When Biological networks are no longer scale free. Speaker: Teresa M.Przytycka Time: May 25, 2004, 11:00 am B2 seminar room. Recent studies of properties of various biological networks revealed that many of them display scale free characteristics. Since the theory of scale free networks is applicable to evolving networks, one can hope that it provides not only a model of a biological network in its current state but also sheds some insight into the evolution of the network. In this talk I will start with an introduction to the world of scale free networks, the motivation behind this concept, it’s power and limitations. Subsequently, I will focus on two evolutionary models for domain similarity network and argue that models which include evolutionary drift are typically not scale free. Instead they adhere quite closely to the Yule distribution. This finding indicates that the direct applicability of scale free models in understanding the evolution of biological networks may not be as wide as it has been hoped for.