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I am interested in various problems in evolutinoary genomics. Among the
topics that I investigate are evolution of gene architecture in eukaryotes.
I would like to reveal the functions conveyed by the unique fragmented
architecture of eukaryotic genes, with special emphasis on the cellular
regulatory machinery. I would also like to understand the evolutionary
forces that have led to the wealth of architectures seen across the
eukaryotic domain. At the system level, I believe that adding gene
architecture as a key element in whole-genome studies, and understanding
its interplay with other genic phenotypes, is a crucial issue.
I am also interested in the connections between phenotypic and evlutionary
properties of genes; in deciding between competing phylogenetic topologies;
and in other analyses of genic and genomic properties.
| National Center for Biotechnology Information (NCBI) | |
| National Library of Medicine (NLM) | |
| National Institutes of Health (NIH) | |
| Bldg. 38A, room 5N511H | |
| 8600 Rockville Pike | |
| Bethesda, MD 20894, USA | |
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+1 (301) 594-6478 |
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+1 (301) 435-7794 |
 |
carmel@ncbi.nlm.nih.gov |