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Algorithmic
methods in Computational and Systems Biology
AlgoCSB
Teresa Przytycka,
head
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Research
Interests
The research in AlgoCSB
group concentrates on computational modeling and analysis of biological
processes, with emphases on hypothesis and theory-driven questions that
are enabled by large-scale data analysis using (but not limited to) graph
theoretical and algorithmic approaches.
We frequently look at these processes through evolutionary lenses,
focusing on evolutionary forces that shaped biomolecules on sequence,
structure, and
network levels. We
are particularly interested in the dynamical properties of biological systems including
spatial, temporal and/or contextual variation and exploring how such variations are
impacting gene expression, how they affect network topology, function,
and the phenotype of the organism.
Specific research topics include:
- Systems
Biology Approaches to study Genotype-Phenotype relationship
- Molecular interactions and
networks
- Gene regulation
- Protein and genome
evolution
- Protein, DNA and RNA structure
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