||||----|||-------|||----|||---|  1 [T] COG2337 Growth inhibitor
---|--||-----------|-|----|-----||||||----------------------------  1 [S] COG2339 Predicted membrane protein
--------|----|-|---|||---||---|---||||-----------|---------|||||--  1 [S] COG2340 Uncharacterized protein with SCP/PR1 domains
-----------------|---|--------||||||||----------------------------  1 [R] COG2344 AT-rich DNA-binding protein
----||---------------|----|||-----||------|||||-||--|||||||||-||--  1 [S] COG2353 Uncharacterized conserved protein
------||--|||-|------|||-----------|-|-----------|-----|---|||||--  1 [E] COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog
------||----|--------|-------------||------------------|------|---  1 [E] COG2362 D-aminopeptidase
--------------|----|-|------------||||----|||||-||||-------|||||--  1 [S] COG2363 Uncharacterized small membrane protein
------------------||||-----||||||||||----------------------||-----  1 [V] COG2367 Beta-lactamase class A
-|-------------------|-------------|--------|-----|-|||-----------  1 [S] COG2369 Uncharacterized protein, homolog of phage Mu protein gp30
---------------------|----|--------|||----|||||--------|----|-|---  1 [R] COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC
---------------------|----|---|---||||----|||-|--|----------------  1 [P] COG2382 Enterochelin esterase and related enzymes
---------------------|--------|||||||||-||------|-----------------  1 [R] COG2384 Predicted SAM-dependent methyltransferase
--------|---|-------||----|----|--||------|||---||-|-------|||||--  1 [R] COG2388 Predicted acetyltransferase
------||---||-|--|-|---------------|-|----------------------|--|--  1 [C] COG2421 Predicted acetamidase/formamidase
----||--|-|||---------------------|||-----------------------------  1 [S] COG2427 Uncharacterized conserved protein
-------------------|||----|---||||||||||--|||||-|----|||----------  1 [S] COG2501 Uncharacterized conserved protein
----||----|||------|------|||------|||----|||-|-||--||||----|-||--  1 [G] COG2513 PEP phosphonomutase and related enzymes
----------|-|--------|----|-----||||||---------------------||||---  1 [R] COG2514 Predicted ring-cleavage extradiol dioxygenase
----------|-|------||-----||-|-||||||-----|||||-||||-|||---|||||--  1 [S] COG2606 Uncharacterized conserved protein
--||||--|--||||-||||||----|---|||-|||||-------|--|||-|||||-|||----  1 [P] COG2608 Copper chaperone
--------------|---------------||-||||-----||||||-|-----|----------  1 [G] COG2706 3-carboxymuconate cyclase
------------------------------|----|||----|||||---||-||-----------  1 [S] COG2707 Predicted membrane protein
-----------------|---|--------|---||||----------------------------  1 [R] COG2738 Predicted Zn-dependent protease
--------------------|---------|||||||||||-------------------------  1 [S] COG2739 Uncharacterized protein conserved in bacteria
-------------------|||----||||||||||||||----------------||||||||--  1 [K] COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination
-------------------|-|--------|----||---------------------|-|-|---  1 [V] COG2746 Aminoglycoside N3'-acetyltransferase
----||-------||--|--|---------||||||--|---------|----||-----|-|---  1 [F] COG2759 Formyltetrahydrofolate synthetase
---|-------|---------|----|---|---||||----------|---|--|---|||||--  1 [Q] COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis
---------||-------||-|----||||||--||||----|||||-||-----|---|||||--  1 [K] COG2771 DNA-binding HTH domain-containing proteins
----------------||||||||------||||||||----|||||-||||||||--|---||--  1 [NU] COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB
---------------------|----|---|--|-||-----|||-|--|-----|--|--|----  1 [P] COG2807 Cyanate permease
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG2812 DNA polymerase III, gamma/tau subunits
-|----||-|-|-----|---|---------|||||||----||||||||||-------|||||--  1 [J] COG2813 16S RNA G1207 methylase RsmC
--------------------------|||--|--||||----|||||--||||--||||||-|---  1 [G] COG2814 Arabinose efflux permease
-----------------|--||--||||||||||||||----------------------------  1 [S] COG2815 Uncharacterized protein conserved in bacteria
--------------------------||||-|||||-|----|||||-||||-|||---|||||--  1 [L] COG2818 3-methyladenine DNA glycosylase
----------------------------------|||-----||||-------||-----------  1 [P] COG2822 Predicted periplasmic lipoprotein involved in iron transport
--------------------------|----|||-|------|||||-||||-|||||||||||--  1 [P] COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism
---|----------------|----------|||||||----|||||-||---||-----||||--  1 [L] COG2827 Predicted endonuclease containing a URI domain
-------------------|-|----|||-----|||-----|||||-||-|-|||------|---  1 [P] COG2837 Predicted iron-dependent peroxidase
-------------------|-|------------||--------|-----|--||-----------  1 [R] COG2842 Uncharacterized ATPase, putative transposase
--|------------------|-----||---||-||----------------||-----|-||--  1 [M] COG2843 Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
-||------||||-------------|---||-|-|-----------------||-----------  1 [S] COG2848 Uncharacterized conserved protein
-------------------|-|-------------|------|-------|--||-----|--|--  1 [S] COG2852 Uncharacterized protein conserved in bacteria
--------|-----------|-----|----|||||------|||||--|||-|||--||||||--  1 [S] COG2855 Predicted membrane protein
--------------------|---||----|||||||||-||------------------------  1 [J] COG2868 Predicted ribosomal protein
--||---------||--|---|----|||-||---|-|-----------|-|---|--|||||---  1 [E] COG2873 O-acetylhomoserine sulfhydrylase
||||||--||||------|||------||-|----|----------|--|-----|---||||---  1 [H] COG2875 Precorrin-4 methylase
----||-|--|||----|||||||------|-|-||||---------------|------------  1 [E] COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase
-------------------|-|----||||||||-|||----|||||-|||||||----|||||--  1 [D] COG2884 Predicted ATPase involved in cell division
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG2890 Methylase of polypeptide chain release factors
-------------------|----|------|-|||||----|||||-|||||--|----------  1 [M] COG2891 Cell shape-determining protein
----------------||||||--------|----|||----||||||||--||||||-||||---  1 [D] COG2894 Septum formation inhibitor-activating ATPase
|||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||--  1 [H] COG2896 Molybdenum cofactor biosynthesis enzyme
--|-----------------------||||-|--|||------------|--|--|---|||||--  1 [S] COG2898 Uncharacterized conserved protein
-------------------------------|-|-||-----------||-----|--|||-|---  1 [R] COG2910 Putative NADH-flavin reductase
------------------------------|----|------||||||||-|--------------  1 [H] COG2918 Gamma-glutamylcysteine synthetase
------------------------||||||-|||||||----||||||||||||||---|||||||  1 [D] COG2919 Septum formation initiator
------------------|--------||--|--||----------------|-------|-||--  1 [R] COG2936 Predicted acyl esterases
--------------------------|-------||||----|||||-||||---|---|||||--  1 [R] COG2962 Predicted permeases
|------------||-----|-----|||-|--|||-|----|||||-|-|||-----|-------  1 [S] COG2966 Uncharacterized conserved protein
--------------------|---------||||||||----------||----------------  1 [S] COG2996 Uncharacterized protein conserved in bacteria
--------------------|----||----|||||---|--|||||-|-||---------|----  1 [G] COG3010 Putative N-acetylmannosamine-6-phosphate epimerase
-----------------------|------|---||||----|||||-|||||||----|||||||  1 [S] COG3027 Uncharacterized protein conserved in bacteria
--||----------------------||-------|||----|||||-||-|-||----||||---  1 [R] COG3030 Protein affecting phage T7 exclusion by the F plasmid
--------------------------|-----||||-|-||-|||||-|--|--------------  1 [S] COG3037 Uncharacterized protein conserved in bacteria
------------------------------|--|||------|||||-||||-|-|----|-||-|  1 [K] COG3070 Regulator of competence-specific genes
-------------------------------|||||||----|||||-||||--------------  1 [S] COG3091 Uncharacterized protein conserved in bacteria
-------------|||----------|---||--|||-----|||||-|---|||--------|--  1 [E] COG3104 Dipeptide/tripeptide permease
----------------------------------||||----||||||-|--|--|---|-|||--  1 [C] COG3125 Heme/copper-type cytochrome/quinol oxidase, subunit 4
--|----------------|------|----|--||------|||||-||---------|||||--  1 [R] COG3153 Predicted acetyltransferase
--||-----------------|-----||--|---|||-----------|-----|---||-||-|  1 [R] COG3173 Predicted aminoglycoside phosphotransferase
--||------------|--||-----|-----|-||-------|||---|-|-|||||-||-|--|  1 [S] COG3177 Uncharacterized conserved protein
--------------------|--------------||-----|||-|--|----------------  1 [E] COG3192 Ethanolamine utilization protein
----------||------|----------------|------|---|--|-----|---|-|||--  1 [R] COG3193 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol
--|---------------------------|----||-----|||||--|-----|------|---  1 [M] COG3209 Rhs family protein
--|-----------------|-----------|-||||----------||---||-------||--  1 [S] COG3212 Predicted membrane protein
-------------------------------|---||-----|||||--||---------------  1 [S] COG3223 Predicted membrane protein
-------------------|------|----||||||-----|||-|--|---------||-||--  1 [S] COG3237 Uncharacterized protein conserved in bacteria
---|||-----||--------|----||||----||||----------------------------  1 [S] COG3253 Uncharacterized conserved protein
----||-----------------------------|||----|||||-----------|||||---  1 [S] COG3254 Uncharacterized conserved protein
--------------------|-----||-||---||||-----------|----------------  1 [S] COG3323 Uncharacterized protein conserved in bacteria
---|---------|---------------------|-|--------|-|-----------------  1 [G] COG3325 Chitinase
--|----------------------------|||-|||--------|--|---||-|--|------  1 [S] COG3326 Predicted membrane protein
-------------------------------|||||||||||------------------------  1 [R] COG3331 Penicillin-binding protein-related factor A, putative recombinase
-------------------|---------------|-|----------|--|----||--|-|---  1 [P] COG3338 Carbonic anhydrase
-------------------|||----|--------|||----|||-|---||--------------  1 [E] COG3340 Peptidase E
-------------------------------||||||||-||------------------------  1 [K] COG3343 DNA-directed RNA polymerase, delta subunit
---|-------|-------|------|||--||--|-------|||------|--|----------  1 [R] COG3378 Predicted ATPase
|---||-----|----------------------|||----------------------||-|---  1 [R] COG3383 Uncharacterized anaerobic dehydrogenase
--|----------------|----|--||------|-|-------------------------|--  1 [R] COG3393 Predicted acetyltransferase
-------------------------------|---|-|-------|--||----------------  1 [S] COG3397 Uncharacterized protein conserved in bacteria
---|----------------------||------||||----------------------------  1 [S] COG3402 Uncharacterized conserved protein
---|||-----|-|||---------|-----|||||------------------------------  1 [I] COG3407 Mevalonate pyrophosphate decarboxylase
||||||||||||||||---------|-----||||||--------|-----------------|--  1 [I] COG3425 3-hydroxy-3-methylglutaryl CoA synthase
-----------------|---|--------|----||-----------------------------  1 [C] COG3426 Butyrate kinase
---|----------------------|||-----||||----------------------------  1 [S] COG3428 Predicted membrane protein
------------------------------|----|||----|||-|--------|------||--  1 [L] COG3449 DNA gyrase inhibitor
-----------------|------------|----|---------|--|----------||||---  1 [G] COG3459 Cellobiose phosphorylase
-------------------------------|---|------------||----------------  1 [G] COG3469 Chitinase
--------------------------||||-|||-|||----------------------------  1 [T] COG3480 Predicted secreted protein containing a PDZ domain
-|-------|----------|---------||||||||----------------------|-----  1 [R] COG3481 Predicted HD-superfamily hydrolase
--------------------------------|--|---------------|--|---|-------  1 [S] COG3513 Uncharacterized protein conserved in bacteria
--|---------------------------||-||||-----------|-----------------  1 [Q] COG3527 Alpha-acetolactate decarboxylase
------|----|-----------------------|-|---------------------|--|---  1 [S] COG3535 Uncharacterized conserved protein
-------------------------------|||||||||--------------------------  1 [J] COG3557 Uncharacterized domain/protein associated with RNAses G and E
-------------|----------------||--||-------------|---||----|-|----  1 [R] COG3560 Predicted oxidoreductase related to nitroreductase
-----------------------------------|--------------|-|---------|---  1 [S] COG3566 Uncharacterized protein conserved in bacteria
-----------------------------------|--------------|-|---------|---  1 [S] COG3567 Uncharacterized protein conserved in bacteria
--------------------------------||-|------|||-|--|--|--|---|||||--  1 [R] COG3568 Metal-dependent hydrolase
-------------|----------|------|||-|------------------------------  1 [E] COG3579 Aminopeptidase C
----------------||--|---------||---|------------------------------  1 [S] COG3580 Uncharacterized protein conserved in bacteria
----------------||--|---------||---|------------------------------  1 [S] COG3581 Uncharacterized protein conserved in bacteria
--------------------------|||||----|||----------------------------  1 [S] COG3583 Uncharacterized protein conserved in bacteria
-----------|-------------|-----||-||-|----------------------------  1 [S] COG3589 Uncharacterized conserved protein
--|----------------------------|---|------|||-----------------|---  1 [S] COG3592 Uncharacterized conserved protein
--|---------------------------|---|||------------|--|---------|---  1 [G] COG3594 Fucose 4-O-acetylase and related acetyltransferases
------||---------|------------|||||||-----------------------------  1 [S] COG3601 Predicted membrane protein
--------------------------|----|--||-|---------------------||-|---  1 [R] COG3607 Predicted lactoylglutathione lyase
|------------||-----|-----|||-|--|||-|----|||||-|-|||-----|-------  1 [S] COG3610 Uncharacterized conserved protein
-------------------------------||||||||-||------------------------  1 [L] COG3611 Replication initiation/membrane attachment protein
--|---------------|-|------||-||||-||------------|-----|---||||---  1 [S] COG3619 Predicted membrane protein
--------------------|---|-------|-||-|----------------------------  1 [R] COG3641 Predicted membrane protein, putative toxin regulator
-------------------|------|---|-||-|||-----------|-------------|--  1 [K] COG3655 Predicted transcriptional regulator
----------------------------------||-|-----------|----------|--|--  1 [G] COG3664 Beta-xylosidase
--------------------------------||||------|||-|---------------|---  1 [G] COG3684 Tagatose-1,6-bisphosphate aldolase
------------------||----------|-|-||||----------------------------  1 [R] COG3688 Predicted RNA-binding protein containing a PIN domain
------------------||----------|-||-|||----------------------------  1 [S] COG3689 Predicted membrane protein
--------------|------|----|||--|---|------|||||-||----------------  1 [L] COG3695 Predicted methylated DNA-protein cysteine methyltransferase
