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Algorithmic methods in Computational and Systems Biology

AlgoCSB

Teresa Przytycka, head

Teresa M. Przytycka, PhD

Senior Investigator

NCBI, NLM, NIH

Computational Biology Branch
Building 38a; Room8S812

8600 Rockville Pike
Bethesda, MD 20894

Tel: 301-402 1723; Fax: 301-480-9241
Email: przytyck@ncbi.nlm.nih.gov

See IRP Research in Action editorial about our group

News: Piotr Jakub Wojtowicz, born December 24, 2012

Principal Investigator	Publications	Software and data
Group Members (and some group pictures)	Lecture notes	Book Chapters

Research Interests

The research in AlgoCSB group concentrates on computational modeling and analysis of biological processes, with emphases on hypothesis and theory-driven questions that are enabled by large-scale data analysis using (but not limited to) graph theoretical and algorithmic approaches. We frequently look at these processes through evolutionary lenses, focusing on evolutionary forces that shaped biomolecules on sequence, structure, and network levels. We are particularly interested in the dynamical properties of biological systems including spatial, temporal and/or contextual variation and exploring how such variations are impacting gene expression, how they affect network topology, function, and the phenotype of the organism. Specific research topics include:

• Systems Biology Approaches to study Genotype-Phenotype relationship
• Molecular interactions and networks
• Gene regulation
• Protein and genome evolution
• Protein, DNA and RNA structure