Wednesday, March 25, 11 AM
Bldg. 38A, B2 conference room

Mutational biases, gene finding and protein evolution

Luciano Brocchieri, University of Florida  College of Medicine

Prokaryote genomes are characterized by a wide range of compositional biases, particularly in regard to GC content. The combination of strong mutational biases 
and negative selection generates strong sequence contrasts that provide means for identifying genes and information on their modes of evolution. The study of the
 effect of different mutational pressures on gene and protein sequences suggests new approaches to modeling protein differentiation and to the reconstruction 
of evolutionary trees.


Luciano Brocchieri, PhD.
Assistant Professor
University of Florida  College of Medicine