From: Marchler-Bauer, Aron (NIH/NLM/NCBI) [E]
Sent: Monday, February 25, 2008 11:57 AM
To: NLM/NCBI List ncbi-seminar
Subject: CBB seminar, Tuesday 2/26/2008, 11 am, B2 Library

CBB Seminar 11:00 am Tue Feb 26, B2 Library

Aron Marchler-Bauer


CDD Super-families: Specific Protein Annotation with NCBI's Conserved
Domain Database

Models of evolutionarily conserved domains provide annotation on a large
fraction of sequences in NCBI's Entrez protein database. The Conserved
Domain Database curation effort establishes a fine-grained
classification of protein families. In future CDD releases, specific
annotation as provided by NCBI-curated models will be distinguished from
non-specific annotation with domain super-family footprints. I will
discuss the rationale for making this distinction and present a preview
of protein domain annotation as provided with the upcoming CDD release
2.14.