----------------|-||-|--------||---|||-----------|---|||---|||||--  1 [E] COG3705 ATP phosphoribosyltransferase involved in histidine biosynthesis
--------------------|------||||----|-------------|-----|---||-||--  1 [T] COG3707 Response regulator with putative antiterminator output domain
--------------------------|--------|||-------||--------|---|||||--  1 [G] COG3718 Uncharacterized enzyme involved in inositol metabolism
-------------------------------||-|||------|||---|------------|---  1 [L] COG3728 Phage terminase, small subunit
-----------------------------------|-|----|||-|----|----------|---  1 [G] COG3730 Phosphotransferase system sorbitol-specific component IIC
-----------------------------------|-|----|||-|----|----------|---  1 [G] COG3731 Phosphotransferase system sorbitol-specific component IIA
-----------------------------------|-|----||--|----|----------|---  1 [G] COG3732 Phosphotransferase system sorbitol-specific component IIBC
-------------------------------|---|||-------------|-------|---|--  1 [S] COG3739 Uncharacterized integral membrane protein
---------------------------||--|---|-------||-|--------|---|---|--  1 [R] COG3740 Phage head maturation protease
--------------|------------||--|---|-----------------------|--||--  1 [S] COG3752 Predicted membrane protein
--------------------------|----|-|||--------------|--|||---|--|---  1 [S] COG3759 Predicted membrane protein
-------------------------------|||||||||||------------------------  1 [S] COG3763 Uncharacterized protein conserved in bacteria
|--------|----------------|---||||||||----------------------------  1 [M] COG3764 Sortase (surface protein transpeptidase)
---------------------------||||----|-----------------------|||||--  1 [S] COG3786 Uncharacterized protein conserved in bacteria
---------------------------||----|-|-----------------------||-||--  1 [S] COG3797 Uncharacterized protein conserved in bacteria
----------------|-------------|----|||----|||-|--|-----|----------  1 [KT] COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
-||-----|||---------------||||||-|-|-------------|---||-----------  1 [T] COG3830 ACT domain-containing protein
--|--------------|--------|||-|---||||-----------|-----|---||-||--  1 [S] COG3832 Uncharacterized conserved protein
----|--|--||-----|---|---------|||||||-|--|||||-|-----------------  1 [G] COG3833 ABC-type maltose transport systems, permease component
|||||||||||||---||||||--|-||||||||||||-||||||||-||-||--|--|||||---  1 [G] COG3839 ABC-type sugar transport systems, ATPase components
---|--|||-|-|----|-|-|--||----||||-||-||||-------|-----|---||||---  1 [R] COG3845 ABC-type uncharacterized transport systems, ATPase components
---|--------------||--------------||||----------------------------  1 [T] COG3848 Phosphohistidine swiveling domain
--|------------------|--------|||-||||----------------------------  1 [P] COG3853 Uncharacterized protein involved in tellurite resistance
--------------------|---------||--|||-----------------------------  1 [G] COG3855 Uncharacterized protein conserved in bacteria
------------------------------||||||||----------------------------  1 [L] COG3857 ATP-dependent nuclease, subunit B
------------------------------|||--|||----------------------------  1 [S] COG3859 Predicted membrane protein
--------------------------|---||--||-------------|-----|---||-|---  1 [S] COG3865 Uncharacterized protein conserved in bacteria
----------------------||------|---||||----------------------------  1 [E] COG3869 Arginine kinase
---------------------|--------|---||||----------------------------  1 [S] COG3870 Uncharacterized protein conserved in bacteria
-------------------|-|--------|---|||----------------------|------  1 [R] COG3871 Uncharacterized stress protein (general stress protein 26)
-----------------|--|---------|----|||----------------------------  1 [R] COG3872 Predicted metal-dependent enzyme
----------------------||------|---||||----------------------------  1 [S] COG3880 Uncharacterized protein with conserved CXXC pairs
------------------------------||||||||-|--------------------------  1 [T] COG3887 Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain
-----------------|------------||||||||----------------------------  1 [S] COG3906 Uncharacterized protein conserved in bacteria
|-|---------------|||------||||----|-----------------------|||||--  1 [T] COG3920 Signal transduction histidine kinase
--------------------------|--------|||-------||--------|---|||||--  1 [E] COG3962 Acetolactate synthase
-------------------------------||||||-----------------------------  1 [M] COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
-------------------------------||--|------|||-|--|-----|----------  1 [R] COG3969 Predicted phosphoadenosine phosphosulfate sulfotransferase
-------------------|---------------|-|---------------------|-||---  1 [E] COG4091 Predicted homoserine dehydrogenase
-------------------------------|||||||----------------------------  1 [L] COG4098 Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein)
------------------||----------|---||||----------------------------  1 [P] COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
------------------||-|----|---||||||------||||||||||||||---|||||--  1 [J] COG4108 Peptide chain release factor RF-3
------------------------------||||||||----------------------------  1 [K] COG4109 Predicted transcriptional regulator containing CBS domains
-------------------------------|||||||----------------------------  1 [S] COG4116 Uncharacterized protein conserved in bacteria
--||--------|-|-|-||||----||||||||||||-----------|---||-------|---  1 [R] COG4122 Predicted O-methyltransferase
----------------||--|---------||||||||||--|||||-|-||----||||||||--  1 [R] COG4123 Predicted O-methyltransferase
--|---------|---|-||------|||-----||||----|||||-||||---|||||||||--  1 [P] COG4149 ABC-type molybdate transport system, permease component
-||----------------------------|-|||||-------------------------|--  1 [R] COG4152 ABC-type uncharacterized transport system, ATPase component
--|----------------------|-----||--||-----|||||--|-----|---||||---  1 [E] COG4175 ABC-type proline/glycine betaine transport system, ATPase component
--|----------------------|-----||--||-----|||||--|-----|---||||---  1 [E] COG4176 ABC-type proline/glycine betaine transport system, permease component
----|------|--------------|---|----|------------------------------  1 [R] COG4194 Predicted membrane protein
----||-----------|------------|----|------------------------------  1 [S] COG4198 Uncharacterized conserved protein
-------------------------------|||||||----------------------------  1 [S] COG4199 Uncharacterized protein conserved in bacteria
-------------------------------|||-|||---------------------|------  1 [G] COG4209 ABC-type polysaccharide transport system, permease component
---|---------||---||||----|||--|-|||------|||-|-||||||||||||||----  1 [R] COG4221 Short-chain alcohol dehydrogenase of unknown specificity
----||-----|-------------------|---|------------------------------  1 [S] COG4272 Predicted membrane protein
-------------|------|----------|-|-|---------------|--------------  1 [S] COG4283 Uncharacterized conserved protein
---------------------|------------||-------------------|---||-----  1 [S] COG4292 Predicted membrane protein
--------------------|---------|----|------|||-|--|-----|----------  1 [E] COG4302 Ethanolamine ammonia-lyase, small subunit
--------------------|---------|----|------|||-|--|-----|----------  1 [E] COG4303 Ethanolamine ammonia-lyase, large subunit
------------------||----|---------||------------------------------  1 [S] COG4330 Predicted membrane protein
---|------------------------------||||----------------------------  1 [S] COG4347 Predicted membrane protein
---------------------|---------|--||------------------------------  1 [S] COG4367 Uncharacterized protein conserved in bacteria
---------------------|---------|-|||-|----------||-----|----------  1 [S] COG4392 Predicted membrane protein
------------------|||-------------||||----------------------------  1 [S] COG4399 Uncharacterized protein conserved in bacteria
------------------||---------------|||----------------------------  1 [E] COG4401 Chorismate mutase
------------------------------||-|-|||-----|-||-------------------  1 [S] COG4405 Uncharacterized protein conserved in bacteria
-------------------|--------------||||----------------------|-||--  1 [S] COG4430 Uncharacterized protein conserved in bacteria
------------------------|-----||||-|------------------------------  1 [S] COG4443 Uncharacterized protein conserved in bacteria
------------------------------||||||||----------------------------  1 [K] COG4463 Transcriptional repressor of class III stress genes
------------------------------||||||||----------------------------  1 [K] COG4465 Pleiotropic transcriptional repressor
------------------------------||||||||----------------------------  1 [S] COG4466 Uncharacterized protein conserved in bacteria
-------------------------------|||||||----------------------------  1 [S] COG4467 Uncharacterized protein conserved in bacteria
-------------------------------|||||||----------------------------  1 [R] COG4469 Competence protein
-------------------------------|||||||----------------------------  1 [S] COG4470 Uncharacterized protein conserved in bacteria
-------------------------------|||||||----------------------------  1 [S] COG4471 Uncharacterized protein conserved in bacteria
------------------------------||||||-|----------------------------  1 [S] COG4472 Uncharacterized protein conserved in bacteria
-------------------------------|||||||----------------------------  1 [U] COG4473 Predicted ABC-type exoprotein transport system, permease component
-------------------------------|||||||----------------------------  1 [S] COG4474 Uncharacterized protein conserved in bacteria
-------------------------------|||||||----------------------------  1 [S] COG4476 Uncharacterized protein conserved in bacteria
-------------------------------|||||||----------------------------  1 [D] COG4477 Negative regulator of septation ring formation
-------------------------------||||||-----------------------------  1 [S] COG4479 Uncharacterized protein conserved in bacteria
------------------------------|-||||-|----------------------------  1 [S] COG4481 Uncharacterized protein conserved in bacteria
-------------------------------||||||-----------------------------  1 [S] COG4483 Uncharacterized protein conserved in bacteria
-------------------------------|--||||----------------------------  1 [S] COG4493 Uncharacterized protein conserved in bacteria
------------------------------|---||||--------------|-------------  1 [S] COG4496 Uncharacterized protein conserved in bacteria
------------------------------|---||||----------------------------  1 [S] COG4499 Predicted membrane protein
------------------------------|---||||----------------------------  1 [S] COG4506 Uncharacterized protein conserved in bacteria
--------------------------------|-||-|----------------------------  1 [S] COG4509 Uncharacterized protein conserved in bacteria
------------------------------|---||-|----------------------------  1 [OTK] COG4512 Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide
---------------------|-------------|||----|||||-|-----------------  1 [R] COG4533 ABC-type uncharacterized transport system, periplasmic component
-------------------------------|||||||----------------------------  1 [U] COG4537 Competence protein ComGC
------------------------------|----|----------|---------------|---  1 [Q] COG4542 Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase
-----------------------------------||----------------------||||---  1 [S] COG4549 Uncharacterized protein conserved in bacteria
-------------------------------||-||||----------------------------  1 [S] COG4550 Predicted membrane protein
--|------------------------||-----||-|-----|||---------|---||-|---  1 [L] COG4584 Transposase and inactivated derivatives
------------------||-|----|||-||||||||-----------|-----|---||-||--  1 [T] COG4585 Signal transduction histidine kinase
---|--|||-|-|----|-|-|--||----||||-||-||||-------|-----|---||||---  1 [R] COG4603 ABC-type uncharacterized transport system, permease component
--|||||||-|||---||--||||-||---||||||||-||||||||-||||---||||||||---  1 [E] COG4608 ABC-type oligopeptide transport system, ATPase component
------------------------------||--||------|||-----------------|---  1 [R] COG4626 Phage terminase-like protein, large subunit
--|--------------|--|---||---------|------||||||||||--------------  1 [C] COG4656 Predicted NADH:ubiquinone oxidoreductase, subunit RnfC
---------------------|--------||-|||||--|-||||||||||---|----------  1 [G] COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain
---||-----|-|-------|-------------||-|----|||-|--------|----|||---  1 [I] COG4670 Acyl CoA:acetate/3-ketoacid CoA transferase
------------------------------||||-|------------------------------  1 [S] COG4687 Uncharacterized protein conserved in bacteria
-------------------------------||--|||----------------------------  1 [S] COG4698 Uncharacterized protein conserved in bacteria
-------------------------------|||||------------------------------  1 [S] COG4699 Uncharacterized protein conserved in bacteria
-------------------------------|||-||-----------------------------  1 [S] COG4703 Uncharacterized protein conserved in bacteria
------------------------------||||-|------------------------------  1 [S] COG4708 Predicted membrane protein
------------------------------|-||||---------------------------|--  1 [S] COG4709 Predicted membrane protein
-------------------------------||-||------------------------------  1 [S] COG4716 Myosin-crossreactive antigen
--|-------------------------------|||-----------------------|-----  1 [S] COG4717 Uncharacterized conserved protein
------------------------------|||--|||----------------------------  1 [S] COG4722 Phage-related protein
--|----------------|-----||--------|------------------------------  1 [S] COG4748 Uncharacterized conserved protein
--------------------|-----------||||||----------------------------  1 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
-------------------------------|||||||----------------------------  1 [S] COG4758 Predicted membrane protein
--------------------|--------------|------|||-|------------|------  1 [E] COG4766 Ethanolamine utilization protein
-------------------------------|||||||----------------------------  1 [R] COG4768 Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain
-----------------|--|---|------|---|------------------------------  1 [S] COG4769 Predicted membrane protein
-------------------------------|||||------------------------------  1 [C] COG4781 Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase
----------------||------||----|----|||----||||||||-----|||||||||--  1 [N] COG4786 Flagellar basal body rod protein
-----------------------------------|||----|||||-------------------  1 [G] COG4806 L-rhamnose isomerase
----------------------------------||------|||-|-------------------  1 [S] COG4808 Uncharacterized protein conserved in bacteria
--------------------|--------------|------|||-|-------------------  1 [E] COG4810 Ethanolamine utilization protein
