(Sau) Staphylococcus aureus N315 Functional categories Fun All J A K L B D Y V T M N Z W U O C G E F H I P Q R S COGs 1,419 133 -  78 99 1 15 -  17 35 69 6 -  -  24 56 80 91 146 57 82 42 92 19 178 198 proteins 2,155 154 -  184 165 1 23 -  47 73 118 6 -  -  28 76 117 180 257 71 101 68 185 46 325 229 Distribution of COGs by number of proteins proteins 1 2 3 4 5 6 7 8 9 10 11 14 15 18 25 COGs 1057 221 65 32 15 7 7 7 2 1 1 1 1 1 1

Co-ocurrences in sister taxa 0 1 2 3 order Bacillales 55 133 253 978

++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
||||||||||||||||||||||||||||||||||||||-||||||||||||||||||||||||||| 25 [GEPR] COG0477 Permeases of the major facilitator superfamily
|||||||||||||----|-|||----||||||||||||----|||||-||--||||---|||||-- 18 [K] COG1846 Transcriptional regulators
|||||||||-||||||||||||||--|||||||||||||---|||||-||||||||||||||||-| 15 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
|||||||||--||---||||||||--||||||||||||||--|||||-|||||||||||||||||| 14 [L] COG0582 Integrase
----------------||||||||--||||||||||||----|||||-|||||||||||||||||| 11 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
-------------------------------||||----------------------------|-- 10 [R] COG3942 Surface antigen
|||||||||||||||||||||||||-||||||||||||----||||||||||||||||||||||||  9 [QR] COG0500 SAM-dependent methyltransferases
--------------------|----||---||||||||||||||||||||-|---|-------|--  9 [G] COG1264 Phosphotransferase system IIB components
-||||||||-|||----|||||----|---|||||||||---|||||-||||---|||||||||--  8 [P] COG0609 ABC-type Fe3+-siderophore transport system, permease component
|-||||||||||||||-|||-|---||||||||||||||||-|||||-||-|||||||-|||||--  8 [V] COG1131 ABC-type multidrug transport system, ATPase component
||||----|||||---|||||||||||||-||||||||||||||||||||||||||||||||||||  8 [V] COG1136 ABC-type antimicrobial peptide transport system, ATPase component
--------------------|----||---||||||||-|||||||||||-|---|-------|--  8 [G] COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific
|-|-------|-----||-|||--|-|||-||||||||----|||||-||||||||---|||||||  8 [K] COG1396 Predicted transcriptional regulators
--|--|-------------||-----|||----||--|-----------------|---||-|---  8 [L] COG3464 Transposase and inactivated derivatives
---------------------------------||-|-----|||||-------------|-|---  8 [E] COG3591 V8-like Glu-specific endopeptidase
||||||||||||||||||||||---|||||||||||||----|||||-||||||||||||||||||  7 [M] COG0438 Glycosyltransferase
||||||||||||-||-||||||---|||||||-|||||----|||||-||||||||||||||||--  7 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases
|-||||||||||||||-||||||||||||||||||||||||||||||||-||-|||---||-|---  7 [R] COG0561 Predicted hydrolases of the HAD superfamily
|-||||--|-||-||||-||||---|||||||||||||----|||||||||||||||||||-||||  7 [P] COG0607 Rhodanese-related sulfurtransferase
|-||----|----||-||||||||-|||||||||||||----|||||-||||||||||||||||||  7 [T] COG0642 Signal transduction histidine kinase
|-||---||--|----||||||----|||||||||||||---|||||-||||||||--||||||--  7 [K] COG1309 Transcriptional regulator
--------------------|-|||||---||||||||-||||||||-||||-|||---|||||--  7 [GT] COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  6 [J] COG0030 Dimethyladenosine transferase (rRNA methylation)
|-||--|||--||||---||||----||||||||||||----|||||-||||||||--||||||--  6 [E] COG0346 Lactoylglutathione lyase and related lyases
||||||--||||||||--|||-||--|||||||||||||||||||||-|||||--|---|||||||  6 [E] COG0531 Amino acid transporters
||||----||||-----||||||||-|||-||||||||----|||||-||-|-|||--||||||--  6 [V] COG0577 ABC-type antimicrobial peptide transport system, permease component
||||||---||||||-|-||||----|||||||||||||---|||||-||-|-|||||||||||-|  6 [C] COG1012 NAD-dependent aldehyde dehydrogenases
--|||||||-||||||||||||||--||||||||||||----||||||||||||||||||||||||  6 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
--|----------------||---------|-|||--|-----------|---------||--|--  6 [L] COG3666 Transposase and inactivated derivatives
||||||||||||||||||||||---||||||||||||||||||||||-||||||||||||||||||  5 [M] COG0463 Glycosyltransferases involved in cell wall biogenesis
|||||||||-||||||||||||||||||||||||||||||||||||||||||||||||||||||||  5 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins
||------||------|-||||----||||||||||||----|||||-||||||||--||||||--  5 [K] COG0583 Transcriptional regulator
---|||-|--|-||||-|-|||--|-||||||||||||-||||||||-||||---|---|||||--  5 [C] COG0584 Glycerophosphoryl diester phosphodiesterase
--|||||||-|||---||||||||-||||||||||||||||||||||-||||---||||||||---  5 [EP] COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components
----||||--|||||-|-|||---|-----|-|-||||----|||||-||||-|||||||||||--  5 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases
--|||||||-|||---||||||||-||||||||||||||||||||||-||||---||-|||||---  5 [EP] COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components
--||||||---|-----|||||----|||-||-|||||----|||----|||---|--||||||--  5 [R] COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase
|||---|||||||---||------------|---|-----------|---|--------||----|  5 [R] COG1708 Predicted nucleotidyltransferases
|-----|------------------------|--|||------------|--|-------------  5 [M] COG1887 Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC
-----------------||||-----|||-||-|||||----|||||-||||||||--||||||--  5 [K] COG2207 AraC-type DNA-binding domain-containing proteins
--|------------------|--||------|||-------------------------------  5 [V] COG2348 Uncharacterized protein involved in methicillin resistance
--|-||--|----||---||||----|||--|||||-|||--|||||-|||--|||---|||||--  5 [L] COG2801 Transposase and inactivated derivatives
--------------------|-----|---||||||||----|||||-------------------  5 [K] COG3711 Transcriptional antiterminator
---|---------------|--------------|--|-------|---------|----|-----  5 [Q] COG4264 Siderophore synthetase component
---|||||---||||-||||--||--|----|||||||-||||||||-||----------------  4 [H] COG0095 Lipoate-protein ligase A
--|||||||-|||---||--||||-||---|||||||||||||||||-||||---||||||||---  4 [EP] COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
|||||||||--|-|||||||||||||----||||||||----|||||-||-|||||||||||||||  4 [R] COG0457 FOG: TPR repeat
||||||||||||||||||||||----||||||||||||----||||||||||||||||||||||--  4 [R] COG0491 Zn-dependent hydrolases, including glyoxylases
||||||||||||||-|||||||||||||||||||||||||||||||||||||||||||||||||||  4 [O] COG0492 Thioredoxin reductase
|-||||--|-|||||||||||||||-||||||||||||----||||||||||||||||||||||||  4 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
|||||||||||||||--|||-|----||||||||||||----|||||-|||||--|---|||||--  4 [G] COG0524 Sugar kinases, ribokinase family
--||||--|-|||||||-||||---|||||||-||||||||||||||-||||||||||||||||||  4 [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) 
-||||||||-|||----|||||----||||||||||||----|||||-||||---|||||||||--  4 [P] COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component
|||||||||||||---||||||----|||||||-||||----|||||-||-|||||--||||||--  4 [K] COG0640 Predicted transcriptional regulators
--|--|--|--|-||--|||-|--|-|||||||-||-|----|||||-||--|--|---||-||--  4 [I] COG0657 Esterase/lipase
|||||||||||||---||||||----|--|||--||||----|||||-||||||||||||||||--  4 [R] COG0730 Predicted permeases
|--|----|----||-|||--|--|-|---|||-||||-|--|||||-|-||---|||-||-|---  4 [F] COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases
----------------||||||--||||||||--||||----||||||||||||||||||||||||  4 [M] COG0739 Membrane proteins related to metalloendopeptidases
--|||||||-|||---||||||||--|||||||-||||----|||||-||||---||||||||---  4 [E] COG0747 ABC-type dipeptide transport system, periplasmic component
--|-----|-------|-||||----||||||||||||----|||||-||||||||||||||||||  4 [K] COG0789 Predicted transcriptional regulators
--|||||||--||||--|-|-|-----||-||||||||--|-|||||-|||-||||---||-||--  4 [ER] COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
--------------------------|||||||-||||----|||||--|---------|-|----  4 [E] COG1113 Gamma-aminobutyrate permease and related permeases
||||--|||||||----|||||--|-||||||||||||||||-||-|-|-|----|---|||----  4 [P] COG1122 ABC-type cobalt transport system, ATPase component
--||--||--||-|||||||||||--||||||||||||||||||||||||||||||||||||||||  4 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components
|-||--||--|-|---|||||||||||||-||||||||-----||||-||-----|------||--  4 [R] COG1266 Predicted metal-dependent membrane protease
--------------------||---||---||||||||-||||||||-|||----|----------  4 [G] COG1299 Phosphotransferase system, fructose-specific IIC component
-----------------|--||----|||-||||||||-|--|||||-|||||--|---|||||--  4 [K] COG1609 Transcriptional regulators
-|||||-|-----||--|-|||----||||||||||||--|-|||||-||-|-|||||||||||||  4 [J] COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
-----------------|--------|---||||||||-|--|||||-||||-|||---|||||--  4 [K] COG1737 Transcriptional regulators
-----||---|-------||-|----|||-|-||||||----|||||-||--|--|---|||||--  4 [L] COG1961 Site-specific recombinases, DNA invertase Pin homologs
||||--||---------|||-|----|-------||||----------||---------|||--||  4 [P] COG2111 Multisubunit Na+/H+ antiporter, MnhB subunit
-------------------|-|----|||-||||||||||--|||||-||-----|---|||||--  4 [K] COG2188 Transcriptional regulators
--------------------|----||---||||||||-|||||||||||||---|-------|--  4 [G] COG2190 Phosphotransferase system IIA components
------------------||-|----|||-||||||||----|||||-||||||||---|||||--  4 [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
--|------------------------||-----||-|-----|||---------|---||-|---  4 [L] COG4584 Transposase and inactivated derivatives
------------------||-|----|||-||||||||-----------|-----|---||-||--  4 [T] COG4585 Signal transduction histidine kinase
|||-||-||||||||-||||-|----||||||-|||||----||||||||||||||--||||||--  3 [EH] COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]
--||||-|--|||||-||||||----||||||||||||----||||||||||||||||||||||--  3 [E] COG0031 Cysteine synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  3 [R] COG0073 EMAP domain
||||---|-||--||--|||-|||--||||||||||||----|||-|-||-|-|||--||||||-|  3 [R] COG0110 Acetyltransferase (isoleucine patch superfamily)
||||----|||--||-||||||----||||||||||||----|||||-||||||||||||||||||  3 [EH] COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase
||||||||||||||||--|-||---||||||||-||||----|||||-|||----|||-|||||||  3 [I] COG0183 Acetyl-CoA acetyltransferase
|-||-------|-||---||||--|-|||||||||||||||||||||-||||||||||||||||--  3 [O] COG0225 Peptide methionine sulfoxide reductase
|-||||--|-|||||---||-|||--||||-||-||||----|||||-||||||||--||||||||  3 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II
||-|--||---------|||-|--------||-||||-----|||||-||-|-|||--|-----||  3 [M] COG0381 UDP-N-acetylglucosamine 2-epimerase
|-||----|----||-|-||-|----|||-||||||||----|||-|-||-|||||--||||||--  3 [T] COG0394 Protein-tyrosine-phosphatase
||||||--||||----|||||-------------|-|-----||||||||||-|||--||||||--  3 [O] COG0425 Predicted redox protein, regulator of disulfide bond formation
|||||||||||||||-|||||||||-||||||||||||----|||||-||||||||||||||||||  3 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase
||-|--||-||--||-|-|--|||--|---|||||-||----|||||-||||||||||||||----  3 [P] COG0471 Di- and tricarboxylate transporters
-------------|||--||||||||||||||||||||-|--||||||||||||||||||||||||  3 [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains
||||||||||||||||||||||----|||||--|||||----|||||-||||||||||||||||||  3 [D] COG0489 ATPases involved in chromosome partitioning
||||--||-||||||--|||||--|||||-||||||||||||||||||||||-||||||||||---  3 [F] COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins
---|||----|||||---||-|||--||||-|||||||-|||||||||||||||||---|||||||  3 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes
||-|||||-|--|||-||||||-|-|||||||||||||----||||||||||||||||||||||--  3 [F] COG0516 IMP dehydrogenase/GMP reductase
--|----------||-|-||||----|||-----|-||----|||||-||--||||||-|||||--  3 [R] COG0523 Putative GTPases (G3E family)
|------------||||||||||||||||||||||||||-|||||||-||||||||||||||||||  3 [O] COG0542 ATPases with chaperone activity, ATP-binding subunit
|-||--|||----|--|-||-|--|||||-|||||||||---|||||-||||||||||||||||--  3 [R] COG0546 Predicted phosphatases
-------------|||||||||||||||||||||||||||||||||||||||||||||||||||||  3 [J] COG0564 Pseudouridylate synthases, 23S RNA-specific
--||||----||-||-|--|-|----||||-|--||||----|||||-||-||--|---|||||--  3 [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases
||||--||||-||----|||||----||||||||||||||||-||-|---|--------|||----  3 [P] COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters
--||||||--|||||--|--||----||||||||||||----|||||-||||||||||||||||--  3 [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  3 [L] COG0629 Single-stranded DNA-binding protein
---|||||--||||||-||-------||||||||||||----|||||--|-----|---|||||--  3 [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase
|-|||||||-|||||||||||||||-|||-||-|||||----||||||||||||||||||||||||  3 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily
---|---------||-|-||-|----|----|--||||----|||||-|||-|--|---|||||--  3 [MG] COG0702 Predicted nucleoside-diphosphate-sugar epimerases
--|-||--|-|||---||||||---||||||||-||||--|||||||-||||||||||||||||--  3 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins
-----------------|||||----||||||||||||----||||||||||||||||||||||--  3 [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein)
----------------||||||||||||||||||||||----||||||||||||||||||||||||  3 [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2
|||||--||||||---||||||----||||||||||||----|||||-||||||||||||||||--  3 [C] COG0778 Nitroreductase
|-||||----|||---|-||||--|-|||-|---||||----|||||-||||||||||||||||--  3 [R] COG0824 Predicted thioesterase
----|---|----||||||--||||-|||-||||||||----||||||||||||||||||||||||  3 [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
--||||-||-|||---|-||-|----|||-----||||----||||||||--||||||||||||||  3 [CP] COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit
-------------||----|------||||-||||||-----|||||-||-----|--||-||---  3 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins
--------------------|-|||-|---|-|||-|-----|||||-||||--------------  3 [E] COG1114 Branched-chain amino acid permeases
--------|----------|||-----||-|||||||-----|||||--|-----|||-||||---  3 [E] COG1174 ABC-type proline/glycine betaine transport systems, permease component
||||||--|||||||-||||||||--||||-|||||||-|||||||||||||||||---|||||||  3 [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
---|------------||--||----|||||||-||||----||||||||||||||---|||||||  3 [K] COG1278 Cold shock proteins
---|--------------------|-|||-----||||----|||||-||||-||-----|-----  3 [M] COG1292 Choline-glycine betaine transporter
-----------------|--||||------||||||||----------------------------  3 [S] COG1302 Uncharacterized protein conserved in bacteria
-----------------|||-|--||||||||||||||----------------------------  3 [K] COG1316 Transcriptional regulator
--|||||||||||||-||-|-|--|||||-||||||||----|||||-||--||||--||||||--  3 [Q] COG1335 Amidases related to nicotinamidase
||||--|||||-|----|-|||--------||||||||||--|||-|--|----------|-----  3 [G] COG1363 Cellulase M and related proteins
----------------|----|||-||||-||--||||-------|--||||--------------  3 [M] COG1388 FOG: LysM repeat
||-|--|||-|||---|--|-|||||||||||||||||----|||||-||--||||||||||||||  3 [K] COG1475 Predicted transcriptional regulators
|--------------------|----||||||||||||----------------------------  3 [S] COG1511 Predicted membrane protein
-------------------|-||||||||||||||||||---|||||-||||||||||||||||||  3 [D] COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins
------------------||-|----||||||--||||----|||-|--|-----|--|||-----  3 [S] COG1937 Uncharacterized protein conserved in bacteria
---|||--|-|-|---||||||---|||||||||||||-|--|||||-|-||-------|||||--  3 [KG] COG1940 Transcriptional regulator/sugar kinase
---|||--|-||||-----|||----|||||---|-||----|||||-||---|||---|||||--  3 [I] COG1960 Acyl-CoA dehydrogenases
-------------------|------------|-|-||----|||||-|-||----||-----|--  3 [F] COG1972 Nucleoside permease
---|||------------||-|-----||-|---||------|||||--|-----|---||-||--  3 [P] COG2060 K+-transporting ATPase, A chain
||||----||-|-------|-|----||||--||||||-|--|||||--|--|--|---|||||--  3 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
||||||||||-|-----|-|||----|---||||||||----|||||-||||||||---|||||--  3 [R] COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
---|||-----||--------|----||||----||||-----------|-----|---||||---  3 [R] COG2329 Conserved protein involved in polyketide biosynthesis related to monooxygenase
--------------------|---------||||||||----|||||-||--|--|---|||||--  3 [KT] COG3279 Response regulator of the LytR/AlgR family
--------------------------|||-|-||||||---------------------|-|----  3 [S] COG4129 Predicted membrane protein
------------------------------|--||-|-----------------------------  3 [G] COG4193 Beta- N-acetylglucosaminidase
--|||||||-|||---||--||||-||---||||||||-||||||||-||||---||||||||---  3 [E] COG4608 ABC-type oligopeptide transport system, ATPase component
-------------------------------|--|||-----------------------------  3 [S] COG5294 Uncharacterized protein conserved in bacteria
--|-------------------------------|--------||||----|--------------  3 [L] COG5519 Superfamily II helicase and inactivated derivatives
------------------------------|---||-|----------------------------  3 [L] COG5655 Plasmid rolling circle replication initiator protein and truncated derivatives
||||||--|||||-|-|-||||||--|||||---||||----|||||-||-|||||||||||||--  2 [H] COG0001 Glutamate-1-semialdehyde aminotransferase
|||||||||||||||||||||||||||||||||||||||||||||||-||||||||||||||||||  2 [E] COG0006 Xaa-Pro aminopeptidase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||---|||||||  2 [J] COG0009 Putative translation factor (SUA5)
|||||||||||||||---||||--------|-|-|-||----|||-|-||-|||||||-||||---  2 [E] COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family
||-||||||||--|--|||-------|||-|--||-||----------------------------  2 [S] COG0011 Uncharacterized conserved protein
|||-||--||---||-||||-|----||||||-|||||----||||||||||||||||||||||--  2 [E] COG0019 Diaminopimelate decarboxylase
---|||----||||||--||-|||---||--|||||||-|||-------|-----|---|||||||  2 [C] COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
||||||-|||---|||--||-|----|||--|-||||-----|||||-||-||------|--|---  2 [P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters
||||||--|||||||-||||||||-|||||||||||||-||||||||-|-|||--|--||||||||  2 [C] COG0039 Malate/lactate dehydrogenases
||||----||---|||||||||||||||||||||||||----|||||-||||||||||||||||||  2 [J] COG0042 tRNA-dihydrouridine synthase
||||||||||||||||||||||||||||||||||||||-|||||||||||||||||||||||||--  2 [G] COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase
|||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||--  2 [E] COG0069 Glutamate synthase domain 2
|||||||||||||||-||||-|---|||||||||||||--|-||||||||||||||--||||||--  2 [E] COG0078 Ornithine carbamoyltransferase
|||||||||||||||-||||||----||||||--||||----||||||||||||||--||||||--  2 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase
|||||||||||||||-||||-|----||||||--||||----|||||-|||||--|||||||||--  2 [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases
|||--|||||||-||-||||-|----|||||--|||||----||||||||||||||--||||||--  2 [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases
||||||||||||||||||||||||||||||||||||||----||||||||||||||||||||||||  2 [H] COG0142 Geranylgeranyl pyrophosphate synthase
||||||-||||||||-||||||----||||||||||||----||||||||||||||||||||||--  2 [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I
-|--||||-----||||-||||||---|||----|-||----|||||-||||||||||||||||||  2 [H] COG0156 7-keto-8-aminopelargonate synthetase and related enzymes
||||--||||--|||-||||||--||------||||||-||||||||-||||-||---||||----  2 [P] COG0168 Trk-type K+ transport systems, membrane components
--||||--|----|||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
--||||--|----|||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [J] COG0199 Ribosomal protein S14
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [U] COG0201 Preprotein translocase subunit SecY
|-||||-------||-||||||||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0210 Superfamily I DNA and RNA helicases
--|----------||-||||||||||||||||||||||||||||||||||||||||||||||||||  2 [IQ] COG0236 Acyl carrier protein
-|||--||-|---||-||||-|----|||-|--|||||----|||||-||||||||||||||||--  2 [D] COG0239 Integral membrane protein possibly involved in chromosome condensation
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  2 [J] COG0242 N-formylmethionyl-tRNA deformylase
--||-|-------|||||||||||||----|||-||||----||||||||||||||---|||||||  2 [L] COG0249 Mismatch repair ATPase (MutS family)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0258 5'-3' exonuclease (including N-terminal domain of PolI)
|-||------||-||-||||||||||||||||||||||----||||||||||||||||||||||||  2 [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
-------------||-|||||||||||||||||||||||||||||||||||||||||||-||||||  2 [J] COG0267 Ribosomal protein L33
|--|||----|-|---||||-|--|-|||||||||||||||||||||-|-||-------||-|---  2 [F] COG0274 Deoxyribose-phosphate aldolase
||||---||----------|-------||--|||||--|||-|||-|-|||||||||||-||-|-|  2 [V] COG0286 Type I restriction-modification system methyltransferase subunit
||||--||||---|||---|||||||||-|||||||||||--||||||||||-||||||-------  2 [S] COG0327 Uncharacterized conserved protein
|||||||||||||---|||||-||--||||||||||||----||||||||||||||||||||||||  2 [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase
|||||||||||||||-||-|||--|-||||||||||||----|||||-||||||||||||||||--  2 [H] COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase
|-||||--|-|||||||-||-|-----||--|--||||----|||||-||-||--||-||||||--  2 [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases
--|-||----|--||--|||-|----|||-||||||||-|--|||||-||-----|---||-||--  2 [G] COG0366 Glycosidases
|||---|||||-----||||-|--------||--||------|||||-||--|--||||----|--  2 [P] COG0370 Fe2+ transport system protein B
-------------|||--|-|-----|---|||||||||---|||||--|--||||-------|--  2 [O] COG0386 Glutathione peroxidase
--||-------|-||---|||-----|||-|||||||||||||||||-||-|-|||---|||||--  2 [L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair
--|-||-----|-||-||||||----||||||||||||----|||||-||-||--|---|||||--  2 [G] COG0406 Fructose-2,6-bisphosphatase
||||||||||||||||||||||--||||||||--||||----|||||-||----------|-----  2 [L] COG0420 DNA repair exonuclease
---|---------||---||-|----|||--|||||||--|||||||-||-|-|||---||-||--  2 [R] COG0431 Predicted flavoprotein
|||-----|--|-||-|-||-||||--||-||||||||----|||||-||||||||||||||||--  2 [I] COG0439 Biotin carboxylase
|||||||||||||||-||||||--|||||-||||||-|-||||||||-||-|---|---|||||--  2 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases
||||||||||||||||||||||----|||||||||||||---|||||-||||||||--||||||--  2 [R] COG0456 Acetyltransferases
||----||-|||-||-||||||||||||||||||||||----|||||||||||||||||||||-||  2 [M] COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase
||||--||||||||--||||-|---|||||-|||||||----|-||||||||||||--||||||||  2 [G] COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family
---|||||---||||-||||-|||---|||--|-||||-|--|||||-||--||||---|||||--  2 [E] COG0509 Glycine cleavage system H protein (lipoate-binding)
|||---|||--|-||-|||||||||-||||||||||||----|||||-||||||||||||||||--  2 [I] COG0511 Biotin carboxyl carrier protein
||||||-||||||||-||||||----||||||||||||----||||||||||||||||||||||--  2 [EH] COG0512 Anthranilate/para-aminobenzoate synthases component II
|||-||--|--|-||||-||||--|-||||||||||||||||||||||||||||||||-|||||||  2 [LKJ] COG0513 Superfamily II DNA and RNA helicases
--|---------||||--||||--|-|---||--||||----|||||-||||||||---||-||--  2 [L] COG0514 Superfamily II DNA helicase
---|||----||-||||-||-|||--||||||||||||||||-|-|--|||||--||--|--|---  2 [RTKL] COG0515 Serine/threonine protein kinase
|||||||||||||||-||||||||-|||||||||||||----|||||-||||||||||||||||||  2 [R] COG0517 FOG: CBS domain
|||||-|||||||||-||||-|||--||||||-|||||----||||||||||||||||||||||||  2 [E] COG0527 Aspartokinases
---|||||--|-|-----|------------||||-----|-|||-|--||---------|-----  2 [E] COG0549 Carbamate kinase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2 [L] COG0550 Topoisomerase IA
|||||||||--------|--|-|||-----|||||||||-|||||||||||||||||||-------  2 [L] COG0551 Zn-finger domain associated with topoisomerase type I
--------|----||-|||||||||||||||||||||||||||||||-||||||||||||||||||  2 [J] COG0566 rRNA methylases
||||--|||||-|---||||||--||-||---||||||-||||||||-||||-||---||||----  2 [P] COG0569 K+ transport systems, NAD-binding component
----|--||---|----||||-----|||-|---|--|-||||||-|-||--||||||||||||--  2 [R] COG0579 Predicted dehydrogenase
|||||||||||||-|-|-||-|----||||-|||||||----|||||-||||-|||---|||||||  2 [T] COG0589 Universal stress protein UspA and related nucleotide-binding proteins
|-|||||||--||||---|-|--|--|------||-||----|||||-||||-||||||||||-||  2 [ER] COG0591 Na+/proline symporter
||||--||-|-------|||||----||||||||||||||||--------------||||||||||  2 [R] COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily
-||---|-|-||-||-||||||----|||||||||||-----|||||-|||||--|||||||||-|  2 [P] COG0598 Mg2+ and Co2+ transporters
||||||||||||----|-|||---------||||||||----|||||-||||||||||||||||||  2 [O] COG0602 Organic radical activating enzymes
|-||||----|||||||-||-|||-|||||||||||||----||||||||||||||||||||||||  2 [P] COG0605 Superoxide dismutase
----------|-|||-||||||---|-|||||||||||----|||||-|||||--|||||||||||  2 [R] COG0612 Predicted Zn-dependent peptidases
|||||||||||||---||||||-||-|||||---|-||----||||||||||||||||||||||||  2 [J] COG0621 2-methylthioadenine synthetase
-|--|||||||||||-||--||-|--||||||||||||----||||||||||||||||||||||||  2 [E] COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases
||||--|||-------||||||--|||||-||||||||----||||||||||||||||||||||||  2 [R] COG0628 Predicted permease
||||-||||-|||----|||-|----|||-----||||----|||-|-||---------|||--||  2 [CP] COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  2 [U] COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase)
---|||----|||||-||||||---|||||-|--||||----|||||-||--|--||--||-||--  2 [C] COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)
||||--||-|-|-||||-||||--|-||||||||||||----|||||-|||||--|||-|||||||  2 [I] COG0671 Membrane-associated phospholipid phosphatase
|-||||||-|||-||-||||-|----|---||||||||----|||||-||-|---|||||||||--  2 [R] COG0673 Predicted dehydrogenases and related proteins
||||||||||||||||||||||||||||||||||||||-|--||||||||||||||||||||||||  2 [U] COG0681 Signal peptidase I
------------------||-|-----|||-|--||||----------|-------||--|-||--  2 [E] COG0686 Alanine dehydrogenase
-||||||||||||||-|-||||--||-||-|--|||||-||||||||-||-||--|--||||||--  2 [R] COG0693 Putative intracellular protease/amidase
----------------|||-|-----|||||-|||||||||||--||----|----|||-|||-||  2 [G] COG0698 Ribose 5-phosphate isomerase RpiB
--|------|-|----||||||||||||||||||||||----||||||||||||||||||||||||  2 [M] COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase
|||||||||||||----|||-||||-||||||||||||----|||||-----|------|||||--  2 [O] COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component
||||-|-||----------|-------||--|||||--|||||||-|-|||||---|||-||-|-|  2 [V] COG0732 Restriction endonuclease S subunits
----------------||||||||||||||||||||||----||||||||||||||||||||||||  2 [OU] COG0740 Protease subunit of ATP-dependent Clp proteases
--|-----|-|-|----|||||||--|---||||||||----|||||-|||--|||||||||||||  2 [E] COG0765 ABC-type amino acid transport system, permease component
----------------||||||||||||||||||||||----||||||||||||||||||||||||  2 [M] COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase
|--------|------||||||||||||||||||||||----||||||||||||||||||||||||  2 [M] COG0769 UDP-N-acetylmuramyl tripeptide synthase
----------------||||||||||||||||||||||----||||||||||||||||||||||||  2 [D] COG0772 Bacterial cell division membrane protein
--------------|-|-||||--||||||||||||||----|||||-||||||||||||||||||  2 [M] COG0787 Alanine racemase
|-||--|||-|-|---|||||||||-||||||||||||-------||--|||-||---|||-|-||  2 [P] COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin
-----------|--------||--|------||||||-|||||||||||-||----||----|---  2 [F] COG0813 Purine-nucleoside phosphorylase
|||------|-|----|--|||--------||||||||----|||||-||||-|||||||||----  2 [O] COG0826 Collagenase and related proteases
-------------||---------------||--|||-----|||||--|-----|||--------  2 [E] COG0833 Amino acid transporters
--|-----|-|-|----||||||||-||||||||||||----|||||-||||-|||||||||||||  2 [ET] COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain
------||||||||||||--||----|||||-|-||||-|--|||||-||-|---||||----|--  2 [K] COG0846 NAD-dependent protein deacetylases, SIR2 family
||||--||---------|||-|----|-------||||----------||---------|||--||  2 [P] COG1006 Multisubunit Na+/H+ antiporter, MnhC subunit
||||--||-|||-|||-|-|-|--|||||-||||||||----|||||-||-|-|||---|||||--  2 [R] COG1011 Predicted hydrolase (HAD superfamily)
----|||||-|||----||||-||---|||----||||----||||--||---|||--||--|---  2 [P] COG1055 Na+/H+ antiporter NhaD and related arsenite permeases
--|||||||-||||||---|||--|-|||||-||||------|||||-|-----------------  2 [KL] COG1061 DNA or RNA helicases of superfamily II
--------|----||---||-|----|---|---|-||-|--------||--|--|----------  2 [R] COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold
-|---------------|--|---|-|---|--||-||----------||-||||||||-||||||  2 [MG] COG1086 Predicted nucleoside-diphosphate sugar epimerases
-----------------|---|--------||||||||----------------------------  2 [J] COG1098 Predicted RNA binding protein (contains ribosomal protein S1 domain)
--|-----|----||||||||||||-||||||||||||----||||||||||-|||||||||||||  2 [E] COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes
-----------------|--||---||||-||||||||--|||||||-||||---|----------  2 [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)
|-||--|||-|-|---|||||||||-||-|||||||||----||||||||||-||---|||||-||  2 [P] COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components
|||||||||||||||||||||||||||||||||||||||-||||||||||||||||||||||||||  2 [G] COG1109 Phosphomannomutase
--|---||------------|||||-|-----|||-||----|||-|-||||-||-|||-||----  2 [E] COG1115 Na+/alanine symporter
|-||--|||-|||---|||||||||-|--|||||||||----||||||||||-||---|||||-||  2 [P] COG1121 ABC-type Mn/Zn transport systems, ATPase component
--------|----------|||-----||-|||||||-----|||||--|------||-||||---  2 [E] COG1125 ABC-type proline/glycine betaine transport systems, ATPase components
--|-----|-|-|----|||||||--|---||||||||----|||||-|||--|||||||||||||  2 [E] COG1126 ABC-type polar amino acid transport system, ATPase component
--|-----|-------|-||------|||||||-||||--------|-||-||||---|-||||||  2 [GM] COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component
------------------||||-||-|---||||||||----|||||-||||||||||||||||--  2 [P] COG1135 ABC-type metal ion transport system, ATPase component
-||---||-|||||||-||||----|----||||||||||||------|----||-----------  2 [R] COG1161 Predicted GTPases
--||-------------|--||||||-----|||||||||||------|-------||||||||--  2 [E] COG1164 Oligoendopeptidase F
----||||--|||||--|-|||----|||||-||||||----|||||-||-|---|---|||||--  2 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
---|||----|||||--|||||----||||-|-|||||----|||||-||||||||--||||||||  2 [E] COG1171 Threonine dehydratase
----------------||||||||||||||||||||||-|--||||||||||||||||||||||||  2 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases
------|---------|||||||||-|||||--|||||--||||||||||||||||||||||||--  2 [I] COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase
--|---|---||-|||||-|-|----|--||||||||-----|||||--|-|||||--||||||--  2 [P] COG1230 Co/Zn/Cd efflux system component
||||-------||-----||-|----|||-----||-|-----------------|------||--  2 [Q] COG1233 Phytoene dehydrogenase and related proteins
||||||||||----|-|-|||-||||----||||||||----||||---|-----|---|||||||  2 [R] COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
---|-------|-||---||-|----||||-|--||||----|||||-|||----|---||||---  2 [C] COG1252 NADH dehydrogenase, FAD-containing subunit
--------------------|----|------|||-||----|||-|---|------------|--  2 [S] COG1288 Predicted membrane protein
-----------------|--||----|||-||||||||||||-------|----------------  2 [S] COG1307 Uncharacterized protein conserved in bacteria
||||--||---------|---|----|-------||||----------||---------|||--||  2 [P] COG1320 Multisubunit Na+/H+ antiporter, MnhG subunit
--|---||------------||--------||--|-||----|||||-||||-|||-----|----  2 [M] COG1346 Putative effector of murein hydrolase
----------------||--||----|---||||||||----|||||-||||-|||---||||---  2 [KG] COG1349 Transcriptional regulators of sugar metabolism
||||||||||||||||-|--|---------||||||||----------------------------  2 [J] COG1358 Ribosomal protein HS6-type (S12/L30/L7a)
--|---||------------||--------||--|-||----|||||-||||-|||-----|----  2 [R] COG1380 Putative effector of murein hydrolase LrgA
