| Computational Biology Branch | |
| Ivan Ovcharenko Research Group | |
| Research Projects | Publications | Collaborations | Resources | Group Members | Principal Investigator | Visiting us |
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Collaborative Projects |
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| Dr. Len Pennacchio Lawrence Berkeley National Laboratory |
Forebrain gene regulation. Computational analysis of sequence motifs specific to forebrain enhancers. Transgenic mouse experimentation. |
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| Dr. Gabriela Loots Lawrence Livermore National Laboratory |
Bone development. Identification of bone development genes and gene regulatory elements. Characterization of limb, cartilage, and bone enhancer elements in transgenic frog, Xenopus tropicalis. |
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| Dr. John Rubenstein University of California, San Francisco |
Forebrain development. Reconstruction of forebrain gene regulatory networks. Identification of upstream regulators responsible for the initiation of regulatory cascades in different sub-domains of the forebrain. |
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| Dr. David Klein NICHD, NIH |
Pineal gland development. Using microarray data to identify enhancer elements and key transcription factors playing role in the pineal gland development. |
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| Dr. Marcelo Nobrega University of Chicago |
Heart regulatory code. Coupled computational identification and experimental validation of gene regulatory elements partaking in heart development. Transgenic zebrafish experimentation. |
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| Dr. Laura Elnitski NHGRI, NIH |
Gene expression repressors. Identification of regulatory elements with repressor function in the human genome. Experimental validation of predicted liver repressors in Hep G2 cell lines. |
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| Dr. Webb Miller Penn State University |
Genome evolution. Development of software resources for evolutionary studies. Comparative genomics analysis of variable gene desert evolution in eukaryotic genomes. |
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| Dr. John Spouge NCBI, NIH |
Sequence pattern analysis. Development of computational methods to identify specific sequence patterns in gene regulatory elements with shared biological functions. |
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