-----------------------------------|------|||||----|--------------  1 [S] COG4811 Predicted membrane protein
--------------------|--------------|------|||-|-------------------  1 [E] COG4812 Ethanolamine utilization cobalamin adenosyltransferase
-----------------------------------|-|---------------------||||---  1 [G] COG4813 Trehalose utilization protein
--------------------------|-------||------------------------------  1 [S] COG4815 Uncharacterized protein conserved in bacteria
-------------------------------|---|-|----------------------------  1 [S] COG4817 Uncharacterized protein conserved in bacteria
--------------------|--------------|------|||-|-------------------  1 [E] COG4819 Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition
--------------------|--------------|------|||-|-------------------  1 [E] COG4820 Ethanolamine utilization protein, possible chaperonin
--------------------|---------|----|----------|-------------------  1 [H] COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase
------------------------------|----|||----------------------------  1 [R] COG4824 Phage-related holin (Lysis protein)
--|-----------------|----------|---|------------------------------  1 [S] COG4832 Uncharacterized conserved protein
--------------------------|||------|------------------------------  1 [G] COG4833 Predicted glycosyl hydrolase
-----------------------------------|----------------|---------|---  1 [S] COG4834 Uncharacterized protein conserved in bacteria
-------------------------------|||-|------------------------------  1 [S] COG4835 Uncharacterized protein conserved in bacteria
----------------------------------||||----------------------------  1 [S] COG4836 Predicted membrane protein
----------------------------------||||----------------------------  1 [S] COG4837 Uncharacterized protein conserved in bacteria
----------------------------------||||----------------------------  1 [S] COG4838 Uncharacterized protein conserved in bacteria
-------------------------------|||||||----------------------------  1 [D] COG4839 Protein required for the initiation of cell division
----------------------------------||||----------------------------  1 [S] COG4840 Uncharacterized protein conserved in bacteria
----------------------------------||||----------------------------  1 [S] COG4841 Uncharacterized protein conserved in bacteria
--------------------------|||||---||||----------------------------  1 [S] COG4842 Uncharacterized protein conserved in bacteria
----------------------------------||||----------------------------  1 [S] COG4843 Uncharacterized protein conserved in bacteria
----------------------------------||||----------------------------  1 [S] COG4844 Uncharacterized protein conserved in bacteria
----------------------------------||||----------------------------  1 [O] COG4846 Membrane protein involved in cytochrome C biogenesis
----------------------------------||||----------------------------  1 [S] COG4848 Uncharacterized protein conserved in bacteria
----------------------------------||||----------------------------  1 [R] COG4851 Protein involved in sex pheromone biosynthesis
-------------------------------|---|-----------------------|--|---  1 [S] COG4852 Predicted membrane protein
----------------------------------||||----------------------------  1 [S] COG4853 Uncharacterized protein conserved in bacteria
------------------------------|-||||||----------------------------  1 [S] COG4856 Uncharacterized protein conserved in bacteria
-------------------------------|||-|------------------------------  1 [S] COG4858 Uncharacterized membrane-bound protein conserved in bacteria
-------------------------------|||||||----------------------------  1 [OTN] COG4862 Negative regulator of genetic competence, sporulation and motility
----------------------------------||||----------------------------  1 [S] COG4863 Uncharacterized protein conserved in bacteria
----------------------------------||||----------------------------  1 [S] COG4864 Uncharacterized protein conserved in bacteria
----------------------------------|||-----------------------------  1 [S] COG4873 Uncharacterized protein conserved in bacteria
----------------------------------|||-----------------------------  1 [S] COG4876 Uncharacterized protein conserved in bacteria
--------------------|--------------|------|-----------------------  1 [S] COG4884 Uncharacterized protein conserved in bacteria
--------------------------|||------|--------------------||--------  1 [R] COG4889 Predicted helicase
----------------------------------|||-----------------------------  1 [S] COG4896 Uncharacterized protein conserved in bacteria
----------------------------------|||-----------------------------  1 [S] COG4897 Uncharacterized protein conserved in bacteria
---------------------------------|-|------------------------|-----  1 [S] COG4898 Uncharacterized protein conserved in bacteria
----------------------------------|||-----------------------------  1 [K] COG4903 Genetic competence transcription factor
------------------------------||---|------------------------------  1 [S] COG4905 Predicted membrane protein
--|------------------------||-|----|------------------------------  1 [R] COG4908 Uncharacterized protein containing a NRPS condensation (elongation) domain
-----------------------------------|----------|---------------|---  1 [Q] COG4909 Propanediol dehydratase, large subunit
-----------------------------------|----------|---------------|---  1 [Q] COG4910 Propanediol dehydratase, small subunit
--|-----------------|-----|----|---|------------------------|-|--|  1 [L] COG4912 Predicted DNA alkylation repair enzyme
-------------------------------|--|||-----------------------------  1 [R] COG4915 5-bromo-4-chloroindolyl phosphate hydrolysis protein
--------------------|--------------|------|||-|-------------------  1 [E] COG4917 Ethanolamine utilization protein
-------------------------------|---||-----------------------------  1 [S] COG4918 Uncharacterized protein conserved in bacteria
------------------------------|||--|------------------------------  1 [S] COG4926 Phage-related protein
------------------------------|----|----------|-------------------  1 [TK] COG4936 Predicted sensor domain
----------|------------------------|------------|-----------------  1 [S] COG4938 Uncharacterized conserved protein
--------------------|---|----------|------------------------------  1 [S] COG4939 Major membrane immunogen, membrane-anchored lipoprotein
-------------------------------|||||||------------------|||-------  1 [U] COG4940 Competence protein ComGF
----------------------------------||||----------------------------  1 [S] COG4955 Uncharacterized protein conserved in bacteria
------------------||-|--------||--||||----------------------------  1 [R] COG4956 Integral membrane protein (PIN domain superfamily)
--||-------------------------------|--------------------------|---  1 [S] COG4983 Uncharacterized conserved protein
-------------------------------|--||||----|||||-|-||-------|-|-|--  1 [CO] COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components
------------------------------|--|||||----|||||-|----------|--|---  1 [R] COG4989 Predicted oxidoreductase
|||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||--  1 [E] COG4992 Ornithine/acetylornithine aminotransferase
------------------------------|----|-------------------|----------  1 [S] COG4994 Uncharacterized protein conserved in bacteria
---------------------|---------|||||||----------------------------  1 [T] COG5002 Signal transduction histidine kinase
--|------------------|---------|--|||-----------------------------  1 [S] COG5280 Phage-related minor tail protein
------------------------------||---|-------||-|-----|-------------  1 [S] COG5283 Phage-related tail protein
-------------------------------|--|||-----------------------------  1 [S] COG5294 Uncharacterized protein conserved in bacteria
-----------------------------------||------------------|----------  1 [S] COG5298 Uncharacterized protein conserved in bacteria
-----------------------------------|-----------------------||||---  1 [R] COG5350 Predicted protein tyrosine phosphatase
-------------------------------|-|-|||----------------------------  1 [S] COG5353 Uncharacterized protein conserved in bacteria
--|--------------------------------|--------------------------|--|  1 [R] COG5362 Phage-related terminase
----------------||-------|--------||||----|||||||||||--|||||||||||  1 [O] COG5405 ATP-dependent protease HslVU (ClpYQ), peptidase subunit
-----------------------------------|-|--------------|------------|  1 [S] COG5410 Uncharacterized protein conserved in bacteria
--------------------------------|-||-|----------------------------  1 [S] COG5412 Phage-related protein
--------------------------||||-----|||---------------|||----------  1 [S] COG5416 Uncharacterized integral membrane protein
----------------------------------||||----------------------------  1 [S] COG5417 Uncharacterized small protein
-----------------------------------|-|---------------------|-|-|--  1 [S] COG5437 Predicted secreted protein
----------------------------------||||----------------------------  1 [S] COG5444 Uncharacterized conserved protein
------------------------------|----||------||||-------------------  1 [N] COG5492 Bacterial surface proteins containing Ig-like domains
-------------------------------|||||||----------------------------  1 [S] COG5503 Uncharacterized conserved small protein
--------------------------------||-|||----------------------------  1 [S] COG5506 Uncharacterized conserved protein
-----------------------------------||---------|--------|----------  1 [R] COG5518 Bacteriophage capsid portal protein
--------------------------------||-||-----------------------------  1 [S] COG5521 Predicted integral membrane protein
------------------------------||||-|------------------------------  1 [S] COG5523 Predicted integral membrane protein
------------------------------|---||-----------------|------------  1 [L] COG5527 Protein involved in initiation of plasmid replication
---------------------------||--|--||------|||-|-------------------  1 [R] COG5562 Phage envelope protein
-------------------------------|||-|||----------------------------  1 [S] COG5578 Predicted integral membrane protein
----------------------------------||||----------------------------  1 [S] COG5582 Uncharacterized conserved protein
----------------------------------||||----------------------------  1 [S] COG5584 Predicted small secreted protein
--||-------------|---|--------|----|-|-----------------|----------  1 [S] COG5652 Predicted integral membrane protein
------------------------------|---||-|----------------------------  1 [L] COG5655 Plasmid rolling circle replication initiator protein and truncated derivatives
|||||||||||||||---||||--------|-|-|-||----|||-|-||-|||||||-||||---  0 [E] COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family
||-||||||||--|--|||-------|||-|--||-||----------------------------  0 [S] COG0011 Uncharacterized conserved protein
-|----||---|------||------|||-------|-----|||||-||-|--------------  0 [F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)
-|||||||||-||||-|-||||----|||-||||---|----|||||-|-||-|||---|-|||--  0 [P] COG0038 Chloride channel protein EriC
|||-||||||||||--|-||-|||------------||----|||||-||-|-|||||||||-|||  0 [H] COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases
||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||--||||||||  0 [C] COG0045 Succinyl-CoA synthetase, beta subunit
||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||--  0 [H] COG0054 Riboflavin synthase beta-chain
-||---||--||-|--|-||||||--|||-||||--||----|||||-||||-------||-|---  0 [G] COG0058 Glucan phosphorylase
|||||||||||||||-||||-|-----||||---|-||----||||||||--|--|---|||||||  0 [O] COG0071 Molecular chaperone (small heat shock protein)
||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||--||||||||  0 [C] COG0074 Succinyl-CoA synthetase, alpha subunit
||||||||||||||--||||-|--------||--|-||--------|-||------||-||-||--  0 [E] COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase
||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||--  0 [H] COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase
-------------||-||||||||--||||||-||-||----||||||||||||||||||||||--  0 [H] COG0117 Pyrimidine deaminase
|-||--|||---||||--|--|-----||-|-----||-|--|||||-||--|--|---|||||--  0 [L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase
||||--|||||||||||-||-|------------|-||----------||---|||---|||||--  0 [BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein
-|-----------|--|-|||--|--|||||---|-||----||||||||||||||||||-|||--  0 [H] COG0132 Dethiobiotin synthetase
------|---|--||--|--|---|-|||-||-|--||----|||||-|-||--------------  0 [G] COG0153 Galactokinase
--------|-||-||-|-||-|----|||-|-----||----||||||||--||||---|||||--  0 [P] COG0155 Sulfite reductase, beta subunit (hemoprotein)
-|--||||-----||||-||||||---|||----|-||----|||||-||||||||||||||||||  0 [H] COG0156 7-keto-8-aminopelargonate synthetase and related enzymes
--||||||--|||||----|-|----|||||---|-||----|||||-|||----|---||||---  0 [E] COG0160 4-aminobutyrate aminotransferase and related aminotransferases
-|-----------||-|---||-|--|||||---|-||----||||||||||||||||||||||--  0 [H] COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
|||-||||||||||--|-||-|||------------||----|||||-||-|-|||||||||-|||  0 [H] COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase
-||||-||-||||||---||||----|||-|-----||----||||||||--||||---|||||--  0 [EH] COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes
|||-|||||||||||-|||||---------------|------------|--|-------|-|---  0 [J] COG0182 Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family
-|||--|||-|||-----||-|---------------|--||||||||||||||||---|||||--  0 [HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)
------------------||||||--|||||||||-|||||||||||-||||||||--||||||--  0 [J] COG0219 Predicted rRNA methylase (SpoU class)
||-||||||||||---|-||-|----|||-------||----|||||-||||---|||||||||--  0 [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing
-------------|---|--------|---||-||-||-||-||||||||-|---|---|||||--  0 [G] COG0246 Mannitol-1-phosphate/altronate dehydrogenases
||||||--|||||---|-||||----||||-|----||----|||||-||||-||||||||||---  0 [C] COG0247 Fe-S oxidoreductase
--|--------|-|--||||||----|||||------|----|||||-||||||||||||||||||  0 [FP] COG0248 Exopolyphosphatase
------------|-|||-||||||--||||----|-|||||||||||||||||-||||||||||||  0 [E] COG0260 Leucyl aminopeptidase
|||---|||||||-----------------|-|||-|--||-|||-|-|-||--------------  0 [G] COG0269 3-hexulose-6-phosphate synthase and related proteins
||----||-||||-|---||------|---|-||--||||--|||-|-|-|-||||||--|-||--  0 [L] COG0270 Site-specific DNA methylase
--||||--|-|||||-|-||||----|||||-----||----|||||-||||||||||||||||--  0 [C] COG0277 FAD/FMN-containing dehydrogenases
|--|------||-||---||-|----|||||-||--||----|||||-||||||||||||||||--  0 [P] COG0288 Carbonic anhydrase
--|--------|-|--|-||||||--|||----|--|-----|||||-||||---|---||-|---  0 [G] COG0296 1,4-alpha-glucan branching enzyme
-|----||--||--|-||||||||------||-|--||----|||||-||||---|---||-|---  0 [G] COG0297 Glycogen synthase
---|---------||-||||||||--||||||-||-||----||||||||||||||||||||||--  0 [H] COG0307 Riboflavin synthase alpha chain
