ACGCGT and/or ACGCGT
are found in the upstream regions of these cell cycle-regulated yeast genes:
early_g1: 11 genes
YBR231C
YCL040W GLK1 Glucokinase
YER111C SWI4 transcription factor
YGR281W YOR1 ABC transporter
YJL194W CDC6 pre-initiation complex component
YLR049C
YLR273C PIG1 Protein similar to Gac1p, a putative type 1 protein phosphatase targeting subunit
YLR274W CDC46 MCM initiator complex protein
YML109W ZDS2 Zds1 homolog
YML110C COQ5 Putative mitochondrial C-methyltransferase
YMR007W
late_g1: 67 genes
YAR007C RFA1 69 kDa subunit of the heterotrimeric RPA (RF-A) single-stranded DNA binding protein, binds URS1 and CAR1
YBL035C POL12 B subunit of DNA polymerase alpha-primase complex
YBR088C POL30 profilerating cell nuclear antigen (PCNA); accessory factor for DNA polymerase delta, mRNA increases in G1, peaks in S in mitosis, and increases prior to DNA synthesis in meiosis
YCL024W Ser/Thr protein kinase
YDL003W MCD1 involved in mitosis, similar to pombe Rad21
YDL010W
YDL018C ERP3 p24 protein involved in membrane trafficking
YDL101C DUN1 protein kinase
YDL103C QRI1 UDP-N-acetylglucosamine pyrophosphorylase
YDL105W QRI2
YDL156W
YDL164C CDC9 DNA ligase
YDR097C MSH6 Homolog of the human GTBP protein, forms a complex with Msh2p to repair both single-base and insertion-deletion mispairs, redundant with Msh3p in repair of insertion-deletion mispairs
YDR297W SUR2 Syringomycin response protein 2
YDR309C GIC2 Cdc42 binding protein, involved in bud emergence
YDR383C
YDR507C GIN4 putative serine/threonine kinase
YER070W RNR1 ribonucleotide reductase
YFL008W SMC1 omosome segregation protein
YGR109C CLB6 B-type cyclin
YHR110W ERP5 p24 protein involved in membrane trafficking
YHR153C SPO16 sporulation protein
YHR154W ESC4 involved in silencing
YIL026C IRR1 involved in cell morphology
YIL159W BNR1 involved in actin filament organization
YJL074C SMC3 involved in sister chromatid cohesion
YJL078C PRY3 Similar to plant PR-1 class of pathogen related proteins
YJL181W
YJL196C ELO1 Elongation enzyme 1
YJR043C POL32 third (55 kDa) subunit of DNA polymerase delta
YKL042W SPC42 component of the spindle pole body
YKL045W PRI2 p58 polypeptide of DNA primase
YKL108W SLD2 Synthetically lethal with dpb11-1; required for DNA replication
YKL113C RAD27 42 kDa 5' to 3' exonuclease required for Okazaki fragment processing
YKR077W
YLL022C HIF1 interacts with histone acetyltransferase
YLR032W RAD5 putative ATPase/DNA helicase
YLR103C CDC45 omosomal DNA replication initiation protein
YLR212C TUB4 gamma tubulin-like protein, interacts with Spc98p and Spc97p, the Tub4p-Spc98p-Spc97p complex may be part of the microtubule attachment site at the spindle pole body
YLR313C SPH1 homologous to Spa2p, localizes to sites of polarized growth
YLR382C NAM2 mitochondrial leucyl tRNA synthetase
YLR383W RHC18 involved in recombination repair
YLR457C NBP1 Nap1p binding protein
YML021C UNG1 uracil DNA glycosylase
YML027W YOX1 Homeobox-domain containing protein
YMR179W SPT21 non-specific DNA binding protein
YNL082W PMS1 MutL homolog, similar to Mlh1p, associates with Mlh1p, possibly forming a heterodimer, Pms1p and Msh1p act in concert to bind to a Msh2p-heteroduplex complex containing a G-T mismatch
YNL102W POL1 DNA polymerase I alpha subunit, p180
YNL233W BNI4 Is required to link Chs3p and Chs4p to the septins
YNL262W POL2 DNA polymerase II
YNL273W TOF1 Interacts with topoisomerase I
YNL310C
YNL312W RFA2 subunit 2 of replication factor RF-A; 29% identical to the human p34 subunit of RF-A
YOL017W
YOR074C CDC21 Thymidylate synthase
YOR144C
YPL014W
YPL153C RAD53 protein kinase, Mec1p and Tel1p regulate rad53p phosphorylation
YPL208W
YPL209C IPL1 Protein kinase
YPL241C CIN2 involved in microtubule function
YPL267W
YPR018W RLF2 p90 subunit of yeast omatin Assembly Factor-I (CAF-I)
YPR174C
YPR175W DPB2 DNA polymerase epsilon, subunit B
YMR076C PDS5 (putative) involved in sister chromosome cohesion during mitosis
YMR076C PDS5 (putative) involved in sister chromosome cohesion during mitosis
s: 16 genes
YAR008W SEN34 34kDa subunit of the tetrameric tRNA splicing endonuclease
YBL002W HTB2 Histone H2B (HTB1 and HTB2 code for nearly identical proteins)
YBL003C HTA2 Histone H2A (HTA1 and HTA2 code for nearly identical proteins)
YBR007C
YCR065W HCM1 Transcription factor (fork head domain)
YDL197C ASF2 Anti-silencing protein, involved in transcription
YDR113C PDS1 42-kDa nuclear protein
YDR356W NUF1 component of the spindle pole body that interacts with Spc42p, calmodulin, and a 35 kDa protein
YER016W BIM1 microtubule-binding protein
YER118C SSU81 Transmembrane osmosensor
YFR027W ECO1 involved in establishment of cohesion between sister chromatids
YIL140W SRO4 localizes to the plasma membrane
YJL115W ASF1 involved in silencing
YJR006W HYS2 DNA polymerase delta 55 KD subunit
YMR048W
YOR284W
g2: 0 genes
m: 1 genes
YIL162W SUC2 invertase (sucrose hydrolyzing enzyme)