-------------------|||----|--||||||||||-|||||||-||||||||--||||||--  2 [P] COG1393 Arsenate reductase and related proteins, glutaredoxin family
||||||||||------||--||--||----|||||||||-|||||-|---------|||||-----  2 [R] COG1418 Predicted HD superfamily hydrolase
---------------------|---|-----||-|||-||||-------------|----------  2 [F] COG1428 Deoxynucleoside kinases
-----------------|---|-|--||||||||||||----|||||-|-||--------------  2 [K] COG1438 Arginine repressor
--------------------||---||---||||||||-||||||||-||||---|----------  2 [G] COG1445 Phosphotransferase system fructose-specific component IIB
--------------------||-||-|---||||||||----|||||-||||||||||||||||--  2 [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen
||||---||----------|-|--------||||||||-----------|-------------|--  2 [K] COG1476 Predicted transcriptional regulators
--------|----||--|---|---|||||||||||||-|--|||||-|--|--------------  2 [G] COG1482 Phosphomannose isomerase
--|-------------|----------||-|||||||||---||||||-------|---||-|---  2 [L] COG1484 DNA replication protein
----||--|-|--|||-||||-||--|---||||||||||--||||||||||||||||-|||||||  2 [I] COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes
||-|--||-|---||-|--|------|-------|-|--|||-------|||-||---|||||---  2 [L] COG1525 Micrococcal nuclease (thermonuclease) homologs
||||--||||||||||---------|-----|||||------------------------------  2 [I] COG1577 Mevalonate kinase
-----------------|||||--|-||||||--||||----|||||-||||||||---|||||--  2 [K] COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
----|--------||--|||-|----|||-||||||||----|||||--|---------||-||--  2 [IR] COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
---|----||-|---------|---|--------|-||----|||-|-||||-||||||--|----  2 [C] COG1620 L-lactate permease
-----------------|------|---------||||----------------------------  2 [R] COG1647 Esterase/lipase
|||-|||||-------|---|----|----|||||||||-||------------------------  2 [L] COG1658 Small primase-like proteins (Toprim domain)
--|---||--|-|-----||-|----||||||||||||----|||||--|--|--|---|||||||  2 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins
---|----|----------|||-----||-|||||||-----|||-|--|-----|||-||||---  2 [M] COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
---|--||----|-------|----|----|---|-||-------||-|-||-||-|||-------  2 [C] COG1757 Na+/H+ antiporter
--------------------||----||||||||||||----|||||-||||-|||||||||||--  2 [E] COG1760 L-serine deaminase
----||---------------|----|----|--|||---|||||-|-||--|--|---|||||--  2 [O] COG1764 Predicted redox protein, regulator of disulfide bond formation
--|----------------|||----||||-||||||------||-|--||-||||---|||||-|  2 [I] COG1835 Predicted acyltransferases
|-|-|-|||-|||-|-||||||----||||||-|||||----|||||--|-|-|||---|||||||  2 [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family
||||--||---------|---|----|-------||||----------||---------|||--||  2 [P] COG1863 Multisubunit Na+/H+ antiporter, MnhE subunit
---|--|||-|-|||-|--|------|||-|||-||||----|||||-||-----|------||--  2 [H] COG1893 Ketopantoate reductase
--||||--|--|-||--|-|||----|||-|||-||||-|--|||||-||--|--|---|||||--  2 [C] COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family
----||-----|-||----|||----||||||-|||||----|||||--|||||||---||||---  2 [P] COG1914 Mn2+ and Fe2+ transporters of the NRAMP family
------------------|-------|||-||||||||----|||||-||||-||-----------  2 [G] COG1929 Glycerate kinase
-----------|-||----|-|----|||-----|--|----|||-|--|-|---|--||||||--  2 [F] COG1957 Inosine-uridine nucleoside N-ribohydrolase
----------------||||||-----||-||-|||||----|||||-||||||||--||||||||  2 [K] COG1959 Predicted transcriptional regulator
------||-----|------||----||||----|-||----|||||-|||--|||--||---|--  2 [E] COG1984 Allophanate hydrolase subunit 2
|||---||||--|-----------------|---||||----|||||--|-|--------------  2 [R] COG1988 Predicted membrane-bound metal-dependent hydrolases
--|-------------|||||---------||||||||----|||||-||||||||---||||--|  2 [L] COG2003 DNA repair proteins
--------------------||-||-|---||||||||----|||||-||||||||||||||||--  2 [P] COG2011 ABC-type metal ion transport system, permease component
------||-----|------||----||||----|-||----|||-|-|||--|||--||---|--  2 [E] COG2049 Allophanate hydrolase subunit 1
--|||||||-||--|-|----|----|||--|||||||----|||||-||||---|||||||||--  2 [Q] COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism
---------|---|------|---------|||||||-----|||||-||||--------------  2 [P] COG2116 Formate/nitrite family of transporters
---|-------------|||||----|---|--||-||----|||-|-||||||||--||||||--  2 [M] COG2148 Sugar transferases involved in lipopolysaccharide synthesis
---|||------------||-|-----||-|---||------|||||--|-----|---||-||--  2 [P] COG2156 K+-transporting ATPase, c chain
---|-------------|||-------||----||-------|||-|-|----------|-----|  2 [D] COG2161 Antitoxin of toxin-antitoxin stability system
--|-----------------||---|----||||||||----|||||-|-||------|-|--|--  2 [E] COG2195 Di- and tripeptidases
------------------||-|-----||-|---||------|||||-||-----|--|||-||--  2 [T] COG2205 Osmosensitive K+ channel histidine kinase
--||||--|-||----|---|-------------|-|-----------------------------  2 [S] COG2210 Uncharacterized conserved protein
|-||--||---------|---|----|-------||||----------||---------|||--|-  2 [P] COG2212 Multisubunit Na+/H+ antiporter, MnhF subunit
---|||------------||-|-----||-|---||------|||||--|-----|--|||-||--  2 [P] COG2216 High-affinity K+ transport system, ATPase chain B
||||||||||||||---|||||----|||-|-||||||----|||||-||-||--|--|||||--|  2 [R] COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold
-------|------|--|--||----|---||||||||----|||||-||||-|||---|||----  2 [F] COG2233 Xanthine/uracil permeases
-------||----||--|-|||----||||||--||||----|||||-||||---|---|||||--  2 [I] COG2267 Lysophospholipase
----------------------||-------||-|-|-----|||||-||||------|-----||  2 [G] COG2271 Sugar phosphate permease
-||---------------||-|---|-||--|--|-||-----------|-----|----------  2 [S] COG2314 Predicted membrane protein
--------|----|-|---|||---||---|---||||-----------|---------|||||--  2 [S] COG2340 Uncharacterized protein with SCP/PR1 domains
--------------------||----|||-||||||||----------------------------  2 [S] COG2357 Uncharacterized protein conserved in bacteria
-------------||-----||---------|--||-|----||||-----|-------||||---  2 [G] COG2376 Dihydroxyacetone kinase
----------|-|--------|----|-----||||||---------------------||||---  2 [R] COG2514 Predicted ring-cleavage extradiol dioxygenase
------------------||--------------|-|------------|-----|--||--|--|  2 [V] COG2602 Beta-lactamase class D
----||||--||--------------|---||||||||----|||||-|----------||--|--  2 [G] COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase
|------------||-----|-----|||-|--|||-|----|||||-|-|||-----|-------  2 [S] COG2966 Uncharacterized conserved protein
--------------------|---------|-||||||----------||--|--|----------  2 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain
--|----------------|------|----|--||------|||||-||---------|||||--  2 [R] COG3153 Predicted acetyltransferase
-------------------|------|----||||||-----|||-|--|---------||-||--  2 [S] COG3237 Uncharacterized protein conserved in bacteria
--------------------|---------|---|-||----|||-|-|-----------|-----  2 [S] COG3314 Uncharacterized protein conserved in bacteria
-|-|----|-------|---------|-------||---------|------|--------|||--  2 [L] COG3316 Transposase and inactivated derivatives
--------------------------|---|-||||-|-||-|||-|-|--|--------------  2 [G] COG3414 Phosphotransferase system, galactitol-specific IIB component
||||||||||||||||---------|-----||||||--------|-----------------|--  2 [I] COG3425 3-hydroxy-3-methylglutaryl CoA synthase
--|---------------------------||-||||-----------|-----------------  2 [Q] COG3527 Alpha-acetolactate decarboxylase
------------------||-|----||||||||||||-|--------------------------  2 [D] COG3599 Cell division initiation protein
|------------||-----|-----|||-|--|||-|----|||||-|-|||-----|-------  2 [S] COG3610 Uncharacterized conserved protein
---|------|--------||-----|----|--|--|-|||||||---|---------||-||--  2 [P] COG3639 ABC-type phosphate/phosphonate transport system, permease component
--------------------|---|-------|-||-|----------------------------  2 [R] COG3641 Predicted membrane protein, putative toxin regulator
---|----|----------------------|||||||----------------------------  2 [S] COG3679 Uncharacterized conserved protein
------||----------||------|||||||||----------------------------|--  2 [K] COG3682 Predicted transcriptional regulator
--|--------------|--------|||-|---||||-----------|-----|---||-||--  2 [S] COG3832 Uncharacterized conserved protein
--------------------||--------|---|||-----------------------------  2 [S] COG3878 Uncharacterized protein conserved in bacteria
------------------------------||||||||----------------------------  2 [L] COG3935 Putative primosome component and related proteins
--------------------------|---|--||-||----------------------------  2 [M] COG3944 Capsular polysaccharide biosynthesis protein
------||------------------|---|---|-||----------------------------  2 [S] COG3949 Uncharacterized membrane protein
-------------------|-------||----||------------------------|-----|  2 [S] COG4115 Uncharacterized protein conserved in bacteria
------------------------------|---|----------------------------|--  2 [KT] COG4219 Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component
--------------------|---------||||||||----------------------------  2 [S] COG4224 Uncharacterized protein conserved in bacteria
------------------------------|--||-||----------------------------  2 [GM] COG4464 Capsular polysaccharide biosynthesis protein
----------------------------------|-|-----|--------|--------------  2 [P] COG4594 ABC-type Fe3+-citrate transport system, periplasmic component
-------------------------------|-||--|----------------------------  2 [S] COG4652 Uncharacterized protein conserved in bacteria
--------------------|---|-|||||---||||----|||||-||||||||---|||||||  2 [L] COG4974 Site-specific recombinase XerD
-------------------------------||-|||-----------------------------  2 [G] COG4975 Putative glucose uptake permease
|||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||--  2 [E] COG4992 Ornithine/acetylornithine aminotransferase
----------------------------------||-|----------------------------  2 [M] COG5386 Cell surface protein
--------------------|-----|---||--|-------------------------------  2 [S] COG5438 Predicted multitransmembrane protein
-------------------|--------------|-||----------------------------  2 [S] COG5609 Uncharacterized conserved protein
|||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||--  1 [E] COG0002 Acetylglutamate semialdehyde dehydrogenase
|||-||--||-|-||-||||-|----|||-||--|||||---|||||--|--||||---|||||--  1 [P] COG0004 Ammonia permease
||||||--|||||||-|-||||----|||||---||||----||||||||--||||---|||||--  1 [H] COG0007 Uroporphyrinogen-III methylase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0008 Glutamyl- and glutaminyl-tRNA synthetases
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0012 Predicted GTPase, probable translation factor
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0013 Alanyl-tRNA synthetase
||||||||||||-||-||||||----||||||||||||----||||||||||||||||||||||--  1 [F] COG0015 Adenylosuccinate lyase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0016 Phenylalanyl-tRNA synthetase alpha subunit
||||||||||||||||--||||--||----|||||||||||||||||||-|||-------------  1 [J] COG0017 Aspartyl/asparaginyl-tRNA synthetases
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0018 Arginyl-tRNA synthetase
||||||||||||||||||||||||||||||||||||||----||||||||||||||||||||||||  1 [I] COG0020 Undecaprenyl pyrophosphate synthase
-------------|||||||-||||-||||||||||||||||||||||||||||||||||||||--  1 [G] COG0021 Transketolase
||||||||||||||||||||||||||||||-|||||||||||||||||||||||||||||||||||  1 [J] COG0024 Methionine aminopeptidase
---|||----||-||-||||-|----||||-|||||||----|||||-||||||||---|||||--  1 [F] COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase
|--|---|--|||||-||||||--|-|||-|||||||||||||||||-||||-|||--||||||--  1 [F] COG0035 Uracil phosphoribosyltransferase
-|--||-------||||||||||||-||||||||||||||||||||||||||||||||||||||--  1 [G] COG0036 Pentose-5-phosphate-3-epimerase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [D] COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control
||||----||||-||-||||-|----||||||--||||----|||||||||||||---||||||--  1 [E] COG0040 ATP phosphoribosyltransferase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase
|||||||||||||||-||||||----||||||||||||----|||-|--|--|--|||||||||--  1 [F] COG0044 Dihydroorotase and related cyclic amidohydrolases
||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||--||||||||  1 [C] COG0045 Succinyl-CoA synthetase, beta subunit
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0048 Ribosomal protein S12
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0049 Ribosomal protein S7
---------|---||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0050 GTPases - translation elongation factors
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0051 Ribosomal protein S10
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0052 Ribosomal protein S2
||||---||||||||-||||||---||||-||||||||----|||||-||-|---|--||||||||  1 [P] COG0053 Predicted Co/Zn/Cd cation transporters
||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG0054 Riboflavin synthase beta-chain
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0055 F0F1-type ATP synthase, beta subunit
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0056 F0F1-type ATP synthase, alpha subunit
|||----|||||-|--||||-|----||||||-|||||----||||||||||||||||||||||--  1 [EH] COG0059 Ketol-acid reductoisomerase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0060 Isoleucyl-tRNA synthetase
|||||||||||||||||||||---|||||||||||||||-||||||||||||||||||||||||||  1 [G] COG0061 Predicted sugar kinase
||||||||||||||||||||-|----||||||--|||-----|||||-||--||||||||||||--  1 [G] COG0063 Predicted sugar kinase
||||----||-||||-||||||||||||||||||||||||||-------|---|||||||||||||  1 [J] COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog)
||||--||||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0065 3-isopropylmalate dehydratase large subunit
|||---||||||-||-||||-|----||||||-|||||----||||||||||||||--||||||--  1 [E] COG0066 3-isopropylmalate dehydratase small subunit
|||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||--  1 [E] COG0067 Glutamate synthase domain 1
|||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||--  1 [E] COG0070 Glutamate synthase domain 3
|||||||||||||||-||||-|-----||||---|-||----||||||||--|--|---|||||||  1 [O] COG0071 Molecular chaperone (small heat shock protein)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0072 Phenylalanyl-tRNA synthetase beta subunit
||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||--||||||||  1 [C] COG0074 Succinyl-CoA synthetase, alpha subunit
||||||||||||||--||||-|--------||--|-||--------|-||------||-||-||--  1 [E] COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase
||||||--||||-||-||||-|----||||||-|||||----|||-||||||||||--||||||--  1 [E] COG0077 Prephenate dehydratase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0080 Ribosomal protein L11
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0081 Ribosomal protein L1
||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||--  1 [E] COG0082 Chorismate synthase
-|-|||||-||||||-||||-|----||||||-|||||----|||||||-|||---|||-------  1 [E] COG0083 Homoserine kinase
|||---||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0084 Mg-dependent DNase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0087 Ribosomal protein L3
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0088 Ribosomal protein L4
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0089 Ribosomal protein L23
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0090 Ribosomal protein L2
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0091 Ribosomal protein L22
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0092 Ribosomal protein S3
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0093 Ribosomal protein L14
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0094 Ribosomal protein L5
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0096 Ribosomal protein S8
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0097 Ribosomal protein L6P/L9E
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0098 Ribosomal protein S5
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0099 Ribosomal protein S13
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0100 Ribosomal protein S11
|||||||||||--||||||||||||||||||||||||||-||||||||||||||||||||||||||  1 [J] COG0101 Pseudouridylate synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0102 Ribosomal protein L13
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0103 Ribosomal protein S9
||||||||||||-||-||||||----||||||||||||----||||||||||||||||||||||--  1 [F] COG0104 Adenylosuccinate synthase
|||||||||||||||||-||-||||||||||--|||||----|||||-||||||||||||||||||  1 [F] COG0105 Nucleoside diphosphate kinase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0107 Imidazoleglycerol-phosphate synthase
||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase
---|||--|-|||||-|-||-|----||||----||||----||||||-|--|--|---|||||||  1 [O] COG0109 Polyprenyltransferase (cytochrome oxidase assembly factor)
||||||||||||||||||||-|||||||||||||||||-|||||||||||||||||||||||||||  1 [E] COG0112 Glycine/serine hydroxymethyltransferase
||||||--|||||||-|-||||||--|||||---||||----|||||-||-|||||||||||||||  1 [H] COG0113 Delta-aminolevulinic acid dehydratase
--||------|||||---|--|||--||||----||||----|||||-||||||||||||||||||  1 [C] COG0114 Fumarase
-|----|||||-|-----|-||--------||||||||----||||||||||||||----------  1 [L] COG0116 Predicted N6-adenine-specific DNA methylase
-------------||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG0117 Pyrimidine deaminase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0118 Glutamine amidotransferase
||||||||||||||||--||-|||||----||||||------||||||||||||||---|||||--  1 [G] COG0120 Ribose 5-phosphate isomerase
||||--|||||||||||-||-|------------|-||----------||---|||---|||||--  1 [BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0124 Histidyl-tRNA synthetase
||||||||||||||||||||||||||||||-|||||||||||||||||||||||||||||||||||  1 [F] COG0125 Thymidylate kinase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||--  1 [G] COG0126 3-phosphoglycerate kinase
||||||||||||||||||||||||||||||||||||||----|||||-||||||||--||||||--  1 [F] COG0127 Xanthosine triphosphate pyrophosphatase
||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||--  1 [E] COG0128 5-enolpyruvylshikimate-3-phosphate synthase
|||----||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1 [EG] COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase
||||||||||||||||||||||||||||||||||||||||--||||||||||||||--||||||||  1 [J] COG0130 Pseudouridine synthase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0131 Imidazoleglycerol-phosphate dehydratase
-|-----------|--|-|||--|--|||||---|-||----||||||||||||||||||-|||--  1 [H] COG0132 Dethiobiotin synthetase
||||---|||---||-|||||||---||||||-|||||----||||||||||||||||||||||--  1 [E] COG0133 Tryptophan synthase beta chain
||||||-||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1 [E] COG0134 Indole-3-glycerol phosphate synthase
||||||-||||||||-||||-||---|---||-|||||----||||||||||||||||||||||--  1 [E] COG0135 Phosphoribosylanthranilate isomerase
|||||-|||||||||-||||-|||--||||||-|||||----||||||||||||||||||||||||  1 [E] COG0136 Aspartate-semialdehyde dehydrogenase
||||||--||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0137 Argininosuccinate synthase
--||||--|----||-||||||----||||||-|||||----||||||||||||||--||||||--  1 [F] COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0139 Phosphoribosyl-AMP cyclohydrolase
||||-----|||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0140 Phosphoribosyl-ATP pyrophosphohydrolase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0141 Histidinol dehydrogenase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0143 Methionyl-tRNA synthetase
-|-|--||||||||||-|||||||--|||-||||||||----|||||-||||||||--||||||--  1 [J] COG0144 tRNA and rRNA cytosine-C5-methylases
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||--  1 [G] COG0148 Enolase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||--  1 [G] COG0149 Triosephosphate isomerase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0150 Phosphoribosylaminoimidazole (AIR) synthetase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||||||||||--  1 [F] COG0151 Phosphoribosylamine-glycine ligase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||||  1 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase
||||----|||||||-||||||||||||||||||||||||||---|---|---|||||||||||||  1 [J] COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases
||||||-||||||||-||||-||---||||||-|||||----||||||||||||||||||||||--  1 [E] COG0159 Tryptophan synthase alpha chain
--||||||--|||||----|-|----|||||---|-||----|||||-|||----|---||||---  1 [E] COG0160 4-aminobutyrate aminotransferase and related aminotransferases
-|-----------||-|---||-|--|||||---|-||----||||||||||||||||||||||--  1 [H] COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0162 Tyrosyl-tRNA synthetase
||||||||||||||||||||||||-|||||||||||||----|||||-||||||||||||||||||  1 [L] COG0164 Ribonuclease HII
||||||--||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1 [E] COG0165 Argininosuccinate lyase
-|-|||----||||||||||||||||||||||||||||-|||||||||||||||||||||||||--  1 [G] COG0166 Glucose-6-phosphate isomerase
|||||||||||||||-||||||----||||||||||||----||||||||||||||||||||||--  1 [F] COG0167 Dihydroorotate dehydrogenase
||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||--  1 [E] COG0169 Shikimate 5-dehydrogenase
|||||||||||||||-||||||--||||||||||||||||||||||||||--||||||||||||--  1 [H] COG0171 NAD synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0172 Seryl-tRNA synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0173 Aspartyl-tRNA synthetase
|||||||||||||||-||||-|----||||-|||||||----|||||-||||||||||||||||||  1 [E] COG0174 Glutamine synthetase
-|--||-------||-||||-|||--|||||-||||||----||||||||||-|||||||||||--  1 [G] COG0176 Transaldolase
||||||||||||||||||||||||||||||||||||||----||||||||||||||||||||||||  1 [L] COG0177 Predicted EndoIII-related endonuclease
|-||------------|||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG0178 Excinuclease ATPase subunit
|||||||||||||||---||-|----||||----||||----|||||-||-|-|||--||||||--  1 [Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0180 Tryptophanyl-tRNA synthetase
||||||--|||||||-|-||||||--|||||---||||----||||||||-|||||||||||||||  1 [H] COG0181 Porphobilinogen deaminase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0184 Ribosomal protein S15P/S13E
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0185 Ribosomal protein S19
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0186 Ribosomal protein S17
--||||----||-||-|||||||||||||||||||||||||||||||||||||-||||||||||||  1 [H] COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase
-------------||-||||-|--||||||||||||||||||||||||||||-||||||-||||--  1 [G] COG0191 Fructose/tagatose bisphosphate aldolase
-------------||-||||||--||||||||||||||||||||||||||||||||||||||||--  1 [H] COG0192 S-adenosylmethionine synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0193 Peptidyl-tRNA hydrolase
-------------|||||||||||--||||||||||||||||||||||||||||||||||||||||  1 [F] COG0194 Guanylate kinase
|||||||||||||---||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0195 Transcription elongation factor
-------------||-|||||||||-||||||||||||||||||||||||||||||||||||||--  1 [H] COG0196 FAD synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0197 Ribosomal protein L16/L10E
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0198 Ribosomal protein L24
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0200 Ribosomal protein L15
||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0203 Ribosomal protein L17
-------------||||||||||||||||||||||||||||||||||-||||||||||||||||||  1 [I] COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase
-------------||||||||||||||||||||||||||||||||||||-|||------||-|---  1 [G] COG0205 6-phosphofructokinase
||||||||||------||||||--||||||||||||||-|||||||||||||||||||||||||||  1 [D] COG0206 Cell division GTPase
|||-----||---|||----||----||||||||||||-|||||||||||||||||---|||||--  1 [F] COG0207 Thymidylate synthase
---|-------|-||||-|-|||||-||||||||||||-|||||||||||||||||||||-|-|||  1 [F] COG0208 Ribonucleotide reductase, beta subunit
|-|||||||-|||||||||-|||||-||||||||||||-|||||||||||||||||||||||||||  1 [F] COG0209 Ribonucleotide reductase, alpha subunit
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0211 Ribosomal protein L27
|--|-----||||||-|-|||||||-||||||-|||||--|||||||-||||||||||||||||||  1 [H] COG0212 5-formyltetrahydrofolate cyclo-ligase
-||---|||--------|---|-----||-||-||||||||||||-|-|------|---||-|---  1 [F] COG0213 Thymidine phosphorylase
|||||||||||||||--|--||----|||||--|||||------------||--------------  1 [H] COG0214 Pyridoxine biosynthesis enzyme
--|||||||-||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0215 Cysteinyl-tRNA synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0216 Protein chain release factor A
-------------||-|||||||||||||||||||||||||||||||-||||||||||||||||||  1 [S] COG0217 Uncharacterized conserved protein
-|||--||||---|--||--|---------||||||||||||||||||||||||||||||||||||  1 [R] COG0218 Predicted GTPase
------------------||||||--|||||||||-|||||||||||-||||||||--||||||--  1 [J] COG0219 Predicted rRNA methylase (SpoU class)
-------------||||||||||||-||||||||||||||||||||||||||||||||||||||||  1 [R] COG0220 Predicted S-adenosylmethionine-dependent methyltransferase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0222 Ribosomal protein L7/L12
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0223 Methionyl-tRNA formyltransferase
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0224 F0F1-type ATP synthase, gamma subunit
||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||--  1 [P] COG0226 ABC-type phosphate transport system, periplasmic component
-------------||-|||||||||||||-|||||||||||||||||||||||||||||-||||||  1 [J] COG0227 Ribosomal protein L28
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0228 Ribosomal protein S16
|-||---------||---||||--|-|||-||||||||-||||||||-||||||||||||||||--  1 [O] COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase
-------------||-||||-||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0230 Ribosomal protein L34
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0233 Ribosome recycling factor
--|----------||-||||||||||||||||||||||--||||||||||||||||||||||||||  1 [O] COG0234 Co-chaperonin GroES (HSP10)
||||||||||||||||||||||||||||||||||||||-|||||||||||||||||||||||||||  1 [H] COG0237 Dephospho-CoA kinase
-------------||-|||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0238 Ribosomal protein S18
|-------|----|||||||||||||||||||||||||||--|||||-||||||||||||||||||  1 [C] COG0240 Glycerol-3-phosphate dehydrogenase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0244 Ribosomal protein L10
-------------|---|--------|---||-||-||-||-||||||||-|---|---|||||--  1 [G] COG0246 Mannitol-1-phosphate/altronate dehydrogenases
|||||||||||||-|-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0250 Transcription antiterminator
---|--||--|||||-||||||----||||||||||||----||||||||||||||||||||||--  1 [J] COG0251 Putative translation initiation inhibitor, yjgF family
|||||||||||||||-----||----||||||||||||----|||||-|||-||||||||-|----  1 [EJ] COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D
||------||------|||||-||--|||||---||||----||||||||||||||||||||||||  1 [E] COG0253 Diaminopimelate epimerase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0254 Ribosomal protein L31
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0255 Ribosomal protein L29
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0256 Ribosomal protein L18
-------------||-||||-||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0257 Ribosomal protein L36
------------|-|||-||||||--||||----|-|||||||||||||||||-||||||||||||  1 [E] COG0260 Leucyl aminopeptidase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0261 Ribosomal protein L21
--|----------|||-|--||||--||||||||||||||||||||||||||||||---|||||-|  1 [H] COG0262 Dihydrofolate reductase
--------------|-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0264 Translation elongation factor Ts
------------------||-|----||||-||||||||||||||||-||||||||---|||||-|  1 [L] COG0266 Formamidopyrimidine-DNA glycosylase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0268 Ribosomal protein S20
|||---|||||||-----------------|-|||-|--||-|||-|-|-||--------------  1 [G] COG0269 3-hexulose-6-phosphate synthase and related proteins
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0272 NAD-dependent DNA ligase (contains BRCT domain type II)
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [M] COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis
----||-------||-|-||-|||--||||-|-|||||----|||||-||||||||||||||||||  1 [H] COG0276 Protoheme ferro-lyase (ferrochelatase)
--||-------------||-||--|||||-||||||||||||||||||||||||||-|||||||||  1 [C] COG0280 Phosphotransacetylase
--|||||||-|||||--|||-|----|||-|||-||||----|||||-||||||||--||||||||  1 [C] COG0281 Malic enzyme
--|--------------|||||--|||||-||||||||||||||||||||||-||-|||-|||-||  1 [C] COG0282 Acetate kinase
---------------||||||||||||||||||||||||||||||||-||||||||---|||||||  1 [F] COG0283 Cytidylate kinase
|||||||||||||||-||||||----||||||||||||----||||||||||||||||||||||--  1 [F] COG0284 Orotidine-5'-phosphate decarboxylase
---|||-------||-||||||--|-||||||||||||----||||||||||||||||||||||||  1 [H] COG0285 Folylpolyglutamate synthase
||||||--|||||||-||||-|----||||||-|||||----|||||-||||||||||||||||--  1 [E] COG0287 Prephenate dehydrogenase
|||-----||------||||--||--|||-||-|||||----||||||||||||||||||||||||  1 [E] COG0289 Dihydrodipicolinate reductase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0290 Translation initiation factor 3 (IF-3)
-------------|--||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0291 Ribosomal protein L35
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0292 Ribosomal protein L20
|||||||||||||||-||||||||--||||||||||||----|||||-||||||||||||||||-|  1 [H] COG0294 Dihydropteroate synthase and related enzymes
---|------|-|||--|---|---|-||||||||||||||||||||-|-||-------||-||--  1 [F] COG0295 Cytidine deaminase
--||||----|--||-||||||----||||||||||||----|||||-||||||||--||||||--  1 [F] COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN
--|----|---|-|||---||-----||||||||||||-----------|-|---|---||-||--  1 [R] COG0300 Short-chain dehydrogenases of various substrate specificities
|||||||||||||----|------|-----|||||||||||||||||-||||--------------  1 [H] COG0301 Thiamine biosynthesis ATP pyrophosphatase
|||||||||||||---|-||-|----|||||---||||----|||||-||||---|||||||||--  1 [H] COG0303 Molybdopterin biosynthesis enzyme
-------------||-||||||||--||||||||||||----||||||||||||||||||||||||  1 [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0305 Replicative DNA helicase
||||||||||||-|---|-|-|||--|||||---||||----||||||||||-||||||||-|---  1 [P] COG0306 Phosphate/sulphate permeases
---|---------||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG0307 Riboflavin synthase alpha chain
|||||||||||||||--|---|----|||||--|||||------------||--------------  1 [H] COG0311 Predicted glutamine amidotransferase involved in pyridoxine biosynthesis
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [R] COG0313 Predicted methyltransferases
|||||||||-|||---|-||-|----|||-----||||----|||||-||||---|||||||||--  1 [H] COG0314 Molybdopterin converting factor, large subunit
|||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||--  1 [H] COG0315 Molybdenum cofactor biosynthesis enzyme
--|----------||-|-||-|----||||----|-||----||||||||||||||---|||||||  1 [S] COG0316 Uncharacterized conserved protein
----------------||||||---||||||||||||||-|||||||-||||||||||||||||-|  1 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [R] COG0319 Predicted metal-dependent hydrolase
---|------|||||-|-||-|||--||||----|-||----||||||||||||||---|||||||  1 [H] COG0320 Lipoate synthase
|-||------------|||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG0322 Nuclease subunit of the excinuclease complex
--||---------|||||||||||||----||||||||----||||||||||||||---|||||||  1 [L] COG0323 DNA mismatch repair enzyme (predicted ATPase)
-------------||-||||||||||||||||||||||----||||||||||||||||||||||||  1 [J] COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase
--|----------||-||||||----||||||||||||----||||||||||||||||||||||--  1 [R] COG0325 Predicted enzyme with a TIM-barrel fold
---|------|--||---||-|--|-||||----||||----|||||-||||||||||||||||||  1 [L] COG0328 Ribonuclease HI
-------------||-||||||||--||||||||||||----|||||-||||||||||||||||||  1 [I] COG0331 (acyl-carrier-protein) S-malonyltransferase
----------------|-||||||---||-||||||||----|||||-||||||||||||||||||  1 [I] COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III