|||-|||||||||---||||-|-----||-|------|----||||||||||||||---|||||--  0 [R] COG0312 Predicted Zn-dependent proteases and their inactivated homologs
--|----------||-|-||-|----||||----|-||----||||||||||||||---|||||||  0 [S] COG0316 Uncharacterized conserved protein
---|------|||||-|-||-|||--||||----|-||----||||||||||||||---|||||||  0 [H] COG0320 Lipoate synthase
|||||||||||||||-||||||--||||||||||---|-|--||||||||||||||||||||||||  0 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs
-------------|||--||--||----------|-||----||||||||--|||----|-|-|--  0 [P] COG0369 Sulfite reductase, alpha subunit (flavoprotein)
--||----|----|----|--------||--------|----|||||-|---|--|---||-||--  0 [P] COG0376 Catalase (peroxidase I)
|||-----||----|-|-||||----|||-----|--||---|||||--||----||||||||---  0 [OK] COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase
|||||||||||||||-|-||-|||--|||||------|----|||||-||-|||||||||||||||  0 [H] COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases
--|----------|--|-||------|--|----|-||----|||||--|---|||---|||||--  0 [R] COG0385 Predicted Na+-dependent transporter
-------------||---||-|----||||------|-----|||||------------||-|---  0 [P] COG0387 Ca2+/H+ antiporter
-||-------------||||-------||-----|-|-----|||-|--------|----------  0 [R] COG0390 ABC-type uncharacterized transport system, permease component
-------------||---||------|----------|----|||-|-||--|--|---||--|--  0 [S] COG0397 Uncharacterized conserved protein
||-----|-||-----||||----|-|||-|--|--|-----|||||-||-|-||||||-||||--  0 [M] COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis
|||||||||||||||-||||-|----|---|--|---|----|||||--||||--|||||||||--  0 [FR] COG0402 Cytosine deaminase and related metal-dependent hydrolases
----||----||||||--||||----|||-----|-||----|||-|-||--||||||-||-||--  0 [E] COG0405 Gamma-glutamyltransferase
-|------|-|||----|||||----|------|---|----|||||--|-----|--|||||---  0 [E] COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
--|-|------|-||-|-||-------|||------|-----|||||--|-----|---||-||--  0 [Q] COG0412 Dienelactone hydrolase and related enzymes
-|--|||||||||||-||---|----|---|--|--||----||||||-|--||||||----|---  0 [E] COG0421 Spermidine synthase
||||---|||||----||||||----|||||-----||----|||||-||--||||--|||-||--  0 [H] COG0422 Thiamine biosynthesis protein ThiC
||||||||||||||||-----|--|||||||---|---||||------------------------  0 [J] COG0423 Glycyl-tRNA synthetase (class II)
--|---||-----||-||||||||--|||||-----||----|||||-||-|||||||||||||||  0 [D] COG0424 Nucleotide-binding protein implicated in inhibition of septum formation
||||||--||||----|||||-------------|-|-----||||||||||-|||--||||||--  0 [O] COG0425 Predicted redox protein, regulator of disulfide bond formation
|||---|||||||-|-||||-|-----||-|-----||----|||-|-||---------||-----  0 [S] COG0432 Uncharacterized conserved protein
|||||||||||||---||||-|-----||---|----|----||||---|-|---|---|||||--  0 [R] COG0433 Predicted ATPase
-----------------|||||||--||||||-|--||----|||||-|-||-------||-|---  0 [G] COG0448 ADP-glucose pyrophosphorylase
||-|--||||------||-|----||-||||-----||----------||-----||||-------  0 [D] COG0455 ATPases involved in chromosome partitioning
||||||||||||||||--||-|----||||------||-----------|-----|--|||-|---  0 [O] COG0464 ATPases of the AAA+ class
--|----------||-||--||||||----|-----||||||||||||||||||||||||||||||  0 [O] COG0466 ATP-dependent Lon protease, bacterial type
||-|--||-||--||-|-|--|||--|---|||||-||----|||||-||||||||||||||----  0 [P] COG0471 Di- and tricarboxylate transporters
||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||||||||||||  0 [C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit
--------|-------|----|-----||||||---|-----------------------------  0 [P] COG0490 Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels
|||------|---||-|||||--|--|||||---|-||----||||||||||||||||||-|||--  0 [H] COG0502 Biotin synthase and related enzymes
---|---------||---||-|----|||-----|-||----|||||--|-|-|||||||||||--  0 [E] COG0506 Proline dehydrogenase
--|----------||-|-||||----|||-----|-||----|||||-||--||||||-|||||--  0 [R] COG0523 Putative GTPases (G3E family)
-------||---|||-|-|--|-----||-|-----||----||||||||--|--|--|-||||--  0 [P] COG0529 Adenylylsulfate kinase and related kinases
||||||||||||-||-|||-----||-----------|----|||||-|--|--------|-----  0 [P] COG0530 Ca2+/Na+ antiporter
|||||||||||||---||||-|-----||-||--|-||-----------|-----|----|-|---  0 [R] COG0535 Predicted Fe-S oxidoreductases
---|||||--|-|-----|------------||||-----|-|||-|--||---------|-----  0 [E] COG0549 Carbamate kinase
||||||||||||------||-|-----||-|------|----|||||-||||||||---|||||--  0 [O] COG0555 ABC-type sulfate transport system, permease component
-|------|-|||----|||||----|------|---|----|||||--|-----|--|||||---  0 [E] COG0559 Branched-chain amino acid ABC-type transport system, permease components
-------------||------|||--||||----|-||----||||||||||||||---|||||||  0 [C] COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes
----|--||---|----||||-----|||-|---|--|-||||||-|-||--||||||||||||--  0 [R] COG0579 Predicted dehydrogenase
|-|||||||--||||---|-|--|--|------||-||----|||||-||||-||||||||||-||  0 [ER] COG0591 Na+/proline symporter
-||-----||-------|||||||--|---|--||-||----||||---|||---|---|||||--  0 [P] COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component
|||||||||||||---|-||----------|---|-||----|||||-||||||||||||||||||  0 [R] COG0603 Predicted PP-loop superfamily ATPase
|||||||||||||---|-||------||||------||----||||||||||||||--|----|--  0 [H] COG0611 Thiamine monophosphate kinase
||||----|--||---||||-|--------|------|----|||||-||||-|||----------  0 [R] COG0613 Predicted metal-dependent phosphoesterases (PHP family)
|||||||||||||---||||||-||-|||||---|-||----||||||||||||||||||||||||  0 [J] COG0621 2-methylthioadenine synthetase
-------------||---||-|----|||-----|-||----|||||-||-|||||---|||||||  0 [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
|-||||-----|-||---||-------||||------|----|||||-||-|||||---|||||||  0 [R] COG0661 Predicted unusual protein kinase
|||---||||------|||||------||-------||----|||||-||--||||||-|||||--  0 [G] COG0662 Mannose-6-phosphate isomerase
|||-||||-|-|----|-||-|----|||-|-----||----|||-|-||--||||--||||||||  0 [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily
||----||--|------|------------|---|-------|||||-||-||--|---||-|---  0 [M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase
-|-|----|-|||----|||||----|------|---|----|||||--|-----|--|||||---  0 [E] COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
|||-----||---|-------|----||||-------|----|||||-||||---|---||-|---  0 [H] COG0684 Demethylmenaquinone methyltransferase
||||----||---||-----||||---||||-----||----|||||-|||||||||||||||-||  0 [I] COG0688 Phosphatidylserine decarboxylase
-------------|||--||-|-----||-----|-||----|||----|-----||||-------  0 [R] COG0699 Predicted GTPases (dynamin-related)
------------------|-----------|-----||----|||-|-||-----|----------  0 [S] COG0700 Uncharacterized membrane protein
-||-----||---||--|||||||--|---|--||-||----||||--||||---|---|||||--  0 [P] COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components
|||||||||||||---|-||--||--|||||------|----||||||-|||||||||||||||||  0 [F] COG0717 Deoxycytidine deaminase
||||||||||||----||||----------|---|-||----|||||-||||||||||||||||||  0 [H] COG0720 6-pyruvoyl-tetrahydropterin synthase
--||||----|||||-|-||-|----|||||-----||----------||--||||||||||||||  0 [C] COG0723 Rieske Fe-S protein
-------------|----------------------|-----|||-|---|-|||-|||--|-|--  0 [G] COG0738 Fucose permease
--|-----|-|-|---|-||-|----||||----|-||----|||||-||||||||||||||||||  0 [O] COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component
-----------------|||||----|||||-----||-------|-||||||--|||||||||--  0 [E] COG0757 3-dehydroquinate dehydratase II
----------------|||||||||-|||||-----||----||||||||||||||||||||||--  0 [IM] COG0761 Penicillin tolerance protein
----------|-|---||||-------------||-||----|||||-||||||||||||||||||  0 [R] COG0780 Enzyme related to GTP cyclohydrolase I
|-|---|||-|-|---||||||--|-||||--||--||------------||----||-||||---  0 [O] COG0785 Cytochrome c biogenesis protein
------------------|-|-----|-------|-------|||||-|||--||-||--------  0 [E] COG0786 Na+/glutamate symporter
---|------------|-||-|----|||-------||----|||-|-|||||--|||||||-|--  0 [F] COG0788 Formyltetrahydrofolate hydrolase
-----------------|||----|-----||||--||----|||||-||||||||||-|||||--  0 [G] COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase
--------------|---||-|----|||-----|-|||----|||---||----|||-||||---  0 [E] COG0804 Urea amidohydrolase (urease) alpha subunit
----||--|----||-||||||||--||||||-||-||----||||||||||||||||||||||--  0 [H] COG0807 GTP cyclohydrolase II
----------------|||||||||-|||||-----||----||||||||||||||||||||||--  0 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis
--------------|---||-|----|-------|--||----||----||----|||-||||---  0 [O] COG0829 Urease accessory protein UreH
--------------|---||-|----|||-----|--||----|||---||----|||-||||---  0 [O] COG0830 Urease accessory protein UreF
--------------|---||-|----|||-----|-|||----|||---||----|||-||||---  0 [E] COG0831 Urea amidohydrolase (urease) gamma subunit
--------------|---||-|----|||-----|-|||----|||---||----|||--|||---  0 [E] COG0832 Urea amidohydrolase (urease) beta subunit
--|-------------||||||---|----|---|-||----|||||-||||||||||||||||||  0 [V] COG0841 Cation/multidrug efflux pump
--|---------------||-|-----||||------|----|||||-||--||||||||||||--  0 [P] COG0855 Polyphosphate kinase
-|||||----|----------|---||---|-----|-|----||-|---|---|-|||----|--  0 [V] COG1002 Type II restriction enzyme, methylase subunits
-|||---||--|----|-||------|||---|---||----|||||-||-||--|--||||||||  0 [M] COG1004 Predicted UDP-glucose 6-dehydrogenase
-------------||-|----|----|-------|-||----|||||-||--|--|--|-|-----  0 [C] COG1017 Hemoglobin-like flavoprotein
---|---------||-----||----|||-----|-||----||||||||--||||---|||||--  0 [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1
---------------------------||-------|-----|||||-||-----------|----  0 [Q] COG1021 Peptide arylation enzymes
---|------------|----|-----||--|----||---------------------|--|---  0 [G] COG1023 Predicted 6-phosphogluconate dehydrogenase
---|||--|-|||||-|--|||----|||||-|||-||----|||||-||--|--|---|||||||  0 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase
----||-----------|-|------|---|-----||----|||||-||||-||-||||-|----  0 [E] COG1027 Aspartate ammonia-lyase
--|-|||||-|-|---|-----------------|-||-----------|-----|----|-|---  0 [O] COG1030 Membrane-bound serine protease (ClpP class)
|||-|||||||||----|||||-----||-||-----|----|||-|-||------------|---  0 [C] COG1032 Fe-S oxidoreductase
-|||--||||-------|------||-----------|-----------|--------|-------  0 [R] COG1033 Predicted exporters of the RND superfamily
||||||--|||-|---||||||||---||||------|----|||||-|-------|||-------  0 [HR] COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes
-----------|-||---||------||||-------|----|||||--||--|||---|||||--  0 [C] COG1062 Zn-dependent alcohol dehydrogenases, class III
--|-||----|||||---||------||||-||||-||----|||-|--|--|||||||||||---  0 [R] COG1064 Zn-dependent alcohol dehydrogenases
||||||||||-------|------|-----|-----||----|||||-||||--------------  0 [O] COG1067 Predicted ATP-dependent protease
-------------|--------------------|-||----|||||------------||||---  0 [C] COG1069 Ribulose kinase
--------|----||---||-|----|---|---|-||-|--------||--|--|----------  0 [R] COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold
-|---------------|--|---|-|---|--||-||----------||-||||||||-||||||  0 [MG] COG1086 Predicted nucleoside-diphosphate sugar epimerases
|-|--||||--||-|---||||----|||||||---||----|||||--|||||||---||-||--  0 [M] COG1088 dTDP-D-glucose 4,6-dehydratase
|-||-||||--||---|-||||----|||||||---||----|---|--|--||||---||-||||  0 [M] COG1091 dTDP-4-dehydrorhamnose reductase
|||||-||||-|-||||||-|------||||---|---|||||||-|--|--|---|--------|  0 [L] COG1112 Superfamily I DNA and RNA helicases and helicase subunits
--------------------|-|||-|---|-|||-|-----|||||-||||--------------  0 [E] COG1114 Branched-chain amino acid permeases
--|---||------------|||||-|-----|||-||----|||-|-||||-||-|||-||----  0 [E] COG1115 Na+/alanine symporter
-||-||--||||-----|||||||--|---|--||-||----||||---||||--|---|||||--  0 [P] COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component
------------------||-------||--------|----|||||-||--||||||||||||--  0 [P] COG1118 ABC-type sulfate/molybdate transport systems, ATPase component
|||-|----|-|------|||-----||||----|-------|||||-|------|||-||-|---  0 [R] COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase
--|--|--------------|-||--------|-|--|||--|||||------------||||---  0 [EP] COG1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
-----------------|--|---|||----|----||-|--|||||-||||---|---|||||--  0 [G] COG1129 ABC-type sugar transport system, ATPase component
|--|||--|-|||-------||---------|----||----|||------|-||||||-------  0 [C] COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain
----------|-|-------------|||-----|-|-----|||-|--|-----|-----|----  0 [C] COG1140 Nitrate reductase beta subunit
|||-|||||||||----|||||--------|-----|-----|||||-|||||||||||||-|---  0 [C] COG1145 Ferredoxin
-----------------|--|-----|--|-|----||----|||||-||||---|---|||||--  0 [G] COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components
---|--||--|-|-----||||--|-|------|---|----|||||-||||-|||--|||||---  0 [P] COG1178 ABC-type Fe3+ transport system, permease component
-------------||-----|---------|---|-||----|||||-|||||||||||-------  0 [H] COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
||||----||---||-----|-||-|-||||-----||-----------|--|||||||||||-||  0 [I] COG1183 Phosphatidylserine synthase
|||---|||-|||---||--|-----------|----|----|||||----|--------------  0 [R] COG1203 Predicted helicases
|||---||||||-||----|-|----|||-------||-----||---------------|-----  0 [R] COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
|||||||||||||||||-||-|----|||||-----||-------||--|--||||--||||||--  0 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)
|-|||||||--||----|||-|----|||||||---||----|||||--|--||||---||-||--  0 [M] COG1209 dTDP-glucose pyrophosphorylase
--||||----|||||-||||-|----|||||---|-||----|||||-||||||||||||||||-|  0 [O] COG1225 Peroxiredoxin
|--||||-|--|-|---|--||-----||-|-|-|-||-------||-||-----|---|||||--  0 [Q] COG1228 Imidazolonepropionase and related amidohydrolases
------------------||-|----|||-------|------------|-----|------||--  0 [E] COG1231 Monoamine oxidase
--||------------|----|-----|||------||----||||||||-|-|||----------  0 [E] COG1246 N-acetylglutamate synthase and related acetyltransferases
---|||--|-|||-------||-----||||---|-||----|||||-||-----|---|||||||  0 [I] COG1250 3-hydroxyacyl-CoA dehydrogenase
--|-------------|----------||-|---|-||----|||||--|-----|---||-||--  0 [C] COG1251 NAD(P)H-nitrite reductase
--|-----------|---||--||---||-------||----------||-|||||---|||||--  0 [S] COG1262 Uncharacterized conserved protein
--------|------------------||-------||-----------|---------||-|---  0 [S] COG1273 Uncharacterized conserved protein
-|--|-|||----||-----------|||--||||-------|||-|-|-||-|------------  0 [P] COG1275 Tellurite resistance protein and related permeases
--------------------|-----|||-|---|-||----|||||-||-|---|||-|-|---|  0 [R] COG1279 Lysine efflux permease
|-|-||--|||||----||--|----|---------||----|||||-|||||--|--||||||--  0 [E] COG1280 Putative threonine efflux protein
--------------------|----|------|||-||----|||-|---|------------|--  0 [S] COG1288 Predicted membrane protein
---|||----||||--|-||-|----||||------||----------||--||||||||||||||  0 [C] COG1290 Cytochrome b subunit of the bc complex
|||---||||--|-----||-------||-|---|-||-----------|------------||--  0 [S] COG1300 Uncharacterized membrane protein
--||--||----|---|--||||||||||-|---|-||----|||||-||--|--|--|||-||||  0 [C] COG1301 Na+/H+-dicarboxylate symporters
----||-----------|------------||----||----|||||---|--------||||---  0 [G] COG1312 D-mannonate dehydratase
-----------------|------||----|------|----------|-----------------  0 [L] COG1315 Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain
-----------------|----||||----|-----||----||||||||-----||||---|---  0 [NU] COG1317 Flagellar biosynthesis/type III secretory pathway protein
----------|||--------|--||-||-------||----|||----|-----|---||-|---  0 [C] COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs
---------------------|--||||||------||---------------------|||||||  0 [K] COG1329 Transcriptional regulators, similar to M. xanthus CarD
|-||||--|-|||---|--|-|||---||-|-----|------------------------||---  0 [O] COG1331 Highly conserved protein containing a thioredoxin domain
----------------|-||------||||------||---------------|||----------  0 [O] COG1333 ResB protein required for cytochrome c biosynthesis
----------------||------------|-----||----------||------|||-------  0 [N] COG1334 Uncharacterized flagellar protein FlaG
|-------||-|----||-------------------|----------------------------  0 [L] COG1336 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily)
|||--|--||||-----|-||------||---|----|----------------------------  0 [L] COG1343 Uncharacterized protein predicted to be involved in DNA repair
--|---||------------||--------||--|-||----|||||-||||-|||-----|----  0 [M] COG1346 Putative effector of murein hydrolase
|||--||-||||----||---------||--------|----------------------------  0 [R] COG1353 Predicted hydrolase of the HD superfamily (permuted catalytic motifs)
--------|-------||-------------------|----------------------------  0 [L] COG1367 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily)
-|--||||-|--||--|-||-|-----|||------|-----------------------------  0 [L] COG1372 Intein/homing endonuclease
-----------------|||------|||||-----||----|||-|-||---|||---||||---  0 [S] COG1376 Uncharacterized protein conserved in bacteria
|||||||||||||--------|--------------|-----------------------------  0 [K] COG1378 Predicted transcriptional regulators
|||---||-|--------------------------||----------------------------  0 [S] COG1379 Uncharacterized conserved protein
--|---||------------||--------||--|-||----|||||-||||-|||-----|----  0 [R] COG1380 Putative effector of murein hydrolase LrgA
|-|---|---||----|-|--|-----------|--|-----|--|----------|||-------  0 [V] COG1401 GTPase subunit of restriction endonuclease
--||----|-|-|||||-||||----|||||-||--||||------|-||--||||--|||-|---  0 [O] COG1404 Subtilisin-like serine proteases
-----------------|------||----|------|----------|-----------------  0 [N] COG1406 Predicted inhibitor of MCP methylation, homolog of CheC
-----------------|||-|----|||||------|----|||||-|||-|--|---|||||--  0 [E] COG1410 Methionine synthase I, cobalamin-binding domain
|-||---------|||--||--||||--------|-||----||-----|------------|---  0 [C] COG1413 FOG: HEAT repeat
---|------------||---|----|||-------||----|||||-||||---|--||||||--  0 [K] COG1414 Transcriptional regulator
-|--------------|-----------------|-|-----------------------------  0 [H] COG1424 Pimeloyl-CoA synthetase
----||--|-|-|---|----|||-------------|------------------|||-------  0 [R] COG1427 Predicted periplasmic solute-binding protein
---------------------------------|--|-----|||-|---||----||--|---||  0 [M] COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases
|||---|||-|||---||-||-----------|----|----------------------------  0 [L] COG1468 RecB family exonuclease
||||||||||--|----|----------------|-||-----------|--||||----------  0 [S] COG1469 Uncharacterized conserved protein
--|---|||----------------------------|----------------------------  0 [S] COG1470 Predicted membrane protein
|---||--|-|||---||||----------|------|----|||||-||||-------|||-|--  0 [R] COG1489 DNA-binding protein, stimulates sugar fermentation
--|---------------||||----|||||-----||----|||-|-|-||---------|||--  0 [G] COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins
---------------------|||------------||----|||||-||||||||||||||||||  0 [O] COG1495 Disulfide bond formation protein DsbB
----------------|-||||||-||||||---|-||----|||||-||||||||--||||||||  0 [S] COG1496 Uncharacterized conserved protein
---|||||--|||||---|-||------------|-||-----------|--|------|---|-|  0 [E] COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases
-||-------------||--||--|-----------||----|||||-|-|||------||-||--  0 [E] COG1509 Lysine 2,3-aminomutase
-|----||--------------------------|-|------------------|---|-|----  0 [K] COG1510 Predicted transcriptional regulators
-----------------|||----|------|----||----|||----|-|---|-----|||--  0 [R] COG1512 Beta-propeller domains of methanol dehydrogenase type
|||-|||||||||---||-|-|----|---|---|-||----|||||--|-----|---|||||--  0 [J] COG1514 2'-5' RNA ligase
---||||||||||-|-||-|-|--------|-----|-----|||||-----|-------------  0 [L] COG1515 Deoxyinosine 3'endonuclease (endonuclease V)
||||--|||--------|---|---|-|||------|-----|||||-||--|--|-------|||  0 [S] COG1520 FOG: WD40-like repeat
|||||||||||||--------|----|||-|-----||----|||||-||||-|||---|||||--  0 [K] COG1522 Transcriptional regulators
--|--------|-----||-||||--|||-|-||--||-|--|||||-||||---|---||-|---  0 [G] COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases
||-|--||-|---||-|--|------|-------|-|--|||-------|||-||---|||||---  0 [L] COG1525 Micrococcal nuclease (thermonuclease) homologs
|-|-----|------|-|--------|||-|---|--||---|||||-|-||----|||-------  0 [P] COG1528 Ferritin-like protein
----------|||---|----|--|--||-------||----|||----|-----|---||-||--  0 [C] COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs
-||-|-|||||||----||-|------||-|-----||-----------|-----|---|||||-|  0 [L] COG1533 DNA repair photolyase
-----------------|------------------|-----|||-|-||-----------|----  0 [Q] COG1535 Isochorismate hydrolase
------||------------||----|--|----|-||----|||||-|||--|||--||------  0 [R] COG1540 Uncharacterized proteins, homologs of lactam utilization protein B
|-|-----|--|-------|||---------------|----|--|--|---|--|----------  0 [H] COG1541 Coenzyme F390 synthetase
------||----------||----|--||||------|----------------------------  0 [S] COG1543 Uncharacterized conserved protein
---|||----|||---|-||-|------------|-||----------------------------  0 [S] COG1547 Uncharacterized conserved protein
-----------------|------||----|-----||----|||||||||||---|||-------  0 [T] COG1551 Carbon storage regulator (could also regulate swarming and quorum sensing)
---|----|-----------||---------|----||----|||------|-||||||-------  0 [S] COG1556 Uncharacterized conserved protein
|--|-------|-||---||-|----|||-----|-|---------------||||---|||||--  0 [I] COG1562 Phytoene/squalene synthetase
----------------|-----------------|-|-----|||||-|||--|||---|||||||  0 [V] COG1566 Multidrug resistance efflux pump
----------------||------||----|-----||----|||||-||-----||||-------  0 [N] COG1580 Flagellar basal body-associated protein
-----------------|------||----|-----||----------------------------  0 [N] COG1582 Uncharacterized protein, possibly involved in motility
-|--|||||-|||---||------------|-----||----||||||-|--|--|----------  0 [E] COG1586 S-adenosylmethionine decarboxylase
|||----|||-|-----|-||---------|-----|---------------------|-------  0 [C] COG1592 Rubrerythrin
-----------------|--|---|-|----------|----|--||-||||-------||--|--  0 [G] COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
--------||-|----||-------------------|----------------------------  0 [L] COG1604 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily)
--|-||||||||-|--||-|||||--||||-|--|-||----|||||-||-|||||--||||||--  0 [R] COG1611 Predicted Rossmann fold nucleotide-binding protein
------------------||-------|||-------|----|||||--|--||||---|||||--  0 [P] COG1613 ABC-type sulfate transport system, periplasmic component
---|----||-|---------|---|--------|-||----|||-|-||||-||||||--|----  0 [C] COG1620 L-lactate permease
-------------||--|--------|---|-|||-||-----||---|--|---|---|------  0 [G] COG1621 Beta-fructosidases (levanase/invertase)
-----------------|--|-----|||-|-----||----------------------------  0 [R] COG1623 Predicted nucleic-acid-binding protein (contains the HHH domain)
|-|---||---|----||------------|-----||---------------------||||---  0 [S] COG1633 Uncharacterized conserved protein
----------------||--|---------|||-|---------------|||||-|||-----||  0 [S] COG1636 Uncharacterized protein conserved in bacteria
-----------------||-|---|-|---------||----|--||-||||---|---||-||--  0 [G] COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
------------------||-|--------------|-----||||---------|-----|----  0 [S] COG1649 Uncharacterized protein conserved in bacteria
--|------|---||---||----------------|-----------------------------  0 [I] COG1657 Squalene cyclase
|-||||||||--|---------------------|--------||-|-|----------||-|---  0 [R] COG1661 Predicted DNA-binding protein with PD1-like DNA-binding motif
----------------------||||----|-----|--------|--||--|--||||----|--  0 [M] COG1664 Integral membrane protein CcmA involved in cell shape determination
-------------------|-------||-------||----|||||-||||---|--|-------  0 [S] COG1666 Uncharacterized protein conserved in bacteria
--|-----------------|-----|---------|-------------||----||--------  0 [E] COG1687 Predicted branched-chain amino acid permeases (azaleucine resistance)
|||||||||||||--|||-|-|----|||-|------|----|||-|--|-----|----------  0 [S] COG1690 Uncharacterized conserved protein
-----------------|------||----|-----||------------------|||-------  0 [S] COG1699 Uncharacterized protein conserved in bacteria
---||||||--||--------|----||||-------|----|||----------|-------|--  0 [E] COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family
|||---|||||||---||------------|---|-----------|---|--------||----|  0 [R] COG1708 Predicted nucleotidyltransferases
----------||-||---||-|||--|||||------|--------------|-------------  0 [T] COG1716 FOG: FHA domain
-----------------|------||----|-----||----------------------------  0 [S] COG1728 Uncharacterized protein conserved in bacteria
----------------|-----||||----|-----||----||||||||||||||--||||||||  0 [T] COG1734 DnaK suppressor protein
--||----|-|-|----|--||||-||-------|-|-----|||||-||||-||----||||---  0 [S] COG1738 Uncharacterized conserved protein
--|---------------|--------||-----|-||----|||-|--|-----|---||-||--  0 [S] COG1742 Uncharacterized conserved protein
----|||-|-|-|||---||-|-----------|---|----------|--|----|||||||---  0 [E] COG1748 Saccharopine dehydrogenase and related proteins
-------------||||||-|---|--|||-|----||----|||-|-||--||||---|||||||  0 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily
---------------------|-----||---|||-||------------||-||-----------  0 [S] COG1755 Uncharacterized protein conserved in bacteria
---|--||----|-------|----|----|---|-||-------||-|-||-||-|||-------  0 [C] COG1757 Na+/H+ antiporter
---------------------|----||||-||||-|--||||||||------------|-|----  0 [F] COG1780 Protein involved in ribonucleotide reduction
--||---|-----||--|-|-|----|-------|-||----||||---|--|--|-----|----  0 [P] COG1785 Alkaline phosphatase
-----------------||--|---------------|------------------||--------  0 [V] COG1787 Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes
--------|--|--------||----|||-|-|---||----|------||----|||-|||||-|  0 [I] COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit
-------------||-|--|----------------|------------|--|-------------  0 [S] COG1791 Uncharacterized conserved protein, contains double-stranded beta-helix domain
|||||||||||||||||----------||-------||----------|||--||---|||-||--  0 [L] COG1793 ATP-dependent DNA ligase
------|||----------------------|----|-----|||||----|---|--|||-||--  0 [M] COG1794 Aspartate racemase
------|||-------|-|||---------|-----|-----|||||--|--||||---|||||--  0 [M] COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
||-------|----------------|---------|-----------------------------  0 [S] COG1809 Uncharacterized conserved protein
|||------|---|----|--|-----||||-----|------||||-||------------|---  0 [GC] COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
-------------------------|--------|-|-----|||||-|-||------|-------  0 [R] COG1823 Predicted Na+/dicarboxylate symporter
--|---------|-----||-------||-|-----||-----------|----------|-|---  0 [E] COG1834 N-Dimethylarginine dimethylaminohydrolase
|||||||||-|-------||-----------------|----------------------------  0 [S] COG1836 Predicted membrane protein
|||---|||||-----||------------|------|----|||||-||--||||-----||---  0 [C] COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain
--||------|-|-----|||-----|-----|||--|-----||||-||||||||--|||||---  0 [P] COG1840 ABC-type Fe3+ transport system, periplasmic component
-||---|||---------||----------------|-----------------------|-|---  0 [G] COG1850 Ribulose 1,5-bisphosphate carboxylase, large subunit
-|------------------|---|-----|-----|--------------------------|--  0 [M] COG1861 Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog
-||||||||||||-----------------------||----------------------------  0 [S] COG1865 Uncharacterized conserved protein
------------||------||------------|-||----|||||-||||------|||||---  0 [C] COG1866 Phosphoenolpyruvate carboxykinase (ATP)
-----------------|--------|----|--|-||-|--|||||-|-||--------------  0 [G] COG1869 ABC-type ribose transport system, auxiliary component
--||--|||--------|-------|----|-----||----------||-----|---||--|--  0 [NT] COG1871 Chemotaxis protein; stimulates methylation of MCP proteins
||||||||||--------------------|-----||----------------------------  0 [S] COG1873 Uncharacterized conserved protein
------||---------|------------|--|--||-------|------|-------|--|--  0 [G] COG1874 Beta-galactosidase
-----------------|----||--||||------||----------||--|--|----------  0 [T] COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH
||||||-||-||-----|||------|||-----|--|-----------|||---|---||-|---  0 [R] COG1878 Predicted metal-dependent hydrolase
--|--------------|--|---|-|--|||----||----|||||-||||---|---|||||--  0 [G] COG1879 ABC-type sugar transport system, periplasmic component
|-|||||||--|-|--|-----||--|||||---|-|-|---|||-|-|--|||||||-||-|--|  0 [R] COG1881 Phospholipid-binding protein
---||||||--||--------|----||||-------|----|||----------|---|||||--  0 [I] COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit
-----------------|------------||-|--||----|||||-|---------||||----  0 [E] COG1897 Homoserine trans-succinylase