-------------||-||||||||||----||||||||||||||||||||||||||||||||||||  1 [J] COG0333 Ribosomal protein L32
--|||||||-|||||--|||||||--|---|--|||||----|||||--|||-|||||--||-|--  1 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0335 Ribosomal protein L19
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0336 tRNA-(guanine-N1)-methyltransferase
----||-|--|||||--|||||||--||||||||||||----||||||||||||||||||||||--  1 [E] COG0337 3-dehydroquinate synthetase
||||--|||--|-||-|||||||||-||||||||||||----|||||-||||||||||||||||||  1 [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase
||||--||-|------|||||||||||||||---||||-|--|||||-||||||||||||||||||  1 [U] COG0341 Preprotein translocase subunit SecF
||||--||-|------|||||||||||||||---||||-|--|||||-||||||||||||||||||  1 [U] COG0342 Preprotein translocase subunit SecD
|||||||||||||-||||||||||-||---||||||||----||||||||||||||||||||||||  1 [J] COG0343 Queuine/archaeosine tRNA-ribosyltransferase
----------------||||||--------|||||||||||||||||-||||-|||||||||||--  1 [S] COG0344 Predicted membrane protein
|-|-||----|||||-||||-|--|-||||||||||||----|||||-||||||||||||||||--  1 [E] COG0345 Pyrroline-5-carboxylate reductase
||||||||||||||--||-||-|||-||||||-|||||-|--|||||-||||||||||||||||-|  1 [L] COG0350 Methylated DNA-protein cysteine methyltransferase
--|-|||||----||-|-||||----||||||-|||||----|||||-||||||||||||||||--  1 [H] COG0352 Thiamine monophosphate synthase
----------------|-|||||||-||||||||||||||--|||||-||||||||||||||||||  1 [L] COG0353 Recombinational DNA repair protein (RecF pathway)
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0355 F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit)
--|----------|--|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0356 F0F1-type ATP synthase, subunit a
----------------||||||--|||||||||||||||||||||||-||||||||||||||||||  1 [M] COG0357 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division
|||||||||||||---||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0358 DNA primase (bacterial type)
--------------|-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0359 Ribosomal protein L9
-------------||-|||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0360 Ribosomal protein S6
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0361 Translation initiation factor 1 (IF-1)
-------------|||-|||--||||||||-|-||||-----|||||||-||-||----||||---  1 [G] COG0362 6-phosphogluconate dehydrogenase
-------------|||-||||-||||||||||||||||-|--|||||-||||||||||-|||||--  1 [G] COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase
-------------|||||||-||||||||--|-||||-----||||||||||||||||-|||||--  1 [G] COG0364 Glucose-6-phosphate 1-dehydrogenase
-------------|||--||--||----------|-||----||||||||--|||----|-|-|--  1 [P] COG0369 Sulfite reductase, alpha subunit (flavoprotein)
|-||||--|-|||||-||||-|----||||-|--||||----|||||-||-|||||||||||||||  1 [C] COG0372 Citrate synthase
||||||--|||||---|-||||||--|||||---||||----|||||-||-||||||||-------  1 [H] COG0373 Glutamyl-tRNA reductase
|||-----||----|-|-||||----|||-----|--||---|||||--||----||||||||---  1 [OK] COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase
--|----------|--|-||------|--|----|-||----|||||--|---|||---|||||--  1 [R] COG0385 Predicted Na+-dependent transporter
|-|||||||-|||||-||||-|--|-|||||--|||||----|||||-||--||||||||||||--  1 [R] COG0388 Predicted amidohydrolase
-||-------------||||-------||-----|-|-----|||-|--------|----------  1 [R] COG0390 ABC-type uncharacterized transport system, permease component
||||----||---|--||||-|----||||||||||||----|||||-|--|--------------  1 [S] COG0391 Uncharacterized conserved protein
||||--||||------||||------|||||---|||-|||||||-|--|--|--|---||||---  1 [S] COG0392 Predicted integral membrane protein
|||||||||||||----|||-||||-||||||||||||----|||||-----|------|||||--  1 [O] COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
--||---------||---||------|||-||||||||----|||---|-----------|--|--  1 [S] COG0398 Uncharacterized conserved protein
-------------||---||-|||-------|--||||----|||----|--|------||||-||  1 [R] COG0400 Predicted esterase
---|||||---||||-||||-|-----|||----||||----|||||--|--|-||---|||||--  1 [E] COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain
---|||||---||||-||||-|-----|||----||||----|||||--|--||||---|||||--  1 [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase)
----||----||||||--||||----|||-----|-||----|||-|-||--||||||-||-||--  1 [E] COG0405 Gamma-glutamyltransferase
--|-||-------||-|-||-|||--||||----||||----|||||-||-|||||||||||||||  1 [H] COG0407 Uroporphyrinogen-III decarboxylase
---|--||--|||||-||||-|----|||||---||||----||||||||--||||||||||||--  1 [H] COG0413 Ketopantoate hydroxymethyltransferase
-------------||-||||-|----|||||---||||----||||||||--||||||||||||--  1 [H] COG0414 Panthothenate synthetase
|-||-------|-|----||------|-----|-||------||||||||----|----|--||--  1 [L] COG0415 Deoxyribodipyrimidine photolyase
----------------||||||||------|||||||||||||||||-||-|-|||||||||||--  1 [I] COG0416 Fatty acid/phospholipid biosynthesis enzyme
||||||||||||||||||||||--||----||--|||-----|||||-||----------------  1 [L] COG0419 ATPase involved in DNA repair
||||||||||||||||-----|--|||||||---|---||||------------------------  1 [J] COG0423 Glycyl-tRNA synthetase (class II)
|||---||||--|||-||||-|----||||||-|||||----||||||||||-|||--||||||--  1 [E] COG0440 Acetolactate synthase, small (regulatory) subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0441 Threonyl-tRNA synthetase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0442 Prolyl-tRNA synthetase
|-||||-------|||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0443 Molecular chaperone
-------------||-||||||||||----||||||||||||||||||||||||||||||||||||  1 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division
---|----|---------||------||||-|--|||-----|||||-|-||--------------  1 [H] COG0447 Dihydroxynaphthoic acid synthase
||||||||-||||||||||||||||-||||||||||||----||||||||||||||||||||||--  1 [M] COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains
|||-|||||-|||||||||||||||--|||-||-||||----||||||||-||--|||||||||||  1 [O] COG0450 Peroxiredoxin
|||||||||||||||-||||||---|||||||||||||----|||||-||||||||||||||||--  1 [H] COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase
||||||--||||-||-||||||----||||||||||||----||||||||-|||||||||||||--  1 [EF] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
||||||||||||||||||||||||||||||||||||||--||||||||||||||||||||||||||  1 [O] COG0459 Chaperonin GroEL (HSP60 family)
|||||||||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1 [E] COG0460 Homoserine dehydrogenase
|||||||||||||||-||||||-|--||||||||||||----||||||||||||||||||||||--  1 [F] COG0461 Orotate phosphoribosyltransferase
|||||||||||||||-||||||--||||||||||||||||||||||||||||||||||||||||-|  1 [FE] COG0462 Phosphoribosylpyrophosphate synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0465 ATP-dependent Zn proteases
|||||||||||||||||||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG0468 RecA/RadA recombinase
-|||||||--||||||-|||||||-|||||||||||||||||||||||||||||||--||||||--  1 [G] COG0469 Pyruvate kinase
|||||||||||||||||||||||||-||||-|||||||||||||||||||||||||||||||||||  1 [L] COG0470 ATPase involved in DNA replication
|||---||||||-||-||||-|----||||||--||||----||||||||||||||--||||||||  1 [CE] COG0473 Isocitrate/isopropylmalate dehydrogenase
|||-|||||-|||||-|-||-|---|-|||||--||||----|||||-|||-||||||||||||||  1 [P] COG0475 Kef-type K+ transport systems, membrane components
|-|||||||-|||||||-||||----|||||--|||||----|||||-||||||||||||||||--  1 [H] COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||||||||||||  1 [C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0480 Translation elongation factors (GTPases)
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [M] COG0481 Membrane GTPase LepA
-------------||-||||||||-|||||||||||||||||||||||||||||||||||||||||  1 [J] COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain
|-||||-------|||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain
-------------||-||||||||||----||||||||||||||||||||||||||||||||||||  1 [R] COG0486 Predicted GTPase
--|-||||--|-|||||||--|--|-||||||--||||----|||||-||--|--|--||||||||  1 [ER] COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0495 Leucyl-tRNA synthetase
----------------|-||||--|-||||||||||||----|||||-||||||||||||||||||  1 [L] COG0497 ATPase involved in DNA repair
|||||||||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1 [E] COG0498 Threonine synthase
|||------|---||-|||||--|--|||||---|-||----||||||||||||||||||-|||--  1 [H] COG0502 Biotin synthase and related enzymes
||||||||||||||||||||-|||||||||||||||||||--||||||||||||||||||||||||  1 [F] COG0504 CTP synthase (UTP-ammonia lyase)
||||||--||||-||-||||||----||||||||||||----||||||||-|||||||||||||--  1 [EF] COG0505 Carbamoylphosphate synthase small subunit
---|---------||---||-|----|||-----|-||----|||||--|-|-|||||||||||--  1 [E] COG0506 Proline dehydrogenase
-|-----------||----|-|||-|-||-||||||||-|--|||||||||||||---|||||---  1 [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member
-------------||-----|---|------|||||||-||||||||-|-|-----------|---  1 [M] COG0510 Predicted choline kinase involved in LPS biosynthesis
|||||||||||||||-||||||-|-|||||||||||||----|||||-||||||||||||||||--  1 [F] COG0518 GMP synthase - Glutamine amidotransferase domain
|||||||||||||||-||||||-|-|||||||||||||----|||||-||||||||||||||||--  1 [F] COG0519 GMP synthase, PP-ATPase domain/subunit
|-||--||-|-||-|--||||||||||||||||||||||||||||||-|||||--|||||||||--  1 [E] COG0520 Selenocysteine lyase
|||||||||||||---|--|-|----|||||---||||----|||||-||||---|||||||||--  1 [H] COG0521 Molybdopterin biosynthesis enzymes
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0522 Ribosomal protein S4 and related proteins
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0525 Valyl-tRNA synthetase
|||||||||||||---||||||||||||||||||||||||||||||||||||||||||||||||||  1 [F] COG0528 Uridylate kinase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0532 Translation initiation factor 2 (IF-2; GTPase)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0533 Metal-dependent proteases with possible chaperone activity
||||--|||---|||-|||-||--|||||-|||||||||||||||||-||||||||||||||||--  1 [V] COG0534 Na+-driven multidrug efflux pump
|||||||||||||---||||-|-----||-||--|-||-----------|-----|----|-|---  1 [R] COG0535 Predicted Fe-S oxidoreductases
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [R] COG0536 Predicted GTPase
|||||||||-|||||||-||||||-|||||||||||||||||||||||||||||||||||||||||  1 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
---|||--|-|||||-||||-|-----||--|--||||----|||||--|-|---|||-|||||--  1 [C] COG0538 Isocitrate dehydrogenases
-------------||-||||||||||||||||||||||-|--||||||||||||||||||||||||  1 [J] COG0539 Ribosomal protein S1
|||||||||||||||-||||||----||||||||||||----||||||||--||||||||||||--  1 [F] COG0540 Aspartate carbamoyltransferase, catalytic chain
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0541 Signal recognition particle GTPase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)
||||||-||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1 [E] COG0547 Anthranilate phosphoribosyltransferase
|||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||-|  1 [E] COG0548 Acetylglutamate kinase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0552 Signal recognition particle GTPase
---|||-||--|||--||||||---|||||||||||||-||||||||-|||||--|---|||||--  1 [C] COG0554 Glycerol kinase
|-||------------|||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG0556 Helicase subunit of the DNA excision repair complex
---|---------||||||||||||-|---||||||||||||||||||||||||||||||||||--  1 [K] COG0557 Exoribonuclease R
|-|||||||-|||||||||||-|||||||||||||||||||||||||-||||||||||||||||||  1 [I] COG0558 Phosphatidylglycerophosphate synthase
--||--|||----|||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [F] COG0563 Adenylate kinase and related kinases
-------------||------|||--||||----|-||----||||||||||||||---|||||||  1 [C] COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0571 dsRNA-specific ribonuclease
---|---------||--|||-|-|||----|||||||||-|||||||-|-||--------------  1 [F] COG0572 Uridine kinase
||||---||||||---||||-|---||||||||||||||-|||||||-|-|||--|--||||||--  1 [P] COG0573 ABC-type phosphate transport system, permease component
|||||||||||||||||||||||||||||||||||||||||||||||-||||||||||||||||||  1 [I] COG0575 CDP-diglyceride synthetase
|-||||-------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0576 Molecular chaperone GrpE (heat shock protein)
---|||-----|-|||--|--|---|||||-|||||||----|||||-|||||--|---||||---  1 [C] COG0578 Glycerol-3-phosphate dehydrogenase
|-------|--|-|||-||-||---|----||||||||-|||||||||-||||--|---|||||--  1 [G] COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)
||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||--  1 [P] COG0581 ABC-type phosphate transport system, permease component
----||-----|------||-|--||||||||--||||----|||||||||||||||||--|||--  1 [S] COG0586 Uncharacterized membrane-associated protein
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0587 DNA polymerase III, alpha subunit
--|----------||-----|-||||||||||||||------||||||--||||||----||||--  1 [G] COG0588 Phosphoglycerate mutase 1
--|----------||||-||-|||--||||||-|||||----||||||||||||||---|||||||  1 [FJ] COG0590 Cytosine/adenosine deaminases
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)
----------------||||-|||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG0593 ATPase involved in DNA replication initiation
-----------------||||||||||||||||||||||||||||||||||||||||||-||||||  1 [J] COG0594 RNase P protein component
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [MU] COG0597 Lipoprotein signal peptidase
-||-----||-------|||||||--|---|--||-||----||||---|||---|---|||||--  1 [P] COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component
|||||||||||||---|-||----------|---|-||----|||||-||||||||||||||||||  1 [R] COG0603 Predicted PP-loop superfamily ATPase
||||||||||||----|||||||||||---||||||||----|||||-||||||||||||||||||  1 [L] COG0608 Single-stranded DNA-specific exonuclease
||||---||----------|-----------||-||--|||-------||||||--|||-||-|-|  1 [V] COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
|||||||||||||||||--------------|--|||----------------------------|  1 [MI] COG0615 Cytidylyltransferase
-------------|||||||||||||||||||||||||----||||||||||||||||||||||||  1 [J] COG0617 tRNA nucleotidyltransferase/poly(A) polymerase
-|||--|||||-|---||||||--|||||-||||||||||||------|-----------------  1 [R] COG0618 Exopolyphosphatase-related proteins
|||||||||||||||-||-----|--||||-|-|||||----||||||||||||||--||--||--  1 [E] COG0620 Methionine synthase II (cobalamin-independent)
||||--|||||||||--|--|---|----|||||||||-||||||||-||----------------  1 [R] COG0622 Predicted phosphoesterase
----------------|-||-|||---|||-|--||||----|||-||-|||-|||||||||||||  1 [I] COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH)
-------------|----||------||||-|||||------|||||--|||-|||---|||||--  1 [R] COG0627 Predicted esterase
-----|-------||-|-||-|||--||||||||||||||||-------|--|--||--|--|---  1 [T] COG0631 Serine/threonine protein phosphatase
-----------------||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG0632 Holliday junction resolvasome, DNA-binding subunit
----------------||--||----||||||-|||||||||||||||||||||||---|||||--  1 [F] COG0634 Hypoxanthine-guanine phosphoribosyltransferase
----------------|||||||||||||-|||||||||---||||||||||||||||||||||||  1 [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases
||||||||||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [C] COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K
--|-|||---||-||--|||-|||--|||||||-||||-|--|||||-||||||||---|||||--  1 [R] COG0637 Predicted phosphatase/phosphohexomutase
-----------------|||||----|||||---||||----|||||-||-----|---|||||--  1 [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain
---|--|||--||||-||--|-----|||--|||||||----|||||--|--------||||||||  1 [G] COG0647 Predicted sugar phosphatases of the HAD superfamily
||||||||--||||||||----||---||||---|||||||||||||||-----------------  1 [L] COG0648 Endonuclease IV
|-||---------|||--||||--|-||||||||||||----|||||-||||||||||||||||--  1 [O] COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
-------------||---||-|----|||-----|-||----|||||-||-|||||---|||||||  1 [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
|||-----||-|-||-|---||-----||||--|||||----||-||-||--|--|---|||-|-|  1 [R] COG0655 Multimeric flavodoxin WrbA
----------------|||||||||||||-|||||||||||||||||-||||||||||||||||-|  1 [R] COG0658 Predicted membrane metal-binding protein
-------------||||||||||||-|||||||-||||----|||||-||||||||--||||||--  1 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
|||||||||||||-||||||||--|||||-||||||||----||||||||--||||||||||||||  1 [M] COG0668 Small-conductance mechanosensitive channel
----------------||||||--||||||||||||||-|--||||||||||||||||||||||--  1 [H] COG0669 Phosphopantetheine adenylyltransferase
-------------||---||||||-|----|||||||--|--|||||-||||-|||||||||||||  1 [R] COG0670 Integral membrane protein, interacts with FtsH
--------|---|||--||||---|---------|||-----||||---|-|-||---|--|--||  1 [P] COG0672 High-affinity Fe2+/Pb2+ permease
|||||||||||||||-|||||---|--||-||--||-|----|||||-|-------|||-------  1 [C] COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit
||----||--|------|------------|---|-------|||||-||-||--|---||-|---  1 [M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase
||-------|---||-|||||-----|---||--||||----||||--||-||--|--||||||||  1 [R] COG0679 Predicted permeases
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [M] COG0682 Prolipoprotein diacylglyceryltransferase
--|-||||--|||||-||||-|----|---||-|||||----||||||||||||||--||||||--  1 [E] COG0685 5,10-methylenetetrahydrofolate reductase
---|----|-|-|----|||||--||----||||||--|||||||||-||||-|||---|||||--  1 [E] COG0687 Spermidine/putrescine-binding periplasmic protein
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0690 Preprotein translocase subunit SecE
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG0691 tmRNA-binding protein
-------------|||----||||-|||||-||||||||||||||||||||||||||||||-----  1 [L] COG0692 Uracil DNA glycosylase
---|----|----||---||--||----------||||----|||||||||||---||||||||||  1 [O] COG0694 Thioredoxin-like proteins and domains
|-||----|----|||-|||-|----|||||||||||-----|||||-||||||||---|||||||  1 [O] COG0695 Glutaredoxin and related proteins
--||-----------|--||----------|---|||||||||||||-||------||||------  1 [G] COG0696 Phosphoglyceromutase
-------------|||--||-|-----||-----|-||----|||----|-----||||-------  1 [R] COG0699 Predicted GTPases (dynamin-related)
--|----------||-||||||||--||||||||||||----||||||||||||||||||||||--  1 [E] COG0703 Shikimate kinase
|||||||||||||---||||-|---|||||||||||-||-|||||||-||--|--|---|||||--  1 [P] COG0704 Phosphate uptake regulator
-||||-|||||||||-||||-|--|-||||||||||||----|||||-|||||--|--||||||--  1 [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid)
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1 [U] COG0706 Preprotein translocase subunit YidC
||||||-|||||-||-|-----||-------||||||-----|||-|------||-----------  1 [E] COG0710 3-dehydroquinate dehydratase
--|-------------|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0711 F0F1-type ATP synthase, subunit b
-------------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1 [C] COG0712 F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)
|||||||||||||---||||-|---||||||---||||----|||||-||--|--|---|||||--  1 [R] COG0714 MoxR-like ATPases
-||-----||---||--|||||||--|---|--||-||----||||--||||---|---|||||--  1 [P] COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components
-----------------|||||||-|||||||||||||||||||||||||||||||||||||||||  1 [S] COG0718 Uncharacterized protein conserved in bacteria
||||||||||||----||||----------|---|-||----|||||-||||||||||||||||||  1 [H] COG0720 6-pyruvoyl-tetrahydropterin synthase
||||----||-||---||||||||||||||||||||||--||-------|---|||||||||||||  1 [J] COG0721 Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit
|||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||--  1 [P] COG0725 ABC-type molybdate transport system, periplasmic component
--|--|-|-|---|||-|||||||---|||||||||||----|||||-||--|--|||-|||||--  1 [G] COG0726 Predicted xylanase/chitin deacetylase
-|||--|||-------|---|-|||-|------|||||----------|-||-||-|||-------  1 [R] COG0733 Na+-dependent transporters of the SNF family
-------------||-||--|||||||||||||||||||||||||||||----|||||||||||||  1 [I] COG0736 Phosphopantetheinyl transferase (holo-ACP synthase)
-----------------|||||||||||||||||||||-|--||||||||||||||||||||||||  1 [L] COG0742 N6-adenine-specific methylase
|||||||||||||---|-||-|----|||-----||||----|||||-||||--||||||||||--  1 [H] COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A
-------------|--||||||||||||||||||||||----|||||-||||||||||||||||||  1 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains
|||||||||||||---||||||||||||||||||||||----|||||-||||||||||||||||||  1 [M] COG0750 Predicted membrane-associated Zn-dependent proteases 1
-------------||------|----|-------||||----|||||-||||-||||||||||---  1 [P] COG0753 Catalase
--|-----|-|-|---|-||-|----||||----|-||----|||||-||||||||||||||||||  1 [O] COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component
----------------||||||--|||||-|-||||||||--|||||-||||||||||||||||-|  1 [LU] COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake
----------------||||||||||-||-||||||||----|---|-|||||||||||||||||-  1 [S] COG0759 Uncharacterized conserved protein
-------------|||||||||--||----||||||||----||||||||||||||||||||||||  1 [O] COG0760 Parvulin-like peptidyl-prolyl isomerase
-----------------||||-||||||||||||||||----|||||-||||---||||||-||--  1 [S] COG0762 Predicted integral membrane protein
----------------||||||||------||||||||----||||||||||||||||||||||||  1 [I] COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases
|||------|------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase
|--------|------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0773 UDP-N-acetylmuramate-alanine ligase
--|--------------|--|||||||||-||||||||||--||||||||||-|||||||||||--  1 [F] COG0775 Nucleoside phosphorylase
----||----------||||||||||-|||||||||||||||||||||||||||||||||||||||  1 [L] COG0776 Bacterial nucleoid DNA-binding protein
----------------|-||||||--|||-||||||||----|||||-||||||||||||||||--  1 [I] COG0777 Acetyl-CoA carboxylase beta subunit
----------------||||||--|||||-||||||||----|||||-||||||||||||||||||  1 [S] COG0779 Uncharacterized protein conserved in bacteria
----------|-|---||||-------------||-||----|||||-||||||||||||||||||  1 [R] COG0780 Enzyme related to GTP cyclohydrolase I
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0781 Transcription termination factor
-----------------|---|||||||||||||||||||||||||||||||||||||||||||||  1 [K] COG0782 Transcription elongation factor
---|--------------||||--|||----|||||||-|--|||||-|||||--|||||-|-|||  1 [P] COG0783 DNA-binding ferritin-like protein (oxidative damage protectant)
------------------|-|-----|-------|-------|||||-|||--||-||--------  1 [E] COG0786 Na+/glutamate symporter
----||----||----||||||||||----|---||||----|||||-||||||||||||||||||  1 [M] COG0793 Periplasmic protease
|||---|||||||---|---|-||------|---|||-----|||||-||||||||||||||||||  1 [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation
----------------|-||||--||||||||||||||----||||||||||-|||||||||||--  1 [M] COG0796 Glutamate racemase
----------------||||-|||||||||-|||||||----|||||-||||||||||||||||||  1 [S] COG0799 Uncharacterized homolog of plant Iojap protein
-------------||-||||||||--||||||||||||----|||||-||||||||||||||||-|  1 [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase
----------------||||||||||||||||||||||-|--|||||-||||||||||||||||||  1 [R] COG0802 Predicted ATPase or kinase
--------------|---||-|----|||-----|-|||----|||---||----|||-||||---  1 [E] COG0804 Urea amidohydrolase (urease) alpha subunit
--||||--|-|||---|-||-|----||||----||||----|||||-||||||||||||||||||  1 [U] COG0805 Sec-independent protein secretion pathway component TatC
----------------||||||--||||||||||||||----||||||||||||||||||||||||  1 [J] COG0806 RimM protein, required for 16S rRNA processing
----||--|----||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG0807 GTP cyclohydrolase II
----------------||||||---|----||||||||----||||||||||||||||||||||||  1 [J] COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1 [M] COG0812 UDP-N-acetylmuramate dehydrogenase
----------------||||||||--|||||||-||||||||||||||||||||||||||||||||  1 [L] COG0816 Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis)
-----------------|||-|--------||||||||----|||||-|||||||||||||||---  1 [M] COG0818 Diacylglycerol kinase
----||||--|||||----|------|----|-|||||------------||----|||--|----  1 [K] COG0819 Putative transcription activator
----------------||||||--|-|||-|||||||||---||||||||||||||||||||||--  1 [R] COG0820 Predicted Fe-S-cluster redox enzyme
--||----|----|||||-||-||||||||||||||||||||||||||||||-|||||||||||||  1 [C] COG0822 NifU homolog involved in Fe-S cluster formation
----------------|-||||||--|||-||||||||----|||||-||||||||||||||||--  1 [I] COG0825 Acetyl-CoA carboxylase alpha subunit
-|-------------------------|||||||||||------------|-----||-|--|---  1 [L] COG0827 Adenine-specific DNA methylase
----------------|-||--||||----|||||||||-||||||||||||||||||||||||||  1 [J] COG0828 Ribosomal protein S21
--------------|---||-|----|-------|--||----||----||----|||-||||---  1 [O] COG0829 Urease accessory protein UreH
--------------|---||-|----|||-----|--||----|||---||----|||-||||---  1 [O] COG0830 Urease accessory protein UreF
--------------|---||-|----|||-----|-|||----|||---||----|||-||||---  1 [E] COG0831 Urea amidohydrolase (urease) gamma subunit
--------------|---||-|----|||-----|-|||----|||---||----|||--|||---  1 [E] COG0832 Urea amidohydrolase (urease) beta subunit
--|-------------||||||---|----|---|-||----|||||-||||||||||||||||||  1 [V] COG0841 Cation/multidrug efflux pump
|-||||||||||||||-|||-|----||||||||||||----|||||-||-||--|||-|||||--  1 [V] COG0842 ABC-type multidrug transport system, permease component
---|------||||--|-||-|----||||----||||----||||||-|--|--|---|||||||  1 [C] COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1
----------------||||||--|||---|-||||||----|||||-||||||||||||||||||  1 [M] COG0845 Membrane-fusion protein
---------|------||--||--||----||||||||----||||||||||||||||||||||||  1 [D] COG0849 Actin-like ATPase involved in cell division
----------------||||-|----|||||---||||----|||||--|--||||||||--||--  1 [H] COG0853 Aspartate 1-decarboxylase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG0858 Ribosome-binding factor A
----------------|-|||||||||||||---||||----||||||||||||||||||||||--  1 [M] COG0860 N-acetylmuramoyl-L-alanine amidase
------------------||-|----|||-|---||||----||||||||||||||||||||||||  1 [P] COG0861 Membrane protein TerC, possibly involved in tellurium resistance
---|||||---||||-||||-|-----|||----||||----|||||--|--|-||---|||||--  1 [E] COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain
|||||||||||||||-|||||---|--||-||--||-|----|||||-|-------|||-------  1 [C] COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit
|||||||||||||---|||||---|--||-||--||-|----|||||-|------||||---||--  1 [C] COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit
-----------------|---|--------||||||||-|--|||||||-------||-||-|---  1 [G] COG1015 Phosphopentomutase
-------------||-|----|----|-------|-||----|||||-||--|--|--|-|-----  1 [C] COG1017 Hemoglobin-like flavoprotein
---|---------||-----||----|||-----|-||----||||||||--||||---|||||--  1 [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1
---|||--|-|||||-|--|||----|||||-|||-||----|||||-||--|--|---|||||||  1 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase
--|-|||||-|-|---|-----------------|-||-----------|-----|----|-|---  1 [O] COG1030 Membrane-bound serine protease (ClpP class)
-------------||-----------|||-||--||||---------------------||||---  1 [C] COG1038 Pyruvate carboxylase
----------------|-----||-------||||||-||||------------------------  1 [L] COG1039 Ribonuclease HIII
----------------||||||--||-||-||||||||----|||||-||||||||||||||||-|  1 [R] COG1040 Predicted amidophosphoribosyltransferases
--||----------|--|||------||||||||||||----||||||||||-|||||||||||--  1 [E] COG1045 Serine acetyltransferase
--||||----|||||-|----|----||||||--|||-----|||||-||--||||---|||||||  1 [C] COG1048 Aconitase A
||-|||--|||||||-||||||||--||||||--||||----|||||-||||||||||||||||||  1 [C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit
------------------||-|||--|----||||||-----||||||||--|--|---|||||||  1 [R] COG1054 Predicted sulfurtransferase
-------------||-|||||---||||||||||||||||||||||||||--||||||||||||--  1 [H] COG1057 Nicotinic acid mononucleotide adenylyltransferase
---||||||-||||---|||||-----||||-||||||----|||||-|----|||---|||||--  1 [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA
--|-||----|||||---||------||||-||||-||----|||-|--|--|||||||||||---  1 [R] COG1064 Zn-dependent alcohol dehydrogenases
----------------|||||||||-|||-|||-||||----|||||-||||||||||||||||||  1 [O] COG1066 Predicted ATP-dependent serine protease
-------------|--------------------|-||----|||||------------||||---  1 [C] COG1069 Ribulose kinase
--------|---|||--|||----|||||-||-|||||----|||||--|||---|---||||---  1 [G] COG1070 Sugar (pentulose and hexulose) kinases
---|||----||||||--||-|||---||--|||||||-|||-------|-----|---|||||||  1 [C] COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
--------------------|-||||-||-||||||||----||||||||||||||||||||||||  1 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)
|||||||||||||--|||--|----------||||||||-||------------------------  1 [R] COG1078 HD superfamily phosphohydrolases
--------------------||||-||---||||||||-|||||||||||||||||------||--  1 [G] COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)
|||---||||-|-----|||------|||||-|-||||----|||||--|-----|---|||||--  1 [G] COG1082 Sugar phosphate isomerases/epimerases
----||------------||------||||----||||----|||||--||||-------------  1 [R] COG1090 Predicted nucleoside-diphosphate sugar epimerase
-|----||-|--|---||--||||-------||||||-----||||||||||||||---||||---  1 [R] COG1092 Predicted SAM-dependent methyltransferases
|||||-||||-|-||||||-|------||||---|---|||||||-|--|--|---|--------|  1 [L] COG1112 Superfamily I DNA and RNA helicases and helicase subunits
-||-||--||||-----|||||||--|---|--||-||----||||---||||--|---|||||--  1 [P] COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component
||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||--  1 [P] COG1117 ABC-type phosphate transport system, ATPase component
--|----------||------|----||||-|--||||----|||||----|--------------  1 [P] COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA
-||||||||--||----|||||----|---|-|||||||-|||||||-||||---|||||||||--  1 [PH] COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components
|||-|----|-|------|||-----||||----|-------|||||-|------|||-||-|---  1 [R] COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase
--|--|--------------|-||--------|-|--|||--|||||------------||||---  1 [EP] COG1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
----------|-|-------------|||-----|-|-----|||-|--|-----|-----|----  1 [C] COG1140 Nitrate reductase beta subunit
|--|---||-|-|----|||-------||-||||||||----------------------------  1 [C] COG1141 Ferredoxin
----------------||--|||||||||||---||||----||||||||||||||||||||||||  1 [K] COG1158 Transcription termination factor
----------------||||||--||||||||||||||||||||||||||||||||||||||||||  1 [R] COG1159 GTPase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [R] COG1160 Predicted GTPases
--|-------------|||||----||||||||||||||||||||||-||||||||------|---  1 [R] COG1162 Predicted GTPases
---|--------------||------||||-|--|||-----|||||-|-||--------------  1 [H] COG1165 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
---|--------------||------||||-|--|||-----|||||-||||---------|----  1 [HQ] COG1169 Isochorismate synthase
---|||||--|||----|||-|--|-||||||||||||-||||||||-||-||--|---||||---  1 [G] COG1175 ABC-type sugar transport systems, permease components
---|----|-|-|----|-|||--||----||||||--|||||||||-||||-|||---|||||--  1 [E] COG1176 ABC-type spermidine/putrescine transport system, permease component I
---|----|-|-|----|-|||--||----||||||--|||||||||-||||-|||--||||||--  1 [E] COG1177 ABC-type spermidine/putrescine transport system, permease component II
-------------||-----|---------|---|-||----|||||-|||||||||||-------  1 [H] COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
|||-|||||||||---||--|------||-||||||------|||||-||||---|----------  1 [O] COG1180 Pyruvate-formate lyase-activating enzyme
--|-------------||||||||||||||||||||||----|||||-||||||||||||||||||  1 [M] COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes
-------------------|----------||--||||-||||||||--||----|---||-|---  1 [I] COG1182 Acyl carrier protein phosphodiesterase
-------------||-||||||||||||||||||||||----||||||||||||||||||||||||  1 [J] COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)
-------------||-|||||||||||||||||-||||----||||||||||||||||||||||||  1 [J] COG1186 Protein chain release factor B