|-|--||||--||-----||||----|||||||||-||----|---|--|-|||||--||||||--  0 [M] COG1898 dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes
-----------------|--------|---||----||----|||||-------------||||--  0 [G] COG1904 Glucuronate isomerase
-|||||--|-|-------------------|-----|------------------|----------  0 [P] COG1910 Periplasmic molybdate-binding protein/domain
--||||-----|-----|-|||------|-|--|---|----|||||-|||--|||||----||--  0 [L] COG1943 Transposase and inactivated derivatives
|||---|||||-----||------------|------|----|||||-||--||||-----||---  0 [C] COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain
-----------||||---------------------|-----|||||--|-----|----||||--  0 [FH] COG1953 Cytosine/uracil/thiamine/allantoin permeases
-----------|-||----|-|----|||-----|--|----|||-|--|-|---|--||||||--  0 [F] COG1957 Inosine-uridine nucleoside N-ribohydrolase
---|||--|-||||-----|||----|||||---|-||----|||||-||---|||---|||||--  0 [I] COG1960 Acyl-CoA dehydrogenases
--|----|--|-|---|---|-----|||-||----||----|||||-||||-||||||-------  0 [T] COG1966 Carbon starvation protein, predicted membrane protein
|--------|||----||||||---||||||||||-||----||||||||--||||--||||||--  0 [V] COG1968 Uncharacterized bacitracin resistance protein
|-|-----------------|-----|---|-----||----|||||--|--|||---|-------  0 [S] COG1971 Predicted membrane protein
-------------------|------------|-|-||----|||||-|-||----||-----|--  0 [F] COG1972 Nucleoside permease
----------|||--------|-----||-------||----|||----|-----|---|||||--  0 [O] COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family
----------------||------------|-----|-----------------------------  0 [S] COG1978 Uncharacterized protein conserved in bacteria
------||-----|------||----||||----|-||----|||||-|||--|||--||---|--  0 [E] COG1984 Allophanate hydrolase subunit 2
||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||--  0 [H] COG1985 Pyrimidine reductase, riboflavin biosynthesis
||--||--|||||------------------------|----|||||-|-----------------  0 [S] COG1986 Uncharacterized conserved protein
----------------|-|||----------------|----|||||-||-|||||||||||||--  0 [H] COG1995 Pyridoxal phosphate biosynthesis protein
---|------|-|||-|----|--------------||----------||--||||--||||||||  0 [R] COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems
---|||--|-|-|||------|||---|||----|-||----|||||-||--||||||||||||||  0 [C] COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit
--|-----|---------||-|----||||------||----------||---|||||||||||--  0 [C] COG2010 Cytochrome c, mono- and diheme variants
----------------|-||||----|||||-----||----|||||-||--||||--||||||--  0 [H] COG2022 Uncharacterized enzyme of thiazole biosynthesis
---|||--|-|||||--|--||----|||||-----||----|||-|--|--||||---|||||--  0 [C] COG2025 Electron transfer flavoprotein, alpha subunit
--|---------------||-|----||||------|-----|||||-||||||||----------  0 [M] COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)
---|----|--|-||-----||----||||----|-|-----|--||-||-----|---|||||--  0 [I] COG2030 Acyl dehydratase
--------|---|-------|-----|-----|----|----|------||-----||--------  0 [I] COG2031 Short chain fatty acids transporter
--|----------||-|----|-----||||-----|-----|||||-|--|-|||----||-|--  0 [P] COG2032 Cu/Zn superoxide dismutase
|--|-------------|--|---|||-----|||--|----------|-----------------  0 [S] COG2035 Predicted membrane protein
|||||||||||||-----||||----|||||------|----|||-|-||-----|---|||||--  0 [H] COG2038 NaMN:DMB phosphoribosyltransferase
------||---|--------||-----||---|||-||-------|---------|----------  0 [O] COG2039 Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)
-------------||---|--------||||-----|-----|----------------|--|---  0 [E] COG2040 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)
--||||--|-|||---|--|-|----|||-------|-----|||||--|-|---|--||||||--  0 [R] COG2041 Sulfite oxidase and related enzymes
||--||---|-------|||-|--------|-----|------------------|----------  0 [HR] COG2045 Phosphosulfolactate phosphohydrolase and related enzymes
-------||-|||||-|-||-|--------------||--------------------|-------  0 [P] COG2046 ATP sulfurylase (sulfate adenylyltransferase)
------||-----|------||----||||----|-||----|||-|-|||--|||--||---|--  0 [E] COG2049 Allophanate hydrolase subunit 1
-----------------|||----------|-----||----------------------------  0 [S] COG2052 Uncharacterized protein conserved in bacteria
||----||-|----------------|---|-----|-----|||-|--|||-------||||---  0 [C] COG2055 Malate/L-lactate dehydrogenases
--------------------|-------------|-||----------||||-||-|||-------  0 [R] COG2056 Predicted permease
-----------|--------||----|||-|-|---||----|------||----|||-|||||-|  0 [I] COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit
-|---------------|||||---||---------||-|--------||-----|---||-||--  0 [P] COG2059 Chromate transport protein ChrA
------------------|||-----|---------||----|||||-||-----|---|||||--  0 [E] COG2066 Glutaminase
|--------||||--------|-----||-------||----|||----------|---||-||--  0 [R] COG2068 Uncharacterized MobA-related protein
-------------||---|--|----||||------||-----------|-----|---||-||--  0 [P] COG2072 Predicted flavoprotein involved in K+ transport
|---||----||||------------|||-------||----|||-|--|-----|---||-|---  0 [R] COG2079 Uncharacterized protein involved in propionate catabolism
----------|||--------|--||-||-------||----|||----|-----|---||-||--  0 [C] COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs
---|||--|-|||||--|--||----|||||-----||----|||-|--|--||||---|||||--  0 [C] COG2086 Electron transfer flavoprotein, beta subunit
-||-----------------|---|-----|-----|----------------|--|||----|--  0 [M] COG2089 Sialic acid synthase
-------------||---||----------|---|-||----|||-|---|||--|----------  0 [H] COG2091 Phosphopantetheinyl transferase
-||-|||||||||---|--|-||||-----------|-----||||||||-|||||--||||||--  0 [U] COG2095 Multiple antibiotic transporter
------------------||-|--------||--|-||----|||||-|-||--------|-|---  0 [R] COG2103 Predicted sugar phosphate isomerase
|-|||||||-------|-||||----|||||-----||----||--|-||--||||--||-|||--  0 [H] COG2104 Sulfur transfer protein involved in thiamine biosynthesis
-||---|---||------||-|--------------||----|||||-||-----|----------  0 [S] COG2105 Uncharacterized conserved protein
----||--|-|||---|----|||-------------|------------------|||-------  0 [R] COG2107 Predicted periplasmic solute-binding protein
-----------------|-------------|----||----|||||---|--------||||---  0 [G] COG2115 Xylose isomerase
--|---||-|-|-|||-----|----||||----|-||----|--|-------------||||---  0 [S] COG2120 Uncharacterized proteins, LmbE homologs
---|---------||---||-|----|||||-----||-----------|--|--|--||||||--  0 [Q] COG2124 Cytochrome P450
--|-----|----------|-|----|||||--||-||----|||||--|---|||---|||||--  0 [S] COG2128 Uncharacterized conserved protein
---|---------||----|--------------|-|-----|||-|--|-----|------||--  0 [R] COG2130 Putative NADP-dependent oxidoreductases
---|------|--||-|--|------|||-------||----|||||--|||||||--||||||--  0 [Q] COG2132 Putative multicopper oxidases
----------|-------||-|---|-|||-------|----|||-|--|--|--|---||-||--  0 [G] COG2133 Glucose/sorbosone dehydrogenases
---|---------|-----|------||||------|-----|||-|--|---------||||---  0 [S] COG2135 Uncharacterized conserved protein
||||----||||------||-|----|||-----|-||-----------------|----------  0 [S] COG2138 Uncharacterized conserved protein
--|---|||---------|-----------------|---------|--------|---||-|---  0 [GR] COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzymes
--||||----||--|---||-|----||------|-||----|||||--|--|--|---||-||--  0 [PR] COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases
---|-------------|||||----|---|--||-||----|||-|-||||||||--||||||--  0 [M] COG2148 Sugar transferases involved in lipopolysaccharide synthesis
--------------|---|-------|||--|-----|----|||-|-||-----------|----  0 [R] COG2153 Predicted acyltransferase
--|-------------------||------|-----||----------------------|-|-|-  0 [S] COG2155 Uncharacterized conserved protein
-----------------|------------|-----||----|||||-------------|-----  0 [G] COG2160 L-arabinose isomerase
---|-------------|||-------||----||-------|||-|-|----------|-----|  0 [D] COG2161 Antitoxin of toxin-antitoxin stability system
---------------------------||-----|-||----|||-|--|------------||--  0 [Q] COG2162 Arylamine N-acetyltransferase
||----||-|||||||--------------|------|----------------------------  0 [J] COG2163 Ribosomal protein L14E/L6E/L27E
--------|-|-|-------------|||-----|-|-----|||-|--|-----|-----|----  0 [C] COG2180 Nitrate reductase delta subunit
--------|-|---------------|||-----|-|-----|||-|--|-----|-----|----  0 [C] COG2181 Nitrate reductase gamma subunit
---||||||--||-------||----||||-------|----|||----------|---|||||--  0 [I] COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)
--||--|||--------|-|----||----|-----||----|||||-||--|--|--|||-||--  0 [NT] COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain
|-||----|-----|-||||-|-----||||---|-||----|||---||-----|---|||||--  0 [T] COG2203 FOG: GAF domain
----------------|---|-||||-----------|----|||||-||-|||||||||||||||  0 [T] COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
----------------||-|-|--||----|------|----------||-----|---|--|---  0 [T] COG2206 HD-GYP domain
--||||--|-||----|---|-------------|-|-----------------------------  0 [S] COG2210 Uncharacterized conserved protein
------------------|||---------||----|-----|||||----------------|--  0 [G] COG2211 Na+/melibiose symporter and related transporters
----------------|---------||||----|-||----|||-|--|-----|----||-|--  0 [P] COG2223 Nitrate/nitrite transporter
-----------|-||------|----||||-------|----|||||-||-----|---|||||--  0 [C] COG2224 Isocitrate lyase
----------||-|-------|----||||-------|----|||||-||-----|---|||||--  0 [C] COG2225 Malate synthase
|-||--||||---||-|--|-------||-|-----||----|||-|-||--|----------|--  0 [R] COG2234 Predicted aminopeptidases
|----------------||||-|||||||-|---|-||||-----|--||--|||----|||||||  0 [P] COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain)
-|----||----------------------------|-----------------------------  0 [M] COG2247 Putative cell wall-binding domain
-----------------|------|-----|-----||-----------|------|||----|--  0 [S] COG2257 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB
---|-------|-||----|-|----||||----|-||----|||||-||||-|||---|||||--  0 [S] COG2259 Predicted membrane protein
-------------------|-|----||||-||||-|-----|||||--|-----|---|||||--  0 [S] COG2261 Predicted membrane protein
------------------||------|----|----||----|||-|--|------------|---  0 [S] COG2268 Uncharacterized protein conserved in bacteria
----------------------||-------||-|-|-----|||||-||||------|-----||  0 [G] COG2271 Sugar phosphate permease
--------------|------|----|||-|---|-|---------|--------|-------|--  0 [I] COG2272 Carboxylesterase type B
-------------||--|---------||-|-----||---------------------||-||--  0 [G] COG2273 Beta-glucanase/Beta-glucan synthetase
------------------||----------||-|--||||||-||||-||--||||----|-||--  0 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
||-|-----|---------|-|-----|||----|-------||||---|-----|--||||||--  0 [E] COG2303 Choline dehydrogenase and related flavoproteins
--|-----|--||-----||||---|||||------||----|--||-||------------|---  0 [R] COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain
------||-------------|----|||-----|-------------------------------  0 [S] COG2306 Uncharacterized conserved protein
------------------|--|--------|-----|------|||--------------------  0 [T] COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1
---|-----------------|----|---------||----|||||-----|----------|--  0 [S] COG2311 Predicted membrane protein
---|-----------------|-----||-------||----------------------|--|--  0 [R] COG2312 Erythromycin esterase homolog
-||---------------||-|---|-||--|--|-||-----------|-----|----------  0 [S] COG2314 Predicted membrane protein
------------------|--|--------------||-----------|---------||||---  0 [S] COG2318 Uncharacterized protein conserved in bacteria
--||-----------------|-----|||------||----------||----------------  0 [S] COG2320 Uncharacterized conserved protein
-------------------|||--------||-|--||----|||-|-------------|-----  0 [S] COG2323 Predicted membrane protein
--|---------------|-||--------------||----|||||-||---|||---|||||--  0 [R] COG2334 Putative homoserine kinase type II (protein kinase fold)
-------------------|-|---------------|----|||--------|||---|------  0 [T] COG2336 Growth regulator
----||------------||-|----||||-------|-------|--|-----------------  0 [K] COG2345 Predicted transcriptional regulator
------------------|--|----||||----|-||-----------------|--||||||--  0 [R] COG2346 Truncated hemoglobins
--|------------------|--||------|||-------------------------------  0 [V] COG2348 Uncharacterized protein involved in methicillin resistance
------------------||||----|---|-----|-----|||||-||||-|||---|||||--  0 [S] COG2350 Uncharacterized protein conserved in bacteria
--------------|------|--------------||----|||-|--|-----|--||||||--  0 [R] COG2351 Transthyretin-like protein
---------------------|--------------|-----||||||||----------------  0 [L] COG2356 Endonuclease I
---|----|---|-----|--|---------------|----------||-|--------||--||  0 [R] COG2358 TRAP-type uncharacterized transport system, periplasmic component
-----------------|---|--------|-----||----------------------------  0 [S] COG2359 Uncharacterized protein conserved in bacteria
---------------------|----|---|-----||------------||--------------  0 [S] COG2364 Predicted membrane protein
--------|-||---------|--------------||-------||--|-|--------------  0 [Q] COG2368 Aromatic ring hydroxylase
------------------||-|----|-------|--||----|||---||----|||-||||---  0 [O] COG2371 Urease accessory protein UreE
------------------||||--------|-----||----------------------------  0 [D] COG2385 Sporulation protein and related proteins
---|||---|||-----|---|------------|-------|||||-||--|--|--|||||---  0 [R] COG2391 Predicted transporter component
--||-------||-------|---------------|-------------------|||-------  0 [R] COG2404 Predicted phosphohydrolase (DHH superfamily)
|-||||--|||||||-----------|-------|----------|---|-----|---||||---  0 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog
------|||---|------------------------|----------------------------  0 [S] COG2426 Predicted membrane protein
|||----||-|-----|-----------------|-||----------------------------  0 [S] COG2445 Uncharacterized conserved protein
-------||--------|--|---------||-|---|----------------------------  0 [S] COG2461 Uncharacterized conserved protein
-------------------|------------|-|---|-----------||----||--------  0 [R] COG2503 Predicted secreted acid phosphatase
--|---||||||-----||-|---------||-----|----------|--------------|--  0 [R] COG2509 Uncharacterized FAD-dependent dehydrogenases
------------------||--------------|-|------------|-----|--||--|--|  0 [V] COG2602 Beta-lactamase class D
--|-----------------|-----|---|-|-|-||----|||||-||||-|||----------  0 [GE] COG2610 H+/gluconate symporter and related permeases
------------------|-----------|-----||-----------|-----|----------  0 [R] COG2715 Uncharacterized membrane protein, required for spore maturation in B.subtilis.
---|--------------------------|-----||----|||||-||----------|-|---  0 [S] COG2718 Uncharacterized conserved protein
---|--------------------------|-----||----|||||-||----------|-|---  0 [S] COG2719 Uncharacterized conserved protein
---------------------|----|---|-----||-----------|----------------  0 [V] COG2720 Uncharacterized vancomycin resistance protein
----|------|------------------|-----||----|||||--------|--||||||--  0 [G] COG2721 Altronate dehydratase
------||-----||--|-|----------|-----||--------------|--|----------  0 [G] COG2730 Endoglucanase
------------------------------|-----|-----|||||------|------------  0 [K] COG2732 Barstar, RNAse (barnase) inhibitor
----------------||------------|-----||----|||||-||-----|----------  0 [KNU] COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor)
---|--------------------------|-----||----|||||-||----------|-|---  0 [T] COG2766 Putative Ser protein kinase
--|-----|-------|-||-|--------------|-----------||-----|---||-|---  0 [T] COG2770 FOG: HAMP domain
-------------|-------|--------------||-----------|--|--|------||--  0 [K] COG2808 Transcriptional regulator
---------------------|--------|--|--|------||-|--|---|----||---|--  0 [R] COG2819 Predicted hydrolase of the alpha/beta superfamily
--------------------------|||--|-|---|-|--|||--------|||---||--|--  0 [L] COG2826 Transposase and inactivated derivatives, IS30 family
------------------------------------|-----|||---||--||||---||-|---  0 [S] COG2828 Uncharacterized protein conserved in bacteria
--------------------||-----------||-------|||-|-||||-||----|||----  0 [S] COG2832 Uncharacterized protein conserved in bacteria
-|||----|-------|----|--||----|-----||----|||||-||||||||||||||||||  0 [M] COG2834 Outer membrane lipoprotein-sorting protein
-------------------|-|------------|-||---------------||-----------  0 [S] COG2839 Uncharacterized protein conserved in bacteria
------------------------------|---|-------|||||---|--|||----|-----  0 [D] COG2846 Regulator of cell morphogenesis and NO signaling
--------------------|-||------------|--------||--|---||---|-------  0 [S] COG2849 Uncharacterized protein conserved in bacteria
------------------------------------|-----|||||--|||||||----------  0 [S] COG2850 Uncharacterized conserved protein
--------------------------|-----|-|-||-----------|--|||---|-------  0 [C] COG2851 H+/citrate symporter
-------------||-|-------------------||----------||--||||||||||||||  0 [C] COG2857 Cytochrome c1
---|------||---------|----|----||---||----|||||-||||---|--||||||--  0 [S] COG2860 Predicted membrane protein
-------------------------|-----------|----|||-|--|||------|||-||--  0 [S] COG2861 Uncharacterized protein conserved in bacteria
--|----------||---|-----------------||----|||||--|---|||-------|--  0 [E] COG2866 Predicted carboxypeptidase
--|-||||--||||---|--||--------|------|----------||-----|---||||---  0 [R] COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain
-----------------|------|-----|-----||----||||||||-----|----------  0 [NUO] COG2882 Flagellar biosynthesis chaperone
|--|------|||||-|--|-|----||||-------|----|||||-||-----|---|||||--  0 [P] COG2897 Rhodanese-related sulfurtransferase
--------|-------|---------|----------|----------||----------------  0 [T] COG2905 Predicted signal-transduction protein containing cAMP-binding and CBS domains
---|---------------||-||-------------|-----------|--||||---||-|---  0 [S] COG2928 Uncharacterized conserved protein
--------------------|----------||-|--------|--|--||||||----|||||--  0 [K] COG2932 Predicted transcriptional regulator
------------------------------------|-----------|---|||-----------  0 [L] COG2946 Putative phage replication protein RstA
--||--------------||-------||--------|----|||||-|---|------|||||--  0 [S] COG2968 Uncharacterized conserved protein
--------------------|-----|-------|--|----||||--|--|-||--------|--  0 [H] COG2978 Putative p-aminobenzoyl-glutamate transporter
---|||--------------||----------|-|-||-------||-||-----|---|||||--  0 [E] COG2986 Histidine ammonia-lyase
---|||--------------||----------|-|-||-------|--||-----|---|||||--  0 [E] COG2987 Urocanate hydratase
------------------||------|-------|-------|||||-|--|--------------  0 [G] COG3001 Fructosamine-3-kinase
----------------|-----------------|-|-----------|-----------------  0 [S] COG3002 Uncharacterized protein conserved in bacteria
------------------||--------------|-||-------|--||--|--|------||--  0 [S] COG3011 Uncharacterized protein conserved in bacteria
--------------------|---------------||----|||-|-||----------------  0 [E] COG3048 D-serine dehydratase
--|---------------|------------|--|-|---------|-|----------|-||---  0 [M] COG3049 Penicillin V acylase and related amidases
--------------------|-----|----------|----|--||-||||-------||--|--  0 [G] COG3090 TRAP-type C4-dicarboxylate transport system, small permease component
-----------------|------------|-----||----||||||||-----|----------  0 [N] COG3144 Flagellar hook-length control protein
---------------------|----|---------|-----|||||--|--|-------------  0 [S] COG3162 Predicted membrane protein
-------------------||-----|-------|-||----|||-|-||---------||-|---  0 [R] COG3180 Putative ammonia monooxygenase
--------------------|-----|---------||--------|-||-|---|---||-----  0 [S] COG3181 Uncharacterized protein conserved in bacteria
--------------------------|-------|--|----------||---|||---|---|--  0 [S] COG3182 Uncharacterized iron-regulated membrane protein
----||-----|--------------|||-----|-------|||-|--|-----|---||||---  0 [S] COG3189 Uncharacterized conserved protein
----------------------||------------||----||||||||-----|----------  0 [N] COG3190 Flagellar biogenesis protein
---------------------|----|---------||-----------|-----|---|||||--  0 [S] COG3195 Uncharacterized protein conserved in bacteria
-------------------|-------||||-----||-------|---|-----|---|--|---  0 [Q] COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis
-------------------|-----------------|----------||--------|||-||--  0 [R] COG3211 Predicted phosphatase
---|------|--------||-----|||--|--|--|----||||--||---------||-||--  0 [P] COG3221 ABC-type phosphate/phosphonate transport system, periplasmic component
--|----------------|----------|---|-|-----------||----------------  0 [E] COG3227 Zinc metalloprotease (elastase)
------------------||-------||-------|------------|-----|----|-||--  0 [I] COG3239 Fatty acid desaturase
-----------|-----|-------------|||---|----||||------|------||-----  0 [G] COG3250 Beta-galactosidase/beta-glucuronidase
---------------------------||-------|------|--|--|-----|---|------  0 [S] COG3251 Uncharacterized protein conserved in bacteria
----||--|-|||---|--------------------|-----------|------------||--  0 [I] COG3255 Putative sterol carrier protein
--------------------|----------------|----|||-|-||---------|--|---  0 [P] COG3263 NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain
--------------------|-------------|-|-----|||||-|-----------|-----  0 [T] COG3275 Putative regulator of cell autolysis
-------------------|----------|-----||----|-----||-----|---|||||--  0 [QK] COG3284 Transcriptional activator of acetoin/glycerol metabolism
---------------------------||-------||-----------|---------||-|---  0 [L] COG3285 Predicted eukaryotic-type DNA primase
--------------------------|-----|---||----|||-|-|-----------------  0 [T] COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism
|||---|-|---|------------------|-----|----------|-----------------  0 [R] COG3291 FOG: PKD repeat
------------------||-|------------|--------------|----------------  0 [S] COG3296 Uncharacterized protein conserved in bacteria
------------------|-----------------|---------|--|-----|---||-||--  0 [T] COG3300 MHYT domain (predicted integral membrane sensor domain)
-----------------||||---------|--||-------|||||-||||||||||-|||||||  0 [M] COG3307 Lipid A core - O-antigen ligase and related enzymes
--------------------|---------|---|-||----|||-|-|-----------|-----  0 [S] COG3314 Uncharacterized protein conserved in bacteria
--|----------------||------|||------|-----------||-|--------|-|---  0 [Q] COG3315 O-Methyltransferase involved in polyketide biosynthesis
----------------------||------------|-----|||-|-||---||-----------  0 [R] COG3318 Predicted metal-binding protein related to the C-terminal domain of SecA
-------------------|------||||------|-----|||||--|-----|-----||---  0 [Q] COG3319 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases
-------------||----|-------|||----|--------------|---------|------  0 [Q] COG3320 Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes
-------------------|------|||||-----|--------|---------|---||-|---  0 [Q] COG3321 Polyketide synthase modules and related proteins
--|-----------------------|||--------|--------|-||-|---|---|||||--  0 [R] COG3324 Predicted enzyme related to lactoylglutathione lyase
-----------|---------------||--------|----|-----------------|-----  0 [K] COG3327 Phenylacetic acid-responsive transcriptional repressor
--|-||-----|------|--------||-||-----||----||||--------|----|-|---  0 [L] COG3328 Transposase and inactivated derivatives
------------------||-------||--------|-------------------------|--  0 [R] COG3329 Predicted permease
-----------------|||----------|------|----------------------------  0 [S] COG3330 Uncharacterized protein conserved in bacteria
-------------|-----------------------|-----------|-----|----------  0 [S] COG3332 Uncharacterized conserved protein
--------------------|-----|----------|--------|-||-|---|---||-----  0 [S] COG3333 Uncharacterized protein conserved in bacteria
----------------|-------------------||------------------||||||||--  0 [S] COG3334 Uncharacterized conserved protein
--|--|--|--|------||-|----|------|---|-----||-|-------||----|-|---  0 [L] COG3335 Transposase and inactivated derivatives
---------------------|----||||------||----------------------|-|---  0 [S] COG3336 Predicted membrane protein
--------|-------|--------------------|----------------------------  0 [L] COG3337 Uncharacterized protein predicted to be involved in DNA repair
|-|---------------||----------|-----||-----------------|---|||||--  0 [S] COG3339 Uncharacterized conserved protein
-------------||--|------------|------|----------------------------  0 [R] COG3341 Predicted double-stranded RNA/RNA-DNA hybrid binding protein
---|------|||------------------------|-----------|----------------  0 [S] COG3342 Uncharacterized conserved protein
--|----------|----|||------||-|---|--|----|--||-||----------|-----  0 [L] COG3344 Retron-type reverse transcriptase
-----------------|---------------|---|-------|--|-----------------  0 [G] COG3345 Alpha-galactosidase
----|-------------|-----------------||-------|-------------||-|---  0 [S] COG3347 Uncharacterized conserved protein
|-||--------------------------|-----||----------------------------  0 [L] COG3359 Predicted exonuclease
---|-----------------------||-------|-----------------------------  0 [S] COG3361 Uncharacterized conserved protein
----|------|--|------------||-----|----------||--------|||--------  0 [P] COG3376 High-affinity nickel permease
--|-||--|---------------------------||----------------------------  0 [S] COG3377 Uncharacterized conserved protein
---------||||-----------------|||---||--------|--|-----|------|---  0 [S] COG3382 Uncharacterized conserved protein
--||-|-----|------||-|---------------|----|------------|----|-----  0 [L] COG3385 FOG: Transposase and inactivated derivatives
----||-----|-|-------|------------|-|---------|--|-||--|---|||||--  0 [G] COG3386 Gluconolactonase
--|-|------|-------|-|--||-||-|-----||----|||-|--|-----|----|-|---  0 [S] COG3391 Uncharacterized conserved protein
--------------------|----------------|------------------|||-------  0 [L] COG3392 Adenine-specific DNA methylase
------------------|||----------------|----|--||---||-------||||---  0 [S] COG3395 Uncharacterized protein conserved in bacteria
-----------|---------|---------------|----|------------|----|-----  0 [S] COG3396 Uncharacterized conserved protein
------------------------------------||------------------|||-------  0 [R] COG3401 Fibronectin type 3 domain-containing protein
---|-----------------|--------------|-----------------------------  0 [S] COG3403 Uncharacterized conserved protein
----------------|--------------------|----|||-|------------|------  0 [G] COG3405 Endoglucanase Y
--|-||||---|-|-----|-|---------------|----------------------|-|---  0 [G] COG3408 Glycogen debranching enzyme
--|---------------||-|----|||||-----||----------|------|---||||---  0 [M] COG3409 Putative peptidoglycan-binding domain-containing protein
----|------|-|-----------------------|----------------------------  0 [S] COG3410 Uncharacterized conserved protein
---|------------||||-|---------------|-----------------|----------  0 [C] COG3411 Ferredoxin
---|----|--|-------|-|---------------|----------------------|-|---  0 [L] COG3415 Transposase and inactivated derivatives
---------------------|-----||-------||----------------------------  0 [Q] COG3424 Predicted naringenin-chalcone synthase
---------------------------||-------|-----|||||-||-----------|----  0 [Q] COG3433 Aryl carrier domain
----------------|-------------------|-----------|-----------------  0 [T] COG3434 Predicted signal transduction protein containing EAL and modified HD-GYP domains
-----------|--------------|----------|-----||-|--|-----|----------  0 [Q] COG3435 Gentisate 1,2-dioxygenase
------------------||------|||||||||-------------------------------  0 [R] COG3442 Predicted glutamine amidotransferase
-------------------------------||||-|-----|||-|------------|--|---  0 [R] COG3443 Predicted periplasmic or secreted protein
-----------------|----------------|--|----|---|---------------|---  0 [E] COG3457 Predicted amino acid racemase
-----------------|---------------|--||---------------------|--|---  0 [Q] COG3458 Acetyl esterase (deacetylase)
---------------------|---------------|----|------------|----|-----  0 [Q] COG3460 Uncharacterized enzyme of phenylacetate metabolism
--|--|-------------||-----|||----||--|-----------------|---||-|---  0 [L] COG3464 Transposase and inactivated derivatives
----||--|---------------------------||----------------------------  0 [S] COG3465 Uncharacterized conserved protein
|-|||--------------|||--------||-----|--------|------|||----|||---  0 [R] COG3467 Predicted flavin-nucleotide-binding protein
--|-----|-----|---||----------||----|----------------------||-----  0 [T] COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
-------------------------------|--|-------||||------------|-------  0 [S] COG3477 Predicted periplasmic/secreted protein
-||-----------------|----------|----|-----------------------------  0 [R] COG3478 Predicted nucleic-acid-binding protein containing a Zn-ribbon domain
-------------------------------|----|-----------|-----------------  0 [Q] COG3479 Phenolic acid decarboxylase
---|----------|----|-----------------|-------|---|-----|----|-|---  0 [Q] COG3486 Lysine/ornithine N-monooxygenase
--------------------|----------||---||--------|-|-----------------  0 [C] COG3493 Na+/citrate symporter
------------------------------||----||----|-----------------|--|--  0 [G] COG3507 Beta-xylosidase
-----------------|-------------------|-----||-|------------||-||--  0 [S] COG3533 Uncharacterized protein conserved in bacteria
-----------------|------------|-----||---------------------||-||--  0 [G] COG3534 Alpha-L-arabinofuranosidase
-------------------|------|---------|------------|----------|-||--  0 [P] COG3540 Phosphodiesterase/alkaline phosphatase D
-|-----------------|----------|-----|------------|-----|------|---  0 [R] COG3541 Predicted nucleotidyltransferase
-------------|----|--------------||--------------------|---||-||--  0 [S] COG3542 Uncharacterized conserved protein
---------------------|------------|-||-----------|-----|---|||||--  0 [R] COG3545 Predicted esterase of the alpha/beta hydrolase fold
----------|--------|----------|-----||-----||-|--|----------------  0 [P] COG3546 Mn-containing catalase
--|--------|-------||-----||||--||---|-------|---|---||----||-||--  0 [L] COG3547 Transposase and inactivated derivatives
-------------------------------------|-----------|------------|---  0 [S] COG3551 Uncharacterized protein conserved in bacteria
--------------------------|||--|-----|----------------------------  0 [M] COG3559 Putative exporter of polyketide antibiotics
------------------------------|||-|--------||-----|---|-----------  0 [K] COG3561 Phage anti-repressor protein
---------------------------||--------|----------------------|||---  0 [S] COG3564 Uncharacterized protein conserved in bacteria
---------------|--|-|---------|---|-----------------|------||-|---  0 [G] COG3588 Fructose-1,6-bisphosphate aldolase
---------------------------------||-|-----|||||-------------|-|---  0 [E] COG3591 V8-like Glu-specific endopeptidase
-------------------|----------------|-----------|---------------||  0 [R] COG3621 Patatin
--||-----------------|-----||-------|------------|---------|--||--  0 [R] COG3631 Ketosteroid isomerase-related protein
-------------------------------||-|-|-----|||-|--|--|--|-------|--  0 [O] COG3634 Alkyl hydroperoxide reductase, large subunit
---|---------------||-----|----|--|--|-|--||||---|---------||-||--  0 [P] COG3638 ABC-type phosphate/phosphonate transport system, ATPase component
---|------|--------||-----|----|--|--|-|||||||---|---------||-||--  0 [P] COG3639 ABC-type phosphate/phosphonate transport system, permease component
--------------|------|--------------||----------------------------  0 [Q] COG3648 Uricase (urate oxidase)
-----------------|--------------|----|----------------------------  0 [L] COG3649 Uncharacterized protein predicted to be involved in DNA repair
-----------------|-------------------|-------------------------|--  0 [G] COG3661 Alpha-glucuronidase
--------------|------|--------------|----------------------||--|--  0 [S] COG3665 Uncharacterized conserved protein
--|----------------||---------|-|||--|-----------|---------||--|--  0 [L] COG3666 Transposase and inactivated derivatives
------||----------||------|||||||||----------------------------|--  0 [K] COG3682 Predicted transcriptional regulator
-----------------|-|----------|------|---------------------|---|--  0 [G] COG3693 Beta-1,4-xylanase
-------------||---------------------|-----|||----------|---|||||--  0 [P] COG3703 Uncharacterized protein involved in cation transport
-----------------|||-----|-----------|-----------|--------||||||||  0 [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain
---------------------------||--------|----|||||-|-----------|-|---  0 [K] COG3710 DNA-binding winged-HTH domains
------------------------------------||----|||||------------||--|--  0 [G] COG3717 5-keto 4-deoxyuronate isomerase
-------------------|----------------|-----|||-|--|-------------|--  0 [R] COG3729 General stress protein
------------------------------------||----|||-|--------|---|---|--  0 [S] COG3766 Predicted membrane protein
------------------------------|-----||---------------------|||||--  0 [M] COG3773 Cell wall hydrolyses involved in spore germination
------------------------------------|------|||-----|---------||---  0 [R] COG3822 ABC-type sugar transport system, auxiliary component