-----------------|--|-----|---||||||||----|||||-||||-|||||||||||--  1 [J] COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
--|-------||-|||||||||||--|||||||||||||||||||||||||||||||||||-----  1 [J] COG1190 Lysyl-tRNA synthetase (class II)
----------------||||--|||--||-|---||||----|||||-||-----||||-------  1 [K] COG1191 DNA-directed RNA polymerase specialized sigma subunit
|-||--||--------||||||---|----||||||||------------------|||-------  1 [L] COG1193 Mismatch repair ATPase (MutS family)
|--|------|-|-|------||||-||||||||||||----||||||||||||||||||||||--  1 [L] COG1194 A/G-specific DNA glycosylase
----------|-------|||||-|-||||||||||||----|||||-|||||------|||||||  1 [L] COG1195 Recombinational DNA repair ATPase (RecF pathway)
-||||||||----|||||||||--||||||||||||||||||-------|--|||----|||||--  1 [D] COG1196 Chromosome segregation ATPases
-----------------|||||||||||||||||||||----||||||||||||||||||||||||  1 [LK] COG1197 Transcription-repair coupling factor (superfamily II helicase)
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1 [L] COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase
||||||||--|||||||-|||-----|||-||||||||----|||||-||||||||-------|--  1 [KL] COG1199 Rad3-related DNA helicases
----------------||||||--||||||||||||||----|||||-||||||||||||||||||  1 [LK] COG1200 RecG-like helicase
----------------||||||---------|||||||---------------------|||||--  1 [J] COG1206 NAD(FAD)-utilizing enzyme possibly involved in translation
----------------||||||----||||||||||||----||||||||||||||||||||||||  1 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)
|||----|---|----|--||----|||||||||||||--|||||||-||||||||||||||||--  1 [M] COG1210 UDP-glucose pyrophosphorylase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [O] COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone
|-|-||||||||-||||-||------|---|||-||||----|||||--|-----|---|||||-|  1 [M] COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
------------------||||----||||||||||||----||||||||||||||||||||||||  1 [T] COG1217 Predicted membrane GTPase involved in stress response
-------------|--||||||||||||||||||||||----||||||||||||||||||||||||  1 [O] COG1219 ATP-dependent protease Clp, ATPase subunit
----------------||-------|--------||||----|||||||||||--|||||||||||  1 [O] COG1220 ATP-dependent protease HslVU (ClpYQ), ATPase subunit
--||||----|||||-||||-|----|||||---|-||----|||||-||||||||||||||||-|  1 [O] COG1225 Peroxiredoxin
-|------|----|||-|--||--------|||||||-----------|-----------------  1 [C] COG1227 Inorganic pyrophosphatase/exopolyphosphatase
|--||||-|--|-|---|--||-----||-|-|-|-||-------||-||-----|---|||||--  1 [Q] COG1228 Imidazolonepropionase and related amidohydrolases
--||--|-|-|--||-|----|||--||||----||||-------|---------|-------|--  1 [H] COG1232 Protoporphyrinogen oxidase
||||||||||||||||-|||-|||||||||||||||||----|||-|----|---|------||--  1 [R] COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
-|-------|------||--|---------|||-||||----|||||-|-----------------  1 [R] COG1242 Predicted Fe-S oxidoreductase
--|-------|-|-----||-|----|---||-|||||----|||-|-||-----|---|||||--  1 [M] COG1247 Sortase and related acyltransferases
---|||--|-|||-------||-----||||---|-||----|||||-||-----|---|||||||  1 [I] COG1250 3-hydroxyacyl-CoA dehydrogenase
--|-------------|----------||-|---|-||----|||||--|-----|---||-||--  1 [C] COG1251 NAD(P)H-nitrite reductase
--||---------||-|||||||||||||-|||||||-||||||||||||||||||||||||||||  1 [R] COG1253 Hemolysins and related proteins containing CBS domains
-||-|||||-|||----|-|-|---|--|-||||||||----|||||-||-|---|----|-|---  1 [C] COG1254 Acylphosphatases
||||||||||||||||---------|-----|||||------------|-----------------  1 [I] COG1257 Hydroxymethylglutaryl-CoA reductase
|-||--|||--------||||||-|-|---||||||||---------------------||||-||  1 [R] COG1268 Uncharacterized conserved protein
--||||--|-------|-||--||--|||--|--||||----|||||-||||---|--||||||||  1 [C] COG1271 Cytochrome bd-type quinol oxidase, subunit 1
-------------|||----||--|||||-||||||||----|||||-||--|||----|||||--  1 [R] COG1272 Predicted membrane protein, hemolysin III homolog
-|--|-|||----||-----------|||--||||-------|||-|-|-||-|------------  1 [P] COG1275 Tellurite resistance protein and related permeases
--|||||||--||----|||-|--||----|---|||||||--------|-----|----||----  1 [R] COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
--------------------|-----|||-|---|-||----|||||-||-|---|||-|-|---|  1 [R] COG1279 Lysine efflux permease
----------------||||||--------||||||||-|--|||||-||||||||---|||||--  1 [O] COG1281 Disulfide bond chaperones of the HSP33 family
--------------------|---|-|-----||||||-|--|||-|-||--------|||||---  1 [P] COG1283 Na+/phosphate symporter
---------|-------|--|-||-|----||||||||||||------|----------|||----  1 [S] COG1284 Uncharacterized conserved protein
------------------------||-----|||||||----|||||-||||||||||||||||||  1 [R] COG1286 Uncharacterized membrane protein, required for colicin V production
------------------|--|------------|||-----|||||-||||||||--|||||---  1 [S] COG1289 Predicted membrane protein
||||||||||||||||-|||||---|----||||||||------------------|||-------  1 [K] COG1293 Predicted RNA-binding protein homologous to eukaryotic snRNP
--||------------|-||--||--|||--|--||||----|||||-||||---|--||||||||  1 [C] COG1294 Cytochrome bd-type quinol oxidase, subunit 2
--|-------------|-||||||--||||||||||||-|--|||||-||||||||||||||||||  1 [S] COG1295 Predicted membrane protein
--|-----|-----------||----|----|-|||||----|||||-||||-|||||-||||---  1 [E] COG1296 Predicted branched-chain amino acid permease (azaleucine resistance)
|||---||||--|-----||-------||-|---|-||-----------|------------||--  1 [S] COG1300 Uncharacterized membrane protein
--||--||----|---|--||||||||||-|---|-||----|||||-||--|--|--|||-||||  1 [C] COG1301 Na+/H+-dicarboxylate symporters
|||||||||||||||---||-|--||||||-||||||-----|||||-||||-||----|||||||  1 [C] COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
----------------|-|||||||||||||||||||||-|-||||||||||||||||||||||||  1 [U] COG1314 Preprotein translocase subunit SecG
|||||||||||||----|---||||-||||||||||||----|||-|-----|---------|---  1 [K] COG1321 Mn-dependent transcriptional regulator
||-------|-------|--|---------||||||||-|--------------------------  1 [R] COG1323 Predicted nucleotidyltransferase
-----------------||-||||--||||||||||||----|||||-||||||||---|||||--  1 [K] COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains
|||---||-|-------|--|---------||||||------|||||-||||---|----------  1 [F] COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase
-||||||||-------||||||--|-||||||||||||||||-------|--||||---|||||--  1 [S] COG1354 Uncharacterized conserved protein
|||-----||---||-||||-|----||||||--||||-----------|---|||---|||||--  1 [E] COG1364 N-acetylglutamate synthase (N-acetylornithine aminotransferase)
-----------------||||||||--||-|---||||----------||---------||--|--  1 [T] COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
-----------------|------------|||-|||-----|||-|-||||-||-|||||-|---  1 [M] COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
------------------|||||||-||||||||||||||--|||||-||||||||---|||||||  1 [L] COG1381 Recombinational DNA repair protein (RecF pathway)
----------------||||||--||||||||||||||||--||||||||||||||||||||||||  1 [S] COG1385 Uncharacterized protein conserved in bacteria
--|-|||||--------|||||--|-||||||||||||||||-------|--||||---|||||--  1 [K] COG1386 Predicted transcriptional regulator containing the HTH domain
|||-||||||---||-||--||-----||-||--||||----|||||-|-----------|-----  1 [ER] COG1387 Histidinol phosphatase and related hydrolases of the PHP family
|||---|||--|-----|---|||------|---|||-----------||||---|---||-|---  1 [P] COG1392 Phosphate transport regulator (distant homolog of PhoU)
----------------||||-|----||||||||||||----|||||-||||||||----------  1 [R] COG1399 Predicted metal-binding, possibly nucleic acid-binding protein
---|--------------||-|-----||||||-|||-----|||---|---|--|---|||||--  1 [V] COG1403 Restriction endonuclease
|-|---|||||-|||-|-||--||--||||||--|||-----|||||-||||---|---|||||--  1 [R] COG1409 Predicted phosphohydrolases
|-||---------|||--||--||||--------|-||----||-----|------------|---  1 [C] COG1413 FOG: HEAT repeat
-----------------||||-||--||||||||||||||||----------|--|||||||||--  1 [K] COG1420 Transcriptional regulator of heat shock gene
-|--------------|-----------------|-|-----------------------------  1 [H] COG1424 Pimeloyl-CoA synthetase
-----------------|-|--||||-----|||||||----|||||-|||||--|--------||  1 [S] COG1426 Uncharacterized protein conserved in bacteria
----------------||||-|----|---||--||------|||||-||||||||---|||||||  1 [S] COG1434 Uncharacterized conserved protein
---||-----|----|-|---|---|----|||||||||||||||||-|-||-------||-|---  1 [F] COG1435 Thymidine kinase
-------------------------|----||||||||----|||||-|-----------------  1 [G] COG1447 Phosphotransferase system cellobiose-specific component IIA
|-|||||||--||||-||--|-----|---||-|||||----|||||-||-|---|---||||---  1 [C] COG1454 Alcohol dehydrogenase, class IV
-------------------------|----||||||||----|||||-|-----------------  1 [G] COG1455 Phosphotransferase system cellobiose-specific component IIC
----------------||||||||------||||||||----|||||-||||||||------||--  1 [NU] COG1459 Type II secretory pathway, component PulF
-----------------|--||----|||-||||||||||||------------------------  1 [R] COG1461 Predicted kinase related to dihydroxyacetone kinase
----------------||||-|||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG1466 DNA polymerase III, delta subunit
||||||||||--|----|----------------|-||-----------|--||||----------  1 [S] COG1469 Uncharacterized conserved protein
-----------------|--|-----||||||||||||||||------------------------  1 [S] COG1481 Uncharacterized protein conserved in bacteria
--|||||||||||||-||||||--|||||-||||||||||||||||||||-|||||--|||||---  1 [H] COG1488 Nicotinic acid phosphoribosyltransferase
-------------||-||--||----|||-||||||||----|||||-||||-|||----------  1 [J] COG1490 D-Tyr-tRNAtyr deacylase
---------|----------|---|-----||||||||||||----------||||---|||||--  1 [T] COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism
----------------|-||||||-||||||---|-||----|||||-||||||||--||||||||  1 [S] COG1496 Uncharacterized conserved protein
---|||||--|||||---|-||------------|-||-----------|--|------|---|-|  1 [E] COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases
-|----||--------------------------|-|------------------|---|-|----  1 [K] COG1510 Predicted transcriptional regulators
|||-|||||||||---||-|-|----|---|---|-||----|||||--|-----|---|||||--  1 [J] COG1514 2'-5' RNA ligase
|||-||--|-||--------------|||-----||||----|||||-||||---|--||||||--  1 [C] COG1526 Uncharacterized protein required for formate dehydrogenase activity
|-|-----|------|-|--------|||-|---|--||---|||||-|-||----|||-------  1 [P] COG1528 Ferritin-like protein
||||--||||-||-------|---------||||||||----|||||-||||||||----------  1 [J] COG1534 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein
-------------||---||||||--||||||||||||----|||||-||||||||||||||||--  1 [H] COG1539 Dihydroneopterin aldolase
------||------------||----|--|----|-||----|||||-|||--|||--||------  1 [R] COG1540 Uncharacterized proteins, homologs of lactam utilization protein B
----------------||||||-|-|||||||||||||----|||||-|||||--|---|||||||  1 [J] COG1544 Ribosome-associated protein Y (PSrp-1)
---|||----|||---|-||-|------------|-||----------------------------  1 [S] COG1547 Uncharacterized conserved protein
--|--------------|||||----|||-||||||||----|||||-||||||||--|-------  1 [L] COG1555 DNA uptake protein and related DNA-binding proteins
|--|-------|-||---||-|----|||-----|-|---------------||||---|||||--  1 [I] COG1562 Phytoene/squalene synthetase
-------------||--|--||--|-----|||||||-------------------||-||||---  1 [H] COG1564 Thiamine pyrophosphokinase
----------------|-----------------|-|-----|||||-|||--|||---|||||||  1 [V] COG1566 Multidrug resistance efflux pump
-----------------|-|||||--||||||||||||----|||||-||||||||||||||||||  1 [L] COG1570 Exonuclease VII, large subunit
---|-------------||||-----||||-|--|||-----|||||-|-||--------------  1 [H] COG1575 1,4-dihydroxy-2-naphthoate octaprenyltransferase
-----------------|--||--------||||||||||--|||||-||||||||||||||||--  1 [S] COG1576 Uncharacterized conserved protein
||||||--||||-||-|-||||||--|||||---||||----|||||-||-||||||||||||---  1 [H] COG1587 Uroporphyrinogen-III synthase
------------------||-|--||||||||||||||----|||||-||||||||---|||||||  1 [M] COG1589 Cell division septal protein
|-|-----|---------||-|--------|-|-||||----|||||-||-----|---|||||--  1 [C] COG1600 Uncharacterized Fe-S protein
||||||--|||||||-||--||----||||||||||||----||||||||||||||||||||||--  1 [E] COG1605 Chorismate mutase
---|||----|||--------|||--|-------||||----||||||||||-|||||||||||--  1 [I] COG1607 Acyl-CoA hydrolase
--|-||||||||-|--||-|||||--||||-|--|-||----|||||-||-|||||--||||||--  1 [R] COG1611 Predicted Rossmann fold nucleotide-binding protein
---|--------|||-|-||-|----||||----||||-----------|--|--|---|||||||  1 [O] COG1612 Uncharacterized protein required for cytochrome oxidase assembly
-------------||--|--------|---|-|||-||-----||---|--|---|---|------  1 [G] COG1621 Beta-fructosidases (levanase/invertase)
---|----|-||||--|-||-|----||||----||||----||||||-|--|--|---|||||||  1 [C] COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2
-|||--||||------|-||-|||||----||||||||-|||------------------------  1 [S] COG1624 Uncharacterized conserved protein
----------------||--|---------|||-|---------------|||||-|||-----||  1 [S] COG1636 Uncharacterized protein conserved in bacteria
|||||||||||||---------------------||||----------------------------  1 [R] COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold
||||||--|||-|||-|---|------||-|---||||----||||||||--|||----|||||--  1 [H] COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)
---|----|-|-----|-||-|||--||||----|||-----|||||-||||||||||||||||||  1 [O] COG1651 Protein-disulfide isomerase
--||---||------------|--------||||||||----|||||-|||||-------------  1 [K] COG1654 Biotin operon repressor
--------------------||----||||||||||||----|||||-||||||||----------  1 [R] COG1660 Predicted P-loop-containing kinase
|-||||||||--|---------------------|--------||-|-|----------||-|---  1 [R] COG1661 Predicted DNA-binding protein with PD1-like DNA-binding motif
||||--|||-|||----|---|--------||-|||||--------------|----------|--  1 [CP] COG1668 ABC-type Na+ efflux pump, permease component
------------------------||----|---||||----|||||-||---------|||||--  1 [S] COG1671 Uncharacterized protein conserved in bacteria
--|-----|-------|-||------|||||||-||||--------|-||-||||---|-||||||  1 [GM] COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component
--------------------|-||||||||||||||||----|||||-||||||||---|||||||  1 [M] COG1686 D-alanyl-D-alanine carboxypeptidase
----------------|---||---|--------||||||||-----------------|||||--  1 [S] COG1692 Uncharacterized protein conserved in bacteria
--|---|||||||---|||||||||||||-||--||||----|||||-|||||------|||||-|  1 [R] COG1694 Predicted pyrophosphatase
|-|||||||-|||----|-|||----||||||||||||----|||||-|------|------||--  1 [K] COG1695 Predicted transcriptional regulators
-------------||----||---|-----|||||||------------|---||-|-|-|-----  1 [M] COG1696 Predicted membrane protein involved in D-alanine export
---------||-|---||||-|----||||-|||||||----|||||-||-|||||---|||||--  1 [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase
-----------------|-------------||-|||-----|||||-||-----|-----|----  1 [NU] COG1705 Muramidase (flagellum-specific)
-----------------||-||--|-----||||||||||||------------------------  1 [H] COG1713 Predicted HD superfamily hydrolase involved in NAD metabolism
-----------------|-|||----||||||||||||----|||||-||||||||||||||||||  1 [L] COG1722 Exonuclease VII small subunit
----|------|-----|||------|||-|-||||||----------------------------  1 [K] COG1725 Predicted transcriptional regulators
||||||--|--||-----||||----|||-||--||||----|||||-||-||--|--|||-||--  1 [K] COG1733 Predicted transcriptional regulators
--||----|-|-|----|--||||-||-------|-|-----|||||-||||-||----||||---  1 [S] COG1738 Uncharacterized conserved protein
--||---------||--|--||---||---||||||||||--|||-|-||||-|||||||||----  1 [S] COG1739 Uncharacterized conserved protein
--|---------------|--------||-----|-||----|||-|--|-----|---||-||--  1 [S] COG1742 Uncharacterized conserved protein
---------------------|-----||---|||-||------------||-||-----------  1 [S] COG1755 Uncharacterized protein conserved in bacteria
||||||||||||||||||||-|--||||||||||||||----|||||-||||||||||||||||||  1 [K] COG1758 DNA-directed RNA polymerase, subunit K/omega
|||||-|||||||---|-----------------||||----|||||-|-||---|--|||||---  1 [H] COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein
-------------|||||--||--|-----||--||||----------------------------  1 [S] COG1774 Uncharacterized homolog of PSP1
---------------------|----||||-||||-|--||||||||------------|-|----  1 [F] COG1780 Protein involved in ribonucleotide reduction
--||---|-----||--|-|-|----|-------|-||----||||---|--|--|-----|----  1 [P] COG1785 Alkaline phosphatase
----------------|--||-||||----||-|||||----|||||-|||||--||||----|||  1 [M] COG1792 Cell shape-determining protein
|-|-||-------||-|----|------------||||----------------------------  1 [L] COG1796 DNA polymerase IV (family X)
------------------|||-----||||||||||||----------------------------  1 [S] COG1799 Uncharacterized protein conserved in bacteria
--|-|||||-|||---||-|-|------------||||----|||||-||-|---|---||-||--  1 [S] COG1801 Uncharacterized conserved protein
----|------|-----|--||----|||-|||-||||----|||||-||---|||---|||||--  1 [K] COG1802 Transcriptional regulators
---------------------|------------||||----|||||-||--||||---|||||||  1 [S] COG1806 Uncharacterized protein conserved in bacteria
-----------|-----|-|||---||||-||||||||-|--|||||-|||||------|||||--  1 [G] COG1820 N-acetylglucosamine-6-phosphate deacetylase
-------------------------|--------|-|-----|||||-|-||------|-------  1 [R] COG1823 Predicted Na+/dicarboxylate symporter
----------------||||-|||||||||----||||----||||||||||||||||||||||||  1 [J] COG1825 Ribosomal protein L25 (general stress protein Ctc)
--||||--|||||---|-||-|----||||----||||----|||||-||||||||||||||||||  1 [U] COG1826 Sec-independent protein secretion pathway components
||||||||||||----||||-|----||||-|--||||--------------------|-||||--  1 [F] COG1828 Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component
--||------|-|-----|||-----|-----|||--|-----||||-||||||||--|||||---  1 [P] COG1840 ABC-type Fe3+ transport system, periplasmic component
||||||||||||||||||--||--||||||||||||||----||||||||||||||----||||||  1 [J] COG1841 Ribosomal protein L30/L7E
---|------||||--|-||-|----||||----||||----||||||-|--|--|---|||||||  1 [C] COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3
---------------------|---|----||||||||----|||||-|-||-||-|||-------  1 [T] COG1854 LuxS protein involved in autoinducer AI2 synthesis
----------------||--|-||-|||||||||||||----||||||||||||||||||||||||  1 [U] COG1862 Preprotein translocase subunit YajC
------------||------||------------|-||----|||||-||||------|||||---  1 [C] COG1866 Phosphoenolpyruvate carboxykinase (ATP)
-----------------|--------|----|--|-||-|--|||||-|-||--------------  1 [G] COG1869 ABC-type ribose transport system, auxiliary component
||||||-||-||-----|||------|||-----|--|-----------|||---|---||-|---  1 [R] COG1878 Predicted metal-dependent hydrolase
|-|||||||--|-|--|-----||--|||||---|-|-|---|||-|-|--|||||||-||-|--|  1 [R] COG1881 Phospholipid-binding protein
|-------|-----------|---------||||||------|||||-|-||---|----------  1 [C] COG1882 Pyruvate-formate lyase
---|--|||||||||------|------------||------|||||-||-|----||||||||--  1 [R] COG1896 Predicted hydrolases of HD superfamily
|-|--||||--||-----||||----|||||||||-||----|---|--|-|||||--||||||--  1 [M] COG1898 dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes
-|||--|||||||---||-|-------------|||-------||-----------||--------  1 [S] COG1912 Uncharacterized conserved protein
|||----|||-------||--|--------||--||------|||||-||--|--|-||----|--  1 [P] COG1918 Fe2+ transport system protein A
-----------------|||-|--|-----|---|||-----|||||-|---|------|-|||--  1 [M] COG1922 Teichoic acid biosynthesis proteins
-|--------------||------------|---||||----|||||-||||||||----||||--  1 [R] COG1923 Uncharacterized host factor I protein
--------------------|||||||---||||||||||||||||||||||||||---|||||--  1 [G] COG1925 Phosphotransferase system, HPr-related proteins
-----------------||||---------||||||||----------------------------  1 [S] COG1939 Uncharacterized protein conserved in bacteria
|-------|----------|------|----|||||||----||||------|||||||||-||--  1 [R] COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog
----------------|||||||-|-|||||---|||||---||||||||||||||||||||||--  1 [I] COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase
-----------------|--|---------|---||||----|||---------------------  1 [K] COG1954 Glycerol-3-phosphate responsive antiterminator (mRNA-binding)
---|||-------|---|------------||||||||----|||||-||-||||-------||--  1 [T] COG1956 GAF domain-containing protein
|--------|||----||||||---||||||||||-||----||||||||--||||--||||||--  1 [V] COG1968 Uncharacterized bacitracin resistance protein
--|---------------|-||----||||-||||||-----|||||-|||||--|---|||||--  1 [M] COG1970 Large-conductance mechanosensitive channel
-----------------|||-|----||||||--||||----|||||-|||||--|---|||||--  1 [KT] COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases)
--||||-||-||----|-||-|-----||-----||||----|||||-||||---|||||||||--  1 [H] COG1977 Molybdopterin converting factor, small subunit
------------------|||------||||--|||||----|||||-||||---|----|-----  1 [E] COG1982 Arginine/lysine/ornithine decarboxylases
||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||--  1 [H] COG1985 Pyrimidine reductase, riboflavin biosynthesis
||||--||||------||||-|----|||-||||||||----|||||-||||||||--|---||--  1 [NOU] COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
---------------------|--|-|||||---|||||||||||||--|||||||----|--|||  1 [S] COG2001 Uncharacterized protein conserved in bacteria
---|---------||--|-|||--------|---||-|----|||||-||-----|---|||||--  1 [E] COG2008 Threonine aldolase
---|||--|-|-|||------|||---|||----|-||----|||||-||--||||||||||||||  1 [C] COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit
----||-----|-||--|||||--------||-|||||----|||-|-|-||-|||---|||||--  1 [G] COG2017 Galactose mutarotase and related enzymes
|-||---------||------|----||||----||-------------|||||||------||--  1 [E] COG2021 Homoserine acetyltransferase
---|----|--|-||-----||----||||----|-|-----|--||-||-----|---|||||--  1 [I] COG2030 Acyl dehydratase
|--|-------------|--|---|||-----|||--|----------|-----------------  1 [S] COG2035 Predicted membrane protein
------||---|--------||-----||---|||-||-------|---------|----------  1 [O] COG2039 Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)
--------------------|-------------|-||----------||||-||-|||-------  1 [R] COG2056 Predicted permease
------------------||||----|||-||||||||-----------|||---|----------  1 [F] COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase
--------|----|--||-|||----|||-||||||||-----------|--||||||||||-|--  1 [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase
----------------|---------|||-||-|||||-|--|||||-||||---||||-------  1 [O] COG2077 Peroxiredoxin
------------------||----------||||||||----|||||-||||---|---|||-|--  1 [R] COG2081 Predicted flavoproteins
--------|-----------|----|----|---||||----------------------------  1 [M] COG2088 Uncharacterized protein, involved in the regulation of septum location
-------------||---||----------|---|-||----|||-|---|||--|----------  1 [H] COG2091 Phosphopantetheinyl transferase
------------|--|-----|-|-|-||||---|||------------|---------||-|-||  1 [L] COG2094 3-methyladenine DNA glycosylase
------------------||-|--------||--|-||----|||||-|-||--------|-|---  1 [R] COG2103 Predicted sugar phosphate isomerase
--|-||||||||||--||--||-----||---|-||------|||-|--|-----|------|---  1 [R] COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1
--|---||-|-|-|||-----|----||||----|-||----|--|-------------||||---  1 [S] COG2120 Uncharacterized proteins, LmbE homologs
--|-----|----------|-|----|||||--||-||----|||||--|---|||---|||||--  1 [S] COG2128 Uncharacterized conserved protein
---|---------||----|--------------|-|-----|||-|--|-----|------||--  1 [R] COG2130 Putative NADP-dependent oxidoreductases
--|-||||||---||--|--||--|-----||||||||-|--------|-----------------  1 [F] COG2131 Deoxycytidylate deaminase
-----------------|--||--|-||||||||||||----|||||-||||-|||---|------  1 [R] COG2137 Uncharacterized protein conserved in bacteria
||||----||||------||-|----|||-----|-||-----------------|----------  1 [S] COG2138 Uncharacterized conserved protein
--|---|||----||-----------|---||-|||||----|||-|---||----||-|------  1 [H] COG2145 Hydroxyethylthiazole kinase, sugar kinase family
--||||----||--|---||-|----||------|-||----|||||--|--|--|---||-||--  1 [PR] COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases
|||-||||-||||----|---|----||||-|||||||----|---------|--|---|||||--  1 [R] COG2151 Predicted metal-sulfur cluster biosynthetic enzyme
---|--||-|-||-----|-------|||-|---||-----------------------||-||--  1 [R] COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold
---------------------------||-----|-||----|||-|--|------------||--  1 [Q] COG2162 Arylamine N-acetyltransferase
----------------||||||||------||||||||----|||||-|||||--|--|---||--  1 [NU] COG2165 Type II secretory pathway, pseudopilin PulG
---------|-------|--------||||||-|||||----||||||||||||||||||||||||  1 [E] COG2171 Tetrahydrodipicolinate N-succinyltransferase
-----------------|||-|||---||-|---||||----------------------------  1 [T] COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase)
-----------------|--|---------||||||||||||------------------------  1 [L] COG2176 DNA polymerase III, alpha subunit (gram-positive type)
-----------------|||-|---------|||||||----------------------------  1 [R] COG2179 Predicted hydrolase of the HAD superfamily
--------|-|-|-------------|||-----|-|-----|||-|--|-----|-----|----  1 [C] COG2180 Nitrate reductase delta subunit
--------|-|---------------|||-----|-|-----|||-|--|-----|-----|----  1 [C] COG2181 Nitrate reductase gamma subunit
----|-||--|||----|---|---------|||||||----|||||-|----------|------  1 [G] COG2182 Maltose-binding periplasmic proteins/domains
-------------|||---||---|-|---|||||||||---|||||-||||||||---||||---  1 [K] COG2183 Transcriptional accessory protein
----------------||||-|--|-|||||---||||----|||||-||--|--|---|||||--  1 [T] COG2199 FOG: GGDEF domain
|-||----|-----|-||||-|-----||||---|-||----|||---||-----|---|||||--  1 [T] COG2203 FOG: GAF domain
-----------------||||-|||--||-|---||||----------||----------|-|---  1 [TK] COG2208 Serine phosphatase RsbU, regulator of sigma subunit
------------------------------|--|||||-||-|||||||--|--------------  1 [G] COG2213 Phosphotransferase system, mannitol-specific IIBC component
|-||||-||-|||||-|||||||||-|||||||||||||---|||||-||||-|||||||||||--  1 [P] COG2217 Cation transport ATPase
----------------|---------||||----|-||----|||-|--|-----|----||-|--  1 [P] COG2223 Nitrate/nitrite transporter
--|-||----||-||-||||||||--||||----||||----|||||-||-|||||||||||||||  1 [H] COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis
|||-||-----|----||----------------||--------------------|||-------  1 [L] COG2231 Uncharacterized protein related to Endonuclease III
---|||-----|-------------|-||--|||||----|-----|-||----------|-|---  1 [E] COG2235 Arginine deiminase
|----------------||||-|||||||-|---|-||||-----|--||--|||----|||||||  1 [P] COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain)
---||||||||||-----||------||||||-||||-----|---|--|-----|------||--  1 [S] COG2246 Predicted membrane protein
-|-|--||------|--|||||--|||---||||||||-|--|||||-||||-||||||-||-|--  1 [R] COG2252 Permeases
-----------------||||||||||||||||||||||||||||||-||||||||||||||||||  1 [L] COG2255 Holliday junction resolvasome, helicase subunit
-------------||--|--||----|||||||||||||---|||||-||||||||||||||||--  1 [L] COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
---------------------|----|||-|---||||----|||-|--||----|--||-|----  1 [S] COG2258 Uncharacterized protein conserved in bacteria
---|-------|-||----|-|----||||----|-||----|||||-||||-|||---|||||--  1 [S] COG2259 Predicted membrane protein
-------------------|-|----||||-||||-|-----|||||--|-----|---|||||--  1 [S] COG2261 Predicted membrane protein
-|||--||-||||---||||||||--||||||||||||----|||||-||-|||||---|||||--  1 [R] COG2262 GTPases
----------------||||||--------||||||||----|||||-||||||||||||||||--  1 [J] COG2264 Ribosomal protein L11 methylase
------||-----||-||||||||--|||-||||||||----|||||-||||||||--||||||--  1 [J] COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase
--------------|------|----|||-|---|-|---------|--------|-------|--  1 [I] COG2272 Carboxylesterase type B
------------------||||---------|||||||----------------------------  1 [S] COG2302 Uncharacterized conserved protein, contains S4-like domain
||-|-----|---------|-|-----|||----|-------||||---|-----|--||||||--  1 [E] COG2303 Choline dehydrogenase and related flavoproteins
------||-------------|----|||-----|-------------------------------  1 [S] COG2306 Uncharacterized conserved protein
---|--|--|--|---|----|---|-------|||||---------------------||||---  1 [E] COG2309 Leucyl aminopeptidase (aminopeptidase T)
--------------|--|---|------------||------|||--------------||-|---  1 [Q] COG2313 Uncharacterized enzyme involved in pigment biosynthesis
---|------------|----|------------||||----------------------------  1 [S] COG2322 Predicted membrane protein
---|---------------|-|--------||||||||----|||||-||||||||----------  1 [R] COG2333 Predicted hydrolase (metallo-beta-lactamase superfamily)
-------------------|-|-----||-|---||||----|||-------|||----|||---|  1 [T] COG2337 Growth inhibitor
---|--||-----------|-|----|-----||||||----------------------------  1 [S] COG2339 Predicted membrane protein
-----------------|---|--------||||||||----------------------------  1 [R] COG2344 AT-rich DNA-binding protein
------------------|--|----||||----|-||-----------------|--||||||--  1 [R] COG2346 Truncated hemoglobins
----||---------------|----|||-----||------|||||-||--|||||||||-||--  1 [S] COG2353 Uncharacterized conserved protein
--------------|----|-|------------||||----|||||-||||-------|||||--  1 [S] COG2363 Uncharacterized small membrane protein
------------------||||-----||||||||||----------------------||-----  1 [V] COG2367 Beta-lactamase class A
------------------||-|----|-------|--||----|||---||----|||-||||---  1 [O] COG2371 Urease accessory protein UreE
--------------------||----|||||---||||----|---|-||--|-||--||||||--  1 [K] COG2378 Predicted transcriptional regulator
---------------------|----|---|---||||----|||-|--|----------------  1 [P] COG2382 Enterochelin esterase and related enzymes
---------------------|--------|||||||||-||------|-----------------  1 [R] COG2384 Predicted SAM-dependent methyltransferase
--------|---|-------||----|----|--||------|||---||-|-------|||||--  1 [R] COG2388 Predicted acetyltransferase
---------------------|--------||||||||----|||||-|--|---|---||||---  1 [K] COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
---|||---|||-----|---|------------|-------|||||-||--|--|--|||||---  1 [R] COG2391 Predicted transporter component
----||----|||--------|----|||||---|||-----------------------------  1 [R] COG2409 Predicted drug exporters of the RND superfamily
|-||||--|||||||-----------|-------|----------|---|-----|---||||---  1 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog
----||--|-|||---------------------|||-----------------------------  1 [S] COG2427 Uncharacterized conserved protein
|||----||-|-----|-----------------|-||----------------------------  1 [S] COG2445 Uncharacterized conserved protein
-------------------|||----|---||||||||||--|||||-|----|||----------  1 [S] COG2501 Uncharacterized conserved protein
-------------------|------------|-|---|-----------||----||--------  1 [R] COG2503 Predicted secreted acid phosphatase
----------|-|------||-----||-|-||||||-----|||||-||||-|||---|||||--  1 [S] COG2606 Uncharacterized conserved protein
--||||--|--||||-||||||----|---|||-|||||-------|--|||-|||||-|||----  1 [P] COG2608 Copper chaperone
--|-----------------|-----|---|-|-|-||----|||||-||||-|||----------  1 [GE] COG2610 H+/gluconate symporter and related permeases
--------------|---------------||-||||-----||||||-|-----|----------  1 [G] COG2706 3-carboxymuconate cyclase
-----------------|---|--------|---||||----------------------------  1 [R] COG2738 Predicted Zn-dependent protease
--------------------|---------|||||||||||-------------------------  1 [S] COG2739 Uncharacterized protein conserved in bacteria
-------------------|||----||||||||||||||----------------||||||||--  1 [K] COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination
----||-------||--|--|---------||||||--|---------|----||-----|-|---  1 [F] COG2759 Formyltetrahydrofolate synthetase
---|-------|---------|----|---|---||||----------|---|--|---|||||--  1 [Q] COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis
-------------------|------|||-||--||-|----|||-|--|-----|----|-||--  1 [S] COG2764 Uncharacterized protein conserved in bacteria
---------||-------||-|----||||||--||||----|||||-||-----|---|||||--  1 [K] COG2771 DNA-binding HTH domain-containing proteins
----------------||||||||------||||||||----|||||-||||||||--|---||--  1 [NU] COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1 [L] COG2812 DNA polymerase III, gamma/tau subunits
-|----||-|-|-----|---|---------|||||||----||||||||||-------|||||--  1 [J] COG2813 16S RNA G1207 methylase RsmC
--------------------------|||--|--||||----|||||--||||--||||||-|---  1 [G] COG2814 Arabinose efflux permease
-----------------|--||--||||||||||||||----------------------------  1 [S] COG2815 Uncharacterized protein conserved in bacteria
--------------------------||||-|||||-|----|||||-||||-|||---|||||--  1 [L] COG2818 3-methyladenine DNA glycosylase
----------------------------------|||-----||||-------||-----------  1 [P] COG2822 Predicted periplasmic lipoprotein involved in iron transport
---|----------------|----------|||||||----|||||-||---||-----||||--  1 [L] COG2827 Predicted endonuclease containing a URI domain
--------------------||-----------||-------|||-|-||||-||----|||----  1 [S] COG2832 Uncharacterized protein conserved in bacteria
-------------------|-|----|||-----|||-----|||||-||-|-|||------|---  1 [P] COG2837 Predicted iron-dependent peroxidase
-------------------|-|------------|-||---------------||-----------  1 [S] COG2839 Uncharacterized protein conserved in bacteria
-------------------|-|------------||--------|-----|--||-----------  1 [R] COG2842 Uncharacterized ATPase, putative transposase
------------------------------|---|-------|||||---|--|||----|-----  1 [D] COG2846 Regulator of cell morphogenesis and NO signaling
--------------------------|-----|-|-||-----------|--|||---|-------  1 [C] COG2851 H+/citrate symporter
--------|-----------|-----|----|||||------|||||--|||-|||--||||||--  1 [S] COG2855 Predicted membrane protein
-------------------|||---|-||-|--|||||--------------||-|-----|----  1 [E] COG2856 Predicted Zn peptidase
--------------------|---||----|||||||||-||------------------------  1 [J] COG2868 Predicted ribosomal protein
----||-|--|||----|||||||------|-|-||||---------------|------------  1 [E] COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1 [J] COG2890 Methylase of polypeptide chain release factors
-------------------|----|------|-|||||----|||||-|||||--|----------  1 [M] COG2891 Cell shape-determining protein
|||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||--  1 [H] COG2896 Molybdenum cofactor biosynthesis enzyme
--|-----------------------||||-|--|||------------|--|--|---|||||--  1 [S] COG2898 Uncharacterized conserved protein
------------------------||||||-|||||||----||||||||||||||---|||||||  1 [D] COG2919 Septum formation initiator
--------------------|----------||-|--------|--|--||||||----|||||--  1 [K] COG2932 Predicted transcriptional regulator
------------------|--------||--|--||----------------|-------|-||--  1 [R] COG2936 Predicted acyl esterases
--------------------------|-------||||----|||||-||||---|---|||||--  1 [R] COG2962 Predicted permeases
-----|--------------||----|||--|||||-|----|||||-|||----|---|||||--  1 [L] COG2963 Transposase and inactivated derivatives
--------------------|-----|-------|--|----||||--|--|-||--------|--  1 [H] COG2978 Putative p-aminobenzoyl-glutamate transporter
---|||--------------||----------|-|-||-------||-||-----|---|||||--  1 [E] COG2986 Histidine ammonia-lyase
---|||--------------||----------|-|-||-------|--||-----|---|||||--  1 [E] COG2987 Urocanate hydratase
--------------------|---------||||||||----------||----------------  1 [S] COG2996 Uncharacterized protein conserved in bacteria
------------------||------|-------|-------|||||-|--|--------------  1 [G] COG3001 Fructosamine-3-kinase
----------------|-----------------|-|-----------|-----------------  1 [S] COG3002 Uncharacterized protein conserved in bacteria
--------------------|----||----|||||---|--|||||-|-||---------|----  1 [G] COG3010 Putative N-acetylmannosamine-6-phosphate epimerase
------------------||--------------|-||-------|--||--|--|------||--  1 [S] COG3011 Uncharacterized protein conserved in bacteria
-----------------------|------|---||||----|||||-|||||||----|||||||  1 [S] COG3027 Uncharacterized protein conserved in bacteria
--------------------------|-----||||-|-||-|||||-|--|--------------  1 [S] COG3037 Uncharacterized protein conserved in bacteria
--|---------------|------------|--|-|---------|-|----------|-||---  1 [M] COG3049 Penicillin V acylase and related amidases
------------------------------|--|||------|||||-||||-|-|----|-||-|  1 [K] COG3070 Regulator of competence-specific genes
-------------------------------|||||||----|||||-||||--------------  1 [S] COG3091 Uncharacterized protein conserved in bacteria
-------------|||----------|---||--|||-----|||||-|---|||--------|--  1 [E] COG3104 Dipeptide/tripeptide permease
----------------------------------||||----||||||-|--|--|---|-|||--  1 [C] COG3125 Heme/copper-type cytochrome/quinol oxidase, subunit 4
-------------------------------|--||------|||||-||----------|-||--  1 [S] COG3152 Predicted membrane protein
--||------------|--||-----|-----|-||-------|||---|-|-|||||-||-|--|  1 [S] COG3177 Uncharacterized conserved protein
-------------------||-----|-------|-||----|||-|-||---------||-|---  1 [R] COG3180 Putative ammonia monooxygenase
--------------------------|-------|--|----------||---|||---|---|--  1 [S] COG3182 Uncharacterized iron-regulated membrane protein
----||-----|--------------|||-----|-------|||-|--|-----|---||||---  1 [S] COG3189 Uncharacterized conserved protein
--|-----------------|-----------|-||||----------||---||-------||--  1 [S] COG3212 Predicted membrane protein
---|------|--------||-----|||--|--|--|----||||--||---------||-||--  1 [P] COG3221 ABC-type phosphate/phosphonate transport system, periplasmic component
--|----------------|----------|---|-|-----------||----------------  1 [E] COG3227 Zinc metalloprotease (elastase)
-------------------|-|----|---||--||------|||-|--|-|-------|--|---  1 [S] COG3238 Uncharacterized protein conserved in bacteria
--|----------------|-------||--|--||------||||---|-----|----|||---  1 [S] COG3247 Uncharacterized conserved protein
---|||-----||--------|----||||----||||----------------------------  1 [S] COG3253 Uncharacterized conserved protein
--------------------|-------------|-|-----|||||-|-----------|-----  1 [T] COG3275 Putative regulator of cell autolysis
------------------||-|------------|--------------|----------------  1 [S] COG3296 Uncharacterized protein conserved in bacteria
-----------------||||---------|--||-------|||||-||||||||||-|||||||  1 [M] COG3307 Lipid A core - O-antigen ligase and related enzymes
-------------||----|-------|||----|--------------|---------|------  1 [Q] COG3320 Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes
--------------------|-----||-||---||||-----------|----------------  1 [S] COG3323 Uncharacterized protein conserved in bacteria
-------------------------------|||||||||||------------------------  1 [R] COG3331 Penicillin-binding protein-related factor A, putative recombinase
-------------------------------||||||||-||------------------------  1 [K] COG3343 DNA-directed RNA polymerase, delta subunit
--|----------|----|||------||-|---|--|----|--||-||----------|-----  1 [L] COG3344 Retron-type reverse transcriptase
----|------|--|------------||-----|----------||--------|||--------  1 [P] COG3376 High-affinity nickel permease
|---||-----|----------------------|||----------------------||-|---  1 [R] COG3383 Uncharacterized anaerobic dehydrogenase
----||-----|-|-------|------------|-|---------|--|-||--|---|||||--  1 [G] COG3386 Gluconolactonase
---|----------------------||------||||----------------------------  1 [S] COG3402 Uncharacterized conserved protein
---|||-----|-|||---------|-----|||||------------------------------  1 [I] COG3407 Mevalonate pyrophosphate decarboxylase
--------------------||---------|-|||-|----|||-----------------|---  1 [S] COG3412 Uncharacterized protein conserved in bacteria
---|----------------------|||-----||||----------------------------  1 [S] COG3428 Predicted membrane protein
------------------||------|||||||||-------------------------------  1 [R] COG3442 Predicted glutamine amidotransferase
-------------------------------||||-|-----|||-|------------|--|---  1 [R] COG3443 Predicted periplasmic or secreted protein
-----------------|----------------|--|----|---|---------------|---  1 [E] COG3457 Predicted amino acid racemase
-------------------------------|--|-------||||------------|-------  1 [S] COG3477 Predicted periplasmic/secreted protein
-|-------|----------|---------||||||||----------------------|-----  1 [R] COG3481 Predicted HD-superfamily hydrolase
-------------|----|--------------||--------------------|---||-||--  1 [S] COG3542 Uncharacterized conserved protein
---------------------|------------|-||-----------|-----|---|||||--  1 [R] COG3545 Predicted esterase of the alpha/beta hydrolase fold
-------------------------------|||||||||--------------------------  1 [J] COG3557 Uncharacterized domain/protein associated with RNAses G and E
-------------|----------------||--||-------------|---||----|-|----  1 [R] COG3560 Predicted oxidoreductase related to nitroreductase
------------------------------|||-|--------||-----|---|-----------  1 [K] COG3561 Phage anti-repressor protein
---------------|--|-|---------|---|-----------------|------||-|---  1 [G] COG3588 Fructose-1,6-bisphosphate aldolase
-----------|-------------|-----||-||-|----------------------------  1 [S] COG3589 Uncharacterized conserved protein
--|---------------------------|---|||------------|--|---------|---  1 [G] COG3594 Fucose 4-O-acetylase and related acetyltransferases
------||---------|------------|||||||-----------------------------  1 [S] COG3601 Predicted membrane protein
--------------------------|----|--||-|---------------------||-|---  1 [R] COG3607 Predicted lactoylglutathione lyase
-------------------------------||||||||-||------------------------  1 [L] COG3611 Replication initiation/membrane attachment protein
-------------------------------||-|-|-----|||-|--|--|--|-------|--  1 [O] COG3634 Alkyl hydroperoxide reductase, large subunit
---|---------------||-----|----|--|--|-|--||||---|---------||-||--  1 [P] COG3638 ABC-type phosphate/phosphonate transport system, ATPase component
-------------------------------||-|||------|||--------------------  1 [S] COG3645 Uncharacterized phage-encoded protein
----------------------------------||-|-----------|----------|--|--  1 [G] COG3664 Beta-xylosidase
--------------------------------||||------|||-|---------------|---  1 [G] COG3684 Tagatose-1,6-bisphosphate aldolase
------------------||----------|-|-||||----------------------------  1 [R] COG3688 Predicted RNA-binding protein containing a PIN domain
--------------------|---------|---||||-----------|-|-------||-|---  1 [S] COG3708 Uncharacterized protein conserved in bacteria
-------------------------------||-||||----|||---------------------  1 [L] COG3723 Recombinational DNA repair protein (RecE pathway)
-------------------------------||-|||------|||---|------------|---  1 [L] COG3728 Phage terminase, small subunit
--------------------------|----|-|||--------------|--|||---|--|---  1 [S] COG3759 Predicted membrane protein
-------------------------------|||||||||||------------------------  1 [S] COG3763 Uncharacterized protein conserved in bacteria
|--------|----------------|---||||||||----------------------------  1 [M] COG3764 Sortase (surface protein transpeptidase)
------------------------------|-||||-|----|||-|-------------------  1 [G] COG3775 Phosphotransferase system, galactitol-specific IIC component
----|--|--||-----|---|---------|||||||-|--|||||-|-----------------  1 [G] COG3833 ABC-type maltose transport systems, permease component
---------------------|------------|-------|||||--|-|---|---||||---  1 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase
|||||||||||||---||||||--|-||||||||||||-||||||||-||-||--|--|||||---  1 [G] COG3839 ABC-type sugar transport systems, ATPase components
--||----|-|-|----|||||--|||---||||||-||||||||||-||||-|||--||||||--  1 [E] COG3842 ABC-type spermidine/putrescine transport systems, ATPase components
---|--------------||--------------||||----------------------------  1 [T] COG3848 Phosphohistidine swiveling domain
--|------------------|--------|||-||||----------------------------  1 [P] COG3853 Uncharacterized protein involved in tellurite resistance
--------------------|---------||--|||-----------------------------  1 [G] COG3855 Uncharacterized protein conserved in bacteria
------------------------------||||||||----------------------------  1 [L] COG3857 ATP-dependent nuclease, subunit B
--------------------------|---||--||-------------|-----|---||-|---  1 [S] COG3865 Uncharacterized protein conserved in bacteria
----------------------||------|---||||----------------------------  1 [E] COG3869 Arginine kinase
---------------------|--------|---||||----------------------------  1 [S] COG3870 Uncharacterized protein conserved in bacteria
-------------------|-|--------|---|||----------------------|------  1 [R] COG3871 Uncharacterized stress protein (general stress protein 26)
----------------------||------|---||||----------------------------  1 [S] COG3880 Uncharacterized protein with conserved CXXC pairs
--|-----------------|-----|---|---|-------------|-------||--------  1 [L] COG3886 Predicted HKD family nuclease
------------------------------||||||||-|--------------------------  1 [T] COG3887 Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain
-----------------|------------||||||||----------------------------  1 [S] COG3906 Uncharacterized protein conserved in bacteria
------------------------------|---|-|-----------------------------  1 [G] COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation
---------------------------||-||--|-|-----------------------------  1 [R] COG3953 SLT domain proteins
------------------------------|---|-||----------------------------  1 [R] COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain
--|----------||------------|||||--|-----------|-------------------  1 [GHR] COG3961 Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes
-------------------------------||||||-----------------------------  1 [M] COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
-------------------------------|||||||----------------------------  1 [L] COG4098 Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein)
------------------||----------|---||||----------------------------  1 [P] COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
------------------||-|----|---||||||------||||||||||||||---|||||--  1 [J] COG4108 Peptide chain release factor RF-3
------------------------------||||||||----------------------------  1 [K] COG4109 Predicted transcriptional regulator containing CBS domains
-----------------|----------------|-|-----------------------------  1 [R] COG4112 Predicted phosphoesterase (MutT family)
-------------------------------|||||||----------------------------  1 [S] COG4116 Uncharacterized protein conserved in bacteria
--||--------|-|-|-||||----||||||||||||-----------|---||-------|---  1 [R] COG4122 Predicted O-methyltransferase
----------------||--|---------||||||||||--|||||-|-||----||||||||--  1 [R] COG4123 Predicted O-methyltransferase
----------------------------------|-------|||||-||||-------||||---  1 [P] COG4148 ABC-type molybdate transport system, ATPase component
--|---------|---|-||------|||-----||||----|||||-||||---|||||||||--  1 [P] COG4149 ABC-type molybdate transport system, permease component
-||----------------------------|-|||||-------------------------|--  1 [R] COG4152 ABC-type uncharacterized transport system, ATPase component
-----------------|--|-|||||||-||-||||-||--|||||-||||---|||-||||---  1 [E] COG4166 ABC-type oligopeptide transport system, periplasmic component
-------------------------------|||||||----------------------------  1 [S] COG4199 Uncharacterized protein conserved in bacteria
---|---------||---||||----|||--|-|||------|||-|-||||||||||||||----  1 [R] COG4221 Short-chain alcohol dehydrogenase of unknown specificity
------------------||----------|---|-||----------------------------  1 [S] COG4241 Predicted membrane protein
-------------------|-|------------|--------------|----------------  1 [S] COG4270 Predicted membrane protein
-------------|||------||-|--------|-------------------------------  1 [G] COG4284 UDP-glucose pyrophosphorylase
---------------------|------------||-------------------|---||-----  1 [S] COG4292 Predicted membrane protein
-------------------|------|----||||------------------||-----------  1 [P] COG4300 Predicted permease, cadmium resistance protein
------------------||----|---------||------------------------------  1 [S] COG4330 Predicted membrane protein
----------------------------------|--------||---------------|-----  1 [S] COG4333 Uncharacterized protein conserved in bacteria
---|------------------------------||||----------------------------  1 [S] COG4347 Predicted membrane protein
-------------||-----------------|||-------------------------------  1 [S] COG4357 Uncharacterized conserved protein
---------------------|------------|-||----------------------------  1 [PE] COG4362 Nitric oxide synthase, oxygenase domain
---------------------|------------|-||----------------------------  1 [S] COG4365 Uncharacterized protein conserved in bacteria
---------------------|---------|--||------------------------------  1 [S] COG4367 Uncharacterized protein conserved in bacteria
---------------------|---------|-|||-|----------||-----|----------  1 [S] COG4392 Predicted membrane protein
------------------|||-------------||||----------------------------  1 [S] COG4399 Uncharacterized protein conserved in bacteria
----------------------------------|--|-------|---|----------------  1 [S] COG4408 Uncharacterized protein conserved in bacteria
----------------------------------|----------|---|-----------|----  1 [E] COG4413 Urea transporter
-------------------|--------------||||----------------------|-||--  1 [S] COG4430 Uncharacterized protein conserved in bacteria
------------------------------||||||||----------------------------  1 [K] COG4463 Transcriptional repressor of class III stress genes
------------------------------||||||||----------------------------  1 [K] COG4465 Pleiotropic transcriptional repressor
------------------------------||||||||----------------------------  1 [S] COG4466 Uncharacterized protein conserved in bacteria
-------------------------------|||||||----------------------------  1 [S] COG4467 Uncharacterized protein conserved in bacteria
-------------------------------|||||||----------------------------  1 [R] COG4469 Competence protein
-------------------------------|||||||----------------------------  1 [S] COG4470 Uncharacterized protein conserved in bacteria
-------------------------------|||||||----------------------------  1 [S] COG4471 Uncharacterized protein conserved in bacteria
------------------------------||||||-|----------------------------  1 [S] COG4472 Uncharacterized protein conserved in bacteria
-------------------------------|||||||----------------------------  1 [U] COG4473 Predicted ABC-type exoprotein transport system, permease component
-------------------------------|||||||----------------------------  1 [S] COG4474 Uncharacterized protein conserved in bacteria
-------------------------------||||-||----------------------------  1 [S] COG4475 Uncharacterized protein conserved in bacteria
-------------------------------|||||||----------------------------  1 [S] COG4476 Uncharacterized protein conserved in bacteria
-------------------------------|||||||----------------------------  1 [D] COG4477 Negative regulator of septation ring formation
-------------------------------||||||-----------------------------  1 [S] COG4479 Uncharacterized protein conserved in bacteria
------------------------------|-||||-|----------------------------  1 [S] COG4481 Uncharacterized protein conserved in bacteria
-------------------------------||||||-----------------------------  1 [S] COG4483 Uncharacterized protein conserved in bacteria
-------------------------------||||-|-----------------------------  1 [S] COG4485 Predicted membrane protein
--------------------|---------|---|-||----------------------------  1 [R] COG4492 ACT domain-containing protein
-------------------------------|--||||----------------------------  1 [S] COG4493 Uncharacterized protein conserved in bacteria
------------------------------||--|--|----------------------------  1 [S] COG4495 Uncharacterized protein conserved in bacteria
------------------------------|---||||--------------|-------------  1 [S] COG4496 Uncharacterized protein conserved in bacteria
------------------------------|---||||----------------------------  1 [S] COG4499 Predicted membrane protein
------------------------------|---|-|-----------------------------  1 [S] COG4502 Uncharacterized protein conserved in bacteria
------------------------------|---||||----------------------------  1 [S] COG4506 Uncharacterized protein conserved in bacteria
--------------------------------|-||-|----------------------------  1 [S] COG4509 Uncharacterized protein conserved in bacteria
------------------------------|---||-|----------------------------  1 [OTK] COG4512 Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide
--------------------------|||-----|-------|||--------------||||---  1 [S] COG4529 Uncharacterized protein conserved in bacteria
----------------------------------|-------|||||-||||---|----||||||  1 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB
-------------------------------|||||||----------------------------  1 [U] COG4537 Competence protein ComGC
----------------------------------|-|------------|---------|||----  1 [P] COG4548 Nitric oxide reductase activation protein
-------------------------------||-||||----------------------------  1 [S] COG4550 Predicted membrane protein
----------------|--------------||-|||-----|||---------------------  1 [L] COG4570 Holliday junction resolvase
--------------------------|------||-||-------|--|----||---||-|----  1 [P] COG4604 ABC-type enterochelin transport system, ATPase component
--------------------------|------||-||-------|--|----||---||-|----  1 [P] COG4605 ABC-type enterochelin transport system, permease component
--------------------------|------||-||-------|--|----||---||-|----  1 [P] COG4606 ABC-type enterochelin transport system, permease component
--------------------------|------||-||-------|--|----||---||-|----  1 [P] COG4607 ABC-type enterochelin transport system, periplasmic component
----------------------------------|-------|||-|--------|----------  1 [R] COG4619 ABC-type uncharacterized transport system, ATPase component
------------------------------||--||------|||-----------------|---  1 [R] COG4626 Phage terminase-like protein, large subunit
------------------------------|---|-|-----------------------------  1 [S] COG4640 Predicted membrane protein
---------------------|--------||-|||||--|-||||||||||---|----------  1 [G] COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain
---||-----|-|-------|-------------||-|----|||-|--------|----|||---  1 [I] COG4670 Acyl CoA:acetate/3-ketoacid CoA transferase
-------------------------------|||||------------------------------  1 [S] COG4699 Uncharacterized protein conserved in bacteria
-------------------------------|--|--|----------------------------  1 [S] COG4707 Uncharacterized protein conserved in bacteria
------------------------------|-||||---------------------------|--  1 [S] COG4709 Predicted membrane protein
-------------------------------||-||------------------------------  1 [S] COG4716 Myosin-crossreactive antigen
--|-------------------------------|||-----------------------|-----  1 [S] COG4717 Uncharacterized conserved protein
------||----------------------|||||-------------------------------  1 [S] COG4720 Predicted membrane protein
--------------------------|------||-|-----------------------------  1 [S] COG4721 Predicted membrane protein
----------|-|--------------------||-------------------------------  1 [S] COG4732 Predicted membrane protein
--------------------|-----------||||||----------------------------  1 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
-------------------------------|||||||----------------------------  1 [S] COG4758 Predicted membrane protein
-------------------------------|||||||----------------------------  1 [R] COG4768 Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain
-------------------------------|||||------------------------------  1 [C] COG4781 Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase
----------------------------------||------|||-|-------------------  1 [S] COG4808 Uncharacterized protein conserved in bacteria
-------------------------------|--||------------------------------  1 [R] COG4814 Uncharacterized protein with an alpha/beta hydrolase fold
--------------------------|-------||------------------------------  1 [S] COG4815 Uncharacterized protein conserved in bacteria
----------------------------------||||----------------------------  1 [S] COG4836 Predicted membrane protein
----------------------------------||||----------------------------  1 [S] COG4837 Uncharacterized protein conserved in bacteria
----------------------------------||||----------------------------  1 [S] COG4838 Uncharacterized protein conserved in bacteria
-------------------------------|||||||----------------------------  1 [D] COG4839 Protein required for the initiation of cell division
----------------------------------||||----------------------------  1 [S] COG4840 Uncharacterized protein conserved in bacteria
----------------------------------||||----------------------------  1 [S] COG4841 Uncharacterized protein conserved in bacteria
--------------------------|||||---||||----------------------------  1 [S] COG4842 Uncharacterized protein conserved in bacteria
----------------------------------||||----------------------------  1 [S] COG4843 Uncharacterized protein conserved in bacteria
----------------------------------||||----------------------------  1 [S] COG4844 Uncharacterized protein conserved in bacteria
----------------------------------||||----------------------------  1 [O] COG4846 Membrane protein involved in cytochrome C biogenesis
----------------------------------||||----------------------------  1 [S] COG4848 Uncharacterized protein conserved in bacteria
----------------------------------||||----------------------------  1 [R] COG4851 Protein involved in sex pheromone biosynthesis
----------------------------------||||----------------------------  1 [S] COG4853 Uncharacterized protein conserved in bacteria
------------------------------|-||||||----------------------------  1 [S] COG4856 Uncharacterized protein conserved in bacteria
-------------------------------|||||||----------------------------  1 [OTN] COG4862 Negative regulator of genetic competence, sporulation and motility
----------------------------------||||----------------------------  1 [S] COG4863 Uncharacterized protein conserved in bacteria
----------------------------------||||----------------------------  1 [S] COG4864 Uncharacterized protein conserved in bacteria
----------------------------------|||-----------------------------  1 [S] COG4873 Uncharacterized protein conserved in bacteria
----------------------------------|||-----------------------------  1 [S] COG4876 Uncharacterized protein conserved in bacteria
----------------------------------|||-----------------------------  1 [S] COG4896 Uncharacterized protein conserved in bacteria
----------------------------------|||-----------------------------  1 [S] COG4897 Uncharacterized protein conserved in bacteria
----------------------------------|||-----------------------------  1 [K] COG4903 Genetic competence transcription factor
-------------------------------|--|||-----------------------------  1 [R] COG4915 5-bromo-4-chloroindolyl phosphate hydrolysis protein
--------------------|-------------|-------------------------|-----  1 [R] COG4927 Predicted choloylglycine hydrolase
-------------------------------|||||||------------------|||-------  1 [U] COG4940 Competence protein ComGF
---|||--||-||----|||||----||||||--||||----|||||--|-----|---|||||--  1 [MR] COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily
----------------------------------||||----------------------------  1 [S] COG4955 Uncharacterized protein conserved in bacteria
------------------||-|--------||--||||----------------------------  1 [R] COG4956 Integral membrane protein (PIN domain superfamily)
------------------||----------|---||||----------------------------  1 [R] COG4980 Gas vesicle protein
-------------------------------|--||||----|||||-|-||-------|-|-|--  1 [CO] COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components
--------------------|-----|||--||-||||----|||||-|-||-------|-|-|--  1 [CO] COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components
------------------------------|--|||||----|||||-|----------|--|---  1 [R] COG4989 Predicted oxidoreductase
-------------------------------|--|||-----------------------------  1 [S] COG4990 Uncharacterized protein conserved in bacteria
---------------------|---------|||||||----------------------------  1 [T] COG5002 Signal transduction histidine kinase
----------|-|-------------|||-----|-|-----|||-|--|-----|-----|----  1 [C] COG5013 Nitrate reductase alpha subunit
-------------||-------------------|-------------------------------  1 [H] COG5146 Pantothenate kinase, acetyl-CoA regulated
--|------------------|---------|--|||-----------------------------  1 [S] COG5280 Phage-related minor tail protein
----------------||-------|--------||||----|||||||||||--|||||||||||  1 [O] COG5405 ATP-dependent protease HslVU (ClpYQ), peptidase subunit
--------------------------------|-||-|----------------------------  1 [S] COG5412 Phage-related protein
----------------------------------||||----------------------------  1 [S] COG5417 Uncharacterized small protein
----------------------------------||||----------------------------  1 [S] COG5444 Uncharacterized conserved protein
-------------------------------|||||||----------------------------  1 [S] COG5503 Uncharacterized conserved small protein
---------------------|------------|-||----------------------------  1 [O] COG5504 Predicted Zn-dependent protease
------------------------------|---||-----------------|------------  1 [L] COG5527 Protein involved in initiation of plasmid replication
--------------------------------|-||------------------------------  1 [S] COG5546 Small integral membrane protein
-------------------------------||||-------------------------------  1 [S] COG5547 Small integral membrane protein
---------------------------||--|--||------|||-|-------------------  1 [R] COG5562 Phage envelope protein
------------------------------|---|-||----------------------------  1 [M] COG5577 Spore coat protein
----------------------------------||||----------------------------  1 [S] COG5582 Uncharacterized conserved protein
----------------------------------||||----------------------------  1 [S] COG5584 Predicted small secreted protein
----------------------------------|||-----------------------------  1 [M] COG5632 N-acetylmuramoyl-L-alanine amidase
||-|||-|-||-|||-|-|||------|||-----|-|----------------------------  0 [P] COG0003 Oxyanion-translocating ATPase
|||||||||||||||-||||-------||||-||-|||----|--||--|--|------||-|---  0 [F] COG0005 Purine nucleoside phosphorylase
--|----------||-||||-|--|-||||||||-|||----|||||-||||||||--||||||--  0 [E] COG0014 Gamma-glutamyl phosphate reductase
-|----||---|------||------|||-------|-----|||||-||-|--------------  0 [F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)
---|--||---|----|-|||------||||----|||----|||||-||--||||---||-||--  0 [H] COG0029 Aspartate oxidase
-|||||||||-||||-|-||||----|||-||||---|----|||||-|-||-|||---|-|||--  0 [P] COG0038 Chloride channel protein EriC
|||-||||||||||--|-||-|||------------||----|||||-||-|-|||||||||-|||  0 [H] COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases
-||---||--||-|--|-||||||--|||-||||--||----|||||-||||-------||-|---  0 [G] COG0058 Glucan phosphorylase
||||--||||--||----||-------||--|---|-|----||||--|-|---------|||---  0 [E] COG0076 Glutamate decarboxylase and related PLP-dependent proteins
|-||--|||---||||--|--|-----||-|-----||-|--|||||-||--|--|---|||||--  0 [L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase
-||--|--|||||||-|-||-------|-------|-|------------------||-|||||--  0 [EQ] COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit
------|---|--||--|--|---|-|||-||-|--||----|||||-|-||--------------  0 [G] COG0153 Galactokinase
--------|-||-||-|-||-|----|||-|-----||----||||||||--||||---|||||--  0 [P] COG0155 Sulfite reductase, beta subunit (hemoprotein)
||||--||||||-|--|||||-----|||||-||-|||----|||||-||||||||||-||-||--  0 [H] COG0157 Nicotinate-nucleotide pyrophosphorylase
|||-||||||||||--|-||-|||------------||----|||||-||-|-|||||||||-|||  0 [H] COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase
-||||-||-||||||---||||----|||-|-----||----||||||||--||||---|||||--  0 [EH] COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes
|||-|||||||||||-|||||---------------|------------|--|-------|-|---  0 [J] COG0182 Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family
-|||--|||-|||-----||-|---------------|--||||||||||||||||---|||||--  0 [HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)
|-||||||-|-||||||-||||||--|||||----|-|||||||||||||||||||||||||||||  0 [C] COG0221 Inorganic pyrophosphatase
------------------|--|----||||-----|------|||||-||||---|---|||||||  0 [F] COG0232 dGTP triphosphohydrolase
||||-||||||-|||-||-||------||||-||-|||-||-|||||-|||||--|||--||||||  0 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
||-||||||||||---|-||-|----|||-------||----|||||-||||---|||||||||--  0 [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing
----------------|||||||||-|||||----|||--||||||||||||||||||||||||--  0 [I] COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
||||||--|||||---|-||||----||||-|----||----|||||-||||-||||||||||---  0 [C] COG0247 Fe-S oxidoreductase
--|--------|-|--||||||----|||||------|----|||||-||||||||||||||||||  0 [FP] COG0248 Exopolyphosphatase
--|----------||-||||-|--|-||||||||-|||----|||||-||||||||--||||||--  0 [E] COG0263 Glutamate 5-kinase
||----||-||||-|---||------|---|-||--||||--|||-|-|-|-||||||--|-||--  0 [L] COG0270 Site-specific DNA methylase
--||||--|-|||||-|-||||----|||||-----||----|||||-||||||||||||||||--  0 [C] COG0277 FAD/FMN-containing dehydrogenases
|--|------||-||---||-|----|||||-||--||----|||||-||||||||||||||||--  0 [P] COG0288 Carbonic anhydrase
--|--------|-|--|-||||||--|||----|--|-----|||||-||||---|---||-|---  0 [G] COG0296 1,4-alpha-glucan branching enzyme
-|----||--||--|-||||||||------||-|--||----|||||-||||---|---||-|---  0 [G] COG0297 Glycogen synthase
----------||-||-|-||||----||||||||-|||----|||||-|||||--|||||||||||  0 [H] COG0302 GTP cyclohydrolase I
||||----||--------||----------|----|----------|---|----------|----  0 [P] COG0310 ABC-type Co2+ transport system, permease component
|||-|||||||||---||||-|-----||-|------|----||||||||||||||---|||||--  0 [R] COG0312 Predicted Zn-dependent proteases and their inactivated homologs
-------------|||--|||---|||||||----|||----|||||||||||--||||-|-|-||  0 [O] COG0326 Molecular chaperone, HSP90 family
|||||||||||||||-||||||--||||||||||---|-|--||||||||||||||||||||||||  0 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs
-|--|||-----------|||---|-----|----|-|----|||||-|-||||--||-------|  0 [L] COG0338 Site-specific DNA methylase
|||-----||------||||-|----|||-||---||-----|||||-||||||||---|||||--  0 [E] COG0347 Nitrogen regulatory protein PII
|||||||||||-||||----------||||||---|||----|||||-||--|-------|-|---  0 [E] COG0367 Asparagine synthase (glutamine-hydrolyzing)
|||||||||||||-----||||----|||-|----|-|----|||-|-||-----|---||||---  0 [H] COG0368 Cobalamin-5-phosphate synthase
|||||||||||||-|--|||----------||||-|||----|||||-------------|-----  0 [C] COG0371 Glycerol dehydrogenase and related enzymes
--||----|----|----|--------||--------|----|||||-|---|--|---||-||--  0 [P] COG0376 Catalase (peroxidase I)
||||--||||||----|||||-----|||||----|||----|||||-||--||||||-||-||--  0 [H] COG0379 Quinolinate synthase
|||||||||||||||-|-||-|||--|||||------|----|||||-||-|||||||||||||||  0 [H] COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases
-----||----|-||--|||-------||--|||-|-|----|-----------------------  0 [G] COG0383 Alpha-mannosidase
--||---------||---||||----|||-|----|||----|||-|-||-|---|---|||||--  0 [R] COG0384 Predicted epimerase, PhzC/PhzF homolog
-------------||---||-|----||||------|-----|||||------------||-|---  0 [P] COG0387 Ca2+/H+ antiporter
|||||||||--|-----|||-------|||-|---|-|----|||-|-|--|-----------|--  0 [S] COG0393 Uncharacterized conserved protein
---|||||--|||----|||-|--|-||||||||-|||-||||||||-||-||--|---||||---  0 [G] COG0395 ABC-type sugar transport system, permease component
-------------||---||------|----------|----|||-|-||--|--|---||--|--  0 [S] COG0397 Uncharacterized conserved protein
||-----|-||-----||||----|-|||-|--|--|-----|||||-||-|-||||||-||||--  0 [M] COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis
|||||||||||||||-||||-|----|---|--|---|----|||||--||||--|||||||||--  0 [FR] COG0402 Cytosine deaminase and related metal-dependent hydrolases
-|------|-|||----|||||----|------|---|----|||||--|-----|--|||||---  0 [E] COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
--|-|------|-||-|-||-------|||------|-----|||||--|-----|---||-||--  0 [Q] COG0412 Dienelactone hydrolase and related enzymes
-|--|||||||||||-||---|----|---|--|--||----||||||-|--||||||----|---  0 [E] COG0421 Spermidine synthase
||||---|||||----||||||----|||||-----||----|||||-||--||||--|||-||--  0 [H] COG0422 Thiamine biosynthesis protein ThiC
--|---||-----||-||||||||--|||||-----||----|||||-||-|||||||||||||||  0 [D] COG0424 Nucleotide-binding protein implicated in inhibition of septum formation
||||--||--||||||||-|-|---||||------|------|||-|--|---|||--|-|-----  0 [P] COG0428 Predicted divalent heavy-metal cations transporter
|||---|||||||-|-||||-|-----||-|-----||----|||-|-||---------||-----  0 [S] COG0432 Uncharacterized conserved protein
|||||||||||||---||||-|-----||---|----|----||||---|-|---|---|||||--  0 [R] COG0433 Predicted ATPase
-----------------|||||||--||||||-|--||----|||||-|-||-------||-|---  0 [G] COG0448 ADP-glucose pyrophosphorylase
||-|--||||------||-|----||-||||-----||----------||-----||||-------  0 [D] COG0455 ATPases involved in chromosome partitioning
||||||||||||||||--||-|----||||------||-----------|-----|--|||-|---  0 [O] COG0464 ATPases of the AAA+ class
--|----------||-||--||||||----|-----||||||||||||||||||||||||||||||  0 [O] COG0466 ATP-dependent Lon protease, bacterial type
|||-|--------||||-|||-----||||||||-||||||||||||--|----------|||---  0 [P] COG0474 Cation transport ATPase
--------|-------|----|-----||||||---|-----------------------------  0 [P] COG0490 Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels
|||||||||||||||||-||||----|||||-||-|||----||||||||||||||||||||||--  0 [O] COG0501 Zn-dependent protease with chaperone function
-------||---|||-|-|--|-----||-|-----||----||||||||--|--|--|-||||--  0 [P] COG0529 Adenylylsulfate kinase and related kinases
||||||||||||-||-|||-----||-----------|----|||||-|--|--------|-----  0 [P] COG0530 Ca2+/Na+ antiporter
|||-||||||-|-||-||--|---|-|||-||-|-|||----|||||-||---|||---|----||  0 [HC] COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases
--||-||||--|||||-|||||||--|||-||||-|||--|||||||-|||||-------|-----  0 [KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family
||||||||||||------||-|-----||-|------|----|||||-||||||||---|||||--  0 [O] COG0555 ABC-type sulfate transport system, permease component
-|------|-|||----|||||----|------|---|----|||||--|-----|--|||||---  0 [E] COG0559 Branched-chain amino acid ABC-type transport system, permease components
|||||||||||||---||||||--|-|||||--|-||-----|||||-||--||||||||||||||  0 [G] COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase
|||-||--||-|-||--||--|----|||--|---|||-------|---||-||||---|||||--  0 [S] COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit
|||||||||||||---|-||------||||------||----||||||||||||||--|----|--  0 [H] COG0611 Thiamine monophosphate kinase
||||----|--||---||||-|--------|------|----|||||-||||-|||----------  0 [R] COG0613 Predicted metal-dependent phosphoesterases (PHP family)
|||||||||-|-|---|||||||||-||||-----|||----||||||||||||||||||||||||  0 [OU] COG0616 Periplasmic serine proteases (ClpP class)
-|||||||||||||||-|||||--------||-|-|||----||||||||||||||--|||-||--  0 [T] COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases
--||--|||--------|||-|--||----|----|||----|||||-||--|--||||||-||--  0 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases
--|----------||||-||--||--||||-|---|||----|||-|-||-|---|||-||-|---  0 [P] COG0659 Sulfate permease and related transporters (MFS superfamily)
|-||||-----|-||---||-------||||------|----|||||-||-|||||---|||||||  0 [R] COG0661 Predicted unusual protein kinase
|||---||||------|||||------||-------||----|||||-||--||||||-|||||--  0 [G] COG0662 Mannose-6-phosphate isomerase
|||-||||-|-|----|-||-|----|||-|-----||----|||-|-||--||||--||||||||  0 [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily
--|||||||-|||||-|-||-|||-|||||||||-|||----|||||-||||||||||||||||--  0 [E] COG0665 Glycine/D-amino acid oxidases (deaminating)
-|-|----|-|||----|||||----|------|---|----|||||--|-----|--|||||---  0 [E] COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
|||-----||---|-------|----||||-------|----|||||-||||---|---||-|---  0 [H] COG0684 Demethylmenaquinone methyltransferase
||||----||---||-----||||---||||-----||----|||||-|||||||||||||||-||  0 [I] COG0688 Phosphatidylserine decarboxylase
|---|||||||||||||--|||----||||-----|||----|||||-||||||||---|||||||  0 [J] COG0689 RNase PH
------------------|-----------|-----||----|||-|-||-----|----------  0 [S] COG0700 Uncharacterized membrane protein
|||-----||------||||-------||-|-||-|||----|||-------------|-------  0 [R] COG0701 Predicted permeases
|-|-||--|--|-|||--||||--|||||-||||-||-----|||||-||||||||||||||||||  0 [L] COG0708 Exonuclease III
|||-----||---||---|||---|-----||||-||-----|||||||||||--||||-------  0 [C] COG0716 Flavodoxins
|||||||||||||---|-||--||--|||||------|----||||||-|||||||||||||||||  0 [F] COG0717 Deoxycytidine deaminase
--||||----|||||-|-||-|----|||||-----||----------||--||||||||||||||  0 [C] COG0723 Rieske Fe-S protein
-------------|----------------------|-----|||-|---|-|||-|||--|-|--  0 [G] COG0738 Fucose permease
----------------||||----||----||||-|||----||||||||||||||||||||||||  0 [M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)
----------------|||||||||-|||||----|||----|||||||||||||||||||--|--  0 [I] COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase
----------------|||||-||-------|||-|||----||||||||||||||||||||||||  0 [J] COG0751 Glycyl-tRNA synthetase, beta subunit
----------------|||||-||-------|||-|||----||||||||||||||||||||||||  0 [J] COG0752 Glycyl-tRNA synthetase, alpha subunit
-------------||||---|-|||-||||||||-||-----||||||-|||||||||-|||||||  0 [F] COG0756 dUTPase
-----------------|||||----|||||-----||-------|-||||||--|||||||||--  0 [E] COG0757 3-dehydroquinate dehydratase II
----------------|||||||||-|||||-----||----||||||||||||||||||||||--  0 [IM] COG0761 Penicillin tolerance protein
|-||--|||----|||-|||-|--||-||-|----|||----|||||-|||||--|||||||||--  0 [T] COG0784 FOG: CheY-like receiver
|-|---|||-|-|---||||||--|-||||--||--||------------||----||-||||---  0 [O] COG0785 Cytochrome c biogenesis protein
---|------------|-||-|----|||-------||----|||-|-|||||--|||||||-|--  0 [F] COG0788 Formyltetrahydrofolate hydrolase
------------------||-|||--||||||---|||----|||||-||||||||||||||||--  0 [M] COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
|-|---|-|----|---|||------|||-|----||--------------|--|----|------  0 [P] COG0798 Arsenite efflux pump ACR3 and related permeases
-----------------|||----|-----||||--||----|||||-||||||||||-|||||--  0 [G] COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase
----------------|||||||||-|||||-----||----||||||||||||||||||||||--  0 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis
--||--|||--------|||----||----|----|||----|||||-||--|--||||||-||--  0 [NT] COG0835 Chemotaxis signal transduction protein
--||--|||--------|||-|--||----|----|||----|||||-||--|--||||||-||--  0 [NT] COG0840 Methyl-accepting chemotaxis protein
----------------||||||--------|----|||----||||||||-|||||||-||||---  0 [D] COG0850 Septum formation inhibitor
--|---------------||-|-----||||------|----|||||-||--||||||||||||--  0 [P] COG0855 Polyphosphate kinase
-|-||||----------|-|||----------|--|-|----|||||-|-|-||-|||-|||||--  0 [L] COG0863 DNA modification methylase
||||--|||||||-----------------|----|||----|||-|---------||---|-|--  0 [K] COG0864 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain
|||-----||-----------|---|----|----|||----|||--------------||||---  0 [F] COG1001 Adenine deaminase
-|||||----|----------|---||---|-----|-|----||-|---|---|-|||----|--  0 [V] COG1002 Type II restriction enzyme, methylase subunits
-|||---||--|----|-||------|||---|---||----|||||-||-||--|--||||||||  0 [M] COG1004 Predicted UDP-glucose 6-dehydrogenase
||||||--||||------|||------||-|----|----------|--|-----|---||||---  0 [H] COG1010 Precorrin-3B methylase
---------------------------||-------|-----|||||-||-----------|----  0 [Q] COG1021 Peptide arylation enzymes
---|------------|----|-----||--|----||---------------------|--|---  0 [G] COG1023 Predicted 6-phosphogluconate dehydrogenase
----||-----------|-|------|---|-----||----|||||-||||-||-||||-|----  0 [E] COG1027 Aspartate ammonia-lyase
|||-|||||||||----|||||-----||-||-----|----|||-|-||------------|---  0 [C] COG1032 Fe-S oxidoreductase
-|||--||||-------|------||-----------|-----------|--------|-------  0 [R] COG1033 Predicted exporters of the RND superfamily
|||---|||||||---|-||-|----||||||-|-|||-------|--||-----|---|||||-|  0 [F] COG1051 ADP-ribose pyrophosphatase
||||||--|||-|---||||||||---||||------|----|||||-|-------|||-------  0 [HR] COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes
-----------|-||---||------||||-------|----|||||--||--|||---|||||--  0 [C] COG1062 Zn-dependent alcohol dehydrogenases, class III
||||||||||-------|------|-----|-----||----|||||-||||--------------  0 [O] COG1067 Predicted ATP-dependent protease
-----|-------||-----------||||-|||-|||----|||||-|-||-------||||---  0 [H] COG1072 Panthothenate kinase
--||---||---||||-|-|||||--|||-|||--|||----|||||-||-||--|---|||||--  0 [R] COG1073 Hydrolases of the alpha/beta superfamily
|---||--||------||-||-||||----|----|||----|||||-|||||--||||----|||  0 [D] COG1077 Actin-like ATPase involved in cell morphogenesis
---|--|||-|-|----|-|-|--||----||||-||-||||-------|-----|---||||---  0 [R] COG1079 Uncharacterized ABC-type transport system, permease component
|------------||-|-||||----|---||-|-|||--|||||||-||||-|||||||||||--  0 [M] COG1087 UDP-glucose 4-epimerase
|-|--||||--||-|---||||----|||||||---||----|||||--|||||||---||-||--  0 [M] COG1088 dTDP-D-glucose 4,6-dehydratase
|-||-||||--||---|-||||----|||||||---||----|---|--|--||||---||-||||  0 [M] COG1091 dTDP-4-dehydrorhamnose reductase
------------------||-------||--------|----|||||-||--||||||||||||--  0 [P] COG1118 ABC-type sulfate/molybdate transport systems, ATPase component
-----------------|--|---|||----|----||-|--|||||-||||---|---|||||--  0 [G] COG1129 ABC-type sugar transport system, ATPase component
|--|||--|-|||-------||---------|----||----|||------|-||||||-------  0 [C] COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain
|||-|||||||||----|||||--------|-----|-----|||||-|||||||||||||-|---  0 [C] COG1145 Ferredoxin
----------------|||||||||-||||||---|||----||||||||||||||||||||||--  0 [HI] COG1154 Deoxyxylulose-5-phosphate synthase
----------------||----||||----|----|||----||||||||-----|||||||||--  0 [NU] COG1157 Flagellar biosynthesis/type III secretory pathway ATPase
--------------------||----||||||-|-|||----|||||---|----|----------  0 [E] COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
-----------------|--|-----|--|-|----||----|||||-||||---|---|||||--  0 [G] COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components
---|--||--|-|-----||||--|-|------|---|----|||||-||||-|||--|||||---  0 [P] COG1178 ABC-type Fe3+ transport system, permease component
||||----||---||-----|-||-|-||||-----||-----------|--|||||||||||-||  0 [I] COG1183 Phosphatidylserine synthase
--|-----|-------|||||----|||||||||-|||||----------------||||||||||  0 [J] COG1189 Predicted rRNA methylase
||-|-|||-|||----|-||-||||||||||----|||--|||||||-||--||||||||||||||  0 [D] COG1192 ATPases involved in chromosome partitioning
|||---|||-|||---||--|-----------|----|----|||||----|--------------  0 [R] COG1203 Predicted helicases
|||---||||||-||----|-|----|||-------||-----||---------------|-----  0 [R] COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
|||||||||||||||||-||-|----|||||-----||-------||--|--||||--||||||--  0 [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)
|-|||||||--||----|||-|----|||||||---||----|||||--|--||||---||-||--  0 [M] COG1209 dTDP-glucose pyrophosphorylase
-----------------|||----------|----||-----|||||-||-----|----------  0 [KT] COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
||||||||||-|||--||||-|----|||-||---|||||--|||||-|||-||||||||||||||  0 [P] COG1226 Kef-type K+ transport systems, predicted NAD-binding component
------------------||-|----|||-------|------------|-----|------||--  0 [E] COG1231 Monoamine oxidase
--||------------|----|-----|||------||----||||||||-|-|||----------  0 [E] COG1246 N-acetylglutamate synthase and related acetyltransferases
----------------||------||----|----|||----||||||||-----|||||||||--  0 [N] COG1256 Flagellar hook-associated protein
--|-----------|---||--||---||-------||----------||-|||||---|||||--  0 [S] COG1262 Uncharacterized conserved protein
|||---||-||-|---|---|-----------|--|||----|||||-||||-||||||-----||  0 [I] COG1267 Phosphatidylglycerophosphatase A and related proteins
|||||||||||||-----||||-----||-|----|-|--------|-||-----|---||||---  0 [H] COG1270 Cobalamin biosynthesis protein CobD/CbiB
--------|------------------||-------||-----------|---------||-|---  0 [S] COG1273 Uncharacterized conserved protein
----------------|----|-------------|||----|||||--------|----|-|---  0 [P] COG1276 Putative copper export protein
|-|-||--|||||----||--|----|---------||----|||||-|||||--|--||||||--  0 [E] COG1280 Putative threonine efflux protein
----------------|-||||--|--||-||-|-|||----|||||--|||---|---|||----  0 [S] COG1285 Uncharacterized membrane protein
---|||----||||--|-||-|----||||------||----------||--||||||||||||||  0 [C] COG1290 Cytochrome b subunit of the bc complex
----------------||------||----|----|||----|||||-||-----|||||||||--  0 [N] COG1291 Flagellar motor component
----------------||----||||----|----|||----||||||||-----|||||||||--  0 [NU] COG1298 Flagellar biosynthesis pathway, component FlhA
|-|---||||||----||||-|-----||||----|||-----------||||--|---||-||--  0 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases
----||-----------|------------||----||----|||||---|--------||||---  0 [G] COG1312 D-mannonate dehydratase
-----------------|------||----|------|----------|-----------------  0 [L] COG1315 Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain
-----------------|----||||----|-----||----||||||||-----||||---|---  0 [NU] COG1317 Flagellar biosynthesis/type III secretory pathway protein
----------|||--------|--||-||-------||----|||----|-----|---||-|---  0 [C] COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs
---------------------|--||||||------||---------------------|||||||  0 [K] COG1329 Transcriptional regulators, similar to M. xanthus CarD
|-||||--|-|||---|--|-|||---||-|-----|------------------------||---  0 [O] COG1331 Highly conserved protein containing a thioredoxin domain
----------------|-||------||||------||---------------|||----------  0 [O] COG1333 ResB protein required for cytochrome c biosynthesis
----------------||------------|-----||----------||------|||-------  0 [N] COG1334 Uncharacterized flagellar protein FlaG
|-------||-|----||-------------------|----------------------------  0 [L] COG1336 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily)
----------------||----||||----|----|||----||||||||-----|||||||||--  0 [NU] COG1338 Flagellar biosynthesis pathway, component FliP
|||--|--||||-----|-||------||---|----|----------------------------  0 [L] COG1343 Uncharacterized protein predicted to be involved in DNA repair
----------------||------||----|----|||----|||||-||-----|||||||||--  0 [N] COG1344 Flagellin and related hook-associated proteins
----------------||------||----|----|||----|||||-||-----||||-------  0 [N] COG1345 Flagellar capping protein
--||--|||--------|-|----||----|----|||----|||||-||-----|--|||-||--  0 [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins
|||--||-||||----||---------||--------|----------------------------  0 [R] COG1353 Predicted hydrolase of the HD superfamily (permuted catalytic motifs)
--||--------------||-|--|-|||-||---|||----|||||--|-|-------||-||||  0 [S] COG1357 Uncharacterized low-complexity proteins
--||--------------|-||----|||-||-|-||-----|||||-||-|-|||---||-||--  0 [S] COG1359 Uncharacterized conserved protein
----------------||------||----|----|||----|||||-||-----|||||||||--  0 [N] COG1360 Flagellar motor protein
--------|-------||-------------------|----------------------------  0 [L] COG1367 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily)
-|--||||-|--||--|-||-|-----|||------|-----------------------------  0 [L] COG1372 Intein/homing endonuclease
-||-|-||--||-----|--|------||----|-|--------------|-----|||---|--|  0 [R] COG1373 Predicted ATPase (AAA+ superfamily)
-----------------|||------|||||-----||----|||-|-||---|||---||||---  0 [S] COG1376 Uncharacterized protein conserved in bacteria
----------------||----||||----|----|||----||||||||-----|||||||||--  0 [NU] COG1377 Flagellar biosynthesis pathway, component FlhB
|||||||||||||--------|--------------|-----------------------------  0 [K] COG1378 Predicted transcriptional regulators
|||---||-|--------------------------||----------------------------  0 [S] COG1379 Uncharacterized conserved protein
|-|---|---||----|-|--|-----------|--|-----|--|----------|||-------  0 [V] COG1401 GTPase subunit of restriction endonuclease
||-|-----||||----|||-------||------|-|---------------------|||||--  0 [R] COG1402 Uncharacterized protein, putative amidase
--||----|-|-|||||-||||----|||||-||--||||------|-||--||||--|||-|---  0 [O] COG1404 Subtilisin-like serine proteases
-----------------|------||----|------|----------|-----------------  0 [N] COG1406 Predicted inhibitor of MCP methylation, homolog of CheC
|-|-------|-----|--|-|||--||||||---|||----|------------||||-|-|---  0 [R] COG1408 Predicted phosphohydrolases
-----------------|||-|----|||||------|----|||||-|||-|--|---|||||--  0 [E] COG1410 Methionine synthase I, cobalamin-binding domain
---|------------||---|----|||-------||----|||||-||||---|--||||||--  0 [K] COG1414 Transcriptional regulator
----------------||------||----|----|||----------||-----||||-------  0 [N] COG1419 Flagellar GTP-binding protein
----||--|-|-|---|----|||-------------|------------------|||-------  0 [R] COG1427 Predicted periplasmic solute-binding protein
-------------------------|----||||-|||----|||||-|-----------------  0 [G] COG1440 Phosphotransferase system cellobiose-specific component IIB
---------------------------------|--|-----|||-|---||----||--|---||  0 [M] COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases
----||||---|-|---------------------|||----|||-|--|-|-||-----------  0 [F] COG1457 Purine-cytosine permease and related proteins
|||---|||-|||---||-||-----------|----|----------------------------  0 [L] COG1468 RecB family exonuclease
--|---|||----------------------------|----------------------------  0 [S] COG1470 Predicted membrane protein
-----------|--|--|||-|---|||||||---|||----|||||-||||||||---|||||||  0 [G] COG1472 Beta-glucosidase-related glycosidases
--|-------------||--|||||-----||||-|------|||||-||||||||----||||--  0 [H] COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis
-|||--|----------|-||-----|---|----|--||---|||--|--|--|-|||-------  0 [S] COG1479 Uncharacterized conserved protein
-----------------||||--||-----|----|||----------------------------  0 [R] COG1480 Predicted membrane-associated HD superfamily hydrolase
-----------------|------------|----|||----|||||-|----------||-|---  0 [G] COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
|---||--|-|||---||||----------|------|----|||||-||||-------|||-|--  0 [R] COG1489 DNA-binding protein, stimulates sugar fermentation
||||||--||-|------||||-----||-|----|-|--------|-||-----|---|||||--  0 [H] COG1492 Cobyric acid synthase
--|---------------||||----|||||-----||----|||-|-|-||---------|||--  0 [G] COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins
---------------------|||------------||----|||||-||||||||||||||||||  0 [O] COG1495 Disulfide bond formation protein DsbB
----||----||-||--|-|----------||-|-|-|----|||||--------|---|---|--  0 [G] COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases
----------------|-----||||----|----|||----|||||-||--||||||||||||--  0 [K] COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
-||-------------||--||--|-----------||----|||||-|-|||------||-||--  0 [E] COG1509 Lysine 2,3-aminomutase
-----------------|||----|------|----||----|||----|-|---|-----|||--  0 [R] COG1512 Beta-propeller domains of methanol dehydrogenase type
---||||||||||-|-||-|-|--------|-----|-----|||||-----|-------------  0 [L] COG1515 Deoxyinosine 3'endonuclease (endonuclease V)
----------------||------||----|----|||----|||||-||-----||||-------  0 [NUO] COG1516 Flagellin-specific chaperone FliS
|||-|||-|||||---||-||------||---|--|-|----|||||----|--|---|-------  0 [L] COG1518 Uncharacterized protein predicted to be involved in DNA repair
||||--|||--------|---|---|-|||------|-----|||||-||--|--|-------|||  0 [S] COG1520 FOG: WD40-like repeat
----------------||||||--||-||||----|||-|---------|--|||||||----|--  0 [K] COG1521 Putative transcriptional regulator, homolog of Bvg accessory factor
|||||||||||||--------|----|||-|-----||----|||||-||||-|||---|||||--  0 [K] COG1522 Transcriptional regulators
--|--------|-----||-||||--|||-|-||--||-|--|||||-||||---|---||-|---  0 [G] COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases
----|||||--|-|||-|-|------|---|----|-|-----------|--|-----|-|-||--  0 [R] COG1524 Uncharacterized proteins of the AP superfamily
----------|||---|----|--|--||-------||----|||----|-----|---||-||--  0 [C] COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs
---|--||-||||---|||||-||--|||||----|-|----||||||||||||||---|||||||  0 [J] COG1530 Ribonucleases G and E
-||-|-|||||||----||-|------||-|-----||-----------|-----|---|||||-|  0 [L] COG1533 DNA repair photolyase
-----------------|------------------|-----|||-|-||-----------|----  0 [Q] COG1535 Isochorismate hydrolase
----------------||----||||----|----|||----||||||||-----|||||||||--  0 [N] COG1536 Flagellar motor switch protein
|-|-----|--|-------|||---------------|----|--|--|---|--|----------  0 [H] COG1541 Coenzyme F390 synthetase
------||----------||----|--||||------|----------------------------  0 [S] COG1543 Uncharacterized conserved protein
---|------------||||||----|||||-||-||||||||||||-||--||||||||||||--  0 [R] COG1546 Uncharacterized protein (competence- and mitomycin-induced)
-----------------|---|-----||||----|||----------------------------  0 [S] COG1550 Uncharacterized protein conserved in bacteria
-----------------|------||----|-----||----|||||||||||---|||-------  0 [T] COG1551 Carbon storage regulator (could also regulate swarming and quorum sensing)
------|------|-----|-------|||||---||--|--|||--------||-----------  0 [G] COG1554 Trehalose and maltose hydrolases (possible phosphorylases)
---|----|-----------||---------|----||----|||------|-||||||-------  0 [S] COG1556 Uncharacterized conserved protein
----------------||------||----|----|||----||||||||-----|||||||||--  0 [N] COG1558 Flagellar basal body rod protein
----------------|---||--||||||||||-|||----|||||-||||||||||||||||||  0 [R] COG1559 Predicted periplasmic solute-binding protein
----------------||--|----|----|----|||----|||||-||||||||---|||||--  0 [S] COG1561 Uncharacterized stress-induced protein
--||||||----|---||--||-----||------|||--------|--|-----|---|||||--  0 [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold
----------------||------||----|-----||----|||||-||-----||||-------  0 [N] COG1580 Flagellar basal body-associated protein
-----------------|------||----|-----||----------------------------  0 [N] COG1582 Uncharacterized protein, possibly involved in motility
-|--|||||-|||---||------------|-----||----||||||-|--|--|----------  0 [E] COG1586 S-adenosylmethionine decarboxylase
|||----|||-|-----|-||---------|-----|---------------------|-------  0 [C] COG1592 Rubrerythrin
-----------------|--|---|-|----------|----|--||-||||-------||--|--  0 [G] COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
--------||-|----||-------------------|----------------------------  0 [L] COG1604 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily)
-------------|---|--------|||-|----|||----------||--||||--|||||---  0 [S] COG1610 Uncharacterized conserved protein
------------------||-------|||-------|----|||||--|--||||---|||||--  0 [P] COG1613 ABC-type sulfate transport system, periplasmic component
----||------------||||--|-----||-|-|||-|--|||-|-||---|||--------||  0 [V] COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF
-----------------|--|-----|||-|-----||----------------------------  0 [R] COG1623 Predicted nucleic-acid-binding protein (contains the HHH domain)
|-|---||---|----||------------|-----||---------------------||||---  0 [S] COG1633 Uncharacterized conserved protein
-----------------||-|---|-|---------||----|--||-||||---|---||-||--  0 [G] COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
------------------||-|--------------|-----||||---------|-----|----  0 [S] COG1649 Uncharacterized protein conserved in bacteria
-------------------|-|--||---------||-----|||-|-||-|||||---|||||--  0 [S] COG1652 Uncharacterized protein containing LysM domain
---|||||--|||----|||-|--|-||||||||-|||----|||||-||-||--|---||||---  0 [G] COG1653 ABC-type sugar transport system, periplasmic component
--|------|---||---||----------------|-----------------------------  0 [I] COG1657 Squalene cyclase
----------------------||||----|-----|--------|--||--|--||||----|--  0 [M] COG1664 Integral membrane protein CcmA involved in cell shape determination
-------------------|-------||-------||----|||||-||||---|--|-------  0 [S] COG1666 Uncharacterized protein conserved in bacteria
----------------||------||----|----|||----||||||||-----|||||||||--  0 [NU] COG1677 Flagellar hook-basal body protein
|-|-------------||--|---------|----|||--------|-||-----|---||-|---  0 [S] COG1683 Uncharacterized conserved protein
----------------||------||----|----|||----||||||||-----|||||||||--  0 [NU] COG1684 Flagellar biosynthesis pathway, component FliR
--|-----------------|-----|---------|-------------||----||--------  0 [E] COG1687 Predicted branched-chain amino acid permeases (azaleucine resistance)
|||||||||||||--|||-|-|----|||-|------|----|||-|--|-----|----------  0 [S] COG1690 Uncharacterized conserved protein
-----------------|------||----|-----||------------------|||-------  0 [S] COG1699 Uncharacterized protein conserved in bacteria
---||||||--||--------|----||||-------|----|||----------|-------|--  0 [E] COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family
-||--------------|--|---|-------||-|--||---|||---|-|---|---|||||--  0 [S] COG1704 Uncharacterized conserved protein
|--------|--------||-------||||----|||----------|||--|||||||||||||  0 [S] COG1714 Predicted membrane protein/domain
----------||-||---||-|||--|||||------|--------------|-------------  0 [T] COG1716 FOG: FHA domain
--|||||||-|-|---||||-|---|-|||-----|||----------||-----|---|||||--  0 [R] COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
-----------------|------||----|-----||----------------------------  0 [S] COG1728 Uncharacterized protein conserved in bacteria
----------------|-----||||----|-----||----||||||||||||||--||||||||  0 [T] COG1734 DnaK suppressor protein
-----------|---------|-----||------|-|-||-|---|------------|--|---  0 [R] COG1735 Predicted metal-dependent hydrolase with the TIM-barrel fold
---|--|||-|-|----|-|-|--||----||||-|||||||-------|-----|---||||---  0 [R] COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein
----|||-|-|-|||---||-|-----------|---|----------|--|----|||||||---  0 [E] COG1748 Saccharopine dehydrogenase and related proteins
----------------|-------||----|----|------||||||||-----|||||||||--  0 [N] COG1749 Flagellar hook protein FlgE
-------------||||||-|---|--|||-|----||----|||-|-||--||||---|||||||  0 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily
-||-||||-|-||---||---|----|||-|----|-|--|||||||-||---|||---||-||--  0 [O] COG1765 Predicted redox protein, regulator of disulfide bond formation
----------------||------||----|----|||----||||||||-----|||||||||--  0 [NU] COG1766 Flagellar biosynthesis/type III secretory pathway lipoprotein
--||--|||--------|------|-----|----|||----------|-------|||-------  0 [NT] COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
-------------------------|------|--||-------------|---------------  0 [R] COG1783 Phage terminase large subunit
-----------------||--|---------------|------------------||--------  0 [V] COG1787 Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes
--------|--|--------||----|||-|-|---||----|------||----|||-|||||-|  0 [I] COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit
-------------||-|--|----------------|------------|--|-------------  0 [S] COG1791 Uncharacterized conserved protein, contains double-stranded beta-helix domain
|||||||||||||||||----------||-------||----------|||--||---|||-||--  0 [L] COG1793 ATP-dependent DNA ligase
------|||----------------------|----|-----|||||----|---|--|||-||--  0 [M] COG1794 Aspartate racemase