-------------------------------------|---------------------||-||--  0 [S] COG3828 Uncharacterized protein conserved in bacteria
------------------------------|-----||----|||||-|||---------------  0 [KT] COG3835 Sugar diacid utilization regulator
---------------------|------------|-------|||||--|-|---|---||||---  0 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase
------------------||----------|-----||----------------------------  0 [S] COG3854 Uncharacterized protein conserved in bacteria
---------------------------||-|-----||----------------------------  0 [S] COG3856 Uncharacterized conserved protein (small basic protein)
------------------------------|-----||--------------|-------------  0 [R] COG3858 Predicted glycosyl hydrolase
-------------------|-|--------|------|----------------------------  0 [S] COG3860 Uncharacterized protein conserved in bacteria
-------------------|-|--------|-----|-----------------------------  0 [S] COG3861 Uncharacterized protein conserved in bacteria
--------|---------------------|-----|-----------------------------  0 [S] COG3863 Uncharacterized distant relative of cell wall-associated hydrolases
-----------------|------------|-----||----------------------------  0 [G] COG3866 Pectate lyase
-----------------|------------|-----||-------|--------------------  0 [G] COG3867 Arabinogalactan endo-1,4-beta-galactosidase
|-|---------------------------|-----||----------------------------  0 [S] COG3874 Uncharacterized conserved protein
----------------------||------|-----||----------------------------  0 [S] COG3876 Uncharacterized protein conserved in bacteria
---------------------------||-|-----||----------------------------  0 [S] COG3879 Uncharacterized protein conserved in bacteria
---------------------|--------|-----||----------------------------  0 [S] COG3881 Uncharacterized protein conserved in bacteria
------------------------------|------|--------------------|-|-----  0 [Q] COG3882 Predicted enzyme involved in methoxymalonyl-ACP biosynthesis
--|-----------------|-----|---|---|-------------|-------||--------  0 [L] COG3886 Predicted HKD family nuclease
--|-----------------------|----------|---------------------|--|---  0 [R] COG3910 Predicted ATPase
------------------------------|---|-|-----------------------------  0 [G] COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation
--|---------------||----------|------|----------------------------  0 [S] COG3937 Uncharacterized conserved protein
------------------------------|------|--------|-------------------  0 [R] COG3940 Predicted beta-xylosidase
-------------------------------||||----------------------------|--  0 [R] COG3942 Surface antigen
--------------------------|---|--||-||----------------------------  0 [M] COG3944 Capsular polysaccharide biosynthesis protein
---------------------|--------|------|----------------------------  0 [T] COG3947 Response regulator containing CheY-like receiver and SARP domains
------||------------------|---|---|-||----------------------------  0 [S] COG3949 Uncharacterized membrane protein
---------------------------||-||--|-|-----------------------------  0 [R] COG3953 SLT domain proteins
------------------------------|---|-||----------------------------  0 [R] COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain
--|----------||------------|||||--|-----------|-------------------  0 [GHR] COG3961 Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes
-------------------------------------|-------|-------------||||---  0 [I] COG3963 Phospholipid N-methyltransferase
-------------------------------------|-------|--|----------||-----  0 [P] COG3965 Predicted Co/Zn/Cd cation transporters
-------------------|----------||----|------------------|---||-----  0 [M] COG3967 Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
---------------------|----|---|-----|-----------------------------  0 [R] COG3973 Superfamily I DNA and RNA helicases
-|----------------------------|-----|-------------------|-|----|--  0 [M] COG3980 Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase
--------------------||----|---||||---|----------|--|----------|---  0 [R] COG3981 Predicted acetyltransferase
------||-|---------------------------|----------------------------  0 [S] COG4043 Uncharacterized conserved protein
||-------|--------------------------||----------------------------  0 [R] COG4085 Predicted RNA-binding protein, contains TRAM domain
|--------|--------------------|--|--||----------------------------  0 [S] COG4086 Predicted secreted protein
-----------------|----------------|-|-----------------------------  0 [R] COG4112 Predicted phosphoesterase (MutT family)
-------------------------------------|----|||||-------------|-----  0 [R] COG4114 Uncharacterized Fe-S protein
-------------------|-------||----||------------------------|-----|  0 [S] COG4115 Uncharacterized protein conserved in bacteria
------------------------------|-----|----------------------||||---  0 [G] COG4124 Beta-mannanase
-------------------------------------|----|||-----||--------------  0 [R] COG4146 Predicted symporter
--------|-------|--|-|----|---------||----|||||-||--|--|----------  0 [R] COG4147 Predicted symporter
----------------------------------|-------|||||-||||-------||||---  0 [P] COG4148 ABC-type molybdate transport system, ATPase component
-|------|-|||----|||||----|------|---|----|||||--|-----|--|||||---  0 [E] COG4177 ABC-type branched-chain amino acid transport system, permease component
---------------------|--------|-----|-----------------------|-----  0 [E] COG4187 Arginine degradation protein (predicted deacylase)
------------------||-----------------|-----------|-----|---|---|--  0 [R] COG4188 Predicted dienelactone hydrolase
-------------------------------------|---------------------||-|---  0 [K] COG4189 Predicted transcriptional regulator
------------------------------|--||-|-----------------------------  0 [G] COG4193 Beta- N-acetylglucosaminidase
---------------------------||-------|-------------------------|---  0 [R] COG4195 Phage-related replication protein
------------------------------|------|-------------------------|--  0 [S] COG4200 Uncharacterized protein conserved in bacteria
------------------||-------||--------|----|||||-||--||||---|||||--  0 [P] COG4208 ABC-type sulfate transport system, permease component
-------------------------------------|-|--||||----|----|---||||---  0 [G] COG4213 ABC-type xylose transport system, periplasmic component
-------------------------------------|-|--||||----|----|---||||---  0 [G] COG4214 ABC-type xylose transport system, permease component
------------------------------|---|----------------------------|--  0 [KT] COG4219 Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component
------------------------------|-----||-------||------------|------  0 [R] COG4225 Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
------------------||----------|---|-||----------------------------  0 [S] COG4241 Predicted membrane protein
-------------------|----------------|--------------------------|--  0 [I] COG4247 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
-------------------------------|----||-----------------|----------  0 [S] COG4260 Putative virion core protein (lumpy skin disease virus)
---|---------------|--------------|--|-------|---------|----|-----  0 [Q] COG4264 Siderophore synthetase component
-------------------|-|------------|--------------|----------------  0 [S] COG4270 Predicted membrane protein
---|---------------|------|----------|----------------------------  0 [S] COG4276 Uncharacterized conserved protein
-------------|||------||-|--------|-------------------------------  0 [G] COG4284 UDP-glucose pyrophosphorylase
--------------|----|-|--------------||----------------------------  0 [L] COG4294 UV damage repair endonuclease
---------------------|--------------|----------------------||-----  0 [S] COG4297 Uncharacterized protein containing double-stranded beta helix domain
-------------------|------|----||||------------------||-----------  0 [P] COG4300 Predicted permease, cadmium resistance protein
------------------------------------|---------------|--|----------  0 [G] COG4305 Endoglucanase C-terminal domain/subunit and related proteins
-------------------------------------|-----------|-----|---||-----  0 [S] COG4317 Uncharacterized protein conserved in bacteria
-------------------|----------------|------------|-----|----|-|---  0 [S] COG4319 Ketosteroid isomerase homolog
-------------------|----------------|-----------|-----------------  0 [R] COG4326 Sporulation control protein
-------------------|-----------------|----------|------|----------  0 [S] COG4327 Predicted membrane protein
-------------------|-----------------|----------------------|-----  0 [S] COG4329 Predicted membrane protein
----------------------------------|--------||---------------|-----  0 [S] COG4333 Uncharacterized protein conserved in bacteria
------------------------------------|--------------|-------|------  0 [L] COG4335 DNA alkylation repair enzyme
--------------|-----------|---------|------------|---------|------  0 [S] COG4336 Uncharacterized conserved protein
-------------||-----------------|||-------------------------------  0 [S] COG4357 Uncharacterized conserved protein
-------------||---------------|-----|-----------------------------  0 [E] COG4359 Uncharacterized conserved protein, possibly involved in methylthioadenosine recycling
---------------------|------------|-||----------------------------  0 [PE] COG4362 Nitric oxide synthase, oxygenase domain
---------------------|------------|-||----------------------------  0 [S] COG4365 Uncharacterized protein conserved in bacteria
---------------------------------|--|------------------|----------  0 [S] COG4377 Predicted membrane protein
------------------------------|------|--------------------|-------  0 [S] COG4378 Uncharacterized protein conserved in bacteria
-------------------|----------|-||---|----------------------------  0 [V] COG4403 Lantibiotic modifying enzyme
----------------------------------|--|-------|---|----------------  0 [S] COG4408 Uncharacterized protein conserved in bacteria
------------------------------|-----|-----------|-----------------  0 [S] COG4412 Uncharacterized protein conserved in bacteria
----------------------------------|----------|---|-----------|----  0 [E] COG4413 Urea transporter
-------------------------------------|-------------------------|-|  0 [G] COG4421 Capsular polysaccharide biosynthesis protein
------------------------------|--||-||----------------------------  0 [GM] COG4464 Capsular polysaccharide biosynthesis protein
--------------------|---------||-|--||----------------------------  0 [G] COG4468 Galactose-1-phosphate uridyltransferase
-------------------------------||||-||----------------------------  0 [S] COG4475 Uncharacterized protein conserved in bacteria
-------------------------------||||-|-----------------------------  0 [S] COG4485 Predicted membrane protein
--------------------|---------|---|-||----------------------------  0 [R] COG4492 ACT domain-containing protein
------------------------------||--|--|----------------------------  0 [S] COG4495 Uncharacterized protein conserved in bacteria
------------------------------|---|-|-----------------------------  0 [S] COG4502 Uncharacterized protein conserved in bacteria
------------------------------|------|-|--------------------------  0 [S] COG4508 Uncharacterized protein conserved in bacteria
--------------------------|||-----|-------|||--------------||||---  0 [S] COG4529 Uncharacterized protein conserved in bacteria
----------------------------------|-------|||||-||||---|----||||||  0 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB
----------------------------------|-|------------|---------|||----  0 [P] COG4548 Nitric oxide reductase activation protein
-------------------||------||--|-----|----------------------------  0 [R] COG4552 Predicted acetyltransferase involved in intracellular survival and related acetyltransferases
-----------------|---|--|-----|-----|---------------|-------------  0 [CP] COG4555 ABC-type Na+ transport system, ATPase component
--------------------------|-----|---||----|||-|-|-----------------  0 [KT] COG4565 Response regulator of citrate/malate metabolism
--------------------------||||-------|----|||-|----|----------|---  0 [K] COG4578 Glucitol operon activator
----------------------------------|-|-----|--------|--------------  0 [P] COG4594 ABC-type Fe3+-citrate transport system, periplasmic component
--------------------------|------||-||-------|--|----||---||-|----  0 [P] COG4604 ABC-type enterochelin transport system, ATPase component
--------------------------|------||-||-------|--|----||---||-|----  0 [P] COG4605 ABC-type enterochelin transport system, permease component
--------------------------|------||-||-------|--|----||---||-|----  0 [P] COG4606 ABC-type enterochelin transport system, permease component
--------------------------|------||-||-------|--|----||---||-|----  0 [P] COG4607 ABC-type enterochelin transport system, periplasmic component
----------------------------------|-------|||-|--------|----------  0 [R] COG4619 ABC-type uncharacterized transport system, ATPase component
------------------||-|---------------|----------------------------  0 [S] COG4627 Uncharacterized protein conserved in bacteria
------------------------------||----|-----------------------------  0 [G] COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
------------------------------|---|-|-----------------------------  0 [S] COG4640 Predicted membrane protein
------------------------------|-----||----------------------|-----  0 [S] COG4641 Uncharacterized protein conserved in bacteria
-------------------------------|-||--|----------------------------  0 [S] COG4652 Uncharacterized protein conserved in bacteria
---|----|---|--------|---------------|----------||-|--------||----  0 [R] COG4666 TRAP-type uncharacterized transport system, fused permease components
------------------||-|----|----------|-------|---|-----|---||-|---  0 [R] COG4674 Uncharacterized ABC-type transport system, ATPase component
------------------------------------|-----|||||--------|----------  0 [S] COG4682 Predicted membrane protein
-------------------------------|--|--|----------------------------  0 [S] COG4707 Uncharacterized protein conserved in bacteria
------||----------------------|||||-------------------------------  0 [S] COG4720 Predicted membrane protein
--------------------------|------||-|-----------------------------  0 [S] COG4721 Predicted membrane protein
-------------------------------|-|---|----------------------------  0 [G] COG4724 Endo-beta-N-acetylglucosaminidase D
---|----|----------------------------|-----------|-|--------------  0 [S] COG4729 Uncharacterized conserved protein
----------|-|--------------------||-------------------------------  0 [S] COG4732 Predicted membrane protein
---|--|||--|-||--|--||----||||------||-----------|-----|---|||||||  0 [I] COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
--------------------------||||-------|----------------------------  0 [S] COG4825 Uncharacterized membrane-anchored protein conserved in bacteria
--------------------|---------------|-----------------------|-|---  0 [R] COG4857 Predicted kinase
--|-----------------------|------|--|-----------------------------  0 [S] COG4894 Uncharacterized conserved protein
--|------------------|--------------|-----------------------------  0 [S] COG4895 Uncharacterized conserved protein
--------------------|-------------|-------------------------|-----  0 [R] COG4927 Predicted choloylglycine hydrolase
|-|-------|--------|------|---|-----||----------------------------  0 [KT] COG4978 Transcriptional regulator, effector-binding domain/component
------------------------------|-----|----------------------||||---  0 [S] COG4991 Uncharacterized protein with a bacterial SH3 domain homologue
----------|-|-------------|||-----|-|-----|||-|--|-----|-----|----  0 [C] COG5013 Nitrate reductase alpha subunit
--------------|---------------------|------------|----------------  0 [R] COG5018 Inhibitor of the KinA pathway to sporulation, predicted exonuclease
--------------|----|----------------|-----------------------------  0 [GM] COG5039 Exopolysaccharide biosynthesis protein
-------------||-------------------|-------------------------------  0 [H] COG5146 Pantothenate kinase, acetyl-CoA regulated
-------------------|-|---------------|-----------------|---|--||--  0 [T] COG5278 Predicted periplasmic ligand-binding sensor domain
-------------------|----------------|---------------|-------------  0 [S] COG5293 Uncharacterized protein conserved in bacteria
--|-----------------|----------------|-----||||---||||||----|||---  0 [UW] COG5295 Autotransporter adhesin
--|-----------------------|---------|-----------------------------  0 [M] COG5337 Spore coat assembly protein
------------------||----||----------||----------------------------  0 [R] COG5401 Spore germination protein
------|-|-|-------|-------|---------|-----------------------------  0 [S] COG5428 Uncharacterized conserved small protein
--------------------|-----|---||--|-------------------------------  0 [S] COG5438 Predicted multitransmembrane protein
-------------------------------------|-------|-------------|---|--  0 [S] COG5460 Uncharacterized conserved protein
-------------||----------------------|----------------------------  0 [M] COG5498 Predicted glycosyl hydrolase
---------------------|------------|-||----------------------------  0 [O] COG5504 Predicted Zn-dependent protease
-------|------------|---------------||----------------------------  0 [S] COG5505 Predicted integral membrane protein
--|-------------------------------|--------||||----|--------------  0 [L] COG5519 Superfamily II helicase and inactivated derivatives
------------------------------|-----|---------|----------------|--  0 [M] COG5520 O-Glycosyl hydrolase
--------------------|---|-|---------|-----------------------------  0 [S] COG5522 Predicted integral membrane protein
-------------------------------||||-------------------------------  0 [S] COG5547 Small integral membrane protein
------------------------------|---|-||----------------------------  0 [M] COG5577 Spore coat protein
-----------------|------------|-----||----|||||--|----------------  0 [M] COG5581 Predicted glycosyltransferase
------------------------------|-----||-----------|----------------  0 [S] COG5583 Uncharacterized small protein
--|---------------------------|-|----|----------------------------  0 [T] COG5585 NAD+--asparagine ADP-ribosyltransferase
-------------------|--------------|-||----------------------------  0 [S] COG5609 Uncharacterized conserved protein
-------------------------------------|-------------------------|-|  0 [R] COG5628 Predicted acetyltransferase
-------------------|----------------|------------------|----------  0 [S] COG5634 Uncharacterized conserved protein
------------------------|-||||------|-----------------------------  0 [S] COG5660 Predicted integral membrane protein
------------------||----|--||-------||-----------------|---||-|---  0 [K] COG5662 Predicted transmembrane transcriptional regulator (anti-sigma factor)
------------------------------|-----||------------------------|---  0 [S] COG5663 Uncharacterized conserved protein