||||||--||||------||||-----||-|----|-|--------|--|-----|---||||---  0 [H] COG1797 Cobyrinic acid a,c-diamide synthase
-----------------||------|----|----|||----|||||-|-||---|---|||----  0 [G] COG1803 Methylglyoxal synthase
------|||-------|-|||---------|-----|-----|||||--|--||||---|||||--  0 [M] COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
||-------|----------------|---------|-----------------------------  0 [S] COG1809 Uncharacterized conserved protein
--------|--------|--||--------|----|||----|||-|-------------------  0 [R] COG1811 Uncharacterized membrane protein, possible Na+ channel or pump
----------------||------||----|----|||----||||||||-----|||||||||--  0 [N] COG1815 Flagellar basal body protein
|||------|---|----|--|-----||||-----|------||||-||------------|---  0 [GC] COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
|--------|-------|--|---------|-||-|||----------------------------  0 [R] COG1827 Predicted small molecule binding protein (contains 3H domain)
---|||||--|||---||---|---------|||-|||----|||||--------|--|||-|---  0 [R] COG1832 Predicted CoA-binding protein
--|---------|-----||-------||-|-----||-----------|----------|-|---  0 [E] COG1834 N-Dimethylarginine dimethylaminohydrolase
|||||||||-|-------||-----------------|----------------------------  0 [S] COG1836 Predicted membrane protein
----------------||||||||||-|||||||-|||------------------|||-------  0 [R] COG1837 Predicted RNA-binding protein (contains KH domain)
|||---|||||-----||------------|------|----|||||-||--||||-----||---  0 [C] COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain
--|-------------|-||-|----|||-|----|||----|||||-||------------||--  0 [KT] COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
----------------||------||----|----|||----||||||||-----|||||||||--  0 [N] COG1843 Flagellar hook capping protein
-----------------|||||--||-|||||||-|||----------------------------  0 [R] COG1847 Predicted RNA-binding protein
-||---|||---------||----------------|-----------------------|-|---  0 [G] COG1850 Ribulose 1,5-bisphosphate carboxylase, large subunit
-|------------------|---|-----|-----|--------------------------|--  0 [M] COG1861 Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog
-||||||||||||-----------------------||----------------------------  0 [S] COG1865 Uncharacterized conserved protein
----------------||------||----|----|||----||||||||-----||||||||---  0 [N] COG1868 Flagellar motor switch protein
--||--|||--------|-------|----|-----||----------||-----|---||--|--  0 [NT] COG1871 Chemotaxis protein; stimulates methylation of MCP proteins
||||||||||--------------------|-----||----------------------------  0 [S] COG1873 Uncharacterized conserved protein
------||---------|------------|--|--||-------|------|-------|--|--  0 [G] COG1874 Beta-galactosidase
-----------------|----||--||||------||----------||--|--|----------  0 [T] COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH
------------------||----||----||||-|||-------|--|-|||-------------  0 [M] COG1876 D-alanyl-D-alanine carboxypeptidase
--|--------------|--|---|-|--|||----||----|||||-||||---|---|||||--  0 [G] COG1879 ABC-type sugar transport system, periplasmic component
---||||||--||--------|----||||-------|----|||----------|---|||||--  0 [I] COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit
----------------||----||||----|----|||----||||||||-----|||||||||--  0 [NU] COG1886 Flagellar motor switch/type III secretory pathway protein
-----------------|------------||-|--||----|||||-|---------||||----  0 [E] COG1897 Homoserine trans-succinylase
|||-||--||||------|||---------|----|----------|--|-----|---|-|----  0 [H] COG1903 Cobalamin biosynthesis protein CbiD
-----------------|--------|---||----||----|||||-------------||||--  0 [G] COG1904 Glucuronate isomerase
-|||||--|-|-------------------|-----|------------------|----------  0 [P] COG1910 Periplasmic molybdate-binding protein/domain
||||||||--||----|||||-----||--|||--|||-------||--|-----||||||||---  0 [S] COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain
|||-----||------||--|---------||---|------|||---------------------  0 [I] COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain)
||||----|----------|---------------|----------|-------------------  0 [P] COG1930 ABC-type cobalt transport system, periplasmic component
--|----------||----|------||||-|---|||----||||||||||||||--||||||--  0 [HE] COG1932 Phosphoserine aminotransferase
--||||-----|-----|-|||------|-|--|---|----|||||-|||--|||||----||--  0 [L] COG1943 Transposase and inactivated derivatives
------------------||-|----||||-----|||-----------------|----------  0 [S] COG1950 Predicted membrane protein
|||---|||||-----||------------|------|----|||||-||--||||-----||---  0 [C] COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain
-----------||||---------------------|-----|||||--|-----|----||||--  0 [FH] COG1953 Cytosine/uracil/thiamine/allantoin permeases
-----------------|||-|--||-----|---|||----------------------------  0 [S] COG1963 Uncharacterized protein conserved in bacteria
--|----|--|-|---|---|-----|||-||----||----|||||-||||-||||||-------  0 [T] COG1966 Carbon starvation protein, predicted membrane protein
|-|-----------------|-----|---|-----||----|||||--|--|||---|-------  0 [S] COG1971 Predicted membrane protein
----------|||--------|-----||-------||----|||----|-----|---|||||--  0 [O] COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family
----------------||------------|-----|-----------------------------  0 [S] COG1978 Uncharacterized protein conserved in bacteria
-----------------|-||---------|----|||----|||||-|--|--------------  0 [C] COG1979 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family
--|---||---------|--------|---||||-|||----|||||-|-----------------  0 [KT] COG1983 Putative stress-responsive transcriptional regulator
||--||--|||||------------------------|----|||||-|-----------------  0 [S] COG1986 Uncharacterized conserved protein
----------------||------||----|----|||----||||||||-----|||||||||--  0 [NU] COG1987 Flagellar biosynthesis pathway, component FliQ
||||||-||||||---||||-|-----||-|----|||----------|----|||||--|-||--  0 [R] COG1994 Zn-dependent proteases
----------------|-|||----------------|----|||||-||-|||||||||||||--  0 [H] COG1995 Pyridoxal phosphate biosynthesis protein
---|------|-|||-|----|--------------||----------||--||||--||||||||  0 [R] COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems
---|--|||-|||-----||-------||-|----|||----|||--------------||-|---  0 [K] COG2002 Regulators of stationary/sporulation gene expression
--|-----|---------||-|----||||------||----------||---|||||||||||--  0 [C] COG2010 Cytochrome c, mono- and diheme variants
----------------|-||||----|||||-----||----|||||-||--||||--||||||--  0 [H] COG2022 Uncharacterized enzyme of thiazole biosynthesis
---|||--|-|||||--|--||----|||||-----||----|||-|--|--||||---|||||--  0 [C] COG2025 Electron transfer flavoprotein, alpha subunit
--|---------------||-|----||||------|-----|||||-||||||||----------  0 [M] COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)
--------|---|-------|-----|-----|----|----|------||-----||--------  0 [I] COG2031 Short chain fatty acids transporter
--|----------||-|----|-----||||-----|-----|||||-|--|-|||----||-|--  0 [P] COG2032 Cu/Zn superoxide dismutase
|||||||||||||-----||||----|||||------|----|||-|-||-----|---|||||--  0 [H] COG2038 NaMN:DMB phosphoribosyltransferase
-------------||---|--------||||-----|-----|----------------|--|---  0 [E] COG2040 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)
--||||--|-|||---|--|-|----|||-------|-----|||||--|-|---|--||||||--  0 [R] COG2041 Sulfite oxidase and related enzymes
||--||---|-------|||-|--------|-----|------------------|----------  0 [HR] COG2045 Phosphosulfolactate phosphohydrolase and related enzymes
-------||-|||||-|-||-|--------------||--------------------|-------  0 [P] COG2046 ATP sulfurylase (sulfate adenylyltransferase)
-----------------|||----------|-----||----------------------------  0 [S] COG2052 Uncharacterized protein conserved in bacteria
||----||-|----------------|---|-----|-----|||-|--|||-------||||---  0 [C] COG2055 Malate/L-lactate dehydrogenases
-----------|--------||----|||-|-|---||----|------||----|||-|||||-|  0 [I] COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit
-|---------------|||||---||---------||-|--------||-----|---||-||--  0 [P] COG2059 Chromate transport protein ChrA
------------------|||-----|---------||----|||||-||-----|---|||||--  0 [E] COG2066 Glutaminase
|--------||||--------|-----||-------||----|||----------|---||-||--  0 [R] COG2068 Uncharacterized MobA-related protein
--------------|-----|------|||||||-|------|||----|--------||||||||  0 [R] COG2071 Predicted glutamine amidotransferases
-------------||---|--|----||||------||-----------|-----|---||-||--  0 [P] COG2072 Predicted flavoprotein involved in K+ transport
||-|||--||||------|||---------|----|----------|--|-----|---||||---  0 [H] COG2073 Cobalamin biosynthesis protein CbiG
--||---------------|-|-----|||||---|||----|||||-||---||---||||||--  0 [P] COG2076 Membrane transporters of cations and cationic drugs
|---||----||||------------|||-------||----|||-|--|-----|---||-|---  0 [R] COG2079 Uncharacterized protein involved in propionate catabolism
----------|||--------|--||-||-------||----|||----|-----|---||-||--  0 [C] COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs
||||||--||||------|||------||-|----|----------|--|-----|---||||---  0 [H] COG2082 Precorrin isomerase
|-|-||----|||---|-||-|-----||-||---|||----|||||-||||-|||-|-|||||--  0 [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
---|||--|-|||||--|--||----|||||-----||----|||-|--|--||||---|||||--  0 [C] COG2086 Electron transfer flavoprotein, beta subunit
------------------||||----|||-|----|-|----|||-|-||-----|---||||---  0 [H] COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase
-||-----------------|---|-----|-----|----------------|--|||----|--  0 [M] COG2089 Sialic acid synthase
-||-|||||||||---|--|-||||-----------|-----||||||||-|||||--||||||--  0 [U] COG2095 Multiple antibiotic transporter
---||||||-|||-------||----||||-----|||--------|--|-----|---|||||--  0 [S] COG2096 Uncharacterized conserved protein
||----------------|||------||-|----|----------|--|-----|---||||---  0 [H] COG2099 Precorrin-6x reductase
|-|||||||-------|-||||----|||||-----||----||--|-||--||||--||-|||--  0 [H] COG2104 Sulfur transfer protein involved in thiamine biosynthesis
-||---|---||------||-|--------------||----|||||-||-----|----------  0 [S] COG2105 Uncharacterized conserved protein
----||--|-|||---|----|||-------------|------------------|||-------  0 [R] COG2107 Predicted periplasmic solute-binding protein
--|----------------------|-----||--||-----|||||--|-----|---||||---  0 [E] COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components
-----------------|-------------|----||----|||||---|--------||||---  0 [G] COG2115 Xylose isomerase
---|---------||---||-|----|||||-----||-----------|--|--|--||||||--  0 [Q] COG2124 Cytochrome P450
---|------|--||-|--|------|||-------||----|||||--|||||||--||||||--  0 [Q] COG2132 Putative multicopper oxidases
----------|-------||-|---|-|||-------|----|||-|--|--|--|---||-||--  0 [G] COG2133 Glucose/sorbosone dehydrogenases
---|---------|-----|------||||------|-----|||-|--|---------||||---  0 [S] COG2135 Uncharacterized conserved protein
--|---|||---------|-----------------|---------|--------|---||-|---  0 [GR] COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzymes
--|---||----|---||-----------------|---------|--------------------  0 [G] COG2152 Predicted glycosylase
--------------|---|-------|||--|-----|----|||-|-||-----------|----  0 [R] COG2153 Predicted acyltransferase
--|-------------------||------|-----||----------------------|-|-|-  0 [S] COG2155 Uncharacterized conserved protein
-----------------|------------|-----||----|||||-------------|-----  0 [G] COG2160 L-arabinose isomerase
||----||-|||||||--------------|------|----------------------------  0 [J] COG2163 Ribosomal protein L14E/L6E/L27E
---------------------------||--|---|||----|||||-||-----|---|||||-|  0 [F] COG2169 Adenosine deaminase
-------------------|||----||||||||-|||----|||||-|||||||----|||||--  0 [D] COG2177 Cell division protein
---||||||--||-------||----||||-------|----|||----------|---|||||--  0 [I] COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)
---------------------|----|||||----|||----|||||-||||-|||---|||||--  0 [K] COG2186 Transcriptional regulators
-----|--|-----------|-----|------|-|--||------|---|||-|-||-|--|---  0 [L] COG2189 Adenine specific DNA methylase Mod
----------------|-||-|---||||||----|||----|||||-||--|--|---|||||||  0 [T] COG2200 FOG: EAL domain
--||--|||--------|-|----||----|-----||----|||||-||--|--|--|||-||--  0 [NT] COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain
|-||----|-----|-||||-|||-||||||----|||----|||||-||--|--|--||||||--  0 [T] COG2202 FOG: PAS/PAC domain
----------------|---|-||||-----------|----|||||-||-|||||||||||||||  0 [T] COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
----------------||-|-|--||----|------|----------||-----|---|--|---  0 [T] COG2206 HD-GYP domain
------------------|||---------||----|-----|||||----------------|--  0 [G] COG2211 Na+/melibiose symporter and related transporters
|-----||-|-------|--||--------|-||-||-----|||||--|--|------|||||--  0 [M] COG2222 Predicted phosphosugar isomerases
-----------|-||------|----||||-------|----|||||-||-----|---|||||--  0 [C] COG2224 Isocitrate lyase
----------||-|-------|----||||-------|----|||||-||-----|---|||||--  0 [C] COG2225 Malate synthase
|-||--||||---||-|--|-------||-|-----||----|||-|-||--|----------|--  0 [R] COG2234 Predicted aminopeptidases
||||||--||||------|||-----|||-|----|----------|--|-----|---||||---  0 [H] COG2241 Precorrin-6B methylase 1
||||||--||||------|||-----|||-|----|----------|--|---------||||---  0 [H] COG2242 Precorrin-6B methylase 2
||||||--||||------|||------||-|----|----------|--|-----|---||||---  0 [H] COG2243 Precorrin-2 methylase
-|----||----------------------------|-----------------------------  0 [M] COG2247 Putative cell wall-binding domain
--|-----------|-----|---------|----||||---|||||-||||-||||||-|-||--  0 [R] COG2249 Putative NADPH-quinone reductase (modulator of drug activity B)
-----------------|------|-----|-----||-----------|------|||----|--  0 [S] COG2257 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB
------------------||------|----|----||----|||-|--|------------|---  0 [S] COG2268 Uncharacterized protein conserved in bacteria
-------------||-|---------|||||----|||---------------------|||||--  0 [R] COG2270 Permeases of the major facilitator superfamily
-------------||--|---------||-|-----||---------------------||-||--  0 [G] COG2273 Beta-glucanase/Beta-glucan synthetase
------------------||----------||-|--||||||-||||-||--||||----|-||--  0 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
--|-----|--||-----||||---|||||------||----|--||-||------------|---  0 [R] COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain
------------------|--|--------|-----|------|||--------------------  0 [T] COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1
---|-----------------|----|---------||----|||||-----|----------|--  0 [S] COG2311 Predicted membrane protein
---|-----------------|-----||-------||----------------------|--|--  0 [R] COG2312 Erythromycin esterase homolog
--------------------||----|----|||-||-----|||||--|-----|---|--||--  0 [S] COG2315 Uncharacterized protein conserved in bacteria
---|--||--|||-------||-------------|||-------|--|-------------|--|  0 [E] COG2317 Zn-dependent carboxypeptidase
------------------|--|--------------||-----------|---------||||---  0 [S] COG2318 Uncharacterized protein conserved in bacteria
--||-----------------|-----|||------||----------||----------------  0 [S] COG2320 Uncharacterized conserved protein
-------------------|||--------||-|--||----|||-|-------------|-----  0 [S] COG2323 Predicted membrane protein
--|---------------|-||--------------||----|||||-||---|||---|||||--  0 [R] COG2334 Putative homoserine kinase type II (protein kinase fold)
-------------------|-|---------------|----|||--------|||---|------  0 [T] COG2336 Growth regulator
----||------------||-|----||||-------|-------|--|-----------------  0 [K] COG2345 Predicted transcriptional regulator
------------------||||----|---|-----|-----|||||-||||-|||---|||||--  0 [S] COG2350 Uncharacterized protein conserved in bacteria
--------------|------|--------------||----|||-|--|-----|--||||||--  0 [R] COG2351 Transthyretin-like protein
------||--|||-|------|||-----------|-|-----------|-----|---|||||--  0 [E] COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog
---------------------|--------------|-----||||||||----------------  0 [L] COG2356 Endonuclease I
---|----|---|-----|--|---------------|----------||-|--------||--||  0 [R] COG2358 TRAP-type uncharacterized transport system, periplasmic component
-----------------|---|--------|-----||----------------------------  0 [S] COG2359 Uncharacterized protein conserved in bacteria
------||----|--------|-------------||------------------|------|---  0 [E] COG2362 D-aminopeptidase
---------------------|----|---|-----||------------||--------------  0 [S] COG2364 Predicted membrane protein
-------------||------|-----||--|---|---------|---|-----|---|---|--  0 [T] COG2365 Protein tyrosine/serine phosphatase
--------|-||---------|--------------||-------||--|-|--------------  0 [Q] COG2368 Aromatic ring hydroxylase
-|-------------------|-------------|--------|-----|-|||-----------  0 [S] COG2369 Uncharacterized protein, homolog of phage Mu protein gp30
---------------------|----|--------|||----|||||--------|----|-|---  0 [R] COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC
------------------||||--------|-----||----------------------------  0 [D] COG2385 Sporulation protein and related proteins
--||-------||-------|---------------|-------------------|||-------  0 [R] COG2404 Predicted phosphohydrolase (DHH superfamily)
------||---||-|--|-|---------------|-|----------------------|--|--  0 [C] COG2421 Predicted acetamidase/formamidase
------|||---|------------------------|----------------------------  0 [S] COG2426 Predicted membrane protein
-------||--------|--|---------||-|---|----------------------------  0 [S] COG2461 Uncharacterized conserved protein
---------------------|----||||||||-|||-----------|---------|------  0 [TQ] COG2508 Regulator of polyketide synthase expression
--|---||||||-----||-|---------||-----|----------|--------------|--  0 [R] COG2509 Uncharacterized FAD-dependent dehydrogenases
----||----|||------|------|||------|||----|||-|-||--||||----|-||--  0 [G] COG2513 PEP phosphonomutase and related enzymes
------------------------------|----|||----|||||---||-||-----------  0 [S] COG2707 Predicted membrane protein
------------------|-----------|-----||-----------|-----|----------  0 [R] COG2715 Uncharacterized membrane protein, required for spore maturation in B.subtilis.
---|--------------------------|-----||----|||||-||----------|-|---  0 [S] COG2718 Uncharacterized conserved protein
---|--------------------------|-----||----|||||-||----------|-|---  0 [S] COG2719 Uncharacterized conserved protein
---------------------|----|---|-----||-----------|----------------  0 [V] COG2720 Uncharacterized vancomycin resistance protein
----|------|------------------|-----||----|||||--------|--||||||--  0 [G] COG2721 Altronate dehydratase
------||-----||--|-|----------|-----||--------------|--|----------  0 [G] COG2730 Endoglucanase
------------------------------|-----|-----|||||------|------------  0 [K] COG2732 Barstar, RNAse (barnase) inhibitor
-------------------|-|--------|----||---------------------|-|-|---  0 [V] COG2746 Aminoglycoside N3'-acetyltransferase
----------------||------------|-----||----|||||-||-----|----------  0 [KNU] COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor)
-----------|-||---||-------|||||||-|||----|||||-||-|-|||--||||||--  0 [E] COG2755 Lysophospholipase L1 and related esterases
---|--------------------------|-----||----|||||-||----------|-|---  0 [T] COG2766 Putative Ser protein kinase
--|-----|-------|-||-|--------------|-----------||-----|---||-|---  0 [T] COG2770 FOG: HAMP domain
---------------------|----|---|--|-||-----|||-|--|-----|--|--|----  0 [P] COG2807 Cyanate permease
-------------|-------|--------------||-----------|--|--|------||--  0 [K] COG2808 Transcriptional regulator
---------------------|--------|--|--|------||-|--|---|----||---|--  0 [R] COG2819 Predicted hydrolase of the alpha/beta superfamily
--------------------------|----|||-|------|||||-||||-|||||||||||--  0 [P] COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism
--------------------------|||--|-|---|-|--|||--------|||---||--|--  0 [L] COG2826 Transposase and inactivated derivatives, IS30 family
------------------------------------|-----|||---||--||||---||-|---  0 [S] COG2828 Uncharacterized protein conserved in bacteria
-|||----|-------|----|--||----|-----||----|||||-||||||||||||||||||  0 [M] COG2834 Outer membrane lipoprotein-sorting protein
--|------------------|-----||---||-||----------------||-----|-||--  0 [M] COG2843 Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
-||------||||-------------|---||-|-|-----------------||-----------  0 [S] COG2848 Uncharacterized conserved protein
--------------------|-||------------|--------||--|---||---|-------  0 [S] COG2849 Uncharacterized protein conserved in bacteria
------------------------------------|-----|||||--|||||||----------  0 [S] COG2850 Uncharacterized conserved protein
-------------------|-|-------------|------|-------|--||-----|--|--  0 [S] COG2852 Uncharacterized protein conserved in bacteria
-------------||-|-------------------||----------||--||||||||||||||  0 [C] COG2857 Cytochrome c1
---|------||---------|----|----||---||----|||||-||||---|--||||||--  0 [S] COG2860 Predicted membrane protein
-------------------------|-----------|----|||-|--|||------|||-||--  0 [S] COG2861 Uncharacterized protein conserved in bacteria
--|----------||---|-----------------||----|||||--|---|||-------|--  0 [E] COG2866 Predicted carboxypeptidase
--|-||||--||||---|--||--------|------|----------||-----|---||||---  0 [R] COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain
--||---------||--|---|----|||-||---|-|-----------|-|---|--|||||---  0 [E] COG2873 O-acetylhomoserine sulfhydrylase
||||||--||||------|||------||-|----|----------|--|-----|---||||---  0 [H] COG2875 Precorrin-4 methylase
-----------------|------|-----|-----||----||||||||-----|----------  0 [NUO] COG2882 Flagellar biosynthesis chaperone
-------------------|-|----||||||||-|||----|||||-|||||||----|||||--  0 [D] COG2884 Predicted ATPase involved in cell division
--------------------|---------||||-||-----|||||----|||||---|||||--  0 [G] COG2893 Phosphotransferase system, mannose/fructose-specific component IIA
----------------||||||--------|----|||----||||||||--||||||-||||---  0 [D] COG2894 Septum formation inhibitor-activating ATPase
|--|------|||||-|--|-|----||||-------|----|||||-||-----|---|||||--  0 [P] COG2897 Rhodanese-related sulfurtransferase
--------|-------|---------|----------|----------||----------------  0 [T] COG2905 Predicted signal-transduction protein containing cAMP-binding and CBS domains
-------------------------------|-|-||-----------||-----|--|||-|---  0 [R] COG2910 Putative NADH-flavin reductase
------------------------------|----|------||||||||-|--------------  0 [H] COG2918 Gamma-glutamylcysteine synthetase
---|---------------||-||-------------|-----------|--||||---||-|---  0 [S] COG2928 Uncharacterized conserved protein
------------------------------------|-----------|---|||-----------  0 [L] COG2946 Putative phage replication protein RstA
--||--------------||-------||--------|----|||||-|---|------|||||--  0 [S] COG2968 Uncharacterized conserved protein
--||----------------------||-------|||----|||||-||-|-||----||||---  0 [R] COG3030 Protein affecting phage T7 exclusion by the F plasmid
--------------------|---------------||----|||-|-||----------------  0 [E] COG3048 D-serine dehydratase
--------------------|-----|----------|----|--||-||||-------||--|--  0 [G] COG3090 TRAP-type C4-dicarboxylate transport system, small permease component
-----------------------------------||-----|||||-||||--------------  0 [T] COG3103 SH3 domain protein
--------------------|----------|||-|------|||||-|--||------||-||--  0 [P] COG3142 Uncharacterized protein involved in copper resistance
-----------------|------------|-----||----||||||||-----|----------  0 [N] COG3144 Flagellar hook-length control protein
---------------------|----|---------|-----|||||--|--|-------------  0 [S] COG3162 Predicted membrane protein
--||-----------------|-----||--|---|||-----------|-----|---||-||-|  0 [R] COG3173 Predicted aminoglycoside phosphotransferase
--------------------|-----|---------||--------|-||-|---|---||-----  0 [S] COG3181 Uncharacterized protein conserved in bacteria
----------------------||------------||----||||||||-----|----------  0 [N] COG3190 Flagellar biogenesis protein
--------------------|--------------||-----|||-|--|----------------  0 [E] COG3192 Ethanolamine utilization protein
----------||------|----------------|------|---|--|-----|---|-|||--  0 [R] COG3193 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol
---------------------|----|---------||-----------|-----|---|||||--  0 [S] COG3195 Uncharacterized protein conserved in bacteria
-------------------|-------||||-----||-------|---|-----|---|--|---  0 [Q] COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis
--|---------------------------|----||-----|||||--|-----|------|---  0 [M] COG3209 Rhs family protein
-------------------|-----------------|----------||--------|||-||--  0 [R] COG3211 Predicted phosphatase
-------------------------------|---||-----|||||--||---------------  0 [S] COG3223 Predicted membrane protein
------------------||-------||-------|------------|-----|----|-||--  0 [I] COG3239 Fatty acid desaturase
-----------|-----|-------------|||---|----||||------|------||-----  0 [G] COG3250 Beta-galactosidase/beta-glucuronidase
---------------------------||-------|------|--|--|-----|---|------  0 [S] COG3251 Uncharacterized protein conserved in bacteria
----||-----------------------------|||----|||||-----------|||||---  0 [S] COG3254 Uncharacterized conserved protein
----||--|-|||---|--------------------|-----------|------------||--  0 [I] COG3255 Putative sterol carrier protein
--------------------|----------------|----|||-|-||---------|--|---  0 [P] COG3263 NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain
-------------------|----------|-----||----|-----||-----|---|||||--  0 [QK] COG3284 Transcriptional activator of acetoin/glycerol metabolism
---------------------------||-------||-----------|---------||-|---  0 [L] COG3285 Predicted eukaryotic-type DNA primase
--------------------------|-----|---||----|||-|-|-----------------  0 [T] COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism
|||---|-|---|------------------|-----|----------|-----------------  0 [R] COG3291 FOG: PKD repeat
-----------------------------------||-----|-||----|-|-|-----------  0 [S] COG3299 Uncharacterized homolog of phage Mu protein gp47
------------------|-----------------|---------|--|-----|---||-||--  0 [T] COG3300 MHYT domain (predicted integral membrane sensor domain)
--|----------------||------|||------|-----------||-|--------|-|---  0 [Q] COG3315 O-Methyltransferase involved in polyketide biosynthesis
----------------------||------------|-----|||-|-||---||-----------  0 [R] COG3318 Predicted metal-binding protein related to the C-terminal domain of SecA
-------------------|------||||------|-----|||||--|-----|-----||---  0 [Q] COG3319 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases
-------------------|------|||||-----|--------|---------|---||-|---  0 [Q] COG3321 Polyketide synthase modules and related proteins
--|-----------------------|||--------|--------|-||-|---|---|||||--  0 [R] COG3324 Predicted enzyme related to lactoylglutathione lyase
---|---------|---------------------|-|--------|-|-----------------  0 [G] COG3325 Chitinase
--|----------------------------|||-|||--------|--|---||-|--|------  0 [S] COG3326 Predicted membrane protein
-----------|---------------||--------|----|-----------------|-----  0 [K] COG3327 Phenylacetic acid-responsive transcriptional repressor
--|-||-----|------|--------||-||-----||----||||--------|----|-|---  0 [L] COG3328 Transposase and inactivated derivatives
------------------||-------||--------|-------------------------|--  0 [R] COG3329 Predicted permease
-----------------|||----------|------|----------------------------  0 [S] COG3330 Uncharacterized protein conserved in bacteria
-------------|-----------------------|-----------|-----|----------  0 [S] COG3332 Uncharacterized conserved protein
--------------------|-----|----------|--------|-||-|---|---||-----  0 [S] COG3333 Uncharacterized protein conserved in bacteria
----------------|-------------------||------------------||||||||--  0 [S] COG3334 Uncharacterized conserved protein
--|--|--|--|------||-|----|------|---|-----||-|-------||----|-|---  0 [L] COG3335 Transposase and inactivated derivatives
---------------------|----||||------||----------------------|-|---  0 [S] COG3336 Predicted membrane protein
--------|-------|--------------------|----------------------------  0 [L] COG3337 Uncharacterized protein predicted to be involved in DNA repair
-------------------|---------------|-|----------|--|----||--|-|---  0 [P] COG3338 Carbonic anhydrase
|-|---------------||----------|-----||-----------------|---|||||--  0 [S] COG3339 Uncharacterized conserved protein
-------------------|||----|--------|||----|||-|---||--------------  0 [E] COG3340 Peptidase E
-------------||--|------------|------|----------------------------  0 [R] COG3341 Predicted double-stranded RNA/RNA-DNA hybrid binding protein
---|------|||------------------------|-----------|----------------  0 [S] COG3342 Uncharacterized conserved protein
-----------------|---------------|---|-------|--|-----------------  0 [G] COG3345 Alpha-galactosidase
----|-------------|-----------------||-------|-------------||-|---  0 [S] COG3347 Uncharacterized conserved protein
|-||--------------------------|-----||----------------------------  0 [L] COG3359 Predicted exonuclease
---|-----------------------||-------|-----------------------------  0 [S] COG3361 Uncharacterized conserved protein
--|-||--|---------------------------||----------------------------  0 [S] COG3377 Uncharacterized conserved protein
---|-------|-------|------|||--||--|-------|||------|--|----------  0 [R] COG3378 Predicted ATPase
---------||||-----------------|||---||--------|--|-----|------|---  0 [S] COG3382 Uncharacterized conserved protein
--||-|-----|------||-|---------------|----|------------|----|-----  0 [L] COG3385 FOG: Transposase and inactivated derivatives
--|-|------|-------|-|--||-||-|-----||----|||-|--|-----|----|-|---  0 [S] COG3391 Uncharacterized conserved protein
--------------------|----------------|------------------|||-------  0 [L] COG3392 Adenine-specific DNA methylase
--|----------------|----|--||------|-|-------------------------|--  0 [R] COG3393 Predicted acetyltransferase
-----------------------------------|-|----|||||-|------------||---  0 [S] COG3394 Uncharacterized protein conserved in bacteria
------------------|||----------------|----|--||---||-------||||---  0 [S] COG3395 Uncharacterized protein conserved in bacteria
-----------|---------|---------------|----|------------|----|-----  0 [S] COG3396 Uncharacterized conserved protein
-------------------------------|---|-|-------|--||----------------  0 [S] COG3397 Uncharacterized protein conserved in bacteria
------------------------------------||------------------|||-------  0 [R] COG3401 Fibronectin type 3 domain-containing protein
---|-----------------|--------------|-----------------------------  0 [S] COG3403 Uncharacterized conserved protein
----------------|--------------------|----|||-|------------|------  0 [G] COG3405 Endoglucanase Y
--|-||||---|-|-----|-|---------------|----------------------|-|---  0 [G] COG3408 Glycogen debranching enzyme
--|---------------||-|----|||||-----||----------|------|---||||---  0 [M] COG3409 Putative peptidoglycan-binding domain-containing protein
----|------|-|-----------------------|----------------------------  0 [S] COG3410 Uncharacterized conserved protein
---|------------||||-|---------------|-----------------|----------  0 [C] COG3411 Ferredoxin
---|----|--|-------|-|---------------|----------------------|-|---  0 [L] COG3415 Transposase and inactivated derivatives
---------------------|-----||-------||----------------------------  0 [Q] COG3424 Predicted naringenin-chalcone synthase
-----------------|---|--------|----||-----------------------------  0 [C] COG3426 Butyrate kinase
---------------------------||-------|-----|||||-||-----------|----  0 [Q] COG3433 Aryl carrier domain
----------------|-------------------|-----------|-----------------  0 [T] COG3434 Predicted signal transduction protein containing EAL and modified HD-GYP domains
-----------|--------------|----------|-----||-|--|-----|----------  0 [Q] COG3435 Gentisate 1,2-dioxygenase
--------------------|---------||||-||-----|||||----|--------------  0 [G] COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB
------------------------------|----|||----|||-|--------|------||--  0 [L] COG3449 DNA gyrase inhibitor
-----------------|---------------|--||---------------------|--|---  0 [Q] COG3458 Acetyl esterase (deacetylase)
-----------------|------------|----|---------|--|----------||||---  0 [G] COG3459 Cellobiose phosphorylase
---------------------|---------------|----|------------|----|-----  0 [Q] COG3460 Uncharacterized enzyme of phenylacetate metabolism
----||--|---------------------------||----------------------------  0 [S] COG3465 Uncharacterized conserved protein
|-|||--------------|||--------||-----|--------|------|||----|||---  0 [R] COG3467 Predicted flavin-nucleotide-binding protein
-------------------------------|---|------------||----------------  0 [G] COG3469 Chitinase
--|-----|-----|---||----------||----|----------------------||-----  0 [T] COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
-||-----------------|----------|----|-----------------------------  0 [R] COG3478 Predicted nucleic-acid-binding protein containing a Zn-ribbon domain
-------------------------------|----|-----------|-----------------  0 [Q] COG3479 Phenolic acid decarboxylase
--------------------------||||-|||-|||----------------------------  0 [T] COG3480 Predicted secreted protein containing a PDZ domain
---|----------|----|-----------------|-------|---|-----|----|-|---  0 [Q] COG3486 Lysine/ornithine N-monooxygenase
--------------------|----------||---||--------|-|-----------------  0 [C] COG3493 Na+/citrate symporter
------------------------------||----||----|-----------------|--|--  0 [G] COG3507 Beta-xylosidase
--------------------------------|--|---------------|--|---|-------  0 [S] COG3513 Uncharacterized protein conserved in bacteria
-----------------|-------------------|-----||-|------------||-||--  0 [S] COG3533 Uncharacterized protein conserved in bacteria
-----------------|------------|-----||---------------------||-||--  0 [G] COG3534 Alpha-L-arabinofuranosidase
------|----|-----------------------|-|---------------------|--|---  0 [S] COG3535 Uncharacterized conserved protein
--------------|----------------|||-|-|--------------|-------------  0 [S] COG3538 Uncharacterized conserved protein
-------------------|------|---------|------------|----------|-||--  0 [P] COG3540 Phosphodiesterase/alkaline phosphatase D
-|-----------------|----------|-----|------------|-----|------|---  0 [R] COG3541 Predicted nucleotidyltransferase
----------|--------|----------|-----||-----||-|--|----------------  0 [P] COG3546 Mn-containing catalase
--|--------|-------||-----||||--||---|-------|---|---||----||-||--  0 [L] COG3547 Transposase and inactivated derivatives
-------------------------------------|-----------|------------|---  0 [S] COG3551 Uncharacterized protein conserved in bacteria
--------------------------|||--|-----|----------------------------  0 [M] COG3559 Putative exporter of polyketide antibiotics
---------------------------||--------|----------------------|||---  0 [S] COG3564 Uncharacterized protein conserved in bacteria
-----------------------------------|--------------|-|---------|---  0 [S] COG3566 Uncharacterized protein conserved in bacteria
-----------------------------------|--------------|-|---------|---  0 [S] COG3567 Uncharacterized protein conserved in bacteria
--------------------------------||-|------|||-|--|--|--|---|||||--  0 [R] COG3568 Metal-dependent hydrolase
-------------|----------|------|||-|------------------------------  0 [E] COG3579 Aminopeptidase C
----------------||--|---------||---|------------------------------  0 [S] COG3580 Uncharacterized protein conserved in bacteria
----------------||--|---------||---|------------------------------  0 [S] COG3581 Uncharacterized protein conserved in bacteria
--------------------------|||||----|||----------------------------  0 [S] COG3583 Uncharacterized protein conserved in bacteria
-----------------|---|--------||---|||----------------------------  0 [S] COG3584 Uncharacterized protein conserved in bacteria
--|----------------------------|---|------|||-----------------|---  0 [S] COG3592 Uncharacterized conserved protein
------||----------------------||---|||-------|--------------------  0 [S] COG3595 Uncharacterized conserved protein
-------------------------------||--|-------|||---||-|--------|----  0 [K] COG3617 Prophage antirepressor
--|---------------|-|------||-||||-||------------|-----|---||||---  0 [S] COG3619 Predicted membrane protein
-------------------|----------------|-----------|---------------||  0 [R] COG3621 Patatin
--||-----------------|-----||-------|------------|---------|--||--  0 [R] COG3631 Ketosteroid isomerase-related protein
-------------------------------|-|-||------||-----||--------------  0 [S] COG3646 Uncharacterized phage-encoded protein
--------------|------|--------------||----------------------------  0 [Q] COG3648 Uricase (urate oxidase)
-----------------|--------------|----|----------------------------  0 [L] COG3649 Uncharacterized protein predicted to be involved in DNA repair
-------------------|------|---|-||-|||-----------|-------------|--  0 [K] COG3655 Predicted transcriptional regulator
-----------------|-------------------|-------------------------|--  0 [G] COG3661 Alpha-glucuronidase
--------------|------|--------------|----------------------||--|--  0 [S] COG3665 Uncharacterized conserved protein
------------------||----------|-||-|||----------------------------  0 [S] COG3689 Predicted membrane protein
-----------------|-|----------|------|---------------------|---|--  0 [G] COG3693 Beta-1,4-xylanase
--------------|------|----|||--|---|------|||||-||----------------  0 [L] COG3695 Predicted methylated DNA-protein cysteine methyltransferase
-------------||---------------------|-----|||----------|---|||||--  0 [P] COG3703 Uncharacterized protein involved in cation transport
----------------|-||-|--------||---|||-----------|---|||---|||||--  0 [E] COG3705 ATP phosphoribosyltransferase involved in histidine biosynthesis
-----------------|||-----|-----------|-----------|--------||||||||  0 [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain
--------------------|------||||----|-------------|-----|---||-||--  0 [T] COG3707 Response regulator with putative antiterminator output domain
---------------------------||--------|----|||||-|-----------|-|---  0 [K] COG3710 DNA-binding winged-HTH domains
--------------------|---------||||-||-----|||||----|--------------  0 [G] COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC
--------------------|---------||||-||-----|||||----|--------------  0 [G] COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID
------------------------------------||----|||||------------||--|--  0 [G] COG3717 5-keto 4-deoxyuronate isomerase
--------------------------|--------|||-------||--------|---|||||--  0 [G] COG3718 Uncharacterized enzyme involved in inositol metabolism
-------------------|----------------|-----|||-|--|-------------|--  0 [R] COG3729 General stress protein
-----------------------------------|-|----|||-|----|----------|---  0 [G] COG3730 Phosphotransferase system sorbitol-specific component IIC
-----------------------------------|-|----|||-|----|----------|---  0 [G] COG3731 Phosphotransferase system sorbitol-specific component IIA
-----------------------------------|-|----||--|----|----------|---  0 [G] COG3732 Phosphotransferase system sorbitol-specific component IIBC
-------------------------------|---|||-------------|-------|---|--  0 [S] COG3739 Uncharacterized integral membrane protein
---------------------------||--|---|-------||-|--------|---|---|--  0 [R] COG3740 Phage head maturation protease
--------------|------------||--|---|-----------------------|--||--  0 [S] COG3752 Predicted membrane protein
------------------------------------||----|||-|--------|---|---|--  0 [S] COG3766 Predicted membrane protein
------------------------------|-----||---------------------|||||--  0 [M] COG3773 Cell wall hydrolyses involved in spore germination
---------------------------||||----|-----------------------|||||--  0 [S] COG3786 Uncharacterized protein conserved in bacteria
---------------------------||----|-|-----------------------||-||--  0 [S] COG3797 Uncharacterized protein conserved in bacteria
------------------------------------|------|||-----|---------||---  0 [R] COG3822 ABC-type sugar transport system, auxiliary component
-------------------------------------|---------------------||-||--  0 [S] COG3828 Uncharacterized protein conserved in bacteria
----------------|-------------|----|||----|||-|--|-----|----------  0 [KT] COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
-||-----|||---------------||||||-|-|-------------|---||-----------  0 [T] COG3830 ACT domain-containing protein
------------------------------|-----||----|||||-|||---------------  0 [KT] COG3835 Sugar diacid utilization regulator
---|--|||-|-|----|-|-|--||----||||-||-||||-------|-----|---||||---  0 [R] COG3845 ABC-type uncharacterized transport systems, ATPase components
------------------||----------|-----||----------------------------  0 [S] COG3854 Uncharacterized protein conserved in bacteria
---------------------------||-|-----||----------------------------  0 [S] COG3856 Uncharacterized conserved protein (small basic protein)
------------------------------|-----||--------------|-------------  0 [R] COG3858 Predicted glycosyl hydrolase
------------------------------|||--|||----------------------------  0 [S] COG3859 Predicted membrane protein
-------------------|-|--------|------|----------------------------  0 [S] COG3860 Uncharacterized protein conserved in bacteria
-------------------|-|--------|-----|-----------------------------  0 [S] COG3861 Uncharacterized protein conserved in bacteria
--------|---------------------|-----|-----------------------------  0 [S] COG3863 Uncharacterized distant relative of cell wall-associated hydrolases
-----------------|------------|-----||----------------------------  0 [G] COG3866 Pectate lyase
-----------------|------------|-----||-------|--------------------  0 [G] COG3867 Arabinogalactan endo-1,4-beta-galactosidase
-----------------|--|---------|----|||----------------------------  0 [R] COG3872 Predicted metal-dependent enzyme
|-|---------------------------|-----||----------------------------  0 [S] COG3874 Uncharacterized conserved protein
----------------------||------|-----||----------------------------  0 [S] COG3876 Uncharacterized protein conserved in bacteria
---------------------------||-|-----||----------------------------  0 [S] COG3879 Uncharacterized protein conserved in bacteria
---------------------|--------|-----||----------------------------  0 [S] COG3881 Uncharacterized protein conserved in bacteria
------------------------------|------|--------------------|-|-----  0 [Q] COG3882 Predicted enzyme involved in methoxymalonyl-ACP biosynthesis
------------------------------||||-|||----------------------------  0 [S] COG3883 Uncharacterized protein conserved in bacteria
--|-----------------------|----------|---------------------|--|---  0 [R] COG3910 Predicted ATPase
|-|---------------|||------||||----|-----------------------|||||--  0 [T] COG3920 Signal transduction histidine kinase
------------------------------|----||---------|-------------------  0 [K] COG3933 Transcriptional antiterminator
--|---------------||----------|------|----------------------------  0 [S] COG3937 Uncharacterized conserved protein
------------------------------|------|--------|-------------------  0 [R] COG3940 Predicted beta-xylosidase
---------------------|--------|------|----------------------------  0 [T] COG3947 Response regulator containing CheY-like receiver and SARP domains
--------------------------|--------|||-------||--------|---|||||--  0 [E] COG3962 Acetolactate synthase
-------------------------------------|-------|-------------||||---  0 [I] COG3963 Phospholipid N-methyltransferase
-------------------------------------|-------|--|----------||-----  0 [P] COG3965 Predicted Co/Zn/Cd cation transporters
-------------------|----------||----|------------------|---||-----  0 [M] COG3967 Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
-------------------------------||--|------|||-|--|-----|----------  0 [R] COG3969 Predicted phosphoadenosine phosphosulfate sulfotransferase
---------------------|----|---|-----|-----------------------------  0 [R] COG3973 Superfamily I DNA and RNA helicases
---|---------------------------|---|-|-------||-||----------------  0 [R] COG3979 Uncharacterized protein contain chitin-binding domain type 3
-|----------------------------|-----|-------------------|-|----|--  0 [M] COG3980 Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase
--------------------||----|---||||---|----------|--|----------|---  0 [R] COG3981 Predicted acetyltransferase
------||-|---------------------------|----------------------------  0 [S] COG4043 Uncharacterized conserved protein
||-------|--------------------------||----------------------------  0 [R] COG4085 Predicted RNA-binding protein, contains TRAM domain
|--------|--------------------|--|--||----------------------------  0 [S] COG4086 Predicted secreted protein
-------------------|---------------|-|---------------------|-||---  0 [E] COG4091 Predicted homoserine dehydrogenase
-------------------------------------|----|||||-------------|-----  0 [R] COG4114 Uncharacterized Fe-S protein
------------------------------|-----|----------------------||||---  0 [G] COG4124 Beta-mannanase
-------------------------------------|----|||-----||--------------  0 [R] COG4146 Predicted symporter
--------|-------|--|-|----|---------||----|||||-||--|--|----------  0 [R] COG4147 Predicted symporter
--|----------------------|-----||--||-----|||||--|-----|---||||---  0 [E] COG4175 ABC-type proline/glycine betaine transport system, ATPase component
--|----------------------|-----||--||-----|||||--|-----|---||||---  0 [E] COG4176 ABC-type proline/glycine betaine transport system, permease component
-|------|-|||----|||||----|------|---|----|||||--|-----|--|||||---  0 [E] COG4177 ABC-type branched-chain amino acid transport system, permease component
---------------------|--------|-----|-----------------------|-----  0 [E] COG4187 Arginine degradation protein (predicted deacylase)
------------------||-----------------|-----------|-----|---|---|--  0 [R] COG4188 Predicted dienelactone hydrolase
-------------------------------------|---------------------||-|---  0 [K] COG4189 Predicted transcriptional regulator
----|------|--------------|---|----|------------------------------  0 [R] COG4194 Predicted membrane protein
---------------------------||-------|-------------------------|---  0 [R] COG4195 Phage-related replication protein
----||-----------|------------|----|------------------------------  0 [S] COG4198 Uncharacterized conserved protein
------------------------------|------|-------------------------|--  0 [S] COG4200 Uncharacterized protein conserved in bacteria
------------------||-------||--------|----|||||-||--||||---|||||--  0 [P] COG4208 ABC-type sulfate transport system, permease component
-------------------------------|||-|||---------------------|------  0 [G] COG4209 ABC-type polysaccharide transport system, permease component
-------------------------------------|-|--||||----|----|---||||---  0 [G] COG4213 ABC-type xylose transport system, periplasmic component
-------------------------------------|-|--||||----|----|---||||---  0 [G] COG4214 ABC-type xylose transport system, permease component
------------------------------|-----||-------||------------|------  0 [R] COG4225 Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
-------------------|----------------|--------------------------|--  0 [I] COG4247 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
-------------------------------|----||-----------------|----------  0 [S] COG4260 Putative virion core protein (lumpy skin disease virus)
----||-----|-------------------|---|------------------------------  0 [S] COG4272 Predicted membrane protein
---|---------------|------|----------|----------------------------  0 [S] COG4276 Uncharacterized conserved protein
-------------|------|----------|-|-|---------------|--------------  0 [S] COG4283 Uncharacterized conserved protein
--------------|----|-|--------------||----------------------------  0 [L] COG4294 UV damage repair endonuclease
---------------------|--------------|----------------------||-----  0 [S] COG4297 Uncharacterized protein containing double-stranded beta helix domain
--------------------|---------|----|------|||-|--|-----|----------  0 [E] COG4302 Ethanolamine ammonia-lyase, small subunit
--------------------|---------|----|------|||-|--|-----|----------  0 [E] COG4303 Ethanolamine ammonia-lyase, large subunit
------------------------------------|---------------|--|----------  0 [G] COG4305 Endoglucanase C-terminal domain/subunit and related proteins
-------------------------------------|-----------|-----|---||-----  0 [S] COG4317 Uncharacterized protein conserved in bacteria
-------------------|----------------|------------|-----|----|-|---  0 [S] COG4319 Ketosteroid isomerase homolog
-------------------|----------------|-----------|-----------------  0 [R] COG4326 Sporulation control protein
-------------------|-----------------|----------|------|----------  0 [S] COG4327 Predicted membrane protein
-------------------|-----------------|----------------------|-----  0 [S] COG4329 Predicted membrane protein
------------------------------------|--------------|-------|------  0 [L] COG4335 DNA alkylation repair enzyme
--------------|-----------|---------|------------|---------|------  0 [S] COG4336 Uncharacterized conserved protein
-------------||---------------|-----|-----------------------------  0 [E] COG4359 Uncharacterized conserved protein, possibly involved in methylthioadenosine recycling
---------------------------------|--|------------------|----------  0 [S] COG4377 Predicted membrane protein
------------------------------|------|--------------------|-------  0 [S] COG4378 Uncharacterized protein conserved in bacteria
------------------||---------------|||----------------------------  0 [E] COG4401 Chorismate mutase
-------------------|----------|-||---|----------------------------  0 [V] COG4403 Lantibiotic modifying enzyme
------------------------------||-|-|||-----|-||-------------------  0 [S] COG4405 Uncharacterized protein conserved in bacteria
------------------------------|-----|-----------|-----------------  0 [S] COG4412 Uncharacterized protein conserved in bacteria
-------------------------------------|-------------------------|-|  0 [G] COG4421 Capsular polysaccharide biosynthesis protein
------------------------|-----||||-|------------------------------  0 [S] COG4443 Uncharacterized protein conserved in bacteria
--------------------|---------||-|--||----------------------------  0 [G] COG4468 Galactose-1-phosphate uridyltransferase
------------------------------|------|-|--------------------------  0 [S] COG4508 Uncharacterized protein conserved in bacteria
---------------------|-------------|||----|||||-|-----------------  0 [R] COG4533 ABC-type uncharacterized transport system, periplasmic component
------------------------------|----|----------|---------------|---  0 [Q] COG4542 Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase
-----------------------------------||----------------------||||---  0 [S] COG4549 Uncharacterized protein conserved in bacteria
-------------------||------||--|-----|----------------------------  0 [R] COG4552 Predicted acetyltransferase involved in intracellular survival and related acetyltransferases
-----------------|---|--|-----|-----|---------------|-------------  0 [CP] COG4555 ABC-type Na+ transport system, ATPase component
--------------------------|-----|---||----|||-|-|-----------------  0 [KT] COG4565 Response regulator of citrate/malate metabolism
------------------|||--------------|------|||-|-------------------  0 [QC] COG4576 Carbon dioxide concentrating mechanism/carboxysome shell protein
------------------|||--------------|------|||-|-------------------  0 [QC] COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein
--------------------------||||-------|----|||-|----|----------|---  0 [K] COG4578 Glucitol operon activator
---|--|||-|-|----|-|-|--||----||||-||-||||-------|-----|---||||---  0 [R] COG4603 ABC-type uncharacterized transport system, permease component
------------------||-|---------------|----------------------------  0 [S] COG4627 Uncharacterized protein conserved in bacteria
------------------------------||----|-----------------------------  0 [G] COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
------------------------------|-----||----------------------|-----  0 [S] COG4641 Uncharacterized protein conserved in bacteria
--|--------------|--|---||---------|------||||||||||--------------  0 [C] COG4656 Predicted NADH:ubiquinone oxidoreductase, subunit RnfC
---|----|---|--------|---------------|----------||-|--------||----  0 [R] COG4666 TRAP-type uncharacterized transport system, fused permease components
------------------||-|----|----------|-------|---|-----|---||-|---  0 [R] COG4674 Uncharacterized ABC-type transport system, ATPase component
------------------------------------|-----|||||--------|----------  0 [S] COG4682 Predicted membrane protein
------------------------------||||-|------------------------------  0 [S] COG4687 Uncharacterized protein conserved in bacteria
-------------------------------||--|||----------------------------  0 [S] COG4698 Uncharacterized protein conserved in bacteria
-------------------------------|||-||-----------------------------  0 [S] COG4703 Uncharacterized protein conserved in bacteria
------------------------------||||-|------------------------------  0 [S] COG4708 Predicted membrane protein
------------------------------|||--|||----------------------------  0 [S] COG4722 Phage-related protein
-------------------------------|-|---|----------------------------  0 [G] COG4724 Endo-beta-N-acetylglucosaminidase D
---|----|----------------------------|-----------|-|--------------  0 [S] COG4729 Uncharacterized conserved protein
--|----------------|-----||--------|------------------------------  0 [S] COG4748 Uncharacterized conserved protein
--------------------|--------------|------|||-|------------|------  0 [E] COG4766 Ethanolamine utilization protein
--------------------------|---||-|-|-|----------------------------  0 [V] COG4767 Glycopeptide antibiotics resistance protein
-----------------|--|---|------|---|------------------------------  0 [S] COG4769 Predicted membrane protein
----------------||------||----|----|||----||||||||-----|||||||||--  0 [N] COG4786 Flagellar basal body rod protein
---|--|||--|-||--|--||----||||------||-----------|-----|---|||||||  0 [I] COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
-----------------------------------|||----|||||-------------------  0 [G] COG4806 L-rhamnose isomerase
--------------------|--------------|------|||-|-------------------  0 [E] COG4810 Ethanolamine utilization protein
-----------------------------------|------|||||----|--------------  0 [S] COG4811 Predicted membrane protein
--------------------|--------------|------|||-|-------------------  0 [E] COG4812 Ethanolamine utilization cobalamin adenosyltransferase
-----------------------------------|-|---------------------||||---  0 [G] COG4813 Trehalose utilization protein
--------------------|--------------|------|||-|-------------------  0 [E] COG4816 Ethanolamine utilization protein
-------------------------------|---|-|----------------------------  0 [S] COG4817 Uncharacterized protein conserved in bacteria
--------------------|--------------|------|||-|-------------------  0 [E] COG4819 Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition
--------------------|--------------|------|||-|-------------------  0 [E] COG4820 Ethanolamine utilization protein, possible chaperonin
-----------------------------------|-|-----------------------|----  0 [R] COG4821 Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain
--------------------|---------|----|----------|-------------------  0 [H] COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase
--------------------|--------------|---------------|--------------  0 [V] COG4823 Abortive infection bacteriophage resistance protein
------------------------------|----|||----------------------------  0 [R] COG4824 Phage-related holin (Lysis protein)
--------------------------||||-------|----------------------------  0 [S] COG4825 Uncharacterized membrane-anchored protein conserved in bacteria
--|-----------------|----------|---|------------------------------  0 [S] COG4832 Uncharacterized conserved protein
--------------------------|||------|------------------------------  0 [G] COG4833 Predicted glycosyl hydrolase
-----------------------------------|----------------|---------|---  0 [S] COG4834 Uncharacterized protein conserved in bacteria
-------------------------------|||-|------------------------------  0 [S] COG4835 Uncharacterized protein conserved in bacteria
-------------------------------|---|-----------------------|--|---  0 [S] COG4852 Predicted membrane protein
--------------------|---------------|-----------------------|-|---  0 [R] COG4857 Predicted kinase
-------------------------------|||-|------------------------------  0 [S] COG4858 Uncharacterized membrane-bound protein conserved in bacteria
-----------------|-----------------|----------|-------------------  0 [Q] COG4869 Propanediol utilization protein
--------------------|--------------|------|-----------------------  0 [S] COG4884 Uncharacterized protein conserved in bacteria
--|----------|||---|----------|-|--|------|||||--|-----|----------  0 [S] COG4886 Leucine-rich repeat (LRR) protein
--------------------------|||------|--------------------||--------  0 [R] COG4889 Predicted helicase
--|-----------------------|------|--|-----------------------------  0 [S] COG4894 Uncharacterized conserved protein
--|------------------|--------------|-----------------------------  0 [S] COG4895 Uncharacterized conserved protein
---------------------------------|-|------------------------|-----  0 [S] COG4898 Uncharacterized protein conserved in bacteria
------------------------------||---|------------------------------  0 [S] COG4905 Predicted membrane protein
--|------------------------||-|----|------------------------------  0 [R] COG4908 Uncharacterized protein containing a NRPS condensation (elongation) domain
-----------------------------------|----------|---------------|---  0 [Q] COG4909 Propanediol dehydratase, large subunit
-----------------------------------|----------|---------------|---  0 [Q] COG4910 Propanediol dehydratase, small subunit
--|-----------------|-----|----|---|------------------------|-|--|  0 [L] COG4912 Predicted DNA alkylation repair enzyme
--------------------|--------------|------|||-|-------------------  0 [E] COG4917 Ethanolamine utilization protein
-------------------------------|---||-----------------------------  0 [S] COG4918 Uncharacterized protein conserved in bacteria
------------------------------|||--|------------------------------  0 [S] COG4926 Phage-related protein
-------------------------------|---|-|----------------------------  0 [M] COG4932 Predicted outer membrane protein
------------------------------|----|----------|-------------------  0 [TK] COG4936 Predicted sensor domain
----------|------------------------|------------|-----------------  0 [S] COG4938 Uncharacterized conserved protein
--------------------|---|----------|------------------------------  0 [S] COG4939 Major membrane immunogen, membrane-anchored lipoprotein
|-|-------|--------|------|---|-----||----------------------------  0 [KT] COG4978 Transcriptional regulator, effector-binding domain/component
--||-------------------------------|--------------------------|---  0 [S] COG4983 Uncharacterized conserved protein
------------------------------|-----|----------------------||||---  0 [S] COG4991 Uncharacterized protein with a bacterial SH3 domain homologue
------------------------------|----|-------------------|----------  0 [S] COG4994 Uncharacterized protein conserved in bacteria
--------------|---------------------|------------|----------------  0 [R] COG5018 Inhibitor of the KinA pathway to sporulation, predicted exonuclease
--------------|----|----------------|-----------------------------  0 [GM] COG5039 Exopolysaccharide biosynthesis protein
-------------------|-|---------------|-----------------|---|--||--  0 [T] COG5278 Predicted periplasmic ligand-binding sensor domain
------------------------------||---|-------||-|-----|-------------  0 [S] COG5283 Phage-related tail protein
-------------------|----------------|---------------|-------------  0 [S] COG5293 Uncharacterized protein conserved in bacteria
--|-----------------|----------------|-----||||---||||||----|||---  0 [UW] COG5295 Autotransporter adhesin
-----------------------------------||------------------|----------  0 [S] COG5298 Uncharacterized protein conserved in bacteria
--|-----------------------|---------|-----------------------------  0 [M] COG5337 Spore coat assembly protein
-----------------|--|----------|---|------------------------------  0 [S] COG5341 Uncharacterized protein conserved in bacteria
-----------------------------------|-----------------------||||---  0 [R] COG5350 Predicted protein tyrosine phosphatase
-------------------------------|-|-|||----------------------------  0 [S] COG5353 Uncharacterized protein conserved in bacteria
--|--------------------------------|-------------------|----|-||--  0 [S] COG5361 Uncharacterized conserved protein
--|--------------------------------|--------------------------|--|  0 [R] COG5362 Phage-related terminase
-----------------------------------|||--------------|-------------  0 [L] COG5377 Phage-related protein, predicted endonuclease
------------------||----||----------||----------------------------  0 [R] COG5401 Spore germination protein
-----------------------------------|-|--------------|------------|  0 [S] COG5410 Uncharacterized protein conserved in bacteria
--------------------------||||-----|||---------------|||----------  0 [S] COG5416 Uncharacterized integral membrane protein
------|-|-|-------|-------|---------|-----------------------------  0 [S] COG5428 Uncharacterized conserved small protein
-----------------------------------|-|---------------------|-|-|--  0 [S] COG5437 Predicted secreted protein
-------------------------------------|-------|-------------|---|--  0 [S] COG5460 Uncharacterized conserved protein
------------------------------|----||------||||-------------------  0 [N] COG5492 Bacterial surface proteins containing Ig-like domains
-------------||----------------------|----------------------------  0 [M] COG5498 Predicted glycosyl hydrolase
-------|------------|---------------||----------------------------  0 [S] COG5505 Predicted integral membrane protein
--------------------------------||-|||----------------------------  0 [S] COG5506 Uncharacterized conserved protein
-----------------------------------||---------|--------|----------  0 [R] COG5518 Bacteriophage capsid portal protein
------------------------------|-----|---------|----------------|--  0 [M] COG5520 O-Glycosyl hydrolase
--------------------------------||-||-----------------------------  0 [S] COG5521 Predicted integral membrane protein
--------------------|---|-|---------|-----------------------------  0 [S] COG5522 Predicted integral membrane protein
------------------------------||||-|------------------------------  0 [S] COG5523 Predicted integral membrane protein
-------------------|---------------|------|||-|-----|--|----------  0 [R] COG5525 Bacteriophage tail assembly protein
-------------------------------|||-|||----------------------------  0 [S] COG5578 Predicted integral membrane protein
-----------------|------------|-----||----|||||--|----------------  0 [M] COG5581 Predicted glycosyltransferase
------------------------------|-----||-----------|----------------  0 [S] COG5583 Uncharacterized small protein
--|---------------------------|-|----|----------------------------  0 [T] COG5585 NAD+--asparagine ADP-ribosyltransferase
-------------------------------------|-------------------------|-|  0 [R] COG5628 Predicted acetyltransferase
-------------------|----------------|------------------|----------  0 [S] COG5634 Uncharacterized conserved protein
--------------------------|----|---|||-------------------------|--  0 [S] COG5646 Uncharacterized conserved protein
--||-------------|---|--------|----|-|-----------------|----------  0 [S] COG5652 Predicted integral membrane protein
--|-----|-----------------|--------||--------------------------|--  0 [S] COG5658 Predicted integral membrane protein
------------------------|-||||------|-----------------------------  0 [S] COG5660 Predicted integral membrane protein
------------------||----|--||-------||-----------------|---||-|---  0 [K] COG5662 Predicted transmembrane transcriptional regulator (anti-sigma factor)
------------------------------|-----||------------------------|---  0 [S] COG5663 Uncharacterized conserved protein